CN105147805A

CN105147805A - Compound toona ciliata domiphen bromide agentia for external use

Info

Publication number: CN105147805A
Application number: CN201510697803.1A
Authority: CN
Inventors: 吕文今
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-10-23
Filing date: 2015-10-23
Publication date: 2015-12-16

Abstract

The invention discloses a compound toona ciliata domiphen bromide agentia for external use. The compound toona ciliata domiphen bromide agentia is mainly used for treating leukoplakia of vagina and has a remarkable treatment effect. The compound toona ciliata domiphen bromide agentia is prepared from toona ciliata, euscaphis japonica leaves, dendrolobium triangulare, pendulous euonymus barks or roots, denseleaf crazyweed herb, tall monkshood roots, dyetree, wild flax, schizomussaenda dehiscens, punctate ardisia herb, Chinese umbrellaleaf rhizome, quassia roots, weak equisetum, lignum rhamnellae, pogostemon auricularius, white quartz, cavalerie mosla, leontopodium leontopodioides, argyreia obtusifolia lour., polygonum lapathifolium L, sassafras tzumu, Indian melothria roots, zelkova schneideriana leaves, longleaf bastardtoadflax herb, domiphen bromide, oxytetracycline, bacitracin, dimethylacetamide, antioxidant, preservative, antisensitive agent and dispersing agent. Through reasonable compatibility of the ingredients, the functions of clearing heat and drying dampness, warming channel for arresting bleeding, eliminating cold to stop pain, dispelling wind and arresting itching and replenishing the vital essence and the blood are realized, and inflammation diminishing, bacterium resistance and allergy resistance are achieved. By the combination of Chinese medicine and western medicine, a good synergistic effect is realized. The agentia is for external use, and leukoplakia of female vagina can be effectively treated based on clinical verifications; furthermore, using is convenient, and treatment effect is remarkable.

Description

A kind of compound recipe toon domiphen bromide topical agent

Technical field

The present invention relates to medical art, specifically relate to a kind of compound recipe toon domiphen bromide topical agent.

Background technology

Vagina white macula (leukoplakiaofvagina) is more common in climacteric women, and current etiology unknown may be relevant with endocrine, and viral infection may be one of reason, and in addition, leucorrhea is many, does not notice that the chronic stimulations such as topical health can be predisposing factors.Leukoplakia vulvae can show as lichen sample syndrome.Leukoplakia vulvae often with pruritus, even serious pruritus, this normally lichen sclerosis in progressive mark.Pain also can occur, particularly when there is breach.Crack and ulcer are the marks of prognosis mala.Disease damage district expands, and vaginal orifice can be caused narrow, but nympha not atrophy.Except vestibule and urethral orifice, all can fall ill in other positions of cysthus, is many with clitoris, nympha and labium majus inner face.Early stage is not shaping white patch, and elasticity and gloss disappear, and can expand mutual fusion.Due to vaginal secretions dipping, often can thicken.Also have and only feel pruritus in early days, the person that later becomes into white macula.Late period skin lesion expand hardening, surperficial keratinization, coarse, hardening, in pearl white, nipple sample propagation or atrophy.Conscious acute pruritus, Chang Yin scratch secondary redness, chap, ulcer.There is secondary canceration possibility.

And current also more not effective medicine, therefore, inventor, according to clinical experience for many years, have developed a kind of quick-acting medicine for the treatment of this disease.

Summary of the invention

The technical problem that the present invention solves is to provide a kind of compound recipe toon domiphen bromide topical agent, is mainly used in treatment vagina white macula, evident in efficacy.

