CN105147817B - A kind of Chinese materia medica preparation and preparation method thereof for treating ecphyaditis - Google Patents

A kind of Chinese materia medica preparation and preparation method thereof for treating ecphyaditis Download PDF

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CN105147817B
CN105147817B CN201510629303.4A CN201510629303A CN105147817B CN 105147817 B CN105147817 B CN 105147817B CN 201510629303 A CN201510629303 A CN 201510629303A CN 105147817 B CN105147817 B CN 105147817B
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materia medica
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CN105147817A (en
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杜春响
杜俊俊
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Shanghai spring Pharmaceutical Technology Co., Ltd.
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Abstract

The invention discloses a kind of Chinese materia medica preparations for treating ecphyaditis, are made of the bulk pharmaceutical chemicals for including following parts by weight: 28-36 parts of honeysuckle, 12-20 parts of Fructus Forsythiae, 9-20 parts of green peel, 8-14 parts of Fructus Aurantii, 8-15 parts of olibanum;Bulk pharmaceutical chemicals are uniformly mixed according to the ratio, are changed to mild fire after boiling with high heat after the pure water of addition 5-7 times of weight of bulk pharmaceutical chemicals gross weight immediately, and mild fire keeps boiling to stop heating, the first time being obtained by filtration fried liquid after five minutes;Continue to add water repetition is above-mentioned to boil medicine process twice, collects obtained filtrate three times, be uniformly mixed and the Chinese materia medica preparation is made.Chinese materia medica preparation of the present invention has clearing heat and detoxicating, carbuncle that disappears dissipating bind, gas consumption product and blood circulation invigorating efficacies, and treatment acute and chronic appendicitis has unique curative effect;During the treatment of the Chinese materia medica preparation, without operation without intravenously administrable, short treating period, curative effect are fast, cure rate is high, can fully recover within 1-3 days, cure rate reaches 98%.

Description

A kind of Chinese materia medica preparation and preparation method thereof for treating ecphyaditis
Technical field
The present invention relates to a kind of Chinese materia medica preparations, and in particular to a kind of Chinese materia medica preparation and preparation method thereof for treating ecphyaditis, Belong to the field of Chinese medicines.
Background technique
Ecphyaditis is common one of surgical disease, is divided into acute appendicitis and chronic appendicitis.At present for acute door screen For the treatment of tail inflammation generally using operation resectional therapy, this brings very big inconvenience even pain to patient.Even chronic appendicitis, Doctor trained in Western medicine takes conservative therapy, and using intravenous drip antibiotic as main therapy;Since chronic appendicitis cannot be controlled effectively, It still need to finally perform the operation and carry out excision treatment.So far, yet there are no oral administration can treat on the Chinese medicine of acute and chronic appendicitis City.
Summary of the invention
The technical problem to be solved by the present invention is to be directed to the deficiencies in the prior art, and provide a kind of to treat appendix Scorching Chinese materia medica preparation, the Chinese materia medica preparation have effects that clearing heat and detoxicating, carbuncle that disappears dissipating bind, gas consumption product and activating microcirculation and removing stasis medicinal, take orally There is splendid curative effect to acute and chronic ecphyaditis afterwards.
A second object of the present invention is to provide a kind of preparation methods of above-mentioned Chinese materia medica preparation.
To achieve the goals above, the present invention adopts the following technical scheme:
A kind of Chinese materia medica preparation for treating ecphyaditis is made of the bulk pharmaceutical chemicals for including following parts by weight: 28-36 parts of honeysuckle, 12-20 parts of Fructus Forsythiae, 9-20 parts of green peel, 8-14 parts of Fructus Aurantii, 8-15 parts of olibanum.
In the preferred technical solution of the present invention, the bulk pharmaceutical chemicals are as follows: 34 parts of honeysuckle, 18 parts of Fructus Forsythiae, 18 parts of green peel, trifoliate orange 12 parts of shell, 12 parts of olibanum.
In the preferred technical solution of the present invention, the bulk pharmaceutical chemicals are as follows: 32 parts of honeysuckle, 17 parts of Fructus Forsythiae, 11 parts of green peel, trifoliate orange 11 parts of shell, 11 parts of olibanum.
