CN105267935A - Traditional Chinese medicine preparation for treating pediatric iron-deficiency anemia - Google Patents

Traditional Chinese medicine preparation for treating pediatric iron-deficiency anemia Download PDF

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CN105267935A
CN105267935A CN201510835158.5A CN201510835158A CN105267935A CN 105267935 A CN105267935 A CN 105267935A CN 201510835158 A CN201510835158 A CN 201510835158A CN 105267935 A CN105267935 A CN 105267935A
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radix
fructus
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范征美
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating pediatric iron-deficiency anemia. The traditional Chinese medicine preparation comprises melanterite, Chinese dates, Chinese angelica, plant soot, warf lilyturf tuber, tuckahoe, donkey-hide glue, wolfberry fruits, tangerine peel, argy wormwood leaf, common flowering quince fruits, root of doubleteeth pubescent angelica, red peony root, longans, milkvetch root, honeysuckle flower, longan pulp, ginseng, honey, hawthorn fruits, Szechuan lovage rhizome, fineleaf schizonepeta herb, peach seeds, 10-20 parts of common ginger, India madder root and largehead atractylodes rhizome. All the medical materials are used together to achieve the effects of reinforcing qi and nourishing blood, strengthening spleen and harmonizing stomach, as well as nourishing lung and invigorating spleen, and can effectively improve transformation and transportation functions of spleen and stomach of a pediatric patient to ensure that the spleen qi is healthy and the stomach qi is vigorous, the absorption of iron element is enhanced, and the capability of absorbing iron from diets of the pediatric patient is enhanced by increasing the appetite and the digestion-absorption function of organisms, so that the iron element is supplemented and the absorption is improved fundamentally, and the purpose of treating iron-deficiency anemia is achieved.

Description

A kind of Chinese medicine preparation for the treatment of iron Deficiency Anemia
Technical field
The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine preparation can treating iron Deficiency Anemia.
Background technology
Iron Deficiency Anemia is infant modal a kind of anemia in period, and the sickness rate of China less than 2 years old children's is 10% ~ 48.3%.Its basic cause of disease occurred is iron deficiency in body, causes hemoglobin to be synthesized and reduces and a kind of microcytic hypochromic anemia of generation.Clinically except can there is anemia, the biological activity of many iron enzymes also can be reduced because of iron deficiency, and then affect cellular metabolism function, make body occur the performance of a series of non-blood system such as digestive tract function disorder, circulatory function obstacle, immunologic hypofunction, Spirit nerve symptoms of disease and skin mucosal lesions.
Iron Deficiency Anemia is one of modal Deficiency disease of our times, comparatively large to child health harm, therefore is one of pediatric disease of the important control of China.Current Therapeutic Method mainly adopts ferrous succinate, the medicine iron supplement such as ferrous sulfate, be aided with vitamin C, but to produce effects and not bery desirable, main cause is that the course for the treatment of is long, be difficult to whole process adhere to, the particularly heavier gastrointestinal reaction that causes of heavy dose of chalybeate, child's compliance is not good, and avoid more during drug administration, gastrointestinal irritation individual variation is large, appetite is easily caused to decline, even suffer from abdominal pain, diarrhoea, affect gastro-intestinal digestion to absorb, the more difficult object reaching thoroughly improvement and cure, therefore, it is low that people need a kind of cost, be convenient to take, and the medicine of the better anemia of therapeutic effect comes out.
Summary of the invention
Instant invention overcomes the technical deficiency existed in treatment iron Deficiency Anemia at present, provide a kind of determined curative effect, have no side effect, the high and Chinese medicine preparation not easily recurred of cure rate.
The technical solution adopted in the present invention is: a kind of Chinese medicine preparation for the treatment of iron Deficiency Anemia, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Melanteritum 10-20 part, Fructus Jujubae 10-20 part, Radix Angelicae Sinensis 15-25 part, Pulvis Fumi Carbonisatus 10-20 part, Radix Ophiopogonis 10-20 part, Poria 10-20 part, Colla Corii Asini 10-20 part, Fructus Lycii 5-15 part, Pericarpium Citri Reticulatae 10-20 part, Folium Artemisiae Argyi 10-20 part, Fructus Chaenomelis 5-15 part, Radix Angelicae Pubescentis 5-15 part, Radix Paeoniae Rubra 5-15 part, Arillus Longan 15-25 part, Radix Astragali 10-20 part, Flos Lonicerae 10-20 part, Arillus Longan 5-15 part, Radix Ginseng Rubra 10-20 part, Mel 5-15 part, Fructus Crataegi 5-15 part, Rhizoma Chuanxiong 10-20 part, Herba Schizonepetae 10-20 part, Semen Persicae 5-15 part, Rhizoma Zingiberis Preparatum 10-20 part, Radix Rubiae 15-25 part, Rhizoma Atractylodis Macrocephalae 5-15 part.