CN105232339A - Antibacterial and durable tooth filling composite material and preparation method thereof - Google Patents

Antibacterial and durable tooth filling composite material and preparation method thereof Download PDF

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CN105232339A
CN105232339A CN 201510661293 CN201510661293A CN105232339A CN 105232339 A CN105232339 A CN 105232339A CN 201510661293 CN201510661293 CN 201510661293 CN 201510661293 A CN201510661293 A CN 201510661293A CN 105232339 A CN105232339 A CN 105232339A
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composite material
durable
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antibacterial
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金仲恩
全春兰
张帆
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苏州蔻美新材料有限公司
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Abstract

The invention discloses an antibacterial and durable tooth filling composite material and a preparation method thereof. The composite material is prepared from the following components in parts by weight: 30-40 parts of polymethyl methacrylate, 20-25 parts of hydroxyl calcium phosphate, 13-15 parts of acetoacetoxyethyl methacrylate, 3-8 parts of fimbrin, 1-3 parts of 2-thiol benzimidazole, 5-12 parts of a phase transfer agent, 12-30 parts of glycosaminoglycan, 5-10 parts of steamed bone meal, 4-8 parts of silver cyclohexylbutyrate, 3-5 parts of casein, 4-8 parts of hydroxy anisole, 3-8 parts of an antioxidant, 12-24 parts of sorbitol, 8-23 parts of benzyl alcohol and 25-45 parts of double distilled water. The composite material disclosed by the invention is capable of improving tissue compatibility and blood compatibility, and the composite material is antibacterial, capable of improving mechanical and physical properties, wear-resistant and durable to use; and the preparation method has the advantages of being simple in process, easy to operate, high in yield, low in pollution to environment and the like.

Description

一种抗菌耐用补牙复合材料及其制备方法 A composite material and its preparation method and durable dental Antibacterial

技术领域 FIELD

[0001] 本发明涉及一种抗菌耐用补牙复合材料及其制备方法。 [0001] The present invention relates to a composite material and method for preparing an antimicrobial durable fillings.

