CN105147926A - Compound artificial leather and preparing method thereof - Google Patents
Compound artificial leather and preparing method thereof Download PDFInfo
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- CN105147926A CN105147926A CN201510712827.XA CN201510712827A CN105147926A CN 105147926 A CN105147926 A CN 105147926A CN 201510712827 A CN201510712827 A CN 201510712827A CN 105147926 A CN105147926 A CN 105147926A
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Abstract
The invention belongs to the technical field of drugs for external use, and particularly relates to compound artificial leather and a preparing method thereof. The compound artificial leather is prepared from sesame oil, borneol, musk, saffron crocus, dragon blood, cutch, rheum officinale, radix angelicae, coptis chinensis, polygonum cuspidatum, radix rehmanniae, sanguisorba officinalis, dandelion, lithospermum and angelica sinensis. The compound artificial leather is mainly used for treating burns and scalds, and timely treatment of burns and scalds under the level of deep three degree is free of permeation and does not need fluid infusion; infection is avoided, and skin-grafting is not needed; pains can not be caused, and anesthesia is not needed; scars can not be generated, and an operation is not needed; treatment time is short, and a wound can be cured quickly. The compound artificial leather can also be used for treating various of skin traumas, chemical injuries and persistent and incurable wounds. Equipment adopted in the preparing method is simple, operation is easy, and production cost is low.
Description
Technical field
The invention belongs to the technical field of medicine for external use, be specifically related to a kind of compound recipe artificial skin and preparation method thereof.
Background technology
Burn and scald is a kind of acute injury caused because boiling water, steam, flame, chemical substance etc. directly act on body surface organization.Burn and scald is generally divided into three degree: I degree of burn, only shows as red swelling of the skin, scorching hot, pain, does not have vesicle, do not stay cicatrix; II degree of burn, there is vesicle in skin, local is red and swollen, and sharp ache, treats general without large cicatrix in time; III degree of burn, the most seriously, infringement is dark, and skin is burned black, downright bad, and skeleton and blood vessel expose, and charrin's disease septicemia very easily occurs dead.
Owing to there is wound pain in burn and scald treatment, necrosis progrediens, easy infection, the difficult problems such as cicatrix healing, burned patient often can be subject to the torment of pain of patients changing dressing, current Therapeutic Method is adopted to there will be cicatrix, the wounds such as adhesion torment, if burned patient is treated not in time, the state of an illness is protracted course of disease often, some patients can change severe burn and scald into from slight burn and scald, very large misery can be brought to patient, also can scar disabled etc., and western modern medicine treatment burn and scald can advise skin-grafting mostly, curative effect is low, take effect slow, medical expense is expensive simultaneously, economic overdraw is even gone bankrupt or broke.
Modern medical therapy burn and scald is the most thorny: the body fluid of hindering on face runs off in a large number, causes the suffer a shock dysfunction of each organ of secondary whole body of patient even to cause death.By patient injury size, doctor trained in Western medicine generally after 36/48/72 hour could the control of medicine and patient the person natural antibody cooperation under stop completely penetrating fluid run off, and penetrating fluid can be stopped, be the key subjects that success saves burn and scald severe case life.
Modern dark II degree of burn therapeutic treatment large area, light degree Ⅲ burn and scald can leave over cicatrix, and it is impossible for leaving over without cicatrix.Adopt western medical treatment often can occur I degree by usual rule and become II degree, II degree change III degree ... situation, cause patient deeply by shock close and infect close torment.
Convalescent period under western medical treatment is generally: I degree of empyrosis wound surface agglutination: resolution of symptoms in 2 ~ 3 days, and recovery from illness in 3 ~ 5 days, desquamation, without cicatrix.Light degree Ⅱ empyrosis wound surface agglutination: as without infecting recovery from illness in 11 ~ 14 days, do not stay cicatrix.Dark II degree of empyrosis wound surface agglutination: recovery from illness in general 21 ~ 28 days, can leave over cicatrix.III degree of empyrosis wound surface agglutination: eschar came off in 21 ~ 28 days, heals after need making skin graft, leaves over cicatrix, deformity.
Current clinically conventional have moist expose burn ointment, JINGWANHONG etc., and basic hospital is especially more with moist expose burn ointment application, but above medicine effect in controlling traumatic infection etc. is not ideal enough, often can cause side effect.
Summary of the invention
The object of the invention is to ooze out for current treatment penetrating fluid not easily stop; There will be the wound such as cicatrix, adhesion to torment; Often can be subject to the torment of pain of patients changing dressing; Somewhat expensive; The dissatisfactory problems of aspect effect such as traumatic infection, and provide a kind of compound recipe artificial skin and preparation method thereof, this compound recipe artificial skin cures mainly burn and scald, to the nothing infiltration in the process for the treatment of in time of the burn and scald below deep third degree, without fluid infusion; Without infecting, need not make skin graft; Without pain, need not anaesthetize; Without cicatrix, without hands art; Treatment time is short, recovers from injury rapidly.Various traumatic injury of skin, chemical injury and obstinate wound can also be treated simultaneously.Preparation method device therefor is simple, and easy to operate, production cost is low.
