CN105232821A - Gum base chewable tablet for treating oral inflammation - Google Patents

Abstract

The invention discloses a gum base chewable tablet for treating oral inflammation. Oral cavity sore removing and anti-inflammation liquid is prepared from, by weight, 22-37 parts of radix scutellariae, 21-28 parts of pseudo-ginseng, 21-25 parts of safflower carthamus, 5-16 parts of cutch, 8-21 parts of blackberry lily, 5-15 parts of honeysuckle, 2-8 parts of indigo naturalis, 5-16 parts of subprostrate sophora, 1-5 parts of calculus bovis factitius, 0.8-3.6 parts of borneol, 2-7 parts of divaricate saposhnikovia roots, 2-7 parts of liquorice, 12-21 parts of fructus forsythiae, 2-11 parts of radix bupleuri, 2.6-5.8 parts of schizonepeta, 12-16 parts of mint, 8-11 parts of vitamin C, 5-9 parts of oryzanol, 28-38 parts of xylitol and 58-98 parts of gum. The gum base chewable tablet has the following advantages that the effect is taken quickly, the treatment time is short, the medicine acting time is long, and the medicine absorption is good.

Description

A kind of gum base chewable tablet being used for the treatment of oral inflammation

Technical field

The present invention relates to a kind of oral medication and preparation method thereof, is the healing potion and preparation method thereof of a kind of acute pharyngitis, oral ulcer, pharyngeal ulcer specifically.

Background technology

Oral ulcer is commonly called as " aphtha ", is a kind of common ulcerative damages disease betiding oral mucosa, is more common in inside lip, the position such as tongue, tongue abdomen, cheek mucosa, vestibule ditch, soft palate, the mucosa at these positions lack keratinization layer or keratinization poor.Tongue ulcer refers to the oral ulcer betiding tongue, tongue abdominal part position.Sharp ache during oral ulcer outbreak, local causalgia is obvious, and severe patient also can affect diet, speak, and causes very big inconvenience to daily life; Can the General Symptoms such as concurrent halitosis, chronic pharyngitis, constipation, headache, dizziness, nauseating, weak, irritated, heating, lymphadenectasis; The infection of whole respiratory system can be caused.

Oral ulcer be the result of many factors comprehensive function, it comprises local wound, psychentonia, food, medicine, malnutrition, hormonal readiness change and vitamin or trace element deficiency.Systemic disease, heredity, immunity and microorganism may play an important role in the generation, development of oral ulcer.As lacked trace element zinc, ferrum, lacking folic acid, vitamin B12 and malnutrition etc., immunologic function can be reduced, increase the probability of oral ulcer morbidity; The antibacterial such as Streptococcus sanguis and helicobacter pylori is also in close relations with oral ulcer.Oral ulcer imply that body may have potential systemic disease usually, and oral ulcer is all relevant with gastric ulcer, duodenal ulcer, ulcerative colitis, regional enteritis, hepatitis, female menstrual period, vitamin B complex malabsorption disease, autonomic nervous dysfunction's disease etc.

The life stress of the current people is large, material requisite is high, the emotion of anxiety causes endocrine disturbance, very easily cause the outbreak of oral inflammation, and the fast pace life of society, the quick food of people's excessive use, the sanitary standard of quick food performs and differs, also easily cause the generation of oral disease, and quick food mostly is fried and cure foods, too much is edible larger to oral health implications, especially the Fructus Capsicis in cure foods etc. stimulate food, very easily cause oral inflammation or ulcer.

Chewing gum requires constantly to chew in oral cavity, and this masticatory movement is gone a long way oral health:

1, chewing can exciting salivary secretion, then in conjunction with the rubbing action of chewing gum on tooth, can strengthen clean, the sterilization functions of tooth, and reduce the cariogenic factor, contribute to preventing decayed tooth, prevent bacteria breed.

2, masticatory movement can promote oral cavity blood circulation, salivation, drives human body oneself immunologic mechanism, the effect of teaching display stand cleaning cleaning oral cavity.

The traditional Chinese medical science often says that illness finds its way in by the mouth, and stomatitis disease and ulcer have a strong impact on the immune system in oral cavity, thus strengthen the infection probability of disease, affect the health of the people, slight oral inflammation or ulcer have had a strong impact on the health of the people, the people are badly in need of the medicament of a kind of effective mass oral inflammation or ulcer, safeguard the health of self.

