CN105148781B - A kind of cross micro-mixer of axial symmetry log spiral - Google Patents
A kind of cross micro-mixer of axial symmetry log spiral Download PDFInfo
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- CN105148781B CN105148781B CN201510503838.7A CN201510503838A CN105148781B CN 105148781 B CN105148781 B CN 105148781B CN 201510503838 A CN201510503838 A CN 201510503838A CN 105148781 B CN105148781 B CN 105148781B
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- log spiral
- runner
- log
- baffle plate
- cross
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Abstract
The present invention discloses a kind of cross micro-mixer of axial symmetry log spiral, a cross runner, a contracted channel and several mixed cells for being sequentially connected and connecing are provided between cover plate and matrix, each mixed cell is constituted by the narrow straight channel, a log spiral runner that are connected and a log spiral baffle plate being placed in log spiral runner；Log spiral runner and log spiral baffle plate all on substantially symmetrical about its central axis, the concave surface of log spiral baffle plate face where log spiral flow channel entry point；There is gap between the edges at two ends of log spiral baffle plate and the inwall of log spiral runner；The present invention can make fluid by forming jet after narrow straight channel, and jet impulse log spiral baffle plate along log spiral baffle flows, convection current is formed with stream is carried out, increases the disturbance between fluid, so as to increase the contact area of fluid, mixed effect is significantly improved.
Description
Technical field
The present invention relates to the technical field of liquid microring array in biochip and micro-total analysis system, specifically based on separation
Restructuring and the passive type micro-mixer of wall attachment effect, realize the quick mixing of different liquids under minute yardstick.
Background technology
Microfluid system is the important component of microelectromechanical systems, and microfluidic system is of microfluid system
Important branch, may be such that the functions such as separation, sample-adding, mixing, reaction, the monitoring of conventional biochemical monitoring process are able to reality on chip
It is existing.Micro-mixer, by its efficiently quick mixed performance, is widely used in as the important component of microfluidic system
The fields such as bioanalysis, chemical synthesis, drug screening and clinical trial.For two strands or the chemical reaction of a plurality of fluids, it is necessary to
Solve the effective mixed problem between them.Because the size of micro-fluidic chip runner is in micron dimension, flowing is generally in layer
It is difficult to be sufficiently mixed between stream mode, fluid, therefore realizes that the quickly mixing of fluid under minute yardstick is extremely important.
According to the principle of mixed process, micro-mixer is generally divided into reduction laminar-type and two kinds of laminar-type of reinforcing.And weaken
Laminar-type is divided into two kinds of passive type and active microring array again.Active is blender to be exerted one's influence by outside promote to mix
Close, and passive type is to take enhancements in internal fluid, i.e., come by the fluid channel of change or arrangement different shape and structure
Control mixed process, such as fluting runner, fluid layering stream（Add barrier in runner）, serpentine flow path, induce chaotic advection etc..
For active micro-mixer, passive type micro-mixer need not add extra equipment, it is easy to process, using more square
Just.And strengthen passive type micro-mixer in fluid diffusion and mixing method on, optimizing flow passage structure and reinforcing chaotic advection
It is current putative optimal selection.
At present, the size of the fluid channel in microfluid mixer is in the range of tens to hundreds of microns, liquid in fluid channel
The Reynolds number very little of body flowing so that the mixing not being vortexed between generation, liquid relies primarily on molecule diffusion motion, during mixing
Between greatly prolonged compared to macroscopical situation and mixed effect is poor, it is therefore necessary to special mode is taken to increase the contact surface between liquid
Product strengthens convection current to improve mixing efficiency.
The content of the invention
A kind of simple structure is provided the invention aims to overcome not enough present in existing micro-mixer, can carry
The cross micro-mixer of the axial symmetry log spiral of mixing efficiency high, in achievable biochip or micro-total analysis system not
Mix with the Quick uniform between liquid, strengthen mixed effect, shorten incorporation time.
