Background technology
The record analysis of electrocardiogram is the important method of overall understanding human heart physiology and pathological state.And the electrocardiographic recorder time is short, unknown cause, accidentally outbreak, the abnormal heart event not easily caught are difficult to be effectively recorded, and strengthen for the early prevention of heart disease, the diagnosis and treatment difficulty of difficult and complicated illness.Along with the fast development of the technology such as microelectronics, super large-scale integration, microsensor, miniature power supply device, micro memory, the medical instruments and equipment of record electrocardiogram is tending towards microminiaturized, portable, long time phasing.
Chinese invention patent application CN104545885A discloses a kind of SMD dynamic electrocardiogram recording instrument, comprise housing and comprise housing and be arranged on crosslinking electrode, electrocardiosignal modulate circuit, acceleration transducer, the microprocessor in described housing, disclosing the means identifying motion artifacts is 3-axis acceleration sensors, its date storage method: first in relief area write data, again data are write SD card after relief area is full.Collection due to electrocardiogram (ECG) data continues to carry out, if write a small amount of data frequently in memory device, directly can increase system power dissipation.
Chinese invention patent application CN103099615A discloses a kind of method and the device of eliminating exercise electrocardiogram signal interference, and describing its reference signal collecting unit of knowing clearly is acceleration transducer.Chinese invention patent application CN101999936A discloses a kind of signal sensing device of tool noise cancellation, utilizes accelerometer to eliminate the dynamic noise in electrocardiosignal.Motion artifacts be in dynamic electrocardiogram drawing system the most generally, the most unmanageable noise jamming type, having become current affects one of dynamic electrocardiogram map interpretation accuracy and the main factor of diagnosis efficiency.The research of prior art to ambulatory electrocardiogram motion artifacts treatment technology mainly concentrates on how effectively to eliminate motion artifacts, and ignores crucial motion artifacts recognition technology.
In addition, for the demand for development of modern medical service theory, radio communication will be deep into medical system, can serve more efficiently for people provide.In recent years, portable medical has developed into an important branch in electron medical treatment field, along with the arriving in 3G, 4G epoch and smart mobile phone, panel computer universal, medical data will focus on intelligent mobile terminal gradually, and the cloud realizing electronic databank stores and remote diagnosis.Therefore, electrocardiogram can be shown on mobile terminals, stores and analyze, there is profound significance.
Therefore, develop a low-power consumption, and electrocardiogram can be shown on intelligent mobile terminal, stores and analyze, takes into account remote medical consultation with specialists simultaneously, and the sticking type dynamic electrocardiogram recording instrument of motion artifacts and the forward-looking meaning of system thereof can be identified when analytical data.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of sticking type dynamic electrocardiogram recording instrument and system thereof of low-power consumption.
For solving the problems of the technologies described above, the invention provides a kind of sticking type dynamic electrocardiogram recording instrument, comprising housing and the signals collecting be arranged in described housing and memory module, motion monitoring module, data transmission module and power management module, wherein,
Described signals collecting and memory module, receive the outside electrocardiosignal transmitted;
Described motion monitoring module comprises 3-axis acceleration sensor, and the 3-axis acceleration value that described motion monitoring module obtains the generation of described 3-axis acceleration sensor is sent to described signals collecting and memory module;
Data transmission module is connected with described signals collecting and memory module;
Power management module, comprises rechargeable battery, and described power management module monitors the information about power of described rechargeable battery, and provides electric power for described signals collecting and memory module, described motion monitoring module and described data transmission module;
Wherein, described signals collecting and memory module comprise electrocardiosignal amplification module, MCU control module and data memory module, described electrocardiosignal amplification module carries out operation amplifier and filtering to the described electrocardiosignal received, described MCU control module receives the described electrocardiosignal of described electrocardiosignal amplification module transmission and is converted to electrocardiogram (ECG) data, described MCU control module also receives the described 3-axis acceleration value of described motion monitoring module transmission and is converted to described exercise intensity data, described electrocardiogram (ECG) data and described exercise intensity data are stored in described data memory module, the described electrocardiogram (ECG) data that described data memory module stores and described exercise intensity data can outwards send by data transmission module,
Described data memory module comprises FRAM memorizer and eMMC memorizer, the described electrocardiogram (ECG) data received and described exercise intensity data are stored on described FRAM memorizer by described data memory module, be stored into after a setting capacity described electrocardiogram (ECG) datas all on described FRAM memorizer and described exercise intensity data be stored on described eMMC memorizer until described FRAM memorizer.
