CN105287722A - Danshen root-Jerusalem artichoke polysaccharide tablet - Google Patents
Danshen root-Jerusalem artichoke polysaccharide tablet Download PDFInfo
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- CN105287722A CN105287722A CN201510531115.8A CN201510531115A CN105287722A CN 105287722 A CN105287722 A CN 105287722A CN 201510531115 A CN201510531115 A CN 201510531115A CN 105287722 A CN105287722 A CN 105287722A
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- jerusalem artichoke
- radix salviae
- salviae miltiorrhizae
- artichoke polysaccharide
- danshen
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Abstract
The invention relates to a Danshen root-Jerusalem artichoke polysaccharide tablet and belongs to the technical field of healthcare food. The Danshen root-Jerusalem artichoke polysaccharide tablet is mainly prepared from Jerusalem artichoke polysaccharide by being compounded by Danshen powder or Danshen extract, Danshen solution and the like according to the steps of grinding, crushing, sieving, granulating and tabletting. The Danshen root-Jerusalem artichoke polysaccharide tablet aims to promote blood circulation to remove blood stasis, clear away the heart-fire, relieve restlessness, protect myocardium, dilate blood vessels, resist atherosclerosis and thrombus, improve microcirculation, regulate tissue repair and regeneration and lower blood glucose and blood fat, is harmless to human bodies and is taken conveniently. The Danshen root-Jerusalem artichoke polysaccharide tablet is mainly characterized by comprising 50-70g of Jerusalem artichoke polysaccharide, 30-50g of Danshen root or Danshen extract, 30-60ml of Danshen solution, 5-7g of sodium carboxymethyl starch serving as a disintegrating agent, 0.1-0.2%(wt) of magnesium stearate serving as a lubricating agent and 10-45ml of PVPK30 ethanol solution 0.5-2.5%(wt) serving as a binding agent. The Danshen root-Jerusalem artichoke polysaccharide tablet is prepared according to the steps of (1) extraction and purification of the Jerusalem artichoke polysaccharide, (2) Danshen root extraction and solution preparation, (3) preparation of the Danshen root-Jerusalem artichoke polysaccharide tablet, and (4) ethanol waste liquor recovery.
Description
Technical field
The invention belongs to a kind of nutrient and healthcare products technology category, relate to and a kind of extract Jerusalem artichoke polysaccharide and purification by feverfew Jerusalem artichoke tuber, then with the Technology of Radix Salviae Miltiorrhizae extract and the mutually composite and obtained Radix Salviae Miltiorrhizae Jerusalem artichoke polysaccharide tablet of other adjuvant.
Background technology
China's Jerusalem Artichoke Resource enriches, and all there is production various places, go deep into developmental research Jerusalem artichoke and resource can be made high-valued, land resources utilization high efficiency.Jerusalem artichoke polysaccharide has been the nutritional supplement of food by multiple state approval in the world, as a kind of dietary fibre complex, is formally approved.And the active ingredient of Radix Salviae Miltiorrhizae has blood circulation promoting and blood stasis dispelling, clear away heart-fire relieving restlessness, the angina pectoris caused for coronary heart disease and malaise.The pharmacological action of Radix Salviae Miltiorrhizae is extremely extensive; comprise myocardial preservation, blood vessel dilating, atherosclerosis, antithrombotic, improve microcirculation, regulate tissue repair and the effect such as regeneration, anti-inflammation; recently there is further research to its mechanism of action, found that again it has the effect such as antitumor, antioxidation simultaneously.The present invention is for raw material with Jerusalem artichoke tuber, Jerusalem artichoke polysaccharide is obtained through extraction and purification, mutually composite with Radix Salviae Miltiorrhizae active ingredient extract by a certain percentage again, make with Jerusalem artichoke polysaccharide as main material can for the Radix Salviae Miltiorrhizae Jerusalem artichoke polysaccharide tablet of oral taking chewy, this product except there is tune blood glucose, blood fat reducing, outside the various health care functions such as antithrombotic, also have and produce without the three wastes, be easy to the features such as industrialization.
