CN105213532A - A kind of Chinese medicine oral liquid and preparation method for the treatment of lumbar vertebra pain - Google Patents
A kind of Chinese medicine oral liquid and preparation method for the treatment of lumbar vertebra pain Download PDFInfo
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Abstract
The present invention discloses a kind of Chinese medicine oral liquid and preparation method for the treatment of lumbar vertebra pain, is made up of following raw material: Radix Angelicae Sinensis 10-14 part, Radix Astragali 38-42 part, Herba Pyrolae 18-22 part, Eupolyphaga Seu Steleophaga 10-14 part, Herba Taxilli 28-32 part, Fructus Chaenomelis 18-22 part, Rhizoma Chuanxiong 13-17 part, Caulis Spatholobi 28-32 part, Radix Clematidis 18-22 part, Ramulus Cinnamomi 5-9 part, Rhizoma Cibotii 28-32 part, Radix Aconiti Lateralis Preparata 3-7 part, Radix Achyranthis Bidentatae 18-22 part, Herba Asari 2-6 part, Radix Glycyrrhizae 4-8 part.The present invention has effect of blood stasis and smoothing collaterals alive, bone and muscle strengthening, the kidney invigorating cold relieving, and be a kind of safe and reliable, without any side effects, effective ingredient utilization rate is high, the Chinese medicine composition of instant effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine oral liquid for the treatment of lumbar vertebra pain, belong to the field of Chinese medicines.
Background technology
Lumbar vertebra pain common are waist hyperosteogeny owing to comparing, bony spur, intervertebral disc prolapse, hyperosteogeny, spinal canal stenosis, waist is fractured, tumor in vertebral canal, waist acute and chronic wound or strain, lumbar muscle strain, the flank pain that the diseases such as ankylosing spondylitis cause, causes the reason of lumbar vertebra pain a lot, about has tens of kinds, compare and common are waist hyperosteogeny, bony spur, intervertebral disc prolapse, hyperosteogeny, spinal canal stenosis, waist is fractured, tumor in vertebral canal, waist acute and chronic wound or strain, lumbar muscle strain, ankylosing spondylitis etc., in traditional view, chronic back pain after disease factor is got rid of in general inspection is often regarded " lumbar muscle strain ", in fact, what have 4 one-tenth lumbago persons to suffer from is Chronic compartment syndrome, but perplex by lumbago for a long time owing to can not get symptomatic treatment, many patients have the lumbago of long period, someone even pain that what within 50 years, also not to be known is sick, the trend that becomes younger of lumbago also clearly, somebody has just suffered from this disease for 18 years old, lower back is the position that human body is firmly maximum, provide support for human body and protect spinal column, to the long-term people lacked exercise in office's sitting, or because of the people that job demand is stood for a long time, long-time maintenance position or posture too of a specified duration, just easily cause the pain of lower back and cause lumbosacral region Chronic compartment syndrome, also accumulation morbidity after repeated injury is had plenty of.A lot of chronic back pain patient is relevant with Chronic compartment syndrome, and reason may be that under the intrinsic pressure rising of bone fixation causes fascia thoracolumbalis, gap disappears, and muscle blood flow amount declines, loose fatty tissue degeneration.Due to this infringement, cause patient and walk more, sit or drowsiness more, all can pain in the lumbar region, namely keep a kind of posture easily to produce pain in the lumbar region for a long time.This is the important clinical feature of chronic bone fixation syndrome, the western medical treatment Main Means taked this disease at present takes antibiotic, but western medicine is temporary transient symptom management mostly, and it is harmful unhelpful to take too many antibiotic, because abuse of antibiotics may cause bottleneck throat normal flora to be lacked of proper care, and resistance can be caused to strengthen, immune function of human body goes down, and causes Relapse rate difficulty more.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine oral liquid for the treatment of lumbar vertebra pain, it has effect of blood stasis and smoothing collaterals alive, bone and muscle strengthening, the kidney invigorating cold relieving.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine oral liquid for lumbar vertebra pain, be made up of following raw material: Radix Angelicae Sinensis 10-14 part, Radix Astragali 38-42 part, Herba Pyrolae 18-22 part, Eupolyphaga Seu Steleophaga 10-14 part, Herba Taxilli 28-32 part, Fructus Chaenomelis 18-22 part, Rhizoma Chuanxiong 13-17 part, Caulis Spatholobi 28-32 part, Radix Clematidis 18-22 part, Ramulus Cinnamomi 5-9 part, Rhizoma Cibotii 28-32 part, Radix Aconiti Lateralis Preparata 3-7 part, Radix Achyranthis Bidentatae 18-22 part, Herba Asari 2-6 part, Radix Glycyrrhizae 4-8 part.