According to one embodiment of present invention, before described FRAM memorizer is not stored into described setting capacity, described eMMC memorizer is in closed condition.
According to one embodiment of present invention, described signals collecting and memory module also comprise gauge tap and display module, wherein,
Described gauge tap is used for allowing user input instruction;
Described MCU control module connects described gauge tap, enters different mode of operations according to described instruction;
Described display module connects described MCU control module.
According to one embodiment of present invention, when described instruction is the first instruction, described MCU control module enters normal mode of operation, described MCU control module is analyzed described electrocardiogram (ECG) data by electrocardio recognizer, when the described electrocardiogram (ECG) data of discovery is abnormal, then outwards send described electrocardiogram (ECG) data by described data transmission module; When described instruction is the second instruction, described MCU control module enters mark function pattern, described MCU control module is processed described electrocardiogram (ECG) data by the triggering mode of catching described gauge tap, be marked at the described electrocardiogram (ECG) data being stored into described data memory module triggered before and after described gauge tap in certain hour section, after R ripple being detected, produce a high level signal to described display module; When described instruction is the 3rd instruction, described MCU control module enters park mode, is in described park mode by sticking type dynamic electrocardiogram recording instrument described in described display module reminding user.
According to one embodiment of present invention, described in described motion monitoring module gather in regular hour T three groups, 3-axis acceleration value is sent to described MCU control module, cumulatively after high-pass filtering and low-pass filtering obtains described exercise intensity data and also stores; Wherein,
Described low-pass filtering adopts median filtering method, and the formula of described high-pass filtering is:
Pn=ΔP+a·Pn-1
Wherein, Δ P is the difference of current acceleration sampled value and last acceleration sampled value Pn-1, and Pn is the value after described high-pass filtering; Parameter a depends on the cut-off frequency of high-pass filtering.
According to one embodiment of present invention, described motion monitoring module is by SPI interface or I
2c interface is connected with described MCU control module.
Present invention also offers a kind of sticking type dynamic electrocardiogram recording instrument system, comprise electrode, charging and digital independent upload device, mobile terminal, and any one sticking type dynamic electrocardiogram recording instrument aforementioned, described electrode gathers electrocardiosignal and is sent to described signals collecting and memory module, described charging and digital independent are uploaded device and are connected to read described electrocardiogram (ECG) data and described exercise intensity data that described signals collecting and memory module store with described signals collecting and memory module, described charging and digital independent are uploaded device and are also connected to charge to described rechargeable battery with described power management module, described mobile terminal can carry out both-way communication with described data transmission module.
According to one embodiment of present invention, also comprise PC, described PC and described charging and digital independent are uploaded device and are connected to obtain described electrocardiogram (ECG) data and described exercise intensity data by USB port mode, can obtain diagnosis report after the application software process through described PC runs.
According to one embodiment of present invention, described mobile terminal opens specific program to connect described data transmission module, receives and processes the described electrocardiogram (ECG) data and described exercise intensity data that are obtained by described data transmission module.
According to one embodiment of present invention, also comprise far-end server, described digital independent is uploaded device, by radio network router, described electrocardiogram (ECG) data and described exercise intensity data is sent to described far-end server.
Sticking type dynamic electrocardiogram recording instrument provided by the invention and system thereof have low-power consumption and identify motion artifacts function, and electrocardiogram can be shown on mobile terminals, stores and analyze, and take into account remote medical consultation with specialists simultaneously.
Detailed description of the invention
Below in conjunction with specific embodiments and the drawings, the invention will be further described; set forth more details in the following description to fully understand the present invention; but the present invention obviously can implement with multiple this alternate manner described that is different from; those skilled in the art can when doing similar popularization, deduction without prejudice to when intension of the present invention according to practical situations, therefore should with content constraints protection scope of the present invention of this specific embodiment.
