CN105278375A - Intelligent automatic microbial detection device and method - Google Patents
Intelligent automatic microbial detection device and method Download PDFInfo
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- CN105278375A CN105278375A CN201510675673.1A CN201510675673A CN105278375A CN 105278375 A CN105278375 A CN 105278375A CN 201510675673 A CN201510675673 A CN 201510675673A CN 105278375 A CN105278375 A CN 105278375A
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- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B19/00—Programme-control systems
- G05B19/02—Programme-control systems electric
- G05B19/04—Programme control other than numerical control, i.e. in sequence controllers or logic controllers
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Abstract
The invention discloses an intelligent automatic microbial detection device and method. Manual intelligence, automatic control, remote communication and other functions are added. Automatic sample adding preprocessing, digital tunable oscillation mixing equipment, microbial warm bath culturing, digital dynamic detection, host computer man-machine interaction processing and the like are comprised. Equipment completely and automatically complete routine work requiring manual operation. Each process is precisely controlled in a digital manner. The quantity and the quality of detection are dramatically improved.
Description
Technical field
The present invention relates to medical microbial detection field, particularly relate to a kind of intelligent automation microbial detection apparatus and method thereof.
Background technology
Existing microbial detection apparatus equipment or instrument, all that detection reagent and body fluid sample to be checked are carried out premixed, then manual operation detects after being positioned over and cultivating in equipment or instrument, draw testing result, and the preprocessing process in its early stage divides several different equipment and step separately to complete, considerably increase working time and the labour intensity of testing staff, and the amount of sample and reagent controls to rely on human eye visual observation or hand dipping to carry out in each process, now in each process, the quality conformance of batch sample is difficult to control, consumptive material used and time is proportional increase also.
Summary of the invention
In order to overcome above-mentioned the deficiencies in the prior art, the invention provides a kind of intelligent automation microbial detection apparatus, manually-operated work is completed automatically by equipment completely, and accurately controls each process by digitizing, make the quantity of testing and quality all have breakthrough raising.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of intelligent automation microbial detection apparatus, is characterized in that, comprises the bath of pre-processing module temperature and cultivates module, digitizing dynamic detection module and host computer conputer controlled center module,
Pre-processing module, for sample pickup, application of sample, mixing and deliver to temperature bath cultivate module;
Module is cultivated in temperature bath, for cultivating the environment of batch sample, accurately controlling, also comprise the bath of required temperature, ice bath temperature:
Digitizing dynamic detection module, for sampling to the detection signal of sample and processing, exports digitized processing data and sends host computer conputer controlled center module to;
Host computer conputer controlled center module, for opertaing device, receives each module data, generation detection data and curve, with outside combined network communication, accepts to perform remote control commands and message exchange.
As the further improvement of such scheme, described pre-processing module comprises automatic sample processing unit and blending unit, described automatic sample processing unit, for completing sample feeding pickup, the automatic control of application of sample, reagent liquid measure is also sent to blending unit, described blending unit, cultivates module for completing different sample by sending temperature bath after preset program mixing to
As the further improvement of such scheme, described automatic sample processing unit comprises application of sample unit and the automatic controlled processing unit of mechanical arm.
As the further improvement of such scheme, described host computer conputer controlled center module comprises remote protocol and control, network remote reference mark and/or client control center and database.
As the further improvement of such scheme, described blending unit adopts variable-frequency ultrasound vortex oscillator arrangement, described variable-frequency ultrasound vortex oscillator arrangement comprises to be installed the seat of honour and installs lower seat, be arranged on the vortex oscillation motor installed on the seat of honour, it is characterized in that: described vortex oscillation motor is connected with eccentric rotary transmission shaft, described eccentric rotary transmission shaft upper end is connected with rocking platform and drives rocking platform to move, and described rocking platform is provided with at least one ultrasonator.
As the further improvement of such scheme, described variable-frequency ultrasound vortex oscillator arrangement also comprises the controller for automatically controlling oscillation frequency and amplitude.
As the further improvement of such scheme, described controller is also provided with and controls power supply and communication interface.