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Melanteritum 10 parts, 10 parts, Fructus Jujubae, Radix Angelicae Sinensis 15 parts, Pulvis Fumi Carbonisatus 10 parts, Radix Ophiopogonis 10 parts, 10 parts, Poria, 10 parts, Colla Corii Asini, Fructus Lycii 5 parts, Pericarpium Citri Reticulatae 10 parts, Folium Artemisiae Argyi 10 parts, Fructus Chaenomelis 5 parts, Radix Angelicae Pubescentis 5 parts, Radix Paeoniae Rubra 5 parts, Arillus Longan 15 parts, the Radix Astragali 10 parts, Flos Lonicerae 10 parts, Arillus Longan 5 parts, Radix Ginseng Rubra 10 parts, Mel 5 parts, Fructus Crataegi 5 parts, Rhizoma Chuanxiong 10 parts, Herba Schizonepetae 10 parts, 5 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 10 parts, Radix Rubiae 15 parts, the Rhizoma Atractylodis Macrocephalae 5 parts.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Melanteritum 12 parts, 12 parts, Fructus Jujubae, Radix Angelicae Sinensis 17 parts, Pulvis Fumi Carbonisatus 12 parts, Radix Ophiopogonis 12 parts, 12 parts, Poria, 12 parts, Colla Corii Asini, Fructus Lycii 7 parts, Pericarpium Citri Reticulatae 12 parts, Folium Artemisiae Argyi 12 parts, Fructus Chaenomelis 7 parts, Radix Angelicae Pubescentis 7 parts, Radix Paeoniae Rubra 7 parts, Arillus Longan 18 parts, the Radix Astragali 12 parts, Flos Lonicerae 12 parts, Arillus Longan 7 parts, Radix Ginseng Rubra 12 parts, Mel 7 parts, Fructus Crataegi 8 parts, Rhizoma Chuanxiong 12 parts, Herba Schizonepetae 12 parts, 8 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 12 parts, Radix Rubiae 18 parts, the Rhizoma Atractylodis Macrocephalae 7 parts.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Melanteritum 14 parts, 14 parts, Fructus Jujubae, Radix Angelicae Sinensis 19 parts, Pulvis Fumi Carbonisatus 14 parts, Radix Ophiopogonis 14 parts, 14 parts, Poria, 14 parts, Colla Corii Asini, Fructus Lycii 9 parts, Pericarpium Citri Reticulatae 14 parts, Folium Artemisiae Argyi 14 parts, Fructus Chaenomelis 9 parts, Radix Angelicae Pubescentis 9 parts, Radix Paeoniae Rubra 9 parts, Arillus Longan 19 parts, the Radix Astragali 14 parts, Flos Lonicerae 14 parts, Arillus Longan 9 parts, Radix Ginseng Rubra 14 parts, Mel 9 parts, Fructus Crataegi 9 parts, Rhizoma Chuanxiong 14 parts, Herba Schizonepetae 14 parts, 9 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 14 parts, Radix Rubiae 19 parts, the Rhizoma Atractylodis Macrocephalae 9 parts.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Melanteritum 16 parts, 16 parts, Fructus Jujubae, Radix Angelicae Sinensis 21 parts, Pulvis Fumi Carbonisatus 16 parts, Radix Ophiopogonis 16 parts, 16 parts, Poria, 16 parts, Colla Corii Asini, Fructus Lycii 11 parts, Pericarpium Citri Reticulatae 16 parts, Folium Artemisiae Argyi 16 parts, Fructus Chaenomelis 11 parts, Radix Angelicae Pubescentis 11 parts, Radix Paeoniae Rubra 11 parts, Arillus Longan 21 parts, the Radix Astragali 16 parts, Flos Lonicerae 16 parts, Arillus Longan 11 parts, Radix Ginseng Rubra 16 parts, Mel 11 parts, Fructus Crataegi 11 parts, Rhizoma Chuanxiong 16 parts, Herba Schizonepetae 16 parts, 11 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 16 parts, Radix Rubiae 21 parts, the Rhizoma Atractylodis Macrocephalae 11 parts.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Melanteritum 18 parts, 18 parts, Fructus Jujubae, Radix Angelicae Sinensis 23 parts, Pulvis Fumi Carbonisatus 18 parts, Radix Ophiopogonis 18 parts, 18 parts, Poria, 18 parts, Colla Corii Asini, Fructus Lycii 13 parts, Pericarpium Citri Reticulatae 18 parts, Folium Artemisiae Argyi 18 parts, Fructus Chaenomelis 13 parts, Radix Angelicae Pubescentis 13 parts, Radix Paeoniae Rubra 13 parts, Arillus Longan 23 parts, the Radix Astragali 18 parts, Flos Lonicerae 18 parts, Arillus Longan 13 parts, Radix Ginseng Rubra 18 parts, Mel 13 parts, Fructus Crataegi 13 parts, Rhizoma Chuanxiong 18 parts, Herba Schizonepetae 18 parts, 13 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 18 parts, Radix Rubiae 21 parts, the Rhizoma Atractylodis Macrocephalae 13 parts.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Melanteritum 20 parts, 20 parts, Fructus Jujubae, Radix Angelicae Sinensis 25 parts, Pulvis Fumi Carbonisatus 20 parts, Radix Ophiopogonis 20 parts, 20 parts, Poria, 20 parts, Colla Corii Asini, Fructus Lycii 15 parts, Pericarpium Citri Reticulatae 20 parts, Folium Artemisiae Argyi 20 parts, Fructus Chaenomelis 15 parts, Radix Angelicae Pubescentis 15 parts, Radix Paeoniae Rubra 15 parts, Arillus Longan 25 parts, the Radix Astragali 20 parts, Flos Lonicerae 20 parts, Arillus Longan 15 parts, Radix Ginseng Rubra 20 parts, Mel 15 parts, Fructus Crataegi 15 parts, Rhizoma Chuanxiong 20 parts, Herba Schizonepetae 20 parts, 15 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 20 parts, Radix Rubiae 25 parts, the Rhizoma Atractylodis Macrocephalae 15 parts.
