CN105194353A - Traditional Chinese medicine oral liquid for treating hypertension and preparation method - Google Patents
Traditional Chinese medicine oral liquid for treating hypertension and preparation method Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine oral liquid for treating hypertension and a preparation method. The traditional Chinese medicine oral liquid is prepared from the following raw materials in parts by weight: 38-42 parts of gambir plant, 28-32 parts of Danshen root, 13-17 parts of dogbane leaf, 13-17 parts of tall gastrodia tuber, 18-22 parts of white paeony root, 13-17 parts of seaweed, 18-22 parts of common selfheal fruit-spike, 18-22 parts of tortoise shell, 13-17 parts of chrysanthemum morofolium Ramat, 18-22 parts of cassia seed, 28-32 parts of oriental waterplantain rhizome, 18-22 parts of earthworm, 28-32 parts of sea-ear shell and 38-42 parts of Indian buead. The traditional Chinese medicine oral liquid has the functions of nourishing yin and calming the liver, dredging collaterals and suppressing yang and clearing heat and promoting diuresis and is a safe and reliable traditional Chinese medicine composition which does not have any toxic or side effect, has high active ingredient usage rate and takes effect quickly.
Description
Technical field
The present invention relates to one and treat hypertensive Chinese medicine oral liquid, belong to the field of Chinese medicines.
Background technology
In recent years, along with the transformation of people life style, increasing people has suffered from various chronic disease, hypertension is exactly one wherein, data shows, China's more than 18 years old hypertensive prevalence of adult is 18.8%, and raise with advancing age, the Prevalence of Hypertension of more than 60 years old old peoples reaches more than 40%, " hypertension is a kind of cardio-vascular clinical syndrome being main manifestations with blood pressure rising, it can be one of clinical manifestation of various diseases, just as diabetes, how not serious the harm of hypertension itself is, but it can cause the infringement of heart and brain kidney and blood vessel, thus cause serious consequence ", the western medical treatment Main Means taked this disease at present uses antihypertensive drugs, but western medicine is temporary transient symptom management mostly, life-time service easily produces dependency and toxic and side effects.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide one and treat hypertensive Chinese medicine oral liquid, it has effect of nourish yin and calm the liver, dredging collateral YANG hyperactivity suppressing, clearing away heat-damp and promoting diuresis.
The present invention is achieved through the following technical solutions:
One treats hypertensive Chinese medicine oral liquid, is made up of following raw material: Ramulus Uncariae Cum Uncis 38-42 part, Radix Salviae Miltiorrhizae 28-32 part, Herba Apocyni veneti 13-17 part, Rhizoma Gastrodiae 13-17 part, Radix Paeoniae Alba 18-22 part, Sargassum 13-17 part, Spica Prunellae 18-22 part, Carapax et Plastrum Testudinis 18-22 part, Flos Chrysanthemi 13-17 part, Semen Cassiae 18-22 part, Rhizoma Alismatis 28-32 part, Pheretima 18-22 part, Concha Haliotidis 28-32 part, Poria 38-42 part.
Preferably, each parts by weight of raw materials is: Ramulus Uncariae Cum Uncis 40 parts, Radix Salviae Miltiorrhizae 30 parts, Herba Apocyni veneti 15 parts, 15 parts, Rhizoma Gastrodiae, the Radix Paeoniae Alba 20 parts, Sargassum 15 parts, Spica Prunellae 20 parts, Carapax et Plastrum Testudinis 20 parts, Flos Chrysanthemi 15 parts, Semen Cassiae 20 parts, Rhizoma Alismatis 30 parts, Pheretima 20 parts, Concha Haliotidis 30 parts, 40 parts, Poria.
Pharmacological action:
Ramulus Uncariae Cum Uncis: nature and flavor with return through: sweet, cool; Return liver, pericardium channel, function with cure mainly: heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion; Dizzy for having a headache, dysphoric cold, infantile convulsion is twitched, pre-eclampsia; Hypertension.
