CN105194122A - Traditional Chinese medicine for treating numbness of lower limbs after operation of lumbar intervertebral disc protrusion - Google Patents
Traditional Chinese medicine for treating numbness of lower limbs after operation of lumbar intervertebral disc protrusion Download PDFInfo
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Abstract
The invention belongs to the technical field of medicines, and particularly relates to a traditional Chinese medicine for treating numbness of lower limbs after an operation of the lumbar intervertebral disc protrusion. The traditional Chinese medicine comprises herbal medicines in parts by weight as follows: 4-8 parts of Aralia undulata, 4-8 parts of Davallia formosana Hay., 4-8 parts of Sarcococca hookeriana Baill., 4-8 parts of Platycarya strobilacea Sieb.et Zucc, 4-8 parts of Ficus lacor Buch.-Ham, 4-8 parts of roots of Delavay Ampelopsis, 4-8 parts of roots of Centranthera grandiflora Benth., 4-8 parts of Pachysandra axillaris Franch., 4-8 parts of roots of Tylophora yannanensis Schlecht. and 4-8 parts of liquorice. The medicines are used together and perform efficacy of promotion of qi circulation and blood circulation and stasis removal, is targeted at the etiology and pathogenesis of numbness of the lower limbs after the operation of the lumbar intervertebral disc protrusion, and can effectively relieve the numbness symptom of a patient.
Description
Technical field
The invention belongs to medical art, be specifically related to a kind of Chinese medicine for the treatment of Lumbar Disc herniation resection numbness of lower limbs.
Background technology
Resection of nucleus pulposus is one of common method for the treatment of prolapse of lumbar intervertebral disc, postoperative patient lumbago and skelalgia symptom is alleviated very soon, but nerve root of getting involved areal area is numb, big toe dorsiflexion and plantar flexion muscular strength weaken and recover slowly, even can not recover, and most of patients remains buttocks legs in the postoperative short time, these clinical manifestations are called the numb syndrome of Lumbar Disc herniation resection, have had a strong impact on work and the life of patient.Have not yet to see the Chinese medicine being exclusively used in treatment Lumbar Disc herniation resection numbness of lower limbs.
Summary of the invention
Technical problem to be solved by this invention avoids the weak point existing for above-mentioned prior art, provides a kind of Chinese medicine for the treatment of Lumbar Disc herniation resection numbness of lower limbs.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine for Lumbar Disc herniation resection numbness of lower limbs, be made up of the Chinese medicine of following weight portion:
Radix Araliae undulatae 4-8 part, great Ye Rhizoma Drynariae 4-8 part, thick leaf tree 4-8 part, Fructus Platycaryae strobilaceac 4-8 part, Galla Fici lacoris 4-8 part, Radix Ampelopsis delavayanae 4-8 part, golden Caput Felis domestica 4-8 part, Pachysandra axillaris Franch. 4-8 part, Radix Tylophorae Yunnanensis 4-8 part, Radix Glycyrrhizae 4-8 part.
Preferably, the Chinese medicine of above-mentioned treatment Lumbar Disc herniation resection numbness of lower limbs, is made up of the Chinese medicine of following weight portion:
Radix Araliae undulatae 5-7 part, great Ye Rhizoma Drynariae 5-7 part, thick leaf tree 5-7 part, Fructus Platycaryae strobilaceac 5-7 part, Galla Fici lacoris 5-7 part, Radix Ampelopsis delavayanae 5-7 part, golden Caput Felis domestica 5-7 part, Pachysandra axillaris Franch. 5-7 part, Radix Tylophorae Yunnanensis 5-7 part, Radix Glycyrrhizae 5-7 part.
Preferred, the Chinese medicine of above-mentioned treatment Lumbar Disc herniation resection numbness of lower limbs, is made up of the Chinese medicine of following weight portion:
Radix Araliae undulatae 6 parts, great Ye Rhizoma Drynariae 6 parts, thick leaf set 6 parts, Fructus Platycaryae strobilaceac 6 parts, Galla Fici lacoris 6 parts, Radix Ampelopsis delavayanae 6 parts, golden Caput Felis domestica 6 parts, Pachysandra axillaris Franch. 6 parts, Radix Tylophorae Yunnanensis 6 parts, 6 parts, Radix Glycyrrhizae.
The ratio of above weight proportion is through that science screening obtains, and for especial patient, as serious symptom or mild, fat or modest patient, can the proportioning of amount of corresponding adjustment composition, and increase or reduce being no more than 100%, drug effect is substantially constant.
