CN105232686A - Traditional Chinese medicine for treating urticaria - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating urticaria, which is prepared from the following raw material drugs in parts by weight: 10 parts of clickbeetle, 15 parts of fructus ligustri lucidi, 10 parts of frankincense, 15 parts of fructus rosae laevigatae, 30 parts of raw fossil fragment, 10 parts of poria with hostwood, 6 parts of polygala root, 8 parts of the seed of Chinese dodder, and 15 parts of cynomorium songaricum. Clinical experiments prove that the traditional Chinese medicine can be used for safely and effectively treating urticaria.

Description

A kind of Chinese medicine being used for the treatment of rubella

Technical field

The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of rubella.

Background technology

Rubella is a kind of lighter Acute respiratory infectious disease caused by rubella virus, and its Clinical symptoms is the mild inflammation of upper respiratory tract, low grade fever; After special maculopapule and ear, lymphadenectasis after occipitalia and neck.After anemia of pregnant woman's early infection, given birth to baby may be caused to occur various birth defect, be called congenital rubella syndrome.Primary disease is multiple is born in winter and spring, and within less than 5 years old, children's is common.Long-lasting immunity can be obtained, accidental subinfection again after ill.Children's is because of antiperspirant, and separate skirt and undress, wind people space between skin and muscles is fought mutually with QI and blood, ties to have gathered to be connected to urticaria, and pathogenic wind is only superficial at space between skin and muscles, and its gesture is micro-, therefore pneumonedema is not bitterly, but becomes urticaria pruritus ear.

Because its rash point is tiny of husky, Chinese medicine is called " rubella ".

Etiology and pathogenesis pathogenic wind-warm seasonal pathogen enters from mouth and nose, strongly fragrantly defends in lung, accumulates in the flesh natural fibre line of meat, fights mutually with QI and blood, sends out and obtains in skin.Because evil poison is comparatively light, generally only injures lung and defend, therefore the diseases such as visible fever with aversion to wind, cough, watery nasal discharge.Lung governing skin and hair, evil in leaking, so after rash point sends out thoroughly, instant heating moves back and separates.Indivedual exuberant evil_heat, the gas battalion signs such as visible height is warm, thirsty.

Medical material present Research involved in the present invention is as follows:

Pleonomus [another name] jump hundred zhang, jump fight worm, diaphragm arm worm, jump cadelle, Qiu, stripping stripping jump.[source] medical material Ji Yuan: for elaterid animal has the Scorpio of ditch Pleonomus etc.Gather and store: catch spring to autumn after, enter to scald dead in boiling water, dry.[nature and flavor] acrid in the mouth; Tepor.[return through] liver; Kidney channel.[function cures mainly] strong muscles and bones; Preventing the attack (or recurrence) of malaria.Main brothers' flaccidity is soft unable; Littlely do the walking retardation in children; Malaria.[usage and dosage] takes orally: decoct soup, 10 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".

The quick-fried lattice flea of Fructus Ligustri Lucidi [another name], Fructus Ilicis Purpureae.[source] this product is the dry mature fruit of Oleaceae plants Fructus Ligustri Lucidi.Gather during fruit maturation in winter, removing branch and leaf, after slightly steaming or putting in boiling water and slightly scald, dry; Or convection drying.[nature and flavor] sweet, bitter, cold.[return through] returns liver, kidney, warp.[function cures mainly] nourishing the liver and kidney, improving eyesight black hair.For vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision.[usage and dosage] takes orally: decoct soup, 6-12g.[attention] Deficiency and coldness of spleen and stomach is had loose bowels and yang deficiency person avoids clothes.[extracts] " China's book on Chinese herbal medicine ".

Breast flower [another name] Parmelia saxatilis Ach..[source] medical material Ji Yuan: spatter as flower person for loose on clock emulsion dropstone.Gather and store: gathering in limestone cavern, except roguing stone, cleaning.[nature and flavor] are sweet; Temperature; Nontoxic.[return through] returns kidney channel.[function cures mainly] the kidney warming; Bone strengthening; Supporing yang.Main muscles and bones flaccidity is soft; Waist foot cold type of pain; Impotence and premature ejaculation.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".