Radix Salviae Miltiorrhizae: nature and flavor with return through: bitter, be slightly cold; GUIXIN, Liver Channel, function with cure mainly: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness; For menoxenia, amenorrhea dysmenorrhea, note of the ancient Chinese abdominal mass is gathered, breast ventral spine pain, pyretic arthralgia pain, and skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Herba Apocyni veneti: nature and flavor with return through sweet, bitter, cold; Return Liver Channel, function with cure mainly: suppressing the hyperactive liver is calmed the nerves, clearing away heat and promoting diuresis; For dizziness due to hyperactivity of liver-YANG, palpitation and insomnia, edema oliguria; Hypertension, neurasthenia, nephritis edema.
Rhizoma Gastrodiae: nature and flavor with return through: sweet, flat; Return Liver Channel, function with cure mainly: suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion; Dizzy for having a headache, numb limbs and tense tendons, infantile convulsion, epilepsy clonus, tetanus.
The Radix Paeoniae Alba: nature and flavor with return through: bitter, sour, be slightly cold; Return liver, spleen channel, function with cure mainly: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating; Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Sargassum: nature and flavor with return through: bitter, salty, cold; Return liver, stomach, kidney channel, function with cure mainly: hard masses softening and resolving, expectorant, diuretic; For goiter, scrofula, painful and swollen testis, phlegm retention edema.
Spica Prunellae: nature and flavor with return through: pungent, bitter, cold; Return liver, gallbladder meridian, function with cure mainly: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence; For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Carapax et Plastrum Testudinis: meridian distribution of property and flavor: salty sweet is flat; Enter the heart, spleen, liver three warp; Effect: YIN nourishing, YANG hyperactivity suppressing, the kidney invigorating, strong bone; Cure mainly: control deficiency of kidney yin, hectic fever due to YIN-deficiency consumptive fever, spit blood, epistaxis, chronic cough, seminal emission, metrorrhagia, leukorrhagia, lumbago, the atrophic debility of bones, stirring of wind due to deficiency of YIN, chronic dysentery, chronic malaria, hemorrhoid, non-closure of fontanels jin infants.
Flos Chrysanthemi: meridian distribution of property and flavor: pungent, sweet, bitter, is slightly cold; Return liver, lung meridian; Effect: wind and heat dispersing, removing toxic substances, improving eyesight; For affection due to external wind and heat and epidemic febrile disease from the beginning of, heating, dizzy headache, wind-heat of liver channel or liver-fire attack caused conjunctival congestion and swelling pain, the disease such as liver wind headache and excessive rising of liver-YANG headache, dizzy and furuncle swelling toxin.
Semen Cassiae: nature and flavor with return through: sweet, bitter, salty, be slightly cold; Return liver, large intestine channel, function with cure mainly: clearing away heat to improve acuity of vision, loosening bowel to relieve constipation; For the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, constipation.
Rhizoma Alismatis: nature and flavor with return through: sweet, cold; Return kidney, urinary bladder channel, function with cure mainly: diuresis, clearing away damp-heat; For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.
Pheretima: nature and flavor with return through: salty, cold; Return liver, spleen, urinary bladder channel, function with cure mainly: heat clearing away is calmed the frightened, and dredging collateral is relievingd asthma, diuresis; For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.
Concha Haliotidis: nature and flavor with return through: salty, cold; Return Liver Channel, function with cure mainly: suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving; Dizzy for having a headache, cataract, blurring of vision, optic atrohic blindness nyctalopia.
Poria: nature and flavor with return through: sweet, light, flat; GUIXIN, lung, spleen, kidney channel, function with cure mainly: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming; For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Another technical problem to be solved by this invention is to provide a kind of preparation method preparing above-mentioned Chinese medicine oral liquid.