The technical solution adopted by the present invention is：The present invention includes closely sealed cover plate and matrix together, cover plate and matrix it
Between be provided with a cross runner, a contracted channel and several mixed cells for being sequentially connected and connecing, each mixed cell is equal
It is right by the narrow straight channel, a log spiral runner and be placed in log spiral runner one that are connected
Number helix baffle plate is constituted；It is connected between contracted channel and runner exit after several mixed cells concatenation；Cross runner
Outlet connection contracted channel entrance, the narrow straight channel entrance in contracted channel outlet first mixed cell of connection, last
Individual log spiral runner exit connecting passage is exported and the exit width is identical with the width of runner exit, remaining logarithmic spiral
Line runner exit is identical with narrow straight channel width；The center of contracted channel and mixed cell is right on a central shaft
Number helix runner and log spiral baffle plate are all on substantially symmetrical about its central axis；The concave surface of log spiral baffle plate faces place
Log spiral flow channel entry point.
The contour line of log spiral runner is made up of two log spirals on distribution substantially symmetrical about its central axis, logarithm spiral shell
Spin line equation is, top of its log spiral starting point positioned at log spiral baffle plate concave surface one end
At point, wrap angle sigma is 135 °, and e is the truth of a matter of natural logrithm function, and its value is 2.71828,It it is 20 μm, k is that 0.001, θ 1 is
220 °~(220 ° of+α)；
The contour line of log spiral baffle plate is that two two log spirals on distribution substantially symmetrical about its central axis are constituted, its
Log spiral equation is, its starting point is the log spiral flow channel entry point central point at place,
Cornerite β is 30 °,Be 15 μm, k be 0.001, θ 2 for 270 °~(270 ° of+β).
The present invention has following advantages after using above-mentioned technical proposal：
1st, the present invention can make fluid by forming jet after narrow straight channel, increase rate of flow of fluid, increase fluid
Reynolds number.Jet impulse log spiral baffle plate, due to the special construction of log spiral baffle plate, fluid keeps off along log spiral
Plate is flowed, and convection current is formed with stream is carried out, and increases the disturbance between fluid.
2nd, when fluid flows through log spiral baffle plate, jet attached flow can be formed on the convex surface of log spiral baffle plate, is gone out
Existing secondary flow phenomenon, increases the degree of mixing of fluid.The superposition and reinforcing of vortex system are realized by simple flow passage structure, so as to increase
The contact area of fluid is added so that mixed effect is significantly improved.
3rd, the present invention equidistant symmetrical arrangement on the sprue of cross micro-mixer separates restructuring runner, and fluid is by poly-
Splitting or integrating from, into whirlpool, circulation successively is carried out, and can be mixed with significantly more efficient contact.By microring array runner geometry change and
Fluid flow characteristics increases disturbance, i.e., increase flow-disturbing degree in two-dimensionses plane, substantially increases the passive microring array of plane formula
The mixed effect of device.
Brief description of the drawings
Fig. 1 is agent structure sectional view of the invention；
Fig. 2 is A-A sectional views in Fig. 1；
Fig. 3 is the geometry enlarged diagram of cross runner in Fig. 2；
Fig. 4 is the geometry enlarged diagram of mixed cell in Fig. 2；
Fig. 5 is fluid flow principals schematic diagram of the present invention；
In figure：1st, sprue entrance；2nd, secondary channels entrance；3rd, cover plate；4th, contracted channel；5th, narrow straight channel；6th, logarithm
Helix runner；7th, log spiral baffle plate；8th, runner exit；9th, matrix；10th, cross runner.
Specific embodiment
As depicted in figs. 1 and 2, upper and lower two parts of primary structure of the present invention point, top is divided into the cover plate 3 of the micro-mixer,
Bottom is divided into the mixing runner matrix 9 of micro-mixer.Together with cover plate 3 is closely sealed with matrix 9, it is provided between cover plate 3 and matrix 9
One runner exit 8, of cross runner 10, contracted channel 4, several narrow straight channels 5, several logarithmic spirals
Line runner 6 and several log spiral baffle plates 7.Wherein, a sprue entrance 1 and two pairs are arranged on cross runner 10
Flow channel entry point 2, two centers of secondary channels are conllinear, and sprue and two secondary channels are mutually perpendicular to constitute cross runner.
The sprue outlet import of contracted channel 4 in smoothing junction of cross runner 10, the outlet of contracted channel 4 connection first
The import of narrow straight channel 5, first outlet first entrance of log spiral runner 6 of connection of narrow straight channel 5, first logarithm
Outlet second entrance of narrow straight channel 5 of connection of helix runner 6, second outlet second logarithm of connection of narrow straight channel 5
The entrance of helix runner 6, so continuously, until the outlet of last narrow straight channel 5 connects last log spiral
The entrance of runner 6.The import of last log spiral runner 6 to exit width gradually increases, last log spiral
Runner 6 outlet it is identical with the width of runner exit 8, in addition, remaining log spiral runner 6 export with narrow straight channel
5 width is identical.Contracted channel 4 is gradually reduced from import to exit width, and the exit width of contracted channel 4 is equal to narrow straight channel
5 width.
