CN105311255A - Medicine for treating acne - Google Patents
Medicine for treating acne Download PDFInfo
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- CN105311255A CN105311255A CN201510837363.5A CN201510837363A CN105311255A CN 105311255 A CN105311255 A CN 105311255A CN 201510837363 A CN201510837363 A CN 201510837363A CN 105311255 A CN105311255 A CN 105311255A
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Abstract
The invention provides medicine for treating acne. The medicine is prepared from, by weight, 10-20 parts of garden burnet, 10-20 parts of dried rehmannia roots, 10-20 parts of felwort, 10-20 parts of Chinese violet, 5-10 parts of fructus evodiae, 5-10 parts of eclipta, 5-10 parts of magnolia flowers, 5-10 parts of saposhnicovia divaricata, 5-10 parts of common cnidium fruits, 5-10 parts of Chinese thorowax roots, 5-10 parts of asarum sieboldi mig, 3-8 parts of ephedra, 3-8 parts of safflower, 3-8 parts of red peony roots, 3-8 parts of dandelions, 3-8 parts of fructus kochiae, 3-8 parts of honeysuckle, 3-8 parts of scutellaria baicalensis, 1-5 parts of cortex phellodendri, 1-5 parts of mint, 1-5 parts of centipede, 0.5-1 part of long-noded pit viper, 0.1-0.5 part of croton and 5-10 parts of liquorice. Common Chinese herbal medicine is adopted as raw materials, the source is wide, the formulation is scientific and reasonable, all the ingredients achieve the synergistic effect, blood circulation can be enhanced, bacterium inhibition and inflammation elimination are achieved effectively, skin metabolism is promoted, the curative effect on acne is good, and the effect is achieved.
Description
Technical field
The present invention relates to a kind of medicine of Acne treatment, belong to technical field of Chinese medicines.
Background technology
Acne is that a kind of chronic inflammatory skin of pilosebaceous unit is sick, is mainly apt to occur in teenager, also can falls ill in all age group, and clinical manifestation is to be apt to occur in the pleomorphism skin lesion such as acne, pimple, pustule, tuberosity of face for feature.The medicine of present market Acne treatment is based on Western medicine, and these Western medicine have the shortcomings, particularly some antibiosis anti-inflammatory drugs such as price is high, side effect is large, easily bring drug resistance, affect the problems such as human endocrine.
Summary of the invention
The technical problem to be solved in the present invention is: the medicine providing a kind of Acne treatment, has the advantages such as low price, therapeutic effect is good, toxic and side effects is little.
For solving the problems of the technologies described above, the present invention by the following technical solutions:
The medicine of Acne treatment, obtained by the raw material of following weight parts: Radix Sanguisorbae 10 ~ 20 parts, 10 ~ 20 parts, the Radix Rehmanniae, Radix Gentianae 10 ~ 20 parts, Herba Violae 10 ~ 20 parts, Fructus Evodiae 5 ~ 10 parts, Herba Ecliptae 5 ~ 10 parts, Flos Magnoliae 5 ~ 10 parts, Radix Saposhnikoviae 5 ~ 10 parts, Fructus Cnidii 5 ~ 10 parts, Radix Bupleuri 5 ~ 10 parts, Herba Asari 5 ~ 10 parts, 3 ~ 8 parts, Herba Ephedrae, 3 ~ 8 parts, Flos Carthami, Radix Paeoniae Rubra 3 ~ 8 parts, Herba Taraxaci 3 ~ 8 parts, the Fructus Kochiae 3 ~ 8 parts, Flos Lonicerae 3 ~ 8 parts, Radix Scutellariae 3 ~ 8 parts, Cortex Phellodendri 1 ~ 5 part, Herba Menthae 1 ~ 5 part, Scolopendra 1 ~ 5 part, Agkistrodon 0.5 ~ 1 part, Fructus Crotonis 0.1 ~ 0.5 part, 5 ~ 10 parts, Radix Glycyrrhizae.