Another technical problem to be solved by this invention is achieved through the following technical solutions:
Treat a preparation method for hypertensive Chinese medicine oral liquid, be prepared from by following methods:
(1) get raw material Ramulus Uncariae Cum Uncis, Radix Salviae Miltiorrhizae, Herba Apocyni veneti, Rhizoma Gastrodiae, the Radix Paeoniae Alba, Sargassum, Spica Prunellae put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(2) get raw material Flos Chrysanthemi, Semen Cassiae, Rhizoma Alismatis, Pheretima, Concha Haliotidis, Poria put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(3) get raw material Carapax et Plastrum Testudinis and put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filter, collect filtrate, obtain filtrate, for subsequent use;
(4) gained filtrate in gained filtrate in gained filtrate in step (1) and step (2) and step (3) is put into container to be fully uniformly mixed, agitator revolution is 300-500r/min, then the ethanol of 50-80% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilters, obtain admixing medical solutions, for subsequent use;
(5) gained admixing medical solutions in step (4) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-50nm, and the pressure limit crossed in filter fly is 0.1-0.4MPa, and the scope of the crossflow velocity in filter process is 3-6m/s, obtain filtrate, for subsequent use;
(6) gained filtrate in step (5) is sent into receiver, in receiver, be evaporated to the clear paste of relative density 1.01-1.08 during 60-65 DEG C, obtain clear paste, for subsequent use;
(7) by gained clear paste in step (6) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in soda-lime glass tubular oral liquid bottle again, and fill is rolled lid and is placed on 95-98 DEG C of condition, sterilizing 15-18min, warehouse-in is finished product, must treat hypertensive Chinese medicine oral liquid.
Preferably, a kind of preparation method for the treatment of hypertensive Chinese medicine oral liquid, is prepared from by following methods:
(1) get raw material Ramulus Uncariae Cum Uncis, Radix Salviae Miltiorrhizae, Herba Apocyni veneti, Rhizoma Gastrodiae, the Radix Paeoniae Alba, Sargassum, Spica Prunellae put into boiling machine, by cold water soak 30 minutes, then add the soak by water secondary of above-mentioned raw materials volume 10 times, each 2 hours, collecting decoction, filtered, collect filtrate, obtain filtrate, for subsequent use;
(2) get raw material Flos Chrysanthemi, Semen Cassiae, Rhizoma Alismatis, Pheretima, Concha Haliotidis, Poria put into boiling machine, by cold water soak 30 minutes, then add the soak by water secondary of above-mentioned raw materials volume 10 times, each 2 hours, collecting decoction, filtered, collect filtrate, obtain filtrate, for subsequent use;
(3) get raw material Carapax et Plastrum Testudinis and put into boiling machine, by cold water soak 30 minutes, then add the soak by water secondary of above-mentioned raw materials volume 10 times, each 2 hours, collecting decoction, filter, collect filtrate, obtain filtrate, for subsequent use;
(4) gained filtrate in gained filtrate in gained filtrate in step (1) and step (2) and step (3) is put into container to be fully uniformly mixed, agitator revolution is 400r/min, then the ethanol of 70% is added by volume, leave standstill 48 hours, filter, filtrate recycling ethanol, refilters, obtain admixing medical solutions, for subsequent use;
(5) gained admixing medical solutions in step (4) is put into ultrafilter to filter, the average pore size of the filter membrane of described ultrafilter is 50nm, and the pressure limit crossed in filter fly is 0.4MPa, and the scope of the crossflow velocity in filter process is 5m/s, obtains filtrate, for subsequent use;
(6) gained filtrate in step (5) is sent into receiver, when being evaporated to 65 DEG C in receiver, the clear paste of relative density 1.08, obtains clear paste, for subsequent use;
(7) by gained clear paste sodium hydroxide solution adjust ph to 6.8 in step (6), then embedding is in soda-lime glass tubular oral liquid bottle, and fill is rolled lid and is placed on 98 DEG C of conditions, sterilizing 15min, and warehouse-in is finished product, must treat hypertensive Chinese medicine oral liquid.
Beneficial effect: the present invention has effect of nourish yin and calm the liver, dredging collateral YANG hyperactivity suppressing, clearing away heat-damp and promoting diuresis, be a kind of safe and reliable, without any side effects, effective ingredient utilization rate is high, the Chinese medicine composition of instant effect.
