CN105193807A - 用于治疗急性躁狂的氨甲酰基-环己烷类 - Google Patents

用于治疗急性躁狂的氨甲酰基-环己烷类 Download PDF

Info

Publication number
CN105193807A
CN105193807A CN201510549993.2A CN201510549993A CN105193807A CN 105193807 A CN105193807 A CN 105193807A CN 201510549993 A CN201510549993 A CN 201510549993A CN 105193807 A CN105193807 A CN 105193807A
Authority
CN
China
Prior art keywords
application according
compound
formula
treatment
effective dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510549993.2A
Other languages
English (en)
Chinese (zh)
Inventor
I·拉兹洛维斯基
G·尼梅斯
G·安道尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Nyrt
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Publication of CN105193807A publication Critical patent/CN105193807A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201510549993.2A 2007-05-24 2008-05-19 用于治疗急性躁狂的氨甲酰基-环己烷类 Pending CN105193807A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HUP0700370 2007-05-24
HU0700370A HUP0700370A2 (en) 2007-05-24 2007-05-24 Use of (thio)-carbamoyl-cyclohexane derivatives in the manufacture of a medicament for the treatment of acute mania
CN200880017360A CN101678212A (zh) 2007-05-24 2008-05-19 用于治疗急性躁狂的氨甲酰基-环己烷类

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN200880017360A Division CN101678212A (zh) 2007-05-24 2008-05-19 用于治疗急性躁狂的氨甲酰基-环己烷类

Publications (1)

Publication Number Publication Date
CN105193807A true CN105193807A (zh) 2015-12-30

Family

ID=89987541

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201510549993.2A Pending CN105193807A (zh) 2007-05-24 2008-05-19 用于治疗急性躁狂的氨甲酰基-环己烷类
CN200880017360A Pending CN101678212A (zh) 2007-05-24 2008-05-19 用于治疗急性躁狂的氨甲酰基-环己烷类

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN200880017360A Pending CN101678212A (zh) 2007-05-24 2008-05-19 用于治疗急性躁狂的氨甲酰基-环己烷类

Country Status (26)

Country Link
US (1) US20100197704A1 (https=)
EP (1) EP2164572B2 (https=)
JP (1) JP2010527985A (https=)
KR (1) KR20150076266A (https=)
CN (2) CN105193807A (https=)
AU (1) AU2008252621B2 (https=)
CA (1) CA2687528C (https=)
CY (1) CY1113566T1 (https=)
DK (1) DK2164572T4 (https=)
EA (1) EA021936B1 (https=)
ES (1) ES2397962T5 (https=)
GE (1) GEP20135731B (https=)
HR (1) HRP20130092T4 (https=)
HU (1) HUP0700370A2 (https=)
IL (1) IL202048A (https=)
MX (1) MX2009012752A (https=)
MY (1) MY148955A (https=)
NZ (1) NZ582284A (https=)
PL (1) PL2164572T5 (https=)
PT (1) PT2164572E (https=)
RS (1) RS52613B2 (https=)
SI (1) SI2164572T2 (https=)
TW (1) TWI428130B (https=)
UA (1) UA101323C2 (https=)
WO (1) WO2008142463A2 (https=)
ZA (1) ZA200908283B (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0700353A2 (en) * 2007-05-18 2008-12-29 Richter Gedeon Nyrt Metabolites of (thio)carbamoyl-cyclohexane derivatives
US7875610B2 (en) * 2007-12-03 2011-01-25 Richter Gedeon Nyrt. Pyrimidinyl-piperazines useful as D3/D2 receptor ligands
CA2715760C (en) * 2008-02-21 2017-06-13 Mitsubishi Tanabe Pharma Corporation Solid preparation for oral administration of cariprazine hydrochloride
RS53866B1 (sr) 2008-07-16 2015-08-31 Richter Gedeon Nyrt. Farmaceutske formulacije koje sadrže ligande dopaminskih receptora
HU230067B1 (hu) 2008-12-17 2015-06-29 Richter Gedeon Nyrt Új piperazin só és eljárás előállítására
HUP0800765A2 (en) 2008-12-18 2010-11-29 Richter Gedeon Nyrt A new process for the preparation of piperazine derivatives and their hydrochloric salts
HUP0800766A2 (en) 2008-12-18 2010-11-29 Richter Gedeon Vegyeszet Process for the preparation of piperazine derivatives
US9610274B2 (en) * 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
US8912197B2 (en) 2012-08-20 2014-12-16 Forest Laboratories Holdings Ltd. Crystalline form of carbamoyl-cyclohexane derivatives
US11274087B2 (en) 2016-07-08 2022-03-15 Richter Gedeon Nyrt. Industrial process for the preparation of cariprazine
US11547707B2 (en) 2019-04-10 2023-01-10 Richter Gedeon Nyrt. Carbamoyl cyclohexane derivatives for treating autism spectrum disorder