Technical scheme of the present invention is: a kind of compound recipe artificial skin, comprises following raw material: Oleum sesami, Borneolum Syntheticum, Moschus, Stigma Croci, Sanguis Draxonis, catechu, Radix Et Rhizoma Rhei, the Radix Angelicae Dahuricae, Rhizoma Coptidis, Rhizoma Polygoni Cuspidati, the Radix Rehmanniae, Radix Sanguisorbae, Herba Taraxaci, Radix Arnebiae (Radix Lithospermi), Radix Angelicae Sinensis.
Described compound recipe artificial skin, comprise the raw material of following weight portion: Oleum sesami 12 ~ 19 parts, Borneolum Syntheticum 12 ~ 17 parts, 0.06 ~ 0.10 part, Moschus, Stigma Croci 15 ~ 23 parts, Sanguis Draxonis 45 ~ 55 parts, 65 ~ 75 parts, catechu, Radix Et Rhizoma Rhei 48 ~ 58 parts, the Radix Angelicae Dahuricae 29 ~ 37 parts, Rhizoma Coptidis 40 ~ 48 parts, Rhizoma Polygoni Cuspidati 28 ~ 34 parts, 14 ~ 21 parts, the Radix Rehmanniae, Radix Sanguisorbae 37 ~ 43 parts, Herba Taraxaci 18 ~ 23 parts, Radix Arnebiae (Radix Lithospermi) 10 ~ 15 parts, Radix Angelicae Sinensis 21 ~ 27 parts.
Described compound recipe artificial skin, comprise the raw material of following weight portion: Oleum sesami 14 ~ 18 parts, Borneolum Syntheticum 13 ~ 16 parts, 0.07 ~ 0.09 part, Moschus, Stigma Croci 18 ~ 21 parts, Sanguis Draxonis 48 ~ 53 parts, 68 ~ 73 parts, catechu, Radix Et Rhizoma Rhei 52 ~ 56 parts, the Radix Angelicae Dahuricae 31 ~ 35 parts, Rhizoma Coptidis 42 ~ 46 parts, Rhizoma Polygoni Cuspidati 30 ~ 33 parts, 17 ~ 19 parts, the Radix Rehmanniae, Radix Sanguisorbae 39 ~ 41 parts, Herba Taraxaci 20 ~ 22 parts, Radix Arnebiae (Radix Lithospermi) 12 ~ 14 parts, Radix Angelicae Sinensis 23 ~ 26 parts.
Described compound recipe artificial skin, comprise the raw material of following weight portion: Oleum sesami 16 parts, Borneolum Syntheticum 15 parts, 0.08 part, Moschus, Stigma Croci 19 parts, Sanguis Draxonis 51 parts, 71 parts, catechu, Radix Et Rhizoma Rhei 55 parts, the Radix Angelicae Dahuricae 33 parts, Rhizoma Coptidis 44 parts, Rhizoma Polygoni Cuspidati 32 parts, 18 parts, the Radix Rehmanniae, Radix Sanguisorbae 40 parts, Herba Taraxaci 21 parts, Radix Arnebiae (Radix Lithospermi) 13 parts, Radix Angelicae Sinensis 25 parts.
Described compound recipe artificial skin, comprise the raw material of following weight portion: Oleum sesami 12 parts, Borneolum Syntheticum 12 parts, 0.06 part, Moschus, Stigma Croci 15 parts, Sanguis Draxonis 45 parts, 65 parts, catechu, Radix Et Rhizoma Rhei 48 parts, the Radix Angelicae Dahuricae 29 parts, Rhizoma Coptidis 40 parts, Rhizoma Polygoni Cuspidati 28 parts, 14 parts, the Radix Rehmanniae, Radix Sanguisorbae 37 parts, Herba Taraxaci 18 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Radix Angelicae Sinensis 21 parts.
Described compound recipe artificial skin, comprise the raw material of following weight portion: Oleum sesami 19 parts, Borneolum Syntheticum 17 parts, 0.10 part, Moschus, Stigma Croci 23 parts, Sanguis Draxonis 55 parts, 75 parts, catechu, Radix Et Rhizoma Rhei 58 parts, the Radix Angelicae Dahuricae 37 parts, Rhizoma Coptidis 48 parts, Rhizoma Polygoni Cuspidati 34 parts, 21 parts, the Radix Rehmanniae, Radix Sanguisorbae 43 parts, Herba Taraxaci 23 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, Radix Angelicae Sinensis 27 parts.
Described compound recipe artificial skin, comprise the raw material of following weight portion: Oleum sesami 14 parts, Borneolum Syntheticum 13 parts, 0.07 part, Moschus, Stigma Croci 18 parts, Sanguis Draxonis 48 parts, 68 parts, catechu, Radix Et Rhizoma Rhei 52 parts, the Radix Angelicae Dahuricae 31 parts, Rhizoma Coptidis 42 parts, Rhizoma Polygoni Cuspidati 30 parts, 17 parts, the Radix Rehmanniae, Radix Sanguisorbae 39 parts, Herba Taraxaci 20 parts, Radix Arnebiae (Radix Lithospermi) 12 parts, Radix Angelicae Sinensis 23 parts.
Described compound recipe artificial skin, comprise the raw material of following weight portion: Oleum sesami 18 parts, Borneolum Syntheticum 16 parts, 0.09 part, Moschus, Stigma Croci 21 parts, Sanguis Draxonis 53 parts, 73 parts, catechu, Radix Et Rhizoma Rhei 56 parts, the Radix Angelicae Dahuricae 35 parts, Rhizoma Coptidis 46 parts, Rhizoma Polygoni Cuspidati 33 parts, 19 parts, the Radix Rehmanniae, Radix Sanguisorbae 41 parts, Herba Taraxaci 22 parts, Radix Arnebiae (Radix Lithospermi) 14 parts, Radix Angelicae Sinensis 26 parts.
