CN104367773A - Traditional Chinese medicine composition for treating periodontitis - Google Patents

Traditional Chinese medicine composition for treating periodontitis Download PDF

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Publication number
CN104367773A
CN104367773A CN201410665548.8A CN201410665548A CN104367773A CN 104367773 A CN104367773 A CN 104367773A CN 201410665548 A CN201410665548 A CN 201410665548A CN 104367773 A CN104367773 A CN 104367773A
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traditional chinese
chinese medicine
medicine composition
periodontitis
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王宝梁
彭阳
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964Anemarrhena

Abstract

The invention discloses a traditional Chinese medicine composition for treating periodontitis, belonging to the field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 12 parts of raw gypsum, 18 parts of rhizome of rehmannia, 9 parts of root-bark of tree peony, 9 parts of common anemarrhena rhizome, 10 parts of green tangerine peel, 15 parts of buerger pipewort flower, 8 parts of herba ecliptae, 6 parts of hairyvein agrimonia herb and bud, 10 parts of honeysuckle flower, 9 parts of divaricate saposhnikovia root, 6 parts of cicada slough and 3 parts of liquoric root. The traditional Chinese medicine composition disclosed by the invention has the beneficial effects that the traditional Chinese medicine composition adopts natural traditional Chinese medicines as raw materials, is accurate in curative effect, does not have toxic or side effects, can be used for effectively curing periodontitis, and ensures that the total effective rate can reach 100%; and periodontitis is not easy to relapse after being cured.