The instructions of taking of above-mentioned Chinese medicine preparation is: by the raw material Chinese medicine of above-mentioned weight proportion, except Mel, after mixing, traditionally the method for fried Chinese medicine fried twice, after twice fried medicinal liquid mixing, and decoction being taken warmly.Dosage is: be less than 3 years old person, 1 10ml, every day 3 times; 3 years old-6 years old 1 time 20ml, every day 3 times; More than 6 years old each serving with 30ml, every day 3 times.It within 10 days, was 1 course for the treatment of.
The raw material Chinese medicine of above-mentioned Chinese medicine preparation:
Melanteritum, sour in the mouth, cool, return liver, spleen channel.Have drying dampness to eliminate phlegm, eliminating stagnated food and killing intestinal worms, hemostasis enriched blood, the effect of sore of detoxifying.
Fructus Jujubae, sweet in the mouth, warm in nature; Return spleen, stomach warp.There is invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, relax effect of the property of medicine.
Radix Angelicae Sinensis, acrid in the mouth, warm in nature; Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, effect of pain relieving intestine moistening.
Pulvis Fumi Carbonisatus, acrid in the mouth, warm in nature; Attach to the lung and stomach meridians.Have and hold back battalion's hemostasis, heat clearing and blood stasis dispersing, sterilizing powdered medicine effect of fire.
Radix Ophiopogonis, sweet in the mouth, micro-hardship, cold nature; GUIXIN, lung, stomach warp.There is YIN nourishing and the production of body fluid promoting, effect that lung moistening clears away heart-fire.
Poria, sweet in the mouth, light, property are put down; GUIXIN, lung, spleen channel.There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effect of mind tranquilizing and the heart calming.
Colla Corii Asini, sweet in the mouth, slightly warm in nature; Return liver, kidney channel.There is nourishing the blood and yin, effect of vital essence replenishing and marrow benifiting.
Fructus Lycii, sweet in the mouth, property is put down; Enter liver, kidney channel.There is nourishing YIN and supplementing blood, effect of replenishing vital essence to improve eyesight, warming and recuperating the spleen and kidney, recuperating the depleted YANG to cure collapse-syndrome as emergency treatment.
Pericarpium Citri Reticulatae, acrid in the mouth, hardship, warm in nature; Return spleen, stomach, lung meridian.There is regulating the flow of Qi and the middle Jiao, drying dampness to eliminate phlegm, effect of diuretic relieving constipation.
Folium Artemisiae Argyi, bitter in the mouth, pungent, warm in nature; Return spleen, liver, kidney channel.There is vital energy regualting and blood circulation-promoting, by cold damp eliminating, effect of warming the meridian for stopping bleeding.
Fructus Chaenomelis, sour in the mouth, warm in nature; Return liver, spleen channel.There is relaxing muscles and tendons and activating QI and blood in the collateral, effect of removing dampness to restore normal function of the stomach.
Radix Angelicae Pubescentis, acrid in the mouth, hardship, slightly warm in nature; Return liver, kidney, urinary bladder channel.There is expelling wind and dampness, effect of dispersing cold for relieving pain.
Radix Paeoniae Rubra, bitter in the mouth, cold in nature; Return Liver Channel.There is clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, effect of reducing swelling and alleviating pain.
Arillus Longan is sweet in the mouth, temperature, flat.Reinforcing the heart spleen, replenishing QI and blood, strengthening the spleen and stomach, supports muscle.Cure mainly worry impairing spleen, dizzy, insomnia, severe palpitation, emptyly wins, and after being ill or puerperal asthenia, and to lose blood disease due to insufficiency of the spleen caused hematochezia.
The Radix Astragali, sweet in the mouth, slightly warm in nature; Return spleen, lung meridian.There is benefiting QI for strengthening the superficies, tonifying Qi and lifting yang, promoting pus discharge and tissue regeneration strengthening, effect of inducing diuresis to remove edema.
Flos Lonicerae, cold in nature, sweet in the mouth; Attach to the lung and stomach meridians.There is heat-clearing and toxic substances removing, effect of dispelling wind and heat pathogens.
Arillus Longan, sweet in the mouth warm in nature, heart-spleen boosting, fills blood; Have and well have nourishing tonification, fill blood, effect of Fructus Alpiniae Oxyphyllae mind calming, tranquilizing the mind.
Radix Ginseng Rubra, sweet in the mouth, micro-hardship, warm in nature; Return spleen, lung, heart channel.Have strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, effect of nourishing qi to stop.
Mel, sweet in the mouth, property is put down; Return spleen, lung, large intestine channel.There is invigorating middle warmer emergency, nourishing the lung to arrest cough, effect of loosening bowel to relieve constipation.
Fructus Crataegi, sour in the mouth, sweet, slightly warm in nature; Return spleen, stomach, Liver Channel.There is promoting digestion and removing stagnation, effect of promoting blood circulation to remove blood stasis.
Rhizoma Chuanxiong, acrid in the mouth, warm in nature; Return liver, gallbladder, pericardium channel.There is blood-activating and qi-promoting, effect of wind-expelling pain-stopping.
Herba Schizonepetae, acrid in the mouth, slightly warm in nature; Return lung, Liver Channel.Have expelling pathogenic wind from the body surface, rash disappears effect of skin ulcer, hemostasis.
Semen Persicae, sweet in the mouth, hardship, property is put down; Return lung, liver, large intestine channel.There is blood circulation promoting and blood stasis dispelling, moisturize effect of laxation.
