CN105286016A - Casein hydrolysate peptide food for phenylalanine metabolic disorders - Google Patents
Casein hydrolysate peptide food for phenylalanine metabolic disorders Download PDFInfo
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- CN105286016A CN105286016A CN201510758833.9A CN201510758833A CN105286016A CN 105286016 A CN105286016 A CN 105286016A CN 201510758833 A CN201510758833 A CN 201510758833A CN 105286016 A CN105286016 A CN 105286016A
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- food
- phenylalanine
- casein hydrolysate
- acid
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a casein hydrolysate peptide food for phenylalanine metabolic disorders so as to solve the problems that the conventional diet of cannot meet the nutritional requirements of patients suffering from the phenylalanine metabolic disorders. According to the casein hydrolysate peptide food, casein hydrolysate peptides are used as raw materials, essential amino acids for human bodies are added, and besides, nutrients of coenzymes Q10, linoleic acid, a-linolenic acid, DHA, ARA, vitamins, biotin, minerals and the like are added, so that the food is prepared. According to the formula food disclosed by the invention, protein sources necessary daily for patients suffering from the phenylalanine metabolic disorders can be provided, the food is easy to absorb and utilize by human bodies, the vitamins and the minerals necessary for the human bodies can be complemented, and the nutritional status of the patients suffering from the phenylalanine metabolic disorders can be improved. An appropriate quantity of the coenzymes Q10 are added to the formula, so that cells in the human bodies can be activated, the immunity of the human bodies is improved, and antioxidation is strengthened. The food can delay aging and strengthen the vitality of the human bodies, and can also prevent cardiovascular system diseases.
Description
Technical field
The invention belongs to field of food, the casein hydrolysate peptides food of phenylalanine dysbolism disease.
Background technology
Phenylalanine dysbolism disease is a kind of hereditary disease, if father and mother carry pathogenic recessive gene, child just has 1/4th ill possibilities.Chinese Academy of Medical Sciences professor Huang Shangzhi claims, and China is to the examination coverage rate of phenylalanine dysbolism disease only 20%, and the global incidence of phenylalanine dysbolism disease is about 1/15000.The incomplete statistics data display that NGO (non-government organization) tissue is known, domestic about have 120,000 these type of infants, controlling colony about 20,000 people, and nearly 100,000 children or be on the verge of edge of paralysing.Current most area at home, the relief for phenylalanine dysbolism disease still belongs to blank, and this disease is also rarely known by the people.According to the sanitary work main points in 2013 that the Ministry of Public Health announces, China improves new system of rural cooperative medical and health care services by continuing, and improves new agriculture and closes
Financial aid standard, and include sick kinds the such as children's phenylalanine dysbolism disease in major disease medical security pilot scope.
The phenylalanine dysbolism of this disease system caused by PAH defect congenital in body.Phenylalanine is one of necessary amino acid of human body, after food intake, partly by protein in body synthesis is utilized, part becomes tyrosine through the role transformation of liver PAH, after be further converted to the important physiological activity materials such as dopamine, norepinephrine, adrenaline, melanin, the level of phenylalanine dysbolism disease infant liver PAH is only normal person's 1% or lower.Therefore phenylalanine can not be converted into tyrosine and extremely accumulate in vivo, and meanwhile, tyrosine, dopamine, norepinephrine, adrenaline, melanin etc. form obstacle, cause a series of nervous system damage.
Current phenylalanine dysbolism disease patient can carry out diet control by the intake of medicine or phenylalanine.Mainly carry out diet control with the intake by phenylalanine.Select gene treatment has been started abroad except the current absorption method except controlling phenylalanine.In addition, the phenylalanine lyases (PAL) in discovered in recent years plant does not need coenzyme just energy cracking phenylalanine, and this research is that disease treatment opens a new road.
Although also there are at present some special dietary seafoods for treatment phenylalanine dysbolism disease, all there is certain defect and problem, the nutritional labeling mainly needed for infant adds not comprehensively and not and specifically improves intelligible components.
Summary of the invention
The object of this invention is to provide a kind of casein hydrolysate peptides food of phenylalanine dysbolism disease, to solve the problem of phenylalanine dysbolism disease patient's nutritional need and conventional dietary deficiency thereof.