Fructus Rosae Laevigatae [another name] Cortex Hemipteleae Davidii, sub, golden small-mouthed jar of Fructus Rosae Normalis, Catunaregam spinosa (Thunb.) Tirveng., Gallus jabouillei chieftain, sugared Oriolus chinensis diffusus, Chinese bush cherry ball, sugar bowl, confection, yellow bur, Mel tank, Semen Arecae, golden tall bottle with spout, balaustine, rattan hook, Mantidis fruit, sugared bur [source] this product are the dry mature fruit of rosaceous plant Fructus Rosae Laevigatae Rosa.Gather when 10 ~ November, fruit maturation reddened, dry, except deburring.[nature and flavor] are sour, sweet, puckery, flat.[return through] returns kidney, bladder, large intestine channel.[function cures mainly] reinforcing the kidney and controlling nocturnal emission, reducing urination and antidiarrheal.Control spermatorrhea, the enuresis, frequent micturition, insufficiency of the spleen dysentery, the deficiency of the lung is breathed with cough, spontaneous sweating, bleeding not during menses.[usage and dosage] takes orally: decoct soup, 6 ~ 12g.[attention] has loose bowels because burning hot spouting diarrhea person should not use; Incontinence of urine and vital essence slippage, because of the person of obtaining in deficiency of YIN heated, should not be used.[extracts] " China's book on Chinese herbal medicine ".

Os Draconis [another name] five OS DRACONIS.[source] for ancient times mammal as if the Skeletal Fossils of class, rhinoceros class, Hippocampal cortex etc.[nature and flavor] are sweet, puckery, flat.[return through] enters the heart, liver, kidney, large intestine channel.[function cures mainly] is calm, arresting sweating arresting seminal emission, promoting tissue regeneration and ulcer healing.For neurasthenia, cardiopalmus, insomnia, dreaminess, spontaneous perspiration, night sweat, seminal emission, the enuresis, metrorrhagia, leukorrhagia; External control skin infection for a long time burst do not hold back.[usage and dosage] takes orally: decoct soup, 6 ~ 25g.[attention] has damp and hot, excess pathogen person to avoid clothes.[extracts] " China's book on Chinese herbal medicine ".

Poria cum Radix Pini's [another name] Lignum Poria.In the middle of [source] poria cocos sclerotium, (Poria) entertains the part of Radix Pini massonianae or fine core person.Be cut into thin square more, solid.[nature and flavor] are sweet, flat.[return through] enters the heart, spleen channel.[function cures mainly] mind calming, calms the nerves, diuretic.Control palpitation with fear of having a guilty conscience, forgetful, insomnia, infantile convulsion, dysuria.[usage and dosage] takes orally: decoct soup, 6 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".

Radix Polygalae [another name] Caulis et Folium Polygalae Tenuifoliae, Herba Ceratophylli Demeersi, Chicken Drumsticks, Roots of Polygala tenuifolia, line tea.[source] this product is the dry root of milk wort Radix Polygalae or ovum leaf Radix Polygalae.Spring, Qiu Erji excavate, and removing fibrous root and silt, dry.[nature and flavor] are bitter, pungent, warm.[return through] GUIXIN, kidney, lung meridian.[function cures mainly] to be calmed the nerves Fructus Alpiniae Oxyphyllae, is eliminated the phlegm, detumescence.For the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] Poria, Semen Abutili, Os Draconis are good.Fear natural pearls, Rhizoma et radix veratri (Radix Rhizoma Veratri), cockroach, neat clam.[extracts] " China's book on Chinese herbal medicine ".

