CN105169561A - Cancer treatment device - Google Patents
Cancer treatment device Download PDFInfo
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- CN105169561A CN105169561A CN201510550739.4A CN201510550739A CN105169561A CN 105169561 A CN105169561 A CN 105169561A CN 201510550739 A CN201510550739 A CN 201510550739A CN 105169561 A CN105169561 A CN 105169561A
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Abstract
The invention provides a cancer treatment device. The cancer treatment device comprises a magnetic amplifier, a Hall element, a magnetic field amplification detection circuit, a pressure-sensitive member, a pulse acceleration detection circuit, a frequency control circuit and a power supply circuit. The frequency control circuit outputs frequency-gradually-changing pulse signals; and the pulse signals act on the magnetic amplifier to generate extremely-thin magnetic force beams, and the magnetic force beams are allowed to be vertically projected to a tumor block in the body of a patient. The pressure-sensitive member and the pulse acceleration detection circuit as well as the Hall element and the magnetic field amplification detection circuit are used for detecting whether the tumor block has resonance; and when the tumor block has resonance, frequency of the pulse signals is locked through the frequency control circuit, and continuous treatment is carried out on the disease part to enable the tumor block to be heated to 70 DEG and above so as to kill cancer cells. Compared with the tumor operation cutting, the cancer treatment device is more flexible in cancer treatment; and independent scanning and treatment can be carried out on blood-supply channels by utilizing the selectivity of higher tumor magnetic resonance, and thus relapse possibility can be avoided basically.
Description
Technical field
The present invention relates to a kind of the action of a magnetic field that utilizes in the therapy equipment of human body, specifically a kind for the treatment of of cancer device.
Background technology
Cancer is one of disease kind that sickness rate is the highest, mortality rate is the highest in recent years, at every moment threatens the life of the mankind, although existing various medical science and technology worker, in order to capture this difficulty and unremitting struggling; But due to its paathogenic factor become more diversified, complicated and normalization, incidence probability is improved year by year, great harm is caused to the life of the mankind.
The pathogeny of cancer has different sayings and foundation separately in the traditional Chinese medical science and doctor trained in Western medicine research field.The traditional Chinese medical science generally believes: cancerous cell is anaerobic cell, likes the environment of anoxia; People due to pressure, anxiety, indignation, depression, animosity, feelings will relax etc. reason cause vivotoxin to be piled up, cannot normally discharge, the toxin expelling hematopoietic functions such as liver, kidney, large intestine, spleen are subject to badly damaged, destroy the equilibrium between yin and yang of each Iarge-scale system of human body, provide cancerous cell grow environment and carcinogenic.Doctor trained in Western medicine is then thought: human body causes the dysregulated gene expression of normal DNA molecule because taking in more biological virus carcinogen, or carcinogenic because of the factor such as hypoimmunity, immune dysfunction; But doctor trained in Western medicine thinks that cancerous cell is anaerobic cell too.
The pathogeny of above-mentioned two kinds of cancers all has its reason and foundation.Research shows, cancerous cell is the minimum biological virus gene of a kind of DNA password.International Medical in 2000 is organized associating various countries to check order to human DNA and is confirmed, the DNA molecular of human body is a very huge keying sequence; And reach a conclusion, the differentiation of large password DNA is very slow, and little password DNA breaks up then very fast, and what cancer later stage cancer cell hyperplasia this also can be interpreted as is exceedingly fast.
Modern medicine has proved that DNA differentiation again copies one (password-base pair) exactly and to put in order identical new DNA molecular on the basis of original password.At human body, this 70% is inevitably there is various biological virus in liquid environment, also various motion (comprising Brownian movement) is certainly existed, the minimum viral DNA of password once put in order with the base pair of a certain section in human normal DNA molecular, positive-negative polarity (acid or alkali) completely to corresponding just can generate a new viral DNA, and differentiation is continued on the basis of normal DNA, also just destroy original cryptography architecture (i.e. doctor trained in Western medicine say dysregulated gene expression) of normal DNA simultaneously; The chromosome seen under light microscopic progressively increases with the increase of viral DNA quantity, and causes the change of human normal cell.Normocellular karyon only accounts for 1/4 of cells intact, and the nucleus of canceration can increase to equally large or generate double-core even multinuclear (being medically called polyploid cell) with cells intact; Simultaneously because the password of viral gene is minimum, proportion is comparatively large, therefore the proportion of whole cancerization cell can increase to Normocellular 2-4 doubly.
Current medical circle generally believes that excision is one of good method of Therapeutic cancer, but surgical excision for cancer middle and advanced stage patient late.Because the malignant tumor hypertrophy of middle and advanced stage is exceedingly fast, must also need nutrient delivery approach faster, this transport way is medically called angiogenesis factor, and this forms the factor if broken up by normal cell (great DNA) password, obviously the needs of the cancerous cell rapid multiplication of rapid multiplication can not be adapted to, therefore the blood supply factor can only be generated by the viral gene of minimum DNA password, therefore will cause the result that the tumor of having excised recurs again.
Medical experiment has confirmed that cancerous cell will be thoroughly dead when temperature is more than 70 DEG C, Beijing Zeng Youyijia research institution develops with American Association and a kind of directly penetrate skin with ox hair acupuncture needle and to insert on cancerous protuberance block and give heating by micro-electric current and kill cancerous cell, and achieves obvious curative effects; But due to some imperfection of enforcement of its method, and selectivity underaction, lethal effect is still had to normal cell, does not therefore still popularize so far.
Summary of the invention
Object of the present invention is just to provide a kind for the treatment of of cancer device, and this device adopts superfine magnetic force bundle to act on cancerous protuberance block place, and magnetic force bundle and cancerous protuberance block is formed resonate, and makes cancerous protuberance block produce high temperature from inside to outside, thus kill cancerous cell by resonance.
The present invention is achieved in that a kind for the treatment of of cancer device, comprising:
Magnetic amplifier, connects with frequency control circuit, for generation of magnetic field, to act on the cancerous protuberance block in patient body from the body surface of patient;
Hall element, connects with magnetic field amplification detection circuit, for being arranged on body surface place corresponding to cancerous protuberance block in patient body, and the field signal at cancerous protuberance block place during to detect treatment, and detection signal is converted into the signal of telecommunication and exports to magnetic field amplification detection circuit;
Magnetic field amplification detection circuit, connects with described Hall element and frequency control circuit respectively, after the situation that magnetic field strengthens appears in cancerous protuberance block place in patient body, exports magnetic field enhancing signal to frequency control circuit;
Pressure cell, accelerates detection circuit with pulse and connects, for detecting pulse during patient treatment, and detection signal is converted into the signal of telecommunication export to pulse accelerate detection circuit;
Pulse accelerates detection circuit, connects respectively with described pressure cell and frequency control circuit, after there is acceleration situation patient pulse, exports pulse signal for faster to frequency control circuit;
Frequency control circuit, accelerate detection circuit with described magnetic amplifier, described magnetic field amplification detection circuit and described pulse respectively to connect, for to magnetic amplifier output frequency being the gradual change pulse signal of 1 ~ 100Hz, magnetic amplifier is made to produce the magnetic field for the treatment of, and when receiving pulse signal for faster or magnetic field enhancing signal, lock the pulse signal frequency this moment exported, continue to described magnetic amplifier the pulse signal exporting locking frequency; And
Power supply, accelerates detection circuit, described magnetic field amplification detection circuit and described magnetic amplifier for giving described frequency control circuit, described pulse and provides required running voltage.
Described magnetic amplifier comprises main coil and the magnetic amplification coil of series connection mutually, described magnetic amplifies coil winding on an annular core, described main coil is wound on an open core, described main coil passes perpendicularly through the center of described annular core at the magnetic line of force that the opening place of described open core produces, and launches magnetic field by the opening part of open core to the cancerous protuberance block in patient body.