Technical scheme of the present invention is: a kind of compound recipe toon domiphen bromide topical agent, and component meter by weight, comprises following composition: toon 150 ~ 300 parts, wild crow Folium toonae sinensis 100 ~ 200 parts, Radix dendrolobii triangularis 120 ~ 200 parts, 80 ~ 150 parts, Pericarpium Citri Reticulatae Viride tree, Herba Oxytropis Myriophyllae 90 ~ 150 parts, Radix aconiti sinomontani 30 ~ 60 parts, 20 ~ 50 portions of Platycarya strobilacea, wild flax 60 ~ 100 parts, tree 50 ~ 100 parts, Radix Glycyrrhizae, Radix Ardisiae punctatae 40 ~ 80 parts, Rhizoma et Radix Diphylleiae 40 ~ 100 parts, Ramulus Et Folium Picrasmae root 30 ~ 60 parts, Herba Eguiseti Debilis 60 ~ 120 parts, Rhamnella gilgitica Mansf. Melch. 50 ~ 90 parts, water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 150 ~ 250 parts, Quartz Album 60 ~ 90 parts, spire Herba Moslae Cavaleriei 80 ~ 150 parts, Herba Leontopodii Leontopodioidis 70 ~ 150 parts, the silver back of the body 40 ~ 100 parts, rattan, Herb polygoni Lapathifolii 100 ~ 200 parts, Radix sassafratis 50 ~ 150 parts, Radix Melothriae Heterophyllae 50 ~ 100 parts, Folium zelkovae schneiderianae 90 ~ 150 parts, Herba Thesii Longifolii 60 ~ 120 parts, domiphen bromide 1.2 ~ 2.5 parts, oxytetracycline 2.0 ~ 2.5 parts, bacitracin 1.8 ~ 2.4 parts, dimethyl acetylamide 2.0 ~ 4.0 parts, antioxidant 1.0 ~ 3.4 parts, antiseptic 0.5 ~ 2.5 part, anti-allergic agent 0.3 ~ 1.0 part, dispersant 2.0 ~ 5.5 parts.