Fig. 1 is the structured flowchart of an embodiment of sticking type dynamic electrocardiogram recording instrument of the present invention.Fig. 2 is the structured flowchart of signals collecting of the present invention and memory module.As depicted in figs. 1 and 2, a kind of sticking type dynamic electrocardiogram recording instrument 100 comprises housing (not shown) and the signals collecting be arranged in housing and memory module 110, motion monitoring module 120, data transmission module 130 and power management module 140.
Signals collecting and memory module 110 receive the electrocardiosignal transmitted outside and are converted to electrocardiogram (ECG) data and store, and the electrocardiosignal that outside is transmitted is the signal gathered by the electrode attaching human body.
Motion monitoring module 120 comprises 3-axis acceleration sensor 121, motion monitoring module 120 obtains 3-axis acceleration value that 3-axis acceleration sensor 121 produces and to be sent in signals collecting and memory module 110 and to be converted to exercise intensity data and to store, and 3-axis acceleration value here refers to multiple sampled values of 3-axis acceleration.
Data transmission module 130 is connected with signals collecting and memory module 110, and the electrocardiogram (ECG) data that signals collecting and memory module 110 store and exercise intensity data can outwards send by it.Data transmission module 130 can adopt Bluetooth communication protocol, and the data transmission module 130 of low-power consumption can realize the both-way communication carrying out data with the mobile terminal of the Bluetooth transmission function with low-power consumption of outside, hereinafter describes in detail.
Power management module 140, comprises rechargeable battery 141, can be chargeable lithium cell.Power management module 140 monitors the information about power of rechargeable battery 141, and provides electric power for signals collecting and memory module 110, motion monitoring module 120 and data transmission module 130.
Wherein, signals collecting and memory module 110 comprise electrocardiosignal amplification module 111, MCU control module 112 and data memory module 113, electrocardiosignal amplification module 111 electrocardiosignal be responsible for receiving carries out operation amplifier and filtering, MCU control module 112 is responsible for the electrocardiosignal of reception electrocardiosignal amplification module 111 transmission and is converted to electrocardiogram (ECG) data, and MCU control module 112 also receives the 3-axis acceleration value of motion monitoring module 120 transmission and is converted to exercise intensity data.Electrocardiogram (ECG) data and exercise intensity data are stored in data memory module 113.
Data memory module 113 comprises FRAM memorizer 1131 and eMMC memorizer 1132.The electrocardiogram (ECG) data of reception and exercise intensity data are stored on FRAM memorizer 1131 by data memory module 113, be stored into after a setting capacity electrocardiogram (ECG) datas all on FRAM memorizer 1131 and exercise intensity data be stored on eMMC memorizer 1132 until FRAM memorizer 1131.
Data memory module 113 have employed FRAM memorizer 1131 and combines and the form of depositing with eMMC memorizer 1132.FRAM memorizer 1131 utilizes the ferroelectric effect of ferroelectric crystal to realize data and stores, and equally can use, have non-volatile storage characteristics with common ROM memorizer.Feature is that speed is fast, and can operate as RAM, read-write power consumption is extremely low, there is not the problem of the maximum write number of times as E2PROM.EMMC memorizer 1132 is made up of an embedded storage solution, with MMC (multimedia card) interface, flash memory device and master controller, all elements are all in a small-sized BGA package, be equivalent to Flash and control circuit to be packaged together, function class is like SD card.But owing to being BGA package, eMMC memorizer 1132 volume is much little.The advantage of eMMC memorizer 1132 is simplified system designs, reduces system bulk.The power consumption of FRAM memorizer 1131 is several uA, and the power consumption of eMMC memorizer 1132 will reach about 200uA, and the access times therefore reducing eMMC memorizer 1132 reduce the essential condition of whole system power consumption.Because the gatherer process of electrocardiogram (ECG) data continues to carry out, if directly store data in eMMC memorizer 1132, then can frequently access eMMC memorizer 1132, and need a direct-open eMMC memorizer 1132, and only store a small amount of data, the actual power consumption produced is very large at every turn.In the present embodiment, be first stored in by electrocardiogram (ECG) data in FRAM memorizer 1131, at this moment eMMC memorizer 1132 is in closed condition, does not have power consumption.Deposit after enough certain spaces until FRAM memorizer 1131 and again eMMC memorizer 1132 is opened, and be transplanted on eMMC memorizer 1132 by unified for data, the access times of eMMC memorizer 1132 can be reduced like this, extend the service life of eMMC memorizer 1132 and reduce power consumption.Preferably, eMMC memorizer 1132 adopts the capacity of 4GByte, can meet the demand of massive store.