The present invention adopts pure Chinese medicine to be raw material, according to hypertensive pathogenic factor and Clinical symptoms, under instruction of Chinese Medicine theory, carry out prescription be prepared from the basis not being raw-material activity, show through clinical efficacy, this medicine has definite curative effect to hypertension, is the ideal treatment medication of a kind of hyperpietic.
Model case
Case 1: Mrs Shang, 48 years old, medical history: dizzy dizziness several days, measuring blood pressure 170/110mmHg, examine as hypertension, take Drug therapy of the present invention one week, after treatment, patient is conscious dizzyly dizzyly obviously to reduce, after taking a course for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears completely, follows up a case by regular visits to half a year without recurrence.
Case 2: Mr. Deng, 50 years old, medical history: discontinuity dizziness, headache 6 years, increase the weight of 3 days, suffer from hypertension 1 year, take a course for the treatment of of Drug therapy of the present invention, the conscious headache of patient after treatment, dizziness obviously reduce, after taking two courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears completely, follows up a case by regular visits to half a year without recurrence.
Case 3: Mrs Meng, 58 years old, medical history: hypertension history 3 years, within nearly three days, once there is uncomfortable in chest, chest pain, measuring blood pressure 160/100mmHg, takes a course for the treatment of of Drug therapy of the present invention, and after treatment, conscious uncomfortable in chest, the chest pain of patient obviously reduces, after taking three courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears completely, follows up a case by regular visits to half a year without recurrence.
Case 4: Mr. Ou, 63 years old, medical history: hypertension history 5 years, within nearly three days, once there is uncomfortable in chest, chest pain, measuring blood pressure l50/95mmHg, takes a course for the treatment of of Drug therapy of the present invention, and after treatment, conscious uncomfortable in chest, the chest pain of patient obviously reduces, after taking three courses for the treatment of of medicine of the present invention again, patient's above-mentioned symptom disappears completely, follows up a case by regular visits to half a year without recurrence.
Case 5: Mr. Wei, 65 years old, medical history: hypertension 3 years, dizzy 2 weeks of interruption, blood pressure is surveyed as 160/110mmHg, without other special discomfort, take a course for the treatment of of Drug therapy of the present invention, after treatment, patient is conscious dizzyly dizzyly obviously to reduce, after taking three courses for the treatment of of medicine of the present invention again, patient's above-mentioned symptom disappears completely, follows up a case by regular visits to half a year without recurrence.
Case 6: Mr. Xie, 60 years old, medical history: hypertension 5 years, be interrupted dizziness, headache 2 years, increase the weight of first quarter moon, measuring blood pressure l50/105mmHg, take a course for the treatment of of Drug therapy of the present invention, after treatment, patient is conscious dizzy dizzy obviously reduces, then after taking three courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears completely, follows up a case by regular visits to half a year without recurrence.
Clinical data
Physical data: hyperpietic 50 example, male 30 example, women 20 example, age 37-80 year.
Diagnostic method: Measure blood pressure is the Main Means of hypertension diagnosis and classification, usually indirect method is adopted to record pressure value at upper arm brachial artery position clinically, whether need could judge that blood pressure raises through non-three repeated measurements is on the same day persistence, twice blood pressure is had at least to raise (2/3 time), diagnosable is hypertension, notes distinguishing former and secondary hypertension.
Therapeutic Method: take oral liquid of the present invention, every day 2 times, each 30ml one month is a course for the treatment of.
Curative effect determinate standard: (1) effective: more than diastolic pressure decline 10mmHg (1.3KPa), and reach normal range; Though diastolic pressure is not down to normally, declined 20mmHg (2.67KPa) or more; Systolic pressure comparatively treats front more than decline 30mmHg, and reaches normal range, possesses wherein one; (2) effective: diastolic pressure declines not as good as 10mmHg (1.67KPa), but reaches normal range; Diastolic pressure decline 10-19mmHg, but do not reach normal range; Systolic pressure comparatively treats front more than decline 30mmHg, but does not reach normal range.Possesses wherein one; (3) invalid: not reach above standard.