A log spiral baffle plate 7, the concave surface of log spiral baffle plate 7 are placed in each log spiral runner 6
The entrance of log spiral runner 6 where facing, the convex surface of log spiral baffle plate 7 faces the log spiral stream at place
Road 6 is exported.There is gap, the gap supplies between the edges at two ends of log spiral baffle plate 7 and the inwall of log spiral runner 6
Fluid passes through.One is made up of a log spiral baffle plate 7 of log spiral runner 6, of narrow straight channel 5, to mix
Unit is closed, narrow straight channel 5 is connected with log spiral runner 6.Several mixed cells are connected to contractive set after mutually concatenating
Between road 4 and runner exit 8.Mutually several mixed cells of concatenation are along central axis direction equidistant placement.Log spiral baffle plate 7
Concave surface face the entrance of log spiral runner 6, the convex surface of log spiral baffle plate 7 faces log spiral runner 6 and goes out
Mouthful.
The sprue of cross runner 10, contracted channel 4, narrow straight channel 5, log spiral runner 6 and logarithmic spiral
The center of line baffle plate 7 is on a central shaft.Log spiral runner 6 and log spiral baffle plate 7 are all on central shaft pair
Claim, the central shaft is also the central shaft of cross micro-mixer of the invention.Multiple mixed cells along central shaft axially equidistant cloth
Put, number n >=3 of mixed cell.
As shown in figure 3, the entrance width of the sprue of cross runner 10 is D1,200 μm<D1<400 μm, D1 is constantly equal to
The twice of secondary channels entrance width D2.The length L1 of sprue import is 2.5 times of D1, L1=2.5 × (D1), secondary channels import
Length L3 be equal to L1, beeline L2=2 × (D1) between secondary channels and contracted channel 4.
As shown in figure 4, the axial length of narrow straight channel 5 is L4, L4=(D1)/2, the width D 3=of narrow straight channel 5
(D1)/4。
The throat width of contracted channel 4 is D1, and the Breadth Maximum of log spiral runner 6 is D1, last logarithmic spiral
The exit width of line runner 6 is Breadth Maximum D1, and identical with the width of runner exit 8 is also D1.The profile linear dimension of contracted channel 4 with
The outer contour size of log spiral runner 6 keeps identical.The contour line of log spiral runner 6 is by two on central shaft pair
The log spiral of distribution is claimed to constitute, the log spiral equation of its contour line is, institute
The wrap angle sigma of determination is 135 °, and its starting point a is located at the apex of the concave surface one end of log spiral baffle plate 7, and wherein e is natural logrithm
The truth of a matter of function, its value is about 2.71828,Be 20 μm, k be 0.001, θ 1 for 220 °~(220 ° of+α).Log spiral
Runner 6 is connected to narrow straight channel 5.The axial length of runner exit 8 is more than 500 μm and less than 1000 μm, micro-mixer
Depth be equal to (D1)/2.
The vertical range of the starting point a distance center axles of log spiral is D1/3, and the starting point a of log spiral is apart from adjacent
Log spiral runner 6 its maximum width axial distance L5 be equal to sprue import length L1, i.e. L5=L1=2.5
×(D1)。
The contour line of log spiral baffle plate 7 is that two two log spirals on distribution substantially symmetrical about its central axis are constituted,
The log spiral equation is, cornerite β is 30 °, whereinIt it is 15 μm, k is 0.001；θ2
For 270 °~(270 ° of+β)；Log spiralStarting point b be where log spiral runner
6 entrance center points, starting point b is located on central shaft, and the Weir Plate Thickness of log spiral baffle plate 7 is D4=(D1)/4.Each runner
Main structure parameters and span produce influence to the mixed performance of micro-mixer.