技术背景 technical background

[0002] 龋病俗称虫牙、蛀牙,是细菌性疾病,可以继发牙髓炎和根尖周炎,甚至能引起牙槽骨和颂骨炎症。 [0002] cavities known as caries, tooth decay, a bacterial disease, can be secondary pulpitis and periapical bone and even can cause inflammation of the maxilla. 如不及时治疗,病变继续发展,形成龋洞,终至牙冠完全破坏消失,其发展的最终结果是牙齿丧失。 If not treated, the lesions continue to develop, the formation of cavities, and finally to crown disappear completely destroyed, its development is the end result of tooth loss. 龋病特点是发病率高,分布广。 It is characterized by a high incidence of dental caries, wide distribution. 是口腔主要的常见病,也是人类最普遍的疾病之一,世界卫生组织已将其与肿瘤和心血管疾病并列为人类三大重点防治疾病。 Is the main common oral and one of the most common human diseases, the World Health Organization has its parallel with the cancer and cardiovascular disease is the focus of the three major human disease prevention. 1.龋齿对成人的危害:①经常造成牙根尖等部位的炎症,严重时局部肿胀;如脓液和细菌被吸收,可引起败血症或菌血症。 1. Caries harm adults: ① the sites of inflammation often results in the root apex, severe swelling; pus and bacteria such as absorption, may cause sepsis or bacteremia. ②坏牙根不能咀嚼食物;加重胃肠道负担。 ② bad root can not chew food; increase the gastrointestinal tract burden. ③对于老年人来说,严重龋坏可造成大部分或全部牙齿缺失,不利于老年人的身体健康。 ③ For the elderly, it can cause severe caries most or all missing teeth, is not conducive to the health of the elderly. 2.儿童龋齿的8大危害性:①牙体缺损,涉及多个乳磨牙时可降低咀嚼功能;②龋洞内食物残渣滞留,细菌聚集,使口腔卫生恶化,影响恒牙发生龋患乳牙根尖周炎影响继承恒牙牙胚,造成其釉质发育及正常萌出障碍乳牙因龋早失,造成恒牙间隙缩小,因间隙不足发生位置异常乳牙龋坏破损的牙冠易损伤局部的口腔黏膜组织;©乳牙龋坏严重,造成咀嚼功能降低,影响儿童的营养摄入,对生长发育造成影响;⑦乳牙龋病发展为根尖周病可作为病灶牙使机体的其他组织发生病灶感染;⑧影响美观和正确发音。 2. dental caries in children of eight major dangers: ① dental defects can reduce chewing function when multiple primary molars; ② cavities within the food residue retention, bacterial aggregation, the oral health deterioration, affecting permanent teeth primary teeth caries occur apical influence inherited permanent tooth, causing its normal eruption and enamel developmental disorders early loss of deciduous teeth due to caries, cause permanent gap narrowed, the crown because of lack of space the error occurred deciduous caries damaged easily localized oral mucosal tissue damage; © deciduous caries serious, resulting in reduced masticatory function, affect the nutritional intake of children, the impact on growth and development; ⑦ deciduous caries development periapial as a focal infection foci of other teeth so that the body tissue; ⑧ affect the appearance and the correct pronunciation. 药物治疗是在磨除龋坏的基础上,应用药物抑制龋病发展的方法,适用于恒牙尚未成洞的浅龋,乳前牙的浅、中龋洞。 Drug therapy is based on the ground in addition to caries, the method of application of drugs that inhibit the development of caries, superficial caries in permanent teeth have not yet applied to the hole, before milk teeth shallow, in cavities. 常用药物包括氨硝酸银和氟化钠等。 Commonly used drugs include ammonia silver nitrate and sodium fluoride. 对已形成实质性缺损的牙齿,充填术是目前应用最广泛且成效较好的方法,其基本过程可分为两步:先去除龋坏组织和失去支持的薄弱牙体组织,并按一定要求将窝洞制成合理的形态。 Teeth have formed a substantial defect filling technique is the most widely used and effective method better, the basic two-step process: first, the removal of carious tissue and weak tooth structure lost support, according to certain requirements the cavity shape made reasonable. 然后以充填材料填充恢复其固有形态和功能。 Then fill the filling material to recover its inherent shape and function. 充填材料有银汞合金、复合树脂等。 Filler silver amalgam, composite resins and the like. 其中银汞合金坚固、不易耗损但不够美观,复合树脂美观、接近牙齿天然的颜色,但强度不如银汞合金,易损耗,在大多数情况下,现有复合树脂材料的表面化学组成与结构很难满足上述要求,通常要采用表面改性处理,如接枝共聚,以改进其性能。 Wherein amalgam sturdy, easy to wear, but less attractive, aesthetic composite resin, the natural tooth color close, but not as strong as amalgam, subject to wear, in most cases, the surface chemical composition and structure of the conventional composite resin material is difficult to meet the above requirements, usually by surface modification, such as graft copolymerization, to improve its performance. 此外,材料还需要优异的加工成型性,易加工成需要的复杂形状的。 Further, the material needs excellent in moldability, easy processing into complex shapes needed. 所以需要研制一种既易加工成型又满足强度要求的补牙材料。 It is necessary to develop a both easy processing and dental fillings meet strength requirements.

发明内容 SUMMARY

[0003] 本发明的目的在于针对现有技术的不足,提供一种既易加工成型又满足强度要求的抗菌耐用补牙复合材料及其制备方法。 [0003] The object of the present invention is for the deficiencies of the prior art, to provide an easy processing both antibacterial and durable dental composite material and its preparation method to meet the strength requirements.