Preferably, each parts by weight of raw materials is: Radix Angelicae Sinensis 12 parts, the Radix Astragali 40 parts, Herba Pyrolae 20 parts, Eupolyphaga Seu Steleophaga 12 parts, Herba Taxilli 30 parts, Fructus Chaenomelis 20 parts, Rhizoma Chuanxiong 15 parts, Caulis Spatholobi 30 parts, Radix Clematidis 20 parts, Ramulus Cinnamomi 7 parts, Rhizoma Cibotii 30 parts, Radix Aconiti Lateralis Preparata 5 parts, Radix Achyranthis Bidentatae 20 parts, Herba Asari 4 parts, 6 parts, Radix Glycyrrhizae.
Pharmacological action:
Radix Angelicae Sinensis: nature and flavor with return through sweet, acrid, warm; Return liver, the heart, spleen channel, function with cure mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation; For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores; Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow; For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
The Radix Astragali: nature and flavor with return through: sweet, temperature; Return lung, spleen channel, function with cure mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation; Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Herba Pyrolae: nature and flavor: sweetness and bitterness, temperature; Gui Jing: enter lung meridian, stomach warp, Liver Channel, kidney channel; Function: energy tonify deficiency, kidney tonifying, expelling wind and removing dampness, promoting blood flow to regulate menstruation, the kidney invigorating bone strengthening, cough-relieving, hemostasis; Cure mainly: main lumbago due to renal deficiency, rheumatic arthralgia, soft, the new chronic cough of muscles and bones flaccidity are coughed, spit blood, epistaxis, metrorrhagia, traumatic hemorrhage.
Eupolyphaga Seu Steleophaga: nature and flavor with return through: salty, cold; Slightly poisonous; Return Liver Channel, function with cure mainly: removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones; For injured bone, blood stasis amenorrhea ， mass in the abdomen mass in the abdomen.
Herba Taxilli: nature and flavor with return through bitter, sweet, flat; Return liver, kidney channel, function with cure mainly: invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit; For rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, metrorrhagia through many, blood leaking in gestation, frequent fetal movement; Hypertension.
Fructus Chaenomelis: nature and flavor with return through: acid, temperature; Return liver, spleen channel, function with cure mainly: suppressing the hyperactive liver relaxing muscles and tendons, stomach function regulating removing dampness; For arthralgia chiefly caused by damp pathogen contracture, the heavy pain of waist knee joint acid, convulsion of vomiting and diarrhoea, beriberi edema.
Rhizoma Chuanxiong: nature and flavor with return through: pungent, temperature; Return liver, gallbladder, pericardium channel, function with cure mainly: blood-activating and qi-promoting, wind-expelling pain-stopping; For menoxenia, amenorrhea dysmenorrhea ， mass in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Caulis Spatholobi: nature and flavor with return through: bitter, sweet, temperature; Return liver, kidney channel, function with cure mainly: enrich blood, invigorate blood circulation, dredging collateral; For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.
Radix Clematidis: nature and flavor with return through: pungent, salty, temperature; Return urinary bladder channel, function with cure mainly: expelling wind and removing dampness, removing obstruction in the collateral to relieve pain; For rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness, bone is choked with sobs larynx.
Ramulus Cinnamomi: nature and flavor with return through acrid, sweet, warm; GUIXIN, lung, urinary bladder channel, function with cure mainly: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins; For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Rhizoma Cibotii: nature and flavor with return through: bitter, sweet, temperature; Return liver, kidney channel, function with cure mainly: invigorating the liver and kidney, strong spinal column, wind-damp dispelling; For soreness of the waist and knees, weakness of the lower extremities, rheumatic arthralgia.
Radix Aconiti Lateralis Preparata: meridian distribution of property and flavor: pungent, sweet is warm greatly; Poisonous; GUIXIN, kidney, spleen channel; Function: recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, dispersing cold for relieving pain; " for recuperating depleted YANG and rescuing the patient from collapse first product medicine "; Cure mainly: for excess of YIN gram sun, loss of YANG due to profuse perspiration, vomiting and diarrhoea, it is inverse to faint, cold extremities faint pulse, trusted subordinate's cold type of pain, cold-dysentery, beriberi edema, anemofrigid-damp arthralgia, cold womb, and deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, the disease of carbuncle of yin nature skin infection and all chronic diseaseses.