In order to overcome above-mentioned the deficiencies in the prior art, the invention provides a kind of intelligent automation microorganism detection method, manually-operated work is completed automatically by equipment completely, and accurately controls each process by digitizing, make the quantity of testing and quality all have breakthrough raising.
The technical solution adopted for the present invention to solve the technical problems is:
Based on the detection method of intelligent automation microbial detection apparatus, it is characterized in that, comprise the steps:
1) sample to be checked and detection reagent are placed in the test tube flat of equipment, automatic sample and mixing process are carried out to sample and reagent;
2) sample mixtures of application of sample mixing is carried out to the isothermal reaction control of 37 DEG C, carry out one-time detection according in equipment setting detecting sensor per set time, generate a check point, whole sense cycle generates detection curve figure automatically for analyzing reference;
3), after sense cycle completes, testing result automatically exports and is stored in network data base is convenient to inquiry.
As the further improvement of such scheme, described step 1) is specially: the automatic controlled processing unit of mechanical arm carries out automatic sample to sample, be sent to blending unit after application of sample unit completes application of sample, blending unit completes different sample and cultivates unit by sending temperature bath after preset program mixing to.
Beneficial effect of the present invention has:
A kind of intelligent automation microbial detection apparatus of the present invention and method thereof, increase the functions such as artificial intelligence, automatically control, telecommunication, comprise automatic sample pre-treatment, digital adjustable vibration uniform mixing equipment, the bath of microorganism temperature cultivation, digital dynamic detection, host computer man-machine conversation process etc., manually-operated work routine is needed automatically to be completed by equipment completely, and accurately control each process by digitizing, make the quantity of testing and quality be obtained for breakthrough raising.
Accompanying drawing explanation
Below in conjunction with drawings and the specific embodiments, the invention will be further described, wherein:
Fig. 1 is structured flowchart of the present invention;
Fig. 2 is the structural representation of blending unit of the present invention;
Fig. 3 is embodiment of the present invention process flow diagram.
Embodiment
See Fig. 1, a kind of intelligent automation microbial detection apparatus, comprise pre-processing module, described pre-processing module also comprises automatic sample processing unit 1 and blending unit 2, described automatic sample processing unit 1 comprises application of sample unit 11 and the automatic controlled processing unit 12 of mechanical arm, be responsible for the pickup of sample sample introduction, the automatic control of application of sample, reagent liquid measure is also sent to blending unit, utilize mechanical arm automatic controlled processing unit 11 automatic sample, liquid feeding, application of sample, liquid measure are accurately controlled, ensures the consistance detecting sample batch.Described blending unit 2 has been responsible for different sample and has been cultivated module 3 by sending temperature bath after preset program mixing to.
With further reference to Fig. 2, blending unit 2 adopts variable-frequency ultrasound vortex oscillator arrangement, the ultrasonic vortex oscillator arrangement of a kind of medical variable frequency, comprise and the seat of honour 271 is installed and lower seat 272 is installed, be arranged on the vortex oscillation motor 26 installing the seat of honour 271, it is characterized in that: described vortex oscillation motor 26 is connected with eccentric rotary transmission shaft 25, described eccentric rotary transmission shaft 25 upper end is connected with rocking platform 22 and drives rocking platform 22 to move, and described rocking platform 22 is provided with at least one ultrasonator 24 and drives rocking platform to carry out vibration rotation.Described ultrasonator 24 is provided with the clamp device 23 for clamping mixing container 1, the material of described grip device 23 can not be excessively soft, use the engineering plastics of appropriateness, main because oscillation energy is delivered on mixing container by this material require.Between described mount pad 7 and base, damping rubber pad 29 is installed.Described rocking platform 22 is provided with top panel and lower panel, and described top panel and lower panel are equipped with through hole, and described mixing container 1 is placed through top panel through hole.Be provided with damping rubber pad 29 between the described installation seat of honour 271 and the lower seat 272 of installation, reduce the vibrations that device installs desktop, avoiding device moves.This product also comprises the controller 28 for automatically controlling oscillation frequency and amplitude, and described controller 28 is also provided with and controls power supply and communication interface 210, for this product and outside and long-range control and communication, to realize carrying out long-range or automatically controlling.During use, mixed solution is poured in mixing container 21, mixing container 21 is put into the through hole of rocking platform 22, be placed on clamp device 23, after vibration motor 26 is opened, by centrifugal eccentric rotary transmission shaft 25, drive rocking platform 22 to move in a circle.Supersonic oscillations amplitude is little, is arranged on by ultrasonator 4 on rocking platform 22, and the clamp device 23 that ultrasonator 24 is arranged can not only be fixedly clamped and mix container 21, also plays the function transmitting sonic oscillation energy.