Sprue entrance 1, secondary channels entrance 2 and cross runner 10 are arranged on the present invention left side of micro-mixer, stream
Road outlet 8 is located at the right side of micro-mixer, and so, the entrance of each runner is exported on the right side of the runner in the left end of the runner
End, described width each means the width of fore-and-aft direction, and described length each means the axial length of left and right directions, described depth
Degree refers to the depth of above-below direction.
As shown in figure 5, during present invention work, two or three fluid of different component is respectively from a sprue import 1
Enter micro-mixer with two secondary channels imports 2, converge in cross runner 10 and enter jointly after carrying out few degree mixing
Enter its sprue, mixing now relies on molecule to spread substantially, and the degree of mixing is very weak.Subsequent fluid is more by contracted channel 4
Plant component flow contact more fully, fluid forms jet by after narrow straight channel 5, three fluid streams are extruded and accelerate,
And log spiral baffle plate 7 is impacted, because the structure of log spiral baffle plate 7 is special, fluid is along log spiral baffle plate 7 to two ends
Flowing, segment fluid flow is impacted on log spiral flow path wall, between log spiral runner 6 and log spiral baffle plate 7
Symmetrical whirlpool is formed, increases flow disturbance.When fluid passes through log spiral baffle plate 7, can be in the convex of log spiral baffle plate 7
Face forms jet attached flow, secondary flow phenomenon occurs, increases the degree of mixing of fluid.Fluid is by more than three same mixture units
Afterwards, repeated contraction, into whirlpool, dispersion, attached wall into whirlpool process, so as to increased the contact area of fluid so that mixed effect obtain
Significantly improve.Finally flowed out from the runner exit 8 of fluid micro-mixer, complete mixed process.
One embodiment of the present of invention presented below：
The present embodiment is using the CFD software fluid ethanol C different to two kinds2H6O solution and water mixed flow in the present invention
It is dynamic to be simulated.It is 200 μm to use sprue entrance width D1, and the entrance width D2 of secondary channels is 100 μm.Sprue import
Length L1 and the length L3 of secondary channels import are 500 μm, and the beeline L2 between secondary channels 10 and the entrance of contracted channel 4 is
400 μm, the axial length L 4 of narrow straight channel 5 is 100 μm, width D 3 is 50 μm, and the contour line of log spiral baffle plate 7 is two
Bar on log spiral substantially symmetrical about its central axis, its equationIdentified cornerite β is 30 °, is risen
Point b in the entrance center point of log spiral runner 6, whereinIt it is 15 μm, k is 0.001；θ 2 be 270 °~(270 ° of+β), it is right
The thickness of number helix baffle plate 7 is D4=50 μm.The contour line of log spiral runner 6 be two on center line it is symmetrical point
One section of log spiral of cloth, its equation, identified wrap angle sigma is 135 °, and starting point a is
The inner arc summit of log spiral baffle plate 7, wherein e is the truth of a matter of natural logrithm function, and its value is about 2.71828,It is 20 μ
M, k be 0.001, θ 1 for 220 °~(220 ° of+α).The axial length of runner exit 8 is 600 μm.
Mixing liquid at the uniform velocity injects micro-mixer from three flow channel entry points respectively under pressure-driven, and entrance channel 2 injects
Ethanol solution, in order to ensure that different component fluid equivalent injects runner, the water etc. quality injects from flow channel entry point 1.Now ethanol
Solution enters from the vertical counter current flow in sprue both sides.By 4 mixed cells of the blender, from runner exit after being sufficiently mixed
8 outflows.
