CN105169136A - Medical syphilis hydrogel dressing and preparation method thereof - Google Patents
Medical syphilis hydrogel dressing and preparation method thereof Download PDFInfo
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- CN105169136A CN105169136A CN201510694612.XA CN201510694612A CN105169136A CN 105169136 A CN105169136 A CN 105169136A CN 201510694612 A CN201510694612 A CN 201510694612A CN 105169136 A CN105169136 A CN 105169136A
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Abstract
The invention relates to the technical field of medical dressings, and in particular relates to a medical syphilis hydrogel dressing and a preparation method thereof. The medical syphilis hydrogel dressing consists of a glabrous greenbrier rhizome extract, a honeysuckle flower extract, a Siberian cocklour fruit extract, a Japanese honeysuckle stem extract, a densefruit pittany root-bark extract, a purslane herb extract, a Mongolian dandelion herb extract, a divaricate saposhnikovia root extract, a akebia stem extract, a coix seed extract, a herb of common knotgrass extract, a clematis root extract, a licorice root extract, peppermint, sodium salicylate, acetyl salicylic acid, carbomer and purified water. In the medical syphilis hydrogel dressing provided by the invention, except for accessories, all the components are pure traditional Chinese medicines, so that the medical syphilis hydrogel dressing has low irritation and no toxic or side effects, is safe to use, is good in permeability, good in treatment effect and quick in effect, and can be used for treating syphilis.
Description
Technical field
The present invention relates to medical dressing technical field, be specifically related to a kind of medical syphilis aerogel dressing and preparation method thereof.
Background technology
Syphilis is a kind of common sexually transmitted disease (STD), have accumulated many experiences in the process that the mankind struggle in same syphilis, in the record of Ancient Times in China early useful mercurialization syphilis.Treatment syphilis experienced by mercurialization, arsenic agent treatment, penicillin treat three developing periods.Current penicillin is the medicine of first-selected treatment syphilis, also has the antibiotic beyond application penicillin to be used for treating treponema pallidum, if erythromycin series is as azithromycin, and Roxithromycin, erythromycin ethylsuccinate; Tetracyclines as doxycycline, oxytetracycline, streptomycin.Tried out ceftriaxone sodium again in recent years, cefotaxime sodium is treated.Penicillin is the medicine of Effective Anti treponema pallidum, and syphilis is very responsive to penicillin, and treponema pallidum doubling time is 30-33 hour, when serum-concentration is higher than 0.03 units per ml, can kill treponema pallidum.But owing to causing a large amount of spirillum death to release foreign preteins after penicillin injection, Jarisch-Herxheimer can be caused to react.Within 3-12 hour, occur heating after injection to early stage patient, weak and skin lesion or periostitis pain symptom etc. increase the weight of, but general and not serious, can alleviate in 24 hours.Occasionally can causing Focal reaction to tertiary syphilis, occurring angina pectoris, arrhythmia as injected rear cardiovascular syphilis patient, aortic aneurysm even occur and breaks; Also can make neurosyphilis exacerbation of symptoms, increase the weight of as deafness or occur headache syndromes.It is good that syphilis patient looks forward to there is a kind of therapeutic effect, and instant effect, to the medical dressing of human non-toxic's side effect.
Summary of the invention
In order to overcome the shortcoming and defect existed in prior art, the object of the present invention is to provide a kind of medical syphilis aerogel dressing, this medical syphilis aerogel dressing various component except batching is pure Chinese medicine, zest is little, has no side effect, use safety, good penetrability, therapeutic effect is good, instant effect, can be used for the treatment of syphilis.
Another object of the present invention is to the preparation method providing a kind of medical syphilis aerogel dressing, this preparation method technique is simple, and cheaper starting materials is easy to get, convenient operation and control, and production cost is low, can large-scale industrial production.
Object of the present invention is achieved through the following technical solutions: a kind of medical syphilis aerogel dressing, and it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 20%-30%
Flos Lonicerae extract 1.5%-2.5%
Fructus Xanthii extract 1%-2%
Caulis Lonicerae extract 1%-2%
Cortex Dictamni extract 1%-2%
Herba portulacae extract 1%-2%
Herba Taraxaci extract 1%-2%
Radix Saposhnikoviae extract 1%-2%
Caulis Akebiae extract 1%-2%
Semen Coicis extract 1%-2%
Herba Polygoni Avicularis extract 1%-2%
Radix Clematidis extract 1%-2%
Radix Glycyrrhizae extract 0.5%-1.5%
Herba Menthae 0.3%-0.7%
Salicylic acid receives 3%-7%
Aspirin 3%-7%
Carbomer 2%-4%
Purified water surplus.
Rhizoma Smilacis Glabrae, nature and flavor: sweet, light are flat; Gui Jing: return liver, stomach warp; Effect: removing toxic substances, dehumidifying, easing joint movement; Cure mainly: syphilis and the limbs contracture caused by mercurialism, bones and muscles pain; Damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies.
Flos Lonicerae, cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treat effect of wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.
Fructus Xanthii, nature and flavor: bitter in the mouth, sweet, pungent, warm in nature; Gui Jing: return lung, Liver Channel; Effect: dispersing wind-cold, clearing the nasal passage, wind-damp dispelling, pain relieving; Cure mainly: for anemofrigid cold, nasal sinusitis, rheumatic arthralgia, the cards such as rubella pruritus.