Wherein, toon: [nature and flavor] are bitter; Puckery; Be slightly cold.[function cures mainly] heat clearing and damp drying; Astringent therapy; Parasite killing.Main chronic diarrhea; Chronic dysentery; Discharging fresh blood stool; Metrorrhagia; Leukorrhagia; Seminal emission; Nebulousurine; Infantile malnutrition; Ascarid; Skin ulcer tinea.Wild crow Folium toonae sinensis: [nature and flavor] are micro-pungent; Bitter; Tepor.[function cures mainly] dispelling wind for relieving itching.Housewife's cysthus is itched.Radix dendrolobii triangularis: [nature and flavor] are pungent, sweet, cold.[function cures mainly] heat clearing away, removing heat from blood, strong muscle, bone strengthening, invigorating spleen to remove dampness.Cure mainly laryngalgia, diarrhoea, traumatic injury, fracture, hematmesis due to visceral injury.Pericarpium Citri Reticulatae Viride set: [function cures mainly] dysentery from the beginning of, fracture and injury, eczema scrotum, joint aches.Herba Oxytropis Myriophyllae: [nature and flavor] are sweet, cold.[return through] lung; Liver; Spleen channel.[function cures mainly] heat-clearing and toxic substances removing, detumescence, wind-damp dispelling, hemostasis, controls influenza, laryngopharynx swelling and pain, carbuncle pyogenic infections from tumour or sore, wound, blood stasis swelling, various hemorrhage.Radix aconiti sinomontani: [nature and flavor] toil, temperature, poisonous.[function cures mainly] expelling wind and removing dampness, regulating QI to relieve pain, promoting blood circulation to remove blood stasis.Dispelling the wind and dampness pathogens lumbago and skelalgia, eruptive disease is suffered from abdominal pain, stomachache, cardiopalmus, traumatic injury impairment caused by overstrain, scrofula, furuncle.Platycarya strobilacea: [nature and flavor] are bitter, cold.Poisonous.[function cures mainly] detoxifies, antipruritic, parasite killing.For furuncle toxic swelling, eczema scrotum, stubborn dermatitis [usage and dosage] can not be taken orally, suitable amount used externally, decoct washing or tender leaf put affected part on the skin.Wild flax: [nature and flavor] are sweet, flat.[function cures mainly] blood enriching and dryness moistening, removing toxic substances of dispeling the wind.For blood deficiency and constipation, skin pruritus, urticaria, sore swollen toxin.Tree Radix Glycyrrhizae: [nature and flavor] are sweet, flat.[function cures mainly] heat-clearing and toxic substances removing, antiinflammatory diuresis.Cure mainly tracheitis, bronchitis, cough due to lung-heat, pharyngolaryngitis, tonsillitis, oedema due to nephritis, urinary tract infection.Radix Ardisiae punctatae: [nature and flavor] bitter sweet, acrid, warm.[function cures mainly] promoting blood flow to regulate menstruation, timid wind dehumidifying.Control amenorrhea, dysmenorrhea, rheumatic arthralgia, traumatic injury.Rhizoma et Radix Diphylleiae: [nature and flavor] are bitter; Pungent; Property is put down.[return through] liver; Kidney channel.[function cures mainly] be " Shaanxi Chinese herbal medicine " 1.: " wind-damp dispelling, clearing away heat and cooling blood, promoting blood circulation and stopping pain, and have discharge function.Treating rheumatic arthritis, lumbago and skelalgia, hectic fever due to YIN-deficiency consumptive fever, traumatic injury, menoxenia, few fu jie pain, carbuncle." 2. " the sweet peaceful blue or green Chinese herbal medicine choosing in Shan ": " expelling wind and removing dampness, drastically removing blood stasis and resolving static blood, pain relieving, removing toxic substances." Ramulus Et Folium Picrasmae root: [nature and flavor] bitter in the mouth; Cold in nature; Mild toxicity.[function cures mainly] heat-clearing and toxic substances removing; Removing dampness and killing parasites.Main cold, fever; Acute gastroenteritis; Dysentery; Biliary tract infection; Ascariasis; Furuncle; Scabies; Eczema; Scald; Venom.Herba Eguiseti Debilis: [nature and flavor] sweet micro-hardship is cool.[function cures mainly] " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " loose liver man pent-up.(controlling order) is sudden and violent also, distending pain, and nebula removing film, disappear pterygium.Doublely control five types of stranguria, beautiful stem pain, also white turbid urine.(radical cure) married woman leucorrhea with red and white discharge, removing blood stasis amasss, logical menstruation.Only large intestine hematochezia." Rhamnella gilgitica Mansf. Melch.: [nature and flavor] mildly bitter flavor; [function cures mainly] cool in nature dispeiling pathogenic wind and removing dampness; Detumescence sore.Main is inkstone wet arthritis; Grasserie; Leprosy; Monge disease.Water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis): [nature and flavor] pungent, micro-hardship is flat.[function cures mainly] clearing away heat and eliminating dampness, reducing swelling and alleviating pain.Cure mainly cold, fever.Eczema is controlled in external.Quartz Album: [nature and flavor] are sweet, tepor.[function cures mainly] tranquillizing and allaying excitement, cough-relieving, sending down the abnormal ascending QI.For uneasiness of palpitating with fear, cough with dyspnea.Warming the lung kidney, tranquilizing mind, diuresis.Control lung cold cough with asthma, sexual impotence, quench one's thirst, irritability, palpitate with fear forgetful, dysuria, jaundice, stony edema, anemofrigid-damp arthralgia.Spire Herba Moslae Cavaleriei: [nature and flavor] are pungent, tepor.[function cures mainly] diaphoresis expelling summer-heat, invigorating spleen to remove dampness, antipruritic, antidote against snake bite.For flu, heatstroke, acute gastroenteritis, dyspepsia, edema; Eczema is controlled in external, furuncle toxic swelling, treating swelling and pain by traumatic injury, venom.Herba Leontopodii Leontopodioidis: nature and flavor] bitter in the mouth; Cold in nature.[function cures mainly] clearing away heat and cooling blood, antiinflammatory diuresis, kidney tonifying diuretic.Main cold, fever; Pharyngolaryngitis; Nephritis.Silver back of the body rattan: [nature and flavor] are bitter; Pungent; Cool.[function cures mainly] dissipating blood stasis stops blooding.Main hematmesis due to visceral injury; Metrorrhagia; Leucorrhea with red and white discharge; Treating swelling and pain by traumatic injury.Herb polygoni Lapathifolii: [nature and flavor] are pungent, bitter, cool.[function cures mainly] heat-clearing and toxic substances removing, dampness removing is antipruritic.For enteritis, dysentery; Eczema is controlled in external, lymphoid tuberculosis.Radix sassafratis: [nature and flavor] are sweet, light, temperature.[function cures mainly] dispels the wind by wet, promoting blood circulation to remove blood stasis.For rheumatic arthritis, rheumatoid arthritis, lumbar muscle strain, chronic lambago and skelalgia, hemiplegia, traumatic injury, bruise; External is controlled on cutter hemorrhage.Radix Melothriae Heterophyllae: [nature and flavor] sweetness and bitterness, cold.[function cures mainly] replenishing YIN and blood, removing heat-phlegm, dampness removing, mass dissipating and swelling eliminating.Control heat syndrome cough, dysentery, gonorrhea, urinary tract infection, alcoholic jaundice, rheumatic arthralgia, laryngalgia, conjunctival congestion, eczema, carbuncle.Folium zelkovae schneiderianae: [nature and flavor] are bitter; Cold in nature.[function cures mainly] removing heat from blood, removing toxic substances.Main skin infection swells and ache; Metrorrhagia leukorrhagia.Herba Thesii Longifolii: [nature and flavor] work hard, cool.[function cures mainly] induces sweat, heat clearing away, and antiinflammatory parasite killing, dispels the wind, spasmolytic.Cure cold, heatstroke, infantile pneumonia, cough, infantile convulsion.

