CN105288196A - Traditional Chinese medicine composition for treating rectal cancer caused by damp heat and phlegm retention - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating rectal cancer caused by damp heat and phlegm retention. The traditional Chinese medicine composition is characterized by being prepared from the following herbs by weight: 9-12 parts of aurcularia mesenlerica Pers., 15-20 parts of cantonese speranskia, 10-15 parts of inonotus cuticularis (Bull.: Fr.) Karst., 25-30 parts of hericium erinaceus, 20-25 parts of herb of dindygulen peperomia, 30-35 parts of New Zealand spinach, 6-9 parts of shiitake, 12-15 parts of pilea peltata hance, 12-15 parts of calabash seed, 20-25 parts of cynanchum amplexicaule, 10-15 parts of epipactis mairei Schltr., 12-15 parts of herba eupatorii, 10-15 parts of caesalpinia bonduc (Linn.) Roxb., 6-9 parts of leaf of Chinese crinum and 6-9 parts of liquorice. The traditional Chinese medicine composition is efficient and good in treating effect, and has the advantage that recurrence is avoided within several years.

Description

A kind of Chinese medicine composition for the treatment of damp heat and phlegm retention rectal cancer

Technical field

The present invention relates to a kind of Chinese medicine, particularly a kind of Chinese medicine composition being used for the treatment of damp heat and phlegm retention rectal cancer.

Background technology

Cancer between rectal cancer refers to from pectinate line to proctosigmoid intersection is one of modal malignant tumor of digestive tract.Its pathogenic factor is divided into endogenous cause of ill and exopathogenic factor, and exopathogenic factor has cold visitor outside intestinal, or sitting wetland, or eating and drinking without temperance, and comfortable food is rich, pure wine savoury, or eats unclean product etc. by mistake; Endogenous cause of ill is due to depression of being worried, and taste are become estranged and caused toxic dampness and heat and pent up.The early stage many non-evident symptons of rectal cancer, easily out in the cold, along with the development of the course of disease, tumor increases, and ulcer or infection occurs, just there will be manifest symptom, occur bowl evacuation habit change, hemafecia, chronic intestinal obstruction, General Symptoms etc. time to a certain extent.At present, the main method for the treatment of rectal cancer has: chemotherapy, radiotherapy, operative treatment, Chinese traditional treatment etc.A large amount of clinical practice proves, centering end-stage patients carry out heavy dose of Radiotherapy chemotherapy, or again carries out chemotherapy to producing the patient of drug resistance can only to lead debilitant life more critically ill, accelerates death.Clinically usually can see, patient's cause of the death is not because cancer itself causes, but due to not caused by science, inappropriate lethal treatment.Chinese traditional treatment can make up operative treatment, radiotherapy, chemotherapeutical deficiency, can consolidation radiotherapy, chemotherapy effect, the toxic and side effects of chemicotherapy can be eliminated again, extend the life of patient.The rectal cancer that the traditional Chinese medical science causes according to different reason, carries out Coryza Treated by Syndrome Differentiation in conjunction with clinical practice, is divided into by primary disease: insufficiency of the spleen damp-heat type, damp heat and phlegm retention, spleen renal cold wet type.

Summary of the invention

Object of the present invention aims to provide a kind of Chinese medicine composition for the treatment of damp heat and phlegm retention rectal cancer, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing damp heat and phlegm retention rectal cancer.

For achieving the above object, the present invention by the following technical solutions: a kind of Chinese medicine composition for the treatment of damp heat and phlegm retention rectal cancer, is characterized in that being made up of the medical material of following weight proportion:

Felt lid Auricularia 9-12 part, Herba speranskiae cantonensis 15-20 part, conjunction tree bacterium 10-15 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 25-30 part, Herba Peperomiae Dindygulensis 20-25 part, Herba tetragoniae 30-35 part, Lentinus Edodes 6-9 part, back flower skin ulcer 12-15 part, Semen Lagenariae sicerariae 12-15 part, Radix Cynanchi Amplexicaulis 20-25 part, Lan Zhu join 10-15 part, mountain Herba Eupatorii 12-15 part, Folium Caesalpiniae Cristae 10-15 part, Folium Crini Sinici 6-9 part, Radix Glycyrrhizae 6-9 part.