Caulis Lonicerae, nature and flavor: sweet, cold; Gui Jing: attach to the lung and stomach meridians; Function cures mainly: heat-clearing and toxic substances removing, dispelling wind dredging collateral.For epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle skin infection, beriberoid pyretic arthralgia, redness and swelling of joints burning pain.
Cortex Dictamni, nature and flavor: bitter, salty, cold; Gui Jing: spleen channel, lung meridian, small intestine meridian, stomach warp, urinary bladder channel; Function: heat clearing and damp drying, dispelling wind for relieving itching, removing toxic substances; Cure mainly: the rubella caused by wind heat noxious dampness, eczema, scabies, jaundice, damp-heat arthralgia.
Herba Portulacae, heat-clearing and toxic substances removing, loose blood detumescence.Control hematodiarrhoea pus and blood, pyretic stranguria, stranguria with blood, leukorrhagia, carbuncle malignant boil, erysipelas, trace scrofula.For damp and hot caused diarrhoea, dysentery, often join Rhizoma Coptidis, the Radix Aucklandiae.Take orally or smash juice external application, controlling carbuncle.Also for having blood in stool, metrorrhagia, have anastalsis.
Herba Taraxaci, nature and flavor are sweet, micro-hardship, cold; Return liver, stomach warp; There are the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting; Control pyretic toxicity, carbuncle, skin infection, abscess of internal organ, conjunctival congestion and swelling pain, damp and hot, the puckery pain of jaundice, dribbling urination, furuncle swelling toxin, acute mastitis, scrofula, toothache, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.Control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection etc.
Radix Saposhnikoviae, nature and flavor: acrid in the mouth, sweet, slightly warm in nature; Gui Jing: return bladder, lung, spleen, Liver Channel; Effect: expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion; Cure mainly: for diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus just, insufficiency of the spleen leading to overabundance of dampness.
Caulis Akebiae, nature and flavor: bitter in the mouth, cold in nature; Gui Jing: GUIXIN, small intestinal, urinary bladder channel; Function: have inducing diuresis for treating stranguria syndrome, clear away heart-fire relieving restlessness, the effect of stimulating milk secretion of stimulating the menstrual flow; Cure mainly: for stranguria, edema, vexed dark coloured urine, aphtha of the mouth and tongue, amenorrhea breast is few, damp and hot arthralgia pain.
Semen Coicis, nature and flavor: sweet; Light; Be slightly cold; Gui Jing: spleen; Lung; Kidney channel; Function cures mainly: Semen Coicis: dampness removing spleen invigorating; Arthralgia relieving by relaxing muscles and tendons; Clearing away heat and discharging pus.Main edema; Foot gas; Dribbling urination; Damp-warm diseases; To have loose bowels leukorrhagia; Rheumatic arthralgia; The contracture of muscle arteries and veins; Lung abscess; Intestinal carbuncle; Verruca plana.
Herba Polygoni Avicularis, nature and flavor: bitter, are slightly cold; Gui Jing: return urinary bladder channel; Hardship falls row, tonneau bladder, bitter dry again can parasite killing removing damp to relieve itching, be mainly used in drenching pain and eczema.
Radix Clematidis, expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the loose hypochondriac lump.Cure mainly gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, knee joint cold type of pain, the contracture of muscle arteries and veins, joint stuffiness, beriberi, malaria, lump in the abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs.
Medical syphilis aerogel dressing of the present invention is by adopting Rhizoma Smilacis Glabrae extract, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, the plurality of Chinese such as Radix Clematidis extract and Radix Glycyrrhizae extract, be aided with Herba Menthae, salicylic acid is received, aspirin and carbomer, utilize the synergism between each supplementary material, obtained medical syphilis aerogel dressing various component except batching is pure Chinese medicine, zest is little, have no side effect, use safety, good penetrability, therapeutic effect is good, instant effect, can be used for the treatment of syphilis.
More preferred, it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 20%-25%
Flos Lonicerae extract 1.5%-2%
Fructus Xanthii extract 1%-1.5%
Caulis Lonicerae extract 1%-1.5%
Cortex Dictamni extract 1%-1.5%
Herba portulacae extract 1%-1.5%
Herba Taraxaci extract 1%-1.5%
Radix Saposhnikoviae extract 1%-1.5%
Caulis Akebiae extract 1%-1.5%
Semen Coicis extract 1%-1.5%
Herba Polygoni Avicularis extract 1%-1.5%
Radix Clematidis extract 1%-1.5%
Radix Glycyrrhizae extract 0.5%-1%
Herba Menthae 0.3%-0.5%
Salicylic acid receives 3%-5%
Aspirin 3%-5%
Carbomer 2%-3%
Purified water surplus.
Another is preferred, and it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 22%-28%
Flos Lonicerae extract 1.8%-2.2%
Fructus Xanthii extract 1.2%-1.8%
Caulis Lonicerae extract 1.2%-1.8%
Cortex Dictamni extract 1.2%-1.8%
Herba portulacae extract 1.2%-1.8%
Herba Taraxaci extract 1.2%-1.8%
Radix Saposhnikoviae extract 1.2%-1.8%
Caulis Akebiae extract 1.2%-1.8%
Semen Coicis extract 1.2%-1.8%
Herba Polygoni Avicularis extract 1.2%-1.8%
Radix Clematidis extract 1.2%-1.8%
Radix Glycyrrhizae extract 0.8%-1.2%
Herba Menthae 0.4%-0.6%
Salicylic acid receives 4%-6%
Aspirin 4%-6%
Carbomer 2.5%-3.5%
Purified water surplus.