As preferably, provide a concrete formula here, the weight portion of described raw material is:
Radix Sanguisorbae 10 parts, 15 parts, the Radix Rehmanniae, Radix Gentianae 20 parts, Herba Violae 10 parts, Fructus Evodiae 8 parts, Herba Ecliptae 10 parts, Flos Magnoliae 5 parts, Radix Saposhnikoviae 8 parts, Fructus Cnidii 10 parts, Radix Bupleuri 5 parts, Herba Asari 8 parts, 8 parts, Herba Ephedrae, 3 parts, Flos Carthami, Radix Paeoniae Rubra 5 parts, Herba Taraxaci 8 parts, the Fructus Kochiae 3 parts, Flos Lonicerae 5 parts, Radix Scutellariae 8 parts, Cortex Phellodendri 1 part, Herba Menthae 3 parts, Scolopendra 5 parts, Agkistrodon 0.5 part, Fructus Crotonis 0.3 part, 10 parts, Radix Glycyrrhizae.
As preferably, provide second concrete formula here, the weight portion of described raw material is:
Radix Sanguisorbae 15 parts, 20 parts, the Radix Rehmanniae, Radix Gentianae 10 parts, Herba Violae 15 parts, Fructus Evodiae 10 parts, Herba Ecliptae 5 parts, Flos Magnoliae 8 parts, Radix Saposhnikoviae 10 parts, Fructus Cnidii 5 parts, Radix Bupleuri 8 parts, Herba Asari 10 parts, 3 parts, Herba Ephedrae, 5 parts, Flos Carthami, Radix Paeoniae Rubra 8 parts, Herba Taraxaci 3 parts, the Fructus Kochiae 5 parts, Flos Lonicerae 8 parts, Radix Scutellariae 3 parts, Cortex Phellodendri 3 parts, Herba Menthae 5 parts, Scolopendra 1 part, Agkistrodon 0.8 part, Fructus Crotonis 0.5 part, 5 parts, Radix Glycyrrhizae.
As preferably, provide the 3rd concrete formula here, the weight portion of described raw material is:
Radix Sanguisorbae 20 parts, 10 parts, the Radix Rehmanniae, Radix Gentianae 15 parts, Herba Violae 20 parts, Fructus Evodiae 5 parts, Herba Ecliptae 8 parts, Flos Magnoliae 10 parts, Radix Saposhnikoviae 5 parts, Fructus Cnidii 8 parts, Radix Bupleuri 10 parts, Herba Asari 5 parts, 5 parts, Herba Ephedrae, 8 parts, Flos Carthami, Radix Paeoniae Rubra 3 parts, Herba Taraxaci 5 parts, the Fructus Kochiae 8 parts, Flos Lonicerae 3 parts, Radix Scutellariae 5 parts, Cortex Phellodendri 5 parts, Herba Menthae 1 part, Scolopendra 3 parts, Agkistrodon 1 part, Fructus Crotonis 0.1 part, 8 parts, Radix Glycyrrhizae.
The present invention also provides the preparation method of said medicine, its step the following is: by Scolopendra, Agkistrodon, after Fructus Crotonis and Radix Glycyrrhizae co-grinding, be first alcohol-pickled 1 ~ 3 hour of 30% ~ 60% by volumetric concentration, taking-up water rinses, be placed in the water that it soaks front weight 3 ~ 10 times, after being heated to boiling, decoct 0.5 ~ 1 hour under slight boiling condition, filter, filtrate is concentrated into 30% ~ 40% of its volume, add the modified starch of concentrated solution weight 1% ~ 3%, after spraying dry, by the dried powder that obtains and all the other raw material co-grinding to 40 ~ 100 orders, namely this medicine is obtained.
The using method of this medicine is: added by medicine in the hot water of its weight 2 ~ 3 times, and after stirring, uniform application is in affected part, and dosage, for be no more than 10 grams at every turn, uses 2 times for one day.
The invention has the beneficial effects as follows: raw material of the present invention is conventional Chinese herbal medicine, wide material sources, low price; Pharmaceutical formulation is scientific and reasonable, synergism between each component, can strengthen blood circulation, effectively inhibiting bacteria and diminishing inflammation, promote skin metabolism; Through the use of clinical 100 patients, the effective percentage in 3 weeks reaches 91%, and cure rate reaches 80%, and does not find toxic and side effects case, and to the good effect of acne, take effect fruit.
Detailed description of the invention
Further illustrate the present invention by the following examples, but the invention is not restricted to these embodiments.