The circuit structure that described pulse accelerates detection circuit is: the in-phase input end of amplifier IC13 connects with described pressure cell through electric capacity C27, the 14th foot input of the outfan linkage counter IC14 of amplifier IC13; The 2nd foot outfan of enumerator IC14 connects the first charge circuit be made up of manostat IC5, resistance R43 and electrochemical capacitor C31, and the outfan of the first charge circuit connects the in-phase input end of amplifier IC15 through resistance R51; The 4th foot outfan of enumerator IC14 connects the second charge circuit be made up of manostat IC6, resistance R44 and electrochemical capacitor C32, the outfan of the second charge circuit connects the inverting input of amplifier IC15 through resistance R50, the outfan of amplifier IC15 connects the input anode of optocoupler GO5; The 7th foot outfan of enumerator IC14 connects the base stage of audion Q7 through resistance R56, the colelctor electrode of audion Q7 connects the input cathode of optocoupler GO5, and the output head anode of optocoupler GO5 connects with described frequency control circuit; The 10th foot outfan of enumerator IC14 divides two-way, one tunnel connects with the base stage of audion Q5 through resistance R40, another road connects with the base stage of audion Q6 through resistance R39, the colelctor electrode of audion Q5 connects the outfan of the first charge circuit through electricity group R47, the colelctor electrode of audion Q6 connects the outfan of the second charge circuit through electricity group R46; The 1st foot outfan of enumerator IC14 connects the 15th pin preset end of enumerator IC14 through diode D10, the 15th pin preset end of enumerator IC14 is connected to electrification reset electric capacity C33.
The circuit structure of described magnetic field amplification detection circuit is: the in-phase input end of power discharging IC 11 connects the 2 foot outfans of Hall element H1A through electric capacity C25, the outfan of power discharging IC 11 connects the 3rd charge circuit be made up of resistance R48 and electric capacity C26, diode D9 is parallel with between the two ends of resistance R48, the resistance R48 of the 3rd charge circuit and the connected node of electric capacity C26 connect the in-phase input end of amplifier IC16 through resistance R22, the inverting input of amplifier IC16 connects by manostat IC4, the quiescent potential regulating circuit that resistance R45 and resistance R41 forms, the inverting input of amplifier IC16 connects with the connected node of resistance R45 and resistance R41, the outfan of amplifier IC16 connects with the input anode of optocoupler GO4 through resistance R42, and the output head anode of optocoupler GO4 connects with described frequency control circuit, the input cathode of optocoupler GO4 and the equal earth lead of negative pole of output end.
The circuit structure of described frequency control circuit is: the frequency conversion outfan of single-chip microcomputer IC2 connects the base stage of audion Q1 through resistance R18, the grounded emitter line of audion Q1, the colelctor electrode of audion Q1 connects the constant-current source circuit be made up of resistance R17, resistance R14, manostat IC3 and resistance R16; Electrochemical capacitor C1 is parallel with at the two ends of resistance R14, the positive pole of electrochemical capacitor C1 connects with the input anode of optocoupler GO2, the negative pole of electrochemical capacitor C1 connects with the input cathode of optocoupler GO1, and the input cathode of optocoupler GO2 connects with the input anode of optocoupler GO1; Output head anode contact resistance R4, diode D3 and the oscillating capacitance C6 successively of optocoupler GO2, the minus earth line of oscillating capacitance C6, the positive pole of oscillating capacitance C6 connects with the positive pole of diode D3, and the negative pole of output end of optocoupler GO2 connects with the 7 foot discharge ends of IC1A on time base apparatus; The negative pole of output end of optocoupler GO1 is connected to the positive pole of oscillating capacitance C6 through diode D2, and the negative pole of diode D2 connects with the positive pole of oscillating capacitance C6, the output head anode of optocoupler GO1 through resistance R3 with time base apparatus IC1A 7 foot discharge ends connect; Time base apparatus, the 8 foot power ends of IC1A connected the DC source of 12V, and time base apparatus IC1A 8 foot power ends connect with the positive pole of oscillating capacitance C6 after resistance R6 and resistance R2, the connected node of resistance R6 and resistance R2 connects with the 7 foot discharge ends of IC1A on time base apparatus; Time base apparatus IC1A 6 foot high level trigger ends and 2 foot low level trigger ends all connect with the positive pole of oscillating capacitance C6; Time base apparatus, the 3 foot outfans of IC1A were received in the base stage of audion Q3 and the base stage of audion Q4 respectively after resistance R5, connect with the grid of field effect transistor Q2 after audion Q3 is connected with the emitter stage of audion Q4, the source ground line of field effect transistor Q2, the magnetic that the drain electrode of field effect transistor Q2 connects in described magnetic amplifier successively amplifies coil L1 and main coil L2.
The frequency conversion outfan output frequency of single-chip microcomputer IC2 is from the pulse-width signal of 1 ~ 100Hz gradual change, described pulse accelerates the outfan of detection circuit and the outfan of described magnetic field amplification detection circuit is connected respectively on two inputs of single-chip microcomputer IC2, after single-chip microcomputer IC2 receives the pulse signal for faster being accelerated detection circuit output by described pulse or the magnetic field enhancing signal exported by described magnetic field amplification detection circuit, namely lock the frequency of now pulse-width signal, and export the pulse-width signal after locking frequency by the frequency conversion outfan of single-chip microcomputer IC2.
The pulse-width signal of 1 ~ 50Hz is exported according to setting cycle automatically by the frequency conversion outfan of single-chip microcomputer IC2, and the pulse-width signal of 50 ~ 100Hz is that frequency raise button by connecting with single-chip microcomputer IC2 and frequency reduce button and manually export when exporting.
Magnetic amplifies coil L1 and main coil L2 and forms series arm, one termination 24V DC source of this series arm, another termination field effect transistor Q2, be parallel with by diode D1 and electric capacity C7 absorption circuit in series at the two ends of this series arm, one end that positive pole and the magnetic of diode D1 amplify coil L1 connects, and the negative pole of diode D1 connects with one end of electric capacity C7; Resistance R1 is parallel with at the two ends of electric capacity C7.
Cancerous protuberance block proportion due to cancerization is obviously increased to Normocellular 2-4 doubly, and therefore the resonant frequency of its body also can increase according to a specific curve accordingly.The present invention applies the identical pulsating field bundle of body self resonant frequency of a frequency and cancerous protuberance block to cancerous protuberance block according to this feature, for its magnetic force bundle must be enlarged into a thin superfine magnetic force bundle as acupuncture needle magnetic field bundle through magnetic amplifier by the misery reducing patient in therapeutic process; Now in the mode of matrix-scanning, treatment is implemented to lesions position again.Because the body of cancerous protuberance block is different, not of uniform size, and different parts, different types of cancerous protuberance block are also not quite similar, and therefore require that the frequency of this magnetic force bundle must random probing and auto modification.As everyone knows, the destructive power of resonance is very large, therefore makes cancerous protuberance block produce high temperature from inside to outside by the destruction of magnetic force resonance, thus kills cancerous cell.
Because the selectivity of resonant interaction is very strong, therefore the injury of normal tissue can be accomplished minimum.The problem how composition after being destroyed as cancerous cell processes, because its main component is still aminoacid (it is elementary composition is still carbon, nitrogen, hydrogen, oxygen, phosphorus etc.), wherein phosphorus is the typochemical element of biological DNA, because measure DNA gene according to measuring with the content of phosphorus, the nutritional labeling that finally these basic elements still can be used as human body is absorbed and used.
About cancerous protuberance block body tissue to the sensitivity in magnetic field: according to utilizing magnetic field to the conclusion (of pressure testing) of animal body in medical physics study course, the injury of high frequency magnetic field to animal body is larger, and the magnetic field of 1-20Hz is useful to animal body only, and the own resonance frequency of each internal organs of human body is also between 1-20Hz, this is also for magnetic resonance treatment provides foundation.And in various material, substantially can be divided into ferromagnetics, inverse magnetic substance and paramagnetics three class material, and as: itching as paramagnetics in aminoacid, and nitrogen and water are inverse magnetic substance, carbon is then ferromagnetics.But no matter which kind of material is amplified to a certain degree being applied to the field intensity on it, the atomic nucleus of its inside tumor and the characteristics of motion of electronics rotated around core and energy level all can change, and the larger molecular changes of density is more obvious, generate heat also can be more simultaneously, karyon due to malignant cell obviously increases to Normocellular 2-4 doubly, obvious proportion also can increase according to certain ratio, and therefore under the effect of strong magnetic force bundle, first cancerous protuberance block can be heated to more than 70 DEG C and thoroughly be killed.