Summary of the invention
The present invention, by obtaining Jerusalem artichoke polysaccharide to the extraction of Jerusalem artichoke tuber, purification, then be suitable for compatible with Radix Salviae Miltiorrhizae powder or Radix Salviae Miltiorrhizae extract, has made and can supply oral Radix Salviae Miltiorrhizae Jerusalem artichoke polysaccharide tablet.Clearly proposing is the new health care of food preparation that is main material with Jerusalem artichoke polysaccharide, it is characterized in that containing Jerusalem artichoke polysaccharide 50-70%(wt), Radix Salviae Miltiorrhizae or Radix Salviae Miltiorrhizae extract 30-50%(wt).
The present invention is functional edible health care product, has and reduces blood glucose, blood fat, the multiple auxiliary effect such as antithrombotic.
Detailed description of the invention
example 1 ~ example 3
operating process
1). the preparation method of Jerusalem artichoke polysaccharide: Jerusalem artichoke tuber or the sheet of choosing Directly Dried in Shadow or low-temperature air-drying storage carry out pulverizing granulating or powder.Jerusalem artichoke powder after precise pulverizing or granule are at room temperature added to the water, and stir temperature rising reflux and obtain extracting solution 2 times, then through concentrated, purification, precipitate with ethanol, the operations such as rectification recovery ethanol residual liquid, obtained white Jerusalem artichoke polysaccharide powder.
2). Radix Salviae Miltiorrhizae active ingredient is extracted: the Radix Salviae Miltiorrhizae choosing Directly Dried in Shadow or low-temperature air-drying storage is pulverized.Radix Salviae Miltiorrhizae powder after precise pulverizing is at room temperature added to the water, and stirs intensification 70-85 DEG C backflow and obtains extracting solution 3 times, then through concentrating, purification, the operations such as precipitate with ethanol, obtained Radix Salviae Miltiorrhizae active ingredient extract and the transparent Radix Salviae Miltiorrhizae solution of brownish red.
3). the preparation method of Radix Salviae Miltiorrhizae Jerusalem artichoke polysaccharide tablet: get raw material in proportion and each mass fraction of adjuvant grinds respectively or pulverizes, cross 120 mesh sieves for subsequent use; With the equivalent interior addition that progressively increases, its powder is placed in mix homogeneously in mixer, then drips adhesive and brownish red Radix Salviae Miltiorrhizae clear solution by a certain percentage, make soft material; Soft material is placed in granulation machine mistake 16 mesh sieves and makes granule, dry under low temperature; By dried granule through 40 mesh sieve granulate, interpolation lubricant intrinsic pressure 200 in tablet machine.Product meets the standard preparation requirement of 2010 editions States Pharmacopoeia specifications after testing.
process control parameters
Raw material, adjuvant, recipe ratio:
Jerusalem artichoke Polysaccharide A 50-70g, Radix Salviae Miltiorrhizae or Radix Salviae Miltiorrhizae extract B30-50g, Radix Salviae Miltiorrhizae solution C 30-60ml, disintegrating agent is carboxymethyl starch sodium Q5-7g; Lubricant is that magnesium stearate accounts for gross mass K0.1-0.2%(wt); Adhesive is PVPK30 ethanol solution concentration 0.5-2.5%(wt), volume S10-45ml.
In the concrete numerical value of each parameter of raw materials proportioning of Radix Salviae Miltiorrhizae Jerusalem artichoke polysaccharide tablet refer to following table.
| Index name | Symbol | Unit | Example 1 | Example 2 | Example 3 |
| Jerusalem artichoke polysaccharide consumption | A | g | 50 | 60 | 70 |
| Radix Salviae Miltiorrhizae powder or Radix Salviae Miltiorrhizae extract consumption | B | g | 50 | 40 | 30 |
| Radix Salviae Miltiorrhizae solution usage | C | ml | 30 | 45 | 60 |
| Carboxymethyl starch sodium consumption | Q | g | 7 | 6 | 5 |
| Magnesium stearate consumption | K | （wt） % | 0.1 | 0.15 | 0.2 |
| Adhesive consumption | S | ml | 45 | 35 | 10 |
formulation principle:
Jerusalem artichoke polysaccharide--there is reduction blood glucose to promote that the decomposition of sugared part makes superfluous sugared part be converted into the effect of heat, improve body fat balance.