Embodiment 1
The medicine of Acne treatment, is obtained by the raw material of following weight parts: Radix Sanguisorbae 10 parts, 15 parts, the Radix Rehmanniae, Radix Gentianae 20 parts, Herba Violae 10 parts, Fructus Evodiae 8 parts, Herba Ecliptae 10 parts, Flos Magnoliae 5 parts, Radix Saposhnikoviae 8 parts, Fructus Cnidii 10 parts, Radix Bupleuri 5 parts, Herba Asari 8 parts, 8 parts, Herba Ephedrae, 3 parts, Flos Carthami, Radix Paeoniae Rubra 5 parts, Herba Taraxaci 8 parts, the Fructus Kochiae 3 parts, Flos Lonicerae 5 parts, Radix Scutellariae 8 parts, Cortex Phellodendri 1 part, Herba Menthae 3 parts, Scolopendra 5 parts, Agkistrodon 0.5 part, Fructus Crotonis 0.3 part, 10 parts, Radix Glycyrrhizae.
The preparation method of medicine is: after Scolopendra, Agkistrodon, Fructus Crotonis and Radix Glycyrrhizae co-grinding, be first alcohol-pickled 2 hours of 30% by volumetric concentration, take out use water to rinse, be placed in the water that it soaks front weight 10 times, after being heated to boiling, decoct 0.5 hour under slight boiling condition, filter, filtrate is concentrated into 35% of its volume, adds the modified starch of concentrated solution weight 3%, after spraying dry, by dried powder and all the other raw material co-grinding to 40 orders of obtaining.
Embodiment 2
The medicine of Acne treatment, is obtained by the raw material of following weight parts: Radix Sanguisorbae 15 parts, 20 parts, the Radix Rehmanniae, Radix Gentianae 10 parts, Herba Violae 15 parts, Fructus Evodiae 10 parts, Herba Ecliptae 5 parts, Flos Magnoliae 8 parts, Radix Saposhnikoviae 10 parts, Fructus Cnidii 5 parts, Radix Bupleuri 8 parts, Herba Asari 10 parts, 3 parts, Herba Ephedrae, 5 parts, Flos Carthami, Radix Paeoniae Rubra 8 parts, Herba Taraxaci 3 parts, the Fructus Kochiae 5 parts, Flos Lonicerae 8 parts, Radix Scutellariae 3 parts, Cortex Phellodendri 3 parts, Herba Menthae 5 parts, Scolopendra 1 part, Agkistrodon 0.8 part, Fructus Crotonis 0.5 part, 5 parts, Radix Glycyrrhizae.
The preparation method of medicine is: after Scolopendra, Agkistrodon, Fructus Crotonis and Radix Glycyrrhizae co-grinding, be first alcohol-pickled 3 hours of 40% by volumetric concentration, take out use water to rinse, be placed in the water that it soaks front weight 3 times, after being heated to boiling, decoct 0.8 hour under slight boiling condition, filter, filtrate is concentrated into 40% of its volume, adds the modified starch of concentrated solution weight 1%, after spraying dry, by dried powder and all the other raw material co-grinding to 100 orders of obtaining.
Embodiment 3
The medicine of Acne treatment, is obtained by the raw material of following weight parts: Radix Sanguisorbae 20 parts, 10 parts, the Radix Rehmanniae, Radix Gentianae 15 parts, Herba Violae 20 parts, Fructus Evodiae 5 parts, Herba Ecliptae 8 parts, Flos Magnoliae 10 parts, Radix Saposhnikoviae 5 parts, Fructus Cnidii 8 parts, Radix Bupleuri 10 parts, Herba Asari 5 parts, 5 parts, Herba Ephedrae, 8 parts, Flos Carthami, Radix Paeoniae Rubra 3 parts, Herba Taraxaci 5 parts, the Fructus Kochiae 8 parts, Flos Lonicerae 3 parts, Radix Scutellariae 5 parts, Cortex Phellodendri 5 parts, Herba Menthae 1 part, Scolopendra 3 parts, Agkistrodon 1 part, Fructus Crotonis 0.1 part, 8 parts, Radix Glycyrrhizae.
The preparation method of medicine is: after Scolopendra, Agkistrodon, Fructus Crotonis and Radix Glycyrrhizae co-grinding, be first alcohol-pickled 1 hour of 60% by volumetric concentration, take out use water to rinse, be placed in the water that it soaks front weight 8 times, after being heated to boiling, decoct 1 hour under slight boiling condition, filter, filtrate is concentrated into 30% of its volume, adds the modified starch of concentrated solution weight 2%, after spraying dry, by dried powder and all the other raw material co-grinding to 60 orders of obtaining.