The exportable frequency of medium frequency control circuit of the present invention gradually changes from 1 ~ 100Hz (can from low to High variation, also can from high to low change) pulse signal, this pulse signal acts on magnetic amplifier and makes main coil produce the magnetic force bundle of superfine (thin as acupuncture needle), makes this magnetic force bundle vertical sand shooting to the cancerous protuberance block in patient body, when the frequency of this magnetic force bundle is different with body self resonant frequency of cancerous protuberance block, cancerous protuberance block can not form resonance and can not generate heat, the change of the pulse signal frequency exported along with frequency control circuit, always there is a Frequency point identical with body self resonant frequency of cancerous protuberance block, when the frequency of magnetic force bundle is identical with body self resonant frequency of cancerous protuberance block, the frequency of now pulse signal just can be locked by frequency control circuit, and the magnetic force bundle continuous action (action time can set) that locking frequency is corresponding is thus in cancerous protuberance block place, cancerous protuberance block is made to produce resonance, while resonance, cancerous protuberance block produces high temperature and causes flatulence of heat type pain, cancerous protuberance block can be rapidly heated to more than 70 DEG C, thus kill cancerous cell.The frequency of the pulse signal adopted in the present invention is 1 ~ 100Hz, although the own resonance frequency of each internal organs of human body is between 1-20Hz, the frequency of 20 ~ 100Hz also can not cause too large harm to human body.
Can high temperature be produced due to cancerous protuberance block when resonating and cause flatulence of heat type pain, beat pulse generally can be forced to accelerate, pressure cell and pulse acceleration detection circuit is devised based on this in the present invention, the pressure of patient pulse is detected by pressure cell, and judge whether pulse accelerates according to the signal that pressure cell transmits, when pulse accelerates for frequency control circuit provides the triggering signal of locking frequency by pulse acceleration detection circuit.
But, when pressure cell is insensitive to indivedual crowd, cancerous protuberance block small volume, resonant frequency are higher or when not producing resonance, also by Hall element and magnetic field amplification detection circuit for frequency control circuit provides the triggering signal of locking frequency, the pressure cell of itself and the former and pulse accelerate detection circuit can combined effect, when both one of have an output signal time, namely lock pulse signal frequency now by frequency control circuit.The cancerous cell molecular weight of, different organs less for cancerous protuberance block or resonant frequency higher time, also by manually regulating magnetic field (magnetic force bundle) frequency by force, the scope easily extensible of manual adjustments frequency is to 150Hz.Be provided with frequency raise button AN2 and frequency in the present invention and reduce button AN3, frequency reduce button AN3 and frequency raise button AN2 with the use of can realize pulse signal frequency increasing, subtract meticulous adjustment.
Single-chip microcomputer IC2 in frequency control circuit receives the level signal that pulse accelerates detection circuit and the output of magnetic field amplification detection circuit, go back the operation signal of receive frequency raise button AN2 and frequency reduction button AN3 simultaneously, the signal of single-chip microcomputer IC2 received by it, control its frequency conversion outfan and carry frequency conversion instruction (making the frequency of pulsed magnetic field increase or reduce) to IC1A on time base apparatus, time base apparatus, IC1A was after receiving the instruction exported by the frequency conversion outfan of single-chip microcomputer IC2, pulse-width adjustment is carried out to the pulse signal that it exports, be that positive and negative pulsewidth is synchronously carried out during adjustment, to guarantee that dutycycle is constant.The pulse signal that time base apparatus, IC1A exported carries out amplifying and promotes to be wound on the main coil generation pulsed magnetic field on open core, amplify coil pulse magnetic field Shu Jinhang boundling through another synchronous magnetic again to amplify, to make, magnetic force bundle becomes thinner, magnetic force is more concentrated, obviously can alleviate the misery of patient over the course for the treatment of.
The present invention's magnetic force bundle acts on cancerous protuberance block and wants flexibly a lot of to the Therapeutic Method killing cancerous cell relative to excision to make it form resonant heating, utilize the stronger selectivity of tumor body magnetic force resonance can carry out independent scanning and treatment to blood supply passage, substantially can remove the possibility of recurrence from.
Accompanying drawing explanation
Fig. 1 is circuit structure block diagram of the present invention.
Fig. 2 is the electrical block diagram that pulse accelerates detection circuit.
Fig. 3 is the electrical block diagram of magnetic field amplification detection circuit.
Fig. 4 is the electrical block diagram of frequency control circuit.
Fig. 5 is operational flowchart of the present invention.
Detailed description of the invention
As shown in Figure 1, treatment of cancer device provided by the present invention comprises magnetic amplifier, Hall element, magnetic field amplification detection circuit, pressure cell, pulse acceleration detection circuit, frequency control circuit and power supply.
Power supply connects with the alternating current power supply of 220V, and it provides required running voltage for accelerating detection circuit, magnetic field amplification detection circuit and magnetic amplifier to frequency control circuit, pulse.Power supply exports the DC voltage-stabilizing of 24V, and the DC voltage-stabilizing of this 24V is directly supplied to magnetic amplifier; The DC voltage-stabilizing of 24V exports the DC voltage-stabilizing of 12V after the manostat of 12V, and the DC voltage-stabilizing of 12V is supplied to pulse and accelerates detection circuit and magnetic field amplification detection circuit, is also supplied to the pulse-width modulation circuit in frequency control circuit simultaneously.
Frequency control circuit comprises data processing circuit and pulse-width modulation circuit, as shown in Figure 4, the control core of data processing circuit is single-chip microcomputer IC2(AT89S2051), the core devices of pulse-width modulation circuit has IC1A(NE555 on time base apparatus), adjustable voltage stabilizer IC3(LM317), optocoupler GO1(PC817), optocoupler GO2(PC817), audion Q1(8050), diode D2(IN4148) and diode D3(IN4148) etc.Running voltage needed for data processing circuit in frequency control circuit is 5V, therefore, the 12V DC voltage-stabilizing exported by the manostat of 12V again after the manostat of 5V for data processing circuit provides the direct-current working volts of 5V.
Pressure cell and pulse accelerate detection circuit and connect, and pressure cell is generally placed in the wrist place of patient, can be fixed and be installed on wrist strap, then wrist strap is applied to wrist place; Pressure cell for receiving the pressure signal of patient pulse, and received pressure signal is converted into the signal of telecommunication export to pulse accelerate detection circuit.Pulse accelerates detection circuit according to the signal of telecommunication transmitted by pressure cell received, and judges whether the pulse of patient accelerates, and exports pulse signal for faster (this signal is a level signal in fact) when the pulse of patient accelerates to frequency control circuit.
Hall element connects with magnetic field amplification detection circuit, Hall element is generally arranged on body surface place corresponding to cancerous protuberance block in patient body, it is for receiving the field signal at cancerous protuberance block place in patient body, and received field signal is converted into the signal of telecommunication and exports to magnetic field amplification detection circuit.Magnetic field amplification detection circuit is according to the signal of telecommunication transmitted by Hall element received, judge whether the field strength (or amplitude) at cancerous protuberance block place in patient body strengthens, and export magnetic field enhancing signal (this signal is a level signal in fact) to frequency control circuit when the field strength at cancerous protuberance block place strengthens in patient body.
Magnetic amplifier connects with frequency control circuit, magnetic amplifier comprises main coil and the magnetic amplification coil of series connection mutually, on the rectangle iron core that main coil can be wound on an opening or annular core (in C font structure), also can be wound on the iron core of U-shaped, that is: main coil be wound on one have opening not close iron core on, cancerous protuberance block in the corresponding patient body of the opening part of open core, should ensure during successive treatment that magnetic force bundle vertical sand shooting that main coil produces at open core opening part is to the cancerous protuberance block in patient body.For the iron core in C font structure, the magnetic pole formed in iron core opening part two ends is relative, and both are straight line, when acting on cancerous protuberance block, cancerous protuberance block can be made to be between two magnetic poles, make two magnetic poles be positioned at the both sides of cancerous protuberance block.For the iron core in U-shaped structure, the magnetic pole formed in iron core opening part two ends is parallel, when acting on cancerous protuberance block, can make one of them magnetic pole or two magnetic pole common vertical directive cancerous protuberance blocks.Magnetic amplifies coil winding on annular (being a such as annular) iron core closed, annular core is positioned at the opening part of main coil institute coiling iron core, and main coil passes perpendicularly through the center of annular core at the magnetic force bundle that the opening place of its coiling iron core produces, utilize the repulsion in same polarity magnetic field magnetic field lines bundle can be concentrated towards the center of circle, the using beam of magnetic line of force of such main coil will be compressed (amplification), becomes thinner more concentrated immediately.The magnetic line of force high concentration produced for making main coil also can adopt multistage magnetic to amplify, and the result done like this can make patient's misery over the course for the treatment of significantly weaken.