Therapeutic outcome: by this side treatment hyperpietic 50 example, effective 45 examples, effective 5 examples, invalid 0 example, total effective rate 100%.
Detailed description of the invention
Embodiment 1
The present invention treats the preparation of hypertension Chinese medicine oral liquid, and the weight portion of each raw material is: Ramulus Uncariae Cum Uncis 42 parts, Radix Salviae Miltiorrhizae 32 parts, Herba Apocyni veneti 17 parts, 17 parts, Rhizoma Gastrodiae, the Radix Paeoniae Alba 22 parts, Sargassum 17 parts, Spica Prunellae 22 parts, Carapax et Plastrum Testudinis 22 parts, Flos Chrysanthemi 17 parts, Semen Cassiae 22 parts, Rhizoma Alismatis 32 parts, Pheretima 22 parts, Concha Haliotidis 32 parts, 42 parts, Poria;
Be prepared from by following methods:
(1) get raw material Ramulus Uncariae Cum Uncis, Radix Salviae Miltiorrhizae, Herba Apocyni veneti, Rhizoma Gastrodiae, the Radix Paeoniae Alba, Sargassum, Spica Prunellae put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(2) get raw material Flos Chrysanthemi, Semen Cassiae, Rhizoma Alismatis, Pheretima, Concha Haliotidis, Poria put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(3) get raw material Carapax et Plastrum Testudinis and put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filter, collect filtrate, obtain filtrate, for subsequent use;
(4) gained filtrate in gained filtrate in gained filtrate in step (1) and step (2) and step (3) is put into container to be fully uniformly mixed, agitator revolution is 300-500r/min, then the ethanol of 50-80% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilters, obtain admixing medical solutions, for subsequent use;
(5) gained admixing medical solutions in step (4) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-50nm, and the pressure limit crossed in filter fly is 0.1-0.4MPa, and the scope of the crossflow velocity in filter process is 3-6m/s, obtain filtrate, for subsequent use;
(6) gained filtrate in step (5) is sent into receiver, in receiver, be evaporated to the clear paste of relative density 1.01-1.08 during 60-65 DEG C, obtain clear paste, for subsequent use;
(7) by gained clear paste in step (6) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in soda-lime glass tubular oral liquid bottle again, and fill is rolled lid and is placed on 95-98 DEG C of condition, sterilizing 15-18min, warehouse-in is finished product, must treat hypertensive Chinese medicine oral liquid.
Usage: oral, every day 2 times, each 30ml.
Embodiment 2
The present invention treats the preparation of hypertension Chinese medicine oral liquid, and the weight portion of each raw material is: Ramulus Uncariae Cum Uncis 40 parts, Radix Salviae Miltiorrhizae 30 parts, Herba Apocyni veneti 15 parts, 15 parts, Rhizoma Gastrodiae, the Radix Paeoniae Alba 20 parts, Sargassum 15 parts, Spica Prunellae 20 parts, Carapax et Plastrum Testudinis 20 parts, Flos Chrysanthemi 15 parts, Semen Cassiae 20 parts, Rhizoma Alismatis 30 parts, Pheretima 20 parts, Concha Haliotidis 30 parts, 40 parts, Poria;
Be prepared from by following methods:
(1) get raw material Ramulus Uncariae Cum Uncis, Radix Salviae Miltiorrhizae, Herba Apocyni veneti, Rhizoma Gastrodiae, the Radix Paeoniae Alba, Sargassum, Spica Prunellae put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(2) get raw material Flos Chrysanthemi, Semen Cassiae, Rhizoma Alismatis, Pheretima, Concha Haliotidis, Poria put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(3) get raw material Carapax et Plastrum Testudinis and put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filter, collect filtrate, obtain filtrate, for subsequent use;
(4) gained filtrate in gained filtrate in gained filtrate in step (1) and step (2) and step (3) is put into container to be fully uniformly mixed, agitator revolution is 300-500r/min, then the ethanol of 50-80% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilters, obtain admixing medical solutions, for subsequent use;
(5) gained admixing medical solutions in step (4) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-50nm, and the pressure limit crossed in filter fly is 0.1-0.4MPa, and the scope of the crossflow velocity in filter process is 3-6m/s, obtain filtrate, for subsequent use;
(6) gained filtrate in step (5) is sent into receiver, in receiver, be evaporated to the clear paste of relative density 1.01-1.08 during 60-65 DEG C, obtain clear paste, for subsequent use;
(7) by gained clear paste in step (6) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in soda-lime glass tubular oral liquid bottle again, and fill is rolled lid and is placed on 95-98 DEG C of condition, sterilizing 15-18min, warehouse-in is finished product, must treat hypertensive Chinese medicine oral liquid.
