CN105194412A - Traditional Chinese medicine composition for promoting insulin secretion and reducing blood glucose of patient suffering from diabetes - Google Patents
Traditional Chinese medicine composition for promoting insulin secretion and reducing blood glucose of patient suffering from diabetes Download PDFInfo
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Abstract
The invention relates to traditional Chinese medicine composition for promoting insulin secretion and reducing blood glucose of a patient suffering from diabetes. The traditional Chinese medicine composition is prepared from active ingredients with dissolution force as follows: oyster, Chinese soapberry fruits, root-bark of monkshoodvine, all-grass or roots of fourangular crotalaria, dark brown parts of liquorice roots and Chinese magnoliavine fruits, active ingredients with unobstruction force as follows: earthworm, ground beetles, cockroaches, cloves, wrinkled gianthyssop herb, lemongrass herb, artificial musk and ginseng, and active ingredients with expansionary force as follows: ginkgo leaves, ginkgo seeds and roots of maire sophora in parts by weight. The traditional Chinese medicine composition is prepared according to the pathogenesis of diabetes under the medication guiding concept of improvement of transformability of the pancreas, solution of closing force and improvement of penetrating force, plant medicines with dissolution force, expansionary force and unobstruction force are synergistic and matched in use, the curative effect is remarkable and lasts long, the traditional Chinese medicine composition is targeted at focuses, the effective medicine ingredients can be sufficient absorbed and transformed by human tissue, and suffering of a patient is eliminated.
Description
(1) technical field
The present invention relates to a kind of insulin secretion accelerating for diabetes and fall hypoglycemic Chinese medicine composition.
(2) background technology
At present, generally be familiar with according to medical circle, not yet there is the way of radical cure diabetes, generally by adopting multiple treatment means to control this development that is sick and syndrome, as the method etc. that periodic detection blood glucose, employing Diet Therapy and Drug therapy combine in therapeutic process.Wherein, generally adopt insulinize to the treatment of type Ⅰ diabetes mellitus, the maximum untoward reaction of the method easily causes hypoglycemic effect; The medicine adopted the treatment of type Ⅱdiabetes mellitus is more, generally have sulfonylurea drugs and biguanides and α glucosidase inhibitor, meglitinide Insulin secretagogues etc., but said medicine taboo require many (as hepatopathy, nephrotic avoid use, contraindication in pregnancy, fat person avoid use etc.), side effect and untoward reaction excessive.
The present invention is based on the understanding to pathogenesis of diabetes mellitus, think that the basic pathology mechanism of diabetes is pancreatic tissues and dissolves power disappearance and to the closure stress done by glycolytic cycle due to it; This reaction allows pancreatic body presents disorderly phenomenon and secondary dissolves power deficiency, and further causes the enhancing of closing force.
This basic understandings also can be given counterevidence from many complication of diabetes, as the hypertension in complication, hyperglycemia, dyslipidemia, arteriosclerosis, ocular complications, foot symptom the blood vessel that reflects and nervous tissue's mechanical pressure cross high symptom and all further demonstrate the problem that the course of disease of diabetes and the conversion power disappearance of Pathophysiology evolution process and closing force strengthen.The above-mentioned power of dissolving, conversion power, closing force etc., be have interactive Biological Strength in organism, the imbalance of this series of biologic power will cause the stress of organism, i.e. our said disease.
We know, there is respective Biological Strength between biology, as there is expansionary force in Flos Chrysanthemi and Folium Ginkgo, there is dissipation power etc. in Herba Taraxaci and Rhizoma Acori Graminei, and these power in plant correspond to the cardiovascular and cerebrovascular vessel of people and inflammation and other solidification phenomenons respectively.Unidirectional interaction can be produced because power has homogeny.The power of human body disappearance can be provided by the specific power of plant, with the balance making the body of people obtain body force.The mechanics pharmaceutical point derived from by the mutual mechanics of biology, all endogenic disease states, all caused by the enhancing of the power of certain human body or disappearance, to the treatment of disease, fill certain power of its all stress disappearance to exactly this body, meet the action principle of medicine, because the principle of medicine from the angle of mechanics be between biology physical energy and chemical energy interactional, it is the result of people and other biotic interactions, human body is by the bio-energy of various different directions, carry out supplementing the balance completing body health alternately to the bio-energy lacked in human organism in the body of people.
Due to above-mentioned, there is the various medicinal plants of the corresponding occurring in nature of interactive Biological Strength, therefore, can by the phenetic analysis to various disease, determine the various Biological Strengths that body lacks, medicinal plants corresponding to the Biological Strength of this kind of disappearance is selected the treatment being used for organism disease, the medicinal plants with identical effect is worked in coordination with play a role, thus better treat disease.