For reaching above-mentioned purpose, technical scheme of the present invention is as follows: a kind of casein hydrolysate peptides food of phenylalanine dysbolism disease, is formed by following proportion by weight by following ingredients:
Casein hydrolysate peptides 20.0 weight portion-40.0 weight portion, amino acid 25.0 weight portion-35.0 weight portion, linoleic acid 3.0 weight portion-4.0 weight portion, a-leukotrienes 0.3 weight portion-0.4 weight portion, Co-Q10 1.0 weight portion-3.0 weight portion, dietary fiber 10.0 weight portion-20.0 weight portion, vitamin 0.1 weight portion-1.0 weight portion, DHA (DHA) 0.02 weight portion-0.04 weight portion, ARA (arachidonic acid) 0.02 weight portion-0.04 weight portion and mineral matter 1.0 weight portion-2.0 weight portion.
Preferably, formed by following proportion by weight by following ingredients:
Casein hydrolysate peptides 30.0 weight portion, amino acid 30.0 weight portion, linoleic acid 3.0 weight portion, a-leukotrienes 0.4 weight portion, Co-Q10 2.0 weight portion, dietary fiber 15.0 weight portion, vitamin 0.46 weight portion, DHA (DHA) 0.03 weight portion, ARA (arachidonic acid) 0.03 weight portion and mineral matter 2.0 weight portion.
Preferably, casein hydrolysate peptides is that refer to and utilize existing biological enzyme hydrolysis technology, from skimmed milk power, separation and Extraction obtains not containing the range of hydrolysed peptides of phenylalanine.Described antioxidant Co-Q10 is the Co-Q10 in extracting in Qinghai-Tibet distinctive yak heart.
Preferably, amino acid is made up of the raw material of following proportion by weight: L-Leu 1-2 part, L-PROLINE 1-2 part, ILE 1-3 part, L-Lysine Acetate 2-4 part, L-threonine 2-4 part, L-Methionine 2-3 part, L-Trp 2-3 part, L-Histidine 1-2 part, TYR 1-2 part, Valine 1-2 part, ALANINE 1-2 part, Serine 1-2 part, glycine 1-2 part, L-arginine 1-2 part, ASPARTIC ACID 1-2 part, L-cysteine hydrochloride 1-2 part, Pidolidone 1-2 part.
Preferably, described dietary fiber is made up of the raw material of following proportion by weight: soluble dietary fiber 9.5-17.5 parts, insoluble dietary fiber 0.5-2.5 part.
Preferably, described vitamin is composed as follows: 3-Hydroxyretinol mg, vitamin E 30mg, vitamin C 0.1-0.3g, calciferol mg, Cobastab
10.04
-0.1g, Cobastab
20.45mg, Cobastab
60.85mg, Cobastab
122mg, nicotinic acid 5mg, folic acid lmg, pantothenic acid l0mg, choline 0.7mg, cigarette phthalein amine 5mg.
Preferably, described mineral matter is composed as follows: calcium 0.7-1.5g, potassium 0.05-0.4g, magnesium 0.05-0.4g, aluminium 20-50mg, iron 20-75mg, zinc 40-73mg, selenium 0.l-0.5mg, manganese l-9.6mg, chromium 0.0l-0.lmg, copper 0.1-0.4mg, molybdenum 0.01-0.1mg.
Above-mentioned various raw material mixes, and can keep powdery, or through granulation, makes powdery or granule state food.
Above-mentioned raw materials is mixed, stirs, through super-dry, make powdered food.Get 10g, after dissolving by about 200m1 warm water, directly drink.Every day 2 times.
The present invention for raw material, adds amino acid with skimmed milk power casein hydrolysate peptides, then is aided with the nutrients such as Co-Q10, linoleic acid, a-leukotrienes, DHA, ARA, cellulose, vitamin and mineral matter and is mixed with and forms.
Compatibility relationship of the present invention is as follows:
One, casein hydrolysate peptides used, refers to and utilizes biological enzyme hydrolysis technology, a kind of range of hydrolysed peptides of separation and Extraction from skimmed milk power, soluble in water, to sour, thermally-stabilised, directly can absorb without digestion, there is good bio-absorbable degree and bioavailability.Casein hydrolysate peptides, because of not containing phenylalanine, has various biological functional activity simultaneously, with its special meals diet as phenylalanine dysbolism disease patient, has the double effects supplementing the nutrients and regulate body function, has good market prospects.