Further, described a kind of compound recipe toon domiphen bromide topical agent, component meter by weight, also comprises following composition: turn celery 100 ~ 200 parts, 150 ~ 250 parts, birch peach tree, turns celery acrid in the mouth, warm in nature, delivers and dispel the wind, warming spleen and stomach for dispelling cold, regulating QI to relieve pain; Birch peach tree sweet in the mouth, pungent, warm in nature, warming spleen and stomach for dispelling cold, expelling wind and removing dampness.

Further, described a kind of compound recipe toon domiphen bromide topical agent, component meter by weight, also comprises following composition: Lindernia ruellioides (Colsm.) Pennell 30 ~ 60 parts, purple stem rib celery 90 ~ 150 parts, Lindernia ruellioides (Colsm.) Pennell sweet in the mouth, light, and property is put down, vital energy regualting and blood circulation-promoting, removing toxic substances and promoting subsidence of swelling; Purple stem rib celery acrid in the mouth, warm in nature, vital energy regualting and blood circulation-promoting, pain relieving, cures mainly menoxenia, the stagnant stomachache of the stasis of blood.

Further, described a kind of compound recipe toon domiphen bromide topical agent, component meter by weight, also comprises following composition: Cor Gigeriae Galli 7 60 ~ 100 parts, Herba Violae arcuatae 60 ~ 90 parts, and Cor Gigeriae Galli seven taste is micro-sweet, cool in nature, heat-clearing and toxic substances removing, promoting the flow of QI in the collateral by warming the meridian, promoting blood circulation and hemostasis, synthetism; Herba Violae arcuatae acrid in the mouth fiber crops, warm in nature, promoting the flow of QI in the collateral by warming the meridian, stopping bleeding and knitting the fractured bone.

Further, described antioxidant is nimbecetin, and nimbecetin also has effect of antiinflammatory, antiulcer, function of gallbladder promoting diuresis.

Further, described antiseptic is potassium sorbate, and Chinese herbal medicine extract is easily corrupt, and adding a certain amount of antiseptic can extend its storage life greatly, ensures drug effect.

Further, described anti-allergic agent is that monarch of benzene, has good protective effect for easily irritated sensitive skin, expands medicinal application scope.

Further, described dispersant is Macrogol 200 or PEG400, all the components in medicine can be made dispersed, form homogeneous liquid.

The preparation method of this compound recipe toon domiphen bromide topical agent is as follows:

(1) toon is taken by proportioning, wild crow Folium toonae sinensis, Radix dendrolobii triangularis, Pericarpium Citri Reticulatae Viride is set, Herba Oxytropis Myriophyllae, Radix aconiti sinomontani, Platycarya strobilacea, wild flax, tree Radix Glycyrrhizae, Radix Ardisiae punctatae, Rhizoma et Radix Diphylleiae, Ramulus Et Folium Picrasmae root, Herba Eguiseti Debilis, Rhamnella gilgitica Mansf. Melch., water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Quartz Album, spire Herba Moslae Cavaleriei, Herba Leontopodii Leontopodioidis, silver back of the body rattan, Herb polygoni Lapathifolii, Radix sassafratis, Radix Melothriae Heterophyllae, Folium zelkovae schneiderianae, Herba Thesii Longifolii, turn celery, birch peach tree, Lindernia ruellioides (Colsm.) Pennell, purple stem rib celery, Cor Gigeriae Galli seven, Herba Violae arcuatae, clean, dry, be ground into 40 ~ 60 order coarse powder, be placed in extraction pot, add the water of 8 ~ 10 times amount, 98 ~ 99 DEG C of micro-reflux, extract, 40 ~ 50min that boil, by extracting solution 150 ~ 200 order filter-cloth filterings, adopting thin film evaporation concentrator filtrate to be concentrated into effective ingredient content is 10 ~ 15%, obtain Chinese herbal medicine extract, stand-by,

