CN105284908A - Compound preparation containing pyrimidine nucleoside antibiotics - Google Patents

Compound preparation containing pyrimidine nucleoside antibiotics Download PDF

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Publication number
CN105284908A
CN105284908A CN201510894839.9A CN201510894839A CN105284908A CN 105284908 A CN105284908 A CN 105284908A CN 201510894839 A CN201510894839 A CN 201510894839A CN 105284908 A CN105284908 A CN 105284908A
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China
Prior art keywords
complex preparation
pyrimidine nucleoside
lentinan
antibiotic
ethanol
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Pending
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CN201510894839.9A
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Chinese (zh)
Inventor
张英
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Jinan Shunhao Biotechnology Co Ltd
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Jinan Shunhao Biotechnology Co Ltd
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Priority to CN201510894839.9A priority Critical patent/CN105284908A/en
Publication of CN105284908A publication Critical patent/CN105284908A/en
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Abstract

The invention relates to a compound preparation containing pyrimidine nucleoside antibiotics. The dosage form of the compound preparation is emulsion in water. The compound preparation comprises lentinan, plant activator proteins, pyrimidine nucleoside antibiotics, benzyl dimethyl phenol polyoxyethyl ether, ethanol, sodium alginate, glycerin, C8-10 fatty alcohols and deionized water. The compound preparation is a compound pesticide used for controlling powdery mildew of snake melons and has the advantages that after lentinan, the plant activator proteins and the pyrimidine nucleoside antibiotics are compounded, not only can the disease control effects be improved but also the dosage and use frequency of the chemical pesticide can be reduced; and after lentinan, the plant activator proteins and the pyrimidine nucleoside antibiotics are compounded, the compound preparation has obvious synergistic effects, has the effect of effectively reinforcing the functions of preventing and treating the powdery mildew of snake melons, takes effect quickly, has long duration, does not affect non-target crops and has obvious yield-increasing effects on the snake melons.