The weight portion of said medicine, if in units of g, the normally consumption of 1 dose.
The indication of Chinese medicine of the present invention: be used for the treatment of Lumbar Disc herniation resection numbness of lower limbs.
The taboo item of Chinese medicine of the present invention: the fasting for the treatment of period in a medicine is greasy, raw and cold, the smelling of fish or mutton, irritant and stodgy food.
In Chinese medicine of the present invention,
Radix Araliae undulatae another name HONGCI brain bag, sky, top thorn, Aralia mandshurica, Sedum aizoon L., purplish red umbrella are the root of Araliaceae Radix Araliae undulatae AraliaundulataHand.-Mazz.Bitter in the mouth; Pungent; Cool in nature.Function blood circulation promoting and blood stasis dispelling; Inducing menstruation to relieve menalgia; Expelling wind and removing dampness.Main traumatic injury; Fracture; Mass in the abdomen; Amenorrhea; Dysmenorrhea; Impairment caused by overstrain pain; Rheumatalgia.
Great Ye Rhizoma Drynariae is the rhizome of Davalliaceae plant great Ye Rhizoma Drynariae.Latin plant animal mineral are called: DavalliadivaricataBl. ［ D.formosanaHayata; D.orientalisC.Chr. ］.Nature and flavor are bitter; Temperature.Function blood circulation promoting and blood stasis dispelling; Invigorating the kidney and strengthening the bones; Wind-expelling pain-stopping.Main traumatic injury; Lumbago due to renal deficiency; Rheumatic ostalgia.
Thick leaf tree another name Radix osteomelis schwerinais Sarcococca ruscifolia Stapf, thousand young, century-old green grass or young crops.For open country, Buxaceae plant Yunnan fan flower SarcococcawallichiiStapf ［ S.coriaceaMull.Arg.; S.pruniformisauct.nonLindl. ］ Herb.Acrid in the mouth; Bitter; Property is put down.Function blood-activating and qi-promoting; Reducing swelling and alleviating pain.Main gastralgia; Traumatic injury; Innominate toxic swelling.
The Aliasing XIANGSHU ball of Fructus Platycaryae strobilaceac, change Oleum Linderae are the infructescence of juglandaceae plant Platycarya strobilacea PlatycaryastrobilaceaSieb.etZucc. [P.sinensisMottet] 2.PlatycaryalongipesWu. [P.kwangtungen-sisChun].Acrid in the mouth; Warm in nature.Function blood-activating and qi-promoting; Pain relieving; Killing parasites for relieving itching.Main internal injury breast is swollen; Stomachache; Traumatic injury; Bones and muscles pain; Carbuncle; Eczema; Scabies.
The insect gall that Galla Fici lacoris is formed by parasite for yellow Ge Shu FicusvirensAit.var.sublanceolata (Miq.) Corner [F.lacorsensuauct.nonBuch.-Ham.] root of moraceae plants.Bitter in the mouth; Warm in nature.Function is dispeled the wind except temperature; Promoting blood circulation to remove obstruction in the collateral.Main air temperature arthralgia; Impairment caused by overstrain lumbago.
Radix Ampelopsis delavayanae another name Ramulus et Folium Bischofiae Javanicae is logical, wild Jambul root, five pawl gold, Radix vitis romanetii, Delavay ampelopsis root, Hypoestes poilanei R. Benoistr., Herba Ipomoeae Cairicae, tetrastigma hemsleyanum, red Caulis et Folium cayratiae trifoliae, Radix seu folium Gaultheriae intermediae, fly Caulis Zanthoxyli multijugi, JIANZHONGXIAO, red red Pueraria lobota, red internal diabetes, red Pueraria lobota, black Caulis seu Radix Schisandrae Henryi, SANYE rattan, red Canis familiaris L. poplar.For root or the ratan of vitaceae trilobated leaf Caulis seu folium ampelopsis brevipedunculatae (Caulis Ampelopsis Brevipedunculae) Ampelopsisdelavayana (Franch.) Planch. [VitisdelavayanaFranch.].Acrid in the mouth; Light; Puckery; Property is put down.GUIXIN; Liver Channel.Function clearing away heat-damp and promoting diuresis; Promoting blood circulation to remove obstruction in the collateral; Hemostasia and promoting granulation; Removing toxic substances and promoting subsidence of swelling.Main stranguria; Nebulousurine; Hernia; The swelling and hanging down of either of the testes; Rheumatic arthralgia; Traumatic injury congestive edema; Wound hemorrhage; Scald; Carbuncle sore.