Usage: oral, every day 2 times, each 30ml.
Embodiment 3
The present invention treats the preparation of hypertension Chinese medicine oral liquid, and the weight portion of each raw material is: Ramulus Uncariae Cum Uncis 38 parts, Radix Salviae Miltiorrhizae 28 parts, Herba Apocyni veneti 13 parts, 13 parts, Rhizoma Gastrodiae, the Radix Paeoniae Alba 18 parts, Sargassum 13 parts, Spica Prunellae 18 parts, Carapax et Plastrum Testudinis 18 parts, Flos Chrysanthemi 13 parts, Semen Cassiae 18 parts, Rhizoma Alismatis 28 parts, Pheretima 18 parts, Concha Haliotidis 28 parts, 38 parts, Poria;
Be prepared from by following methods:
(1) get raw material Ramulus Uncariae Cum Uncis, Radix Salviae Miltiorrhizae, Herba Apocyni veneti, Rhizoma Gastrodiae, the Radix Paeoniae Alba, Sargassum, Spica Prunellae put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(2) get raw material Flos Chrysanthemi, Semen Cassiae, Rhizoma Alismatis, Pheretima, Concha Haliotidis, Poria put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(3) get raw material Carapax et Plastrum Testudinis and put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filter, collect filtrate, obtain filtrate, for subsequent use;
(4) gained filtrate in gained filtrate in gained filtrate in step (1) and step (2) and step (3) is put into container to be fully uniformly mixed, agitator revolution is 300-500r/min, then the ethanol of 50-80% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilters, obtain admixing medical solutions, for subsequent use;
(5) gained admixing medical solutions in step (4) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-50nm, and the pressure limit crossed in filter fly is 0.1-0.4MPa, and the scope of the crossflow velocity in filter process is 3-6m/s, obtain filtrate, for subsequent use;
(6) gained filtrate in step (5) is sent into receiver, in receiver, be evaporated to the clear paste of relative density 1.01-1.08 during 60-65 DEG C, obtain clear paste, for subsequent use;
(7) by gained clear paste in step (6) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in soda-lime glass tubular oral liquid bottle again, and fill is rolled lid and is placed on 95-98 DEG C of condition, sterilizing 15-18min, warehouse-in is finished product, must treat hypertensive Chinese medicine oral liquid.
Usage: oral, every day 2 times, each 30ml.
Claims (6)
1. treat a hypertensive Chinese medicine oral liquid, it is characterized in that: be made up of following raw material: Ramulus Uncariae Cum Uncis 38-42 part, Radix Salviae Miltiorrhizae 28-32 part, Herba Apocyni veneti 13-17 part, Rhizoma Gastrodiae 13-17 part, Radix Paeoniae Alba 18-22 part, Sargassum 13-17 part, Spica Prunellae 18-22 part, Carapax et Plastrum Testudinis 18-22 part, Flos Chrysanthemi 13-17 part, Semen Cassiae 18-22 part, Rhizoma Alismatis 28-32 part, Pheretima 18-22 part, Concha Haliotidis 28-32 part, Poria 38-42 part.