(2) domiphen bromide is taken by proportioning, oxytetracycline, bacitracin, dimethyl acetylamide, anti-allergic agent, dispersant, the Chinese herbal medicine extract obtained in step (1) is added in dispensing canister, and carry out hyperthermic treatment according to 0.2 ~ 0.5 DEG C/min, being adjusted to temperature is that 44 ~ 48 DEG C of constant temperature leave standstill process 10 ~ 15min, add dimethyl acetylamide and dispersant, mixing speed is adopted to be 65 ~ 75r/min stir process, to be mixed complete after, continue again to carry out hyperthermic treatment according to 0.2 ~ 0.5 DEG C/min, being adjusted to temperature is 52 ~ 54 DEG C, by domiphen bromide, oxytetracycline, bacitracin, anti-allergic agent adds in dispensing canister, mixing speed is adopted to be 65 ~ 75r/min stir process, 10 ~ 15min, after mixing, stand-by,

(3) take antioxidant, antiseptic by proportioning, join in the medicinal liquid after the final mixing of step (2), utilize instant sterilizer sterilizing, then subpackage.

Operation instruction:

Using method: get medicament of the present invention spraying 3 ~ 5ml/ time after pudendum cleaning, once a day, 7 days be a course for the treatment of, general 2 ~ 4 courses for the treatment of can heal entirely.

Points for attention: avoid edible pungent stimulation food, diet should be light, notes keeping pudendum cleaning health.

Taboo: gestation and nursing women's forbidding.

The invention has the beneficial effects as follows, reasonable compatibility uses multiple Chinese herbal medicine, plays the effect of heat clearing and damp drying, warming the meridian for stopping bleeding, dispersing cold for relieving pain, dispelling wind for relieving itching, replenishing YIN and blood, the antiinflammatory of western medicine composition energy, antibacterial, antiallergic, selected Chinese medicine and western medicine composition share, and has good synergism.This medicament is medicine for external use, through clinical verification, can effectively treat vagina white macula, and easy to use, evident in efficacy.

Detailed description of the invention

Embodiment 1:

A kind of compound recipe toon domiphen bromide topical agent, component meter by weight, comprise following composition: toon 150 parts, wild crow Folium toonae sinensis 100 parts, Radix dendrolobii triangularis 120 parts, Pericarpium Citri Reticulatae Viride sets 80 parts, Herba Oxytropis Myriophyllae 90 parts, Radix aconiti sinomontani 30 parts, 20 portions of Platycarya strobilacea, wild flax 60 parts, tree 50 parts, Radix Glycyrrhizae, Radix Ardisiae punctatae 40 parts, Rhizoma et Radix Diphylleiae 40 parts, Ramulus Et Folium Picrasmae root 30 parts, Herba Eguiseti Debilis 60 parts, Rhamnella gilgitica Mansf. Melch. 50 parts, water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 150 parts, Quartz Album 60 parts, spire Herba Moslae Cavaleriei 80 parts, Herba Leontopodii Leontopodioidis 70 parts, the silver back of the body 40 parts, rattan, Herb polygoni Lapathifolii 100 parts, Radix sassafratis 50 parts, Radix Melothriae Heterophyllae 50 parts, Folium zelkovae schneiderianae 90 parts, Herba Thesii Longifolii 60 parts, domiphen bromide 1.2 parts, oxytetracycline 2.0 parts, bacitracin 1.8 parts, dimethyl acetylamide 2.0 parts, antioxidant 1.0 parts, antiseptic 0.5 part, anti-allergic agent 0.3 part, dispersant 2.0 parts.

Wherein, described antioxidant is nimbecetin, and nimbecetin also has effect of antiinflammatory, antiulcer, function of gallbladder promoting diuresis.Described antiseptic is potassium sorbate, and Chinese herbal medicine extract is easily corrupt, and adding a certain amount of antiseptic can extend its storage life greatly, ensures drug effect.Described anti-allergic agent is that monarch of benzene, has good protective effect for easily irritated sensitive skin, expands medicinal application scope.Described dispersant is Macrogol 200 or PEG400, all the components in medicine can be made dispersed, form homogeneous liquid.