In the preferred technical solution of the present invention, the bulk pharmaceutical chemicals are as follows: 30 parts of honeysuckle, 15 parts of Fructus Forsythiae, 10 parts of green peel, trifoliate orange 10 parts of shell, 10 parts of olibanum.
In the preferred technical solution of the present invention, the bulk pharmaceutical chemicals are as follows: 31 parts of honeysuckle, 16 parts of Fructus Forsythiae, 10 parts of green peel, trifoliate orange 10 parts of shell, 10 parts of olibanum.
The present invention also provides a kind of preparation methods of above-mentioned Chinese materia medica preparation, by above-mentioned each bulk pharmaceutical chemicals according to conventional treatment method Broken, various broken bulk pharmaceutical chemicals are uniformly mixed according to the ratio and are placed in container of decocting medicinal herbs, and add into container of decocting medicinal herbs It is boiled with high heat after entering the pure water of 5-7 times of weight of bulk pharmaceutical chemicals gross weight, is changed to mild fire after boiling immediately, mild fire keeps 5 points of boiling Stop heating after clock, obtains fried liquid for the first time with 150-300 mesh silk cover filtering;Continue that bulk pharmaceutical chemicals gross weight is added into container of decocting medicinal herbs The pure water of 5-7 times of weight, is changed to mild fire immediately after boiling by intense fire, mild fire keeps boiling to stop heating after five minutes, uses 150- 300 mesh silk cover filterings obtain second of fried liquid;Continue the pure water that 5-7 times of weight of bulk pharmaceutical chemicals gross weight is added into container of decocting medicinal herbs, Mild fire is changed to after boiling by intense fire immediately, mild fire keeps boiling to stop heating after five minutes, obtains third with 150-300 mesh silk cover filtering Secondary fried liquid;Merge fried liquid three times and is uniformly mixed the Chinese materia medica preparation that treatment ecphyaditis of the present invention is made.
The pure water refers to commercially available common pure water, and bottled or drummed pure water can be with.
The bulk pharmaceutical chemicals are broken according to conventional treatment method, refer to bulk pharmaceutical chemicals according to " Chinese Pharmacopoeia " (2010) reference book Necessary, the conventional treatment process and processing requirement recorded is handled and is crushed.
The instructions of taking of Chinese materia medica preparation of the present invention are as follows: suffer from the patient of acute appendicitis, every 2-3 hours takes drugs Once, 300ml is taken orally every time, until recovery from illness, reasonable computation time when taking drugs, is guaranteed as far as possible early, middle and late half small before meals When within respectively take drugs it is primary;Suffer from the patient of chronic appendicitis, respectively takes medicine within half an hour before meals early, middle and late daily Object is primary, once takes 300ml, until recovery from illness;Patient avoids cold and uncooked food maror during taking Chinese materia medica preparation of the invention.This The invention Chinese materia medica preparation, can decoct daily and take medical fluid;Decoction can also be obtained to medical fluid to refrigerate in -4 DEG C of environment, The medical fluid that can be taken in 6 months.
The advantages of technical solution of the present invention, is.
Chinese materia medica preparation compatibility of the present invention is reasonable, using honeysuckle, Fructus Forsythiae as monarch drug in a prescription, both medicines primarily serve it is clearing heat and detoxicating, The effect of carbuncle that disappears dissipating bind;Using green peel, Fructus Aurantii as ministerial drug, has effects that gas consumption product, olibanum activating microcirculation and removing stasis medicinal is adjutant in addition;It should Chinese materia medica preparation has clearing heat and detoxicating, carbuncle that disappears dissipating bind, gas consumption product and blood circulation invigorating efficacies, and treatment acute and chronic appendicitis has only Special curative effect;During the treatment for taking the Chinese materia medica preparation, without operation without intravenously administrable, short treating period, curative effect be fast, cure rate Height can fully recover for 1-3 days, and cure rate reaches 98% or more.