Toxicity test
Get ICR mice, before experiment, water 15h is can't help in fasting, is divided into 19 groups (the trial drug group of each embodiment 6 groups, matched groups 1 group).Each group of mouse tail vein administration, test 1 group and be all according to dosage respectively 500mg/kg, 1000mg/kg, 2000mg/kg, 5000mg/kg, 10000mg/kg, 20000mg/kg to test 6 groups of dosages, control group mice gives same volume distilled water.Examine and record administration at once to toxic reaction and the death condition of mice appearance in 7d; Bliss ' s method is adopted to calculate LD50.The following form of experimental result:
Group | mg/kg |
Embodiment 1 medicine | 5478.59 |
Embodiment 2 medicine | 5485.68 |
Embodiment 3 medicine | 5475.35 |
The LD50 of medicine is at more than 5475mg/kg as seen from the above table, and obviously the toxicity of this medicine is very low, in the rational scope of application, few to the toxic and side effects of human body.
Model case
Case 1: Wu, female, 28 years old, people from Nanning, certain Enterprise Staff, first visit on March 13 in 2015; Cover with small pox on the face and reach 8 years, after use medicine of the present invention is treated, the small pox of Jin Liangzhouhou face obviously reduces, and continues use rear recovery from illness in five weeks and does not recur again.
Case 2: what certain, man, 23 years old, people is thought in Guangxi, certain university student, first visit on February 24 in 2014; Thereafter back is long acne, treats 3 years without obvious curative effects by other treatment method, but after use medicine of the present invention carries out surrounding, namely fully recovers and do not recur.
Case 3: Cai, man, 18 years old, people is thought in Guangxi, certain Middle School Students, first visit on May 20 in 2015.Patient because of learning pressure, do not have enough sleep, there is acne its face and with it many places, and use medicine of the present invention after one week, acne obviously reduces, and use this Chinese medicine after three weeks, acne disappear and do not recur.
Claims (5)
1. the medicine of Acne treatment, it is characterized in that, obtained by the raw material of following weight parts: Radix Sanguisorbae 10 ~ 20 parts, 10 ~ 20 parts, the Radix Rehmanniae, Radix Gentianae 10 ~ 20 parts, Herba Violae 10 ~ 20 parts, Fructus Evodiae 5 ~ 10 parts, Herba Ecliptae 5 ~ 10 parts, Flos Magnoliae 5 ~ 10 parts, Radix Saposhnikoviae 5 ~ 10 parts, Fructus Cnidii 5 ~ 10 parts, Radix Bupleuri 5 ~ 10 parts, Herba Asari 5 ~ 10 parts, 3 ~ 8 parts, Herba Ephedrae, 3 ~ 8 parts, Flos Carthami, Radix Paeoniae Rubra 3 ~ 8 parts, Herba Taraxaci 3 ~ 8 parts, the Fructus Kochiae 3 ~ 8 parts, Flos Lonicerae 3 ~ 8 parts, Radix Scutellariae 3 ~ 8 parts, Cortex Phellodendri 1 ~ 5 part, Herba Menthae 1 ~ 5 part, Scolopendra 1 ~ 5 part, Agkistrodon 0.5 ~ 1 part, Fructus Crotonis 0.1 ~ 0.5 part, 5 ~ 10 parts, Radix Glycyrrhizae.
2. medicine according to claim 1, it is characterized in that, the weight portion of described raw material is: Radix Sanguisorbae 10 parts, 15 parts, the Radix Rehmanniae, Radix Gentianae 20 parts, Herba Violae 10 parts, Fructus Evodiae 8 parts, Herba Ecliptae 10 parts, Flos Magnoliae 5 parts, Radix Saposhnikoviae 8 parts, Fructus Cnidii 10 parts, Radix Bupleuri 5 parts, Herba Asari 8 parts, 8 parts, Herba Ephedrae, 3 parts, Flos Carthami, Radix Paeoniae Rubra 5 parts, Herba Taraxaci 8 parts, the Fructus Kochiae 3 parts, Flos Lonicerae 5 parts, Radix Scutellariae 8 parts, Cortex Phellodendri 1 part, Herba Menthae 3 parts, Scolopendra 5 parts, Agkistrodon 0.5 part, Fructus Crotonis 0.3 part, 10 parts, Radix Glycyrrhizae.