Description

A kind of Chinese medicine composition for the treatment of periodontitis
Technical field
The invention belongs to a kind of department of stomatology medicament, specifically, particularly relate to a kind of Chinese medicine composition for the treatment of periodontitis.
Background technology
Periodontitis is a kind of commonly encountered diseases and frequently-occurring disease, is come to a conclusion as after cancer, cardiovascular and cerebrovascular disease by medical circle, and threatening the third-largest killer of human body health, is also oral health " number one killer ".The chronic inflammatory disease of the Periodontal Supporting Tissue that periodontitis is mainly caused by local factor, age of onset is later comparatively common with 35 years old, and as gingivitis fails to treat in time, inflammation can be diffused into periodontal membrane, alveolar bone and cementum by gingiva to deep layer and develop into periodontitis.The feature of periodontitis is periodontal tissue is chronic destruction, and subjective symptoms is not obvious, mostly is common people not note, once occur dental haemorrhage, pyorrhea, odontoseisis, be shifted or occur periodontal abscess, or symptom aggravation begin just seek medical advice.If periodontal disease is without effective treatment, the number of its loss of tooth is not often single, but most tooth even dental pattern get involved simultaneously.Along with increasing of age, the number increase that periodontitis is ill, and aggravation, therefore control very important the morning of periodontitis anti-morning.Gingival hemorrhage, halitosis are its early symptoms, once find early to treat.At present, the medicament categories for the treatment of periodontitis is a lot, and mainly to play the Western medicine of antiinflammation, but most drug can only relief of symptoms, is difficult to eradicate, and Western medicine to there is price higher, the shortcoming that side effect is larger.
Summary of the invention
The object of the invention is to overcome above-mentioned defect, provide a kind of Chinese medicine composition for the treatment of periodontitis, this Chinese medicine preparation effectively can cure periodontitis, determined curative effect and not easily recurring.
The Chinese medicine composition of described treatment periodontitis, is made up of the crude drug of following weight parts: Gypsum Fibrosum 12, the Radix Rehmanniae 18, Cortex Moutan 9, the Rhizoma Anemarrhenae 9, Pericarpium Citri Reticulatae Viride 10, Flos Eriocauli 15, Herba Ecliptae 8, Herba Agrimoniae 6, Flos Lonicerae 10, Radix Saposhnikoviae 9, Periostracum Cicadae 6, Radix Glycyrrhizae 3.
Single dose dose (unit: gram): Gypsum Fibrosum 12, the Radix Rehmanniae 18, Cortex Moutan 9, the Rhizoma Anemarrhenae 9, Pericarpium Citri Reticulatae Viride 10, Flos Eriocauli 15, Herba Ecliptae 8, Herba Agrimoniae 6, Flos Lonicerae 10, Radix Saposhnikoviae 9, Periostracum Cicadae 6, Radix Glycyrrhizae 3.
Preparation and instructions of taking: be decocted in water for oral dose, every day, potion, divided twice one after each meal sooner or later.
The pharmacological action of each Chinese medicine:
Gypsum Fibrosum: sweet, pungent, Great Cold.Attach to the lung and stomach meridians.Effect with cure mainly: clearing away heat-fire, relieving restlessness is quenched the thirst.For fever caused by exogenous pathogenic factors, high hot excessive thirst, dyspnea and cough due to lung-heat, the high Sheng of stomach-fire, headache, toothache.
The Radix Rehmanniae: sweet, bitter, cold.GUIXIN, liver, kidney channel.Effect with cure mainly: clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting.Thirsty for calentura, internal injury is quenched one's thirst, dryness of the intestine constipation, metrorrhagia of having blood in stool, pyretic toxicity eczema.
Cortex Moutan: bitter, pungent, is slightly cold.GUIXIN, liver, kidney channel.Effect with cure mainly: clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.
The Rhizoma Anemarrhenae: bitter, sweet, cold.Return lung, stomach, kidney channel.Effect with cure mainly: clearing away heat-fire, promote the production of body fluid and moisturize.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Pericarpium Citri Reticulatae Viride: bitter, pungent, temperature.Return liver, gallbladder, stomach warp.Effect with cure mainly: soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant.For distending pain in the chest and hypochondrium, hernia, nodule in the breast, acute mastitis, abdominal pain due to retention of food.
Flos Eriocauli: pungent, sweet is flat.Return liver, lung meridian.Effect with cure mainly: dispelling wind and heat pathogens, improving eyesight, nebula removing.For wind heat conjunctival congestion, swell and ache photophobia, nebula of looking unfamiliar film, headache due to pathogenic wind-heat.
Herba Ecliptae: sweet, sour, cold.Return kidney, Liver Channel.Effect with cure mainly: nourishing the liver and kidney, cooling blood for hemostasis.For odontoseisis, early whitening of beard and hair, vertigo and tinnitus, soreness of the waist and knees, YinXuXueRe, haematemesis, epistaxis, hematuria, dysentery, metrostaxis, traumatic hemorrhage.
Herba Agrimoniae: bitter, puckery is flat.GUIXIN, Liver Channel.Effect with cure mainly: astringing to arrest bleeding, preventing the attack (or recurrence) of malaria, dysentery relieving, removing toxic substances.For hemoptysis, spit blood, metrostaxis, malaria, dysentery, de-power impairment caused by overstrain, carbuncle sore tumefacting virus, pudendal pruritus leukorrhagia.
Flos Lonicerae: sweet, cold.Return lung, the heart, stomach warp.Effect with cure mainly: heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.
Radix Saposhnikoviae: pungent, sweet, tepor.Return bladder, liver, spleen channel.Effect with cure mainly: expelling pathogenic wind from the body surface, can remove aversion to wind ailment said due to cold or exposure, control 36 kinds of wind diseases, tonneau the five internal organs, GUAN-pulse, fall apart stagnant gas in the head, stays wet in meridians.For diaphoresis, dispersing wind and cold, dehumidifying, the pain arthromyodynia that treatment rheumatic arthritis causes.
Periostracum Cicadae: sweet, cold.Return lung, Liver Channel.Effect with cure mainly: loose wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.
Radix Glycyrrhizae: sweet, flat.GUIXIN warp, lung meridian, spleen channel, stomach warp.Effect with cure mainly: QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, be in harmonious proportion the property of medicine.For deficiency-weakness of spleen-QI, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, pathopyretic ulcer, laryngopharynx swelling and pain, medicine, alimentary toxicosis.
The invention has the beneficial effects as follows: the present invention adopts natural Chinese medicine to be raw material, determined curative effect and having no side effect, can effectively cure periodontitis and not easily recur, total effective rate reaches 100%.
Below in conjunction with clinical trial and model case, the present invention is further described
One, clinical trial
1, clinical data: the random selecting patients with periodontitis of 15 to 65 years old 100 example, its mean age is 38 years old, male 46 example, women 54 example, wherein, adult periodontitis 88 example, juvenile periodontitis 12 example.
2, Therapeutic Method: treatment group takes medicine of the present invention, every day, potion, divided twice one after each meal sooner or later.
3, therapeutic outcome: at Clinical practice medicine of the present invention, take medicine 100 routine patients, after taking medicine 5 days, bitter taste xerostomia, Secondary cases gingival hemorrhage and halitosis symptom are alleviated to some extent; After taking medicine 10 days, gingiva hyperemia and edema phenomenon disappear substantially, and symptom is obviously improved; After taking medicine 30 days, the state of an illness is fully recovered.In the routine patient of clinical trial 100, recovery from illness 83 example, effective 17 examples, invalid 0 example, total effective rate is 100%; Wherein juvenile periodontitis is all cured.
Two, model case
Case 1: week certain, female, 49 years old, there is without obvious cause the pain that upper left backteeth is indistinct in patient before 3 years, but not acutely, be sometimes engaged discomfort, cold and hot food of taking food is fitted invariably.By hospital diagnosis, 26,27 gingivas slightly swell, color is red a little, and tooth body has no destruction, visits and all has periodontal pocket, general 4-5mm, 26, there is soft dirt between 27, have subgingival calculus, 26 loosen I degree, and 27 loosen II degree, be pulpitis or periapical periodontitis owing to making a definite diagnosis, therefore only take cephalo and tinidazole carries out antiinflammatory, carry out periodontal scaling simultaneously, curative effect is not satisfactory, has outbreak time still.After take medicine of the present invention after 5 days, red swelling of gingiva phenomenon disappear, cure after taking medicine 10 days, upper left backteeth is not having a dull ache, and can relievedly chew, follow up a case by regular visits to after 1 year without recurrence.
Case 2: in certain, man, 31 years old, gingival hemorrhage 5 years when patient brushes teeth, annual in stomatological hospital toothwash afterwards, but the present brush teeth seriously hemorrhage, then start to see the doctor for treatment, on inspection, patient's oral hygiene is poor, and with halitosis, tartar (+), red swelling of gingiva, lean out blood obvious, subgingival calculus is in the majority, gum nipple gingival hyperplasia, form false periodontal pocket, dental pattern non-loosening, cold stimulation is slightly aobvious responsive.Patient, by full mouth ultrasonic scaling, takes a turn for the better after periodontal rinses and after the medication of all row antibiotic, but still has recurrence, and curative effect is unsatisfied with.After take medicine of the present invention and fully recover after 15 days, red swelling of gingiva and bleeding of brushing teeth disappear, and follow up a case by regular visits to without recurrence after half a year.
Detailed description of the invention
Embodiment
Proportioning (unit: gram): Gypsum Fibrosum 12, the Radix Rehmanniae 18, Cortex Moutan 9, the Rhizoma Anemarrhenae 9, Pericarpium Citri Reticulatae Viride 10, Flos Eriocauli 15, Herba Ecliptae 8, Herba Agrimoniae 6, Flos Lonicerae 10, Radix Saposhnikoviae 9, Periostracum Cicadae 6, Radix Glycyrrhizae 3.
Preparation and instructions of taking: be decocted in water for oral dose, every day, potion, divided twice one after each meal sooner or later.