Semen Cuscutae [another name] bean parasitism, Cassytha filiformis, yellow silk, Huang Siteng, without ma rattan, golden yellow SIZI.[source] this product is the dry mature seed of convolvulus cuscuta plant.To gather during fruit maturation in autumn plant, dry, lay seed, removing impurity.[nature and flavor] are sweet, temperature.[return through] returns liver,kidney,spleen warp.[function cures mainly] nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.For impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down; Externally treating leucoderma.[usage and dosage] takes orally: decoct soup, 6 ~ 12g.It is good that [attention] obtains wine.Rhizoma Dioscoreae, Colophonium make ， E Di bacterium for it.How fiery kidney man is, and strong sun not flaccidity person avoids it, and constipation due to dry stool person also avoids it.[extracts] " China's book on Chinese herbal medicine ".

Herba Cynomorii [another name] trivial sun, Herba Cynomorii, rust iron staff, ball top, yellow bone wolf, Songaria Cynomorium Herb.[source] this product is the dry meat stem of Cynomoriaceae plant Herba Cynomorii.Spring excavates, and removing inflorescence, cutting, dries.[nature and flavor] are sweet, temperature.[return through] returns spleen, kidney, large intestine channel.[function cures mainly] kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.Soft for waist knee joint flaccidity, sexual impotence spermatorrhea, dryness of the intestine constipation.[usage and dosage] takes orally: decoct soup, 5 ~ 9g.[attention] stool is sliding; Essence is not solid, and constipation contained by fire, and Yang Daoyi lifts, and flatulence of having a guilty conscience, all forbids.[extracts] " China's book on Chinese herbal medicine ".

Summary of the invention

The present invention aims to provide a kind of Chinese medicine being used for the treatment of rubella, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing rubella.

In order to achieve the above object, the present invention is by the following technical solutions:

A kind of Chinese medicine being used for the treatment of rubella, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Pleonomus 10 parts, Fructus Ligustri Lucidi 15 parts, breast spend 10 parts, Fructus Rosae Laevigatae 15 parts, Os Draconis 30 parts, Poria cum Radix Pini 10 parts, Radix Polygalae 6 parts, Semen Cuscutae 8 parts, Herba Cynomorii 15 parts.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, physical data

Outpatient service is collected and rubella patient 296 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 196 example and matched group 100 example at random, treatment group man 87 example, female 109 example; Matched group man 64 example, female 36 example.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.

Diagnostic criteria

Diagnostic criteria according to the meeting of national rubella clinical speciality:

Lab testing:

1. peripheral hemogram total white blood cells reduces, lymphocytosis, and occurs heteromorphic lymphocyte,heteromorphous lymphocyte and plasma cell.

2. quick diagnosis adopts direct immunofluorescence to look into Detecting Rubella Virus Antibodies In Human Sera in throat swab smear exfoliated cell, and its diagnostic value is still needed and observed further.

3. the general rubella patient of virus purification gets nasopharyngeal secretions, congenital rubella patient gets urine, cerebrospinal fluid, blood, bone marrow etc. and is incubated at the passage cells such as RK-13, CCL 81 (verocells) or CCL 60 (SIRCcells), separable go out rubella virus, then to identify by immunofluorescence.

4. serum antibody measures as hemagglutination inhibition test (HI test), neutralization test, complement fixation test and immunofluorescence, and Paired Sera Antibody is tired and increased more than 4 times for positive.Wherein the most frequently used with hemagglutination inhibition test (HI test), because it has quick, easy, reliable advantage, this antibody occurs when eruption, within 1 ~ 2 week, rises rapidly, is down to level during beginning, and can maintains lifelong after 4 ~ 12 months.In order to survey rubella specific antibody IgM and IgG.Merocrine secretion's type IgA antibody can check in nasopharynx part secretions, helps diagnosis.Also useful detected by dot blot hybridization rubella virus RNA.Rubella retinitis is often the important even only sign of Diagnosis of Congenital rubella.Normal point-like not of uniform size or the speckle shape pigment spot occurring brown or pitchy on retina, patient with severe symptoms is except speckle is thick and with yellow crystalline body.The normal compared with normal of retinal vessel is carefully narrow.

5. other auxiliary examinations: patient ECG and the heart zymogram of complicated myocardial inflammation all change.