The sliding Bombyx mandarina Moore bean of gold Caput Felis domestica another name, Bombyx mandarina Moore bean, little red medicine, Bleeding-Stopping Bolus, Ganoderma lucidum seu Japonicum, derive from Scrophulariaceae Herba Centrantherae Cochinchinensis platymiscium Centranthera grandiflora Benth CentrantheragrandifloraBenth., be used as medicine with root.Sweet in the mouth, light, warm in nature.Function promoting blood flow to regulate menstruation, relaxing muscles and tendons and activating QI and blood in the collateral, pain relieving.For amenorrhea, dysmenorrhea, metrorrhagia, traumatic injury, rheumatic ostalgia; Traumatic hemorrhage is controlled in external.
Pachysandra axillaris Franch. calls short, Herba Pachysandrae Stylosae in thousand, derives from Buxaceae powder stamen Buxus Plant Powder stamen Buxus sinica (Rehd.et Wils.) PachysandraaxillarisFranch., is used as medicine with Herb.Acrid in the mouth, hardship, warm in nature.Function dispelling wind dehumidifies, relaxing muscles and tendons and activating QI and blood in the collateral.For rheumatic arthritis, numb limbs and tense tendons, traumatic injury.
Radix Tylophorae Yunnanensis another name Radix Tylophorae Yunnanensis, grandma's sewing kit, wild Fructus Capsici, Radix Alangii, water spicy root, Serpentis spicy, Herba Calami tetradactyli, derive from asclepiadaceae Tylophora plant Yunnan Radix tylophorae floribundae TylophorayannanensisSchlecht., be used as medicine with root.Bitter in the mouth, puckery, warm in nature.Function relaxing muscles and tendons and activating QI and blood in the collateral, menstruction regulating and pain relieving, preventing the attack (or recurrence) of malaria.For hepatitis, gastric ulcer, malaria, rheumatic arthritis, traumatic injury; Worm venom is controlled in external.
Radix Glycyrrhizae is sweet, flat.GUIXIN, lung, spleen, stomach warp.Function invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Prolapse of lumbar intervertebral disc person, with the passing of time the common state of an illness touching, and often through expectant treatment remission, but Relapse rate, disease enters network for a long time, and this disease is often obstructed because of the resistance of QI and blood numbness, and muscle arteries and veins joint is lost caused by moisten and support.Operation can extract vertebral pulp, removes compressing, but operation also damages meridians, muscle and tendon injury consumption gas, cause patient's stagnation of blood stasis more very, healthy energy benefit is empty, QI-blood circulation is smooth, phlegm resistance, and notably blood stasis and phlegm-damp are tied mutually to fight and tie, is deteriorated case.Postoperative patient; after operation wound, must there be blood circulating out of vessels local, and blood stasis stops amassing, the twinge of blood choke stagnant event waist; the blood circulating out of vessels stasis of blood to amass between muscle arteries and veins kindred then localized pain; in operation, qi-blood-body fluid consume more injures human righteousness, deficiency of vital QI simultaneously, and venation is damaged; stagnation of blood stasis; QI-blood circulation is smooth, and lower limb moisten supports deficiency, therefore sees apathy.Lumbar Disc herniation resection numbness of lower limbs pathogenesis is main relevant with qi depression to blood stasis, and treatment is worked as with promoting flow of QI and blood blood stasis dispelling.
Chinese medicine of the present invention, its prescription mechanism is as follows:
Monarch drug: Radix Araliae undulatae, great Ye Rhizoma Drynariae merit are with blood circulation promoting and blood stasis dispelling.Ministerial drug: thick leaf tree, Fructus Platycaryae strobilaceac merit are with blood-activating and qi-promoting.Adjuvant drug: Galla Fici lacoris, Radix Ampelopsis delavayanae merit are with promoting blood circulation to remove obstruction in the collateral, and golden Caput Felis domestica, Pachysandra axillaris Franch., Radix Tylophorae Yunnanensis merit are with relaxing muscles and tendons and activating QI and blood in the collateral.Make medicine: Radix Glycyrrhizae merit is with coordinating the actions of various ingredients in a prescription.We's compatibility is reasonable, and all medicines share plays promoting flow of QI and blood blood stasis dispelling, the effect of channels sootheing and network vessel quickening altogether, the etiology and pathogenesis of the Lumbar Disc herniation resection numbness of lower limbs that links closely, can effectively alleviate patient's pain and numbness, recover shallow, the deep sensory function of patients' neural, be applicable to the postoperative dialectical patient for qi depression to blood stasis.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Treat a Chinese medicine for Lumbar Disc herniation resection numbness of lower limbs, each crude drug weight proportion is as follows:
Radix Araliae undulatae 6g, great Ye Rhizoma Drynariae 6g, thick leaf tree 6g, Fructus Platycaryae strobilaceac 6g, Galla Fici lacoris 6g, Radix Ampelopsis delavayanae 6g, golden Caput Felis domestica 6g, Pachysandra axillaris Franch. 6g, Radix Tylophorae Yunnanensis 6g, Radix Glycyrrhizae 6g.