Except trophic function, casein hydrolysate peptides also has a series of physiological active functions:
1. the attachment of anti-bacteria and virus
Receptor protein on range of hydrolysed peptides and host cell has similitude, has precedence over bacterium and virus combines, thus the breeding of anti-bacteria and virus, the pathogen such as anti-bacteria virus adhere to cell, protection body infecting from pathogen.
2. promote Bifidobacterium propagation
Bifidobacterium is intestinal beneficial bacterium, can suppress harmful bacterial growth, prevention enterogastric diseases.Even if the milk-derived range of hydrolysed peptides of people is also effective Bifidobacterium MF in the situation (500mg/L) that concentration is very low.
3. suppress gastro-intestinal secretion thing
Pepsin hydrolysis casein peptide obtains two peptide sections; wherein the molecular weight of larger peptide section is 7000-20000; can protease inhibition, trypsase, chymotrypsin is to the hydrolysis of albumen; thus protection Ruzhong immunoglobulin (Ig), lactoferrin and lysozyme isoreactivity albumen are not damaged, and arrive enteron aisle through stomach.
4. suppress influenza hemagglutinin
When influenza virus infects target cell, if target cells has containing sialic material, influenza virus is just combined with sialic acid, thus Cell protection is from infection.
5. in conjunction with cholera toxin and colitoxin
Casein hydrolysate peptides, as toxin nertralizer, can suppress the combination of the toxin such as cholera and acceptor.
6. other biological is active
Spleen lymphocyte participates in inflammatory reaction, suppresses the increment of splenocyte and then suppresses allergic reaction.Casein hydrolysis Toplink suppresses the generation causing the cytokinin of Multiplication of splenocyte, has the effect of immunity moderation system simultaneously.
Two, with the addition of Co-Q10 in formula makes formula be provided with other function:
1. antifatigue
Co-Q10 is natural and the cellular metabolism startup agent of cell self generation; there is the integrality of protection & restoration biofilm structure, the effect of stabilising membrane current potential; it is the nonspecific immunity strengthening agent of body; therefore fabulous antifatigue effect is demonstrated; Co-Q10 makes cell keep the state of good health; thus body is dynamic, full of vitality, plentifully mental.
2. anti-ageing
The immunologic function decline increased with the age is the result of free radical and radical reaction, Co-Q10 is used alone as a kind of powerful antioxidant or is combined the modification that can suppress microtubule system that acceptor on radical pair immunocyte is relevant with activity with Cell Differentiation to vitamin B6 (pyridoxol), strengthen immune system, delay senility.
3. anti-oxidant
The non-oxidizability of Co-Q10 makes it in atherosclerotic formation and development process, have certain inhibitory action.And its non-oxidizability makes that film is stable, metabolic cardiac stimulant and reverse the good actions such as Hypertensive disease, applies increasingly extensive in cardiovascular disease.
4. antitumor
Research shows, Co-Q10 has antitumor action, and clinical have certain curative effect for advanced metastatic cancer, and in prevention coronary heart disease, alleviate periodontitis, treatment duodenal ulcer and gastric ulcer, there is remarkable result enhancing body immunity function and allevating angina pectoris aspect.
5. cardioprotection
Coenzyme q-10 contributes to for cardiac muscle provides sufficient oxygen, and prevention sudden heart disease, especially in myocardial anoxia process, Co-Q10 plays key effect.
6. other effects
Co-Q10 also has many effects except above function, and as anti-hypertension, protection skin, safety in utilization is high.
Three, with the addition of linolenic and linoleic in formula makes formula be provided with other function.
1. leukotrienes forms the main component of human tissue cell, can synthesize in vivo, metabolism, is converted into body required vital activity factor D HA and EPA.
2. leukotrienes can effectively alleviate body disorders of lipid metabolism, improves immunity, increases the effects such as memory, antifatigue, raising eyesight, atherosclerosis.
3. leukotrienes can improve teen-age intelligence development.If infant, teenager lack leukotrienes, will have a strong impact on its normal intelligence grow, this point confirm by domestic and international scientist, and generally acknowledge by worldwide nutrition educational circles.