In Chinese medicine voluminous dictionary, describe 4733 kinds can be used as medicinal plant, and along the plant classification method that " Species Plantarum " how to publish in 1753 according to Sweden botanist woods proposes, detailed classification has been carried out to plant, in these plants, much belong to not equal genus but the plant with same modality may be defined as same pedigree plant.Such as parthenocissus belongs to Vitaceae in Chinese medicine voluminous dictionary, and [function cures mainly] is dispelling wind and removing obstruction in the collateral, promoting blood circulation and detoxication, for rheumatic arthritis; And samphire as Radix Angelicae Pubescentis, Radix Angelicae Sinensis, Rhizoma Chuanxiong and Araliaceae as slender acanthopanax, Rhizoma Panacis Japonici, Caulis Hederae Sinensis etc. all there is the wind alive that dispels the wind, the medicinal function of wet dissipation numbness of dispelling, and they have similar form, belong to same pedigree plant; For another example the plant of not equal genus in diarrhea, as Cob Maydis in Chinese medicine voluminous dictionary, belong to grass family, sunflower plate belongs to Compositae, Pericarpium Granati belongs to Punicaceae, because they have the same modality defended tenaciously and pull, they also have the function of antidiarrheal, belong to same pedigree plant.So the different plants with same modality and function can be defined as same pedigree plant here.
Use same pedigree plant can improve medicine and integration of edible and medicinal herbs food fit function specificity and the high efficiency of plant, medicine and integration of edible and medicinal herbs food is made to have specific and unidirectional power, as utilized the peculiar strength of specified plant (i.e. same modality plant), as aromatics plant the penetration power that has, extension that Umbelliferae and feverfew have etc.Make same pedigree plant carry out reciprocal action by power specific to it and biology, form the corresponding relation of the Biological Strength between biology, by certain human body effectively and certain oneself physical enhancing or disappearance carry out the adjustment of body health.
(3) summary of the invention
The present invention is in order to make up the deficiencies in the prior art, according to the pathogenesis of diabetes, to improve the conversion power of pancreas, solving closing force and strengthening penetration power is medication guide thought, tissue has dissolves power, the medicinal plants of expansion force and unobstructed power, provide a kind of insulin secretion accelerating and reduce blood glucose, evident in efficacy, lastingly, through focus, medicine energy and drug effect can fully be absorbed by tissue and transform, eliminate the Chinese medicine composition of the treatment diabetes of sufferer misery, provide the preparation method of this Chinese medicine composition simultaneously, solve problems of the prior art.
The present invention is achieved through the following technical solutions:
For diabetes insulin secretion accelerating and a hypoglycemic Chinese medicine composition falls, its active component is made up of the raw material of following parts by weight:
Concha Ostreae 10-20 part, Devil Frown 10-20 part, Cortex Ampelopsis Aconitifoliae Radicis 10-20 part, Herba sei Radix Crotalariae tetragonae 10-20 part, Radix Glycyrrhizae uralensis 10-20 part, Fructus Schisandrae Chinensis 10-20 part; Pheretima 10-20 part, eupolyphaga 10-20 part, cockroach 10-20 part, Flos Caryophylli 10-20 part, hair Herba Pogostemonis 10-20 part, Herba Cymbopogonis Citrari 10-20 part, artificial Moschus 10-20 part, Radix Ginseng 10-20 part; Folium Ginkgo 4-12 part, Semen Ginkgo 4-12 part, Radix Sophorae Mairei 4-12 part.
The weight proportion of its preferred each active component is:
Concha Ostreae 15 parts, Devil Frown 15 parts, Cortex Ampelopsis Aconitifoliae Radicis 15 parts, Herba sei Radix Crotalariae tetragonae 15 parts, Radix Glycyrrhizae uralensis 15 parts, Fructus Schisandrae Chinensis 15 parts; Pheretima 15 parts, eupolyphaga 15 parts, cockroach 15 parts, Flos Caryophylli 15 part, mao Herba Pogostemonis 15 parts, 15 parts, Herba Cymbopogonis Citrari, artificial Moschus 15 parts, Radix Ginseng 15 parts; Folium Ginkgo 8 parts, Semen Ginkgo 8 parts, Radix Sophorae Mairei 8 parts.
In above medicament composing prescription, comprise the multiple mechanics medicine being used for the treatment of prostatic disorder, wherein: Concha Ostreae, Devil Frown, Cortex Ampelopsis Aconitifoliae Radicis, Herba sei Radix Crotalariae tetragonae, Radix Glycyrrhizae uralensis, Fructus Schisandrae Chinensis are for dissolving power: Pheretima, eupolyphaga, cockroach, Flos Caryophylli, hair Herba Pogostemonis, Herba Cymbopogonis Citrari, artificial Moschus, Radix Ginseng are unobstructed power; Folium Ginkgo, Semen Ginkgo, Radix Sophorae Mairei are expansionary force.