Radix Achyranthis Bidentatae: nature and flavor with return through: bitter, sour, flat; Return liver, kidney channel, function with cure mainly: invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards; For soreness of waist and knee joint, muscles and bones is unable, amenorrhea note of the ancient Chinese abdominal mass, dizziness due to hyperactivity of liver-YANG.
Herba Asari: nature and flavor with return through: pungent, temperature; GUIXIN, lung, kidney channel, function with cure mainly: expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention; For anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.
Radix Glycyrrhizae: nature and flavor with return through: sweet, flat; GUIXIN, lung, spleen, stomach warp, function with cure mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription; For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Another technical problem to be solved by this invention is to provide a kind of preparation method preparing above-mentioned Chinese medicine oral liquid.
Another technical problem to be solved by this invention is achieved through the following technical solutions:
Treat a preparation method for the Chinese medicine oral liquid of lumbar vertebra pain, be prepared from by following methods:
(1) raw material Radix Angelicae Sinensis, the Radix Astragali, Herba Pyrolae, Eupolyphaga Seu Steleophaga, Herba Taxilli, Fructus Chaenomelis, Rhizoma Chuanxiong, Caulis Spatholobi, Radix Clematidis, Ramulus Cinnamomi, Rhizoma Cibotii, Radix Achyranthis Bidentatae, Herba Asari, Radix Glycyrrhizae cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight and 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight and 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) raw material Radix Aconiti Lateralis Preparata cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(3) admixing medical solutions is obtained by putting into high speed centrifuge centrifugalize under rotating speed is 10000-30000r/min after gained filtrate mixing in gained filtrate in step (1) and step (2), then the ethanol of 60-90% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-500nm, and the pressure limit crossed in filter fly is 0.05-0.7MPa, and the scope of the crossflow velocity in filter process is 1-6m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, in receiver, be evaporated to the extractum of relative density 1.10-1.15 during 60-70 DEG C, obtain extractum, for subsequent use;
(6) by gained clear paste in step (5) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in clean vial again, steam sterilization 25-35min sterilizing under 100-103 DEG C of condition after lid is rolled in fill, and warehouse-in is finished product, must treat the Chinese medicine oral liquid of lumbar vertebra pain.
Preferably, a kind of preparation method for the treatment of the Chinese medicine oral liquid of lumbar vertebra pain, is prepared from by following methods:
(1) raw material Radix Angelicae Sinensis, the Radix Astragali, Herba Pyrolae, Eupolyphaga Seu Steleophaga, Herba Taxilli, Fructus Chaenomelis, Rhizoma Chuanxiong, Caulis Spatholobi, Radix Clematidis, Ramulus Cinnamomi, Rhizoma Cibotii, Radix Achyranthis Bidentatae, Herba Asari, Radix Glycyrrhizae cold water soak 30 minutes is got, then put into decocting machine and decoct with water twice, first time adds the soak by water 1 hour of above-mentioned raw material weight and 8 times, second time adds the soak by water 1 hour of above-mentioned raw materials weight and 6 times, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) get raw material Radix Aconiti Lateralis Preparata cold water soak 30 minutes, then put into decocting machine and decoct with water twice, first time adds the soak by water 1 hour of above-mentioned raw material weight 8 times, second time adds the soak by water 1 hour of above-mentioned raw materials weight 6 times, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(3) admixing medical solutions is obtained by putting into high speed centrifuge centrifugalize under rotating speed is 18000r/min after gained filtrate mixing in gained filtrate in step (1) and step (2), then the ethanol of 80% is added by volume, leave standstill 48 hours, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size of the filter membrane of described ultrafilter is 40nm, and the pressure limit crossed in filter fly is 0.3MPa, and the scope of the crossflow velocity in filter process is 3.5m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, when being evaporated to 60 DEG C in receiver, the extractum of relative density 1.10, obtains extractum, for subsequent use;
(6) by gained clear paste sodium hydroxide solution adjust ph to 7.0 in step (5), then embedding is in clean vial, and steam sterilization 35min sterilizing under 100 DEG C of conditions after lid is rolled in fill, and warehouse-in is finished product, must treat the Chinese medicine oral liquid of lumbar vertebra pain.