Radix Salviae Miltiorrhizae--strengthen myocardial contraction, improve cardiac function, do not increase myocardial oxygen consumption; Coronary artery dilating, increases myocardial flow; Expansion peripheral blood vessel, blood flow increases; Cerebral blood flow declines, antithrombus formation; Improve plasmin activity; Extend bleeding and cotting time; Anticoagulant, improves hemorheological properties, improves microcirculation; Promote reparation and the regeneration of tissue; Blood circulation promoting and blood stasis dispelling, local congestion alleviates, nourishing blood to tranquillize the mind.
Technical characteristic of the present invention is auxiliary liver and kidney tonifying, tonifying YANG bone and muscle strengthening, and adjust blood glucose, blood fat reducing has various health care functions.Containing any material beyond any medicine-food two-purpose article and Chinese medicine health care product, the exploitation of this product will centering old-aged diabetic and having a delicate constitution, and sub-health population brings benefit, is good green health good merchantable brand.
Claims (14)
1. the preparation method of Radix Salviae Miltiorrhizae Jerusalem artichoke polysaccharide tablet, is made up of following process and step:
The extraction and purification of Jerusalem artichoke polysaccharide: Jerusalem artichoke dry powder adds gauge water, adopts ultrasonic or water extraction method, and room temperature or temperature rising reflux extract polysaccharide, by filtration, concentrated, purification, precipitate with ethanol, and cold drying etc., obtain the Jerusalem artichoke polysaccharide powder of white.
2. the extraction of Radix Salviae Miltiorrhizae active ingredient: Radix Salviae Miltiorrhizae powder is at room temperature added to the water, adopts ultrasonic or water extraction method, and room temperature or stirring intensification 70-85 DEG C backflow obtain extracting solution 3 times, again through concentrated, purification, the operations such as precipitate with ethanol, obtained Radix Salviae Miltiorrhizae active ingredient extract and the transparent Radix Salviae Miltiorrhizae solution of brownish red.
3. the preparation of Radix Salviae Miltiorrhizae Jerusalem artichoke polysaccharide tablet: be by integration of edible and medicinal herbs material and Chinese medicine health-care material Jerusalem artichoke polysaccharide, Radix Salviae Miltiorrhizae powder or Radix Salviae Miltiorrhizae extract, the raw material compositions such as Radix Salviae Miltiorrhizae solution.
4. there is the multi-efficiencies such as protection cardiac muscle, blood vessel dilating, atherosclerosis, antithrombotic, reduction blood glucose, Adjust-blood lipid, be characterised in that containing Jerusalem artichoke polysaccharide 50-70%(wt), Radix Salviae Miltiorrhizae powder or Radix Salviae Miltiorrhizae extract 30-50%(wt).
5. raw material, ratio of adjuvant: Jerusalem artichoke polysaccharide 50-70g, Radix Salviae Miltiorrhizae powder or Radix Salviae Miltiorrhizae extract 30-50g, Radix Salviae Miltiorrhizae solution 30-60ml.
6. disintegrating agent carboxymethyl base Starch Sodium 5-7g; Magnesium stearate lubricant accounts for gross mass 0.1-0.2%(wt); Adhesive PVPK30 ethanol solution concentration 0.5-2.5%(wt), volume 10-45ml.
7. preparation method: get raw material in proportion, ground 120 mesh sieves are for subsequent use respectively for each mass fraction of adjuvant; With the equivalent interior addition that progressively increases, its powder is placed in mix homogeneously in mixer, then drips adhesive in proportion and Radix Salviae Miltiorrhizae solution makes soft material; Soft material is placed in granulation machine mistake 16 mesh sieves and makes granule, dry under low temperature; By granule after drying through 40 mesh sieve granulate, and add lubricant in tablet machine intrinsic pressure 200.