This is used for the insulin secretion accelerating of diabetes and falls the preparation method of hypoglycemic Chinese medicine composition, comprises following operating procedure:
(1) raw material of above-mentioned parts by weight is got;
(2) detect by infrasonic wave detector the infrasonic wave frequency range that each raw material is intrinsic, the minima of the infrasonic wave frequency range of selected all raw materials and maximum, then get intermediate value;
(3) intermediate value of step (2) is inputted the control device of biological transducer mount (patent No. 201520622992.1), by control device enabling signal generator, make signal generator after power amplifier and speaker, the infrasonic wave that frequency equals the intermediate value of step (2) can be sent;
(4) each raw material in step (1) is put into the pallet of biological transducer mount, enabling signal generator, regularly raw material is taken out and detected by infrasonic wave detector, until the minima of the infrasonic wave frequency range of plant material and maximum reach in set point;
(5) each raw material processed through step (4) is taken out from biological transducer mount, for subsequent use;
(6) by each raw material of step (5) routinely preparation method make ointment plaster, decoction or pill, to obtain final product.
Usage and dosage: the every note metering of plaster that medicament composing prescription of the present invention is made is 20g, is affixed on umbilicus, pastes every day one; The every agent 200mL of decoction that medicament composing prescription of the present invention is made, ante cibum drinks, early, late each potion; Pill every the 5g that medicament composing prescription of the present invention is made, ante cibum eats, each 1 sooner or later.
The pharmaceutical characteristic of each active component that medicament composing prescription of the present invention adopts is as follows:
Concha Ostreae: nature and flavor:.Return liver, kidney channel.Function cures mainly: yin fluid astringing, YANG hyperactivity suppressing, hidroschesis, and arresting seminal emission reduces phlegm, softening the hard mass.Control infantile convulsion, dizzy, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter.
Devil Frown: Fructus Sapindi Mukouossi, nature and flavor: bitter are flat, poisonous.Function cures mainly: heat clearing away, eliminates the phlegm, removing food stagnancy, parasite killing.Control sore throat to swell and ache, cough with asthma, dyspepsia, leucorrhea, infantile malnutrition, skin ulcer numbness, toxic swelling.For diphtheria disease, seminal vesicle is sick, stranguria with turbid discharge frequent micturition.Heat clearing away, eliminates the phlegm, removing food stagnancy, parasite killing.Sore throat swells and ache, cough with asthma, dyspepsia, leucorrhea, infantile malnutrition, skin ulcer tinea, toxic swelling.
Cortex Ampelopsis Aconitifoliae Radicis: nature and flavor: pungent, heat.Function cures mainly: promoting blood circulation to remove blood stasis, eliminating inflammation and expelling toxin, granulation promoting long bone, except wind damp eliminating.Control traumatic injury, fracture, furuncle swells and ache, rheumatic arthritis.
Herba sei Radix Crotalariae tetragonae: nature and flavor: warm in nature, acrid in the mouth is puckery.Function cures mainly: change stagnant, pain relieving.
Radix Glycyrrhizae uralensis: nature and flavor: sweet; Property; Raw cool; Process temperature.Enter the heart; Liver Channel.Function cures mainly: control skin sore, laryngopharynx swelling and pain.
Fructus Schisandrae Chinensis: nature and flavor are sour, sweet, temperature.Return lung, the heart, kidney channel.Function cures mainly: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Pheretima: Lumbricus, nature and flavor are salty, cold.Enter liver, spleen, lung meridian.Function cures mainly: heat clearing away, suppressing the hyperactive liver, Zhichuan, dredging collateral.Control high fanatical hot-tempered, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, apoplexy and hemiplegia, pants, sore throat, arthralgia, bleeding from the gum, urinary obstruction, scrofula.Mumps, skin infection.
Eupolyphaga: have another name called Eupolyphaga Seu Steleophaga, eupolyphaga, salty in the mouth, cold, poisonous, return Liver Channel.There are removing blood stasis, reunion of fractured tendons and bones effect.Clinical in diseases such as amenorrhea, postpartum stagnation, note of the ancient Chinese abdominal masss; Also for fracture and injury, the diseases such as the stagnant pain of the stasis of blood and lumbar strain are bone injury key medicines
Cockroach: Blatta seu periplaneta, nature and flavor: salty, cold.Function cures mainly: removing blood stasis with potent drugs, eliminate indigestion, detumescence, removing toxic substances.Control lump in the abdomen, infantile malnutrition, furuncle, throat moth, carbuncle, snake bite and insect sting.
Flos Caryophylli: nature and flavor are pungent, temperature.Enter stomach, spleen, kidney channel.Function cures mainly: warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI.Control singultus, vomiting, regurgitation, dysentery, trusted subordinate's cold type of pain, mass beside the umbilicus, hernia, tinea disease.
Hair Herba Pogostemonis: nature and flavor: pungent, temperature.Function cures mainly: wind-damp dispelling, detumescence poison, circulation of qi promoting eliminating stasis to stop pain.Dispelling the wind and dampness pathogens osteodynia, abdominal pain due to stagnation of QI, furuncle toxic swelling, skin eczema, pruritus, traumatic injury
Herba Cymbopogonis Citrari: nature and flavor: pungent, temperature.Function cures mainly: dispelling wind to relieve the exterior syndrome, eliminating blood stasis and smoothing collaterals.Cure cold headache, and stomachache, has loose bowels, rheumatic arthralgia, traumatic injury.