A preparation method for described compound recipe artificial skin, comprises pulverizing, soak extraction and preparation, soaks 6 months; Preparation adopts Cera Flava as excipient.
Beneficial effect of the present invention is: compound recipe artificial skin of the present invention comprises following raw material: Oleum sesami, Borneolum Syntheticum, Moschus, Stigma Croci, Sanguis Draxonis, catechu, Radix Et Rhizoma Rhei, the Radix Angelicae Dahuricae, Rhizoma Coptidis, Rhizoma Polygoni Cuspidati, the Radix Rehmanniae, Radix Sanguisorbae, Herba Taraxaci, Radix Arnebiae (Radix Lithospermi), Radix Angelicae Sinensis.
Oleum sesami: rich in vitamin E and linolenic acid, wherein vitamin E has antioxidation, can maintain integrity and the normal function of cell membrane, has and promotes fissional effect; The unsaturated fatty acids such as the linoleic acid in Oleum sesami, Palmic acid are easily absorbed by the body.Oleum sesami has antiinflammatory, itching-relieving action.
Borneolum Syntheticum: acrid in the mouth is bitter, cool in nature; Enter the heart, lung meridian.Logical all keys, loose stagnated fire, reducing swelling and alleviating pain.Boiling hot, burn can be controlled.Asthenia of qi and blood person is forbidden.
Moschus: acrid in the mouth, warm in nature; GUIXIN, spleen channel.There is promoting blood circulation to restore menstrual flow, effect of pain relieving.External can be eased pain, be subsided a swelling.
Stigma Croci: sweet in the mouth, property is put down, nontoxic.Have calmness, invigorate blood circulation, spasmolysis, can blood circulation promoting and blood stasis dispelling, removing pathogenic heat from blood and toxic substance from the body, resolving stagnation for tranquilization, pain relieving.Can be used as calmness, carminative.Cure mainly injury from falling down.
Sanguis Draxonis: sweet in the mouth; Salty; Property is put down; Mild toxicity.GUIXIN warp; Liver Channel.There is dissipating blood stasis analgesic therapy; Hemostasis; Effect of promoting tissue regeneration and ulcer healing.Cure mainly traumatic injury; Continuous bleeding due to traumatic injury.
Catechu: bitter in the mouth, puckery, cold nature.Return lung meridian.There is effect of removing dampness, promoting tissue regeneration and ulcer healing.The pain of injury is flutterred, traumatic hemorrhage for falling.
Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature.Return spleen, stomach, large intestine, liver, pericardium channel.There is cooling blood and removing stasis hemostasis, effect of heat-clearing and toxic substances removing.External treatment traumatic injury; Burn due to hot liquid or fire.Deficiency and coldness of spleen and stomach, blood deficiency gas weak person are cautious use of.
The Radix Angelicae Dahuricae: warm in nature, acrid in the mouth, gas fragrance, micro-hardship.Enter lung, spleen, stomach warp.There is evacuation of pus of invigorating blood circulation, granulation promoting, analgesic efficacy.For evacuation of pus of dissipating.
Rhizoma Coptidis: bitter in the mouth, cold in nature, nontoxic.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.There is effect of heat-clearing and toxic substances removing.
Rhizoma Polygoni Cuspidati: mildly bitter flavor, cold nature.Return liver, gallbladder, lung meridian.There is heat-clearing and toxic substances removing, effect of dissipating blood stasis analgesic therapy.For burn due to hot liquid or fire, injury from falling down, can play antibacterial, anastalsis.
The Radix Rehmanniae: cold in nature, has effect of heat clearing away, removing blood stasis with potent drugs, tissue regeneration promoting, pain relieving, cooling blood for hemostasis; Because of cold in nature and stagnant, insufficiency of the spleen loose stool person, should not use.
Radix Sanguisorbae: bitter in the mouth acid; Cold in nature; Nontoxic.Return liver; Lung; Kidney; Large intestine channel.There is cooling blood for hemostasis, heat-clearing and toxic substances removing, effect of detumescence sore.The effect of convergence, the hemostasis of antibacterial, antiinflammatory can be played.
Herba Taraxaci: property is put down; Sweet and slightly bitter taste.There is the effect of heat-clearing and toxic substances removing, antipyretic removing heat from blood, dispersing swelling and dissipating binds.
Radix Arnebiae (Radix Lithospermi): cold in nature is sweet in the mouth, salty.GUIXIN, Liver Channel.There is removing heat from blood, hemostasis, effect of removing toxic substances rash.For burn due to hot liquid or fire, burn.But gastrointestinal is weak, stool lingering diarrhea person is all forbidden.
Radix Angelicae Sinensis: sweet in the mouth; Pungent; Warm in nature.Return liver; The heart; Spleen channel.Have and enrich blood; Invigorate blood circulation; Analgesic efficacy; Bacteriostasis can be played.Cure mainly ulcer sores, injury from falling down.
