CN105311185A - Medicine for treating chloasma - Google Patents

Medicine for treating chloasma Download PDF

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Publication number
CN105311185A
CN105311185A CN201510858361.4A CN201510858361A CN105311185A CN 105311185 A CN105311185 A CN 105311185A CN 201510858361 A CN201510858361 A CN 201510858361A CN 105311185 A CN105311185 A CN 105311185A
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parts
grams
medicine
chloasma
treatment
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CN201510858361.4A
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Chinese (zh)
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潘剑崎
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Individual
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Priority to CN201510858361.4A priority Critical patent/CN105311185A/en
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Abstract

The invention relates to a medicine for treating chloasma. The medicine is prepared from the following medicinal materials in parts by weight: 12 parts of tuber fleeceflower stem, 3 parts of yerbadetajo herb, 5 parts of American ginseng, 12 parts of mulberry fruit, 4 parts of all-grass of spinach, 9 parts of fortune's drynaria rhizome, 12 parts of gordon euryale seed, 8 parts of walnut seed, 10 parts of manyprickle acanthopanax root, 5 parts of finger citron, 5 parts of citron fruit and 8 parts of east Asian tree fern rhizome. A clinical experiment proves that the medicine provided by the invention can be used for treating chloasma safely and effectively.

Description

A kind of medicine for the treatment of chloasma
Technical field
The present invention relates to a kind of Chinese medicine, especially relate to a kind of medicine for the treatment of chloasma.
Background technology
Chloasma is a kind of acquired pigmentation dermatosis, shows as the yellowish-brown plaque-like pigmentation that two cheekbones and forehead position are butterfly distribution more, is more common in young and middle-aged women.Chloasma affects U.S. of the appearance of people, spreading result in and indirectly disfeature at face, and therefore most female patient loses beauty and glamour, and become self-doubt, depression feels oneself inferior, not only have heavy mental pressure, women's happiness is also subject to serious harm.
The ways and means of existing treatment chloasma mainly contains dietetic therapy, medication, naturopathy, but how undesirable therapeutic effect is, and wherein naturopathy is expensive and cure the symptoms, not the disease; Dietetic therapy onset is slow, needs to take good care of for a long time; Western medicine side effect is obvious.With rise and the prosperity of beauty culture, beauty treatment doctor also alleviates by every means or treats mottle, and Therapeutic Method mostly is orally taken for curing and external treatment eroding stripping.And strip off external treatment mostly be corrosion change skin treatment, easily scab trace and pigmentation, and easily recur.Mostly the beauty treatment freckle-removing cream of face external is to hide facial colour spot, also little to the therapeutic effect of mottle.So, find Therapeutic Method safely and effectively and seem particularly urgent.
At present the effective medicine of generally recognized as safe is still lacked at present for chloasma.
Involved by Chinese medicine of the present invention, the present Research of medical material is as follows:
Caulis Polygoni Multiflori
[source] this product is the dry rattan of polygonum multiflorum thunb PolygonummultiflorumThunb..
[function cures mainly] nourishing blood to tranquillize the mind, dispelling wind and removing obstruction in the collateral.
Herba Ecliptae
[source] is the herb of feverfew Eclipta prostrata.
[function cures mainly] removing heat from blood, hemostasis, the kidney invigorating, tonifying YIN.
Radix Panacis Quinquefolii
[source] this product is the dry root of Araliaceae Radix Panacis Quinquefolii PanaxquinquefoliumL..
[function cures mainly] boosting qi and nourishing yin, clearing away heat and promoting production of body fluid.
Fructus Mori
[source] this product is the dry fruit ear of moraceae plants Mulberry MorusalbaL..
[function cures mainly] to be enriched blood YIN nourishing, is promoted the production of body fluid and moisturize.
Herba Spinaciae
[source] Chenopodiaceae Herba Spinaciae SpinaciaoleraceaL., with all herbal medicine.
[function cures mainly] nourish yin and calm the liver, cough-relieving intestine moistening.
Rhizoma Drynariae
[source] this product is Plants of Polypodiaceae Mongolian oak Herba pteridii latiusculi Drynariafortunei(Kunze) dry rhizome of J.Sm..
[function cures mainly] the kidney invigorating, invigorates blood circulation, hemostasis.
Semen Euryales
[source] this product is the dry mature kernal of nymphaeaceae plant Gorgon euryale EuryaleferoxSalisb..
[function cures mainly] supplementing the kidney to control the nocturnal, spleen reinforcing antidiarrheal, damp eliminating leukorrhagia stopping.
Semen Juglandis
[source] this product is the dry mature seed of juglandaceae plant Semen Juglandis JuglansregiaL..
[function cures mainly] the kidney invigorating, warming the lung, intestine moistening.
Radix Et Caulis Acanthopanacis Senticosi
[source] this product is the drying of Araliaceae Radix Et Caulis Acanthopanacis Senticosi, root and rhizome or stem.
[function cures mainly] replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization.
Fructus Citri Sarcodactylis