Summary of the invention

Technical problem to be solved by this invention is to provide a kind of through affected part, and drug residence time is of a specified duration, treatment oral inflammation, ulcer that drug absorption is effective, maintains healing potion of oral immunisation power and preparation method thereof.

For solving the problems of the technologies described above, technical scheme of the present invention is: a kind of gum base chewable tablet being used for the treatment of oral inflammation, be made up of the raw material of following weight portion: Radix Scutellariae: 22-37 part, Radix Notoginseng: 21-28 part, Flos Carthami: 21-25 part, catechu: 5-16 part, Rhizoma Belamcandae: 8-21 part, Flos Lonicerae: 5-15 part, Indigo Naturalis: 2-8 part, Radix Sophorae Tonkinensis: 5-16 part, artificial Calculus Bovis: 1-5 part, Borneolum Syntheticum: 0.8-3.6 part, Radix Saposhnikoviae: 2-7 part, Radix Glycyrrhizae: 2-7 part, Fructus Forsythiae: 12-21 part, Radix Bupleuri: 2-11 part, Herba Schizonepetae: 2.6-5.8 part, Herba Menthae: 12-16 part, vitamin C: 8-11 part, oryzanol: 5-9 part, vitamin B12: 5-11 part, xylitol 28-38 part, gum base: 58-98 part.

As preferred technical scheme, the clear skin ulcer anti-inflammation liquid in described a kind of oral cavity, be made up of following raw material: Radix Scutellariae: 29.5 parts, Radix Notoginseng: 24.5 parts, Flos Carthami: 23 parts, catechu: 10.5 parts, Rhizoma Belamcandae: 14.5 parts, Flos Lonicerae: 10 parts, Indigo Naturalis: 5 parts, Radix Sophorae Tonkinensis: 10.5 parts, artificial Calculus Bovis: 3 parts, Borneolum Syntheticum: 2.2 parts, Radix Saposhnikoviae: 4.5 parts, Radix Glycyrrhizae: 4.5 parts, Fructus Forsythiae: 16.5 parts, Radix Bupleuri: 6.5 parts, Herba Schizonepetae: 4.2 parts, Herba Menthae: 14 parts, vitamin C: 9.5 parts, oryzanol: 7 parts, vitamin B12: 8 parts, xylitol 33 parts, gum base: 78 parts.

Present invention also offers above-mentioned manufacture method, comprise the following steps:

Step one

Radix Scutellariae, Radix Notoginseng, Flos Carthami, catechu, Rhizoma Belamcandae, Flos Lonicerae, Indigo Naturalis, Radix Sophorae Tonkinensis, artificial Calculus Bovis, Borneolum Syntheticum, Radix Saposhnikoviae, Radix Glycyrrhizae, Fructus Forsythiae, Radix Bupleuri, Herba Schizonepetae are taken out according to weight portion, put into frying pan, head decocts the water putting into medical material gross mass 10 times, and after water boiling again, slow fire boils 3 hours; Two decoct the water adding medical material gross mass 8 times again, and after water boiling again, slow fire boils 3 hours, and the medicine soup gross mass obtained after filtering residue is 1 times of medical material gross mass;

Step 2

By the medicine soup that obtains by through Centrifugical extraction, remove the supernatant, the more spray-dried machine of the extraction medicine soup that will obtain is removed moisture and is obtained medicated powder;

Step 3

Gum base is put into baking oven and heats 30min, heating-up temperature is 45 DEG C, makes it soften, obtains softening gum base;

Step 4

By Herba Menthae through micronizing, obtain Herba Menthae powder;

Step 5

In Herba Menthae powder, vitamin C, vitamin B12, oryzanol and softening gum base that medicated powder step 2 obtained, step 4 obtain, pour in blender, the temperature maintaining 45 DEG C stirs 40min, obtains mixing gum base;

Step 6

Mixing gum base is put into forming machine, is processed into high 20mm, wide 10mm, the lamellar body of thick 4mm;

Step 7

Xylitol is melted, pours into and wrap up in pulp grinder, outside the mixing gum base of molding, wrap the thick xylitol of one deck 2mm, can obtain.