Signals collecting and memory module 110 also comprise gauge tap 114 and display module 115.Display module 115 can be LED display module.Gauge tap 114 is for allowing user input instruction.MCU control module 112 connection control switch 114, enters different mode of operations according to the instruction that gauge tap 114 receives.Display module 115 connects MCU control module 112, receives the instruction that MCU control module 112 sends.
The instruction received when gauge tap 114 is the first instruction, MCU control module 112 enters normal mode of operation, MCU control module 112 is analyzed electrocardiogram (ECG) data by electrocardio recognizer, when discovery electrocardiogram (ECG) data is abnormal, then outwards sends electrocardiogram (ECG) data by data transmission module 130.
The instruction received when gauge tap 114 is the second instruction, and MCU control module 112 enters mark function pattern.When instruction is the second instruction, MCU control module 112 enters mark function pattern.MCU control module 112 is processed electrocardiogram (ECG) data by the triggering mode of catching gauge tap 114, be marked at the electrocardiogram (ECG) data being stored into data memory module 113 before and after trigging control switch 114 in certain hour section, a high level signal is produced to display module 115 after R ripple being detected, change into optical signal intuitively, facilitate user to detect in real time R ripple and T ripple.Understandable, the triggering mode of gauge tap 114 refers to and can judge to enter the electrocardiogram (ECG) data in different working modes or mark triggers surrounding time according to the length in triggered time and/or continuous trigger number of times.
The instruction received when gauge tap 114 is the 3rd instruction, and MCU control module 112 enters park mode, and the sticking type dynamic electrocardiogram recording instrument 100 current by display module 115 reminding user is in park mode.
In order to whether the user of monitoring sticking type dynamic electrocardiogram recording instrument 100 is kept in motion, the intensity of motion how, and identifying motion artifacts, three groups of 3-axis acceleration values that motion monitoring module 120 gathers in regular hour T are sent to MCU control module 112.MCU control module 112 is cumulative after high-pass filtering and low-pass filtering to be obtained exercise intensity data and stores; Wherein, low-pass filtering adopts median filtering method, and the formula of high-pass filtering is:
Pn=ΔP+a·Pn-1
Wherein, Δ P is the difference of current acceleration sampled value (X-axis, Y-axis or Z axis) and last acceleration sampled value Pn-1, and Pn is the value after high-pass filtering; Parameter a depends on the cut-off frequency of high-pass filtering.
Because the disposal ability of MCU control module 112 is limited, the algorithm of intensive can not be completed.Therefore calculated by MCU control module 112 and judge that the kinestate result that obtains is little to reducing the income that motion artifacts brings.In addition, want to obtain kinestate accurately, need higher acceleration sample rate, be i.e. all complete the recording of the acceleration of three axles, but a huge data volume can be produced like this, even also many than electrocardiogram (ECG) data.Therefore above-mentioned data reduction algorithm is devised to reduce memory data output and to reach the effect judging motion artifacts.Because for the motion artifacts judging electrocardiosignal, the direction of acceleration is unessential, only need to judge within the scope of certain hour, whether accekeration has exceeded certain threshold value, and by the fore-aft acceleration state of value of the point that exceedes threshold value and persistent period, judge the kinestate of user in conjunction with electrocardiogram (ECG) data.Low-pass filtering adopts median filtering method for removing the High-frequency Interference in acceleration gatherer process, and high-pass filtering is used for getting rid of gravity acceleration g.Three groups of filtered values of X, Y, Z axis all in T time be accumulated in together, the value obtained can reflect the exercise intensity of user, and does not need the direction of motion, and this exercise intensity value is stored in data memory module 113.Wherein, the size of T value, directly affect the sensitivity that exercise intensity judges, T is less, and sensitivity is higher, but data volume is larger.