(1) toon is taken by proportioning, wild crow Folium toonae sinensis, Radix dendrolobii triangularis, Pericarpium Citri Reticulatae Viride is set, Herba Oxytropis Myriophyllae, Radix aconiti sinomontani, Platycarya strobilacea, wild flax, tree Radix Glycyrrhizae, Radix Ardisiae punctatae, Rhizoma et Radix Diphylleiae, Ramulus Et Folium Picrasmae root, Herba Eguiseti Debilis, Rhamnella gilgitica Mansf. Melch., water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Quartz Album, spire Herba Moslae Cavaleriei, Herba Leontopodii Leontopodioidis, silver back of the body rattan, Herb polygoni Lapathifolii, Radix sassafratis, Radix Melothriae Heterophyllae, Folium zelkovae schneiderianae, Herba Thesii Longifolii, clean, dry, be ground into 40 order coarse powder, be placed in extraction pot, add the water of 8 times amount, 98 DEG C of micro-reflux, extract, 40min that boil, by extracting solution 150 order filter-cloth filterings, adopting thin film evaporation concentrator filtrate to be concentrated into effective ingredient content is 10%, obtain Chinese herbal medicine extract, stand-by,

(2) domiphen bromide is taken by proportioning, oxytetracycline, bacitracin, dimethyl acetylamide, anti-allergic agent, dispersant, the Chinese herbal medicine extract obtained in step (1) is added in dispensing canister, and carry out hyperthermic treatment according to 0.2 DEG C/min, being adjusted to temperature is that 44 DEG C of constant temperature leave standstill process 10min, add dimethyl acetylamide and dispersant, mixing speed is adopted to be 65r/min stir process, to be mixed complete after, continue again to carry out hyperthermic treatment according to 0.2 DEG C/min, being adjusted to temperature is 52 DEG C, by domiphen bromide, oxytetracycline, bacitracin, anti-allergic agent adds in dispensing canister, mixing speed is adopted to be 65r/min stir process, 10min, after mixing, stand-by,

Embodiment 2:

A kind of compound recipe toon domiphen bromide topical agent, component meter by weight, comprise following composition: toon 225 parts, wild crow Folium toonae sinensis 150 parts, Radix dendrolobii triangularis 160 parts, Pericarpium Citri Reticulatae Viride sets 115 parts, Herba Oxytropis Myriophyllae 120 parts, Radix aconiti sinomontani 45 parts, 35 portions of Platycarya strobilacea, wild flax 80 parts, tree 75 parts, Radix Glycyrrhizae, Radix Ardisiae punctatae 60 parts, Rhizoma et Radix Diphylleiae 70 parts, Ramulus Et Folium Picrasmae root 45 parts, Herba Eguiseti Debilis 90 parts, Rhamnella gilgitica Mansf. Melch. 70 parts, water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 200 parts, Quartz Album 75 parts, spire Herba Moslae Cavaleriei 115 parts, Herba Leontopodii Leontopodioidis 110 parts, the silver back of the body 70 parts, rattan, Herb polygoni Lapathifolii 150 parts, Radix sassafratis 100 parts, Radix Melothriae Heterophyllae 75 parts, Folium zelkovae schneiderianae 120 parts, Herba Thesii Longifolii 90 parts, domiphen bromide 1.85 parts, oxytetracycline 2.25 parts, bacitracin 2.1 parts, dimethyl acetylamide 3.0 parts, antioxidant 2.2 parts, antiseptic 1.5 parts, anti-allergic agent 0.65 part, dispersant 3.75 parts.

(1) toon is taken by proportioning, wild crow Folium toonae sinensis, Radix dendrolobii triangularis, Pericarpium Citri Reticulatae Viride is set, Herba Oxytropis Myriophyllae, Radix aconiti sinomontani, Platycarya strobilacea, wild flax, tree Radix Glycyrrhizae, Radix Ardisiae punctatae, Rhizoma et Radix Diphylleiae, Ramulus Et Folium Picrasmae root, Herba Eguiseti Debilis, Rhamnella gilgitica Mansf. Melch., water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Quartz Album, spire Herba Moslae Cavaleriei, Herba Leontopodii Leontopodioidis, silver back of the body rattan, Herb polygoni Lapathifolii, Radix sassafratis, Radix Melothriae Heterophyllae, Folium zelkovae schneiderianae, Herba Thesii Longifolii, clean, dry, be ground into 50 order coarse powder, be placed in extraction pot, add the water of 9 times amount, 98.5 DEG C of micro-reflux, extract, 45min that boil, by extracting solution 175 order filter-cloth filterings, adopting thin film evaporation concentrator filtrate to be concentrated into effective ingredient content is 12.5%, obtain Chinese herbal medicine extract, stand-by,