Artificial Moschus: the effects such as causing resuscitation with aromatic drugs, the meridian dredging, reducing swelling and alleviating pain, energy coronary artery dilator, Antianginal effect.
Radix Ginseng: nature and flavor: sweet micro-hardship, temperature.Enter spleen, lung meridian.Function cures mainly: strongly invigorating primordial QI, promotes the production of body fluid, calm the nerves Gu de-.Control impairment caused by overstrain deficient, lack of appetite, asthenia, food is told in regurgitation, stool lingering diarrhea, and empty cough with asthma is urged, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, and frequent micturition, quenches one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion, and prolonged deficiency is not multiple, the card of all qi-blood-body fluid deficiencies.
Folium Ginkgo: Folium Ginkgo, nature and flavor: bitter; Sweet; Puckery; Property is put down; Mild toxicity.GUIXIN; Lung; Spleen channel.Function cures mainly: invigorate blood circulation and nourish heart, astringing intestine to stop diarrhea of astringing the lung.Main obstruction of qi in the chest and cardialgia; To breath with cough phlegmatic cough; Dysentery.
Semen Ginkgo: nature and flavor: sweet, bitter, puckery, flat; Poisonous.Return lung meridian.Function cures mainly: astringing lung QI for relieving asthma, and leukorrhagia stopping is turbid, urine reducing.Breath with cough for abundant expectoration, leukorrhagia nebulousurine, enuresis frequent micturition.
Radix Sophorae Mairei: cool in nature, bitter and puckery flavor.Function cures mainly: removing damp-heat.Control consumptive disease wound, watery diarrhea.
Beneficial effect of the present invention: generally all contain several even tens kinds of ingredients in existing Chinese Traditional Medicines, that wherein really plays drug effect to disease only has one or two kind, other composition changes in order to side effect, its shortcoming of this dosage mainly contains: the property of medicine is low, weak curative effect, specificity is poor, and side effect is large, add medicine category, add drug cost.The present invention for diabetes insulin secretion accelerating and to fall hypoglycemic Chinese medicine composition be basis at traditional medicine and modern medicine, in conjunction with the mechanics medicine concept that inventor is derived from through the mutual mechanics of biology of hammer away for many years, think, the root of diabetes because pancreatic body closed result in the decomposition of sugar and the deficiency of conversion, so use expansionary force and current power to make pancreatic body recover normal and strengthen it to dissolve power be basic, therefore, supplement the medicinal plants with above-mentioned several disappearance power with the use of, can first in a short time the complication symptom of diabetes-alleviating the source of disease body of this disease of solution step by step and pancreatic body dissolve power, transform hypodynamic root.Adopt Concha Ostreae, Devil Frown, Cortex Ampelopsis Aconitifoliae Radicis, Herba sei Radix Crotalariae tetragonae, Radix Glycyrrhizae uralensis, Fructus Schisandrae Chinensis is main dissolve power, Pheretima, eupolyphaga, cockroach, Flos Caryophylli, hair Herba Pogostemonis, Herba Cymbopogonis Citrari, artificial Moschus, Radix Ginseng is main unobstructed power and Folium Ginkgo, Semen Ginkgo, Radix Sophorae Mairei is that main expansionary force combinationally uses, and has the Concha Ostreae of dissolving power, Devil Frown, mutually work in coordination with between the medicinal plants such as Cortex Ampelopsis Aconitifoliae Radicis, make up pancreatic body present disorderly phenomenon and secondary dissolve power deficiency, there is the Folium Ginkgo of expansionary force, Semen Ginkgo and Radix Sophorae Mairei interact, and body and the external world are formed a kind of alternately open, and supplement the Pheretima with unobstructed power further, the medicinal plants such as eupolyphaga, thus realize supplementing and strengthening of the above-mentioned disappearance power of diabetics, overall solution pancreatic tissue dissolves the problem of the closure stress done by power disappearance, calm down pancreas disorders phenomenon gradually, pancreatic function is made to recover normal, overcome pancreas because of closing force cannot normal secretions insulin or oozy insulin not for decompose glycogen problem, strengthen unobstructed power, fundamentally solve this disease crux.This is used for the insulin secretion accelerating of diabetes and to fall hypoglycemic Chinese medicine composition lastingly evident in efficacy, prove effective rapidly, safe and reliable, effectively can treat the complication such as diabetes and hypertension, hyperglycemia, dyslipidemia, arteriosclerosis, ocular complications, foot symptom, regulate body to strengthen immunity.
Adopt above-mentioned biological transducer mount, by the infrasonic wave frequency range that the medicinal plants detecting above-mentioned raw materials is intrinsic, then intermediate value is got, send by Subsonic wave generator the infrasonic wave being equal to intermediate value again and act on medicinal plants, molecule in medicinal plants is polymerized near the frequency of setting, strengthen intermolecular interaction, collaborative intermolecular same function and stability, the effect of effective ingredient in fortification of plants medicine, reduce the side effect of medicinal plants, real tool medicative several plant medicine only need be taken when making up a prescription, without the need to admixture, other suppresses the medicinal plants of side effect, decrease ingredient kind, reduce pharmacy cost, the property of medicine is high, good effect, specificity is good, side effect is little.