Data processing circuit in frequency control circuit accelerates detection circuit with pulse respectively and magnetic field amplification detection circuit connects, and pulse-width modulation circuit connects with magnetic amplifier.Data processing circuit sends frequency conversion instruction to pulse-width modulation circuit, pulse-width modulation circuit receive data processing circuit after the frequency conversion instruction sent out, adjust the pulsewidth of the pulse signal that will export, the frequency of the pulse signal exported after adjustment meets the requirement of the frequency conversion instruction that data processing circuit exports.Final by pulse-width modulation circuit output pulse signal to magnetic amplifier, make the main coil in magnetic amplifier produce magnetic field and restraint and act on the cancerous protuberance block in patient body.If the frequency (i.e. the frequency of pulse signal) of magnetic field bundle (or claiming magnetic force bundle) is different from the body resonant frequency of cancerous protuberance block self, then send frequency conversion instruction to pulse-width modulation circuit by data processing circuit, the frequency of the pulse signal exported to make pulse-width modulation circuit gradually changes, until the body resonant frequency of the frequency and cancerous protuberance block self of magnetic field bundle is identical, now by data processing circuit locking frequency, and control the pulse signal that pulse-width modulation circuit exports locking frequency, the pulse signal of this locking frequency drives magnetic amplifier, the magnetic field bundle that in magnetic amplifier, main coil produces acts on cancerous protuberance block place, cancerous protuberance block is made to form resonance, cancerous protuberance block produces high temperature when resonating makes it be warming up to more than 70 DEG C gradually, thus kill cancerous cell.
When judging that whether the body resonant frequency of the frequency and cancerous protuberance block self that the magnetic field that main coil produces is restrainted is identical, realize by pulse acceleration detection circuit or magnetic field amplification detection circuit.Can high temperature be produced due to cancerous protuberance block when resonating and cause flatulence of heat type pain, beat pulse generally can be forced to accelerate, therefore, if pulse accelerates detection circuit and pressure cell combined effect, the pulse detecting patient has acceleration, then illustrate that the body resonant frequency of the frequency and cancerous protuberance block self of now magnetic field bundle is identical, cancerous protuberance block is made to there occurs resonance, now accelerate detection circuit to the data processing circuit transmission level signal in frequency control circuit by pulse, to make data processing circuit locking frequency now.On the contrary, if pulse accelerates detection circuit and pressure cell does not detect pulse acceleration, then illustrate that the body resonant frequency of the frequency and cancerous protuberance block self of magnetic field bundle is different, pulse accelerates detection circuit not to data processing circuit transmission level signal.But, may be insensitive to pressure cell because of somebody group, or because of cancerous protuberance block small volume, the more high reason of resonant frequency and cause pulse accelerate detection circuit detection accelerate less than pulse, now wrong in order to avoid detecting, detect cancerous protuberance block by magnetic field amplification detection circuit and Hall element and whether reach resonance.When cancerous protuberance block resonates, its magnetic field intensity can strengthen, therefore, the position corresponding with cancerous protuberance block by the body surface patient arranges Hall element, the field signal of cancerous protuberance block in patient body is received by Hall element, received field signal is converted into the signal of telecommunication and exports to magnetic field amplification detection circuit by Hall element, judge whether the magnetic field of cancerous protuberance block strengthens by magnetic field amplification detection circuit according to the signal of telecommunication received, strengthen if judged result is magnetic field, then illustrate that the body resonant frequency of the frequency and cancerous protuberance block self of magnetic field bundle is identical, by magnetic field amplification detection circuit to the data processing circuit transmission level signal in frequency control circuit, to make data processing circuit locking frequency now.If judged result magnetic field does not strengthen, then illustrate that the body resonant frequency of the frequency and cancerous protuberance block self of magnetic field bundle is different, magnetic field amplification detection circuit is not to data processing circuit transmission level signal.Hall element, when arranging, can be located at the side of the iron core opening part of main coil coiling, that is: make Hall element depart from cancerous protuberance block place a little at the body surface of patient.This departing from a little, the magnetic field intensity of its detection cancerous protuberance block can not be affected.
If data processing circuit does not receive the level signal being accelerated detection circuit transmission by magnetic field amplification detection circuit or pulse, the then frequency conversion instruction (i.e. pulse-width signal) that constantly changes of output frequency, controls the pulse signal that pulse-width modulation circuit output frequency gradually changes from 1 ~ 100Hz; Data processing circuit is accelerated the level signal of detection circuit transmission by magnetic field amplification detection circuit or pulse once receive, then lock the frequency of now (pulse-width signal), and output order controls the pulse signal that pulse-width modulation circuit exports locking frequency, namely the pulse signal of this locking frequency is the pulse signal that self body resonant frequency of frequency and cancerous protuberance block is identical.The pulse-width signal that the frequency that data processing circuit exports constantly changes, makes it automatically to export by setting cycle by program, and it also can be made under artificial manual operation to export by manual operation instruction.Generally, making data processing circuit export 1 ~ 50Hz(by setting cycle by programming can from high to low, also can from low to high) pulse-width signal; For higher than 50Hz(such as 50 ~ 100Hz, or higher) pulse-width signal, by arranging frequency raise button and frequency reduces button, under manual operation, make data processing circuit output pulse width modulation signal on request.This is because, frequency is higher, the cycle is shorter, and follow procedure automatically exports and may occur omitting, and can not remedy in time when there is omission; And during manual operation, be provided with frequency raise button and frequency reduction button, once the frequency of pulse-width signal higher than locking frequency, reduce button by frequency in time the frequency of pulse-width signal to be reduced, to find the pulse-width signal of locking frequency fast.Frequency control circuit can rate of connections display, is shown in real time the frequency of pulse-width signal (that is pulse-width modulation circuit export frequency of pulse signal) by ondoscope.
Below the particular circuit configurations of pulse acceleration detection circuit, magnetic field amplification detection circuit and frequency control circuit is described in detail.
As shown in Figure 2, pressure cell accelerates detection circuit by single core socket and pulse and connects, and in the present embodiment, pressure cell is ceramic pressure element, pressure signal for receiving human body pulse pressure signal (i.e. pulse velocity variable signal), and can be converted into the signal of telecommunication by it.The outfan of pressure cell is connected to coupling capacitance C27(205 through the jack of single core socket) one end, simultaneously, the outfan of pressure cell is through the jack also contact resistance R54(220K of single core socket, 1K=1000 Ω) one end, the other end earth lead of resistance R54, by resistance R54 Absorbable rod noise signal, the other end of coupling capacitance C27 connects amplifier IC13(LM358) (amplifier, the i.e. abbreviation of operational amplifier, the abbreviation of power amplifier and power amplifier in the present invention) in-phase input end (i.e. 3 feet of amplifier IC13), the inverting input (2 foot) of amplifier IC13 is connected to resistance R9(10K) and resistance R10(10K) connected node, resistance R9 and resistance R10 connects, one end of resistance R9 connects the power supply of+12V, one terminate ground wire of resistance R10, the connected node of resistance R9 and resistance R10 connects with the inverting input of amplifier IC13, the inverting input of amplifier IC13 obtains static work voltage after resistance R9 and resistance R10 dividing potential drop.The positive terminal (8 foot) of amplifier IC13 connects the power supply of+12V, negative pole end (4 foot) earth lead of amplifier IC13.
After the in-phase input end of amplifier IC13 receives signal, namely forcing the outfan (1 foot) of amplifier IC13, output level from low to high, the outfan of amplifier IC13 is through resistance R23(1K) be connected to decade computer IC14(CC4017) the 14 foot inputs of (be called for short enumerator IC14), the 14 foot inputs of enumerator IC14 also connect pull down resistor R53(20K) one end, the other end earth lead of pull down resistor R53.Enumerator IC14 has ten outfans.The reset terminal (15 foot) of enumerator IC14 connects electrification reset electric capacity C33(105) one end, the other end of electrification reset electric capacity C33 connects the power supply of+12V; Electrification reset electric capacity C33 is for guaranteeing that the outfan initial value of enumerator IC14 is 0.The reset terminal of enumerator IC14 also connects pull down resistor R57(10K) one end, the other end earth lead of pull down resistor R57.