4. leukotrienes can act synergistically with the nutrient such as vitamin, mineral matter, protein, promotes effective absorption and the utilization of the nutrients such as vitamin, mineral matter, protein,
5. linoleic acid is as the precursor substance of some Physiological effect material (as prostaglandin);
6. linoleic acid can make cholesterol esterified, thus reduces the cholesterol levels in serum and liver, also has prevention effect to diabetes;
7. linoleic acid can suppress the formation of arterial thrombus, thus can prevent the generation of miocardial infarction
8. linoleic acid also plays an important role to maintenance body cell film function.
Four, with the addition of DHA and ARA in filling a prescription also makes formula be provided with other effect simultaneously.
1.DHA(docosapentaenoic acid) and ARA(arachidonic acid) be the requisite nutriment of brain and retinal development, provide certain nutrient to brain development.
2.ARA has important impact for the growth of human tissue organ, especially on the impact of brain and nervous system development, belongs to necessary fat acid at child ARA in period.
3.DHA is present in brain and retinal tissue in a large number, is the important feature composition of brain lipoprotein, accounts for 35% ~ 45% of brain fatty total content, account for 50% of retina phosphatide, to baby's intelligence and visual acuity most important.
This formula is according to " DRIs guide " and " food enrichment uses standard GB14880-2012 ", proportioning is carried out to the source of the nutrition fortifier of the casein hydrolysate peptides food formula of phenylalanine dysbolism disease and addition, simultaneously in conjunction with the physilogical characteristics of phenylalanine dysbolism disease patient, not containing phenylalanine in formula, add 7 kinds of other essential amino acids, dietary fiber, Co-Q10, DHA, ARA, the multiple nutritional components such as vitamin and mineral matter, meet the nutritional need of phenylalanine dysbolism disease patient.This food has and improves body nutrition condition, strengthens immunity of organisms, the auxiliary effect controlling phenylalanine dysbolism disease.
Detailed description of the invention
The following examples can further illustrate the present invention, but do not limit the present invention in any way.
Embodiment 1: the casein hydrolysate peptides food (powdery) preparing phenylalanine dysbolism disease.
(1) casein hydrolysate peptides 20g;
(2) amino acid 35g: wherein: L-Leu 1g, L-PROLINE 1g, ILE 3g, L-Lysine Acetate 4g, L-threonine 4g, L-Methionine 2g, L-Trp 3g, L-Histidine 2g, TYR 1g, Valine 1g, ALANINE 2g, Serine 2g, glycine 2g, L-arginine 2g, ASPARTIC ACID 2g, L-cysteine hydrochloride 2g, Pidolidone 2g;
(3) Co-Q10: 1g;
(4) unrighted acid: 3.4g, linoleic acid: 3.0g, a-leukotrienes: 0.3g;
(5) DHA(DHA): 0.02g;
(6) ARA(arachidonic acid): 0.02g;
(7) dietary fiber: 20g, wherein: soluble dietary fiber 17.5g, insoluble dietary fiber 2.5g;
(8) vitamin 0.2g: wherein: 3-Hydroxyretinol mg, vitamin E 30mg, vitamin C 0.1g, calciferol mg, Cobastab
10.04g, Cobastab
20.45mg, Cobastab
60.85mg, Cobastab
122mg, nicotinic acid 5mg, folic acid lmg, pantothenic acid l0mg, choline 0.7mg, cigarette phthalein amine 5mg;
(9) mineral matter (the interpolation form of mineral matter is the organic or inorganic compound of this mineral matter) 2.0g: wherein: calcium 1.5g, potassium 0.2g, magnesium 0.2g, aluminium 30mg, iron 20mg, zinc 40mg, selenium 0.lmg, manganese 9.6mg, chromium 0.lmg, copper 0.lmg, molybdenum 0.1mg.
Above-mentioned raw materials is mixed, stirs, through super-dry, make powdered food.Get 10g, after dissolving by about 200m1 warm water, directly drink.Every day 2 times.
Embodiment 2: the casein hydrolysate peptides food (graininess) preparing phenylalanine dysbolism disease.