Another is preferred, and it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 25%-30%
Flos Lonicerae extract 2%-2.5%
Fructus Xanthii extract 1.5%-2%
Caulis Lonicerae extract 1.5%-2%
Cortex Dictamni extract 1.5%-2%
Herba portulacae extract 1.5%-2%
Herba Taraxaci extract 1.5%-2%
Radix Saposhnikoviae extract 1.5%-2%
Caulis Akebiae extract 1.5%-2%
Semen Coicis extract 1.5%-2%
Herba Polygoni Avicularis extract 1.5%-2%
Radix Clematidis extract 1.5%-2%
Radix Glycyrrhizae extract 1%-1.5%
Herba Menthae 0.5%-0.7%
Salicylic acid receives 5%-7%
Aspirin 5%-7%
Carbomer 3%-4%
Purified water surplus.
More preferred, it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 22%
Flos Lonicerae extract 1.8%
Fructus Xanthii extract 1.2%
Caulis Lonicerae extract 1.2%
Cortex Dictamni extract 1.2%
Herba portulacae extract 1.2%
Herba Taraxaci extract 1.2%
Radix Saposhnikoviae extract 1.2%
Caulis Akebiae extract 1.2%
Semen Coicis extract 1.2%
Herba Polygoni Avicularis extract 1.2%
Radix Clematidis extract 1.2%
Radix Glycyrrhizae extract 0.8%
Herba Menthae 0.4%
Salicylic acid receives 4%
Aspirin 4%
Carbomer 2.5%
Purified water surplus.
Another is preferred, and it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 25%
Flos Lonicerae extract 2%
Fructus Xanthii extract 1.5%
Caulis Lonicerae extract 1.5%
Cortex Dictamni extract 1.5%
Herba portulacae extract 1.5%
Herba Taraxaci extract 1.5%
Radix Saposhnikoviae extract 1.5%
Caulis Akebiae extract 1.5%
Semen Coicis extract 1.5%
Herba Polygoni Avicularis extract 1.5%
Radix Clematidis extract 1.5%
Radix Glycyrrhizae extract 1%
Herba Menthae 0.5%
Salicylic acid receives 5%
Aspirin 5%
Carbomer 3%
Purified water surplus.
Another is preferred, and it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 28%
Flos Lonicerae extract 2.2%
Fructus Xanthii extract 1.8%
Caulis Lonicerae extract 1.8%
Cortex Dictamni extract 1.8%
Herba portulacae extract 1.8%
Herba Taraxaci extract 1.8%
Radix Saposhnikoviae extract 1.8%
Caulis Akebiae extract 1.8%
Semen Coicis extract 1.8%
Herba Polygoni Avicularis extract 1.8%
Radix Clematidis extract 1.8%
Radix Glycyrrhizae extract 1.2%
Herba Menthae 0.6%
Salicylic acid receives 6%
Aspirin 6%
Carbomer 3.5%
Purified water surplus.
Preferably, described Rhizoma Smilacis Glabrae extract is the Rhizoma Smilacis Glabrae extract through 80-100 mesh screen; Described Flos Lonicerae extract is the Flos Lonicerae extract through 80-100 mesh screen; Described Fructus Xanthii extract is the Fructus Xanthii extract through 80-100 mesh screen; Described Caulis Lonicerae extract is the Caulis Lonicerae extract through 80-100 mesh screen; Described Cortex Dictamni extract is the Cortex Dictamni extract through 80-100 mesh screen; Described Herba portulacae extract is the Herba portulacae extract through 80-100 mesh screen; Described Herba Taraxaci extract is the Herba Taraxaci extract through 80-100 mesh screen.
Preferably, described Radix Saposhnikoviae extract is the Radix Saposhnikoviae extract through 80-100 mesh screen; Described Caulis Akebiae extract is the Caulis Akebiae extract through 80-100 mesh screen; Described Semen Coicis extract is the Semen Coicis extract through 80-100 mesh screen; Described Herba Polygoni Avicularis extract is the Herba Polygoni Avicularis extract through 80-100 mesh screen; Described Radix Clematidis extract is the Radix Clematidis extract through 80-100 mesh screen; Described Radix Glycyrrhizae extract is the Radix Glycyrrhizae extract through 80-100 mesh screen.
A preparation method for medical syphilis aerogel dressing, comprises the steps:
Steps A, weighing: weigh the Rhizoma Smilacis Glabrae extract of formula ratio, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, Radix Clematidis extract, Radix Glycyrrhizae extract, Herba Menthae, salicylic acid are received, aspirin, carbomer and purified water;
Step B, preparation: load weighted for steps A Rhizoma Smilacis Glabrae extract, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, Radix Clematidis extract, Radix Glycyrrhizae extract, Herba Menthae, salicylic acid are received, aspirin, carbomer and purified water put into container and be stirred to evenly, obtain medical syphilis aerogel dressing.
Preparation method technique of the present invention is simple, and cheaper starting materials is easy to get, convenient operation and control, and production cost is low, can large-scale industrial production.