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005012266A1 (en) * 2003-08-04 2005-02-10 Richter Gedeon Vegyészeti Gyár Rt. (thio) carbamoyl-cyclohexane derivatives as d3/d2 receptor antagonists
US7122576B2 (en) * 2001-02-27 2006-10-17 Plata-Salaman Carlos R Carbamate compounds for use in preventing or treating bipolar disorder

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2155200B1 (en) * 2007-05-11 2016-12-07 Richter Gedeon Nyrt. Crystalline form of a carbamoyl-cyclohexane derivative

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7122576B2 (en) * 2001-02-27 2006-10-17 Plata-Salaman Carlos R Carbamate compounds for use in preventing or treating bipolar disorder
WO2005012266A1 (en) * 2003-08-04 2005-02-10 Richter Gedeon Vegyészeti Gyár Rt. (thio) carbamoyl-cyclohexane derivatives as d3/d2 receptor antagonists

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
汪春运等: "不典型抗精神病药治疗情感性精神障碍", 《中国行为医学科学》 *

Also Published As

Publication number Publication date
RS52613B2 (sr) 2018-05-31
GEP20135731B (en) 2013-01-25
HRP20130092T4 (hr) 2016-01-01
CA2687528C (en) 2016-07-05
UA101323C2 (en) 2013-03-25
CY1113566T1 (el) 2016-06-22
CN101678212A (zh) 2010-03-24
IL202048A (en) 2014-11-30
HRP20130092T1 (en) 2013-02-28
EP2164572A2 (en) 2010-03-24
DK2164572T3 (da) 2013-02-11
ES2397962T3 (es) 2013-03-12
WO2008142463A2 (en) 2008-11-27
CA2687528A1 (en) 2008-11-27
WO2008142463A3 (en) 2009-03-05
PT2164572E (pt) 2013-01-28
ZA200908283B (en) 2010-08-25
EA200971087A1 (ru) 2010-04-30
HK1136984A1 (en) 2010-07-16
EP2164572B2 (en) 2015-09-16
KR20150076266A (ko) 2015-07-06
MX2009012752A (es) 2010-03-15
EA021936B1 (ru) 2015-10-30
EP2164572B1 (en) 2012-11-14
TW201002326A (en) 2010-01-16
AU2008252621A1 (en) 2008-11-27
HUP0700370A2 (en) 2009-04-28
PL2164572T3 (pl) 2013-04-30
RS52613B (sr) 2013-04-30
JP2010527985A (ja) 2010-08-19
MY148955A (en) 2013-06-14
NZ582284A (en) 2012-07-27
HU0700370D0 (en) 2007-07-30
SI2164572T1 (sl) 2013-02-28
US20100197704A1 (en) 2010-08-05
TWI428130B (zh) 2014-03-01
IL202048A0 (en) 2010-06-16
ES2397962T5 (es) 2016-01-08
DK2164572T4 (en) 2016-01-04
AU2008252621B2 (en) 2013-09-19
SI2164572T2 (sl) 2016-01-29
PL2164572T5 (pl) 2016-02-29

Similar Documents

Publication Publication Date Title
CN105193807A (zh) 用于治疗急性躁狂的氨甲酰基-环己烷类
Jacobson Clinical manual of geriatric psychopharmacology
EP2958573B1 (en) Pharmaceutical formulations of nitrite and uses thereof
US20130225559A1 (en) S-mirtazapine for the treatment of hot flush
US20240277698A1 (en) Methods of using aldosterone synthase inhibitors
CA3237151A1 (en) Methods and compositions for treating conditions associated with central hypoventilation
JP2022521208A (ja) うつ病及び他の障害の治療のための組成物及び方法
Salamonde et al. Clinical and therapeutic analysis of oncology patients treated at the pain and palliative care program of the Hospital Universitário Clementino Fraga Filho in 2003
TW202535357A (zh) 治療更年期及近更年期之方法
Edan Photo Degradation Of Acitrin®(Cetirizine Dihydrochloride) Under Different Extreme Lighting Condition: An UV Analysis
HK1136984B (en) Carbamoyl-cyclohexanes for treating acute mania
Monira Evaluation of Photo-Degradation of alatrol®(Cetirizine hydrochloride) under different Extreme lighting condition: An UV Analysis
Wines et al. Drug Class Review Alzheimer’s Drugs
KR20100022956A (ko) 급성 조증 치료용 카르바모일-시클로헥산
NZ625863B2 (en) Methods for treatment and prevention of opioid induced constipation using oral compositions of methylnaltrexone

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20151230

WD01 Invention patent application deemed withdrawn after publication