Specific embodiment
The specific embodiment of technical solution of the present invention is described in detail below, but the present invention is not limited in being described below Hold:
Embodiment 1:
A kind of Chinese materia medica preparation for treating ecphyaditis is made: honeysuckle 34g, Fructus Forsythiae of the bulk pharmaceutical chemicals for including following parts by weight 18g, green peel 18g, Fructus Aurantii 12g, olibanum 12g;
Above-mentioned Chinese materia medica preparation is prepared by following methods: above-mentioned each bulk pharmaceutical chemicals are broken according to conventional treatment method Broken, various broken bulk pharmaceutical chemicals are uniformly mixed according to the ratio and are placed in container of decocting medicinal herbs, and are added into container of decocting medicinal herbs It is boiled with high heat after 500ml drummed pure water, is changed to mild fire after boiling immediately, mild fire keeps boiling to stop heating after five minutes, uses 200 mesh silk cover filterings obtain fried liquid (300ml or so) for the first time;Continue after 500ml drummed pure water is added into container of decocting medicinal herbs It boils with high heat, is changed to mild fire after boiling by intense fire immediately, mild fire keeps boiling to stop heating after five minutes, with 200 mesh silk cover filterings Obtain second of fried liquid (300ml or so);Continue to boil with high heat after 500ml drummed pure water is added into container of decocting medicinal herbs, it is military Fire is changed to mild fire immediately after boiling, mild fire keeps boiling to stop heating after five minutes, and it is fried to obtain third time with 200 mesh silk cover filterings Liquid (300ml or so);Merge fried liquid three times and is uniformly mixed the Chinese materia medica preparation that treatment ecphyaditis of the present invention is made.
Embodiment 2:
A kind of Chinese materia medica preparation for treating ecphyaditis is made: honeysuckle 32g, Fructus Forsythiae of the bulk pharmaceutical chemicals for including following parts by weight 17g, green peel 11g, Fructus Aurantii 11g, olibanum 11g;
Above-mentioned Chinese materia medica preparation is prepared by following methods: above-mentioned each bulk pharmaceutical chemicals are broken according to conventional treatment method Broken, various broken bulk pharmaceutical chemicals are uniformly mixed according to the ratio and are placed in container of decocting medicinal herbs, and are added into container of decocting medicinal herbs It is boiled with high heat after 500ml drummed pure water, is changed to mild fire after boiling immediately, mild fire keeps boiling to stop heating after five minutes, uses 200 mesh silk cover filterings obtain fried liquid (300ml or so) for the first time;Continue after 500ml drummed pure water is added into container of decocting medicinal herbs It boils with high heat, is changed to mild fire after boiling by intense fire immediately, mild fire keeps boiling to stop heating after five minutes, with 200 mesh silk cover filterings Obtain second of fried liquid (300ml or so);Continue to boil with high heat after 500ml drummed pure water is added into container of decocting medicinal herbs, it is military Fire is changed to mild fire immediately after boiling, mild fire keeps boiling to stop heating after five minutes, and it is fried to obtain third time with 200 mesh silk cover filterings Liquid (300ml or so);Merge fried liquid three times and is uniformly mixed the Chinese materia medica preparation that treatment ecphyaditis of the present invention is made.
Embodiment 3:
A kind of Chinese materia medica preparation for treating ecphyaditis is made: honeysuckle 30g, Fructus Forsythiae of the bulk pharmaceutical chemicals for including following parts by weight 15g, green peel 10g, Fructus Aurantii 10g, olibanum 10g;
Above-mentioned Chinese materia medica preparation is prepared by following methods: above-mentioned each bulk pharmaceutical chemicals are broken according to conventional treatment method Broken, various broken bulk pharmaceutical chemicals are uniformly mixed according to the ratio and are placed in container of decocting medicinal herbs, and are added into container of decocting medicinal herbs It is boiled with high heat after 500ml drummed pure water, is changed to mild fire after boiling immediately, mild fire keeps boiling to stop heating after five minutes, uses 200 mesh silk cover filterings obtain fried liquid (300ml or so) for the first time;Continue after 500ml drummed pure water is added into container of decocting medicinal herbs It boils with high heat, is changed to mild fire after boiling by intense fire immediately, mild fire keeps boiling to stop heating after five minutes, with 200 mesh silk cover filterings Obtain second of fried liquid (300ml or so);Continue to boil with high heat after 500ml drummed pure water is added into container of decocting medicinal herbs, it is military Fire is changed to mild fire immediately after boiling, mild fire keeps boiling to stop heating after five minutes, and it is fried to obtain third time with 200 mesh silk cover filterings Liquid (300ml or so);Merge fried liquid three times and is uniformly mixed the Chinese materia medica preparation that treatment ecphyaditis of the present invention is made.