[source] this product is the dry fruit of Rutaceae citrus plant Fructus Citri Sarcodactylis CitrusmedicaL.var.sarcodactylisSwingle.
[function cures mainly] liver-smoothing, qi-regulating, and stomach and alleviating pain.
Fructus Citri
[source] is rutaceae citron or fragrant round mature fruit.
[function cures mainly] liver-smoothing, qi-regulating, alleviating distention in middle-JIAO, reduces phlegm.
Rhizoma Cibotii
[source] this product is Dicksoniaceae plant Rhizoma Cibotii Cibotiumbarometz(L.) dry rhizome of J.Sm..
[function cures mainly] invigorating the liver and kidney, strong spinal column, wind-damp dispelling.
Summary of the invention
The present invention aims to provide a kind of medicine for the treatment of chloasma, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing chloasma.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of medicine for the treatment of chloasma, it is characterized in that, be prepared from by the medical material of following weight proportion: Caulis Polygoni Multiflori 12 parts, Herba Ecliptae 3 parts, Radix Panacis Quinquefolii 5 parts, 12 parts, Fructus Mori, Herba Spinaciae 4 parts, Rhizoma Drynariae 9 parts, Semen Euryales 12 parts, Semen Juglandis 8 parts, Radix Et Caulis Acanthopanacis Senticosi 10 parts, Fructus Citri Sarcodactylis 5 parts, Fructus Citri 5 parts, Rhizoma Cibotii 8 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects the outpatient service female patient of 89 routine chloasma altogether between in June ,-2015 in June, 2014, age 25-60 year, the course of disease 1 month-12 months.Be divided at random: treatment group 70 example, blank group 19 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2, diagnostic criteria
The diagnostic criteria of 2003 revised editions " clinical diagnosis of chloasma and curative effect determinate standard " is organized according to Dermatology Professional Committee of CAIM (Chinese Association Of Integrative Medicine) pigment disease:
(1) face is filbert to dark brown, well-defined patch, usually symmetrically property distribution, NIP performance and squama.
(2) without obvious subjective symptoms.
(3) women is multiple, after mainly occurring in adolescence.
(4) state of an illness can have seasonality, and the Chang Xiachong winter is light.
(5) pigmentation that Other diseases (as naevus fuscocaerules zygomaticus, riehl's melanosis and pigmentosa actinic lichen planus etc.) causes is got rid of.
3, test method
The oral the present invention of 3.1 treatment group according to the obtained capsule of specific embodiment 1, sooner or later each once, 10 days courses for the treatment of, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3.2 blank group oral placebo capsules, sooner or later respectively once, 10 days courses for the treatment of.
4, criterion of therapeutical effect and therapeutic outcome
4.1 criterion of therapeutical effect
Formulate with reference to " clinical disease diagnosis is according to curing improvement standard ".
Recovery from illness: naked eyes to disappear > 90% depending on mottle area, and color disappears substantially;
Take a turn for the better: mottle area disappears > 30% and≤60%, and color change can be perceiveed;
Invalid: naked eyes depending on mottle area disappear≤30%, color change not obvious.
4.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
Group n Recovery from illness Take a turn for the better Invalid Total effective rate (%) Untoward reaction example
Treatment group 70 17(24.3%) 43(61.4%) 10(14.2%) 85.8% 0
Blank group 19 0(0.0%) 3(15.8%) 16(84.2%) 15.8% 0
Visible, the present invention adopts the formula of science and suitable proportioning, with enriching yin and nourishing kidney, in and QI and blood be principle for the treatment of, adopt between each medicine and cooperatively interact, synergism, made Chinese medicine can safe and effective treatment chloasma.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Caulis Polygoni Multiflori 12 grams, Herba Ecliptae 3 grams, Radix Panacis Quinquefolii 5 grams, 12 grams, Fructus Mori, Herba Spinaciae 4 grams, Rhizoma Drynariae 9 grams, Semen Euryales 12 grams, Semen Juglandis 8 grams, Radix Et Caulis Acanthopanacis Senticosi 10 grams, Fructus Citri Sarcodactylis 5 grams, Fructus Citri 5 grams, Rhizoma Cibotii 8 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of normal 1 day consumption must be met.
Be used for the treatment of chloasma.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take: Caulis Polygoni Multiflori 12 grams, Herba Ecliptae 3 grams, Radix Panacis Quinquefolii 5 grams, 12 grams, Fructus Mori, Herba Spinaciae 4 grams, Rhizoma Drynariae 9 grams, Semen Euryales 12 grams, Semen Juglandis 8 grams, Radix Et Caulis Acanthopanacis Senticosi 10 grams, Fructus Citri Sarcodactylis 5 grams, Fructus Citri 5 grams, Rhizoma Cibotii 8 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, the powder of normal 1 day consumption must be met.
Be used for the treatment of chloasma.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take: Caulis Polygoni Multiflori 12 grams, Herba Ecliptae 3 grams, Radix Panacis Quinquefolii 5 grams, 12 grams, Fructus Mori, Herba Spinaciae 4 grams, Rhizoma Drynariae 9 grams, Semen Euryales 12 grams, Semen Juglandis 8 grams, Radix Et Caulis Acanthopanacis Senticosi 10 grams, Fructus Citri Sarcodactylis 5 grams, Fructus Citri 5 grams, Rhizoma Cibotii 8 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, granulate according to this area common process, packaging, can obtain the granule meeting normal 1 day consumption.
Be used for the treatment of chloasma.Oral, every bu is taken for twice sooner or later.