Owing to have employed technique scheme, a kind of gum base chewable tablet being used for the treatment of oral inflammation, be made up of following raw material: Radix Scutellariae: 22-37 part, Radix Notoginseng: 21-28 part, Flos Carthami: 21-25 part, catechu: 5-16 part, Rhizoma Belamcandae: 8-21 part, Flos Lonicerae: 5-15 part, Indigo Naturalis: 2-8 part, Radix Sophorae Tonkinensis: 5-16 part, artificial Calculus Bovis: 1-5 part, Borneolum Syntheticum: 0.8-3.6 part, Radix Saposhnikoviae: 2-7 part, Radix Glycyrrhizae: 2-7 part, Fructus Forsythiae: 12-21 part, Radix Bupleuri: 2-11 part, Herba Schizonepetae: 2.6-5.8 part, Herba Menthae: 12-16 part, vitamin C: 8-11 part, oryzanol: 5-9 part, vitamin B12: 5-11 part, xylitol 28-38 part, gum base: 58-98 part,

The present invention has following beneficial effect:

1, with Radix Scutellariae, Radix Notoginseng, Flos Carthami, catechu, Rhizoma Belamcandae, Indigo Naturalis, treat wound face, quick sore reaches the effect of Primary treatment.

2, with Flos Lonicerae, Radix Sophorae Tonkinensis, artificial Calculus Bovis, Borneolum Syntheticum, Radix Saposhnikoviae, Radix Glycyrrhizae, Fructus Forsythiae, Radix Bupleuri, Herba Schizonepetae, Herba Menthae; regulate QI and blood, removing heat from blood is dispelled heat, and anti-bacteria grows; fundamentally treating and preventing oral inflammation, and promoting that the immunity of respiratory system and upper digestive system strengthens.

3, with vitamin C, oryzanol, vitamin B12, replenishing vital QI with drugs of warm nature blood vessel, nerve, regulate emotion, and conditioning endocrine, administers oral inflammation from source, and oryzanol also has the effect promoting ulcer surface healing, and collocation Radix Notoginseng, Flos Carthami wound face curative effect is better.

4, to adopt the medication of chew gum mode, medicine direct effect affected part, in the mastication processes of oral cavity, make drug effect even along with tongue stirs, drug residence time is long, along with the blood circulation speed of masticatory movement human mouth is fast, improve drug absorption effect and tempered again the muscle in oral cavity and mucosa improves resistance.

5, Chinese medicine bitter in the mouth, adding xylitol for convenience of using, promoting mouthfeel when using, xylitol can not think that sugar equally causes oral cavity bacterium to grow simultaneously.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is described further.

embodiment 1

Be used for the treatment of a gum base chewable tablet for oral inflammation, be made up of following raw material: Radix Scutellariae: 22 parts, Radix Notoginseng: 21 parts, Flos Carthami: 21 parts, catechu: 5 parts, Rhizoma Belamcandae: 8 parts, Flos Lonicerae: 5 parts, Indigo Naturalis: 2 parts, Radix Sophorae Tonkinensis: 5 parts, artificial Calculus Bovis: 1 part, Borneolum Syntheticum: 0.8 part, Radix Saposhnikoviae: 2 parts, Radix Glycyrrhizae: 2 parts, Fructus Forsythiae: 12 parts, Radix Bupleuri: 2 parts, Herba Schizonepetae: 2.6 parts, Herba Menthae: 12 parts, vitamin C: 8 parts, oryzanol: 5 parts, xylitol 28 parts, gum base: 58 parts.

Above-mentioned manufacture method, comprises the following steps:

Step one

Radix Scutellariae, Radix Notoginseng, Flos Carthami, catechu, Rhizoma Belamcandae, Flos Lonicerae, Indigo Naturalis, Radix Sophorae Tonkinensis, artificial Calculus Bovis, Borneolum Syntheticum, Radix Saposhnikoviae, Radix Glycyrrhizae, Fructus Forsythiae, Radix Bupleuri, Herba Schizonepetae are taken out according to weight portion, put into frying pan, head decocts the water putting into medical material gross mass 10 times, and after water boiling again, slow fire boils 3 hours; Two decoct the water adding medical material gross mass 8 times again, and after water boiling again, slow fire boils 3 hours, and the medicine soup gross mass obtained after filtering residue is 1 times of medical material gross mass;

Step 2

By the medicine soup that obtains by through Centrifugical extraction, remove the supernatant, the more spray-dried machine of the extraction medicine soup that will obtain is removed moisture and is obtained medicated powder;