[0004] 本发明的目的是通过以下技术方案实现的:一种抗菌耐用补牙复合材料,由以下重量份配比的组分制成:聚甲基丙烯酸甲酯30-40份、羟基磷酸钙20-25份、甲基丙烯酸乙酰乙酰氧基乙酯13-15份、丝束蛋白3-8份、2-硫醇基苯骈咪唑1-3份、相转移剂5_12份、氨基葡聚糖12-30份、蒸骨粉5-10份、环己基丁酸银盐4-8份、干酪素3_5份、羟基苯甲醚4-8份、抗氧剂3-8份、山梨醇12-24份、苯甲醇8_23份、双蒸水25-45份。 [0004] The object of the present invention is achieved by the following technical solutions: A durable antimicrobial dental composite, the ratio by weight of component parts: 30-40 parts of polymethyl methacrylate, HAP 20 -25 parts of methacrylic acid, 13-15 parts of acetoacetoxyethyl methacrylate, 3-8 parts of fimbrin, 2-mercaptobenzimidazole benzimidazole 1-3 parts, parts of 5_12 phase transfer agent, aminodextran 12 -30 parts, 5-10 parts of distilled bone meal, cyclohexyl butyric acid silver salt 4-8 parts, casein 3_5 parts, parts hydroxyanisole 4-8, 3-8 parts of an antioxidant, 12-24 parts of sorbitol , 8_23 parts of benzyl alcohol, 25-45 parts of distilled water.

[0005] 所述相转移剂为正四丁基溴化铵。 [0005] The phase transfer agent is n-tetrabutylammonium bromide.

[0006] 所述抗氧剂为2,6- 二叔丁基对甲酚。 [0006] The antioxidant is butylated hydroxytoluene.

[0007] —种抗菌耐用补牙复合材料的制备方法,所述方法包括以下步骤:步骤1,按重量份称取各组分,将除甲基丙烯酸乙酰乙酰氧基乙酯和环己基丁酸银盐以外的各个组分加入混合机中,搅拌均匀后得混合物;步骤2,将混合物用超声波破碎1-2小时;步骤3,将甲基丙烯酸乙酰乙酰氧基乙酯和环己基丁酸银盐加至步骤2获得的混合物中,在温度为55-57°C、转速为500-600 rpm条件下,搅拌至混合物为均匀膏体状时即可制得补牙复合材料。 [0007] - preparing a durable antimicrobial dental composite material, said method comprising the steps of species: Step 1, parts by weight of the components weighed, the acetoacetoxyethyl methacrylate, and cyclohexyl methacrylate in addition to silver butyric acid a salt other than the individual components added to the mixer, the resulting mixture was uniformly stirred; step 2, the mixture was crushed with an ultrasonic 1-2 hours; step 3, acetoacetoxyethyl methacrylate, and cyclohexyl butyric acid silver salt of methacrylic acid step 2 was added to the mixture obtained, at a temperature of 55-57 ° C, 500-600 rpm speed of the condition, to the mixture was stirred for dental composites can be prepared as homogeneous paste-like material.

所述步骤2,超声波功率为35-45W。 Step 2, the ultrasonic power is 35-45W.

所述步骤3,搅拌速度为550-560rpm。 Step 3, stirring speed 550-560rpm.

本发明的有益效果是:本发明的复合材料提高组织相容性和血液相容性;具有抗菌性,改善提高力学、机械、物理性能,不易磨损耐用;其制备方法具有工艺简单,易操作,产率高,对环境污染小等优点。 Advantageous effects of the present invention is that: the composite material of the invention improves tissue compatibility and blood compatibility; have antibacterial properties, improved to improve the mechanical, mechanical, physical properties, easy to wear and durable; the preparation method has a simple process, easy to operate, yield, environmental pollution and other advantages.

具体实施方式 detailed description

[0008] 实施例1 [0008] Example 1

一种抗菌耐用补牙复合材料,由以下重量份配比的组分制成:聚甲基丙烯酸甲酯30-40份、羟基磷酸钙20份、甲基丙烯酸乙酰乙酰氧基乙酯13份、丝束蛋白3份、2-硫醇基苯骈咪唑1份、相转移剂5份、氨基葡聚糖12份、蒸骨粉5份、环己基丁酸银盐4份、干酪素3份、羟基苯甲醚4份、抗氧剂3份、山梨醇12份、苯甲醇8份、双蒸水25份。 An antibacterial durable dental composite, the ratio by weight of the following component parts: 30-40 parts polymethyl methacrylate, 20 parts of calcium hydroxyphosphate, methacrylic acid, acetoacetoxyethyl methacrylate 13 parts, wire fascin 3 parts of 2-mercaptobenzimidazole benzimidazole parts 1, 5 parts of phase transfer agent, 12 parts of aminodextran, 5 parts of steamed bone meal, 4-cyclohexyl butyric acid silver parts, 3 parts of casein, hydroxyphenyl ether 4 parts, 3 parts of antioxidant, 12 parts of sorbitol, 8 parts of benzyl alcohol, 25 parts of distilled water. 所述相转移剂为正四丁基溴化铵。 The phase transfer agent is n-tetrabutylammonium bromide. 所述抗氧剂为2,6- 二叔丁基对甲酚。 The antioxidant is butylated hydroxytoluene.