Beneficial effect of the present invention is: medical syphilis aerogel dressing of the present invention various component except batching is pure Chinese medicine, and zest is little, has no side effect, use safety, good penetrability, and therapeutic effect is good, instant effect, can be used for the treatment of syphilis.
Preparation method technique of the present invention is simple, and cheaper starting materials is easy to get, convenient operation and control, and production cost is low, can large-scale industrial production.
Detailed description of the invention
For the ease of the understanding of those skilled in the art, below in conjunction with embodiment, the present invention is further illustrated, and the content that embodiment is mentioned not is limitation of the invention.
Embodiment 1
A kind of medical syphilis aerogel dressing, it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 20%
Flos Lonicerae extract 1.5%
Fructus Xanthii extract 1%
Caulis Lonicerae extract 1%
Cortex Dictamni extract 1%
Herba portulacae extract 1%
Herba Taraxaci extract 1%
Radix Saposhnikoviae extract 1%
Caulis Akebiae extract 1%
Semen Coicis extract 1%
Herba Polygoni Avicularis extract 1%
Radix Clematidis extract 1%
Radix Glycyrrhizae extract 0.5%
Herba Menthae 0.3%
Salicylic acid receives 3%
Aspirin 3%
Carbomer 2%
Purified water surplus.
Described Rhizoma Smilacis Glabrae extract is the Rhizoma Smilacis Glabrae extract through 80 mesh screen; Described Flos Lonicerae extract is the Flos Lonicerae extract through 80 mesh screen; Described Fructus Xanthii extract is the Fructus Xanthii extract through 80 mesh screen; Described Caulis Lonicerae extract is the Caulis Lonicerae extract through 80 mesh screen; Described Cortex Dictamni extract is the Cortex Dictamni extract through 80 mesh screen; Described Herba portulacae extract is the Herba portulacae extract through 80 mesh screen; Described Herba Taraxaci extract is the Herba Taraxaci extract through 80 mesh screen.
Described Radix Saposhnikoviae extract is the Radix Saposhnikoviae extract through 80 mesh screen; Described Caulis Akebiae extract is the Caulis Akebiae extract through 80 mesh screen; Described Semen Coicis extract is the Semen Coicis extract through 80 mesh screen; Described Herba Polygoni Avicularis extract is the Herba Polygoni Avicularis extract through 80 mesh screen; Described Radix Clematidis extract is the Radix Clematidis extract through 80 mesh screen; Described Radix Glycyrrhizae extract is the Radix Glycyrrhizae extract through 80 mesh screen.
The Rhizoma Smilacis Glabrae extract that the present invention adopts, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, Radix Clematidis extract and Radix Glycyrrhizae extract are commercially available Chinese medicine extract.
A preparation method for medical syphilis aerogel dressing, comprises the steps:
Steps A, weighing: weigh the Rhizoma Smilacis Glabrae extract of formula ratio, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, Radix Clematidis extract, Radix Glycyrrhizae extract, Herba Menthae, salicylic acid are received, aspirin, carbomer and purified water;
Step B, preparation: load weighted for steps A Rhizoma Smilacis Glabrae extract, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, Radix Clematidis extract, Radix Glycyrrhizae extract, Herba Menthae, salicylic acid are received, aspirin, carbomer and purified water put into container and be stirred to evenly, obtain medical syphilis aerogel dressing.
Clinical practice example 1: Mr. Zhang, 47 years old, symptom was penis and glans penis caries callosa, is diagnosed as primary syphilis, adopted the medical syphilis aerogel dressing of the embodiment of the present invention 1, the symptom every day position drug of topical application three times, and medication is after 15 days, transference cure.
Embodiment 2
A kind of medical syphilis aerogel dressing, it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 22%
Flos Lonicerae extract 1.8%
Fructus Xanthii extract 1.2%
Caulis Lonicerae extract 1.2%
Cortex Dictamni extract 1.2%
Herba portulacae extract 1.2%
Herba Taraxaci extract 1.2%
Radix Saposhnikoviae extract 1.2%
Caulis Akebiae extract 1.2%
Semen Coicis extract 1.2%
Herba Polygoni Avicularis extract 1.2%
Radix Clematidis extract 1.2%
Radix Glycyrrhizae extract 0.8%
Herba Menthae 0.4%
Salicylic acid receives 4%
Aspirin 4%
Carbomer 2.5%
Purified water surplus.
Described Rhizoma Smilacis Glabrae extract is the Rhizoma Smilacis Glabrae extract through 90 mesh screen; Described Flos Lonicerae extract is the Flos Lonicerae extract through 90 mesh screen; Described Fructus Xanthii extract is the Fructus Xanthii extract through 90 mesh screen; Described Caulis Lonicerae extract is the Caulis Lonicerae extract through 90 mesh screen; Described Cortex Dictamni extract is the Cortex Dictamni extract through 90 mesh screen; Described Herba portulacae extract is the Herba portulacae extract through 90 mesh screen; Described Herba Taraxaci extract is the Herba Taraxaci extract through 90 mesh screen.