Step 3

Gum base is put into baking oven and heats 30min, heating-up temperature is 45 DEG C, makes it soften, obtains softening gum base;

Step 4

By Herba Menthae through micronizing, obtain Herba Menthae powder;

Step 5

By in the Herba Menthae powder of the medicated powder of step 2 acquisition, step 4 acquisition and softening gum base, pour in blender, the temperature maintaining 45 DEG C stirs 40min, obtains mixing gum base;

Step 6

Mixing gum base is put into forming machine, is processed into high 20mm, wide 10mm, the lamellar body of thick 4mm;

Step 7

Xylitol is melted, pours into and wrap up in pulp grinder, outside the mixing gum base of molding, wrap the thick xylitol of one deck 2mm, can obtain.

For investigating the curative effect of above-described embodiment medicine further, we have selected the patient that 100 are suffered from oral ulcer, verify the treatment curative effect of medicine of the present invention.

Be a component with every 50 people be 1 group and 2 groups, 2 groups is matched group, uses oral cavity ulcer powder treatment.

Group

Application method

Patient evaluates

Drag residence

Cure

Treatment duration

Recurrence in half a year

1 group

Chewing gum type chews administration

Medication is convenient, stimulate little, and mouthfeel is fragrant, sweet to affected part

Saliva of buccal cavity Chinese medicine composition retains 10-17 minute

50 people

3-5 days

1 people

2 groups

Pick by swab stick, smear affected part

Medicine-feeding suffering, have secondary damage, and mouthfeel is pained during medicine-feeding to wound

Saliva of buccal cavity Chinese medicine composition retains 5-6 minute

50 people

6-9 days

12 people

embodiment 2

Be used for the treatment of a gum base chewable tablet for oral inflammation, be made up of following raw material: Radix Scutellariae: 37 parts, Radix Notoginseng: 28 parts, Flos Carthami: 25 parts, catechu: 16 parts, Rhizoma Belamcandae: 21 parts, Flos Lonicerae: 15 parts, Indigo Naturalis: 8 parts, Radix Sophorae Tonkinensis: 16 parts, artificial Calculus Bovis: 5 parts, Borneolum Syntheticum: 3.6 parts, Radix Saposhnikoviae: 7 parts, Radix Glycyrrhizae: 7 parts, Fructus Forsythiae: 21 parts, Radix Bupleuri: 11 parts, Herba Schizonepetae: 5.8 parts, Herba Menthae: 16 parts, vitamin C: 11 parts, oryzanol: 9 parts, xylitol 38 parts, gum base: 98 parts.

Above-mentioned manufacture method, comprises the following steps:

Step one

Radix Scutellariae, Radix Notoginseng, Flos Carthami, catechu, Rhizoma Belamcandae, Flos Lonicerae, Indigo Naturalis, Radix Sophorae Tonkinensis, artificial Calculus Bovis, Borneolum Syntheticum, Radix Saposhnikoviae, Radix Glycyrrhizae, Fructus Forsythiae, Radix Bupleuri, Herba Schizonepetae are taken out according to weight portion, put into frying pan, head decocts the water putting into medical material gross mass 10 times, and after water boiling again, slow fire boils 3 hours; Two decoct the water adding medical material gross mass 8 times again, and after water boiling again, slow fire boils 3 hours, and the medicine soup gross mass obtained after filtering residue is 1 times of medical material gross mass;

Step 2

By the medicine soup that obtains by through Centrifugical extraction, remove the supernatant, the more spray-dried machine of the extraction medicine soup that will obtain is removed moisture and is obtained medicated powder;

Step 3

Gum base is put into baking oven and heats 30min, heating-up temperature is 45 DEG C, makes it soften, obtains softening gum base;

Step 4

By Herba Menthae through micronizing, obtain Herba Menthae powder;

Step 5

By in the Herba Menthae powder of the medicated powder of step 2 acquisition, step 4 acquisition and softening gum base, pour in blender, the temperature maintaining 45 DEG C stirs 40min, obtains mixing gum base;

Step 6

Mixing gum base is put into forming machine, is processed into high 20mm, wide 10mm, the lamellar body of thick 4mm;

Step 7

Xylitol is melted, pours into and wrap up in pulp grinder, outside the mixing gum base of molding, wrap the thick xylitol of one deck 2mm, can obtain.