[0009] 其制备方法包括以下步骤:步骤1,按重量份称取各组分,将除甲基丙烯酸乙酰乙酰氧基乙酯和环己基丁酸银盐以外的各个组分加入混合机中,搅拌均匀后得混合物;步骤2,将混合物用超声波破碎1小时;步骤3,将甲基丙烯酸乙酰乙酰氧基乙酯和环己基丁酸银盐加至步骤2获得的混合物中,在温度为55°C、转速为500 rpm条件下,搅拌至混合物为均匀膏体状时即可制得补牙复合材料。 [0009] The preparation method comprises the following steps: Step 1, parts by weight by weighing the components, the respective components other than methyl methacrylate and acetoacetoxyethyl methacrylate, cyclohexyl butyric acid silver salt is added to the mixer, after stirring to obtain a homogeneous mixture; step 2, the mixture was crushed by ultrasonic wave for 1 hours; the mixture of step 3, methacrylic acid acetoacetoxyethyl methacrylate and cyclohexyl butyric acid was added to the silver salt obtained in step 2 at a temperature of 55 ° C, 500 rpm rotation speed under the condition, to the mixture is stirred to obtain a uniform when the dental composite material in paste. 所述步骤2,超声波功率为35W。 Step 2, the ultrasonic power is 35W.

[0010] 对该实施例制备得到的补牙复合材料进行检测,随机取10颗制得的补牙材料,测试结果取平均值,经检测,其抗压强度为159.94MPa,最大力为17.72KN。 [0010] Preparation of the dental composite material obtained in Example embodiment detects randomly dental material 10 obtained, the test results were averaged, tested, the compressive strength of 159.94MPa, maximum force 17.72KN. 此实验数据证明该复合材料具有良好的物理性能。 This experimental data demonstrates that the composite material has good physical properties.

[0011] 实施例2 [0011] Example 2

一种抗菌耐用补牙复合材料,由以下重量份配比的组分制成:聚甲基丙烯酸甲酯30-40份、羟基磷酸钙25份、甲基丙烯酸乙酰乙酰氧基乙酯15份、丝束蛋白8份、2-硫醇基苯骈咪唑3份、相转移剂12份、氨基葡聚糖30份、蒸骨粉10份、环己基丁酸银盐8份、干酪素5份、羟基苯甲醚8份、抗氧剂8份、山梨醇24份、苯甲醇23份、双蒸水45份。 An antibacterial durable dental composite, the ratio by weight of the following component parts: 30-40 parts polymethyl methacrylate, 25 parts of calcium hydroxyphosphate, methacrylic acid, acetoacetoxyethyl methacrylate 15 parts, wire fascin 8 parts, 2-mercaptobenzimidazole benzimidazole 3 parts, 12 parts of a phase transfer agent, 30 parts of aminodextran, steamed bone meal 10 parts, 8-cyclohexyl butyric acid silver parts, 5 parts of casein, hydroxyphenyl ether 8 parts, 8 parts of antioxidant, 24 parts sorbitol, 23 parts of benzyl alcohol, 45 parts of distilled water. 所述相转移剂为正四丁基溴化铵。 The phase transfer agent is n-tetrabutylammonium bromide. 所述抗氧剂为2,6- 二叔丁基对甲酚。 The antioxidant is butylated hydroxytoluene.