2. one according to claim 1 treats hypertensive Chinese medicine oral liquid, it is characterized in that: the weight portion of each raw material is: Ramulus Uncariae Cum Uncis 40 parts, Radix Salviae Miltiorrhizae 30 parts, Herba Apocyni veneti 15 parts, 15 parts, Rhizoma Gastrodiae, the Radix Paeoniae Alba 20 parts, Sargassum 15 parts, Spica Prunellae 20 parts, Carapax et Plastrum Testudinis 20 parts, Flos Chrysanthemi 15 parts, Semen Cassiae 20 parts, Rhizoma Alismatis 30 parts, Pheretima 20 parts, Concha Haliotidis 30 parts, 40 parts, Poria.
3. one according to claim 1 treats hypertensive Chinese medicine oral liquid, it is characterized in that: the weight portion of each raw material is: Ramulus Uncariae Cum Uncis 42 parts, Radix Salviae Miltiorrhizae 32 parts, Herba Apocyni veneti 17 parts, 17 parts, Rhizoma Gastrodiae, the Radix Paeoniae Alba 22 parts, Sargassum 17 parts, Spica Prunellae 22 parts, Carapax et Plastrum Testudinis 22 parts, Flos Chrysanthemi 17 parts, Semen Cassiae 22 parts, Rhizoma Alismatis 32 parts, Pheretima 22 parts, Concha Haliotidis 32 parts, 42 parts, Poria.
4. one according to claim 1 treats hypertensive Chinese medicine oral liquid, it is characterized in that: the weight portion of each raw material is: Ramulus Uncariae Cum Uncis 38 parts, Radix Salviae Miltiorrhizae 28 parts, Herba Apocyni veneti 13 parts, 13 parts, Rhizoma Gastrodiae, the Radix Paeoniae Alba 18 parts, Sargassum 13 parts, Spica Prunellae 18 parts, Carapax et Plastrum Testudinis 18 parts, Flos Chrysanthemi 13 parts, Semen Cassiae 18 parts, Rhizoma Alismatis 28 parts, Pheretima 18 parts, Concha Haliotidis 28 parts, 38 parts, Poria.
5. a kind of preparation method for the treatment of hypertensive Chinese medicine oral liquid according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) get raw material Ramulus Uncariae Cum Uncis, Radix Salviae Miltiorrhizae, Herba Apocyni veneti, Rhizoma Gastrodiae, the Radix Paeoniae Alba, Sargassum, Spica Prunellae put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(2) get raw material Flos Chrysanthemi, Semen Cassiae, Rhizoma Alismatis, Pheretima, Concha Haliotidis, Poria put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(3) get raw material Carapax et Plastrum Testudinis and put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filter, collect filtrate, obtain filtrate, for subsequent use;
(4) gained filtrate in gained filtrate in gained filtrate in step (1) and step (2) and step (3) is put into container to be fully uniformly mixed, agitator revolution is 300-500r/min, then the ethanol of 50-80% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilters, obtain admixing medical solutions, for subsequent use;
(5) gained admixing medical solutions in step (4) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-50nm, and the pressure limit crossed in filter fly is 0.1-0.4MPa, and the scope of the crossflow velocity in filter process is 3-6m/s, obtain filtrate, for subsequent use;
(6) gained filtrate in step (5) is sent into receiver, in receiver, be evaporated to the clear paste of relative density 1.01-1.08 during 60-65 DEG C, obtain clear paste, for subsequent use;
(7) by gained clear paste in step (6) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in soda-lime glass tubular oral liquid bottle again, and fill is rolled lid and is placed on 95-98 DEG C of condition, sterilizing 15-18min, warehouse-in is finished product, must treat hypertensive Chinese medicine oral liquid.