Embodiment 4:
A kind of Chinese materia medica preparation for treating ecphyaditis is made: 31 parts of honeysuckle, Fructus Forsythiae of the bulk pharmaceutical chemicals for including following parts by weight 16 parts, 10 parts of green peel, 10 parts of Fructus Aurantii, 10 parts of olibanum;
Above-mentioned Chinese materia medica preparation is prepared by following methods: above-mentioned each bulk pharmaceutical chemicals are broken according to conventional treatment method Broken, various broken bulk pharmaceutical chemicals are uniformly mixed according to the ratio and are placed in container of decocting medicinal herbs, and are added into container of decocting medicinal herbs It is boiled with high heat after 500ml drummed pure water, is changed to mild fire after boiling immediately, mild fire keeps boiling to stop heating after five minutes, uses 200 mesh silk cover filterings obtain fried liquid (300ml or so) for the first time;Continue after 500ml drummed pure water is added into container of decocting medicinal herbs It boils with high heat, is changed to mild fire after boiling by intense fire immediately, mild fire keeps boiling to stop heating after five minutes, with 200 mesh silk cover filterings Obtain second of fried liquid (300ml or so);Continue to boil with high heat after 500ml drummed pure water is added into container of decocting medicinal herbs, it is military Fire is changed to mild fire immediately after boiling, mild fire keeps boiling to stop heating after five minutes, and it is fried to obtain third time with 200 mesh silk cover filterings Liquid (300ml or so);Merge fried liquid three times and is uniformly mixed the Chinese materia medica preparation that treatment ecphyaditis of the present invention is made.
The clinical efficacy of the resulting oral traditional Chinese medicine composition of the embodiment of the present invention 3:
1, treatment method:
1.1, patient grouping
All patients pass through both from hospital outpatient or inpatient (accepting 500 between 2000-2015 August for medical treatment altogether) Laboratory leukocyte value increases with ultrasound diagnosis appendix congestion and edema as a result, 500 patients are divided into acute appendicitis and chronic appendix It is two groups scorching: the patient 318 (male 219, female 99, average age 37 years old) for suffering from acute appendicitis, wherein simple appendicitis 98, celluar tissue inflammatory ecphyaditis 220;Suffer from chronic appendicitis patient 182 (male 76, female 106, average age 28 years old), the chronic appendicitis is gangrenous appendicitis.
According to Chinese medical discrimination method, above-mentioned acute appendicitis and chronic appendicitis be properly termed as again heat-toxin type ecphyaditis and Qi stagnation and blood stasis type ecphyaditis.
1.2 treatment method
Suffer from the patient of acute appendicitis, every 2-3 hours to take Chinese materia medica preparation prepared with embodiment 3 primary, oral every time 300ml guarantees respectively to take drugs within early, middle and late half an hour before meals primary;Suffer from the patient of chronic appendicitis, early daily, In, within half an hour before meals in evening respectively to take Chinese materia medica preparation prepared with embodiment 3 primary, once take 300ml;Avoid during treatment Raw and cold maror.
1.3, curative effect determinate standard:
Invalid: to the patient seriously vomitted, what cannot be taken medicine is then invalid.
Effective: body temperature is down to normal (37 DEG C or less), and wbc value is down to normal (4000-1000/mm3), ultrasound diagnosis door screen The visible expansion pipe echo of tail, proximal end caecum thickening disappear, and symptom (the pain performance that patient states Xiang doctor) is eliminated.
Recovery from illness: body temperature is down to normally, the sings and symptoms (disease with diagnostic significance that doctor has found when checking to patient Wait, such as Right Lower Abdomen mcBurney point rebound tenderness etc.) all disappear, wbc value is down to normal (4000-1000/mm3), ultrasound diagnosis The visible expansion pipe echo of appendix, proximal end caecum thickening disappear.
2, result:
Table 1: clinic medication observation of curative effect list
As shown in Table 1, Chinese materia medica preparation of the present invention 2-3 days can after the patient with acute appendicitis takes Recovery from illness, cure rate reach 100%;After patient with chronic appendicitis takes, it can fully recover within 3 days, cure rate reaches 100%.Chinese materia medica preparation of the invention, short treating period, cure rate are high, are not necessarily to operative treatment, are administered without intravenous injection, therefore, During treatment, any adverse effect not will cause to the body of patient, the inconvenience and discomfort of patient will not be caused.Also, After taking Chinese medicine preparation treatment ecphyaditis of the present invention, the hepatic and renal function pretherapy and post-treatment to patient checks that inspection result shows Hepatic and renal function is normal before and after treatment, shows that Chinese materia medica preparation of the invention is harmless to internal organs such as liver kidneys.