Source and the function of medical material involved in formula cure mainly as follows:

Felt lid Auricularia [source] medical material Ji Yuan: be the sporophore of Auriculariaceae Mycophyta felt lid Auricularia.[nature and flavor] are sweet; Flat [function cures mainly] antitumor.Main malignant tumor.

Herba speranskiae cantonensis [source] medical material Ji Yuan: be the herb of euphorbia plant Guangdong speranskia tuberculata.[nature and flavor] are bitter; Flat [return through] lung; Liver; Large intestine channel [function cures mainly] wind-damp dispelling; The meridian dredging; Removing blood stasis with potent drugs pain relieving.Main air pain of dampness syndrome; Lump in the abdomen; Scrofula; Furuncle swelling toxin; Traumatic injury.

Close tree bacterium [source] medical material Ji Yuan: be the sporophore of the rare pin hole bacterium of On Polyporaceae.[nature and flavor] are sweet; Flat [function cures mainly] is pleasant; Benefit god; Dispel the wind; Antitumor.Main gastropathy; Leprosy; Tumor.

Hericium erinaceus (Bull. Ex Fr.) Pers. [source] medical material Ji Yuan: be the sporophore of hedgehog fungus section fungus Hericium erinaceus (Bull. Ex Fr.) Pers., Hydnum.[nature and flavor] are sweet; Flat [return through] enters spleen, stomach through [function cures mainly] strengthening the spleen and nourishing the stomach; Calm the nerves; Anticancer.Main body void is weak; Dyspepsia; Insomnia; Gastroduodenal ulcer; Chronic gastritis; Digestive tract tumor.

Herba Peperomiae Dindygulensis [source] medical material Ji Yuan: be the herb of Piperaceae plant Herba Peperomiae Dindygulensis.[nature and flavor] are pungent; Cool [return through] lung; Spleen; Liver; Kidney channel [function cures mainly] heat-clearing and toxic substances removing; Blood stasis-eliminating and stagnation-dissipating; Inducing diuresis to remove edema.Main lung-heat cough with asthma; Measles; Sore; Cancerous protuberance; Burn and scald; Traumatic injury; Oedema due to nephritis.

Herba tetragoniae [source] medical material Ji Yuan: be the herb of Aizoaceae plant Herba tetragoniae.[nature and flavor] are sweet; Micro-pungent; Property flat [return through] lung; Liver; Large intestine channel [function cures mainly] wind and heat dispersing; Removing toxic substances and promoting subsidence of swelling.The hot conjunctival congestion of main air; Treatment skin ulcer swells and ache; Intestinal is scorching; Septicemia; Tumor.

Lentinus Edodes [source] medical material Ji Yuan: be the sporophore of Bai Mo section fungus Lentinus Edodes.[nature and flavor] are sweet; Property is put down; Nontoxic [return through] liver; Stomach is through [function cures mainly] righting tonify deficiency; Spleen benefiting and stimulating the appetite; To dispel the wind rash; Phlegm-eliminiating and qi-regulating; Removing toxic substances; Anticancer.Main healthy energy is weak; God is tired weak; Indigestion and loss of appetite; Dyspepsia; Anemia; Rickets; Hypertension; Hyperlipemia; Chronic hepatitis; Night sweat; Incontinence of urine; Edema; Measles is sent out not smooth thoroughly; Urticaria; Poison mushroom is poisoning; Tumor.

Back flower skin ulcer [source] medical material Ji Yuan: be the herb of contrayerva shield leaf Rhizoma Belamcandae.[nature and flavor] are pungent; Light; [function cures mainly] cool in nature heat-clearing and toxic substances removing; To eliminate the phlegm blood stasis dispelling.Main lung-heat cough with asthma; Pulmonary tuberculosis chronic cough; Spitting of blood; Sore swollen toxin; Traumatic injury; Traumatic hemorrhage; Infantile malnutrition.

Semen Lagenariae sicerariae [source] medical material Ji Yuan: the seed of state calabash and plant base reed and calabash courd.[nature and flavor] sweet in the mouth; Property flat [function cures mainly] heat-clearing and toxic substances removing; Reducing swelling and alleviating pain.Main pneumonia; Intestinal carbuncle; Bud pain.