Pressure cell often detects beat pulse once, just detected pressure signal be converted into the signal of telecommunication and export the in-phase input end of amplifier IC13 through coupling capacitance C27 to, and then force the outfan of amplifier IC13 to export high level, this high level signal is sent to the 14 foot inputs of enumerator IC14, and one of them outfan of rear drive enumerator IC14 exports high level.In the present embodiment, when first pulse signal is after detecting, transform and transferring to the 14 foot inputs of enumerator IC14, first outfan (i.e. 2 feet) of enumerator IC14 exports high level.First outfan of enumerator IC14 connects adjustable voltage stabilizer IC5(LM317) input, adjustable voltage stabilizer IC5 here uses as constant current device.Adjustable voltage stabilizer IC5 outfan and adjustment hold between be connected to resistance R43(910), resistance R43 be adjustable voltage stabilizer IC5 export constant current value set resistance, its resistance is generally 1.25/I
h.Adjustable voltage stabilizer IC5 adjustment end export constant current, this constant current (i.e. the adjustment end of adjustable voltage stabilizer IC5) is connected to electrochemical capacitor C31(16V, 470) positive pole, the minus earth line of electrochemical capacitor C31.Adjustable voltage stabilizer IC5, resistance R43 and electrochemical capacitor C31 form the first constant-current charging circuit.Magnitude of voltage on electrochemical capacitor C31 represents the persistent period (i.e. signal period) of first pulse signal; When end of charging after next pulse signal arrival, electrochemical capacitor C31 has recorded the cycle of first pulse signal.
After second pulse signal arrives, second outfan (i.e. 4 feet) of enumerator IC14 exports high level.Second outfan of enumerator IC14 connects adjustable voltage stabilizer IC6(LM317) input, at the outfan of adjustable voltage stabilizer IC6 and the indirect resistance R44(910 of adjustment end), the adjustment termination electrochemical capacitor C32(16V of adjustable voltage stabilizer IC6,470) positive pole, the minus earth line of electrochemical capacitor C32.Similar to the first constant-current charging circuit, adjustable voltage stabilizer IC6, resistance R44 and electrochemical capacitor C32 form the second constant-current charging circuit.Magnitude of voltage on electrochemical capacitor C32 represents the persistent period (i.e. signal period) of second pulse signal.
The positive pole of electrochemical capacitor C31 is through resistance R51(47K) be connected to amplifier IC15(LM358) in-phase input end, the positive pole of electrochemical capacitor C32 is through resistance R50(47K) be connected to amplifier IC15(LM358) inverting input.Amplifier IC15 is a comparator in fact, because electrochemical capacitor C31 and electrochemical capacitor C32 have recorded the cycle of first pulse signal and second pulse signal respectively, therefore, all after dates that the in-phase input end of amplifier IC15 and reverse input end receive two pulse signals respectively compare the size in two cycles, if pulse is in acceleration, then the cycle (i.e. pulsewidth) of second pulse signal is less than the cycle of first pulse signal, the outfan of amplifier IC15 will export high level, otherwise the outfan of amplifier IC15 will output low level.The outfan of amplifier IC15 is through resistance R55(2.4K) be connected to optocoupler GO5(PC817) input anode of (i.e. photoelectrical coupler), the outfan of amplifier IC15 also connects electric capacity C30(105) one end, the other end earth lead of electric capacity C30.
After the 3rd pulse signal arrives, the 3rd outfan (i.e. 7 feet) of enumerator IC14 exports high level.3rd outfan of enumerator IC14 is through resistance R56(12K) be connected to audion Q7(8050) base stage, the grounded emitter line of audion Q7, the colelctor electrode of audion Q7 is connected to the input cathode of optocoupler GO5.When the 3rd outfan of enumerator IC14 exports high level, this high level signal through resistance R56 for audion Q7 provides base current, force audion Q7 conducting, colelctor electrode due to audion Q7 connects the input cathode of optocoupler GO5, therefore the input cathode of optocoupler GO5 can be connected to ground wire after audion Q7 conducting; Now, if there is pulse to accelerate, then amplifier IC15 exports high level, a pulldown signal will be produced at the output head anode of optocoupler GO5, the output head anode of optocoupler GO5 is connected to the input (P3.1 foot) of single-chip microcomputer IC2 in frequency control circuit (see Fig. 4, P3.1 foot is the frequency lock signal input part of single-chip microcomputer IC2), the negative pole of output end earth lead of optocoupler GO5.
After the 4th pulse signal arrives, the 4th outfan (i.e. 10 feet) of enumerator IC14 exports high level.4th outfan of enumerator IC14 is through resistance R40(24K) be connected to audion Q5(8050) base stage, simultaneously, 4th outfan of enumerator IC14 is also through resistance R39(24K) be connected to audion Q6(8050) base stage, the equal earth lead of emitter stage of audion Q5 and audion Q6; The colelctor electrode of audion Q5 is through discharge resistance R47(470) connect the positive pole of electrochemical capacitor C31, the colelctor electrode of audion Q6 is through discharge resistance R46(470) connect the positive pole of electrochemical capacitor C32.When the 4th outfan of enumerator IC14 exports high level, this high level signal provides base current to respectively audion Q5 and audion Q6 through resistance R40 and resistance R39, and force audion Q5 and audion Q6 conducting, respectively electrochemical capacitor C31 and electrochemical capacitor C32 is discharged, in order to the periodic duty of follow-up pulse signal through discharge resistance R47 and discharge resistance R46 again.
After the 5th pulse signal arrives, the 5th outfan (i.e. 1 foot) of enumerator IC14 exports high level.5th outfan of enumerator IC14 is through diode D10(IN4148) reset terminal (15 foot) of linkage counter IC14, and the positive pole of diode D10 connects with the 5th outfan (i.e. 1 foot) of enumerator IC14.When the 5th outfan of enumerator IC14 exports high level, this high level signal is sent to the reset terminal of enumerator IC14 after diode D10, forces enumerator IC14 to reset, and restarts the loop detection of next round.
It should be noted that, in the loop detection process that each is taken turns, although only compare the cycle of first pulse signal and second pulse signal, but, due to can not be simple when pulse accelerates only beat twice, but the persistent period is longer, even if so only compare the cycle of two pulse signals in each loop detection process of taking turns, also there will not be undetected, result of detection is also more accurately.
But, when part population is insensitive to pressure cell, or because of cancerous protuberance block small volume, the more high reason of resonant frequency and cause pulse accelerate detection circuit detection accelerate less than pulse time, whether the magnetic field intensity detecting cancerous protuberance block place by magnetic field amplification detection circuit and Hall element increases.
As shown in Figure 3,1 foot (power end) of Hall element H1A connects the power supply of+12V, its 3 foot (earth terminal) earth lead, its 2 foot (signal end, or claim outfan) through coupling capacitance C25(205) connect low-frequency power amplifier IC11(LM386) in-phase input end (3 foot), the 2 feet also contact resistance R49(47K of Hall element) one end, the other end earth lead of resistance R49, by resistance R49 Absorbable rod noise signal.Hall element is a kind of magnetic-sensitive elements, and it can detect the field intensity change of Weak magentic-field, and field signal is converted into voltage signal.In the present invention, Hall element H1A, usually can with the enhancing of amplitude when magnetic field (magnetic force bundle) occurs to resonate with body carcinoma soma in order to the power in direct impulse magnetic field.
6 feet of power discharging IC 11 are power end, and power end connects the power supply of+12V, and its 4 foot is earth terminal, and 4 feet connect ground wire, and meanwhile, the inverting input of 2 feet also connects ground wire.The outfan (5 foot) of power discharging IC 11 is through resistance R48(15K) connect electric capacity C26(205) one end, the other end earth lead of electric capacity C26.Resistance R48 and electric capacity C26 forms the 3rd charge circuit.The connected node of resistance R48 and electric capacity C26 is through resistance R22(1K) with amplifier IC16(LM358) in-phase input end (3 foot) connect, the in-phase input end also contact resistance R52(20K of amplifier IC16) one end, the other end earth lead of resistance R52.The inverting input (2 foot) of amplifier IC16 connects by manostat IC4(LM317), resistance R45(470) and resistance R41(910) the quiescent potential regulating circuit that forms.The input of manostat IC4 connects the power supply of+12V, and resistance R45 is connected between the outfan of manostat IC4 and adjustment hold, one end of the adjustment end contact resistance R41 of manostat IC4, the other end earth lead of resistance R41; The connected node (i.e. the adjustment end of manostat IC4) of resistance R45 and resistance R41 connects with the inverting input of amplifier IC16, and the inverting input of amplifier IC16 also connects electric capacity C29(104) one end, the other end earth lead of electric capacity C29.Manostat IC4 is adjustable voltage stabilizer, produces a burning voltage, as the quiescent potential of amplifier IC16 inverting input between resistance R45 and resistance R41; Change any one resistance in resistance R45 and resistance R41 and all can change quiescent potential, to adapt to the sensitivity of Hall element H1A.