By this algorithm, substantially can come out the basic exercise intensity of user, and data volume contrasts with accekeration record three axles completely and will reduce a lot.In the overlength time-histories dynamic ECG analysis software of the PC mentioned afterwards, the exercise intensity data stored can be read out, medical worker can according to the state of the electrocardiogram (ECG) data of user, dynamic conditioning judges the threshold value of motion artifacts, thus more accurately and targetedly judge motion artifacts, by analysis after editor, obtain more pure electrocardiogram (ECG) data accurately.
Preferably, motion monitoring module 120 is connected with MCU control module 112 by SPI interface or I2C interface.
Invention further describes a kind of sticking type dynamic electrocardiogram recording instrument system.Fig. 3 is the structured flowchart of an embodiment of sticking type dynamic electrocardiogram recording instrument system of the present invention.As shown in the figure, sticking type dynamic electrocardiogram recording instrument system 200 comprises electrode 210, charging and digital independent and uploads device 220, mobile terminal 230, and aforesaid any one sticking type dynamic electrocardiogram recording instrument 100.Electrode 210 adopts disposable electrode sheet.Disposable electrode sheet soft comfortable, easy to use, need not sterilize, firm pasting, can cross infection be avoided.Disposable electrode sheet can adopt button to be connected with sticking type dynamic electrocardiogram recording instrument 100, is convenient for changing.In order to skin of better fitting, electrode 210 profile that the present invention uses adopts the design similar to the bottom shape of the shell of sticking type dynamic electrocardiogram recording instrument 100.Electrode 210 is for gathering electrocardiosignal and being sent to signals collecting and the memory module 110 of the sticking type dynamic electrocardiogram recording instrument 100 in Fig. 2.
Charging and digital independent are uploaded device 220 and are connected to read electrocardiogram (ECG) data and exercise intensity data that data memory module 113 stores with signals collecting and memory module 110, charge and digital independent is uploaded device 220 and is also connected to charge to rechargeable battery 141 with power management module 140.It is external device (ED) independent of sticking type dynamic electrocardiogram recording instrument 100 that charging and digital independent upload device 220, rechargeable battery 141 is built-in with in sticking type dynamic electrocardiogram recording instrument 100, and on shell, reserved charging and digital independent contact, monitor need charging or the electrocardiogram (ECG) data that needs to read on data memory module 113 and exercise intensity data time, monitor can be placed on charging and digital independent upload on the fixed position of device 220, the metal spring contacts that charging and digital independent are uploaded on device 220 contacts with the contact that monitor picks out, thus complete charging or digital independent.
Mobile terminal 230 can carry out both-way communication with the data transmission module 130 of sticking type dynamic electrocardiogram recording instrument 100.Data transmission module 130 can adopt Bluetooth communication protocol, to realize the both-way communication carrying out data with the mobile terminal 230 with low-power consumption Bluetooth transmission function.Data transmission module 130 can be broadcasted after starting automatically, the mobile terminal 230 having opened application-specific can scan this data transmission module 130 and dock, and just can be monitored this data transmission module 130 by low-power consumption Bluetooth protocol after success.MCU control module 112 processes the data of rear storage can by data transmission module 130 Bulk transport in the analysis application of mobile terminal 230.Analysis application can to data after receiving data, comprise electrocardiogram (ECG) data and exercise intensity data to carry out processing, store, show, and certain segment data of specifying can be uploaded to the far-end server that it connects according to the operation of application program operator, also can arrange when electrocardiosignal is analyzed go out exception time automatically upload this part electrocardiogram (ECG) data be labeled or warning message to programmed emergency or relevant departments.