[0012] 其制备方法包括以下步骤:步骤1,按重量份称取各组分,将除甲基丙烯酸乙酰乙酰氧基乙酯和环己基丁酸银盐以外的各个组分加入混合机中,搅拌均匀后得混合物;步骤2,将混合物用超声波破碎2小时;步骤3,将甲基丙烯酸乙酰乙酰氧基乙酯和环己基丁酸银盐加至步骤2获得的混合物中,在温度为57°C、转速为600 rpm条件下,搅拌至混合物为均匀膏体状时即可制得补牙复合材料。 [0012] The preparation method comprises the following steps: Step 1, parts by weight by weighing the components, the respective components other than methyl methacrylate and acetoacetoxyethyl methacrylate, cyclohexyl butyric acid silver salt is added to the mixer, after stirring to obtain a homogeneous mixture; step 2, the mixture was disrupted by ultrasonication 2 hours; the mixture of step 3, methacrylic acid acetoacetoxyethyl methacrylate and cyclohexyl butyric acid was added to the silver salt obtained in step 2 at a temperature of 57 ° C, speed of 600 rpm under conditions of agitation to the mixture can be prepared as a dental composite material that form a uniform paste. 所述步骤2,超声波功率为45W。 Step 2, the ultrasonic power is 45W.

[0013] 对该实施例制备得到的补牙复合材料进行检测,随机取10颗制得的补牙材料,测试结果取平均值,经检测,其抗压强度为168.54MPa,最大力为18.32KN。 [0013] Preparation of the dental composite material obtained in Example embodiment detects randomly dental material 10 obtained, the test results were averaged, tested, the compressive strength of 168.54MPa, maximum force 18.32KN. 此实验数据证明该复合材料具有良好的物理性能。 This experimental data demonstrates that the composite material has good physical properties.

[0014] 实施例3 [0014] Example 3

一种抗菌耐用补牙复合材料,由以下重量份配比的组分制成:聚甲基丙烯酸甲酯30-40份、羟基磷酸钙20-25份、甲基丙烯酸乙酰乙酰氧基乙酯14份、丝束蛋白5份、2-硫醇基苯骈咪唑2份、相转移剂8份、氨基葡聚糖21份、蒸骨粉7份、环己基丁酸银盐6份、干酪素4份、羟基苯甲醚6份、抗氧剂5份、山梨醇18份、苯甲醇15份、双蒸水35份。 An antibacterial durable dental composite, the ratio by weight of the following component parts: 30-40 parts of polymethyl methacrylate, hydroxy 20-25 parts of calcium phosphate, methacrylic acid, 14 parts of acetoacetoxyethyl methacrylate , fimbrin 5 parts of 2-mercaptobenzimidazole benzimidazole 2 parts, 8 parts of a phase transfer agent, 21 parts of aminodextran, 7 parts of distilled bone meal, cyclohexyl butyric acid 6 parts of a silver salt, 4 parts of casein, hydroxyanisole 6 parts, 5 parts of antioxidant, 18 parts sorbitol, 15 parts of benzyl alcohol, 35 parts of distilled water. 所述相转移剂为正四丁基溴化铵。 The phase transfer agent is n-tetrabutylammonium bromide. 所述抗氧剂为2,6- 二叔丁基对甲酚。 The antioxidant is butylated hydroxytoluene.

[0015] 其制备方法包括以下步骤:步骤1,按重量份称取各组分,将除甲基丙烯酸乙酰乙酰氧基乙酯和环己基丁酸银盐以外的各个组分加入混合机中,搅拌均匀后得混合物;步骤2,将混合物用超声波破碎1.5小时;步骤3,将甲基丙烯酸乙酰乙酰氧基乙酯和环己基丁酸银盐加至步骤2获得的混合物中,在温度为56°C、转速为550 rpm条件下,搅拌至混合物为均匀膏体状时即可制得补牙复合材料。 [0015] The preparation method comprises the following steps: Step 1, parts by weight by weighing the components, the respective components other than methyl methacrylate and acetoacetoxyethyl methacrylate, cyclohexyl butyric acid silver salt is added to the mixer, after stirring to obtain a homogeneous mixture; step 2, the mixture was crushed with an ultrasonic 1.5 hours; the mixture of step 3, methacrylic acid acetoacetoxyethyl methacrylate and cyclohexyl butyric acid was added to the silver salt obtained in step 2 at a temperature of 56 ° C, speed of 550 rpm under conditions of agitation to the mixture can be prepared as a dental composite material that form a uniform paste. 所述步骤2,超声波功率为40W。 Step 2, the ultrasonic power is 40W.