(1) range of hydrolysed peptides: casein hydrolysate peptides 30g;
(2) amino acid 30g: wherein: L-Leu 2g, L-PROLINE 2g, ILE 2g, L-Lysine Acetate 3g, L-threonine 3g, L-Methionine 3g, L-Trp 2g, L-Histidine 1g, TYR 2g, Valine 2g, ALANINE 2g, Serine 1g, glycine 1g, L-arginine 1g, ASPARTIC ACID 1g, L-cysteine hydrochloride 1g, Pidolidone 1g;
(3) Co-Q10: 2g;
(4) unrighted acid: 3.4g, linoleic acid: 3.0g, a-leukotrienes: 0.4g
(5) DHA(DHA): 0.03g;
(6) ARA(arachidonic acid): 0.03g;
(7) dietary fiber: 15g, wherein: soluble dietary fiber 13.5g, insoluble dietary fiber 1.5g;
(8) vitamin 0.46g: wherein: 3-Hydroxyretinol mg, vitamin E 30mg, vitamin C 0.3g, calciferol mg, Cobastab
10.1g, Cobastab
20.45mg, Cobastab
60.85mg, Cobastab
122mg, nicotinic acid 5mg, folic acid lmg, pantothenic acid l0mg, choline 0.7mg, cigarette phthalein amine 5mg;
(9) (the interpolation form of mineral matter is the organic or inorganic compound of this mineral matter to mineral matter
): calcium 0.8g, potassium 0.4g, magnesium 0.4g, aluminium 20mg, iron 20mg, zinc 40mg, selenium 0.lmg, manganese 6mg, chromium 0.0lmg, copper 0.lmg, molybdenum 0.01mg.
Mixed by above-mentioned raw materials, stir, through super-dry, whole grain, makes graininess, gets 10g, after dissolving, directly drinks by about 150m1 warm water.Every day 2 times.The present embodiment products obtained therefrom performance is best.
Embodiment 3: the casein hydrolysate peptides food (powdery) preparing phenylalanine dysbolism disease.
(1) range of hydrolysed peptides: casein hydrolysate peptides 40g;
(2) amino acid 25g: wherein: L-Leu 2g, L-PROLINE 1g, ILE 1g, L-Lysine Acetate 2g, L-threonine 2g, L-Methionine 3g, L-Trp 2g, L-Histidine 1g, TYR 2g, Valine 2g, ALANINE 1g, Serine 1g, glycine 1g, L-arginine 1g, ASPARTIC ACID 1g, L-cysteine hydrochloride 1g, Pidolidone 1g;
(3) Co-Q10: 3g
(4) unrighted acid: 3.4g, linoleic acid: 4.0g, a-leukotrienes: 0.4g;
(5) DHA(DHA): 0.04g;
(6) ARA(arachidonic acid): 0.04g;
(7) dietary fiber: 10g, wherein: soluble dietary fiber 9.5g, insoluble dietary fiber 0.5g;
(8) dehydroretinol mg, vitamin E 30mg, vitamin C 0.3g, vitamin D lmg, Cobastab
10.1g, Cobastab
20.2mg, Cobastab
60.6mg, Cobastab
121mg, nicotinic acid 5mg, folic acid lmg, pantothenic acid l0mg, choline 0.5mg, cigarette phthalein amine 5mg;
(9) mineral matter (the interpolation form of mineral matter is the organic or inorganic compound of this mineral matter) 1.00g: calcium 0.7g, potassium 0.05g, magnesium 0.05g, aluminium 50mg, iron 75mg, zinc 73mg, selenium 0.5mg, manganese lmg, chromium 0.0lmg, copper 0.4mg, molybdenum 0.09mg.
Above-mentioned raw materials is mixed, stirs, through super-dry, make powdered food.Get 5g, after dissolving by about 100m1 warm water, directly drink.Every day 2 times.
Claims (7)
1. the casein hydrolysate peptides food of a phenylalanine dysbolism disease, it is characterized in that, formed by following proportion by weight by following ingredients: casein hydrolysate peptides 20.0 weight portion-40.0 weight portion, amino acid 25.0 weight portion-35.0 weight portion, linoleic acid 3.0 weight portion-4.0 weight portion, a-leukotrienes 0.3 weight portion-0.4 weight portion, Co-Q10 1.0 weight portion-3.0 weight portion, dietary fiber 10.0 weight portion-20.0 weight portion, vitamin 0.1 weight portion-1.0 weight portion, DHA 0.02 weight portion-0.04 weight portion, arachidonic acid 0.02 weight portion-0.04 weight portion and mineral matter 1.0 weight portion-2.0 weight portion.