Embodiment 2
Treat a Chinese medicine for Lumbar Disc herniation resection numbness of lower limbs, each crude drug weight proportion is as follows:
Radix Araliae undulatae 5g, great Ye Rhizoma Drynariae 5g, thick leaf tree 5g, Fructus Platycaryae strobilaceac 5g, Galla Fici lacoris 5g, Radix Ampelopsis delavayanae 5g, golden Caput Felis domestica 5g, Pachysandra axillaris Franch. 5g, Radix Tylophorae Yunnanensis 5g, Radix Glycyrrhizae 5g.
Embodiment 3
Treat a Chinese medicine for Lumbar Disc herniation resection numbness of lower limbs, each crude drug weight proportion is as follows:
Radix Araliae undulatae 7g, great Ye Rhizoma Drynariae 7g, thick leaf tree 7g, Fructus Platycaryae strobilaceac 7g, Galla Fici lacoris 7g, Radix Ampelopsis delavayanae 7g, golden Caput Felis domestica 7g, Pachysandra axillaris Franch. 7g, Radix Tylophorae Yunnanensis 7g, Radix Glycyrrhizae 7g.
Embodiment 4
Treat a Chinese medicine for Lumbar Disc herniation resection numbness of lower limbs, each crude drug weight proportion is as follows:
Radix Araliae undulatae 8g, great Ye Rhizoma Drynariae 8g, thick leaf tree 8g, Fructus Platycaryae strobilaceac 8g, Galla Fici lacoris 8g, Radix Ampelopsis delavayanae 8g, golden Caput Felis domestica 8g, Pachysandra axillaris Franch. 8g, Radix Tylophorae Yunnanensis 8g, Radix Glycyrrhizae 8g.
Embodiment 5
Treat a Chinese medicine for Lumbar Disc herniation resection numbness of lower limbs, each crude drug weight proportion is as follows:
Radix Araliae undulatae 4g, great Ye Rhizoma Drynariae 4g, thick leaf tree 4g, Fructus Platycaryae strobilaceac 4g, Galla Fici lacoris 4g, Radix Ampelopsis delavayanae 4g, golden Caput Felis domestica 4g, Pachysandra axillaris Franch. 4g, Radix Tylophorae Yunnanensis 4g, Radix Glycyrrhizae 4g.
Carried out clinical pharrnacokinetics test to Chinese medicine of the present invention, Details as Follows:
1 clinical data
1.1 physical data
In treatment group 54 example, man 35 example, female 19 example; Minimum 22 years old of age, maximum 61 years old, average 41.5 years old; L
4-5intervertebral disk hernia 22 example, L
5s
1intervertebral disk hernia 32 example; Outstanding 28 examples in left side, outstanding 26 examples in right side; The course of disease the shortest January, the longest 7 years zero March, average 3 years zero July; Buttocks legs person 20 example, numb person 48 example of lower limb foot, muscular strength subtracts weak person 44 example, and three does not all have person 20 example.In matched group 54 example, man 29 example, female 25 example; Minimum 27 years old of age, maximum 62 years old, average 44.5 years old; L
4-5intervertebral disk hernia 20 example, L
5s
1intervertebral disk hernia 34 example; Left side 21 example, right side 33 example; The course of disease the shortest March, the longest 9 years, average 4 years zero June; Buttocks legs person 22 example, numb person 48 example of lower limb foot, muscular strength subtracts weak person 18 example, and three does not all have person 14 example.
1.2 case inclusive criterias
According to clinical manifestation, CT scan and or MRI check and the decentralized of right proved by operation or non-cauda equina injury type prolapse of lumbar intervertebral disc; Postoperative lumbago and skelalgia is alleviated very soon, check that straight-leg raising test is close to normal, but suffering limb is ached, numbness, muscular strength subtract weak person; Age, sex, race were not limit between 20-65 year.