3. medicine according to claim 1, it is characterized in that, the weight portion of described raw material is: Radix Sanguisorbae 15 parts, 20 parts, the Radix Rehmanniae, Radix Gentianae 10 parts, Herba Violae 15 parts, Fructus Evodiae 10 parts, Herba Ecliptae 5 parts, Flos Magnoliae 8 parts, Radix Saposhnikoviae 10 parts, Fructus Cnidii 5 parts, Radix Bupleuri 8 parts, Herba Asari 10 parts, 3 parts, Herba Ephedrae, 5 parts, Flos Carthami, Radix Paeoniae Rubra 8 parts, Herba Taraxaci 3 parts, the Fructus Kochiae 5 parts, Flos Lonicerae 8 parts, Radix Scutellariae 3 parts, Cortex Phellodendri 3 parts, Herba Menthae 5 parts, Scolopendra 1 part, Agkistrodon 0.8 part, Fructus Crotonis 0.5 part, 5 parts, Radix Glycyrrhizae.
4. medicine according to claim 1, it is characterized in that, the weight portion of described raw material is: Radix Sanguisorbae 20 parts, 10 parts, the Radix Rehmanniae, Radix Gentianae 15 parts, Herba Violae 20 parts, Fructus Evodiae 5 parts, Herba Ecliptae 8 parts, Flos Magnoliae 10 parts, Radix Saposhnikoviae 5 parts, Fructus Cnidii 8 parts, Radix Bupleuri 10 parts, Herba Asari 5 parts, 5 parts, Herba Ephedrae, 8 parts, Flos Carthami, Radix Paeoniae Rubra 3 parts, Herba Taraxaci 5 parts, the Fructus Kochiae 8 parts, Flos Lonicerae 3 parts, Radix Scutellariae 5 parts, Cortex Phellodendri 5 parts, Herba Menthae 1 part, Scolopendra 3 parts, Agkistrodon 1 part, Fructus Crotonis 0.1 part, 8 parts, Radix Glycyrrhizae.
5. the medicine according to any one of Claims 1 to 4, it is characterized in that, the preparation method of medicine is: by Scolopendra, Agkistrodon, after Fructus Crotonis and Radix Glycyrrhizae co-grinding, be first alcohol-pickled 1 ~ 3 hour of 30% ~ 60% by volumetric concentration, taking-up water rinses, be placed in the water that it soaks front weight 3 ~ 10 times, after being heated to boiling, decoct 0.5 ~ 1 hour under slight boiling condition, filter, filtrate is concentrated into 30% ~ 40% of its volume, add the modified starch of concentrated solution weight 1% ~ 3%, after spraying dry, by the dried powder that obtains and all the other raw material co-grinding to 40 ~ 100 orders, namely this medicine is obtained.
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CN201510837363.5A CN105311255A (en) | 2015-11-27 | 2015-11-27 | Medicine for treating acne |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108324871A (en) * | 2018-03-31 | 2018-07-27 | 丁永奎 | A kind of Chinese medicine composition for treating acne |
Citations (4)
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CN101564529A (en) * | 2009-05-08 | 2009-10-28 | 贾淑芳 | Five-poisonous-creature Keyin capsule of traditional Chinese medicine for treating psoriasis |
CN101757539A (en) * | 2009-11-19 | 2010-06-30 | 王善海 | Traditional Chinese medicine for treating acne |
CN103751502A (en) * | 2014-02-20 | 2014-04-30 | 杨瑞海 | Traditional Chinese medicine for treating acne vulgaris |
CN105055821A (en) * | 2015-07-16 | 2015-11-18 | 陆开云 | Traditional Chinese medicine for treating acne and method for preparing traditional Chinese medicine |
-
2015
- 2015-11-27 CN CN201510837363.5A patent/CN105311255A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101564529A (en) * | 2009-05-08 | 2009-10-28 | 贾淑芳 | Five-poisonous-creature Keyin capsule of traditional Chinese medicine for treating psoriasis |
CN101757539A (en) * | 2009-11-19 | 2010-06-30 | 王善海 | Traditional Chinese medicine for treating acne |
CN103751502A (en) * | 2014-02-20 | 2014-04-30 | 杨瑞海 | Traditional Chinese medicine for treating acne vulgaris |
CN105055821A (en) * | 2015-07-16 | 2015-11-18 | 陆开云 | Traditional Chinese medicine for treating acne and method for preparing traditional Chinese medicine |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108324871A (en) * | 2018-03-31 | 2018-07-27 | 丁永奎 | A kind of Chinese medicine composition for treating acne |
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