The positive terminal (8 foot) of amplifier IC16 connects the power supply of+12V, its negative pole end (4 foot) earth lead.The outfan (1 foot) of amplifier IC16 is through resistance 42(910) with optocoupler GO4(PC817) input anode connect, in the output head anode of optocoupler GO4 and frequency control circuit, the input P3.2 foot of single-chip microcomputer IC2 is (see Fig. 4, P3.2 foot is also the frequency lock signal input part of single-chip microcomputer IC2) connect, the input cathode of optocoupler GO4 and the equal earth lead of its negative pole of output end.The outfan of amplifier IC16 also connects electric capacity C28(104) one end, the other end earth lead of electric capacity C28.
Hall element H1A receives the field signal of change and is converted into voltage signal, voltage signal is coupled to the in-phase input end of power discharging IC 11 through coupling capacitance C25, after power discharging IC 11 amplifies, produce amplitude at its outfan be 0-Vcc(Vcc is 12V) alternating voltage signal, this voltage signal charges to electric capacity C26 through resistance R48, and electric capacity C26 voltage progressively raises; If this charging process time long enough (charging interval depends on frequency and the cycle of pulsed magnetic field, and the frequency lower cycle is longer), the voltage at electric capacity C26 two ends just raises, and is connected to the in-phase input end of amplifier IC16 through resistance R22; If now the voltage of the in-phase input end of amplifier IC16 is higher than the quiescent potential set by its inverting input, so the outfan of amplifier IC16 will export high level, and make optocoupler GO4 conducting and output signal, the output head anode of optocoupler GO4 is connected to the P3.2 foot of single-chip microcomputer IC2, for single-chip microcomputer IC2 provides judgment signal.
Diode D9(IN4007 is parallel with between the two ends of resistance R48), the positive pole of diode D9 connects with the connected node of resistance R48 and electric capacity C26, and the negative pole of diode D9 connects the outfan of power discharging IC 11.Resistance R48 provides the charging voltage of electric capacity C26, and diode D9 provides discharge channel for high-frequency signal; Every all higher than setpoint frequency signal because of its cycle shorter, just finish when electric capacity C26 both end voltage does not also reach the trigger voltage of rear class, and power discharging IC 11 output end voltage will be dragged down and discharge into zero through diode D9; Therefore this circuit has absolute inhibitory action to the various High-frequency Interference in outside, spatial electromagnetic interference, prevents entering of all interfering signals.
As shown in Figure 4, frequency control circuit comprises data processing circuit and pulse-width modulation circuit, the control core of data processing circuit is single-chip microcomputer IC2, the power end of single-chip microcomputer IC2 connects the power supply of+5V, electrochemical capacitor C10(22U) positive pole connect the power supply of+5V, the negative pole of electrochemical capacitor C10 connects the reset terminal (RST foot) of single-chip microcomputer IC2, and the negative pole of electrochemical capacitor C10 is also through resistance R11(1K) earth lead; Electrochemical capacitor C10 and resistance R11 forms the automatic reset system of single-chip microcomputer IC2.Electric capacity C8(30P) one end connect the input X2 foot of single-chip microcomputer IC2, its other end earth lead; Electric capacity C9(30P) one end connect the input X1 foot of single-chip microcomputer IC2, its other end earth lead; Crystal oscillator JZ1(4MC is connected between the input X2 foot and X1 foot of single-chip microcomputer IC2), crystal oscillator JZ1 and electric capacity C8, C9 form the hunting of frequency system of single-chip microcomputer IC2.Input P3.0 foot and the common composition function start-up circuit of press button AN1 be attached thereto of single-chip microcomputer IC2; The input P3.1 foot of single-chip microcomputer IC2 connects the output head anode of optocoupler GO5, and it accelerates the pulse signal for faster of detection circuit output in order to receive pulse; The input P3.2 foot of single-chip microcomputer IC2 connects the output head anode of optocoupler GO4, its magnetic field enhancing signal exported in order to receive magnetic field amplification detection circuit; The input P3.4 foot of single-chip microcomputer IC2 and the frequency raise button AN2 be attached thereto form manual frequency jointly increases functional switch; The frequency reduction button AN3 that the input P3.5 foot of single-chip microcomputer IC2 is attached thereto forms manual frequency reduction functional switch jointly.
The pulse-width signal that the frequency conversion outfan (P3.7 foot) of single-chip microcomputer IC2 gradually changes from 1 ~ 100Hz for output frequency.When pressing the button switch AN1, single-chip microcomputer IC2 startup optimization program, first the amplification step-length of setting data treatment circuit is that each detect cycle frequency adds 1(hertz), arrange frequency conversion direction (1-50Hz) from low to high, now display lamp LED1(is green) light.Single-chip microcomputer IC2 detect time, can detect simultaneously optocoupler GO5(namely detect pulse accelerate detection circuit have the output of pulseless signal for faster) and optocoupler GO4(namely detect the output of magnetic field amplification detection circuit with or without magnetic field enhancing signal) have non-output signal; Also first can detect optocoupler GO5 and have non-output signal, when optocoupler GO5 non-output signal, then detect optocoupler GO4 and have non-output signal.In the present embodiment, first loop detection pulse accelerates detection circuit has pulseless signal for faster to export, and the frequency of output pulse width modulation signal is progressively increased to 50Hz by 1Hz simultaneously; If now still do not have pulse signal for faster to export, then arrange frequency change direction for " from high to low ", control display lamp LED1 simultaneously and extinguish, display lamp LED2(is yellow) light; Recirculation differentiates that cancerous protuberance block place (i.e. face, focus territory) magnetic field increases (namely differentiating that optocoupler GO4 has no-output) with or without field intensity, if do not increased, then exports resonance free prompting, controls display lamp LED3(red) light.Now manual operation (frequency raise button AN2 or frequency reduce button AN3) can increase or reduce frequency (change by ondoscope observed frequency), frequency range can adjust between 1-100Hz, and this operation is especially suitable for the situation that lump is less, resonant frequency is higher.The positive pole of display lamp LED1, LED2, LED3 all connects the power supply of+5V, and the negative pole of three display lamps connects respectively by the outfan pin that corresponding resistance is different from three of single-chip microcomputer IC2.
In the process of the pulse-width signal gradually changed through procedure auto-control or the manual frequency conversion outfan output frequency adjusting single-chip microcomputer IC2, if when single-chip microcomputer IC2 receives the signal exported by optocoupler GO4 or optocoupler GO5 (when cancerous protuberance block produces and resonates), the program of single-chip microcomputer IC2 can automatic setpoint frequency variable be zero, and locking frequency; Set the same lesions position upper limit of continuous treatment time is 10min or other higher limit simultaneously.
In the present invention, the power supply of+24V is provided by power supply (see figure 1), and the power supply of+24V is directly supplied to magnetic amplifier; The power supply of+24V is through manostat IC7(7812) for IC1A on time base apparatus provides the power supply of+12V, namely the outfan (OUT) of manostat IC7 is the power end of+12V, the outfan of manostat IC7 provides the power supply of+12V to circuit in Fig. 2 and Fig. 3 simultaneously.The outfan of manostat IC7 connects manostat IC8(7805) input (IN), the outfan (OUT) of manostat IC8 provides the power supply of+5V for single-chip microcomputer IC2.The input (IN) of manostat IC7 connects electrochemical capacitor C11(35V, 1000) positive pole, the minus earth line of electrochemical capacitor C11; The outfan (being also the input of manostat IC8) of manostat IC7 connects electrochemical capacitor C2(16V, 470) positive pole, the minus earth line of electrochemical capacitor C2.The outfan of manostat IC8 connects electrochemical capacitor C3(16V, 470) positive pole, the minus earth line of electrochemical capacitor C3.Electric capacity C12(104 is also parallel with) at the two ends of electrochemical capacitor C3.Electric capacity C2, C3, C11, C12 are filter capacitor.