According to patient's service condition, obtain data: so-and-so many places oral ulcer of patient Lee, 2-3 days after medication, wound face starts healing, without obvious pain sense, within 5-6 days, cures; Patient's beam so-and-so, dental bed is red and swollen, gingival hemorrhage, and after medication, after 4 days, dental bed realizes detumescence and recovers so, then without hemorrhage situation; Patient's money many places oral ulcer, dental bed are red and swollen, dental nerve enlargement pain, 8-9 days after medication, and realize ulcer surface convergence, dental bed is subsided a swelling, and dental nerve shrinks, and after 10 days, ulcer surface is eliminated, wound healing.

For investigating the curative effect of above-described embodiment medicine further, we have selected the patient that 100 are suffered from oral ulcer, verify the treatment curative effect of medicine of the present invention.

Be a component with every 50 people be 1 group and 2 groups, 2 groups is matched group, uses oral cavity ulcer powder treatment.

Group

Application method

Patient evaluates

Drag residence

Cure

Treatment duration

Recurrence in half a year

1 group

Chewing gum type chews administration

Medication is convenient, stimulate little, and mouthfeel is fragrant, sweet to affected part

Saliva of buccal cavity Chinese medicine composition retains 10-17 minute

50 people

3-5 days

1 people

2 groups

Pick by swab stick, smear affected part

Medicine-feeding suffering, have secondary damage, and mouthfeel is pained during medicine-feeding to wound

Saliva of buccal cavity Chinese medicine composition retains 5-6 minute

50 people

6-9 days

12 people

embodiment 3

Be used for the treatment of a gum base chewable tablet for oral inflammation, be made up of following raw material: Radix Scutellariae: 29.5 parts, Radix Notoginseng: 24.5 parts, Flos Carthami: 23 parts, catechu: 10.5 parts, Rhizoma Belamcandae: 14.5 parts, Flos Lonicerae: 10 parts, Indigo Naturalis: 5 parts, Radix Sophorae Tonkinensis: 10.5 parts, artificial Calculus Bovis: 3 parts, Borneolum Syntheticum: 2.2 parts, Radix Saposhnikoviae: 4.5 parts, Radix Glycyrrhizae: 4.5 parts, Fructus Forsythiae: 16.5 parts, Radix Bupleuri: 6.5 parts, Herba Schizonepetae: 4.2 parts, Herba Menthae: 14 parts, vitamin C: 9.5 parts, oryzanol: 7 parts, xylitol 33 parts, gum base: 78 parts.

Above-mentioned manufacture method, comprises the following steps:

Step one

Radix Scutellariae, Radix Notoginseng, Flos Carthami, catechu, Rhizoma Belamcandae, Flos Lonicerae, Indigo Naturalis, Radix Sophorae Tonkinensis, artificial Calculus Bovis, Borneolum Syntheticum, Radix Saposhnikoviae, Radix Glycyrrhizae, Fructus Forsythiae, Radix Bupleuri, Herba Schizonepetae are taken out according to weight portion, put into frying pan, head decocts the water putting into medical material gross mass 10 times, and after water boiling again, slow fire boils 3 hours; Two decoct the water adding medical material gross mass 8 times again, and after water boiling again, slow fire boils 3 hours, and the medicine soup gross mass obtained after filtering residue is 1 times of medical material gross mass;

Step 2

By the medicine soup that obtains by through Centrifugical extraction, remove the supernatant, the more spray-dried machine of the extraction medicine soup that will obtain is removed moisture and is obtained medicated powder;

Step 3

Gum base is put into baking oven and heats 30min, heating-up temperature is 45 DEG C, makes it soften, obtains softening gum base;

Step 4

By Herba Menthae through micronizing, obtain Herba Menthae powder;

Step 5

By in the Herba Menthae powder of the medicated powder of step 2 acquisition, step 4 acquisition and softening gum base, pour in blender, the temperature maintaining 45 DEG C stirs 40min, obtains mixing gum base;

Step 6

Mixing gum base is put into forming machine, is processed into high 20mm, wide 10mm, the lamellar body of thick 4mm;

Step 7

Xylitol is melted, pours into and wrap up in pulp grinder, outside the mixing gum base of molding, wrap the thick xylitol of one deck 2mm, can obtain.

For investigating the curative effect of above-described embodiment medicine further, we have selected the patient that 100 are suffered from oral ulcer, verify the treatment curative effect of medicine of the present invention.