Application the present invention is used for the insulin secretion accelerating of diabetes and falls the medicine ointment plaster of hypoglycemic Chinese medicine composition, and treat 326 routine diabeticss altogether, total effective rate reaches 96%; Application the present invention is used for the insulin secretion accelerating of diabetes and falls the medicine decoction of hypoglycemic Chinese medicine composition, and treat 302 routine diabeticss altogether, total effective rate reaches 96.3%; Application the present invention is used for the insulin secretion accelerating of diabetes and falls the bolus of drug of hypoglycemic Chinese medicine composition, and treat 298 routine diabeticss altogether, total effective rate reaches 95.9%.
(4) detailed description of the invention
Below in conjunction with embodiment, the invention will be further described, but the present invention is not limited thereto, and the preparation method of the plaster in embodiment, decoction and pill is customary preparation methods, no longer describes in detail.
Embodiment 1:
This is used for the insulin secretion accelerating of diabetes and falls hypoglycemic Chinese medicine composition, and its active component is made up of the raw material of following weight:
Concha Ostreae 15g, Devil Frown 15g, Cortex Ampelopsis Aconitifoliae Radicis 15g, Herba sei Radix Crotalariae tetragonae 15g, Radix Glycyrrhizae uralensis 15g, Fructus Schisandrae Chinensis 15g; Pheretima 15g, eupolyphaga 15g, cockroach 15g, Flos Caryophylli 15g, hair Herba Pogostemonis 15g, Herba Cymbopogonis Citrari 15g, artificial Moschus 15g, Radix Ginseng 15g; Folium Ginkgo 8g, Semen Ginkgo 8g, Radix Sophorae Mairei 8g.
This is used for the insulin secretion accelerating of diabetes and falls the preparation method of hypoglycemic Chinese medicine composition, adopts following steps:
(1) raw material of above-mentioned weight is got;
(2) detect by infrasonic wave detector the infrasonic wave frequency range that each raw material is intrinsic, the minima of the infrasonic wave frequency range of selected all raw materials and maximum, then get intermediate value;
(3) intermediate value of step (2) is inputted the control device of biological transducer mount (patent No. 201520622992.1), by control device enabling signal generator, make signal generator after power amplifier and speaker, the infrasonic wave that frequency equals the intermediate value of step (2) can be sent;
(4) each raw material in step (1) is put into the pallet of biological transducer mount, enabling signal generator, regularly raw material is taken out and detected by infrasonic wave detector, until the minima of the infrasonic wave frequency range of plant and maximum reach in set point;
(5) each raw material processed through step (4) is taken out from biological transducer mount, for subsequent use;
(6) each raw material of step (5) is made ointment plaster by the preparation method of Chinese medicine external plaster, to obtain final product.
Usage and dosage: the every note metering of plaster that medicament composing prescription of the present invention is made is 20 grams, and be affixed on umbilicus, every day one pastes.
Embodiment 2:
This is used for the insulin secretion accelerating of diabetes and falls hypoglycemic Chinese medicine composition, and its active component is made up of the raw material of following weight:
Concha Ostreae 10g, Devil Frown 10g, Cortex Ampelopsis Aconitifoliae Radicis 10g, Herba sei Radix Crotalariae tetragonae 10g, Radix Glycyrrhizae uralensis 10g, Fructus Schisandrae Chinensis 10g; Pheretima 10g, eupolyphaga 10g, cockroach 10g, Flos Caryophylli 10g, hair Herba Pogostemonis 10g, Herba Cymbopogonis Citrari 10g, artificial Moschus 10g, Radix Ginseng 10g; Folium Ginkgo 4g, Semen Ginkgo 4g, Radix Sophorae Mairei 4g.
This is used for the insulin secretion accelerating of diabetes and falls the preparation method of hypoglycemic Chinese medicine composition, adopts following steps:
(1) raw material of above-mentioned weight is got;
(2) detect by infrasonic wave detector the infrasonic wave frequency range that each raw material is intrinsic, the minima of the infrasonic wave frequency range of selected all raw materials and maximum, then get intermediate value;
(3) intermediate value of step (2) is inputted the control device of biological transducer mount (patent No. 201520622992.1), by control device enabling signal generator, make signal generator after power amplifier and speaker, the infrasonic wave that frequency equals the intermediate value of step (2) can be sent;
(4) each raw material in step (1) is put into the pallet of biological transducer mount, enabling signal generator, regularly raw material is taken out and detected by infrasonic wave detector, until the minima of the infrasonic wave frequency range of plant and maximum reach in set point;
(5) each raw material processed through step (4) is taken out from biological transducer mount, for subsequent use;
(6) each raw material of step (5) is made decoction by the preparation method of Chinese medicine decoction, to obtain final product.
Usage and dosage: the every agent 200mL of decoction that medicament composing prescription of the present invention is made, ante cibum quotes, early, late each potion.