(2) domiphen bromide is taken by proportioning, oxytetracycline, bacitracin, dimethyl acetylamide, anti-allergic agent, dispersant, the Chinese herbal medicine extract obtained in step (1) is added in dispensing canister, and carry out hyperthermic treatment according to 0.35 DEG C/min, being adjusted to temperature is that 46 DEG C of constant temperature leave standstill process 12.5min, add dimethyl acetylamide and dispersant, mixing speed is adopted to be 70r/min stir process, to be mixed complete after, continue again to carry out hyperthermic treatment according to 0.35 DEG C/min, being adjusted to temperature is 53 DEG C, by domiphen bromide, oxytetracycline, bacitracin, anti-allergic agent adds in dispensing canister, mixing speed is adopted to be 70r/min stir process, 12.5min, after mixing, stand-by,

Embodiment 3:

A kind of compound recipe toon domiphen bromide topical agent, component meter by weight, comprise following composition: toon 300 parts, wild crow Folium toonae sinensis 200 parts, Radix dendrolobii triangularis 200 parts, Pericarpium Citri Reticulatae Viride sets 150 parts, Herba Oxytropis Myriophyllae 150 parts, Radix aconiti sinomontani 60 parts, 50 portions of Platycarya strobilacea, wild flax 100 parts, tree 100 parts, Radix Glycyrrhizae, Radix Ardisiae punctatae 80 parts, Rhizoma et Radix Diphylleiae 100 parts, Ramulus Et Folium Picrasmae root 60 parts, Herba Eguiseti Debilis 120 parts, Rhamnella gilgitica Mansf. Melch. 90 parts, water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 250 parts, Quartz Album 90 parts, spire Herba Moslae Cavaleriei 150 parts, Herba Leontopodii Leontopodioidis 150 parts, the silver back of the body 100 parts, rattan, Herb polygoni Lapathifolii 200 parts, Radix sassafratis 150 parts, Radix Melothriae Heterophyllae 100 parts, Folium zelkovae schneiderianae 150 parts, Herba Thesii Longifolii 120 parts, domiphen bromide 2.5 parts, oxytetracycline 2.5 parts, bacitracin 2.4 parts, dimethyl acetylamide 4.0 parts, antioxidant 3.4 parts, antiseptic 2.5 parts, anti-allergic agent 1.0 parts, dispersant 5.5 parts.

(1) toon is taken by proportioning, wild crow Folium toonae sinensis, Radix dendrolobii triangularis, Pericarpium Citri Reticulatae Viride is set, Herba Oxytropis Myriophyllae, Radix aconiti sinomontani, Platycarya strobilacea, wild flax, tree Radix Glycyrrhizae, Radix Ardisiae punctatae, Rhizoma et Radix Diphylleiae, Ramulus Et Folium Picrasmae root, Herba Eguiseti Debilis, Rhamnella gilgitica Mansf. Melch., water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Quartz Album, spire Herba Moslae Cavaleriei, Herba Leontopodii Leontopodioidis, silver back of the body rattan, Herb polygoni Lapathifolii, Radix sassafratis, Radix Melothriae Heterophyllae, Folium zelkovae schneiderianae, Herba Thesii Longifolii, clean, dry, be ground into 60 order coarse powder, be placed in extraction pot, add the water of 10 times amount, 99 DEG C of micro-reflux, extract, 50min that boil, by extracting solution 200 order filter-cloth filterings, adopting thin film evaporation concentrator filtrate to be concentrated into effective ingredient content is 15%, obtain Chinese herbal medicine extract, stand-by,

(2) domiphen bromide is taken by proportioning, oxytetracycline, bacitracin, dimethyl acetylamide, anti-allergic agent, dispersant, the Chinese herbal medicine extract obtained in step (1) is added in dispensing canister, and carry out hyperthermic treatment according to 0.5 DEG C/min, being adjusted to temperature is that 48 DEG C of constant temperature leave standstill process 15min, add dimethyl acetylamide and dispersant, mixing speed is adopted to be 75r/min stir process, to be mixed complete after, continue again to carry out hyperthermic treatment according to 0.5 DEG C/min, being adjusted to temperature is 54 DEG C, by domiphen bromide, oxytetracycline, bacitracin, anti-allergic agent adds in dispensing canister, mixing speed is adopted to be 75r/min stir process, 15min, after mixing, stand-by,