The core devices of pulse-width modulation circuit has IC1A on time base apparatus, adjustable voltage stabilizer IC3, optocoupler GO1, optocoupler GO2, audion Q1, diode D2 and diode D3 etc.Frequency conversion outfan and the resistance R19(1K of single-chip microcomputer IC2) and resistance R18(2K) connected node connect.Resistance R19 connects with resistance R18, one end of resistance R19 connects the power supply of+5V, the other end connects with resistance R18, resistance R18 one end connects with resistance R19, other end connecting triode Q1(8050) base stage, the grounded emitter line of audion Q1, namely single-chip microcomputer IC2 frequency conversion outfan export pulse-width signal (turnable pulse width, high level is effective) through resistance R19 and R18 for audion Q1 provides base current, and force its conducting.The colelctor electrode of audion Q1 connects by resistance R17(2K), resistance R14(3K), manostat IC3(LM317) and resistance R16(240) constant-current source circuit that forms.Specifically, one end of the colelctor electrode contact resistance R17 of audion Q1, the other end of resistance R17 connects with the adjustment end of manostat IC3 through resistance R14, and the input of manostat IC3 connects the power supply of+12V, and resistance R16 is arranged between the outfan of manostat IC3 and adjustment hold.Size of current in constant-current source circuit is decided by resistance R16.
Electrochemical capacitor C1(16V is parallel with at the two ends of resistance R14,470), the positive pole of electrochemical capacitor C1 connects the adjustment end of manostat IC3, the connected node of its negative pole contact resistance R14 and resistance R17, a voltage can be produced at positive and negative the two poles of the earth of electrochemical capacitor C1 by resistance R14, this voltage can be the optocoupler GO1(PC817 of two forward series connection) and optocoupler GO2(PC817) power supply (because two optocouplers are series connection, therefore the supply current moment is identical).Specifically, the positive pole of electrochemical capacitor C1 connects with the input anode of optocoupler GO2, and the input cathode of optocoupler GO2 connects with the input anode of optocoupler GO1, and the input cathode of optocoupler GO1 connects with the negative pole of electrochemical capacitor C1.The output head anode contact resistance R4(3K successively of optocoupler GO2), diode D3(IN4148) and oscillating capacitance C6(tantalum 16V, 10), the minus earth line of oscillating capacitance C6, the positive pole of oscillating capacitance C6 connects with the positive pole of diode D3, and the negative pole of output end of optocoupler GO2 connects with the discharge end (7 foot) of IC1A on time base apparatus; An adjustable auxiliary discharge loop is defined between the output head anode and its negative pole of output end of optocoupler GO2.The output head anode of optocoupler GO1 is through resistance R3(3K) with time base apparatus IC1A discharge end connect, negative pole of output end and the diode D2(IN4148 of optocoupler GO1) positive pole connect, the negative pole of diode D2 connects with the positive pole of oscillating capacitance C6.Negative pole due to diode D2 is connected to the positive pole of oscillating capacitance C6, therefore charges to oscillating capacitance C6 only and can not discharge to it, therefore between the output head anode and its negative pole of output end of optocoupler GO1, defines an adjustable auxiliary charging loop.
Time base apparatus, the power end (8 foot) of IC1A connected the power supply of+12V, time base apparatus IC1A the resistance R6(1K of power end also through connecting successively) and resistance R2(75K) after connect with the positive pole of oscillating capacitance C6, the connected node of resistance R6 and resistance R2 connects with the discharge end of IC1A on time base apparatus; Time base apparatus IC1A high level trigger end (6 foot) and low level trigger end (2 foot) all connect with the positive pole of oscillating capacitance C6; Time base apparatus IC1A earth terminal (1 foot) earth lead, time base apparatus, the reset terminal (4 foot) of IC1A connected the power supply of+12V, time base apparatus IC1A voltage controling end (5 foot) through electric capacity C5(0.1) earth lead, to prevent from introducing interference.Time base apparatus IC1A, resistance R6, resistance R2 and oscillating capacitance C6 form a self-oscillating circuit: self-oscillating circuit obtain electric after, because oscillating capacitance C6 both end voltage can not be suddenlyd change, initial value is lower than the threshold voltage Vcc(12V of IC1A on time base apparatus), thus time base apparatus IC1A outfan (3 foot) be high level; When oscillating capacitance C6(and time base apparatus IC1A 2,6 feet) voltage higher than " upper threshold values " voltage (i.e. 2/3Vcc) time, IC1A outfan on time base apparatus (3 foot) is low level, and discharge end (7 foot) discharges to oscillating capacitance C6 through resistance R2 and adjustable auxiliary discharge loop simultaneously; When oscillating capacitance C6(and time base apparatus IC1A 2,6 feet) voltage lower than " lower threshold values " voltage (i.e. 1/3Vcc) time, time base apparatus, the outfan of IC1A returned high level again, its discharge end (7 foot) open circuit simultaneously, the power supply of+12V charges to vibration C6 through resistance R6, resistance R2 and adjustable auxiliary charging loop.Can find out that the value of resistance R2 and oscillating capacitance C6 determines initial cycle of oscillation thus, and this initial value is set to 1Hz, the cycle is 1000ms, and unidirectional pulsewidth is 500ms.The turnable pulse width exported by single-chip microcomputer IC2 can be symmetrical adjusted to 100Hz, the namely each 5ms of positive and negative.
Time base apparatus IC1A outfan through resistance R5(1K) after respectively with audion Q3(8050) and audion Q4(8050) base stage connect, the grounded collector line of audion Q3, the colelctor electrode of audion Q4 connects with the power end of IC1A on time base apparatus, time base apparatus IC1A power end also through electric capacity C4(0.1) earth lead, with prevent interference; The emitter stage of audion Q3 and the emitter stage of audion Q4 connect.When time base apparatus, the outfan of IC1A exports as timing, and audion Q4 conducting, audion Q3 ends.Through resistance R7(51 after audion Q3 is connected with the emitter stage of audion Q4) with field effect transistor Q2(75NF75) grid connect, the grid of field effect transistor Q2 is also through resistance R8(10K) earth lead, the direct earth lead of source electrode of field effect transistor Q2, the magnetic that the drain electrode of field effect transistor Q2 connects in magnetic amplifier successively amplifies coil L1 and main coil L2.Signal exports through the emitter stage of audion Q3 and audion Q4, directly trigger field effect transistor Q2 through resistance R7, make the main coil L2(of series connection with it after field effect transistor Q2 conducting or claim inductance L 2) and magnetic amplify coil L1(or title inductance L 1) all electric and produce induced electromotive force and magnetic field.
Main coil L2 and magnetic amplify coil L1 and form series arm, the two ends of amplifying coil L1 and main coil L2 series arm at magnetic are connected with by diode D1(6A, 10) and electric capacity C7(250V, 105) absorption circuit formed, one end that positive pole and the magnetic of diode D1 amplify coil L1 connects, the negative pole of diode D1 connects with one end of electric capacity C7, and the other end of electric capacity C7 connects with one end of main coil L2, and one end of main coil L2 connects the power supply of+24V.Resistance R1(2W, 10K is parallel with) at the two ends of electric capacity C7.
Main coil L2 is wound on the iron core of opening, the lesions position both sides of the corresponding human body of iron core opening part or white mouse, and the parallel corresponding lesions position of two magnetic poles that also iron core opening part can be produced applies treatment.Because two inductance (i.e. two coils) are forward connected, therefore produced electromotive force and polarity of the magnetic field are all identical, magnetic being amplified coil L1 is wound on annular core, and make the magnetic line of force of main coil L2 through this annular core, utilize the repulsion in same polarity magnetic field large magnetic field lines bundle can be concentrated towards the center of circle, the using beam of magnetic line of force of such main coil L2 will be compressed (amplification), become thinner more concentrated immediately, for making magnetic line of force high concentration that multistage magnetic also can be adopted to amplify, the result done like this can make patient's misery over the course for the treatment of significantly weaken.
As shown in Figure 5, the concrete steps of Therapeutic cancer of the present invention are adopted to be: to start, the initial value of single-chip microcomputer IC2 is set, judge whether press button AN1 presses, if not, then reset initial value, if press button AN1 presses, frequency changer circuit (i.e. data processing circuit is then set, or single-chip microcomputer IC2) amplification step-length, frequency conversion direction is then set from low to high, judges that pulse is with or without acceleration subsequently, if pulse has acceleration, then arranging frequency variable is zero, locking frequency, arranges focus unit area continuous operation 10min, to kill cancerous cell, treatment terminates; If pulse does not accelerate, then frequency conversion direction is set from high to low, judges whether magnetic field amplitude increases; If increase signal without magnetic field amplitude, then export resonance free prompting, manually improve frequency, continue to judge whether magnetic field amplitude increases; If magnetic field amplitude increases, then arranging frequency variable is zero, locking frequency, arranges focus unit area continuous operation 10min, and to kill cancerous cell, treatment terminates.