2, test method

2.1 Therapeutic Method

The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.7 days courses for the treatment of.

Matched group oral ribavirin, a 0.3g, 3 times on the one, 7 days courses for the treatment of.

3, criterion of therapeutical effect and therapeutic outcome

3.1 criterion of therapeutical effect

Cure: through treatment after, then heat or motion after without erythra show effect, whole body is without sensation of pricking;

Effective: heat or the rear erythra of motion obviously reduce, and only deposit minority position, without whole body sensation of pricking, slightly gargalesthesia.

Invalid: erythra does not reduce, still tingle.

3.2 therapeutic outcomes are in table 1.

Table 1 liang group comparitive study

Visible, the medicine that the present invention obtains can safe and effective treatment rubella, has promotional value.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Embodiment 1

Take: Pleonomus 10 grams, Fructus Ligustri Lucidi 15 grams, breast spend 10 grams, Fructus Rosae Laevigatae 15 grams, Os Draconis 30 grams, Poria cum Radix Pini 10 grams, Radix Polygalae 6 grams, Semen Cuscutae 8 grams, Herba Cynomorii 15 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.

Be used for the treatment of rubella.Oral, every bu Morning Afternoon Evening is taken for three times.

Embodiment 2

Take: Pleonomus 10 grams, Fructus Ligustri Lucidi 15 grams, breast spend 10 grams, Fructus Rosae Laevigatae 15 grams, Os Draconis 30 grams, Poria cum Radix Pini 10 grams, Radix Polygalae 6 grams, Semen Cuscutae 8 grams, Herba Cynomorii 15 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.

Be used for the treatment of rubella.Oral, every bu Morning Afternoon Evening is taken for three times.

Embodiment 3

Take: Pleonomus 10 grams, Fructus Ligustri Lucidi 15 grams, breast spend 10 grams, Fructus Rosae Laevigatae 15 grams, Os Draconis 30 grams, Poria cum Radix Pini 10 grams, Radix Polygalae 6 grams, Semen Cuscutae 8 grams, Herba Cynomorii 15 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.

Be used for the treatment of rubella.Oral, every bu Morning Afternoon Evening is taken for three times.

Claims (4)

1. one kind is used for the treatment of the Chinese medicine of rubella, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Pleonomus 10 parts, Fructus Ligustri Lucidi 15 parts, breast spend 10 parts, Fructus Rosae Laevigatae 15 parts, Os Draconis 30 parts, Poria cum Radix Pini 10 parts, Radix Polygalae 6 parts, Semen Cuscutae 8 parts, Herba Cynomorii 15 parts.

2. be used for the treatment of the Chinese medicine of rubella as claimed in claim 1, it is characterized in that, its preparation method is: take: Pleonomus 10 parts, Fructus Ligustri Lucidi 15 parts, breast spend 10 parts, Fructus Rosae Laevigatae 15 parts, Os Draconis 30 parts, Poria cum Radix Pini 10 parts, Radix Polygalae 6 parts, Semen Cuscutae 8 parts, Herba Cynomorii 15 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.

3. be used for the treatment of the Chinese medicine of rubella as claimed in claim 1, it is characterized in that, its preparation method is: take: Pleonomus 10 parts, Fructus Ligustri Lucidi 15 parts, breast spend 10 parts, Fructus Rosae Laevigatae 15 parts, Os Draconis 30 parts, Poria cum Radix Pini 10 parts, Radix Polygalae 6 parts, Semen Cuscutae 8 parts, Herba Cynomorii 15 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.

4. be used for the treatment of the Chinese medicine of rubella as claimed in claim 1, it is characterized in that, its preparation method is: take: Pleonomus 10 parts, Fructus Ligustri Lucidi 15 parts, breast spend 10 parts, Fructus Rosae Laevigatae 15 parts, Os Draconis 30 parts, Poria cum Radix Pini 10 parts, Radix Polygalae 6 parts, Semen Cuscutae 8 parts, Herba Cynomorii 15 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.