对该实施例制备得到的补牙复合材料进行检测,随机取10颗制得的补牙材料,测试结果取平均值,经检测,其抗压强度为177.64MPa,最大力为19.92KN。 Dental materials of the dental composite material obtained in Preparation Example embodiment detects, 10 randomly obtained, the test results were averaged, tested, the compressive strength of 177.64MPa, maximum force 19.92KN. 此实验数据证明该复合材料具有良好的物理性能。 This experimental data demonstrates that the composite material has good physical properties.

[0016] 以上所述,仅是本发明的较佳实施例而已,并非对本发明作任何形式上的限制,虽然本发明已以较佳实施例揭露如上,然而并非用以限定本发明,任何熟悉本专业的技术人员,在不脱离本发明技术方案范围内,当可利用上述揭示的技术内容作出些许更动或修饰为等同变化的等效实施例,但凡是未脱离本发明技术方案的内容,依据本发明的技术实质对以上实施例所作的任何简单修改、等同变化与修饰,均仍属于本发明技术方案的范围内。 [0016] The above are only preferred embodiments of the present invention only, not limitation of the present invention in any form, although the invention has been disclosed above by the preferred embodiments, but not intended to limit the present invention, anyone familiar with Those skilled in the art, without departing from the scope of the technical solution of the present invention, when the techniques disclosed above can be utilized with some minor modifications to the content as equivalent variations or modifications equivalent embodiments, but all without departing from the technical solutions of the present invention, any simple modifications based on the technical essence of the present invention is made to the above embodiment of the embodiment, the equivalent changes and modifications, provided they fall within the scope of the present invention.

Claims (6)

  1. 1.一种抗菌耐用补牙复合材料,其特征在于,由以下重量份配比的组分制成:聚甲基丙烯酸甲酯30-40份、羟基磷酸钙20-25份、甲基丙烯酸乙酰乙酰氧基乙酯13-15份、丝束蛋白3-8份、2-硫醇基苯骈咪唑1-3份、相转移剂5-12份、氨基葡聚糖12-30份、蒸骨粉5-10份、环己基丁酸银盐4-8份、干酪素3-5份、羟基苯甲醚4-8份、抗氧剂3_8份、山梨醇12-24份、苯甲醇8-23份、双蒸水25-45份。 A durable antimicrobial dental composite material, characterized in that the ratio formed by the following parts by weight of component: polymethyl methacrylate 30-40 parts, 20-25 parts of calcium hydroxyphosphate, acetoacetoxyethyl methacrylate, 13-15 parts ethyl group, fimbrin 3-8 parts of 2-mercaptobenzimidazole benzimidazole parts 1-3, 5-12 parts of a phase transfer agent, 12-30 parts of aminodextran, steamed bone meal 5 -10 parts, cyclohexyl butyric acid silver parts 4-8, 3-5 parts of casein, hydroxy anisole 4-8 parts of an antioxidant 3_8 parts, 12-24 parts of sorbitol, benzyl alcohol, 8-23 parts , 25-45 parts of distilled water.
  2. 2.根据权利要求1所述的一种抗菌耐用补牙复合材料,其特征在于:所述相转移剂为正四丁基溴化铵。 2. An antibacterial durable dental composite material according to claim 1, wherein: said phase transfer agent is n-tetrabutylammonium bromide.
  3. 3.根据权利要求1所述的一种抗菌耐用补牙复合材料,其特征在于:所述抗氧剂为2,6-二叔丁基对甲酚。 An antimicrobial according to claim 1 and durable dental composite as claimed in claim, wherein: the antioxidant is butylated hydroxytoluene.
  4. 4.权利要求1-3任一项所述的一种抗菌耐用补牙复合材料的制备方法,其特征在于,所述方法包括以下步骤:步骤1,按重量份称取各组分,将除甲基丙烯酸乙酰乙酰氧基乙酯和环己基丁酸银盐以外的各个组分加入混合机中,搅拌均匀后得混合物;步骤2,将混合物用超声波破碎1-2小时;步骤3,将甲基丙烯酸乙酰乙酰氧基乙酯和环己基丁酸银盐加至步骤2获得的混合物中,在温度为55-57°C、转速为500-600 rpm条件下,搅拌至混合物为均匀膏体状时即可制得补牙复合材料。 An antimicrobial according durable dental composite material prepared according to any of claims 1-3, characterized in that the method comprises the following steps: Step 1, parts by weight of the components weighed, in addition to the A acrylate, acetoacetoxyethyl methacrylate group and the respective components other than silver-cyclohexyl butyric acid added to the mixer, the resulting mixture was uniformly stirred; step 2, the mixture was crushed with an ultrasonic 1-2 hours; step 3, methyl acetoacetoxyethyl methacrylate mixture of acrylic acid and cyclohexyl butyric acid was added to the silver salt obtained in step 2, at a temperature of 55-57 ° C, speed of 500-600 rpm conditions, when the mixture is stirred until a uniform paste-like can be prepared dental composites.
  5. 5.根据权利要求4所述的一种抗菌耐用补牙复合材料的制备方法,其特征在于:所述步骤2,超声波功率为35-45W。 The method for preparing an antimicrobial dental 4 durable composite material as claimed in claim, wherein: the step 2, the ultrasonic power is 35-45W.
  6. 6.根据权利要求4所述的一种抗菌耐用补牙复合材料的制备方法,其特征在于:所述步骤3,搅拌速度为550-560rpm。 6. An antimicrobial preparation durable dental composite material 4 according to claim, wherein: said step 3, the stirring speed of 550-560rpm.
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* Cited by examiner, † Cited by third party
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CN105832566A (en) * 2016-05-24 2016-08-10 苏州蔻美新材料有限公司 Preparation method of resin material used for dental repair
CN105832565A (en) * 2016-05-24 2016-08-10 苏州蔻美新材料有限公司 Preparation method of low-shrinkage dental filling resin materials
CN105853240A (en) * 2016-05-24 2016-08-17 苏州蔻美新材料有限公司 Preparation method of antibacterial tooth repair material
CN105997527A (en) * 2016-05-30 2016-10-12 苏州蔻美新材料有限公司 Preparation method of antibacterial and wear-resistant material for filling teeth
CN106038321A (en) * 2016-05-30 2016-10-26 苏州蔻美新材料有限公司 Preparation method of tooth filling composite material