Beneficial effect: the present invention has effect of blood stasis and smoothing collaterals alive, bone and muscle strengthening, the kidney invigorating cold relieving, be a kind of safe and reliable, without any side effects, effective ingredient utilization rate is high, the Chinese medicine composition of instant effect.
The present invention adopts pure Chinese medicine to be raw material, according to pathogenic factor and the Clinical symptoms of lumbar vertebra pain, under instruction of Chinese Medicine theory, carry out prescription be prepared from the basis not being raw-material activity, show through clinical efficacy, this medicine has definite curative effect to lumbar vertebra pain, is the ideal treatment medication of a kind of lumbar vertebra pain patient.
Model case
Case 1: Mrs Shen, 40 years old, medical history: waist and right side lower limb pain under patient main suit, numb 6 months, increase the weight of more than 10 days, patient went out lower waist and right side lower limb pain without obvious inducement before 6 months, the sense of waist buttocks falling inflation, exacerbation of symptoms when bending over and walk, takes Drug therapy of the present invention one week, and after treatment, the conscious lumbago of patient and right side lower limb pain obviously reduce, after taking two courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Case 2: Mrs Cheng, 65 years old, medical history: patient main suit suffers from lumbar vertebra pain 1 year, recently the symptoms such as pain 1 day are felt on rear side of waist and right lateral thigh, take Drug therapy of the present invention one week, after treatment, the conscious lumbago of patient and right side lower limb pain obviously reduce, and after taking two courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Case 3: Mrs Li, 48 years old, medical history: patient main suit's lumbago 5 days, night increased the weight of, and takes Drug therapy of the present invention one week, and after treatment, the conscious lumbago of patient obviously alleviates, and after taking a course for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Case 4: Mrs Zhan, 74 years old, medical history: more than patient's lumbago first quarter moon, took Drug therapy of the present invention one week, and after treatment, the conscious lumbago of patient obviously alleviates, and after taking a course for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and followed up a case by regular visits to 1 year without recurrence.
Case 5: Mr. Tang, 57 years old, suffers from lumbar spondylosis 5 years, recently again recur, flank pain unbearably, can not bend and stretch, can't take care of oneself, examine, main suit: lumbago 3 days, night increases the weight of, take Drug therapy of the present invention one week, after treatment, the conscious lumbago of patient obviously alleviates, and after taking three courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Case 6: Mr. Song, 45 years old, suffers from lumbar spondylosis 3 years, recently again recur, flank pain unbearably, can not bend and stretch, can't take care of oneself, examine, main suit: lumbago 5 days, night increases the weight of, take Drug therapy of the present invention one week, after treatment, the conscious lumbago of patient obviously alleviates, and after taking three courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Clinical data
Physical data: lumbar spondylosis patient 50 example, wherein male 22 example, women 28 example; Age 19-75 year.
Diagnostic criteria: 1. lumbago: the lumbar spondylosis patient of more than 95% has this symptom; 2. lower limb radiating pain: this disease appears in 80% patient, lumbago of being everlasting alleviates or disappears rear appearance; 3. numbness of lower limbs, creeping chill and intermittent claudication: numbness of lower limbs is many to occur together with pain, and small number of patients can show as simple numbness, has the conscious lower limb of small number of patients to feel cold, send out cool; 4. cauda equina nerve symptom: be mainly seen in central type vertebral pulp and deviate from disease, more rare clinically.
Therapeutic Method: take oral liquid of the present invention, every day 2 times, each 40ml 15 days was 1 course for the treatment of.
Curative effect determinate standard: 1. fully recover: conscious pain disappears, and function recovers normal substantially, check that pressure pain point disappears, swelling disappears, and can work; 2. effective: conscious pain disappears substantially, former pressure pain point alleviates, and swelling disappears substantially, and function is improved, and life can be taken care of oneself; 3. effective: conscious pain relief, former pressure pain point or swelling alleviate, and activity is still influenced; 4. invalid: pain does not subtract, sign as usual or increase the weight of.
Therapeutic outcome: by this side treatment 50 example, wherein clinical recovery 40 example, effective 7 examples, effective 3 examples, invalid 0 example, total effective rate is 100%.