Preferably, sticking type dynamic electrocardiogram recording instrument system 200 also comprises PC 240.PC 240 is uploaded device 220 with charging and digital independent and is connected to obtain electrocardiogram (ECG) data and exercise intensity data by USB port 241, can obtain diagnosis report after the application software process through PC 240 runs.This application software can be overlength time-histories dynamic ECG analysis software, mainly management and the electrocardiogram (ECG) data of analyzing stored on sticking type dynamic electrocardiogram recording instrument 100.The USB port that sticking type dynamic electrocardiogram recording instrument 100 is uploaded on device 220 by charging and digital independent communicates with PC 240, in the overlength time-histories dynamic ECG analysis software that the digital independent be stored on monitor is installed to PC 240, individual case can be set up to the data read, can be inquired about by accounts information, look back and editor's case, the different hearts is clapped type and is comprised normally, room early, Fang Zao, artifact, show by different colors, the kinestate be recorded on electro-cardiograph is read in software, judge that the threshold value of motion artifacts can manual adjustments.Can select high-pass filtering and low-pass filtering to electrocardiogram (ECG) data, the time span of changeable every type page electrical waveform display, can select display gain and chart drive speed, also can check case statistical data and be clinical report editor.Whole electrocardiosignal, kinestate and Relevant Analysis, data, the charts continuously of overlength time-histories dynamic cardiograph analysis system display electro-cardiograph record, comprise omnidistance heart rate trendgram (with per minute, 30 seconds, 1 second equal time statistics), R-R interval rectangular histogram, flag event electrocardiogram; Adopt mouse or keyboard man-machine conversation mode input parameter and instruction; Carry out ambulatory ECG analysis, complete the process such as confirmation, amendment, editor, finally generate diagnosis report.Overlength time-histories ambulatory ECG analysis software can be equipped with laser printer complete edit ambulatory electrocardiogram word, data, chart report and the printing of accompanying drawing.Examining report comprises patient information, record start, end time, actual effectively analysis time, total heart beats, room is sum early, room is sum early, the time of the fastest and the slowest heart rate and generation, average heart rate, room is early (single, in pairs, bunchiness) number of times and proportion, room is early (single, in pairs, bunchiness) number of times and proportion, bradycardia number of times and proportion, the longest bradycardia continues and time of origin, stop fight number of times and proportion, the longest asystolic interval continues and time of origin, clinical report conclusion, hour statistics of analysis result, the clinical diagnosis list of patient indicia's event and electrocardiogram figure bar, heart rate/abnormal heartbeat trendgram, R-R interval rectangular histogram etc.
Preferably, sticking type dynamic electrocardiogram recording instrument system 200 also comprises far-end server 250, and electrocardiogram (ECG) data and exercise intensity data are sent to far-end server 250 by wireless router 260 by the wireless network module that charging and digital independent are uploaded in device 220.Charging and digital independent are uploaded in device 220 can built-in wifi (802.11) wireless network module, in the sphere of action of wireless routing, the data read out, can also by being arranged on charging and the digital independent control of uploading on device 220 is uploaded button and directly uploaded to far-end server 250 by wifi wireless network except being transferred to PC 240 by USB line.Wireless network module can adopt the SmartConnectSAMW25 of Atmel company, it provide the single source unified platform that incorporates low-power consumption microcontroller, hardware security and the wireless connecting function through FCC certification, it is the safe wireless MCU module of complete or collected works' molding, possess aerial upgrade function, wireless and complexity that is security solution can be reduced.
The data memory module of the sticking type dynamic electrocardiogram recording instrument that the present invention describes and system thereof adopts FRAM memorizer and eMMC memorizer and the form of depositing, first electrocardiogram (ECG) data and exercise intensity data are stored in FRAM, deposit after the setting capacity that gets at by these data migrations on eMMC memorizer, minimizing power consumption can be reached, extend the effect of using life of storage.The motion monitoring module adopted, motion artifacts situation can be analyzed according to the accekeration of three axles, unique algorithm for MCU Controller gain variations, carries out filtering to the acceleration information collected, and greatly reduces the memory space of data on the basis accurately judging exercise intensity.
Although the present invention with preferred embodiment openly as above, it is not for limiting the present invention.Any those skilled in the art without departing from the spirit and scope of the present invention, can make possible variation and amendment.Therefore, every content not departing from technical solution of the present invention, any amendment done above embodiment according to technical spirit of the present invention, equivalent variations and modification, all fall within protection domain that the claims in the present invention define.