Embodiment 3:
This is used for the insulin secretion accelerating of diabetes and falls hypoglycemic Chinese medicine composition, and its active component is made up of the raw material of following weight:
Concha Ostreae 20g, Devil Frown 20g, Cortex Ampelopsis Aconitifoliae Radicis 20g, Herba sei Radix Crotalariae tetragonae 20g, Radix Glycyrrhizae uralensis 20g, Fructus Schisandrae Chinensis 20g; Pheretima 20g, eupolyphaga 20g, cockroach 20g, Flos Caryophylli 20g, hair Herba Pogostemonis 20g, Herba Cymbopogonis Citrari 20g, artificial Moschus 20g, Radix Ginseng 20g; Folium Ginkgo 12g, Semen Ginkgo 12g, Radix Sophorae Mairei 12g.
This is used for the insulin secretion accelerating of diabetes and falls the preparation method of hypoglycemic Chinese medicine composition, adopts following steps:
(1) raw material of above-mentioned weight is got;
(2) detect by infrasonic wave detector the infrasonic wave frequency range that each raw material is intrinsic, the minima of the infrasonic wave frequency range of selected all raw materials and maximum, then get intermediate value;
(3) intermediate value of step (2) is inputted the control device of biological transducer mount (patent No. 201520622992.1), by control device enabling signal generator, make signal generator after power amplifier and speaker, the infrasonic wave that frequency equals the intermediate value of step (2) can be sent;
(4) each raw material in step (1) is put into the pallet of biological transducer mount, enabling signal generator, regularly raw material is taken out and detected by infrasonic wave detector, until the minima of the infrasonic wave frequency range of plant and maximum reach in set point;
(5) each raw material processed through step (4) is taken out from biological transducer mount, for subsequent use;
(6) each raw material of step (5) is made pill by the preparation method of medicine pill, to obtain final product.
Usage and dosage: pill every the 5g that medicament composing prescription of the present invention is made, ante cibum eats, each 1 sooner or later.
Embodiment 4:
This is used for the insulin secretion accelerating of diabetes and falls hypoglycemic Chinese medicine composition, and its active component is made up of the raw material of following weight:
Concha Ostreae 12g, Devil Frown 11g, Cortex Ampelopsis Aconitifoliae Radicis 12g, Herba sei Radix Crotalariae tetragonae 12g, Radix Glycyrrhizae uralensis 12g, Fructus Schisandrae Chinensis 12g; Pheretima 13g, eupolyphaga 13g, cockroach 12g, Flos Caryophylli 12g, hair Herba Pogostemonis 12g, Herba Cymbopogonis Citrari 12g, artificial Moschus 12g, Radix Ginseng 12g; Folium Ginkgo 6g, Semen Ginkgo 6g, Radix Sophorae Mairei 6g.
Preparation method and usage and dosage are with embodiment 1.
Embodiment 5:
This is used for the insulin secretion accelerating of diabetes and falls hypoglycemic Chinese medicine composition, and its active component is made up of the raw material of following weight:
Concha Ostreae 17g, Devil Frown 16g, Cortex Ampelopsis Aconitifoliae Radicis 18g, Herba sei Radix Crotalariae tetragonae 17g, Radix Glycyrrhizae uralensis 17g, Fructus Schisandrae Chinensis 18g; Pheretima 18g, eupolyphaga 18g, cockroach 17g, Flos Caryophylli 17g, hair Herba Pogostemonis 18g, Herba Cymbopogonis Citrari 17g, artificial Moschus 18g, Radix Ginseng 18g; Folium Ginkgo 10g, Semen Ginkgo 10g, Radix Sophorae Mairei 10g.
Preparation method and usage and dosage are with embodiment 2.
Embodiment 6
This is used for the insulin secretion accelerating of diabetes and falls hypoglycemic Chinese medicine composition, and its active component is made up of the raw material of following weight:
Concha Ostreae 17g, Devil Frown 12g, Cortex Ampelopsis Aconitifoliae Radicis 14g, Herba sei Radix Crotalariae tetragonae 15g, Radix Glycyrrhizae uralensis 15g, Fructus Schisandrae Chinensis 18g; Pheretima 18g, eupolyphaga 18g, cockroach 17g, Flos Caryophylli 17g, hair Herba Pogostemonis 14g, Herba Cymbopogonis Citrari 15g, artificial Moschus 16g, Radix Ginseng 15g; Folium Ginkgo 8g, Semen Ginkgo 10g, Radix Sophorae Mairei 6g.
Preparation method and usage and dosage are with embodiment 3.
Clinical observation on the therapeutic effect:
1, clinical data
Adopt the present invention be used for the insulin secretion accelerating of diabetes and fall the ointment plaster of hypoglycemic Chinese medicine composition, carry out clinical verification to clinical 326 routine diabeticss, cure 196 examples, effective 117 examples, invalid 13 examples, total effective rate reaches 96%;
Adopt the present invention be used for the insulin secretion accelerating of diabetes and fall the decoction of hypoglycemic Chinese medicine composition, carry out clinical verification to clinical 302 routine diabeticss, cure 190 examples, effective 101 examples, invalid 11 examples, total effective rate reaches 96.3%;
Adopt the present invention be used for the insulin secretion accelerating of diabetes and fall the pill of hypoglycemic Chinese medicine composition, carry out clinical verification to clinical 298 routine diabeticss, cure 192 examples, effective 94 examples, invalid 12 examples, total effective rate reaches 95.9%.