Be a component with every 50 people be 1 group and 2 groups, 2 groups is matched group, uses oral cavity ulcer powder treatment.

Group

Application method

Patient evaluates

Drag residence

Cure

Treatment duration

Recurrence in half a year

1 group

Chewing gum type chews administration

Medication is convenient, stimulate little, and mouthfeel is fragrant, sweet to affected part

Saliva of buccal cavity Chinese medicine composition retains 10-17 minute

50 people

3-5 days

1 people

2 groups

Pick by swab stick, smear affected part

Medicine-feeding suffering, have secondary damage, and mouthfeel is pained during medicine-feeding to wound

Saliva of buccal cavity Chinese medicine composition retains 5-6 minute

50 people

6-9 days

12 people

embodiment 4

Be used for the treatment of a gum base chewable tablet for oral inflammation, be made up of following raw material: Radix Scutellariae: 30 parts, Radix Notoginseng: 25 parts, Flos Carthami: 24 parts, catechu: 11 parts, Rhizoma Belamcandae: 15 parts, Flos Lonicerae: 1 part, Indigo Naturalis: 6 parts, Radix Sophorae Tonkinensis: 11 parts, artificial Calculus Bovis: 4 parts, Borneolum Syntheticum: 3 parts, Radix Saposhnikoviae: 5 parts, Radix Glycyrrhizae: 5 parts, Fructus Forsythiae: 17 parts, Radix Bupleuri: 7 parts, Herba Schizonepetae: 5 parts, Herba Menthae: 15 parts, vitamin C: 10 parts, oryzanol: 8 parts, xylitol 40 parts, gum base: 80 parts.

Above-mentioned manufacture method, comprises the following steps:

Step one

Radix Scutellariae, Radix Notoginseng, Flos Carthami, catechu, Rhizoma Belamcandae, Flos Lonicerae, Indigo Naturalis, Radix Sophorae Tonkinensis, artificial Calculus Bovis, Borneolum Syntheticum, Radix Saposhnikoviae, Radix Glycyrrhizae, Fructus Forsythiae, Radix Bupleuri, Herba Schizonepetae are taken out according to weight portion, put into frying pan, head decocts the water putting into medical material gross mass 10 times, and after water boiling again, slow fire boils 3 hours; Two decoct the water adding medical material gross mass 8 times again, and after water boiling again, slow fire boils 3 hours, and the medicine soup gross mass obtained after filtering residue is 1 times of medical material gross mass;

Step 2

By the medicine soup that obtains by through Centrifugical extraction, remove the supernatant, the more spray-dried machine of the extraction medicine soup that will obtain is removed moisture and is obtained medicated powder;

Step 3

Gum base is put into baking oven and heats 30min, heating-up temperature is 45 DEG C, makes it soften, obtains softening gum base;

Step 4

By Herba Menthae through micronizing, obtain Herba Menthae powder;

Step 5

By in the Herba Menthae powder of the medicated powder of step 2 acquisition, step 4 acquisition and softening gum base, pour in blender, the temperature maintaining 45 DEG C stirs 40min, obtains mixing gum base;

Step 6

Mixing gum base is put into forming machine, is processed into high 20mm, wide 10mm, the lamellar body of thick 4mm;

Step 7

Xylitol is melted, pours into and wrap up in pulp grinder, outside the mixing gum base of molding, wrap the thick xylitol of one deck 2mm, can obtain.

For investigating the curative effect of above-described embodiment medicine further, we have selected the patient that 100 are suffered from oral ulcer, verify the treatment curative effect of medicine of the present invention.

Be a component with every 50 people be 1 group and 2 groups, 2 groups is matched group, uses oral cavity ulcer powder treatment.

Group

Application method

Patient evaluates

Drag residence

Cure

Treatment duration

Recurrence in half a year

1 group

Chewing gum type chews administration

Medication is convenient, stimulate little, and mouthfeel is fragrant, sweet to affected part

Saliva of buccal cavity Chinese medicine composition retains 10-17 minute

50 people

3-5 days

1 people

2 groups

Pick by swab stick, smear affected part

Medicine-feeding suffering, have secondary damage, and mouthfeel is pained during medicine-feeding to wound

Saliva of buccal cavity Chinese medicine composition retains 5-6 minute

50 people

6-9 days

12 people

The equipment such as the decocting medicine pot used in manufacture method of the present invention, blender are the common equipment in medical industry field, do not repeat them here.