8. product meets the standard preparation requirement of 2010 editions States Pharmacopoeia specifications after testing.
9. the preparation method of Radix Salviae Miltiorrhizae Jerusalem artichoke polysaccharide tablet according to claim 1, Jerusalem artichoke polysaccharide can adopt ultrasonic or water extracting method, after filtration, concentrated, purification, the technical processs such as precipitate with ethanol, obtained Jerusalem artichoke polysaccharide white powder.
10. the preparation method of Radix Salviae Miltiorrhizae Jerusalem artichoke polysaccharide tablet according to claim 1, Radix Salviae Miltiorrhizae extract and Radix Salviae Miltiorrhizae solution can adopt ultrasonic or water extraction to obtain through extraction, purification, concentrated, precipitate with ethanol.
The preparation method of 11. Radix Salviae Miltiorrhizae Jerusalem artichoke polysaccharide tablet according to claim 1; Jerusalem artichoke polysaccharide powder can with proper auxiliary materials Radix Salviae Miltiorrhizae powder or Radix Salviae Miltiorrhizae extract; Radix Salviae Miltiorrhizae solution is compatible; obtained can have auxiliary protection cardiac muscle for oral taking chewy; blood vessel dilating; regulate blood glucose, the tablet of the multi-efficiencies such as blood fat reducing.
The preparation method of 12. Radix Salviae Miltiorrhizae Jerusalem artichoke polysaccharide tablet according to claim 1, is characterized in that Jerusalem artichoke polyoses content 50-70%(wt), Radix Salviae Miltiorrhizae or extract are containing 30-50%(wt).
The nontoxic taking convenience of 13. this product, not containing the article beyond medicine-food two-purpose or Chinese medicine health care product, meets Chinese food health care requirement, can be used as green health product for the sub-health population such as diabetes, heart disease.
14. its advantages are that manufacture process is without the three wastes, is suitable for suitability for industrialized production.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201510531115.8A CN105287722A (en) | 2015-08-27 | 2015-08-27 | Danshen root-Jerusalem artichoke polysaccharide tablet |
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| CN201510531115.8A CN105287722A (en) | 2015-08-27 | 2015-08-27 | Danshen root-Jerusalem artichoke polysaccharide tablet |
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| CN105287722A true CN105287722A (en) | 2016-02-03 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107056959A (en) * | 2017-02-15 | 2017-08-18 | 周长征 | Jerusalem artichoke moderate resistance HSV 1, the composition of RSV, EV 71 and preparation |
| CN107624943A (en) * | 2017-11-08 | 2018-01-26 | 深圳瑞德源健康科技有限公司 | A kind of jerusalem artichoke pressed candy and preparation method thereof |
| CN109924334A (en) * | 2017-12-19 | 2019-06-25 | 王金民 | It is a kind of can bidirectional modulation blood glucose Jerusalem artichoke candy and its specialized package |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104522460A (en) * | 2014-11-27 | 2015-04-22 | 高铭鸿 | Jerusalem artichoke polysaccharide tablets beneficial for brain |
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2015
- 2015-08-27 CN CN201510531115.8A patent/CN105287722A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104522460A (en) * | 2014-11-27 | 2015-04-22 | 高铭鸿 | Jerusalem artichoke polysaccharide tablets beneficial for brain |
Non-Patent Citations (1)
| Title |
|---|
| 王强虎等: "《糖尿病绿色疗法》", 31 August 2014, 中国军医出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107056959A (en) * | 2017-02-15 | 2017-08-18 | 周长征 | Jerusalem artichoke moderate resistance HSV 1, the composition of RSV, EV 71 and preparation |
| CN107624943A (en) * | 2017-11-08 | 2018-01-26 | 深圳瑞德源健康科技有限公司 | A kind of jerusalem artichoke pressed candy and preparation method thereof |
| CN109924334A (en) * | 2017-12-19 | 2019-06-25 | 王金民 | It is a kind of can bidirectional modulation blood glucose Jerusalem artichoke candy and its specialized package |
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Application publication date: 20160203 |