2, diagnostic method
Clinical symptoms: polydipsia polyphagia, thirsty polyphagia, polyuria is become thin; Night sweat, cardiopalmus, breathes hard, weak, constipation; Red tongue, corpulent tongue is large.Blood glucose is higher than 11.1mmol/L.When looking into fasting glucose, more than twice all higher than 7.8mmol/L.
3, Therapeutic Method
Use the present invention for the insulin secretion accelerating of diabetes and the ointment plaster falling hypoglycemic Chinese medicine composition, every note metering is 20g, and being affixed on umbilicus, pasting every day one, 1 month is a course for the treatment of, treats 3 courses for the treatment of continuously; Stadium is treated with 4-6 month as observation caliber;
Use the present invention be used for the insulin secretion accelerating of diabetes and fall the decoction of hypoglycemic Chinese medicine composition, every agent 200mL, ante cibum drinks, and early, late each potion, within 1 month, is a course for the treatment of, continuously 3 courses for the treatment of of treatment; Stadium is treated with 4-6 month as observation caliber;
Use the present invention be used for the insulin secretion accelerating of diabetes and fall the pill of hypoglycemic Chinese medicine composition, every 5g, ante cibum eats, and early, each 1 of evening, within 1 month, is a course for the treatment of, continuously 3 courses for the treatment of of treatment; Stadium is treated with 4-6 month as observation caliber.
4, therapeutic effect judges
A, healing: blood glucose and glucose in urine control in normal value; Eliminate or greatly reduce night sweat, cardiopalmus, breathing hard, weak, constipation and other clinical symptoms before taking this medicine;
B, effectively: blood glucose and urine sugar value control, in certain limit, no longer to raise;
C, invalid: Clinical symptom and sign, without improvement, even increases the weight of.
5, therapeutic outcome
Adopt 326 routine clinical diabetes patients of the insulin secretion accelerating being used for diabetes and the ointment plaster falling hypoglycemic Chinese medicine composition treatment, cure 196 examples, effective 117 examples, invalid 13 examples, total effective rate reaches 96%;
Adopt 302 routine clinical diabetes patients of the insulin secretion accelerating being used for diabetes and the decoction falling hypoglycemic Chinese medicine composition treatment, cure 190 examples, effective 101 examples, invalid 11 examples, total effective rate reaches 96.3%;
Adopt 298 routine clinical diabetes patients of the insulin secretion accelerating being used for diabetes and the pill falling hypoglycemic Chinese medicine composition treatment, cure 192 examples, effective 94 examples, invalid 12 examples, total effective rate reaches 95.9%.
Model case:
Case 1: Bao, man, 49 years old, teacher, suffered from diabetes 5 years, and simultaneously with hypertension, blood fat is high, hypertension, dizziness, headache, numb limbs and tense tendons, uncomfortable in chest unable.After the made ointment plaster of the docile embodiment of the present invention 1 treats 4 months, blood fat recovers normal, and blood glucose starts to stablize, and above-mentioned symptom disappears substantially, checks after half a year, and 2h-plasma glucose is stabilized in 7.5mmol/L, has no recurrence.
Case 2: blue certain, man, 60 years old, peasant, suffered from diabetes 10 years, was interrupted before and took Western medicine, blood glucose after disconnected medicine through often rising to more than 12mmol/L; Once direct injection insulin administration is adopted, effective, but painful large, and leave insulin and change that to take after oral medicine blood glucose in 1 month still high.After change and take after the made decoction of the embodiment of the present invention 2 treats 3 first quarter moons, blood glucose till was stabilized in normal range.Check after 5 months, 2h-plasma glucose is stabilized in 7.5mmol/L, has no recurrence.
Case 3: Zhang, man, 62 years old, peasant, suffered from diabetes 8 years.Fat, often thirsty, unable, suffer from diabetes through looking into, thick blood fat, frequent constipation, take after the made ointment plaster of the embodiment of the present invention 4 treats 5 months, above-mentioned symptom disappears, and through looking into, blood glucose, glucose in urine are stable, and blood fat chemical examination is normal.
Case 4: Lin, female, 55 years old, private owner.Suffer from diabetes, hyperlipidemia, coronary heart disease, fat, slightly movable just tired, total feel face is felt nervous, hands swells, and takes after the made pill of the embodiment of the present invention 3 treats 3 months, stablizes through sugar of having a blood test, glucose in urine, blood fat chemical examination is normal, and feel nervous symptom of swelling of face is able to good improvement.