Described Radix Saposhnikoviae extract is the Radix Saposhnikoviae extract through 90 mesh screen; Described Caulis Akebiae extract is the Caulis Akebiae extract through 90 mesh screen; Described Semen Coicis extract is the Semen Coicis extract through 90 mesh screen; Described Herba Polygoni Avicularis extract is the Herba Polygoni Avicularis extract through 90 mesh screen; Described Radix Clematidis extract is the Radix Clematidis extract through 90 mesh screen; Described Radix Glycyrrhizae extract is the Radix Glycyrrhizae extract through 90 mesh screen.
A preparation method for medical syphilis aerogel dressing, comprises the steps:
Steps A, weighing: weigh the Rhizoma Smilacis Glabrae extract of formula ratio, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, Radix Clematidis extract, Radix Glycyrrhizae extract, Herba Menthae, salicylic acid are received, aspirin, carbomer and purified water;
Step B, preparation: load weighted for steps A Rhizoma Smilacis Glabrae extract, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, Radix Clematidis extract, Radix Glycyrrhizae extract, Herba Menthae, salicylic acid are received, aspirin, carbomer and purified water put into container and be stirred to evenly, obtain medical syphilis aerogel dressing.
Clinical practice example 2: Mr. Xu, 32 years old, symptom was coronary sulcus and foreskin caries callosa, is diagnosed as primary syphilis, adopted the medical syphilis aerogel dressing of the embodiment of the present invention 2, the symptom every day position drug of topical application three times, and medication is after 15 days, transference cure.
Embodiment 3
A kind of medical syphilis aerogel dressing, it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 25%
Flos Lonicerae extract 2%
Fructus Xanthii extract 1.5%
Caulis Lonicerae extract 1.5%
Cortex Dictamni extract 1.5%
Herba portulacae extract 1.5%
Herba Taraxaci extract 1.5%
Radix Saposhnikoviae extract 1.5%
Caulis Akebiae extract 1.5%
Semen Coicis extract 1.5%
Herba Polygoni Avicularis extract 1.5%
Radix Clematidis extract 1.5%
Radix Glycyrrhizae extract 1%
Herba Menthae 0.5%
Salicylic acid receives 5%
Aspirin 5%
Carbomer 3%
Purified water surplus.
Described Rhizoma Smilacis Glabrae extract is the Rhizoma Smilacis Glabrae extract through 90 mesh screen; Described Flos Lonicerae extract is the Flos Lonicerae extract through 90 mesh screen; Described Fructus Xanthii extract is the Fructus Xanthii extract through 90 mesh screen; Described Caulis Lonicerae extract is the Caulis Lonicerae extract through 90 mesh screen; Described Cortex Dictamni extract is the Cortex Dictamni extract through 90 mesh screen; Described Herba portulacae extract is the Herba portulacae extract through 90 mesh screen; Described Herba Taraxaci extract is the Herba Taraxaci extract through 90 mesh screen.
Described Radix Saposhnikoviae extract is the Radix Saposhnikoviae extract through 90 mesh screen; Described Caulis Akebiae extract is the Caulis Akebiae extract through 90 mesh screen; Described Semen Coicis extract is the Semen Coicis extract through 90 mesh screen; Described Herba Polygoni Avicularis extract is the Herba Polygoni Avicularis extract through 90 mesh screen; Described Radix Clematidis extract is the Radix Clematidis extract through 90 mesh screen; Described Radix Glycyrrhizae extract is the Radix Glycyrrhizae extract through 90 mesh screen.
A preparation method for medical syphilis aerogel dressing, comprises the steps:
Steps A, weighing: weigh the Rhizoma Smilacis Glabrae extract of formula ratio, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, Radix Clematidis extract, Radix Glycyrrhizae extract, Herba Menthae, salicylic acid are received, aspirin, carbomer and purified water;
Step B, preparation: load weighted for steps A Rhizoma Smilacis Glabrae extract, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, Radix Clematidis extract, Radix Glycyrrhizae extract, Herba Menthae, salicylic acid are received, aspirin, carbomer and purified water put into container and be stirred to evenly, obtain medical syphilis aerogel dressing.
Clinical practice example 3: Bruin, 38 years old, symptom was anus caries callosa, is diagnosed as primary syphilis, adopted the medical syphilis aerogel dressing of the embodiment of the present invention 3, the symptom every day position drug of topical application three times, and medication is after 15 days, transference cure.
Embodiment 4
A kind of medical syphilis aerogel dressing, it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 28%
Flos Lonicerae extract 2.2%
Fructus Xanthii extract 1.8%
Caulis Lonicerae extract 1.8%
Cortex Dictamni extract 1.8%
Herba portulacae extract 1.8%
Herba Taraxaci extract 1.8%
Radix Saposhnikoviae extract 1.8%
Caulis Akebiae extract 1.8%
Semen Coicis extract 1.8%
Herba Polygoni Avicularis extract 1.8%
Radix Clematidis extract 1.8%
Radix Glycyrrhizae extract 1.2%
Herba Menthae 0.6%
Salicylic acid receives 6%
Aspirin 6%
Carbomer 3.5%
Purified water surplus.
Described Rhizoma Smilacis Glabrae extract is the Rhizoma Smilacis Glabrae extract through 90 mesh screen; Described Flos Lonicerae extract is the Flos Lonicerae extract through 90 mesh screen; Described Fructus Xanthii extract is the Fructus Xanthii extract through 90 mesh screen; Described Caulis Lonicerae extract is the Caulis Lonicerae extract through 90 mesh screen; Described Cortex Dictamni extract is the Cortex Dictamni extract through 90 mesh screen; Described Herba portulacae extract is the Herba portulacae extract through 90 mesh screen; Described Herba Taraxaci extract is the Herba Taraxaci extract through 90 mesh screen.