In compound recipe artificial skin prescription of the present invention, first reuse catechu, with the effect of row promoting tissue regeneration and ulcer healing; Sanguis Draxonis and catechu share, and the cooperation Radix Angelicae Dahuricae, Radix Sanguisorbae play the effect of dissipating blood stasis analgesic therapy, hemostasis, promoting tissue regeneration and ulcer healing altogether, help with Rhizoma Polygoni Cuspidati, Oleum sesami and Radix Angelicae Sinensis, strengthen antiinflammatory, antibacterial and itching-relieving action; Stigma Croci, Sanguis Draxonis share, and coordinate the power multiplication of Borneolum Syntheticum and Moschus pain relieving; Radix Et Rhizoma Rhei, the Radix Angelicae Dahuricae and Rhizoma Coptidis are share, and are equipped with Herba Taraxaci, Stigma Croci, Rhizoma Polygoni Cuspidati and Radix Sanguisorbae, and the power benefit of heat-clearing and toxic substances removing is evident; The Radix Rehmanniae and Radix Sanguisorbae are share, and coordinate effect multiplication of Radix Arnebiae (Radix Lithospermi) cooling blood for hemostasis; Help with effect of Borneolum Syntheticum, Herba Taraxaci and the detumescence of Radix Sanguisorbae row simultaneously.All medicines are harmonious, and play promoting tissue regeneration and ulcer healing, antibacterial pain relieving altogether, prevent penetrating fluid from oozing out and the merit of heat-clearing and toxic substances removing.
Adopt the combination matching mode of raw material described in this prescription simultaneously, mutual cooperative compensating between all taste medicines, the object for the treatment of burn and scald can not only be reached, and overcome the taboo problem that Borneolum Syntheticum and Radix Et Rhizoma Rhei forbid for asthenia of qi and blood person, also solve the problem that the insufficiency of the spleen loose stool person of the Radix Rehmanniae should not use, expand the range of application of this artificial skin.
Described compound recipe artificial skin is adopted never to occur over the course for the treatment of to infect and putrefactive phenomenon; Can not cicatrix be left over, can not stick together; Without the need to making skin graft; Can effectively prevent oozing out of penetrating fluid, within 20 ~ 30 seconds, can penetrating fluid be stopped; Promote wound face quickly-healing; Within 30 ~ 60 seconds, stop burn and scald severe pain, process of changing dressings is without pain; Healing time is fast, and less than three degree healing times only need 3 ~ 10 days; Therapeutic effect is obvious, treats preventing from scar in time for less than three degree; Be easy to checking, there is not the course for the treatment of and the problem such as repeatedly of common Chinese; Save treatment cost, less than three degree alternative doctor trained in Western medicine dermatoplastic treatments, patient home exempts from huge medical care expenses burden.
This compound recipe artificial skin has following features:
(1) very first time stops body fluid pervious loss, the generation of nothing shock and each organ complications of whole body; (2) hinder face and air exclusion, traumatic infection can not occur; (3) treat whole process not form a scab, absolute no pain of changing dressings; (4) to dark II degree, light degree Ⅲ burn do not leave over cicatrix; (5) treatment time is short, recovers from injury rapidly: the very first time after the drug of topical application, namely the efficacy of a drug starts to go deep into skin, promotes that Skin Cell divides rapidly and growth, within 3-5 days, can generate the tender skin as baby.Therefore, the burn below deep third degree, generally can fully recover at 7-10 days.And western medical treatment, general 3-7 talent, to the absorption of edema phase, 21-28 days is the molten crust phase.
Use this compound recipe artificial skin after the medicine-feeding of patient injury, can form the medicine film of thin layer on wounds, medicine film, just as an artificial skin, prevents body water from evaporating, prevent the infection of the antibacterial in air and the antibacterial on skin surface attachment, play the partial function of human body skin.
Clinical trial is carried out to compound recipe artificial skin of the present invention below as follows:
1, physical data: 200 routine patients are clinical burned patient of seeing and treating patients, adopts randomized, double-blind principle to be divided into two groups, treatment group 100 example, man 60 example, female 40 example, 9 months ~ 81 years old age, wherein there are 11 examples in male 60 examples for insufficiency of the spleen loose stool person, have 9 examples in female 40 example for asthenia of qi and blood person.
Matched group 100 example, man 60 example, female 40 example, 9 months ~ 80 years old age.Two groups of physical data comparing differences, without statistical discrepancy, have comparability.
2. burn surface area, depth profile, in table 1.
Table 1
3. fire victim's traumatogenic reason situation, asks for an interview table 2.
Table 2
| Group | Hot water is scalded | Flame burn | Hot soup is scalded | Blast burn | Deep fat is scalded | Other |
| Treatment group | 31 | 16 | 26 | 5 | 19 | 3 |
| Matched group | 31 | 15 | 26 | 5 | 20 | 3 |
4. clinical indices is observed: (1) wound healing effect; (2) analgesic effect in therapeutic process; (3) traumatic infection degree; (4) cicatrix incidence rate; (5) whether untoward reaction is had in medication process.
5. result
(1) wound healing effect, asks for an interview table 3.