Description

Complex preparation containing antibiotic in pyrimidine nucleoside class
Technical field
The present invention relates to the complex preparation containing antibiotic in pyrimidine nucleoside class, being specially the aqueous emulsion for preventing and treating snake melon powdery mildew containing antibiotic in pyrimidine nucleoside class, belonging to pesticide field.
Background technology
Snake melon powdery mildew, fall ill from seedling stage, main harm blade, be secondly petiole and stem, fruit is seldom injured.Their early stage, there is white little mildew in face of blade and the back side, be many with leaf front, its backward surrounding is extended to the clear spot of white powder in flakes of blur margin, and time serious, whole blade face is covered with white powder.
Antibiotic in pyrimidine nucleoside class is a kind of efficient, broad spectrum biological disinfection agent, has prevention & protection and interior suction treatment double effects; Medicament can form the polymer protective film of one deck densification on plant and fruit surface, has strong suppression and inhibition to multiple pathogen; It is inner that therapeutic component arrives fruit by limb conduction, directly hinders the synthesis of pathogenic proteins matter, causes it dead.Antibiotic in pyrimidine nucleoside class protection is fine and close, and interior absorption is strong.
Lentinan is the effective active composition extracted from quality xianggu fruit body, is a kind of host immunity reinforcing agent, and lentinan has antiviral, antitumor, immunity moderation function and stimulates the functions such as interferon formation.Lentinan is the composition improving phyto-immunity, and the polysaccharide of its molecular weight more than 10,000 is main with β-1,3 glucan, containing a small amount of wood sugar and mannose.Lentinan is mainly used in field of medicaments the earliest, and that studies biopesticide along with people deepens continuously, and has at present and lentinan is used for pesticide field.
Plant activation protein is that a class of separation and Extraction from fungi has Promoting plant growth and improves the heat-stable protein exciton of its resistance.This molecular weight of albumen is 42kD, and isoelectric point is about that the current plant activation protein of 4.18. mainly screens from the fungies such as Alternariaspp, sheath blight fungus, Aspergillus flavus, botrytis, rice blast fungus, sickle-like bacteria, abstraction and purification obtains.Plant activation protein has biologically actives such as strengthening plant disease-resistant, insect protected, anti-adversity ability and Promoting plant growth.
Summary of the invention
The object of the present invention is to provide a kind of complex preparation containing antibiotic in pyrimidine nucleoside class, the formulation of complex preparation of the present invention is aqueous emulsion.The present invention has significant control efficiency to snake melon powdery mildew, and environmentally safe, and the lasting period is long, significantly increases the output of snake melon.
Complex preparation containing antibiotic in pyrimidine nucleoside class, is made up of following raw material:
Lentinan, plant activation protein, antibiotic in pyrimidine nucleoside class, benzyl dimethyl phenol polyoxyethyl ether, ethanol, sodium alginate, glycerine, C 8-10aliphatic alcohols and deionized water.
In above-mentioned complex preparation, each raw material components is by mass percentage:
Lentinan 0.01-0.1%, plant activation protein 0.1-1%, antibiotic in pyrimidine nucleoside class 2-5%, benzyl dimethyl phenol polyoxyethyl ether 5-10%, ethanol 3-8%, sodium alginate 0.03-0.05%, glycerine 3-8%, C 8-10aliphatic alcohols 0.3-0.5%, deionized water supply 100%.
Preferably, in described complex preparation, each raw material components is by mass percentage:
Lentinan 0.01-0.09%, plant activation protein 0.1-0.9%, antibiotic in pyrimidine nucleoside class 2.5-5%, benzyl dimethyl phenol polyoxyethyl ether 6-9%, ethanol 3-6%, sodium alginate 0.03-0.05%, glycerine 3-7%, C 8-10aliphatic alcohols 0.3-0.5%, deionized water supply 100%.
Preferably, in described complex preparation, each raw material components is by mass percentage:
Lentinan 0.02-0.08%, plant activation protein 0.2-0.8%, antibiotic in pyrimidine nucleoside class 2.5-4.5%, benzyl dimethyl phenol polyoxyethyl ether 6-9%, ethanol 3-6%, sodium alginate 0.03-0.05%, glycerine 3-7%, C 8-10aliphatic alcohols 0.3-0.5%, deionized water supply 100%.
Preferably, in described complex preparation, each raw material components is by mass percentage:
Lentinan 0.02-0.07%, plant activation protein 0.3-0.7%, antibiotic in pyrimidine nucleoside class 3-4.5%, benzyl dimethyl phenol polyoxyethyl ether 7-8%, ethanol 4-6%, sodium alginate 0.04-0.05%, glycerine 3-6%, C 8-10aliphatic alcohols 0.3-0.4%, deionized water supply 100%.
Preferred, in described complex preparation, each raw material components is by mass percentage:
Lentinan 0.045%, plant activation protein 0.455%, antibiotic in pyrimidine nucleoside class 3.5%, benzyl dimethyl phenol polyoxyethyl ether 8%, ethanol 5%, sodium alginate 0.05%, glycerine 5%, C 8-10aliphatic alcohols 0.4%, deionized water supply 100%.
When above-mentioned complex preparation is for preventing and treating snake melon powdery mildew, the usage amount of medicament is 10-20mL/ hectare, and preferred medicament usage amount is 12-18mL/ hectare, and preferred medicament usage amount is 14.5mL/ hectare.
The present invention compared with prior art has the following advantages:
The present invention can not only improve the control efficiency of disease, and chemical pesticide consumption and times for spraying can be reduced, after lentinan, plant activation protein and antibiotic in pyrimidine nucleoside class are composite, there is obvious synergistic effect, effectively enhance the effect of the prevention and therapy to snake melon powdery mildew, instant effect, lasting period is long, on non-Target crops without impact, and has obvious effect of increasing production to snake melon.
Embodiment
Further describe the present invention below in conjunction with specific embodiment, advantage and disadvantage of the present invention will be more clear along with description.But embodiment is only exemplary, does not form any restriction to scope of the present invention.It will be understood by those skilled in the art that and can modify to the details of technical solution of the present invention and form or replace down without departing from the spirit and scope of the present invention, but these amendments and replacement all fall within the scope of protection of the present invention.
The complex preparation of embodiment 1 containing antibiotic in pyrimidine nucleoside class
In described complex preparation, each raw material components is by mass percentage:
Lentinan 0.045%, plant activation protein 0.455%, antibiotic in pyrimidine nucleoside class 3.5%, benzyl dimethyl phenol polyoxyethyl ether 8%, ethanol 5%, sodium alginate 0.05%, glycerine 5%, C 8-10aliphatic alcohols 0.4%, deionized water supply 100%.
Be used for preventing and treating snake melon powdery mildew by the complex preparation that the embodiment of the present invention 1 obtains, the dispenser of snake melon powdery mildew their early stage, preparation dosage is 14.5mL/ hectare, and spray 1 time, after medicine, the control efficiency of 14 days is 96.9%.4% antibiotic in pyrimidine nucleoside class aqua presses 400 times of liquid spray pesticides 1 time, and after medicine, the control efficiency of 14 days is 88.6%.
The complex preparation of embodiment 2 containing antibiotic in pyrimidine nucleoside class
In described complex preparation, each raw material components is by mass percentage:
Lentinan 0.02%, plant activation protein 0.7%, antibiotic in pyrimidine nucleoside class 4%, benzyl dimethyl phenol polyoxyethyl ether 6%, ethanol 4%, sodium alginate 0.04%, glycerine 6%, C 8-10aliphatic alcohols 0.4%, deionized water supply 100%.
Be used for preventing and treating snake melon powdery mildew by the complex preparation that the embodiment of the present invention 2 obtains, the dispenser of snake melon powdery mildew their early stage, preparation dosage is 10mL/ hectare, and spray 1 time, after medicine, the control efficiency of 14 days is 96.1%.4% antibiotic in pyrimidine nucleoside class aqua presses 400 times of liquid spray pesticides 1 time, and after medicine, the control efficiency of 14 days is 88.6%.
The complex preparation of embodiment 3 containing antibiotic in pyrimidine nucleoside class
In described complex preparation, each raw material components is by mass percentage:
Lentinan 0.07%, plant activation protein 0.3%, antibiotic in pyrimidine nucleoside class 2.5%, benzyl dimethyl phenol polyoxyethyl ether 8%, ethanol 4%, sodium alginate 0.03%, glycerine 6%, C 8-10aliphatic alcohols 0.5%, deionized water supply 100%.
Be used for preventing and treating snake melon powdery mildew by the complex preparation that the embodiment of the present invention 3 obtains, the dispenser of snake melon powdery mildew their early stage, preparation dosage is 18mL/ hectare, and spray 1 time, after medicine, the control efficiency of 14 days is 95.0%.4% antibiotic in pyrimidine nucleoside class aqua presses 400 times of liquid spray pesticides 1 time, and after medicine, the control efficiency of 14 days is 88.6%.