Examples detailed above is technical conception and technical characteristics to illustrate the invention, can not be limited with this of the invention Protection scope.The equivalent transformation or modification that all essence according to the present invention is done, should all cover in protection scope of the present invention Within.

Claims (6)

1. a kind of Chinese materia medica preparation for treating ecphyaditis, which is characterized in that be prepared from the following raw materials in parts by weight: honeysuckle 28- 36 parts, 12-20 parts of Fructus Forsythiae, 9-20 parts of green peel, 8-14 parts of Fructus Aurantii, 8-15 parts of olibanum.
2. oral traditional Chinese medicine composition according to claim 1, which is characterized in that the bulk pharmaceutical chemicals are as follows: 34 parts of honeysuckle, 18 parts of Fructus Forsythiae, 18 parts of green peel, 12 parts of Fructus Aurantii, 12 parts of olibanum.
3. oral traditional Chinese medicine composition according to claim 1, which is characterized in that the bulk pharmaceutical chemicals are as follows: 32 parts of honeysuckle, 17 parts of Fructus Forsythiae, 11 parts of green peel, 11 parts of Fructus Aurantii, 11 parts of olibanum.
4. oral traditional Chinese medicine composition according to claim 1, which is characterized in that the bulk pharmaceutical chemicals are as follows: 30 parts of honeysuckle, 15 parts of Fructus Forsythiae, 10 parts of green peel, 10 parts of Fructus Aurantii, 10 parts of olibanum.
5. oral traditional Chinese medicine composition according to claim 1, which is characterized in that the bulk pharmaceutical chemicals are as follows: 31 parts of honeysuckle, 16 parts of Fructus Forsythiae, 10 parts of green peel, 10 parts of Fructus Aurantii, 10 parts of olibanum.
6. the preparation method of the described in any item Chinese materia medica preparations of claim 1-5, which comprises the following steps: will be upper It is broken according to conventional treatment method to state each bulk pharmaceutical chemicals, various broken bulk pharmaceutical chemicals are uniformly mixed according to the ratio and are placed on It decocts medicinal herbs in container, is boiled with high heat after the pure water of 5-7 times of weight of bulk pharmaceutical chemicals gross weight is added into container of decocting medicinal herbs, after boiling immediately It is changed to mild fire, mild fire keeps boiling to stop heating after five minutes, obtains fried liquid for the first time with 150-300 mesh silk cover filtering;Continue to It decocts medicinal herbs and the pure water of 5-7 times of weight of bulk pharmaceutical chemicals gross weight is added in container, be changed to mild fire after boiling by intense fire immediately, mild fire keeps boiling Stop heating after five minutes, obtains second of fried liquid with 150-300 mesh silk cover filtering;Continue that bulk pharmaceutical chemicals are added into container of decocting medicinal herbs The pure water of 5-7 times of weight of gross weight is changed to mild fire immediately after boiling by intense fire, mild fire keeps boiling to stop heating after five minutes, uses 150-300 mesh silk cover filtering obtains the fried liquid of third time;Merge fried liquid three times and is uniformly mixed the Chinese medicine system that treatment ecphyaditis is made Agent.
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1245700A (en) * 1998-08-24 2000-03-01 杜春响 Chinese medicine for curing appendicitis
CN102552572A (en) * 2012-03-28 2012-07-11 尹尧光 Chinese medicine for treating appendicitis
CN102743510A (en) * 2012-07-08 2012-10-24 杨国华 Chinese medicine preparation for treating acute appendicitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1245700A (en) * 1998-08-24 2000-03-01 杜春响 Chinese medicine for curing appendicitis
CN102552572A (en) * 2012-03-28 2012-07-11 尹尧光 Chinese medicine for treating appendicitis
CN102743510A (en) * 2012-07-08 2012-10-24 杨国华 Chinese medicine preparation for treating acute appendicitis

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