CN111491648A

CN111491648A - Traditional Chinese medicine composition and preparation method and application thereof

Info

Publication number: CN111491648A
Application number: CN201880028282.2A
Authority: CN
Inventors: 刘志杰
Original assignee: Shenzhen Dedao Health Management Co ltd
Current assignee: Shenzhen Dedao Health Management Co ltd
Priority date: 2018-11-27
Filing date: 2018-11-27
Publication date: 2020-08-04
Also published as: WO2020107225A1

Abstract

A traditional Chinese medicine composition for clearing heat, eliminating dryness, relieving restlessness and relieving fidgetiness and a preparation method and application thereof are disclosed, and the traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 5-75 parts of coptis chinensis, 15-45 parts of scutellaria baicalensis, 15-45 parts of peony and 15-45 parts of honey-fried licorice root. Can be used for treating aphtha, tongue sore, fever without sweat or hypohidrosis, dysphoria, insomnia, restlessness, abdominal pain, diarrhea, and conjunctival congestion due to excessive toxic fire and flaming-up of fire.

Description

Traditional Chinese medicine composition and preparation method and application thereof

Technical Field

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition and a preparation method and application thereof.

Background

Pathogenic heat can cause internal dysfunction of the human body, yang qi failing to astringe and descend and then erupt externally, and the main symptoms include fever, anhidrosis or hypohidrosis, dysphoria in the heart, dysphoria, insomnia, restlessness and sleeping, abdominal pain and diarrhea, skin heat, dampness and itching, conjunctival congestion, aphtha of the mouth and tongue, and the like. In the existing traditional Chinese medicine compound, no traditional Chinese medicine composition with obvious curative effect on the symptoms of the human body caused by pathogenic heat is provided.

Disclosure of Invention

The technical problem to be solved by the invention is as follows: how to provide a traditional Chinese medicine composition capable of effectively treating the diseases caused by pathogenic heat of a human body, a preparation method and application thereof.

In order to solve the technical problems, in a first aspect, the invention provides a traditional Chinese medicine composition, which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 5-75 parts of coptis chinensis, 15-45 parts of scutellaria baicalensis, 15-45 parts of peony and 15-45 parts of honey-fried licorice root.

The further technical scheme is as follows: the traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-21 parts of coptis chinensis, 19-22 parts of scutellaria baicalensis, 18-24 parts of Chinese herbaceous peony and 17-25 parts of honey-fried licorice root.

The further technical scheme is as follows: the traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 33-56 parts of coptis chinensis, 25-30 parts of scutellaria baicalensis, 25-31 parts of Chinese herbaceous peony and 29-35 parts of honey-fried licorice root.

The further technical scheme is as follows: the traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 63-70 parts of coptis chinensis, 35-43 parts of scutellaria baicalensis, 33-42 parts of Chinese herbaceous peony and 35-43 parts of honey-fried licorice root.

The further technical scheme is as follows: the traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 60 parts of coptis chinensis, 30 parts of scutellaria baicalensis, 30 parts of Chinese herbaceous peony and 30 parts of honey-fried licorice root.

In a second aspect, the present invention further provides a method for preparing the traditional Chinese medicine composition according to the first aspect, comprising the following steps:

s1, mixing the following traditional Chinese medicine raw materials: weighing Coptidis rhizoma, Scutellariae radix, radix Paeoniae and radix Glycyrrhizae Preparata at a certain proportion;

s2, soaking the traditional Chinese medicine raw materials in the S1 in water to obtain a mixture;

s3, decocting S2;

s4, filtering, and removing dregs to obtain the medicinal juice.

The further technical scheme is as follows: in the step S2, the mass ratio of the traditional Chinese medicine raw materials to water is 1: 7-9, and the soaking time is 20-40 min.

The further technical scheme is as follows: in the step S3, the mixture is heated to boiling and then continuously decocted at the temperature of 100 ℃ and 115 ℃ for 60-90 min.

The further technical scheme is as follows: in the step S4, the amount of the medicine juice finally obtained is 1/5-3/5 of the weight of the added water.

In a third aspect, the invention provides an application of the traditional Chinese medicine composition in preparation of a medicine for clearing heat, eliminating dryness, relieving restlessness and relieving fidgetiness.

The traditional Chinese medicine composition disclosed by the invention has the effects of clearing heat, eliminating dryness, relieving restlessness and relieving the fidgetiness. The components are mutually matched according to the compatibility of monarch, minister, assistant and guide, and have a synergistic effect, and have obvious curative effects or relieving effects on symptoms such as fever without sweat or less sweat, dysphoria in heart, dysphoria and insomnia, restlessness in sitting and lying, abdominal pain and diarrhea, skin heat and dampness and itching, or conjunctival congestion, aphtha of the mouth and tongue and the like caused by pathogenic heat flaming. Is suitable for clinical application.