Described Radix Saposhnikoviae extract is the Radix Saposhnikoviae extract through 90 mesh screen; Described Caulis Akebiae extract is the Caulis Akebiae extract through 90 mesh screen; Described Semen Coicis extract is the Semen Coicis extract through 90 mesh screen; Described Herba Polygoni Avicularis extract is the Herba Polygoni Avicularis extract through 90 mesh screen; Described Radix Clematidis extract is the Radix Clematidis extract through 90 mesh screen; Described Radix Glycyrrhizae extract is the Radix Glycyrrhizae extract through 90 mesh screen.
A preparation method for medical syphilis aerogel dressing, comprises the steps:
Steps A, weighing: weigh the Rhizoma Smilacis Glabrae extract of formula ratio, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, Radix Clematidis extract, Radix Glycyrrhizae extract, Herba Menthae, salicylic acid are received, aspirin, carbomer and purified water;
Step B, preparation: load weighted for steps A Rhizoma Smilacis Glabrae extract, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, Radix Clematidis extract, Radix Glycyrrhizae extract, Herba Menthae, salicylic acid are received, aspirin, carbomer and purified water put into container and be stirred to evenly, obtain medical syphilis aerogel dressing.
Clinical practice example 4: Mrs Wang, 37 years old, sized by symptom, labia and clitoris caries callosa, be diagnosed as primary syphilis, adopts the medical syphilis aerogel dressing of the embodiment of the present invention 4, the symptom every day position drug of topical application three times, and medication is after 15 days, transference cure.
Embodiment 5
A kind of medical syphilis aerogel dressing, it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 30%
Flos Lonicerae extract 2.5%
Fructus Xanthii extract 2%
Caulis Lonicerae extract 2%
Cortex Dictamni extract 2%
Herba portulacae extract 2%
Herba Taraxaci extract 2%
Radix Saposhnikoviae extract 2%
Caulis Akebiae extract 2%
Semen Coicis extract 2%
Herba Polygoni Avicularis extract 2%
Radix Clematidis extract 2%
Radix Glycyrrhizae extract 1.5%
Herba Menthae 0.7%
Salicylic acid receives 7%
Aspirin 7%
Carbomer 4%
Purified water surplus.
Described Rhizoma Smilacis Glabrae extract is the Rhizoma Smilacis Glabrae extract through 100 mesh screen; Described Flos Lonicerae extract is the Flos Lonicerae extract through 100 mesh screen; Described Fructus Xanthii extract is the Fructus Xanthii extract through 100 mesh screen; Described Caulis Lonicerae extract is the Caulis Lonicerae extract through 100 mesh screen; Described Cortex Dictamni extract is the Cortex Dictamni extract through 100 mesh screen; Described Herba portulacae extract is the Herba portulacae extract through 100 mesh screen; Described Herba Taraxaci extract is the Herba Taraxaci extract through 100 mesh screen.
Described Radix Saposhnikoviae extract is the Radix Saposhnikoviae extract through 100 mesh screen; Described Caulis Akebiae extract is the Caulis Akebiae extract through 100 mesh screen; Described Semen Coicis extract is the Semen Coicis extract through 100 mesh screen; Described Herba Polygoni Avicularis extract is the Herba Polygoni Avicularis extract through 100 mesh screen; Described Radix Clematidis extract is the Radix Clematidis extract through 100 mesh screen; Described Radix Glycyrrhizae extract is the Radix Glycyrrhizae extract through 100 mesh screen.
A preparation method for medical syphilis aerogel dressing, comprises the steps:
Steps A, weighing: weigh the Rhizoma Smilacis Glabrae extract of formula ratio, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, Radix Clematidis extract, Radix Glycyrrhizae extract, Herba Menthae, salicylic acid are received, aspirin, carbomer and purified water;
Step B, preparation: load weighted for steps A Rhizoma Smilacis Glabrae extract, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, Radix Clematidis extract, Radix Glycyrrhizae extract, Herba Menthae, salicylic acid are received, aspirin, carbomer and purified water put into container and be stirred to evenly, obtain medical syphilis aerogel dressing.
Clinical practice example 5: Mrs Liang, 41 years old, symptom was cervix uteri caries callosa, is diagnosed as primary syphilis, adopted the medical syphilis aerogel dressing of the embodiment of the present invention 5, the symptom every day position drug of topical application three times, and medication is after 15 days, transference cure.
Clinical observation on the therapeutic effect result shows, and medical syphilis aerogel dressing zest of the present invention is little, has no side effect, use safety, and good penetrability, therapeutic effect is good, instant effect, can be used for the treatment of syphilis.
The medical syphilis aerogel dressing obtained to embodiment 1-5 carries out pharmacology test respectively, and experimental result is as follows:
Test 1: fungistatic effect
By " medicine Micro biological Tests handbook " the 18th chapter Section 1 cup-plate method test, measurement result is see table 1.