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CN101516319A (en) * 2006-09-13 2009-08-26 3M创新有限公司 Dental compositions including organogelators, products, and methods
CN104887535A (en) * 2015-05-26 2015-09-09 中国科学院宁波材料技术与工程研究所 Preparation method of low-volume-shrinkage antibacterial dental resin composite material
CN104941006A (en) * 2015-06-30 2015-09-30 苏州佑君环境科技有限公司 Preparation method of composite material for joint prosthesis

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Publication number Priority date Publication date Assignee Title
CN101014297A (en) * 2004-08-06 2007-08-08 彭特恩临床科技有限公司 Dental filling material
CN101516319A (en) * 2006-09-13 2009-08-26 3M创新有限公司 Dental compositions including organogelators, products, and methods
CN104887535A (en) * 2015-05-26 2015-09-09 中国科学院宁波材料技术与工程研究所 Preparation method of low-volume-shrinkage antibacterial dental resin composite material
CN104941006A (en) * 2015-06-30 2015-09-30 苏州佑君环境科技有限公司 Preparation method of composite material for joint prosthesis

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105832566A (en) * 2016-05-24 2016-08-10 苏州蔻美新材料有限公司 Preparation method of resin material used for dental repair
CN105832565A (en) * 2016-05-24 2016-08-10 苏州蔻美新材料有限公司 Preparation method of low-shrinkage dental filling resin materials
CN105853240A (en) * 2016-05-24 2016-08-17 苏州蔻美新材料有限公司 Preparation method of antibacterial tooth repair material
CN105997527A (en) * 2016-05-30 2016-10-12 苏州蔻美新材料有限公司 Preparation method of antibacterial and wear-resistant material for filling teeth
CN106038321A (en) * 2016-05-30 2016-10-26 苏州蔻美新材料有限公司 Preparation method of tooth filling composite material

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