Drawings

In order that the present disclosure may be more readily and clearly understood, reference will now be made in detail to the present disclosure, examples of which are illustrated in the accompanying drawings.

Fig. 1 is a flow chart of a preparation method of a traditional Chinese medicine composition provided by the embodiment of the invention.

Detailed Description

In order to explain technical contents, structural features, and objects and effects of the present invention in detail, the following description is given in detail with reference to the embodiments.

The embodiment of the invention provides a traditional Chinese medicine composition, which selects coptis chinensis, scutellaria baicalensis, peony and honey-fried licorice root as traditional Chinese medicine raw materials. Wherein Coptidis rhizoma has effects of clearing heat, eliminating dampness, purging pathogenic fire and removing toxic substance. Can be used for treating damp-heat distention and fullness, emesis, acid regurgitation, dysentery, jaundice, hyperpyrexia, coma, heart fire hyperactivity, vexation, insomnia, blood heat, hematemesis, and epistaxis. Scutellariae radix has effects of clearing heat, eliminating dampness, clearing pathogenic fire, removing toxic substances, stopping bleeding, and preventing miscarriage. Radix Paeoniae has spasmolytic, analgesic, and menstruation promoting effects. The prepared licorice has the treatment effects of tonifying qi, nourishing yin, activating yang and recovering pulse. The 4 traditional Chinese medicine raw materials are mutually matched and have synergistic effect according to the compatibility of monarch, minister, assistant and guide, so that the traditional Chinese medicine composition can be used for treating symptoms such as mouth and tongue sore, dysphoria and the like caused by heat, and patients often have fever, no sweat or little sweat, dysphoria and heat in the heart, dysphoria and insomnia, restlessness and sleeping, abdominal pain and disinhibition when sitting and lying, and skin heat, dampness and itch.

The traditional Chinese medicine composition provided by the embodiment of the invention is mainly used for treating symptoms such as aphtha and tongue sores, dysphoria and the like caused by heat, and patients often have fever, no sweat or little sweat, dysphoria in heart, dysphoria, insomnia, restlessness, abdominal pain and disinhibition during sitting and lying, and skin heat, dampness and itching; when the yin blood of a patient is not injured in the early stage of illness, the egg yolk and the donkey-hide gelatin are not needed to nourish yin and enrich the blood, so the traditional Chinese medicine composition does not contain the egg yolk and the donkey-hide gelatin, and the coptis, the scutellaria and the peony are cold and cool, and the honey-fried licorice root is added to protect the middle warmer due to fear of injuring the stomach qi of the middle warmer and has certain effects of tonifying yin and nourishing blood to prevent yin and bleeding from being injured by dryness pathogen.

The specific embodiment is as follows:

example 1

This example provides a Chinese medicinal composition, which includes coptis root 10g, scutellaria root 15g, peony 15g, and honey-fried licorice root 25 g.

The present invention also provides a method for preparing a Chinese medicinal composition, which comprises the following steps:

s2, adding 455ml of water into the coptis chinensis, the scutellaria baicalensis, the peony and the honey-fried licorice root in the S1, and soaking for 40min to obtain a mixture;

s3, decocting the mixture in S2, heating the mixture to boiling with strong fire, turning the mixture to small fire, and continuously decocting the mixture for 60min at 100 ℃;

s4, turning off the fire, filtering and removing dregs of decoction to obtain 273ml of decoction.

The traditional Chinese medicine composition can be used for preparing medicines for clearing heat, eliminating dryness, relieving restlessness and relieving fidgetiness.

Example 2

The embodiment provides a traditional Chinese medicine composition, which comprises 60g of coptis chinensis, 30g of scutellaria baicalensis, 30g of peony and 30g of honey-fried licorice root.

s2, soaking the coptis chinensis, the scutellaria baicalensis, the peony and the honey-fried licorice root in the S1 in 1200ml of water for 30min to obtain a mixture;

s3, decocting the mixture in S2, heating the mixture to boiling with strong fire, turning the mixture to small fire, and continuously decocting the mixture for 70min at 105 ℃;

s4, turning off the fire, filtering and removing dregs to obtain 600ml of medicinal juice.

Example 3

This example provides a Chinese medicinal composition, which includes 75g of coptis chinensis, 45g of scutellaria baicalensis, 45g of peony, and 45g of honey-fried licorice root.

s2, adding 1890ml of water into the coptis chinensis, the scutellaria baicalensis, the peony and the honey-fried licorice root in the S1, and soaking for 30min to obtain a mixture;

s3, decocting the mixture in S2, heating the mixture to boiling with strong fire, turning the mixture to small fire, and continuously decocting the mixture for 80min at 115 ℃;

s4, turning off the fire, filtering and removing dregs to obtain 378ml of medicinal juice.