Detailed description of the invention
Embodiment 1
The present invention treats the preparation of lumbar vertebra pain Chinese medicine oral liquid, and the weight portion of each raw material is: Radix Angelicae Sinensis 14 parts, the Radix Astragali 42 parts, Herba Pyrolae 22 parts, Eupolyphaga Seu Steleophaga 14 parts, Herba Taxilli 32 parts, Fructus Chaenomelis 22 parts, Rhizoma Chuanxiong 17 parts, Caulis Spatholobi 32 parts, Radix Clematidis 22 parts, Ramulus Cinnamomi 9 parts, Rhizoma Cibotii 32 parts, Radix Aconiti Lateralis Preparata 7 parts, Radix Achyranthis Bidentatae 22 parts, Herba Asari 6 parts, 8 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) raw material Radix Angelicae Sinensis, the Radix Astragali, Herba Pyrolae, Eupolyphaga Seu Steleophaga, Herba Taxilli, Fructus Chaenomelis, Rhizoma Chuanxiong, Caulis Spatholobi, Radix Clematidis, Ramulus Cinnamomi, Rhizoma Cibotii, Radix Achyranthis Bidentatae, Herba Asari, Radix Glycyrrhizae cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight and 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight and 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) raw material Radix Aconiti Lateralis Preparata cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(3) admixing medical solutions is obtained by putting into high speed centrifuge centrifugalize under rotating speed is 10000-30000r/min after gained filtrate mixing in gained filtrate in step (1) and step (2), then the ethanol of 60-90% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-500nm, and the pressure limit crossed in filter fly is 0.05-0.7MPa, and the scope of the crossflow velocity in filter process is 1-6m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, in receiver, be evaporated to the extractum of relative density 1.10-1.15 during 60-70 DEG C, obtain extractum, for subsequent use;
(6) by gained clear paste in step (5) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in clean vial again, steam sterilization 25-35min sterilizing under 100-103 DEG C of condition after lid is rolled in fill, and warehouse-in is finished product, must treat the Chinese medicine oral liquid of lumbar vertebra pain.Usage: oral, every day 2 times, each 40ml.
Embodiment 2
The present invention treats the preparation of lumbar vertebra pain Chinese medicine oral liquid, and the weight portion of each raw material is: Radix Angelicae Sinensis 12 parts, the Radix Astragali 40 parts, Herba Pyrolae 20 parts, Eupolyphaga Seu Steleophaga 12 parts, Herba Taxilli 30 parts, Fructus Chaenomelis 20 parts, Rhizoma Chuanxiong 15 parts, Caulis Spatholobi 30 parts, Radix Clematidis 20 parts, Ramulus Cinnamomi 7 parts, Rhizoma Cibotii 30 parts, Radix Aconiti Lateralis Preparata 5 parts, Radix Achyranthis Bidentatae 20 parts, Herba Asari 4 parts, 6 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) raw material Radix Angelicae Sinensis, the Radix Astragali, Herba Pyrolae, Eupolyphaga Seu Steleophaga, Herba Taxilli, Fructus Chaenomelis, Rhizoma Chuanxiong, Caulis Spatholobi, Radix Clematidis, Ramulus Cinnamomi, Rhizoma Cibotii, Radix Achyranthis Bidentatae, Herba Asari, Radix Glycyrrhizae cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight and 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight and 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) raw material Radix Aconiti Lateralis Preparata cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(3) admixing medical solutions is obtained by putting into high speed centrifuge centrifugalize under rotating speed is 10000-30000r/min after gained filtrate mixing in gained filtrate in step (1) and step (2), then the ethanol of 60-90% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-500nm, and the pressure limit crossed in filter fly is 0.05-0.7MPa, and the scope of the crossflow velocity in filter process is 1-6m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, in receiver, be evaporated to the extractum of relative density 1.10-1.15 during 60-70 DEG C, obtain extractum, for subsequent use;
(6) by gained clear paste in step (5) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in clean vial again, steam sterilization 25-35min sterilizing under 100-103 DEG C of condition after lid is rolled in fill, and warehouse-in is finished product, must treat the Chinese medicine oral liquid of lumbar vertebra pain.
Usage: oral, every day 2 times, each 40ml.