Described temperature bath is cultivated module 3 and is responsible for cultivating the environment of batch sample, the bath of required temperature, ice bath temperature are accurately controlled, the bath of batch sample temperature is cultivated, accurate control temperature bath culture environment, carry out in the similar culture environment of the working environment such as sample application, mixing, reduce the difference variation impact of pattern delivery process.Digitizing dynamic detection module 4, is responsible for sampling to the detection signal of sample and processing, exports digitized processing data and send host computer conputer controlled center module to.
In order to improve device intelligence and automaticity, host computer conputer controlled center module 5 also comprises remote protocol and control, network remote reference mark and/or client control center and database, the whole equipment being responsible for being made up of all submodules controls, send various steering order, receive each module data, generate and detect data and curve, with outside combined network communication, accept to perform remote control commands and message exchange.
The another one object of embodiments of the invention is to provide a kind of intelligent automation microorganism detection method, comprises the steps:
1) by sample to be checked and detect reagent be placed in the test tube flat of equipment, to sample and reagent carry out automatic sample and mixing process, transmit a signal to host computer conputer controlled center module after blending unit completes, and sample is sent to temperature bath cultivate module;
2) host computer conputer controlled center module controls to start temperature bath and cultivates module, the isothermal reaction control that the sample mixtures of module to application of sample mixing carries out 37 DEG C is cultivated in temperature bath, digitizing dynamic detection module carries out one-time detection according in equipment setting detecting sensor per set time, generate a check point, whole sense cycle generates detection curve figure automatically for analyzing reference;
3), after sense cycle completes, testing result automatically exports and is stored in network data base is convenient to inquiry.
As the further improvement of such scheme, described step 1) is specially: the automatic controlled processing unit of mechanical arm carries out automatic sample to sample, be sent to blending unit after application of sample unit completes application of sample, blending unit completes different sample and cultivates unit by sending temperature bath after preset program mixing to.
Preferred embodiment, in step 4, the sample mixtures of application of sample mixing is carried out to the isothermal reaction control of 37 DEG C, within every 1 second, carry out one-time detection according to equipment setting detecting sensor, generate a check point, whole sense cycle is 8400 seconds, automatically generates detection curve figure for analyzing reference.
The above, just better embodiment of the present invention, but the present invention is not limited to above-described embodiment, as long as it reaches technique effect of the present invention with any same or similar means, all should belong to protection scope of the present invention.
Claims (9)
1. an intelligent automation microbial detection apparatus, is characterized in that, comprises pre-processing module, module (3), digitizing dynamic detection module (4) and host computer conputer controlled center module (5) are cultivated in temperature bath,
Pre-processing module, for sample pickup, application of sample, mixing and deliver to temperature bath cultivate module;
Module 3 is cultivated in temperature bath), for cultivating the environment of batch sample, the bath of required temperature, ice bath temperature are accurately controlled;
Digitizing dynamic detection module (4), for sampling to the detection signal of sample and processing, exports digitized processing data and sends host computer conputer controlled center module to;
Host computer conputer controlled center module (5), for opertaing device, receives each module data, generation detection data and curve, with outside combined network communication, accepts to perform remote control commands and message exchange.
2. a kind of intelligent automation microbial detection apparatus according to claim 1, it is characterized in that, described pre-processing module comprises automatic sample processing unit (1) and blending unit (2), described automatic sample processing unit (1), for completing sample feeding pickup, the automatic control of application of sample, reagent liquid measure is also sent to blending unit, described blending unit (2), cultivates module for completing different sample by sending temperature bath after preset program mixing to.
3. a kind of intelligent automation microbial detection apparatus according to claim 2, is characterized in that, described automatic sample processing unit (1) comprises application of sample unit (11) and the automatic controlled processing unit of mechanical arm (12).