Radix Cynanchi Amplexicaulis [source] medical material Ji Yuan: be asclepiadaceae.[nature and flavor] bitter in the mouth; Pungent; Property flat [return through] lung; Spleen channel [function cures mainly] heat-clearing and toxic substances removing; Wind-damp dispelling; Promoting blood circulation and detumescence.Main air pain of dampness syndrome; Migraine; Lumbago; Menoxenia; Acute mastitis; Carbuncle furunculosis.

Lan Zhucan [source] the orchid family helleborine platymiscium E. mairei EpipactismaireiSchltr., is used as medicine with root stock and root.Spring and autumn excavates, and cleans, using fresh herb or dry.[nature and flavor] are bitter, flat.[function cures mainly] vital energy regualting and blood circulation-promoting, blood stasis dispelling detoxifies.For cough, chest pain, sore swollen toxin, traumatic injury.

Mountain Herba Eupatorii [source] medical material Ji Yuan: be the herb of the single Ye Peilan of feverfew.[nature and flavor] acrid in the mouth; Bitter; Property flat [function cures mainly] drive away summer heat and deliver; Removing dampness for regulating stomach; Vital energy regualting and blood circulation-promoting; Removing toxic substances.Main Sunstroke by every means wets; Fever and headache; The vexed abdominal distention of born of the same parents; Dyspepsia; Gastroenteritis; Sense stomach; Cough; Pharyngolaryngitis; Tonsillitis; Menoxenia; Traumatic injury; Carbuncle; Venom.

The leaf that Folium Caesalpiniae Cristae [source] is leguminous plant Folium Caesalpiniae Cristae.Summer gathers, and dries.[nature and flavor] are bitter, cool.[function cures mainly] stasis-dispelling and pain-killing, heat-clearing and toxic substances removing.Treating acute and chronic gastritis, gastric ulcer, carbuncle furuncle swells.

Folium Crini Sinici [source] medical material Ji Yuan: be the leaf of amrallid Bulbus et Radix Crini Sinici.[nature and flavor] are pungent; Bitter; Cool [function cures mainly] heat-clearing and toxic substances removing; Stasis-dispelling and pain-killing.Main herpes simplex toxic swelling; Lymphadenitis; Pharyngolaryngitis; Headache; Arthralgia pain is numb; Traumatic injury congestive edema; Fracture; Venom.

Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

In the process of tcm syndrome differentiation and treatment, we are usually in conjunction with the state of an illness of the further patient diagnosed such as digital rectal examination or microscopic examination of rectum.The clinical manifestation of damp heat and phlegm retention rectal cancer is abdominal pain and distension, and pain determines tenderness, and abdomen has enclosed mass, and vow that flatulence subtracts, just defecation with blood and pus mucus, or tenesmus, or loose stool is just thin, tongue is dark red, has ecchymosis, yellow and thin fur, wiry and frequent pulse.Cooperatively interact between each medicine in formula, synergism, the effect such as made Chinese medicine has heat-clearing and toxic substances removing, regulating QI to relieve pain, blood stasis dispelling attack long-pending, antitumor, can effectively treat damp heat and phlegm retention rectal cancer, over 4 years, by showing the use of 50 routine patients, effective percentage reaches 86%.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, physical data

Inventor have collected the out-patient of 100 routine damp heat and phlegm retention rectal cancer altogether between in April ,-2014 in May, 2010, the age be 20-60 year, be divided at random: treatment group 50 example, matched group 50 example.The data there was no significant differences such as two groups of ages, have comparability.

2, test method

2.1 matched groups take XIAOLIU WAN, and by specification is taken, and within 10 weeks, are 1 course for the treatment of.

The oral the present invention of 2.2 treatment group according to the obtained Chinese medicinal granule of specific embodiment 1, early, middle and late each once.The course for the treatment of is 10 weeks.

3, criterion of therapeutical effect and therapeutic outcome

3.1 criterions of therapeutical effect:

Cure: good through root value criterion wound healing, without complication.Observe 5 years without recurrence.Complete incidence graph: lump disappears, symptom takes a turn for the better, and maintains more than 1 month without metastasis.Partial rcsponse: mass reduction >=50%, symptom alleviates, and maintains more than 1 month.Invalid: symptom is without improvement or tumor progression.