The foregoing is only the schematic detailed description of the invention of the present invention, and be not used to limit scope of the present invention.Any those skilled in the art, equivalent variations done under the prerequisite not departing from design of the present invention and principle and amendment, all should belong to the scope of protection of the invention.

Claims (3)

1. one kind is used for the treatment of the gum base chewable tablet of oral inflammation, it is characterized in that, be made up of the raw material of following weight portion: Radix Scutellariae: 22-37 part, Radix Notoginseng: 21-28 part, Flos Carthami: 21-25 part, catechu: 5-16 part, Rhizoma Belamcandae: 8-21 part, Flos Lonicerae: 5-15 part, Indigo Naturalis: 2-8 part, Radix Sophorae Tonkinensis: 5-16 part, artificial Calculus Bovis: 1-5 part, Borneolum Syntheticum: 0.8-3.6 part, Radix Saposhnikoviae: 2-7 part, Radix Glycyrrhizae: 2-7 part, Fructus Forsythiae: 12-21 part, Radix Bupleuri: 2-11 part, Herba Schizonepetae: 2.6-5.8 part, Herba Menthae: 12-16 part, vitamin C: 8-11 part, oryzanol: 5-9 part, vitamin B12: 5-11 part, xylitol 28-38 part, gum base: 58-98 part.

2. a kind of gum base chewable tablet being used for the treatment of oral inflammation as claimed in claim 1, it is characterized in that, be made up of the raw material of following weight portion: Radix Scutellariae: 29.5 parts, Radix Notoginseng: 24.5 parts, Flos Carthami: 23 parts, catechu: 10.5 parts, Rhizoma Belamcandae: 14.5 parts, Flos Lonicerae: 10 parts, Indigo Naturalis: 5 parts, Radix Sophorae Tonkinensis: 10.5 parts, artificial Calculus Bovis: 3 parts, Borneolum Syntheticum: 2.2 parts, Radix Saposhnikoviae: 4.5 parts, Radix Glycyrrhizae: 4.5 parts, Fructus Forsythiae: 16.5 parts, Radix Bupleuri: 6.5 parts, Herba Schizonepetae: 4.2 parts, Herba Menthae: 14 parts, vitamin C: 9.5 parts, oryzanol: 7 parts, vitamin B12: 8 parts, xylitol 33 parts, gum base: 78 parts.

3. a kind of manufacture method being used for the treatment of the gum base chewable tablet of oral inflammation as claimed in claim 1 or 2, is characterized in that, comprise the following steps:

Step one

Radix Scutellariae, Radix Notoginseng, Flos Carthami, catechu, Rhizoma Belamcandae, Flos Lonicerae, Indigo Naturalis, Radix Sophorae Tonkinensis, artificial Calculus Bovis, Borneolum Syntheticum, Radix Saposhnikoviae, Radix Glycyrrhizae, Fructus Forsythiae, Radix Bupleuri, Herba Schizonepetae are taken out according to weight portion, put into frying pan, head decocts the water putting into medical material gross mass 10 times, and after water boiling again, slow fire boils 3 hours; Two decoct the water adding medical material gross mass 8 times again, and after water boiling again, slow fire boils 3 hours, and the medicine soup gross mass obtained after filtering residue is 1 times of medical material gross mass;

Step 2

By the medicine soup that obtains by through Centrifugical extraction, remove the supernatant, the more spray-dried machine of the extraction medicine soup that will obtain is removed moisture and is obtained medicated powder;

Step 3

Gum base is put into baking oven and heats 30min, heating-up temperature is 45 DEG C, makes it soften, obtains softening gum base;

Step 4

By Herba Menthae through micronizing, obtain Herba Menthae powder;

Step 5

In Herba Menthae powder, vitamin C, vitamin B12, oryzanol and softening gum base that medicated powder step 2 obtained, step 4 obtain, pour in blender, the temperature maintaining 45 DEG C stirs 40min, obtains mixing gum base;

Step 6

Mixing gum base is put into forming machine, is processed into high 20mm, wide 10mm, the lamellar body of thick 4mm;

Step 7

Xylitol is melted, pours into and wrap up in pulp grinder, outside the mixing gum base of molding, wrap the thick xylitol of one deck 2mm, can obtain.