1.3 case exclusion standards
1. central type or cauda equina injury type prolapse of lumbar intervertebral disc; 2. postoperative suffering limb anacidity pain, numbness and muscular strength weaken; 3. postoperative lower limb radiating pain is without obviously alleviating or increasing the weight of, and leg raising straight is without improver; 4. serious cardiovascular is merged, cerebrovascular, the primary disease that Liver and kidney and hemopoietic system etc. are serious, psychotic.
2 Therapeutic Method
2.1 operative treatment
All cases all at the descending way of escape Nuclectomy of Continuous Epidural Block and lateral crypt Enlargement, postoperative row conventional antiinflammatory and dehydration therapy.
2.2 Therapeutic Method
Treatment group adopts the Chinese medicine of the embodiment of the present invention 1, every day 1 dose, and 2 sub-services sooner or later, 10 doses is 1 course for the treatment of.
Matched group adopts mecobalamin (trade name: methycobal defends pharmaceutcal corporation, Ltd of material China) treatment, 500 μ g, every day 2 times.Two groups of courses for the treatment of are January.Two groups start to carry out Drug therapy for all postoperative 3rd day, and parallel leg raising straight is taken exercise and Go to ground activity under waistline protection, and waistline uses January.
3 criterions of therapeutical effect and result
3.1 criterion of therapeutical effect
According to the Macnab efficacy assessment standard of improvement.Cure: ache, pain and numbness disappears completely, Myodynamia recovery is normal; Effective: even have ache, numb, Myodynamia recovery is close to normal; Effective: disappearance of aching, time have numbness, muscular strength weakens and slightly improves; Invalid: unchanged before and after treatment, even increase the weight of.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study example (%)
| Group | n | Cure | Effective | Effectively | Invalid | Total effective rate |
| Treatment group | 54 | 34(62.96) | 11(20.37) | 6(11.11) | 3(5.56) | (94.45)* |
| Matched group | 54 | 20(37.04) | 11(20.37) | 8(14.81) | 15(27.78) | (72.22) |
Note: compare with matched group, * P<0.05.
Claims (3)
1. treat a Chinese medicine for Lumbar Disc herniation resection numbness of lower limbs, be made up of the Chinese medicine of following weight portion:
Radix Araliae undulatae 4-8 part, great Ye Rhizoma Drynariae 4-8 part, thick leaf tree 4-8 part, Fructus Platycaryae strobilaceac 4-8 part, Galla Fici lacoris 4-8 part, Radix Ampelopsis delavayanae 4-8 part, golden Caput Felis domestica 4-8 part, Pachysandra axillaris Franch. 4-8 part, Radix Tylophorae Yunnanensis 4-8 part, Radix Glycyrrhizae 4-8 part.
2. the Chinese medicine for the treatment of Lumbar Disc herniation resection numbness of lower limbs according to claim 1, is characterized in that, be made up of the Chinese medicine of following weight portion:
Radix Araliae undulatae 5-7 part, great Ye Rhizoma Drynariae 5-7 part, thick leaf tree 5-7 part, Fructus Platycaryae strobilaceac 5-7 part, Galla Fici lacoris 5-7 part, Radix Ampelopsis delavayanae 5-7 part, golden Caput Felis domestica 5-7 part, Pachysandra axillaris Franch. 5-7 part, Radix Tylophorae Yunnanensis 5-7 part, Radix Glycyrrhizae 5-7 part.
3. the Chinese medicine for the treatment of Lumbar Disc herniation resection numbness of lower limbs according to claim 3, is characterized in that, be made up of the Chinese medicine of following weight portion:
Radix Araliae undulatae 6 parts, great Ye Rhizoma Drynariae 6 parts, thick leaf set 6 parts, Fructus Platycaryae strobilaceac 6 parts, Galla Fici lacoris 6 parts, Radix Ampelopsis delavayanae 6 parts, golden Caput Felis domestica 6 parts, Pachysandra axillaris Franch. 6 parts, Radix Tylophorae Yunnanensis 6 parts, 6 parts, Radix Glycyrrhizae.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105943972A (en) * | 2016-06-27 | 2016-09-21 | 沙蕊 | Traditional Chinese medicine composition for treating low back pain after minimally invasive surgery of protrusion of lumbar intervertebral disc |
-
2015
- 2015-10-30 CN CN201510721881.0A patent/CN105194122A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 黄平: "身痛逐瘀汤加减治疗腰椎间盘突出症术后麻木75例", 《实用中西医结合临床》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105943972A (en) * | 2016-06-27 | 2016-09-21 | 沙蕊 | Traditional Chinese medicine composition for treating low back pain after minimally invasive surgery of protrusion of lumbar intervertebral disc |
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Application publication date: 20151230 |