Table 3
| Group | Case load | Curative day |
| Treatment group light degree Ⅱ | 72 | 3 ~ 6 days |
| Matched group light degree Ⅱ | 69 | 17 ~ 21 days |
| Dark II degree for the treatment of group | 28 | 7 ~ 10 days |
| Dark II degree of matched group | 31 | 24 ~ 32 days |
(2) analgesic effect in therapeutic process: in the routine patient for the treatment of group 100, the patient of 21% has stopped empyrosis wound surface severe pain in 30 ~ 36 seconds after medication, and without pain in follow-up process of changing dressings; The patient of 63% has stopped empyrosis wound surface severe pain in 42 ~ 47 seconds after medication, and without pain in follow-up process of changing dressings; The patient of another 16% has stopped empyrosis wound surface severe pain in 55 ~ 60 seconds after medication, and also without pain in follow-up process of changing dressings.
In the routine patient of matched group 100,41.3% wound pain alleviation in 20 minutes after medication, has pain in follow-up process of changing dressings; 34.3% wound pain alleviation in 40 minutes after medication, has strong pain in follow-up process of changing dressings; Another 24.4% after medication in 50 minutes wound pain without alleviating, need analgesic drug product pain relieving, in follow-up process of changing dressings, have pain unbearably.
(3) traumatic infection degree: in the routine patient for the treatment of group 100, none example infects; 41.5% edge of wound inflammatory infiltration reaction in the routine patient of matched group 100; Empyema under 39.7% crust; 16.3% cambium necrosis or growth retardation; 2.5% high heat.
(4) cicatrix incidence rate: in the routine patient for the treatment of group 100, none example has cicatrix to occur; In the routine patient of matched group 100,58.2% has cicatrix to occur, and wherein the cicatrix area of 37.8% is the cicatrix area of 4.75%, 20.4% is 6.07%.
(5) whether untoward reaction is had in medication process: in treatment group, man 11 routine insufficiency of the spleen loose stool persons and the routine asthenia of qi and blood person of female 9 all do not occur malaise symptoms.
In sum, compound recipe artificial skin of the present invention can stop body fluid pervious rapidly, without fluid infusion, therefore can alleviate the medical care expenses burden of patient in a large number.It can infection, relieve the pain fast, recover fast, reduce and prevent cicatrix and adhesion from producing.The change adopting compound recipe artificial skin treatment patient to occur is three degree and was once becoming two degree, two degree changes, makes patient safety leave on pass.
Detailed description of the invention
Below by embodiment, the present invention will be described in detail.
Embodiment 1
Described compound recipe artificial skin, comprise the raw material of following weight: Oleum sesami 16g, Borneolum Syntheticum 15g, Moschus 0.08g, Stigma Croci 19g, Sanguis Draxonis 51g, catechu 71g, Radix Et Rhizoma Rhei 55g, Radix Angelicae Dahuricae 33g, Rhizoma Coptidis 44g, Rhizoma Polygoni Cuspidati 32g, Radix Rehmanniae 18g, Radix Sanguisorbae 40g, Herba Taraxaci 21g, Radix Arnebiae (Radix Lithospermi) 13g, Radix Angelicae Sinensis 25g.
Matched group: the compound recipe artificial skin of employing, comprise the raw material of following weight: Oleum sesami 10g, Borneolum Syntheticum 20g, Moschus 0.04g, Stigma Croci 26g, Sanguis Draxonis 36g, catechu 51g, Radix Et Rhizoma Rhei 63g, Radix Angelicae Dahuricae 23g, Rhizoma Coptidis 50g, Rhizoma Polygoni Cuspidati 22g, Radix Rehmanniae 18g, Radix Sanguisorbae 40g, Herba Taraxaci 11g, Radix Arnebiae (Radix Lithospermi) 23g, Radix Angelicae Sinensis 31g.
This compound recipe artificial skin is the method for employing heat medicine-feeding, Chinese medicine is first heated to 260 DEG C and makes the rear use of medicine boiling, be then cooled to 70-80C °, then add medicine at wound to patient.Secondary not only can not be caused to scald, and can effectively promote wound surface quickly-healing, ooze out at preventing humor simultaneously, infection, relieve the pain, substitute skin grafting etc. in performance very outstanding.
Zhang, female, 9 months large, and the right hand is by by hot gruel rats after severe scald burn.Through hospital, the inspection of burn and scald traumatology is made a definite diagnosis, and girl baby's right hand two to three degree is scalded.
Making a definite diagnosis and time limit of western medical treatment burn and scald according to hospital, the scald of this girl baby needs could fully recover for more than 1 month.And, because the immunity of baby own is lower, there is the problems such as easy infection, easily shock.In resistance to pain, the obvious defectiveness of baby, cries bitterly and incessantly can cause shock and death by suffocation.In nutrition intake, baby is by scalding ache influence, and obviously without appetite, growth recovery desired nutritional material only has by doctor trained in Western medicine transfusion solution.
Girl baby sees and treat patients after scalding 4 hours, girl baby does not have an injection and does not take medicine, only use compound recipe artificial skin treatment described in embodiment 1, curative effect is as follows: stop wound pain in medication after 31 ~ 37 seconds, girl baby treats recovery from illness in 5 days, and period changes dressings 6 times, in the process of changing dressings of 6 times, there is no pain, change dressings all quieter at every turn, do not wail without ceasing.But compound recipe artificial skin described in employing matched group, treat 25 talentes and be almost recovered, in process of changing dressings, Zhang wails without ceasing, disorderly dynamic from head to foot.