Embodiment 3
The present invention treats the preparation of lumbar vertebra pain Chinese medicine oral liquid, and the weight portion of each raw material is: Radix Angelicae Sinensis 10 parts, the Radix Astragali 38 parts, Herba Pyrolae 18 parts, Eupolyphaga Seu Steleophaga 10 parts, Herba Taxilli 28 parts, Fructus Chaenomelis 18 parts, Rhizoma Chuanxiong 13 parts, Caulis Spatholobi 28 parts, Radix Clematidis 18 parts, Ramulus Cinnamomi 5 parts, Rhizoma Cibotii 28 parts, Radix Aconiti Lateralis Preparata 3 parts, Radix Achyranthis Bidentatae 18 parts, Herba Asari 2 parts, 4 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) raw material Radix Angelicae Sinensis, the Radix Astragali, Herba Pyrolae, Eupolyphaga Seu Steleophaga, Herba Taxilli, Fructus Chaenomelis, Rhizoma Chuanxiong, Caulis Spatholobi, Radix Clematidis, Ramulus Cinnamomi, Rhizoma Cibotii, Radix Achyranthis Bidentatae, Herba Asari, Radix Glycyrrhizae cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight and 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight and 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) raw material Radix Aconiti Lateralis Preparata cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(3) admixing medical solutions is obtained by putting into high speed centrifuge centrifugalize under rotating speed is 10000-30000r/min after gained filtrate mixing in gained filtrate in step (1) and step (2), then the ethanol of 60-90% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-500nm, and the pressure limit crossed in filter fly is 0.05-0.7MPa, and the scope of the crossflow velocity in filter process is 1-6m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, in receiver, be evaporated to the extractum of relative density 1.10-1.15 during 60-70 DEG C, obtain extractum, for subsequent use;
(6) by gained clear paste in step (5) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in clean vial again, steam sterilization 25-35min sterilizing under 100-103 DEG C of condition after lid is rolled in fill, and warehouse-in is finished product, must treat the Chinese medicine oral liquid of lumbar vertebra pain.Usage: oral, every day 2 times, each 40ml.
Claims (6)
1. treat a Chinese medicine oral liquid for lumbar vertebra pain, it is characterized in that: be made up of following raw material: Radix Angelicae Sinensis 10-14 part, Radix Astragali 38-42 part, Herba Pyrolae 18-22 part, Eupolyphaga Seu Steleophaga 10-14 part, Herba Taxilli 28-32 part, Fructus Chaenomelis 18-22 part, Rhizoma Chuanxiong 13-17 part, Caulis Spatholobi 28-32 part, Radix Clematidis 18-22 part, Ramulus Cinnamomi 5-9 part, Rhizoma Cibotii 28-32 part, Radix Aconiti Lateralis Preparata 3-7 part, Radix Achyranthis Bidentatae 18-22 part, Herba Asari 2-6 part, Radix Glycyrrhizae 4-8 part.
2. a kind of Chinese medicine oral liquid for the treatment of lumbar vertebra pain according to claim 1, is characterized in that: the weight portion of each raw material is: Radix Angelicae Sinensis 12 parts, the Radix Astragali 40 parts, Herba Pyrolae 20 parts, Eupolyphaga Seu Steleophaga 12 parts, Herba Taxilli 30 parts, Fructus Chaenomelis 20 parts, Rhizoma Chuanxiong 15 parts, Caulis Spatholobi 30 parts, Radix Clematidis 20 parts, Ramulus Cinnamomi 7 parts, Rhizoma Cibotii 30 parts, Radix Aconiti Lateralis Preparata 5 parts, Radix Achyranthis Bidentatae 20 parts, Herba Asari 4 parts, 6 parts, Radix Glycyrrhizae.
3. a kind of Chinese medicine oral liquid for the treatment of lumbar vertebra pain according to claim 1, is characterized in that: the weight portion of each raw material is: Radix Angelicae Sinensis 14 parts, the Radix Astragali 42 parts, Herba Pyrolae 22 parts, Eupolyphaga Seu Steleophaga 14 parts, Herba Taxilli 32 parts, Fructus Chaenomelis 22 parts, Rhizoma Chuanxiong 17 parts, Caulis Spatholobi 32 parts, Radix Clematidis 22 parts, Ramulus Cinnamomi 9 parts, Rhizoma Cibotii 32 parts, Radix Aconiti Lateralis Preparata 7 parts, Radix Achyranthis Bidentatae 22 parts, Herba Asari 6 parts, 8 parts, Radix Glycyrrhizae.