Claims (5)
1. a kind of cross micro-mixer of axial symmetry log spiral, including closely sealed cover plate together（3）And matrix（9）, its
It is characterized in：Cover plate（3）And matrix（9）Between be provided with the cross runner for being sequentially connected and connecing（10）, a contracted channel（4）
With several mixed cells, each mixed cell is by a narrow straight channel being connected（5）, a log spiral runner
（6）And it is placed on log spiral runner（6）In a log spiral baffle plate（7）Constitute；Several mixed cell strings
Contracted channel is connected to after connecing（4）And runner exit（8）Between；Cross runner（10）Outlet connection contracted channel（4）Entrance,
Contracted channel（4）Narrow straight channel in outlet first mixed cell of connection（5）Entrance, last log spiral runner
（6）Outlet connecting passage outlet（8）And the exit width and runner exit（8）Width it is identical, remaining log spiral runner
（6）Outlet with narrow straight channel（5）Width it is identical；Contracted channel（4）With the center of mixed cell in a central shaft
On, log spiral runner（6）With log spiral baffle plate（7）All on substantially symmetrical about its central axis；Log spiral baffle plate（7）It is recessed
Face faces the log spiral runner at place（6）Entrance, log spiral baffle plate（7）Edges at two ends and log spiral stream
Road（6）Inwall between have gap；Log spiral runner（6）Contour line by two on the right of distribution substantially symmetrical about its central axis
Number helix is constituted, and log spiral equation is, log spiral starting point is positioned at logarithmic spiral
Line baffle plate（7）The apex of concave surface one end, wrap angle sigma is 135 °, and e is the truth of a matter of natural logrithm function, and its value is 2.71828,Be 20 μm, k be 0.001, θ 1 for 220 °~(220 ° of+α)；
Log spiral baffle plate（7）Contour line be that two two log spirals on distribution substantially symmetrical about its central axis are constituted, its
Log spiral equation is, its starting point is the log spiral runner at place（6）Entrance center
Point, cornerite β is 30 °,Be 15 μm, k be 0.001, θ 2 for 270 °~(270 ° of+β).
2. a kind of cross micro-mixer of axial symmetry log spiral according to claim 1, it is characterized in that：Cross runner
（10）One sprue entrance of upper arrangement（1）With two secondary channels entrances（2）, two centers of secondary channels are conllinear, sprue and
Two secondary channels are mutually perpendicular to, cross runner（10）Sprue center on center shaft, cross runner（10）Main flow
Road outlet connection contracted channel（4）Import.
3. a kind of cross micro-mixer of axial symmetry log spiral according to claim 2, it is characterized in that：Cross runner
（10）Sprue entrance width be D1,200 μm<D1<400 μm, D1 is equal to cross runner（10）Secondary channels import it is wide
Spend the twice of D2；The length L1=2.5 of sprue import × (D1), the length L3 of secondary channels import is equal to L1, secondary channels and contraction
Runner（4）Between beeline L2=2 × (D1)；Narrow straight channel（5）Axial length L 4=(D1)/2, width D 3=
(D1)/4。
4. a kind of cross micro-mixer of axial symmetry log spiral according to claim 3, it is characterized in that：Log spiral
Runner（6）The starting point of the log spiral of contour line is D1/3 apart from the vertical range of central shaft, apart from adjacent logarithmic spiral
Line runner（6）Its maximum width axial distance L5=2.5 × (D1).
5. a kind of cross micro-mixer of axial symmetry log spiral according to claim 3, it is characterized in that：Contracted channel
（4）Throat width, log spiral runner（6）Breadth Maximum and last log spiral runner（6）Exit width
It is D1.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510503838.7A CN105148781B (en) | 2015-08-17 | 2015-08-17 | A kind of cross micro-mixer of axial symmetry log spiral |
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| CN201510503838.7A CN105148781B (en) | 2015-08-17 | 2015-08-17 | A kind of cross micro-mixer of axial symmetry log spiral |
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| CN105148781A CN105148781A (en) | 2015-12-16 |
| CN105148781B true CN105148781B (en) | 2017-06-27 |
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| CN111446221B (en) * | 2020-05-08 | 2022-03-08 | 西安交通大学 | Low-flow-resistance chip embedded array micro-jet radiator and manufacturing method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1835789A (en) * | 2003-06-11 | 2006-09-20 | 科学、技术与研究机构 | Micromixer apparatus and methods of using same |
| CN102202774A (en) * | 2008-09-29 | 2011-09-28 | 康宁股份有限公司 | Multiple flow path microreactor design |
| CN103638853A (en) * | 2013-11-11 | 2014-03-19 | 江苏大学 | S-type passive micro-mixer |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090291505A1 (en) * | 2006-07-14 | 2009-11-26 | Roche Molecular System, Inc. | Analytical Device for Thermally Treating a Fluid and/or Monitoring a Property Thereof |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1835789A (en) * | 2003-06-11 | 2006-09-20 | 科学、技术与研究机构 | Micromixer apparatus and methods of using same |
| CN102202774A (en) * | 2008-09-29 | 2011-09-28 | 康宁股份有限公司 | Multiple flow path microreactor design |
| CN103638853A (en) * | 2013-11-11 | 2014-03-19 | 江苏大学 | S-type passive micro-mixer |
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