Claims (1)

1. treat a Chinese medicine composition for periodontitis, it is characterized in that: be made up of the crude drug of following weight parts: Gypsum Fibrosum 12, the Radix Rehmanniae 18, Cortex Moutan 9, the Rhizoma Anemarrhenae 9, Pericarpium Citri Reticulatae Viride 10, Flos Eriocauli 15, Herba Ecliptae 8, Herba Agrimoniae 6, Flos Lonicerae 10, Radix Saposhnikoviae 9, Periostracum Cicadae 6, Radix Glycyrrhizae 3.
CN201410665548.8A 2014-11-19 2014-11-19 Traditional Chinese medicine composition for treating periodontitis Withdrawn CN104367773A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031268A (en) * 2015-08-27 2015-11-11 岳源 Medicine for treating periodontitis and preparation method
CN105031267A (en) * 2015-08-27 2015-11-11 岳源 Prescription for treating periodontitis and preparation method
CN105031269A (en) * 2015-08-27 2015-11-11 岳源 Medicament for treating periodontitis and preparation method of medicament
CN105031270A (en) * 2015-08-27 2015-11-11 岳源 Preparation for preventing and treating periodontitis and preparation method of preparation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102698103A (en) * 2012-06-05 2012-10-03 王素芹 Chinese medicinal preparation for treating periodontitis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102698103A (en) * 2012-06-05 2012-10-03 王素芹 Chinese medicinal preparation for treating periodontitis

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031268A (en) * 2015-08-27 2015-11-11 岳源 Medicine for treating periodontitis and preparation method
CN105031267A (en) * 2015-08-27 2015-11-11 岳源 Prescription for treating periodontitis and preparation method
CN105031269A (en) * 2015-08-27 2015-11-11 岳源 Medicament for treating periodontitis and preparation method of medicament
CN105031270A (en) * 2015-08-27 2015-11-11 岳源 Preparation for preventing and treating periodontitis and preparation method of preparation

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