As can be seen here, for same patient, even if adopt identical raw material composition, but the weight changing wherein a few taste medicine brings a great difference to therapeutic effect, not only collaborative combined effect mutually between each taste medicine in this compound recipe artificial skin can be drawn, simultaneously indivisible organic whole between the weight portion that adopts of each taste medicine and each taste medicine, must both satisfied optimum efficiencies that just can reach treatment simultaneously.
Treatment analysis for adopting compound recipe artificial skin described in embodiment 1:
1, advantage
Girl baby is in growth promoter period, and Organism Growth cell division enlivens;
2, shortcoming
Resistance to pain is poor, and anti-infection ability is poor, and skin repair nutrition intake is not enough.
3, compound recipe artificial skin treatment advantage
(1) about relieving the pain: within 31 ~ 37 seconds, relieve the pain.Therefore girl baby is after the drug of topical application, can quiet down in one's arms father or mother at once.
(2) ooze out about body fluid: compound recipe artificial skin stops penetrating fluid in 22 ~ 25 seconds, therefore, do not need fluid-supplement therapy burn and scald, because there is not the fluid infusion time, so the treatment phase can be shortened.
(3) about infection problems: compound recipe artificial skin is heated to more than 260 degrees Celsius in use, the antibacterial of medical surfaces attachment is killed.Take heat medicine-feeding during medicine-feeding, kill the antibacterial that wound circumference is grown.Hinder patient the medicine film that face forms thin layer after the artificial feverish skin medicine-feeding of compound recipe, can effectively prevent antibacterial intrusion.Medicine itself also has powerful bactericidal effect.Therefore can effectively protect from infection, patient is in and treats, and without the need to bio-clean treatment unit, and doctor trained in Western medicine coordinates antiinflammatory.
Distance child recovery from illness 4 months, does not leave any cicatrix (generation according to the said scar tissue of expert mainly generated at 3-6 month).
Embodiment 2
Described compound recipe artificial skin, comprise the raw material of following weight: Oleum sesami 12g, Borneolum Syntheticum 12g, Moschus 0.06g, Stigma Croci 15g, Sanguis Draxonis 45g, catechu 65g, Radix Et Rhizoma Rhei 48g, Radix Angelicae Dahuricae 29g, Rhizoma Coptidis 40g, Rhizoma Polygoni Cuspidati 28g, Radix Rehmanniae 14g, Radix Sanguisorbae 37g, Herba Taraxaci 18g, Radix Arnebiae (Radix Lithospermi) 10g, Radix Angelicae Sinensis 21g.
This compound recipe artificial skin is the method for employing heat medicine-feeding, Chinese medicine is first heated to 260 DEG C and makes the rear use of medicine boiling, be then cooled to 70-80C °, then add medicine at wound to patient.Secondary not only can not be caused to scald, and can effectively promote wound surface quickly-healing, ooze out at preventing humor simultaneously, infection, relieve the pain, substitute skin grafting etc. in performance very outstanding.
Money so-and-so, man, 34 years old, accidentally one pot of deep fat is knocked on ground, meet with deep fat scald.This patient is also a neural sensitivity type people.The hot oil temperature of deep-fried twisted dough sticks is more than 200 degrees Celsius.Time of 10 days is recovered experienced by whole face of hindering, and wound face place does not generate any scar tissue, does not leave any cicatrix.The following characteristics of this therapeutic process checking compound recipe artificial skin:
1, ease pain rapidly, change dressings without pain.
2, treat whole process not form a scab, there is no scar.
3, scalded more than boiled water scald much serious by deep fat, treatment convalescent period is long.
If 4, patient can strictly aviod certain food, be then conducive to the property of medicine and play, skin histology is repaired as early as possible.
5, blood oozing from the wound surface and do not form a scab be compound recipe artificial skin treatment unique phenomena.Oozing of blood means that injury blood vessel activates, and regenerative cell can obtain sufficient nutriment to recover wound surface.Therefore, in general having one's hair waved situation, as long as see blood oozing from the wound surface, then treat and will fully recover for 3-5 days.By observing the wound surface recovered, wound surface heals 67 day time completely, although there is pigmentation, without any scar hyperplasia sign.
Embodiment 3
Described compound recipe artificial skin, comprise the raw material of following weight: Oleum sesami 19g, Borneolum Syntheticum 17g, Moschus 0.10g, Stigma Croci 23g, Sanguis Draxonis 55g, catechu 75g, Radix Et Rhizoma Rhei 58g, Radix Angelicae Dahuricae 37g, Rhizoma Coptidis 48g, Rhizoma Polygoni Cuspidati 34g, Radix Rehmanniae 21g, Radix Sanguisorbae 43g, Herba Taraxaci 23g, Radix Arnebiae (Radix Lithospermi) 15g, Radix Angelicae Sinensis 27g.
Matched group: compound recipe artificial skin described in the compound recipe artificial skin of employing and embodiment 1, comprise the raw material of following weight: Oleum sesami 16g, Borneolum Syntheticum 15g, Moschus 0.08g, Stigma Croci 19g, Sanguis Draxonis 51g, catechu 71g, Radix Et Rhizoma Rhei 55g, Radix Angelicae Dahuricae 33g, Rhizoma Coptidis 44g, Rhizoma Polygoni Cuspidati 32g, Radix Rehmanniae 18g, Radix Sanguisorbae 40g, Herba Taraxaci 21g, Radix Arnebiae (Radix Lithospermi) 13g, Radix Angelicae Sinensis 25g.