4. a kind of Chinese medicine oral liquid for the treatment of lumbar vertebra pain according to claim 1, is characterized in that: the weight portion of each raw material is: Radix Angelicae Sinensis 10 parts, the Radix Astragali 38 parts, Herba Pyrolae 18 parts, Eupolyphaga Seu Steleophaga 10 parts, Herba Taxilli 28 parts, Fructus Chaenomelis 18 parts, Rhizoma Chuanxiong 13 parts, Caulis Spatholobi 28 parts, Radix Clematidis 18 parts, Ramulus Cinnamomi 5 parts, Rhizoma Cibotii 28 parts, Radix Aconiti Lateralis Preparata 3 parts, Radix Achyranthis Bidentatae 18 parts, Herba Asari 2 parts, 4 parts, Radix Glycyrrhizae.
5. a kind of preparation method for the treatment of the Chinese medicine oral liquid of lumbar vertebra pain according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) raw material Radix Angelicae Sinensis, the Radix Astragali, Herba Pyrolae, Eupolyphaga Seu Steleophaga, Herba Taxilli, Fructus Chaenomelis, Rhizoma Chuanxiong, Caulis Spatholobi, Radix Clematidis, Ramulus Cinnamomi, Rhizoma Cibotii, Radix Achyranthis Bidentatae, Herba Asari, Radix Glycyrrhizae cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight and 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight and 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) raw material Radix Aconiti Lateralis Preparata cold water soak 10-30 minute is got, then put into decocting machine and decoct with water twice, first time adds above-mentioned raw material weight 6-10 soak by water 1-2 hour doubly, second time adds above-mentioned raw materials weight 5-8 soak by water 1-2 hour doubly, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(3) admixing medical solutions is obtained by putting into high speed centrifuge centrifugalize under rotating speed is 10000-30000r/min after gained filtrate mixing in gained filtrate in step (1) and step (2), then the ethanol of 60-90% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-500nm, and the pressure limit crossed in filter fly is 0.05-0.7MPa, and the scope of the crossflow velocity in filter process is 1-6m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, in receiver, be evaporated to the extractum of relative density 1.10-1.15 during 60-70 DEG C, obtain extractum, for subsequent use;
(6) by gained clear paste in step (5) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in clean vial again, steam sterilization 25-35min sterilizing under 100-103 DEG C of condition after lid is rolled in fill, and warehouse-in is finished product, must treat the Chinese medicine oral liquid of lumbar vertebra pain.
6. a kind of preparation method for the treatment of the Chinese medicine oral liquid of lumbar vertebra pain according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) raw material Radix Angelicae Sinensis, the Radix Astragali, Herba Pyrolae, Eupolyphaga Seu Steleophaga, Herba Taxilli, Fructus Chaenomelis, Rhizoma Chuanxiong, Caulis Spatholobi, Radix Clematidis, Ramulus Cinnamomi, Rhizoma Cibotii, Radix Achyranthis Bidentatae, Herba Asari, Radix Glycyrrhizae cold water soak 30 minutes is got, then put into decocting machine and decoct with water twice, first time adds the soak by water 1 hour of above-mentioned raw material weight and 8 times, second time adds the soak by water 1 hour of above-mentioned raw materials weight and 6 times, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) get raw material Radix Aconiti Lateralis Preparata cold water soak 30 minutes, then put into decocting machine and decoct with water twice, first time adds the soak by water 1 hour of above-mentioned raw material weight 8 times, second time adds the soak by water 1 hour of above-mentioned raw materials weight 6 times, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(3) admixing medical solutions is obtained by putting into high speed centrifuge centrifugalize under rotating speed is 18000r/min after gained filtrate mixing in gained filtrate in step (1) and step (2), then the ethanol of 80% is added by volume, leave standstill 48 hours, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size of the filter membrane of described ultrafilter is 40nm, and the pressure limit crossed in filter fly is 0.3MPa, and the scope of the crossflow velocity in filter process is 3.5m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, when being evaporated to 60 DEG C in receiver, the extractum of relative density 1.10, obtains extractum, for subsequent use;
(6) by gained clear paste sodium hydroxide solution adjust ph to 7.0 in step (5), then embedding is in clean vial, and steam sterilization 35min sterilizing under 100 DEG C of conditions after lid is rolled in fill, and warehouse-in is finished product, must treat the Chinese medicine oral liquid of lumbar vertebra pain.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106344882A (en) * | 2016-11-11 | 2017-01-25 | 东莞市百替生物科技有限公司 | Chinese herb preparation for treating rheumatic lumbar pain and preparation method |
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| CN1400007A (en) * | 2002-06-10 | 2003-03-05 | 郭好建 | Oral Chinese medicine for curing osteoarthropathy |
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