Table 1
Bacteriostatic diameter (mm) | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 |
Staphylococcus aureus | 25.6±0.9 | 26.4±0.7 | 26.1±0.8 | 27.2±0.9 | 25.7±0.6 |
Escherichia coli | 21.1±0.7 | 22.2±0.6 | 21.5±0.9 | 22.6±1.0 | 23.3±0.8 |
Candida albicans | 28.5±0.9 | 29.1±0.7 | 28.2±0.8 | 29.4±0.7 | 30.2±0.6 |
Bacillus pyocyaneus | 15.8±1.0 | 16.2±0.9 | 15.6±0.6 | 16.5±0.9 | 17.2±0.8 |
As can be seen from Table 1, the medical syphilis aerogel dressing that the present invention obtains all has obvious inhibition zone, illustrates there is obvious inhibitory action to the growth of gold-coloured staphylococci, escherichia coli, Candida albicans, bacillus pyocyaneus.
Test 2: liquid dressing sample skin irritation index (PII) measures
Measure by the closed sensitization test (STT) method of GB/T16886.10-2000 regulation, testing result is see table 2.
Table 2
Test event | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 |
Skin irritation index | 0 | 0 | 0 | 0 | 0 |
Sensitization of skin | Nothing | Nothing | Nothing | Nothing | Nothing |
As can be seen from Table 2, the medical syphilis aerogel dressing that the present invention obtains all reacts without skin irritation and sensitization of skin.
Test 3: biocompatibility experiment
Inject in white rabbit body respectively by the medical syphilis aerogel dressing of embodiment 1-5, timing is observed, continuous 8 days body weight, feed, body temperature, movable without exception.Illustrate that the medical syphilis aerogel dressing that the present invention obtains has good biocompatibility.
Above-described embodiment is the present invention's preferably implementation, and in addition, the present invention can also realize by alternate manner, and any apparent replacement is all within protection scope of the present invention without departing from the inventive concept of the premise.
Claims (10)
1. a medical syphilis aerogel dressing, is characterized in that: it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 20%-30%
Flos Lonicerae extract 1.5%-2.5%
Fructus Xanthii extract 1%-2%
Caulis Lonicerae extract 1%-2%
Cortex Dictamni extract 1%-2%
Herba portulacae extract 1%-2%
Herba Taraxaci extract 1%-2%
Radix Saposhnikoviae extract 1%-2%
Caulis Akebiae extract 1%-2%
Semen Coicis extract 1%-2%
Herba Polygoni Avicularis extract 1%-2%
Radix Clematidis extract 1%-2%
Radix Glycyrrhizae extract 0.5%-1.5%
Herba Menthae 0.3%-0.7%
Salicylic acid receives 3%-7%
Aspirin 3%-7%
Carbomer 2%-4%
Purified water surplus.
2. the medical syphilis aerogel dressing of one according to claim 1, is characterized in that: it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 20%-25%
Flos Lonicerae extract 1.5%-2%
Fructus Xanthii extract 1%-1.5%
Caulis Lonicerae extract 1%-1.5%
Cortex Dictamni extract 1%-1.5%
Herba portulacae extract 1%-1.5%
Herba Taraxaci extract 1%-1.5%
Radix Saposhnikoviae extract 1%-1.5%
Caulis Akebiae extract 1%-1.5%
Semen Coicis extract 1%-1.5%
Herba Polygoni Avicularis extract 1%-1.5%
Radix Clematidis extract 1%-1.5%
Radix Glycyrrhizae extract 0.5%-1%
Herba Menthae 0.3%-0.5%
Salicylic acid receives 3%-5%
Aspirin 3%-5%
Carbomer 2%-3%
Purified water surplus.
3. the medical syphilis aerogel dressing of one according to claim 1, is characterized in that: it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 22%-28%
Flos Lonicerae extract 1.8%-2.2%
Fructus Xanthii extract 1.2%-1.8%
Caulis Lonicerae extract 1.2%-1.8%
Cortex Dictamni extract 1.2%-1.8%
Herba portulacae extract 1.2%-1.8%
Herba Taraxaci extract 1.2%-1.8%
Radix Saposhnikoviae extract 1.2%-1.8%
Caulis Akebiae extract 1.2%-1.8%
Semen Coicis extract 1.2%-1.8%
Herba Polygoni Avicularis extract 1.2%-1.8%
Radix Clematidis extract 1.2%-1.8%
Radix Glycyrrhizae extract 0.8%-1.2%
Herba Menthae 0.4%-0.6%
Salicylic acid receives 4%-6%
Aspirin 4%-6%
Carbomer 2.5%-3.5%
Purified water surplus.
4. the medical syphilis aerogel dressing of one according to claim 1, is characterized in that: it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 25%-30%
Flos Lonicerae extract 2%-2.5%
Fructus Xanthii extract 1.5%-2%
Caulis Lonicerae extract 1.5%-2%
Cortex Dictamni extract 1.5%-2%
Herba portulacae extract 1.5%-2%
Herba Taraxaci extract 1.5%-2%
Radix Saposhnikoviae extract 1.5%-2%
Caulis Akebiae extract 1.5%-2%
Semen Coicis extract 1.5%-2%
Herba Polygoni Avicularis extract 1.5%-2%
Radix Clematidis extract 1.5%-2%
Radix Glycyrrhizae extract 1%-1.5%
Herba Menthae 0.5%-0.7%
Salicylic acid receives 5%-7%
Aspirin 5%-7%
Carbomer 3%-4%
Purified water surplus.