Rhizoma Zingiberis Preparatum, bitter in the mouth, pungent, warm in nature; Return spleen, Liver Channel.There is warming spleen and stomach for dispelling cold, effect of warming the meridian for stopping bleeding.
Radix Rubiae, bitter in the mouth, cold in nature; Return Liver Channel.There is cooling blood for hemostasis, blood stasis dispelling, the effect of stimulating the menstrual flow.
The Rhizoma Atractylodis Macrocephalae, sweet in the mouth, hardship, warm in nature; Return spleen, stomach warp.There is invigorating the spleen and replenishing QI, dampness diuretic, effect of strengthening superficial resistance to stop perspiration.
In recent years, due to reasons such as infantile monophagia, eating foreign fast foods, add dietary structure and dietary habit unreasonable, Irondeficiencyanemia is increasing, and human erythrocyte not only has immunologic function, also have modulating T cell and NKT (NK) cytoactive, promote to engulf, the effects such as infection.After iron deficiency anemia, infant hematid immunity function declines, and easily infects.And the traditional Chinese medical science is thought, iron Deficiency Anemia belongs to blood deficiency and insufficiency of the spleen category, damages relevant to the heart, spleen, liver, kidney four deficiency of five ZANG-organs, wherein especially more close with taste relation.The spleen being the foundation of acquired constitution, source of generating QI and blood, taste lose strong then water paddy and are difficult to transporting, and cereal nutrient can not transfer, and QI and blood is difficult to biochemistry, the opinion of traditional Chinese medical science Gu You " blood person, the essence of water is also, biochemical in spleen ", " control blood person, it is main for must controlling spleen ".
Radix Angelicae Sinensis in preparation, Colla Corii Asini, Fructus Lycii, Arillus Longan, the Radix Astragali, Arillus Longan, Radix Ginseng Rubra can blood yiqi, warming and recuperating the spleen and kidney, tonifying Qi and lifting yang, the foundation of acquired constitution is mended in training, adds Fructus Jujubae, makes the sweet Wen Zhirou of the property of medicine, qi and blood tonifying, greatly improve body immunity, all very beneficial to all cards of blood deficiency; Poria, Pericarpium Citri Reticulatae, Fructus Chaenomelis, Fructus Crataegi, energy promoting digestion and removing stagnation, stomach function regulating spleen invigorating, QI invigorating adjust battalion; Can to promote the production of body fluid Mel, Radix Ophiopogonis dry, lung moistening spleen invigorating of dispelling; Folium Artemisiae Argyi, Radix Angelicae Pubescentis, Rhizoma Zingiberis Preparatum, Herba Schizonepetae energy expelling pathogenic wind from the body surface, warming spleen and stomach for dispelling cold, play the effect of strengthening vital QI to eliminate pathogenic factors, logical warm three Jiao; Flos Lonicerae, Pulvis Fumi Carbonisatus energy heat-clearing and toxic substances removing, dispelling wind and heat pathogens, plays anti-inflammation and sterilization, anti-infective effect; Radix Paeoniae Rubra, Semen Persicae, Rhizoma Chuanxiong, Radix Rubiae energy dredge the meridian passage, promoting flow of QI and blood, blood circulation promoting and blood stasis dispelling, effectively improve blood microcirculation; The Rhizoma Atractylodis Macrocephalae, Melanteritum energy removing food stagnancy are stagnant, and dry spleen wets, and reduce phlegm saliva, except distension, eliminate edema due to deficiency of the spleen symptom.All medicines share, play the merit of benefiting QI and nourishing blood, invigorating the spleen and regulating the stomach, lung moistening spleen reinforcing altogether, can effectively improve infant transformation and transportation of the spleen and stomach, make that temper is strong, gastric qi is prosperous, not only strengthen the absorption of ferrum element, also by the digestive and absorptive functions of appetite strengthening and body, strengthen the ability that infant absorbs ferrum from diet, supplement ferrum element, improvement absorption from basic, reach the object for the treatment of iron deficiency anemia.
For investigating clinical efficacy and the safety of medicine of the present invention further, we have selected 40 routine patient diagnosis be iron deficiency anemia and Chinese medical discrimination be weakness of the spleen and stomach infant treatment, wherein man 23 example, female 17 example.Be divided into treatment group and matched group at random, often organize 20 examples, two groups in age, sex, the cause of disease, severity of anemia, tcm syndrome, tongue pulse condition, blood RBC counting, Hb, MCV, MCHC etc., no significant difference (P > 0.05), has comparability.
Diagnostic criteria:
Doctor trained in Western medicine: the diagnostic criteria of the iron Deficiency Anemia formulated by national children hematopathy academic conference in 1988 ,≤6 years old, hemoglobin (Hb) < 110g/L; > 6 years old, Hb < 120g/L.
The traditional Chinese medical science: weakness of the spleen and stomach: the simple and unadorned or Guang Bai Buze of yellowish complexion, fingernail is pale without color, inappetence, extremity fatigue and weakness, or loose stool, lip pale tongue, white and thin fur, weak pulse.
Therapeutic Method:
Treatment group: on the basis of routine feeding, takes Chinese medicine preparation of the present invention, add water fried after take, be less than 3 years old person, 1 10ml, every day 3 times, more than 3 years old person, 1 20ml, every day 3 times.Matched group: on the basis of routine feeding, oral ferrous sulfate (iron-holder 20%) 0.02/kg, point 3 clothes, simultaneously vitamin C 0.1/ time, every day 3 times.Avoid leading to milk, tea, coffee taking.All treat 1 month for two groups, the indexs such as check routine blood test, judge curative effect.