This compound recipe artificial skin is the method for employing heat medicine-feeding, Chinese medicine is first heated to 260 DEG C and makes the rear use of medicine boiling, be then cooled to 70-80C °, then add medicine at wound to patient.Secondary not only can not be caused to scald, and can effectively promote wound surface quickly-healing, ooze out at preventing humor simultaneously, infection, relieve the pain, substitute skin grafting etc. in performance very outstanding.
Close so-and-so, man, 81 one full year of life, build is very thin, substantially fat-free layer.The soup boiled for the treatment of different things alike all waters on old man's right forearm and right hand the back of the hand, dark two degree ~ tri-degree scalds of tentative diagnosis.Because old man is older, stratum germinativum epidermidis Growth of Cells and splitting ability poor, recover slow.Old man's build is very thin simultaneously, substantially fat-free layer, can not provide sufficient nutrient substance for cell regeneration.Treatment difficulty is large.Adopt compound recipe artificial skin described in embodiment 3 to the therapeutic effect of the old man that III degree is scalded, patient by 16 medicine-feeding treatments, hindered face and substantially heals in 10 days.The places such as old man's arm, hands do not leave over cicatrix sign above.And stop wound pain in medication after 47 ~ 55 seconds, in the process of changing dressings of whole treatment, there is no pain.But compound recipe artificial skin described in employing matched group, just stops wound pain in medication after 60 seconds, treat 10 talentes and be almost recovered.
As can be seen here, for different patient, even if adopt same prescription, raw material and raw material weight are all consistent, but therapeutic effect but brings a great difference, can show that the weight portion between each taste medicine described in this compound recipe artificial skin and each taste medicine is selected and unconventional selection, non-obvious, need to comprise patient condition, patient age and different skin character in conjunction with many factors and just can draw described prescription.
Embodiment 4
Described compound recipe artificial skin, comprise the raw material of following weight: Oleum sesami 14g, Borneolum Syntheticum 13g, Moschus 0.07g, Stigma Croci 18g, Sanguis Draxonis 48g, catechu 68g, Radix Et Rhizoma Rhei 52g, Radix Angelicae Dahuricae 31g, Rhizoma Coptidis 42g, Rhizoma Polygoni Cuspidati 30g, Radix Rehmanniae 17g, Radix Sanguisorbae 39g, Herba Taraxaci 20g, Radix Arnebiae (Radix Lithospermi) 12g, Radix Angelicae Sinensis 23g.
This compound recipe artificial skin is the method for employing heat medicine-feeding, Chinese medicine is first heated to 260 DEG C and makes the rear use of medicine boiling, be then cooled to 70-80C °, then add medicine at wound to patient.Secondary not only can not be caused to scald, and can effectively promote wound surface quickly-healing, ooze out at preventing humor simultaneously, infection, relieve the pain, substitute skin grafting etc. in performance very outstanding.
Embodiment 5
Described compound recipe artificial skin, comprise the raw material of following weight: Oleum sesami 18g, Borneolum Syntheticum 16g, Moschus 0.09g, Stigma Croci 21g, Sanguis Draxonis 53g, catechu 73g, Radix Et Rhizoma Rhei 56g, Radix Angelicae Dahuricae 35g, Rhizoma Coptidis 46g, Rhizoma Polygoni Cuspidati 33g, Radix Rehmanniae 19g, Radix Sanguisorbae 41g, Herba Taraxaci 22g, Radix Arnebiae (Radix Lithospermi) 14g, Radix Angelicae Sinensis 26g.
This compound recipe artificial skin is the method for employing heat medicine-feeding, Chinese medicine is first heated to 260 DEG C and makes the rear use of medicine boiling, be then cooled to 70-80C °, then add medicine at wound to patient.Secondary not only can not be caused to scald, and can effectively promote wound surface quickly-healing, ooze out at preventing humor simultaneously, infection, relieve the pain, substitute skin grafting etc. in performance very outstanding.
Claims (9)
1. a compound recipe artificial skin, is characterized in that, comprises following raw material: Oleum sesami, Borneolum Syntheticum, Moschus, Stigma Croci, Sanguis Draxonis, catechu, Radix Et Rhizoma Rhei, the Radix Angelicae Dahuricae, Rhizoma Coptidis, Rhizoma Polygoni Cuspidati, the Radix Rehmanniae, Radix Sanguisorbae, Herba Taraxaci, Radix Arnebiae (Radix Lithospermi), Radix Angelicae Sinensis.
2. compound recipe artificial skin according to claim 1, it is characterized in that, comprise the raw material of following weight portion: Oleum sesami 12 ~ 19 parts, Borneolum Syntheticum 12 ~ 17 parts, 0.06 ~ 0.10 part, Moschus, Stigma Croci 15 ~ 23 parts, Sanguis Draxonis 45 ~ 55 parts, 65 ~ 75 parts, catechu, Radix Et Rhizoma Rhei 48 ~ 58 parts, the Radix Angelicae Dahuricae 29 ~ 37 parts, Rhizoma Coptidis 40 ~ 48 parts, Rhizoma Polygoni Cuspidati 28 ~ 34 parts, 14 ~ 21 parts, the Radix Rehmanniae, Radix Sanguisorbae 37 ~ 43 parts, Herba Taraxaci 18 ~ 23 parts, Radix Arnebiae (Radix Lithospermi) 10 ~ 15 parts, Radix Angelicae Sinensis 21 ~ 27 parts.