5. the medical syphilis aerogel dressing of one according to claim 1, is characterized in that: it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 22%
Flos Lonicerae extract 1.8%
Fructus Xanthii extract 1.2%
Caulis Lonicerae extract 1.2%
Cortex Dictamni extract 1.2%
Herba portulacae extract 1.2%
Herba Taraxaci extract 1.2%
Radix Saposhnikoviae extract 1.2%
Caulis Akebiae extract 1.2%
Semen Coicis extract 1.2%
Herba Polygoni Avicularis extract 1.2%
Radix Clematidis extract 1.2%
Radix Glycyrrhizae extract 0.8%
Herba Menthae 0.4%
Salicylic acid receives 4%
Aspirin 4%
Carbomer 2.5%
Purified water surplus.
6. the medical syphilis aerogel dressing of one according to claim 1, is characterized in that: it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 25%
Flos Lonicerae extract 2%
Fructus Xanthii extract 1.5%
Caulis Lonicerae extract 1.5%
Cortex Dictamni extract 1.5%
Herba portulacae extract 1.5%
Herba Taraxaci extract 1.5%
Radix Saposhnikoviae extract 1.5%
Caulis Akebiae extract 1.5%
Semen Coicis extract 1.5%
Herba Polygoni Avicularis extract 1.5%
Radix Clematidis extract 1.5%
Radix Glycyrrhizae extract 1%
Herba Menthae 0.5%
Salicylic acid receives 5%
Aspirin 5%
Carbomer 3%
Purified water surplus.
7. the medical syphilis aerogel dressing of one according to claim 1, is characterized in that: it is made up of the raw material of following percentage by weight:
Rhizoma Smilacis Glabrae extract 28%
Flos Lonicerae extract 2.2%
Fructus Xanthii extract 1.8%
Caulis Lonicerae extract 1.8%
Cortex Dictamni extract 1.8%
Herba portulacae extract 1.8%
Herba Taraxaci extract 1.8%
Radix Saposhnikoviae extract 1.8%
Caulis Akebiae extract 1.8%
Semen Coicis extract 1.8%
Herba Polygoni Avicularis extract 1.8%
Radix Clematidis extract 1.8%
Radix Glycyrrhizae extract 1.2%
Herba Menthae 0.6%
Salicylic acid receives 6%
Aspirin 6%
Carbomer 3.5%
Purified water surplus.
8. the medical syphilis aerogel dressing of one according to claim 1, is characterized in that: described Rhizoma Smilacis Glabrae extract is the Rhizoma Smilacis Glabrae extract through 80-100 mesh screen; Described Flos Lonicerae extract is the Flos Lonicerae extract through 80-100 mesh screen; Described Fructus Xanthii extract is the Fructus Xanthii extract through 80-100 mesh screen; Described Caulis Lonicerae extract is the Caulis Lonicerae extract through 80-100 mesh screen; Described Cortex Dictamni extract is the Cortex Dictamni extract through 80-100 mesh screen; Described Herba portulacae extract is the Herba portulacae extract through 80-100 mesh screen; Described Herba Taraxaci extract is the Herba Taraxaci extract through 80-100 mesh screen.
9. the medical syphilis aerogel dressing of one according to claim 1, is characterized in that: described Radix Saposhnikoviae extract is the Radix Saposhnikoviae extract through 80-100 mesh screen; Described Caulis Akebiae extract is the Caulis Akebiae extract through 80-100 mesh screen; Described Semen Coicis extract is the Semen Coicis extract through 80-100 mesh screen; Described Herba Polygoni Avicularis extract is the Herba Polygoni Avicularis extract through 80-100 mesh screen; Described Radix Clematidis extract is the Radix Clematidis extract through 80-100 mesh screen; Described Radix Glycyrrhizae extract is the Radix Glycyrrhizae extract through 80-100 mesh screen.
10. the preparation method of a kind of medical syphilis aerogel dressing as described in any one of claim 1-9, is characterized in that: comprise the steps:
Steps A, weighing: weigh the Rhizoma Smilacis Glabrae extract of formula ratio, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, Radix Clematidis extract, Radix Glycyrrhizae extract, Herba Menthae, salicylic acid are received, aspirin, carbomer and purified water;
Step B, preparation: load weighted for steps A Rhizoma Smilacis Glabrae extract, Flos Lonicerae extract, Fructus Xanthii extract, Caulis Lonicerae extract, Cortex Dictamni extract, Herba portulacae extract, Herba Taraxaci extract, Radix Saposhnikoviae extract, Caulis Akebiae extract, Semen Coicis extract, Herba Polygoni Avicularis extract, Radix Clematidis extract, Radix Glycyrrhizae extract, Herba Menthae, salicylic acid are received, aspirin, carbomer and purified water put into container and be stirred to evenly, obtain medical syphilis aerogel dressing.
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CN1079388A (en) * | 1992-03-24 | 1993-12-15 | 王伊斌 | Compound antisyphilis medicine |
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CN1079388A (en) * | 1992-03-24 | 1993-12-15 | 王伊斌 | Compound antisyphilis medicine |
RU2401121C1 (en) * | 2009-05-29 | 2010-10-10 | Тимофей Георгиевич Кожока | Pharmaceutical composition based on herbal extracts for treatment and prevention of viral infections and syphilis and method of treatment and prevention of viral infections and syphilis |
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