Criterion of therapeutical effect (according to China IDA curative effect determinate standard):
Effective: clinical symptoms substantially disappears or recovers normal, and hemoglobin rises, less than 6 years old > 110g/L, more than 6 years old > 120g/L.
Effective: clinical symptoms is effectively improved, hemoglobin increases before comparatively treating, not yet up to standard.
Invalid: clinical symptoms is without improvement, and hemoglobin is unchanged.
Efficacy result:
1. comparitive study: after treatment, effective 15 examples for the treatment of group, effective 5 examples, invalid 0 example, total effective rate is 100%.Effective 9 examples of matched group, effective 7 examples, invalid 4 examples, total effective rate is 80%.Through statistical procedures, difference has significance (P < 0.05).Detailed results is in table 1.
Table 1: after two groups of case treatments, efficacy result compares
Group Number of cases Effective n (%) Effective n (%) Invalid n (%) Effective percentage (%)
Treatment group 20 15(75) 5(25) 0(0) 100
Matched group 20 9(45) 7(35) 4(20) 80
2. erythrocyte system comparitive study:
After treatment, two groups of Hb, RBC, three indexs such as SF all obviously raise, after treatment group treatment, Hb on average raises 28.9g/L compared with before treatment, after treatment of control group, Hb on average raises 20.1g/L compared with before treatment, and Hb rising amplitude is compared has significant difference (P < 0.01).Detailed results is in table 3.
Table 3: erythrocyte system comparitive study (average x ± s):
3. untoward reaction is compared:
In therapeutic process, there are 4 routine untoward reaction in matched group, shows as gastrointestinal upset, Nausea and vomiting, anorexia, epigastric discomfort, and the symptoms such as stomachache and diarrhoea, treatment group has no obvious adverse reaction.
Result shows, Chinese medicine preparation of the present invention is used for the treatment of iron Deficiency Anemia and has the high and advantage had no side effect of instant effect, short treating period, cure rate, clinic promotion and application.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine preparation for the treatment of iron Deficiency Anemia, chooses Melanteritum 10 parts, 10 parts, Fructus Jujubae, Radix Angelicae Sinensis 15 parts, Pulvis Fumi Carbonisatus 10 parts, Radix Ophiopogonis 10 parts, 10 parts, Poria, 10 parts, Colla Corii Asini, Fructus Lycii 5 parts, Pericarpium Citri Reticulatae 10 parts, Folium Artemisiae Argyi 10 parts, Fructus Chaenomelis 5 parts, Radix Angelicae Pubescentis 5 parts, Radix Paeoniae Rubra 5 parts, Arillus Longan 15 parts, the Radix Astragali 10 parts, Flos Lonicerae 10 parts, Arillus Longan 5 parts, Radix Ginseng Rubra 10 parts, Mel 5 parts, Fructus Crataegi 5 parts, Rhizoma Chuanxiong 10 parts, Herba Schizonepetae 10 parts, 5 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 10 parts, Radix Rubiae 15 parts, the Rhizoma Atractylodis Macrocephalae 5 parts.
Embodiment 2: a kind of Chinese medicine preparation for the treatment of iron Deficiency Anemia, chooses Melanteritum 12 parts, 12 parts, Fructus Jujubae, Radix Angelicae Sinensis 17 parts, Pulvis Fumi Carbonisatus 12 parts, Radix Ophiopogonis 12 parts, 12 parts, Poria, 12 parts, Colla Corii Asini, Fructus Lycii 7 parts, Pericarpium Citri Reticulatae 12 parts, Folium Artemisiae Argyi 12 parts, Fructus Chaenomelis 7 parts, Radix Angelicae Pubescentis 7 parts, Radix Paeoniae Rubra 7 parts, Arillus Longan 18 parts, the Radix Astragali 12 parts, Flos Lonicerae 12 parts, Arillus Longan 7 parts, Radix Ginseng Rubra 12 parts, Mel 7 parts, Fructus Crataegi 8 parts, Rhizoma Chuanxiong 12 parts, Herba Schizonepetae 12 parts, 8 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 12 parts, Radix Rubiae 18 parts, the Rhizoma Atractylodis Macrocephalae 7 parts.
Embodiment 3: a kind of Chinese medicine preparation for the treatment of iron Deficiency Anemia, chooses Melanteritum 14 parts, 14 parts, Fructus Jujubae, Radix Angelicae Sinensis 19 parts, Pulvis Fumi Carbonisatus 14 parts, Radix Ophiopogonis 14 parts, 14 parts, Poria, 14 parts, Colla Corii Asini, Fructus Lycii 9 parts, Pericarpium Citri Reticulatae 14 parts, Folium Artemisiae Argyi 14 parts, Fructus Chaenomelis 9 parts, Radix Angelicae Pubescentis 9 parts, Radix Paeoniae Rubra 9 parts, Arillus Longan 19 parts, the Radix Astragali 14 parts, Flos Lonicerae 14 parts, Arillus Longan 9 parts, Radix Ginseng Rubra 14 parts, Mel 9 parts, Fructus Crataegi 9 parts, Rhizoma Chuanxiong 14 parts, Herba Schizonepetae 14 parts, 9 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 14 parts, Radix Rubiae 19 parts, the Rhizoma Atractylodis Macrocephalae 9 parts.