Example 4

This example provides a Chinese medicinal composition, which includes coptis root 5g, scutellaria root 25g, peony 20g, and honey-fried licorice root 15 g.

s2, adding 520ml of water into the coptis chinensis, the scutellaria baicalensis, the peony and the honey-fried licorice root in the S1, and soaking for 40min to obtain a mixture;

s4, turning off the fire, filtering and removing dregs of decoction to obtain 260ml of decoction.

Referring to table 1, the present invention also provides the traditional Chinese medicine compositions of examples 5-10, which can be used for preparing the medicines for clearing heat, eliminating dryness, relieving restlessness and relieving fidgetiness.

The examples shown in table 1 can all be prepared by the preparation methods described in examples 1-4,

examples	Coptis (g)	Scutellariae radix (g)	Peony (g)	Prepared licorice (g)
5	9	19	25	17
6	21	43	31	29
7	33	35	42	18
8	56	22	18	43
9	63	18	24	35
10	70	15	33	25

TABLE 1 Chinese medicinal compositions provided in examples 5-10

Examples of the experiments

Subject: the patients have 566 patients in total, wherein 382 patients are male, 184 patients are female, the age distribution is between 15 and 55 years old, and all the patients have aphtha of the mouth and tongue caused by the fire-heat flaming, and the clinical manifestations are fever without sweat or hypohidrosis, dysphoria with smothery sensation in heart, vexation and insomnia, restlessness and sleeping, aphtha of the mouth and tongue, and red, red and erosive wound.

The treatment mode comprises the following steps: the Chinese medicinal composition decoction in the scheme of the embodiment 1 of the invention is taken three times in the morning, at noon and at night, 150 ml and 350ml are taken each time, seven combinations are taken warmly, and clinical curative effect observation is carried out.

The judgment standard of the curative effect is as follows: 1) cure, complete disappearance of symptoms and signs; 2) the effect is obvious, most symptoms and signs disappear after treatment; 3) there was no relief or even a tendency for symptoms and signs to worsen.

And (3) counting the curative effect: according to statistics, in all experimental patients, 408 patients are cured, 89 patients are obviously effective, 69 patients are ineffective, and the total effective rate is 87.8%.

Therefore, the traditional Chinese medicine composition in the scheme has the obvious curative effects of clearing heat, eliminating dryness, dispelling vexation and relieving fidgetiness and the like on the aspect of curing or relieving related diseases such as mouth and tongue sore, dysphoria and the like caused by fire-heat flaring up under the mutual matching and synergistic effect of the traditional Chinese medicine components with specific compatibility, and is suitable for clinical popularization and application.

The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all equivalent flow transformations made by the present specification, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.

Claims

The traditional Chinese medicine composition is characterized by being prepared from the following traditional Chinese medicine raw materials in parts by weight: 5-75 parts of coptis chinensis, 15-45 parts of scutellaria baicalensis, 15-45 parts of peony and 15-45 parts of honey-fried licorice root.
The traditional Chinese medicine composition as claimed in claim 1, which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-21 parts of coptis chinensis, 19-22 parts of scutellaria baicalensis, 18-24 parts of Chinese herbaceous peony and 17-25 parts of honey-fried licorice root.
The traditional Chinese medicine composition as claimed in claim 1, which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 33-56 parts of coptis chinensis, 25-30 parts of scutellaria baicalensis, 25-31 parts of Chinese herbaceous peony and 29-35 parts of honey-fried licorice root.
The traditional Chinese medicine composition as claimed in claim 1, which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 63-70 parts of coptis chinensis, 35-43 parts of scutellaria baicalensis, 33-42 parts of Chinese herbaceous peony and 35-43 parts of honey-fried licorice root.
The traditional Chinese medicine composition as claimed in claim 1, which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 60 parts of coptis chinensis, 30 parts of scutellaria baicalensis, 30 parts of Chinese herbaceous peony and 30 parts of honey-fried licorice root.
A method for preparing the Chinese medicinal composition of any one of claims 1 to 5, comprising the steps of:

s1, mixing the following traditional Chinese medicine raw materials: weighing Coptidis rhizoma, Scutellariae radix, radix Paeoniae and radix Glycyrrhizae Preparata at a certain proportion;

s2, soaking the traditional Chinese medicine raw materials in the S1 in water to obtain a mixture;

s3, decocting S2;

s4, filtering, and removing dregs to obtain the medicinal juice.
The method of claim 6, wherein: in the step S2, the mass ratio of the traditional Chinese medicine raw materials to water is 1: 7-9, and the soaking time is 20-40 min.
The method of claim 6, wherein: in the step S3, the mixture is heated to boiling and then continuously decocted at the temperature of 100 ℃ and 115 ℃ for 60-90 min.
The method of claim 6, wherein: in the step S4, the amount of the medicine juice obtained finally is 1/5-3/5 of the volume of the added water.
Use of the Chinese medicinal composition of any one of claims 1-5 in the preparation of a medicament for clearing heat, eliminating dryness, relieving restlessness and relieving restlessness.