Claims (1)

1. treat the medicine of chloasma for one kind, it is characterized in that, be prepared from by the medical material of following weight proportion: Caulis Polygoni Multiflori 12 parts, Herba Ecliptae 3 parts, Radix Panacis Quinquefolii 5 parts, 12 parts, Fructus Mori, Herba Spinaciae 4 parts, Rhizoma Drynariae 9 parts, Semen Euryales 12 parts, Semen Juglandis 8 parts, Radix Et Caulis Acanthopanacis Senticosi 10 parts, Fructus Citri Sarcodactylis 5 parts, Fructus Citri 5 parts, Rhizoma Cibotii 8 parts.
CN201510858361.4A 2015-11-30 2015-11-30 Medicine for treating chloasma Withdrawn CN105311185A (en)

Priority Applications (1)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101024017A (en) * 2007-03-26 2007-08-29 殷彬 Chinese medicine for treating chloasma
CN104042944A (en) * 2014-05-30 2014-09-17 青岛华仁技术孵化器有限公司 Medicinal preparation used for treating chloasma

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101024017A (en) * 2007-03-26 2007-08-29 殷彬 Chinese medicine for treating chloasma
CN104042944A (en) * 2014-05-30 2014-09-17 青岛华仁技术孵化器有限公司 Medicinal preparation used for treating chloasma

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
刘远坝等: "七草汤治疗黄褐斑110例", 《陕西中医》 *

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Application publication date: 20160210