Embodiment 4: a kind of Chinese medicine preparation for the treatment of iron Deficiency Anemia, chooses Melanteritum 16 parts, 16 parts, Fructus Jujubae, Radix Angelicae Sinensis 21 parts, Pulvis Fumi Carbonisatus 16 parts, Radix Ophiopogonis 16 parts, 16 parts, Poria, 16 parts, Colla Corii Asini, Fructus Lycii 11 parts, Pericarpium Citri Reticulatae 16 parts, Folium Artemisiae Argyi 16 parts, Fructus Chaenomelis 11 parts, Radix Angelicae Pubescentis 11 parts, Radix Paeoniae Rubra 11 parts, Arillus Longan 21 parts, the Radix Astragali 16 parts, Flos Lonicerae 16 parts, Arillus Longan 11 parts, Radix Ginseng Rubra 16 parts, Mel 11 parts, Fructus Crataegi 11 parts, Rhizoma Chuanxiong 16 parts, Herba Schizonepetae 16 parts, 11 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 16 parts, Radix Rubiae 21 parts, the Rhizoma Atractylodis Macrocephalae 11 parts.
Embodiment 5: a kind of Chinese medicine preparation for the treatment of iron Deficiency Anemia, chooses Melanteritum 18 parts, 18 parts, Fructus Jujubae, Radix Angelicae Sinensis 23 parts, Pulvis Fumi Carbonisatus 18 parts, Radix Ophiopogonis 18 parts, 18 parts, Poria, 18 parts, Colla Corii Asini, Fructus Lycii 13 parts, Pericarpium Citri Reticulatae 18 parts, Folium Artemisiae Argyi 18 parts, Fructus Chaenomelis 13 parts, Radix Angelicae Pubescentis 13 parts, Radix Paeoniae Rubra 13 parts, Arillus Longan 23 parts, the Radix Astragali 18 parts, Flos Lonicerae 18 parts, Arillus Longan 13 parts, Radix Ginseng Rubra 18 parts, Mel 13 parts, Fructus Crataegi 13 parts, Rhizoma Chuanxiong 18 parts, Herba Schizonepetae 18 parts, 13 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 18 parts, Radix Rubiae 21 parts, the Rhizoma Atractylodis Macrocephalae 13 parts.
Embodiment 6: a kind of Chinese medicine preparation for the treatment of iron Deficiency Anemia, chooses Melanteritum 20 parts, 20 parts, Fructus Jujubae, Radix Angelicae Sinensis 25 parts, Pulvis Fumi Carbonisatus 20 parts, Radix Ophiopogonis 20 parts, 20 parts, Poria, 20 parts, Colla Corii Asini, Fructus Lycii 15 parts, Pericarpium Citri Reticulatae 20 parts, Folium Artemisiae Argyi 20 parts, Fructus Chaenomelis 15 parts, Radix Angelicae Pubescentis 15 parts, Radix Paeoniae Rubra 15 parts, Arillus Longan 25 parts, the Radix Astragali 20 parts, Flos Lonicerae 20 parts, Arillus Longan 15 parts, Radix Ginseng Rubra 20 parts, Mel 15 parts, Fructus Crataegi 15 parts, Rhizoma Chuanxiong 20 parts, Herba Schizonepetae 20 parts, 15 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 20 parts, Radix Rubiae 25 parts, the Rhizoma Atractylodis Macrocephalae 15 parts.
Below by concrete case, Chinese medicine preparation curative effect of the present invention is verified further:
Case 1
Grandson, man, 4 years old.There is the symptoms such as spiritlessness and weakness, lassitude, anorexia in infant, through examination in hospital routine blood test: erythrocyte 3.0 × 1012/L, hemoglobin 80g/L, serum ferritin 11ug/L, total white blood cells and differential counting normally, are diagnosed as iron Deficiency Anemia the year before.Get Melanteritum 10 parts, 10 parts, Fructus Jujubae, Radix Angelicae Sinensis 15 parts, Pulvis Fumi Carbonisatus 10 parts, Radix Ophiopogonis 10 parts, 10 parts, Poria, 10 parts, Colla Corii Asini, Fructus Lycii 5 parts, Pericarpium Citri Reticulatae 10 parts, Folium Artemisiae Argyi 10 parts, Fructus Chaenomelis 5 parts, Radix Angelicae Pubescentis 5 parts, Radix Paeoniae Rubra 5 parts, Arillus Longan 15 parts, the Radix Astragali 10 parts, Flos Lonicerae 10 parts, Arillus Longan 5 parts, Radix Ginseng Rubra 10 parts, Mel 5 parts, Fructus Crataegi 5 parts, Rhizoma Chuanxiong 10 parts, Herba Schizonepetae 10 parts, 5 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 10 parts, Radix Rubiae 15 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, take after decocting, after 10 days, infant is weak to be alleviated, food of receiving takes a turn for the better, have rosy cheeks, routine blood test display erythrocyte 4.5 × 1012/L, hemoglobin 100g/L, serum ferritin 11ug/L, after continuing to take one week, the infant state of an illness is clearly better, and diet is normal, and sleep is good, and routine blood test is checked, and indices recovers normal, and infant is cured.Follow up a case by regular visits to half a year without recurrence.