It should be noted that, the components and parts such as the single-chip microcomputer mentioned in the embodiment of the present invention, amplifier, resistance, electric capacity, diode, audion, what indicate in bracket thereafter is the model of its correspondence, resistance, power or voltage etc., what indicate in bracket is only an object lesson, can also be replaced by the components and parts of other different models, different resistance or different capacity etc.
Claims (6)
1. a treatment of cancer device, is characterized in that, comprising:
Magnetic amplifier, connects with frequency control circuit, for generation of magnetic field, to act on the cancerous protuberance block in patient body from the body surface of patient;
Hall element, connects with magnetic field amplification detection circuit, for being arranged on body surface place corresponding to cancerous protuberance block in patient body, and the field signal at cancerous protuberance block place during to detect treatment, and detection signal is converted into the signal of telecommunication and exports to magnetic field amplification detection circuit;
Magnetic field amplification detection circuit, connects with described Hall element and frequency control circuit respectively, after the situation that magnetic field strengthens appears in cancerous protuberance block place in patient body, exports magnetic field enhancing signal to frequency control circuit;
Pressure cell, accelerates detection circuit with pulse and connects, for detecting pulse during patient treatment, and detection signal is converted into the signal of telecommunication export to pulse accelerate detection circuit;
Pulse accelerates detection circuit, connects respectively with described pressure cell and frequency control circuit, after there is acceleration situation patient pulse, exports pulse signal for faster to frequency control circuit;
Frequency control circuit, accelerate detection circuit with described magnetic amplifier, described magnetic field amplification detection circuit and described pulse respectively to connect, for to magnetic amplifier output frequency being the gradual change pulse signal of 1 ~ 100Hz, magnetic amplifier is made to produce the magnetic field for the treatment of, and when receiving pulse signal for faster or magnetic field enhancing signal, lock the pulse signal frequency this moment exported, continue to described magnetic amplifier the pulse signal exporting locking frequency; And
Power supply, accelerates detection circuit, described magnetic field amplification detection circuit and described magnetic amplifier for giving described frequency control circuit, described pulse and provides required running voltage.
2. treatment of cancer device according to claim 1, it is characterized in that, described magnetic amplifier comprises main coil and the magnetic amplification coil of series connection mutually, described magnetic amplifies coil winding on an annular core, described main coil is wound on an open core, and described main coil passes perpendicularly through the center of described annular core at the magnetic line of force that the opening place of described open core produces.
3. treatment of cancer device according to claim 1, it is characterized in that, the circuit structure that described pulse accelerates detection circuit is: the in-phase input end of amplifier IC13 connects with described pressure cell through electric capacity C27, the 14th foot input of the outfan linkage counter IC14 of amplifier IC13; The 2nd foot outfan of enumerator IC14 connects the first charge circuit be made up of manostat IC5, resistance R43 and electrochemical capacitor C31, and the outfan of the first charge circuit connects the in-phase input end of amplifier IC15 through resistance R51; The 4th foot outfan of enumerator IC14 connects the second charge circuit be made up of manostat IC6, resistance R44 and electrochemical capacitor C32, the outfan of the second charge circuit connects the inverting input of amplifier IC15 through resistance R50, the outfan of amplifier IC15 connects the input anode of optocoupler GO5; The 7th foot outfan of enumerator IC14 connects the base stage of audion Q7 through resistance R56, the colelctor electrode of audion Q7 connects the input cathode of optocoupler GO5, and the output head anode of optocoupler GO5 connects with described frequency control circuit; The 10th foot outfan of enumerator IC14 divides two-way, one tunnel connects with the base stage of audion Q5 through resistance R40, another road connects with the base stage of audion Q6 through resistance R39, the colelctor electrode of audion Q5 connects the outfan of the first charge circuit through electricity group R47, the colelctor electrode of audion Q6 connects the outfan of the second charge circuit through electricity group R46; The 1st foot outfan of enumerator IC14 connects the 15th pin preset end of enumerator IC14 through diode D10, the 15th pin preset end of enumerator IC14 is connected to electrification reset electric capacity C33.
4. treatment of cancer device according to claim 1, it is characterized in that, the circuit structure of described magnetic field amplification detection circuit is: the in-phase input end of power discharging IC 11 connects the 2 foot outfans of Hall element H1A through electric capacity C25, the outfan of power discharging IC 11 connects the 3rd charge circuit be made up of resistance R48 and electric capacity C26, diode D9 is parallel with between the two ends of resistance R48, the resistance R48 of the 3rd charge circuit and the connected node of electric capacity C26 connect the in-phase input end of amplifier IC16 through resistance R22, the inverting input of amplifier IC16 connects by manostat IC4, the quiescent potential regulating circuit that resistance R45 and resistance R41 forms, the outfan of amplifier IC16 connects with the input anode of optocoupler GO4 through resistance R42, and the output head anode of optocoupler GO4 connects with described frequency control circuit.
5. treatment of cancer device according to claim 1, it is characterized in that, the circuit structure of described frequency control circuit is: the frequency conversion outfan of single-chip microcomputer IC2 connects the base stage of audion Q1 through resistance R18, the grounded emitter line of audion Q1, the colelctor electrode of audion Q1 connects the constant-current source circuit be made up of resistance R17, resistance R14, manostat IC3 and resistance R16; Electrochemical capacitor C1 is parallel with at the two ends of resistance R14, the positive pole of electrochemical capacitor C1 connects with the input anode of optocoupler GO2, the negative pole of electrochemical capacitor C1 connects with the input cathode of optocoupler GO1, and the input cathode of optocoupler GO2 connects with the input anode of optocoupler GO1; Output head anode contact resistance R4, diode D3 and the oscillating capacitance C6 successively of optocoupler GO2, the minus earth line of oscillating capacitance C6, the positive pole of oscillating capacitance C6 connects with the positive pole of diode D3, and the negative pole of output end of optocoupler GO2 connects with the 7 foot discharge ends of IC1A on time base apparatus; The negative pole of output end of optocoupler GO1 is connected to the positive pole of oscillating capacitance C6 through diode D2, and the negative pole of diode D2 connects with the positive pole of oscillating capacitance C6, the output head anode of optocoupler GO1 through resistance R3 with time base apparatus IC1A 7 foot discharge ends connect; Time base apparatus, the 8 foot power ends of IC1A connected the DC source of 12V, and time base apparatus IC1A 8 foot power ends connect with the positive pole of oscillating capacitance C6 after resistance R6 and resistance R2, the connected node of resistance R6 and resistance R2 connects with the 7 foot discharge ends of IC1A on time base apparatus; Time base apparatus IC1A 6 foot high level trigger ends and 2 foot low level trigger ends all connect with the positive pole of oscillating capacitance C6; Time base apparatus, the 3 foot outfans of IC1A were received in the base stage of audion Q3 and the base stage of audion Q4 respectively after resistance R5, connect with the grid of field effect transistor Q2 after audion Q3 is connected with the emitter stage of audion Q4, the source ground line of field effect transistor Q2, the magnetic that the drain electrode of field effect transistor Q2 connects in described magnetic amplifier successively amplifies coil L1 and main coil L2.
6. treatment of cancer device according to claim 5, it is characterized in that, magnetic amplifies coil L1 and main coil L2 and forms series arm, one termination 24V DC source of this series arm, another termination field effect transistor Q2, be parallel with by diode D1 and electric capacity C7 absorption circuit in series at the two ends of this series arm, one end that positive pole and the magnetic of diode D1 amplify coil L1 connects, and the negative pole of diode D1 connects with one end of electric capacity C7; Resistance R1 is parallel with at the two ends of electric capacity C7.
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CN109939358A (en) * | 2019-04-16 | 2019-06-28 | 吉林大学 | A kind of low-frequency range broadband magnetic field-therapeutic instrument and its application method for oncotherapy |
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Effective date of registration: 20180301 Address after: Room 1904, building No. 1, No. 136 science and technology center, the Yellow River Avenue, Hebei high tech Zone, Shijiazhuang City, Hebei Patentee after: Shijiazhuang bin Si Technology Co. Ltd. Address before: 050000 No. 1, No. 73, No. 73, nine Zhongjie, Xinhua District, Shijiazhuang City, Hebei province 601 Patentee before: Ding Jianmin |