CN105327097A - Drug for treating chronic obstructive emphysema - Google Patents
Drug for treating chronic obstructive emphysema Download PDFInfo
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- CN105327097A CN105327097A CN201510785616.9A CN201510785616A CN105327097A CN 105327097 A CN105327097 A CN 105327097A CN 201510785616 A CN201510785616 A CN 201510785616A CN 105327097 A CN105327097 A CN 105327097A
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/536—Prunella or Brunella (selfheal)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention relates to a drug for treating chronic obstructive emphysema. The drug is prepared from, by weight, 10 parts of cortex lycii radicis, 15 parts of rhizoma atractylodis macrocephalae, 9 parts of rhizoma pinelliae, 10 parts of fewflower lysionotus herbs, 12 parts of herba ephedrae, 10 parts of herba pteridis multifidae, 15 parts of bulbus fritillariae ussuriensis, 9 parts of selfheal and 8 parts of fructus perillae. According to the drug, cortex lycii radicis can clear the lung to decrease internal fire; rhizoma atractylodis macrocephalae can strengthen the spleen, benefit Qi, eliminate dampness and promote urination; rhizoma pinelliae can eliminate dampness and dissipate phlegm; fewflower lysionotus herbs can clear heat and remove dampness; herba ephedrae can ventilate the lung, relieve asthma, promote urination and eliminate swelling; herba pteridis multifidae can clear heat and remove dampness; bulbus fritillariae ussuriensis can clear heat, moisten the lung, dissipate phlegm and relieve a cough; selheal can clear fire and remove stasis; fructus perillae can depress Qi and dissolve phlegm. All the traditional Chinese medicines are combined to jointly achieve the effects of nourishing Yin, moistening the lung, nourishing the spleen and strengthening the kidney to effectively treat the chronic obstructive emphysema. Clinical experiments prove that the drug can safely and effectively treat the chronic obstructive emphysema.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of medicine being used for the treatment of chronic obstructive emphysema.
Background technology
Chronic obstructive emphysema is many causes the whole last bronchus far-end of pulmonary excessively inflate and expand by environmental pollution, smoking, infective agent etc., and alveolar elasticity reduces, and volume increases, and airway walls is destroyed, and causes series of symptoms.
Patient's cardinal symptom is dyspnea, and the lighter only occurs when physical work, and along with emphysema degree increases the weight of, dyspnea increases the weight of gradually, even also occurs dyspnea during rest.When merging respiratory tract infection, exacerbation of symptoms, and can anoxia, acidosis etc. be there is.
The treatments such as current doctor trained in Western medicine clinical treatment chronic obstructive emphysema multiselect aminophylline, azithromycin, ciprofloxacin.But cure the symptoms, not the disease more, easily cause Relapse rate to show effect.
Medical material involved in the present invention is recorded in all as seen " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of medicine being used for the treatment of chronic obstructive emphysema, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing chronic obstructive emphysema.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of medicine being used for the treatment of chronic obstructive emphysema, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Cortex Lycii 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, the Rhizoma Pinelliae 9 parts, Herba Lysionoti Pauciflori 10 parts, 12 parts, Herba Ephedrae, Herba Pteridis Multifidae 10 parts, Bulbus Fritillariae Ussuriensis 15 parts, Spica Prunellae 9 parts, Fructus Perillae 8 parts.
Inventor thinks: have disease in lung, and spleen kidney is not good in addition, controls for a long time and not and causes three burnt weaknesses, cloudy gas disappearance.Three burnt raw illness, air water is uncomfortable, water-damp not being transformed.Should note nourishing YIN and moistening the lung in treatment, foster spleen is good for kidney.
The present invention uses: Cortex Lycii lung heat clearing pathogenic fire reducing; Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI, dampness diuretic; Rhizoma Pinelliae drying dampness to eliminate phlegm; Herba Lysionoti Pauciflori clearing away heat-damp and promoting diuresis; Herba Ephedrae depressed lung-energy dispersing, inducing diuresis to remove edema; Herba Pteridis Multifidae clearing away heat-damp and promoting diuresis; Bulbus Fritillariae Ussuriensis clearing heat and moistening lung, preventing phlegm from forming and stopping coughing; Spica Prunellae relieves inflammation or internal heat eliminating stagnation; The expectorant of Fructus Perillae sending down the abnormal ascending QI.All medicines share, and play nourishing YIN and moistening the lung altogether, and foster spleen is good for effect of kidney, effectively treats chronic obstructive emphysema.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects chronic obstructive emphysema patient 50 example for 2012 altogether between year December of December ~ 2014, all from Pneumology Department outpatient service, and 45 ~ 70 years old age, male 35 example, women 15 example.The course of disease 1 year ~ 10 years.
Diagnostic criteria:
Have cough for many years, expectoration symptom, the state of an illness increases the weight of along with the reduction of temperature, and patient feels seriously out of breath in early days after aggravating activities.Later development for speaking, washing one's face, tranquillization and also to labor for breath on foot or out of breath.Some patients thorax anteroposterior diameter increases, the full formation barrel chest in intercostal space, and liver dullness circle declines, and border of cardiac dullness disappears or reduces.Breathing time extends, diminished breath sound.
Meet above-mentioned diagnostic criteria, the patient that the age is greater than 18 years old.
Exclusion standard: trimester of pregnancy, women breast-feeding their children; Merge severe cardiac hepatorenal disease person.