Claims (10)

1. the complex preparation containing antibiotic in pyrimidine nucleoside class, it is characterized in that, the formulation of described complex preparation is aqueous emulsion, and described complex preparation is made up of following raw material:
Lentinan, plant activation protein, antibiotic in pyrimidine nucleoside class, benzyl dimethyl phenol polyoxyethyl ether, ethanol, sodium alginate, glycerine, C 8-10aliphatic alcohols and deionized water.
2. complex preparation according to claim 1, is characterized in that, in described complex preparation, each raw material components is by mass percentage:
Lentinan 0.01-0.1%, plant activation protein 0.1-1%, antibiotic in pyrimidine nucleoside class 2-5%, benzyl dimethyl phenol polyoxyethyl ether 5-10%, ethanol 3-8%, sodium alginate 0.03-0.05%, glycerine 3-8%, C 8-10aliphatic alcohols 0.3-0.5%, deionized water supply 100%.
3. complex preparation according to claim 2, is characterized in that, in described complex preparation, each raw material components is by mass percentage:
Lentinan 0.01-0.09%, plant activation protein 0.1-0.9%, antibiotic in pyrimidine nucleoside class 2.5-5%, benzyl dimethyl phenol polyoxyethyl ether 6-9%, ethanol 3-6%, sodium alginate 0.03-0.05%, glycerine 3-7%, C 8-10aliphatic alcohols 0.3-0.5%, deionized water supply 100%.
4. complex preparation according to claim 3, is characterized in that, in described complex preparation, each raw material components is by mass percentage:
Lentinan 0.02-0.08%, plant activation protein 0.2-0.8%, antibiotic in pyrimidine nucleoside class 2.5-4.5%, benzyl dimethyl phenol polyoxyethyl ether 6-9%, ethanol 3-6%, sodium alginate 0.03-0.05%, glycerine 3-7%, C 8-10aliphatic alcohols 0.3-0.5%, deionized water supply 100%.
5. complex preparation according to claim 4, is characterized in that, in described complex preparation, each raw material components is by mass percentage:
Lentinan 0.02-0.07%, plant activation protein 0.3-0.7%, antibiotic in pyrimidine nucleoside class 3-4.5%, benzyl dimethyl phenol polyoxyethyl ether 7-8%, ethanol 4-6%, sodium alginate 0.04-0.05%, glycerine 3-6%, C 8-10aliphatic alcohols 0.3-0.4%, deionized water supply 100%.
6. complex preparation according to claim 1, is characterized in that, in described complex preparation, each raw material components is by mass percentage:
Lentinan 0.045%, plant activation protein 0.455%, antibiotic in pyrimidine nucleoside class 3.5%, benzyl dimethyl phenol polyoxyethyl ether 8%, ethanol 5%, sodium alginate 0.05%, glycerine 5%, C 8-10aliphatic alcohols 0.4%, deionized water supply 100%.
7., when the complex preparation as described in any one of claim 1-6 is for preventing and treating snake melon powdery mildew, the usage amount of medicament is 10-20mL/ hectare.
8., when complex preparation according to claim 7 is for preventing and treating snake melon powdery mildew, the usage amount of medicament is 12-18mL/ hectare.
9., when complex preparation according to claim 8 is for preventing and treating snake melon powdery mildew, the usage amount of medicament is 14.5mL/ hectare.
10. the purposes of the complex preparation as described in claim 1-6 in control snake melon powdery mildew.
CN201510894839.9A 2015-12-08 2015-12-08 Compound preparation containing pyrimidine nucleoside antibiotics Pending CN105284908A (en)

Priority Applications (1)

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CN201510894839.9A CN105284908A (en) 2015-12-08 2015-12-08 Compound preparation containing pyrimidine nucleoside antibiotics

Publications (1)

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CN105284908A true CN105284908A (en) 2016-02-03

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103843826A (en) * 2012-12-04 2014-06-11 陕西汤普森生物科技有限公司 Fungicidal composition containing alternaria tenuissima-activated protein
CN104041524A (en) * 2014-06-25 2014-09-17 北京燕化永乐生物科技股份有限公司 Sterilization composition

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103843826A (en) * 2012-12-04 2014-06-11 陕西汤普森生物科技有限公司 Fungicidal composition containing alternaria tenuissima-activated protein
CN104041524A (en) * 2014-06-25 2014-09-17 北京燕化永乐生物科技股份有限公司 Sterilization composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
石明旺等: "《新编常用农药安全使用指南》", 31 December 2010 *

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Application publication date: 20160203