2. the casein hydrolysate peptides food of phenylalanine dysbolism disease as claimed in claim 1, it is characterized in that, formed by following proportion by weight by following ingredients: casein hydrolysate peptides 30.0 weight portion, amino acid 30.0 weight portion, linoleic acid 3.0 weight portion, a-leukotrienes 0.4 weight portion, Co-Q10 2.0 weight portion, dietary fiber 15.0 weight portion, vitamin 0.46 weight portion, DHA 0.03 weight portion, arachidonic acid 0.03 weight portion and mineral matter 2.0 weight portion.
3. the casein hydrolysate peptides food of phenylalanine dysbolism disease as claimed in claim 1 or 2, is characterized in that: described casein hydrolysate peptides is that from skimmed milk power, separation and Extraction obtains not containing the range of hydrolysed peptides of phenylalanine.
4. the casein hydrolysate peptides food of phenylalanine dysbolism disease as claimed in claim 1, it is characterized in that, described amino acid is made up of the raw material of following proportion by weight: L-Leu 1-2 part, L-PROLINE 1-2 part, ILE 1-3 part, L-Lysine Acetate 2-4 part, L-threonine 2-4 part, L-Methionine 2-3 part, L-Trp 2-3 part, L-Histidine 1-2 part, TYR 1-2 part, Valine 1-2 part, ALANINE 1-2 part, Serine 1-2 part, glycine 1-2 part, L-arginine 1-2 part, ASPARTIC ACID 1-2 part, L-cysteine hydrochloride 1-2 part, Pidolidone 1-2 part.
5. the casein hydrolysate peptides food of phenylalanine dysbolism disease as claimed in claim 1, it is characterized in that, described dietary fiber is made up of the raw material of following proportion by weight: soluble dietary fiber 9.5-17.5 parts, insoluble dietary fiber 0.5-2.5 part.
6. the casein hydrolysate peptides food of phenylalanine dysbolism disease as claimed in claim 1, it is characterized in that, described vitamin is composed as follows: 3-Hydroxyretinol mg, vitamin E 30mg, vitamin C 0.1-0.3g, calciferol mg, Cobastab
10.04
-0.1g, Cobastab
20.45mg, Cobastab
60.85mg, Cobastab
122mg, nicotinic acid 5mg, folic acid lmg, pantothenic acid l0mg, choline 0.7mg, cigarette phthalein amine 5mg.
7. the casein hydrolysate peptides food of phenylalanine dysbolism disease as claimed in claim 1, it is characterized in that, described mineral matter is composed as follows: calcium 0.7-1.5g, potassium 0.05-0.4g, magnesium 0.05-0.4g, aluminium 20-50mg, iron 20-75mg, zinc 40-73mg, selenium 0.l-0.5mg, manganese l-9.6mg, chromium 0.0l-0.lmg, copper 0.1-0.4mg, molybdenum 0.01-0.1mg.
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04126051A (en) * | 1990-09-18 | 1992-04-27 | Snow Brand Milk Prod Co Ltd | Nutritional preparation for patient suffering from phenylketonuria |
JP2000342189A (en) * | 1999-06-02 | 2000-12-12 | Morinaga Milk Ind Co Ltd | Production of low phenylalamine peptide mixture |
CN103462003A (en) * | 2013-08-13 | 2013-12-25 | 甘肃华羚生物技术研究中心 | Meal food special for patient with phenylketonuria |
CN104367569A (en) * | 2014-11-06 | 2015-02-25 | 江苏隆力奇生物科技股份有限公司 | Nano coenzyme Q10 oral liquid |
-
2015
- 2015-11-10 CN CN201510758833.9A patent/CN105286016A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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JPH04126051A (en) * | 1990-09-18 | 1992-04-27 | Snow Brand Milk Prod Co Ltd | Nutritional preparation for patient suffering from phenylketonuria |
JP2000342189A (en) * | 1999-06-02 | 2000-12-12 | Morinaga Milk Ind Co Ltd | Production of low phenylalamine peptide mixture |
CN103462003A (en) * | 2013-08-13 | 2013-12-25 | 甘肃华羚生物技术研究中心 | Meal food special for patient with phenylketonuria |
CN104367569A (en) * | 2014-11-06 | 2015-02-25 | 江苏隆力奇生物科技股份有限公司 | Nano coenzyme Q10 oral liquid |
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