2, test method
The decoct that the oral the present invention of all patients obtains according to embodiment 1, every day 3 times.2 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Judge according to " diagnosis of chronic obstructive emphysema disease and efficacy assessment standard ".
1. invalid: patient treatment terminates rear obstructive emphysema not to be alleviated, and clinical symptoms does not alleviate and even increases the weight of, vital sign is unstable.
2. effective: treatment terminates rear obstructive emphysema and alleviates to some extent, and clinical symptoms disappears substantially, and patient normally can work and live substantially, but treat in latter 1 year and occur rebound phenomenon.
3. fully recover: treatment terminates rear patient's clinical symptoms and disappears completely, recover normal and do and life, without rebound phenomenon.
3.2 therapeutic outcome
50 routine patients fully recover 32 example, effective 14 example, invalid 4 example, total effective rate 92%.There is laxativeness in treatments period 1 example, has no other obvious adverse reaction.It is safe and effective that visible the present invention is used for the treatment of chronic obstructive emphysema, has the value applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Cortex Lycii 10 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, the Rhizoma Pinelliae 9 grams, Herba Lysionoti Pauciflori 10 grams, 12 grams, Herba Ephedrae, Herba Pteridis Multifidae 10 grams, Bulbus Fritillariae Ussuriensis 15 grams, Spica Prunellae 9 grams, Fructus Perillae 8 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of chronic obstructive emphysema.Oral, every bu morning, noon and afternoon take for three times.
Embodiment 2
Take: Cortex Lycii 10 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, the Rhizoma Pinelliae 9 grams, Herba Lysionoti Pauciflori 10 grams, 12 grams, Herba Ephedrae, Herba Pteridis Multifidae 10 grams, Bulbus Fritillariae Ussuriensis 15 grams, Spica Prunellae 9 grams, Fructus Perillae 8 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of chronic obstructive emphysema.Oral, daily once.
Embodiment 3
Take: Cortex Lycii 10 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, the Rhizoma Pinelliae 9 grams, Herba Lysionoti Pauciflori 10 grams, 12 grams, Herba Ephedrae, Herba Pteridis Multifidae 10 grams, Bulbus Fritillariae Ussuriensis 15 grams, Spica Prunellae 9 grams, Fructus Perillae 8 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of chronic obstructive emphysema.Oral, every bu is taken for twice sooner or later.
Claims (4)
1. one kind is used for the treatment of the medicine of chronic obstructive emphysema, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Cortex Lycii 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, the Rhizoma Pinelliae 9 parts, Herba Lysionoti Pauciflori 10 parts, 12 parts, Herba Ephedrae, Herba Pteridis Multifidae 10 parts, Bulbus Fritillariae Ussuriensis 15 parts, Spica Prunellae 9 parts, Fructus Perillae 8 parts.
2. be used for the treatment of the medicine of chronic obstructive emphysema as claimed in claim 1, it is characterized in that, its preparation method is: take: Cortex Lycii 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, the Rhizoma Pinelliae 9 parts, Herba Lysionoti Pauciflori 10 parts, 12 parts, Herba Ephedrae, Herba Pteridis Multifidae 10 parts, Bulbus Fritillariae Ussuriensis 15 parts, Spica Prunellae 9 parts, Fructus Perillae 8 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of the medicine of chronic obstructive emphysema as claimed in claim 1, it is characterized in that, its preparation method is: take: Cortex Lycii 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, the Rhizoma Pinelliae 9 parts, Herba Lysionoti Pauciflori 10 parts, 12 parts, Herba Ephedrae, Herba Pteridis Multifidae 10 parts, Bulbus Fritillariae Ussuriensis 15 parts, Spica Prunellae 9 parts, Fructus Perillae 8 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of the medicine of chronic obstructive emphysema as claimed in claim 1, it is characterized in that, its preparation method is: take: Cortex Lycii 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, the Rhizoma Pinelliae 9 parts, Herba Lysionoti Pauciflori 10 parts, 12 parts, Herba Ephedrae, Herba Pteridis Multifidae 10 parts, Bulbus Fritillariae Ussuriensis 15 parts, Spica Prunellae 9 parts, Fructus Perillae 8 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510785616.9A CN105327097A (en) | 2015-11-16 | 2015-11-16 | Drug for treating chronic obstructive emphysema |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510785616.9A CN105327097A (en) | 2015-11-16 | 2015-11-16 | Drug for treating chronic obstructive emphysema |
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| Publication Number | Publication Date |
|---|---|
| CN105327097A true CN105327097A (en) | 2016-02-17 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510785616.9A Pending CN105327097A (en) | 2015-11-16 | 2015-11-16 | Drug for treating chronic obstructive emphysema |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103860896A (en) * | 2014-04-04 | 2014-06-18 | 刘作功 | Medicament for treating chronic obstructive emphysema |
| CN104857150A (en) * | 2015-06-13 | 2015-08-26 | 青岛辰达生物科技有限公司 | Traditional Chinese medicine preparation for treating chronic obstructive emphysema |
-
2015
- 2015-11-16 CN CN201510785616.9A patent/CN105327097A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103860896A (en) * | 2014-04-04 | 2014-06-18 | 刘作功 | Medicament for treating chronic obstructive emphysema |
| CN104857150A (en) * | 2015-06-13 | 2015-08-26 | 青岛辰达生物科技有限公司 | Traditional Chinese medicine preparation for treating chronic obstructive emphysema |
Non-Patent Citations (1)
| Title |
|---|
| 冷方南等: "《中国中成药优选（修订版）》", 31 January 2014, 人民军医出版社 * |
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