Case 5: Deng, female, 65 years old, editor.Suffer from diabetes 6 years, frequent myasthenia of limbs, cardiopalmus is uncomfortable in chest, out of spirits, easily irritated, once adopted injection of insulin treatment, take western medicine after blood glucose is normal, but occur that extremity are swelled, breathe hard, eyes Fuzzy symptom, drug withdrawal is afterwards after 1 year, take the made decoction treatment of the embodiment of the present invention 5, after 4 first quarter moons, numb limbs and tense tendons and swelling transference cure, blood sugar urinary sugar recovers normal, and symptom is clearly better.
Case 6: Cai, man, 50 years old, cook.Suffer from diabetes 5 years, frequent cardiopalmus is uncomfortable in chest, weak, there is no spirit, easily irritated, through looking into also with thick blood fat, heart disease, prolonged constipation, once adopted injection of insulin treatment, take western medicine after blood glucose is normal, side effect is large, change and take after the made pill of the embodiment of the present invention 6 treats 5 months, above-mentioned symptom disappears substantially, and blood sugar urinary sugar recovers normal, and symptom is clearly better.
Claims (3)
1. for diabetes insulin secretion accelerating and a hypoglycemic Chinese medicine composition falls, it is characterized in that: its active component is made up of the raw material of following parts by weight:
Concha Ostreae 10-20 part, Devil Frown 10-20 part, Cortex Ampelopsis Aconitifoliae Radicis 10-20 part, Herba sei Radix Crotalariae tetragonae 10-20 part, Radix Glycyrrhizae uralensis 10-20 part, Fructus Schisandrae Chinensis 10-20 part; Pheretima 10-20 part, eupolyphaga 10-20 part, cockroach 10-20 part, Flos Caryophylli 10-20 part, hair Herba Pogostemonis 10-20 part, Herba Cymbopogonis Citrari 10-20 part, artificial Moschus 10-20 part, Radix Ginseng 10-20 part; Folium Ginkgo 4-12 part, Semen Ginkgo 4-12 part, Radix Sophorae Mairei 4-12 part.
2. the insulin secretion accelerating for diabetes according to claim 1 and fall hypoglycemic Chinese medicine composition, is characterized in that: its active component is made up of the raw material of following parts by weight:
Concha Ostreae 15 parts, Devil Frown 15 parts, Cortex Ampelopsis Aconitifoliae Radicis 15 parts, Herba sei Radix Crotalariae tetragonae 15 parts, Radix Glycyrrhizae uralensis 15 parts, Fructus Schisandrae Chinensis 15 parts; Pheretima 15 parts, eupolyphaga 15 parts, cockroach 15 parts, Flos Caryophylli 15 part, mao Herba Pogostemonis 15 parts, 15 parts, Herba Cymbopogonis Citrari, artificial Moschus 15 parts, Radix Ginseng 15 parts; Folium Ginkgo 8 parts, Semen Ginkgo 8 parts, Radix Sophorae Mairei 8 parts.
3. prepare as claimed in claim 1 for insulin secretion accelerating and the method for falling hypoglycemic Chinese medicine composition of diabetes, it is characterized in that: comprise following operating procedure:
(1) raw material of above-mentioned parts by weight is got;
(2) detect by infrasonic wave detector the infrasonic wave frequency range that each raw material is intrinsic, the minima of the infrasonic wave frequency range of selected all raw materials and maximum, then get intermediate value;
(3) intermediate value of step (2) is inputted the control device of biological transducer mount, by control device enabling signal generator, make signal generator after power amplifier and speaker, the infrasonic wave that frequency equals the intermediate value of step (2) can be sent;
(4) each raw material in step (1) is put into the pallet of biological transducer mount, enabling signal generator, regularly each raw material is taken out and detected by infrasonic wave detector, until the minima of the infrasonic wave frequency range of raw material and maximum reach in set point;
(5) each raw material processed through step (4) is taken out from biological transducer mount, for subsequent use;
(6) each raw material of step (5) is made ointment plaster, decoction or pill, to obtain final product.
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| CN101940198A (en) * | 2009-07-05 | 2011-01-12 | 李方涵 | Infrasonic resonance deinsectization technique |
| CN103205354A (en) * | 2013-03-28 | 2013-07-17 | 王勇 | Infrasonic wave loading wine aging method and apparatus for implementing the method |
| CN104435535A (en) * | 2014-11-11 | 2015-03-25 | 郑玉柱 | Health medicament for treating type 2 diabetes mellitus |
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- 2015-10-28 CN CN201510717984.XA patent/CN105194412A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101840008A (en) * | 2009-03-18 | 2010-09-22 | 中国石油天然气集团公司 | Multifunctional seismic hydrophone tester |
| CN101940198A (en) * | 2009-07-05 | 2011-01-12 | 李方涵 | Infrasonic resonance deinsectization technique |
| CN103205354A (en) * | 2013-03-28 | 2013-07-17 | 王勇 | Infrasonic wave loading wine aging method and apparatus for implementing the method |
| CN104435535A (en) * | 2014-11-11 | 2015-03-25 | 郑玉柱 | Health medicament for treating type 2 diabetes mellitus |
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Application publication date: 20151230 |