4. according to a kind of intelligent automation microbial detection apparatus according to claim 1, it is characterized in that, described host computer conputer controlled center module (5) comprises remote protocol and control, network remote reference mark and/or client control center and database.
5. according to a kind of intelligent automation microbial detection apparatus according to claim 2, it is characterized in that, described blending unit (2) adopts variable-frequency ultrasound vortex oscillator arrangement, described variable-frequency ultrasound vortex oscillator arrangement comprises to be installed the seat of honour (271) and installs lower seat (272), be arranged on the vortex oscillation motor (26) installed on the seat of honour (271), it is characterized in that: described vortex oscillation motor (26) is connected with eccentric rotary transmission shaft (25), described eccentric rotary transmission shaft (25) upper end is connected with rocking platform (22) and drives rocking platform (22) to move, described rocking platform (22) is provided with at least one ultrasonator (24).
6. a kind of intelligent automation microbial detection apparatus according to claim 5, is characterized in that, described variable-frequency ultrasound vortex oscillator arrangement also comprises the controller (28) for automatically controlling oscillation frequency and amplitude.
7. a kind of intelligent automation microbial detection apparatus according to claim 6, is characterized in that, described controller (28) is also provided with and controls power supply and communication interface (210).
8. an intelligent automation microorganism detection method, is characterized in that, comprises the steps:
1) sample to be checked and detection reagent are placed in the test tube flat of equipment, automatic sample and mixing process are carried out to sample and reagent;
2) sample mixtures of application of sample mixing is carried out to the isothermal reaction control of 37 DEG C, carry out one-time detection according in equipment setting detecting sensor per set time, generate a check point, whole sense cycle generates detection curve figure automatically for analyzing reference;
3), after sense cycle completes, testing result automatically exports and is stored in network data base is convenient to inquiry.
9. a kind of intelligent automation microorganism detection method according to claim 8, it is characterized in that, described step 1) is specially: the automatic controlled processing unit of mechanical arm carries out automatic sample to sample and is sent to blending unit, and blending unit completes different sample and cultivates unit by sending temperature bath after preset program mixing to.
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| CN201510675673.1A CN105278375A (en) | 2015-10-16 | 2015-10-16 | Intelligent automatic microbial detection device and method |
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Cited By (6)
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| CN105606392A (en) * | 2016-02-16 | 2016-05-25 | 上海屹尧仪器科技发展有限公司 | Full-automatic microwave pretreatment method |
| CN106190816A (en) * | 2016-07-19 | 2016-12-07 | 湖州高亿诺生物科技有限公司 | Automatization's microbial molecules detection equipment |
| CN106737740A (en) * | 2016-12-28 | 2017-05-31 | 苏州祥弘源电子科技有限公司 | A kind of medical treatment intelligence storage robot |
| CN107505439A (en) * | 2017-07-27 | 2017-12-22 | 马鹏飞 | A kind of medicine sterile detector based on robot motion's technology |
| CN109459410A (en) * | 2018-11-21 | 2019-03-12 | 郑州博莱特生物科技有限公司 | The automatic rapid detection system of food microorganisms |
| WO2023178668A1 (en) * | 2022-03-25 | 2023-09-28 | 深圳先进技术研究院 | Microbial growth curve determination apparatus |
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Effective date of registration: 20170525 Address after: 519041 Guangdong province Zhuhai City Sanzao town Jinwan District No. 19 building two jinhaian Road, 4 floor Applicant after: Zhuhai Deere medical equipment Research Institute Co Ltd Address before: 19 No. 519041 Guangdong province Zhuhai City Sanzao town Jinwan District jinhaian Road Applicant before: Zhuhai DL Medical Biotech Co., Ltd. |
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Effective date of registration: 20180427 Address after: 519041 No. 19 Golden Coast Road, San Zao Town, Jin Wan District, Zhuhai, Guangdong Applicant after: Zhuhai DL Medical Biotech Co., Ltd. Address before: 519041 two, 4 floor, No. 19, Golden Coast Road, San Zao Town, Jin Wan District, Zhuhai, Guangdong. Applicant before: Zhuhai Deere medical equipment Research Institute Co Ltd |
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Application publication date: 20160127 |