3. compound recipe artificial skin according to claim 2, it is characterized in that, comprise the raw material of following weight portion: Oleum sesami 14 ~ 18 parts, Borneolum Syntheticum 13 ~ 16 parts, 0.07 ~ 0.09 part, Moschus, Stigma Croci 18 ~ 21 parts, Sanguis Draxonis 48 ~ 53 parts, 68 ~ 73 parts, catechu, Radix Et Rhizoma Rhei 52 ~ 56 parts, the Radix Angelicae Dahuricae 31 ~ 35 parts, Rhizoma Coptidis 42 ~ 46 parts, Rhizoma Polygoni Cuspidati 30 ~ 33 parts, 17 ~ 19 parts, the Radix Rehmanniae, Radix Sanguisorbae 39 ~ 41 parts, Herba Taraxaci 20 ~ 22 parts, Radix Arnebiae (Radix Lithospermi) 12 ~ 14 parts, Radix Angelicae Sinensis 23 ~ 26 parts.
4. compound recipe artificial skin according to claim 3, it is characterized in that, comprise the raw material of following weight portion: Oleum sesami 16 parts, Borneolum Syntheticum 15 parts, 0.08 part, Moschus, Stigma Croci 19 parts, Sanguis Draxonis 51 parts, 71 parts, catechu, Radix Et Rhizoma Rhei 55 parts, the Radix Angelicae Dahuricae 33 parts, Rhizoma Coptidis 44 parts, Rhizoma Polygoni Cuspidati 32 parts, 18 parts, the Radix Rehmanniae, Radix Sanguisorbae 40 parts, Herba Taraxaci 21 parts, Radix Arnebiae (Radix Lithospermi) 13 parts, Radix Angelicae Sinensis 25 parts.
5. compound recipe artificial skin according to claim 2, it is characterized in that, comprise the raw material of following weight portion: Oleum sesami 12 parts, Borneolum Syntheticum 12 parts, 0.06 part, Moschus, Stigma Croci 15 parts, Sanguis Draxonis 45 parts, 65 parts, catechu, Radix Et Rhizoma Rhei 48 parts, the Radix Angelicae Dahuricae 29 parts, Rhizoma Coptidis 40 parts, Rhizoma Polygoni Cuspidati 28 parts, 14 parts, the Radix Rehmanniae, Radix Sanguisorbae 37 parts, Herba Taraxaci 18 parts, Radix Arnebiae (Radix Lithospermi) 10 parts, Radix Angelicae Sinensis 21 parts.
6. compound recipe artificial skin according to claim 2, it is characterized in that, comprise the raw material of following weight portion: Oleum sesami 19 parts, Borneolum Syntheticum 17 parts, 0.10 part, Moschus, Stigma Croci 23 parts, Sanguis Draxonis 55 parts, 75 parts, catechu, Radix Et Rhizoma Rhei 58 parts, the Radix Angelicae Dahuricae 37 parts, Rhizoma Coptidis 48 parts, Rhizoma Polygoni Cuspidati 34 parts, 21 parts, the Radix Rehmanniae, Radix Sanguisorbae 43 parts, Herba Taraxaci 23 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, Radix Angelicae Sinensis 27 parts.
7. compound recipe artificial skin according to claim 3, it is characterized in that, comprise the raw material of following weight portion: Oleum sesami 14 parts, Borneolum Syntheticum 13 parts, 0.07 part, Moschus, Stigma Croci 18 parts, Sanguis Draxonis 48 parts, 68 parts, catechu, Radix Et Rhizoma Rhei 52 parts, the Radix Angelicae Dahuricae 31 parts, Rhizoma Coptidis 42 parts, Rhizoma Polygoni Cuspidati 30 parts, 17 parts, the Radix Rehmanniae, Radix Sanguisorbae 39 parts, Herba Taraxaci 20 parts, Radix Arnebiae (Radix Lithospermi) 12 parts, Radix Angelicae Sinensis 23 parts.
8. compound recipe artificial skin according to claim 3, it is characterized in that, comprise the raw material of following weight portion: Oleum sesami 18 parts, Borneolum Syntheticum 16 parts, 0.09 part, Moschus, Stigma Croci 21 parts, Sanguis Draxonis 53 parts, 73 parts, catechu, Radix Et Rhizoma Rhei 56 parts, the Radix Angelicae Dahuricae 35 parts, Rhizoma Coptidis 46 parts, Rhizoma Polygoni Cuspidati 33 parts, 19 parts, the Radix Rehmanniae, Radix Sanguisorbae 41 parts, Herba Taraxaci 22 parts, Radix Arnebiae (Radix Lithospermi) 14 parts, Radix Angelicae Sinensis 26 parts.
9. a preparation method for compound recipe artificial skin described in claim 1, comprises pulverizing, soak extraction and preparation, it is characterized in that, soaks 6 months; Preparation adopts Cera Flava as excipient.
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Cited By (1)
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| CN113274456A (en) * | 2021-05-24 | 2021-08-20 | 平顶山宙斯生物科技有限公司 | Chinese medicinal ointment for treating burn, scald, chemical burn, and electric injury, and its preparation method |
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Application publication date: 20151216 |