Case 2
Song, man, 6 years old.Not steady and sure without the sleep in evening of obvious inducement before infant half a year, easily wake up with a start weeping in dream, body weight and height increases slowly, examination in hospital routine blood test: erythrocyte 2.9 × 1012/L, hemoglobin 78g/L, serum ferritin 11ug/L, total white blood cells and differential counting on the low side, be diagnosed as iron Deficiency Anemia.Infant hospitalization 7 days, played creatinine pin, taken vitamin, rehabilitation efficacy is not obvious.Take medicine of the present invention upon somebody's introduction to treat, get Melanteritum 16 parts, 16 parts, Fructus Jujubae, Radix Angelicae Sinensis 21 parts, Pulvis Fumi Carbonisatus 16 parts, Radix Ophiopogonis 16 parts, 16 parts, Poria, 16 parts, Colla Corii Asini, Fructus Lycii 11 parts, Pericarpium Citri Reticulatae 16 parts, Folium Artemisiae Argyi 16 parts, Fructus Chaenomelis 11 parts, Radix Angelicae Pubescentis 11 parts, Radix Paeoniae Rubra 11 parts, Arillus Longan 21 parts, the Radix Astragali 16 parts, Flos Lonicerae 16 parts, Arillus Longan 11 parts, Radix Ginseng Rubra 16 parts, Mel 11 parts, Fructus Crataegi 11 parts, Rhizoma Chuanxiong 16 parts, Herba Schizonepetae 16 parts, 11 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 16 parts, Radix Rubiae 21 parts, the Rhizoma Atractylodis Macrocephalae 11 parts, take after decocting, after 1 course for the treatment of, the infant mental status takes a turn for the better, sleep improvement, continue to take after treatment in addition in 1 week, the infant mental status recovers normal, night, sleep was good, routine blood test is checked, indices recovers normal, infant is cured.Follow up a case by regular visits to four months without recurrence.
Case 3
Dong, female, 8 years old half.Lassitude was there is without obvious inducement in infant before half a year, pale complexion, conjunctiva palpebrae color is sent out light, the symptoms such as lip and light red tongue are red or pale, growth promoter is slow, examination in hospital routine blood test: erythrocyte 3.2 × 1012/L, hemoglobin 90g/L, serum ferritin 11ug/L, numeration of leukocyte 13 × 109/L, is diagnosed as iron Deficiency Anemia.Get Melanteritum 20 parts, 20 parts, Fructus Jujubae, Radix Angelicae Sinensis 25 parts, Pulvis Fumi Carbonisatus 20 parts, Radix Ophiopogonis 20 parts, 20 parts, Poria, 20 parts, Colla Corii Asini, Fructus Lycii 15 parts, Pericarpium Citri Reticulatae 20 parts, Folium Artemisiae Argyi 20 parts, Fructus Chaenomelis 15 parts, Radix Angelicae Pubescentis 15 parts, Radix Paeoniae Rubra 15 parts, Arillus Longan 25 parts, the Radix Astragali 20 parts, Flos Lonicerae 20 parts, Arillus Longan 15 parts, Radix Ginseng Rubra 20 parts, Mel 15 parts, Fructus Crataegi 15 parts, Rhizoma Chuanxiong 20 parts, Herba Schizonepetae 20 parts, 15 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 20 parts, Radix Rubiae 25 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, take after decocting, take 1 course for the treatment of, infant spirit is clearly better, and has rosy cheeks; After continuing to take 1 course for the treatment of, the infant mental status recovers normal, and receive food, sleep well, routine blood test is checked, and indices recovers normal, and infant is cured.Follow up a case by regular visits to so far without recurrence.

Claims (7)

1. treat a Chinese medicine preparation for iron Deficiency Anemia, it is characterized in that: this Chinese medicine preparation comprises following component:
Melanteritum 10-20 part, Fructus Jujubae 10-20 part, Radix Angelicae Sinensis 15-25 part, Pulvis Fumi Carbonisatus 10-20 part, Radix Ophiopogonis 10-20 part, Poria 10-20 part, Colla Corii Asini 10-20 part, Fructus Lycii 5-15 part, Pericarpium Citri Reticulatae 10-20 part, Folium Artemisiae Argyi 10-20 part, Fructus Chaenomelis 5-15 part, Radix Angelicae Pubescentis 5-15 part, Radix Paeoniae Rubra 5-15 part, Arillus Longan 15-25 part, Radix Astragali 10-20 part, Flos Lonicerae 10-20 part, Arillus Longan 5-15 part, Radix Ginseng Rubra 10-20 part, Mel 5-15 part, Fructus Crataegi 5-15 part, Rhizoma Chuanxiong 10-20 part, Herba Schizonepetae 10-20 part, Semen Persicae 5-15 part, Rhizoma Zingiberis Preparatum 10-20 part, Radix Rubiae 15-25 part, Rhizoma Atractylodis Macrocephalae 5-15 part.
2. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Melanteritum 10 parts, 10 parts, Fructus Jujubae, Radix Angelicae Sinensis 15 parts, Pulvis Fumi Carbonisatus 10 parts, Radix Ophiopogonis 10 parts, 10 parts, Poria, 10 parts, Colla Corii Asini, Fructus Lycii 5 parts, Pericarpium Citri Reticulatae 10 parts, Folium Artemisiae Argyi 10 parts, Fructus Chaenomelis 5 parts, Radix Angelicae Pubescentis 5 parts, Radix Paeoniae Rubra 5 parts, Arillus Longan 15 parts, the Radix Astragali 10 parts, Flos Lonicerae 10 parts, Arillus Longan 5 parts, Radix Ginseng Rubra 10 parts, Mel 5 parts, Fructus Crataegi 5 parts, Rhizoma Chuanxiong 10 parts, Herba Schizonepetae 10 parts, 5 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 10 parts, Radix Rubiae 15 parts, the Rhizoma Atractylodis Macrocephalae 5 parts.
3. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Melanteritum 12 parts, 12 parts, Fructus Jujubae, Radix Angelicae Sinensis 17 parts, Pulvis Fumi Carbonisatus 12 parts, Radix Ophiopogonis 12 parts, 12 parts, Poria, 12 parts, Colla Corii Asini, Fructus Lycii 7 parts, Pericarpium Citri Reticulatae 12 parts, Folium Artemisiae Argyi 12 parts, Fructus Chaenomelis 7 parts, Radix Angelicae Pubescentis 7 parts, Radix Paeoniae Rubra 7 parts, Arillus Longan 18 parts, the Radix Astragali 12 parts, Flos Lonicerae 12 parts, Arillus Longan 7 parts, Radix Ginseng Rubra 12 parts, Mel 7 parts, Fructus Crataegi 8 parts, Rhizoma Chuanxiong 12 parts, Herba Schizonepetae 12 parts, 8 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 12 parts, Radix Rubiae 18 parts, the Rhizoma Atractylodis Macrocephalae 7 parts.
4. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Melanteritum 14 parts, 14 parts, Fructus Jujubae, Radix Angelicae Sinensis 19 parts, Pulvis Fumi Carbonisatus 14 parts, Radix Ophiopogonis 14 parts, 14 parts, Poria, 14 parts, Colla Corii Asini, Fructus Lycii 9 parts, Pericarpium Citri Reticulatae 14 parts, Folium Artemisiae Argyi 14 parts, Fructus Chaenomelis 9 parts, Radix Angelicae Pubescentis 9 parts, Radix Paeoniae Rubra 9 parts, Arillus Longan 19 parts, the Radix Astragali 14 parts, Flos Lonicerae 14 parts, Arillus Longan 9 parts, Radix Ginseng Rubra 14 parts, Mel 9 parts, Fructus Crataegi 9 parts, Rhizoma Chuanxiong 14 parts, Herba Schizonepetae 14 parts, 9 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 14 parts, Radix Rubiae 19 parts, the Rhizoma Atractylodis Macrocephalae 9 parts.
5. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Melanteritum 16 parts, 16 parts, Fructus Jujubae, Radix Angelicae Sinensis 21 parts, Pulvis Fumi Carbonisatus 16 parts, Radix Ophiopogonis 16 parts, 16 parts, Poria, 16 parts, Colla Corii Asini, Fructus Lycii 11 parts, Pericarpium Citri Reticulatae 16 parts, Folium Artemisiae Argyi 16 parts, Fructus Chaenomelis 11 parts, Radix Angelicae Pubescentis 11 parts, Radix Paeoniae Rubra 11 parts, Arillus Longan 21 parts, the Radix Astragali 16 parts, Flos Lonicerae 16 parts, Arillus Longan 11 parts, Radix Ginseng Rubra 16 parts, Mel 11 parts, Fructus Crataegi 11 parts, Rhizoma Chuanxiong 16 parts, Herba Schizonepetae 16 parts, 11 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 16 parts, Radix Rubiae 21 parts, the Rhizoma Atractylodis Macrocephalae 11 parts.
6. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Melanteritum 18 parts, 18 parts, Fructus Jujubae, Radix Angelicae Sinensis 23 parts, Pulvis Fumi Carbonisatus 18 parts, Radix Ophiopogonis 18 parts, 18 parts, Poria, 18 parts, Colla Corii Asini, Fructus Lycii 13 parts, Pericarpium Citri Reticulatae 18 parts, Folium Artemisiae Argyi 18 parts, Fructus Chaenomelis 13 parts, Radix Angelicae Pubescentis 13 parts, Radix Paeoniae Rubra 13 parts, Arillus Longan 23 parts, the Radix Astragali 18 parts, Flos Lonicerae 18 parts, Arillus Longan 13 parts, Radix Ginseng Rubra 18 parts, Mel 13 parts, Fructus Crataegi 13 parts, Rhizoma Chuanxiong 18 parts, Herba Schizonepetae 18 parts, 13 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 18 parts, Radix Rubiae 21 parts, the Rhizoma Atractylodis Macrocephalae 13 parts.
7. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Melanteritum 20 parts, 20 parts, Fructus Jujubae, Radix Angelicae Sinensis 25 parts, Pulvis Fumi Carbonisatus 20 parts, Radix Ophiopogonis 20 parts, 20 parts, Poria, 20 parts, Colla Corii Asini, Fructus Lycii 15 parts, Pericarpium Citri Reticulatae 20 parts, Folium Artemisiae Argyi 20 parts, Fructus Chaenomelis 15 parts, Radix Angelicae Pubescentis 15 parts, Radix Paeoniae Rubra 15 parts, Arillus Longan 25 parts, the Radix Astragali 20 parts, Flos Lonicerae 20 parts, Arillus Longan 15 parts, Radix Ginseng Rubra 20 parts, Mel 15 parts, Fructus Crataegi 15 parts, Rhizoma Chuanxiong 20 parts, Herba Schizonepetae 20 parts, 15 parts, Semen Persicae, Rhizoma Zingiberis Preparatum 20 parts, Radix Rubiae 25 parts, the Rhizoma Atractylodis Macrocephalae 15 parts.
CN201510835158.5A 2015-11-25 2015-11-25 Traditional Chinese medicine preparation for treating pediatric iron-deficiency anemia Pending CN105267935A (en)

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CN103083541A (en) * 2013-02-02 2013-05-08 徐美玲 Drug for treating anemia
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Application publication date: 20160127