6. a kind of preparation method for the treatment of hypertensive Chinese medicine oral liquid according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) get raw material Ramulus Uncariae Cum Uncis, Radix Salviae Miltiorrhizae, Herba Apocyni veneti, Rhizoma Gastrodiae, the Radix Paeoniae Alba, Sargassum, Spica Prunellae put into boiling machine, by cold water soak 30 minutes, then add the soak by water secondary of above-mentioned raw materials volume 10 times, each 2 hours, collecting decoction, filtered, collect filtrate, obtain filtrate, for subsequent use;
(2) get raw material Flos Chrysanthemi, Semen Cassiae, Rhizoma Alismatis, Pheretima, Concha Haliotidis, Poria put into boiling machine, by cold water soak 30 minutes, then add the soak by water secondary of above-mentioned raw materials volume 10 times, each 2 hours, collecting decoction, filtered, collect filtrate, obtain filtrate, for subsequent use;
(3) get raw material Carapax et Plastrum Testudinis and put into boiling machine, by cold water soak 30 minutes, then add the soak by water secondary of above-mentioned raw materials volume 10 times, each 2 hours, collecting decoction, filter, collect filtrate, obtain filtrate, for subsequent use;
(4) gained filtrate in gained filtrate in gained filtrate in step (1) and step (2) and step (3) is put into container to be fully uniformly mixed, agitator revolution is 400r/min, then the ethanol of 70% is added by volume, leave standstill 48 hours, filter, filtrate recycling ethanol, refilters, obtain admixing medical solutions, for subsequent use;
(5) gained admixing medical solutions in step (4) is put into ultrafilter to filter, the average pore size of the filter membrane of described ultrafilter is 50nm, and the pressure limit crossed in filter fly is 0.4MPa, and the scope of the crossflow velocity in filter process is 5m/s, obtains filtrate, for subsequent use;
(6) gained filtrate in step (5) is sent into receiver, when being evaporated to 65 DEG C in receiver, the clear paste of relative density 1.08, obtains clear paste, for subsequent use;
(7) by gained clear paste sodium hydroxide solution adjust ph to 6.8 in step (6), then embedding is in soda-lime glass tubular oral liquid bottle, and fill is rolled lid and is placed on 98 DEG C of conditions, sterilizing 15min, and warehouse-in is finished product, must treat hypertensive Chinese medicine oral liquid.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107029122A (en) * | 2017-03-16 | 2017-08-11 | 杨本雷 | It is a kind of to treat pharmaceutical composition of hypertension and preparation method thereof, preparation and application |
| CN107029122B8 (en) * | 2017-03-16 | 2024-06-11 | 楚雄彝族自治州彝族医药研究所 | Medicinal composition for treating hypertension and preparation method, preparation and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1528377A (en) * | 2003-09-26 | 2004-09-15 | 朱智文 | Pill for radical cure of hypertension and medicinal formual thereof |
| CN102451320A (en) * | 2010-10-27 | 2012-05-16 | 贺琴 | Traditional Chinese medicine for treating hypertension |
| CN104740353A (en) * | 2013-12-26 | 2015-07-01 | 王玉青 | Traditional Chinese medicine prescription for treatment of hypertension |
-
2015
- 2015-11-10 CN CN201510759429.3A patent/CN105194353A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1528377A (en) * | 2003-09-26 | 2004-09-15 | 朱智文 | Pill for radical cure of hypertension and medicinal formual thereof |
| CN102451320A (en) * | 2010-10-27 | 2012-05-16 | 贺琴 | Traditional Chinese medicine for treating hypertension |
| CN104740353A (en) * | 2013-12-26 | 2015-07-01 | 王玉青 | Traditional Chinese medicine prescription for treatment of hypertension |
Non-Patent Citations (2)
| Title |
|---|
| 凌沛学: "《中药学概论》", 31 August 2007, 中国轻工业出版社 * |
| 李泽华: "高血压病中医药防治的临床文献研究", 《北京中医药》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107029122A (en) * | 2017-03-16 | 2017-08-11 | 杨本雷 | It is a kind of to treat pharmaceutical composition of hypertension and preparation method thereof, preparation and application |
| CN107029122B (en) * | 2017-03-16 | 2018-05-01 | 杨本雷 | A kind of pharmaceutical composition for treating hypertension and preparation method thereof, preparation and application |
| CN107029122B8 (en) * | 2017-03-16 | 2024-06-11 | 楚雄彝族自治州彝族医药研究所 | Medicinal composition for treating hypertension and preparation method, preparation and application thereof |
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