3.2 treatment statistical results are in table 1.

Table 1 liang group comparitive study

As can be seen here, the medicine adopting prescription of the present invention obtained can safe and effective treatment damp heat and phlegm retention rectal cancer.

Detailed description of the invention

Below in conjunction with the concrete example implemented, further detailed description is done to the present invention.

Specific embodiment 1

Take 9 grams, felt lid Auricularia, Herba speranskiae cantonensis 15 grams, close tree bacterium 10 grams, Hericium erinaceus (Bull. Ex Fr.) Pers. 25 grams, Herba Peperomiae Dindygulensis 20 grams, Herba tetragoniae 30 grams, 6 grams, Lentinus Edodes, back flower skin ulcer 12 grams, Semen Lagenariae sicerariae 12 grams, Radix Cynanchi Amplexicaulis 20 grams, Lan Zhu join 10 grams, mountain Herba Eupatorii 12 grams, Folium Caesalpiniae Cristae 10 grams, Folium Crini Sinici 6 grams, 6 grams, Radix Glycyrrhizae.Above various medical material grinding is become end, then uses conventional method " whole part " to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 10 grams, airtight, preserve in shady and cool, dry place.

Be used for the treatment of damp heat and phlegm retention rectal cancer.Oral, early, middle and late three one after each meals of every bu.

Specific embodiment 2

Take 10 grams, felt lid Auricularia, Herba speranskiae cantonensis 18 grams, close tree bacterium 12 grams, Hericium erinaceus (Bull. Ex Fr.) Pers. 28 grams, Herba Peperomiae Dindygulensis 22 grams, Herba tetragoniae 32 grams, 8 grams, Lentinus Edodes, back flower skin ulcer 13 grams, Semen Lagenariae sicerariae 13 grams, Radix Cynanchi Amplexicaulis 22 grams, Lan Zhu join 13 grams, mountain Herba Eupatorii 14 grams, Folium Caesalpiniae Cristae 12 grams, Folium Crini Sinici 8 grams, 8 grams, Radix Glycyrrhizae.Above various medical material grinding is become end, then uses conventional method " whole part " to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 10 grams, airtight, preserve in shady and cool, dry place.

Be used for the treatment of damp heat and phlegm retention rectal cancer.Oral, early, middle and late three one after each meals of every bu.

Specific embodiment 3

Take 12 grams, felt lid Auricularia, Herba speranskiae cantonensis 20 grams, close tree bacterium 15 grams, Hericium erinaceus (Bull. Ex Fr.) Pers. 30 grams, Herba Peperomiae Dindygulensis 25 grams, Herba tetragoniae 35 grams, 9 grams, Lentinus Edodes, back flower skin ulcer 15 grams, Semen Lagenariae sicerariae 15 grams, Radix Cynanchi Amplexicaulis 25 grams, Lan Zhu join 15 grams, mountain Herba Eupatorii 15 grams, Folium Caesalpiniae Cristae 15 grams, Folium Crini Sinici 9 grams, 9 grams, Radix Glycyrrhizae.Above various medical material grinding is become end, then uses conventional method " whole part " to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 10 grams, airtight, preserve in shady and cool, dry place.

Be used for the treatment of damp heat and phlegm retention rectal cancer.Oral, early, middle and late three one after each meals of every bu.

Claims (1)

1. treat a Chinese medicine composition for damp heat and phlegm retention rectal cancer, it is characterized in that being made up of the medical material of following weight proportion:

Felt lid Auricularia 9-12 part, Herba speranskiae cantonensis 15-20 part, conjunction tree bacterium 10-15 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 25-30 part, Herba Peperomiae Dindygulensis 20-25 part, Herba tetragoniae 30-35 part, Lentinus Edodes 6-9 part, back flower skin ulcer 12-15 part, Semen Lagenariae sicerariae 12-15 part, Radix Cynanchi Amplexicaulis 20-25 part, Lan Zhu join 10-15 part, mountain Herba Eupatorii 12-15 part, Folium Caesalpiniae Cristae 10-15 part, Folium Crini Sinici 6-9 part, Radix Glycyrrhizae 6-9 part.