Embodiment 4:

A kind of compound recipe toon domiphen bromide topical agent, component meter by weight, comprise following composition: toon 150 parts, wild crow Folium toonae sinensis 100 parts, Radix dendrolobii triangularis 120 parts, Pericarpium Citri Reticulatae Viride sets 80 parts, Herba Oxytropis Myriophyllae 90 parts, Radix aconiti sinomontani 30 parts, 20 portions of Platycarya strobilacea, wild flax 60 parts, tree 50 parts, Radix Glycyrrhizae, Radix Ardisiae punctatae 40 parts, Rhizoma et Radix Diphylleiae 40 parts, Ramulus Et Folium Picrasmae root 30 parts, Herba Eguiseti Debilis 60 parts, Rhamnella gilgitica Mansf. Melch. 50 parts, water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 150 parts, Quartz Album 60 parts, spire Herba Moslae Cavaleriei 80 parts, Herba Leontopodii Leontopodioidis 70 parts, the silver back of the body 40 parts, rattan, Herb polygoni Lapathifolii 100 parts, Radix sassafratis 50 parts, Radix Melothriae Heterophyllae 50 parts, Folium zelkovae schneiderianae 90 parts, Herba Thesii Longifolii 60 parts, domiphen bromide 1.2 parts, oxytetracycline 2.0 parts, bacitracin 1.8 parts, dimethyl acetylamide 2.0 parts, antioxidant 1.0 parts, antiseptic 0.5 part, anti-allergic agent 0.3 part, dispersant 2.0 parts, turn celery 100 parts, 150 parts, birch peach tree.

(1) toon is taken by proportioning, wild crow Folium toonae sinensis, Radix dendrolobii triangularis, Pericarpium Citri Reticulatae Viride is set, Herba Oxytropis Myriophyllae, Radix aconiti sinomontani, Platycarya strobilacea, wild flax, tree Radix Glycyrrhizae, Radix Ardisiae punctatae, Rhizoma et Radix Diphylleiae, Ramulus Et Folium Picrasmae root, Herba Eguiseti Debilis, Rhamnella gilgitica Mansf. Melch., water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Quartz Album, spire Herba Moslae Cavaleriei, Herba Leontopodii Leontopodioidis, silver back of the body rattan, Herb polygoni Lapathifolii, Radix sassafratis, Radix Melothriae Heterophyllae, Folium zelkovae schneiderianae, Herba Thesii Longifolii, turn celery, birch peach tree, clean, dry, be ground into 40 order coarse powder, be placed in extraction pot, add the water of 8 times amount, 98 DEG C of micro-reflux, extract, 40min that boil, by extracting solution 150 order filter-cloth filterings, adopting thin film evaporation concentrator filtrate to be concentrated into effective ingredient content is 10%, obtain Chinese herbal medicine extract, stand-by,

Embodiment 5:

A kind of compound recipe toon domiphen bromide topical agent, component meter by weight, comprise following composition: toon 225 parts, wild crow Folium toonae sinensis 150 parts, Radix dendrolobii triangularis 160 parts, Pericarpium Citri Reticulatae Viride sets 115 parts, Herba Oxytropis Myriophyllae 120 parts, Radix aconiti sinomontani 45 parts, 35 portions of Platycarya strobilacea, wild flax 80 parts, tree 75 parts, Radix Glycyrrhizae, Radix Ardisiae punctatae 60 parts, Rhizoma et Radix Diphylleiae 70 parts, Ramulus Et Folium Picrasmae root 45 parts, Herba Eguiseti Debilis 90 parts, Rhamnella gilgitica Mansf. Melch. 70 parts, water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 200 parts, Quartz Album 75 parts, spire Herba Moslae Cavaleriei 115 parts, Herba Leontopodii Leontopodioidis 110 parts, the silver back of the body 70 parts, rattan, Herb polygoni Lapathifolii 150 parts, Radix sassafratis 100 parts, Radix Melothriae Heterophyllae 75 parts, Folium zelkovae schneiderianae 120 parts, Herba Thesii Longifolii 90 parts, domiphen bromide 1.85 parts, oxytetracycline 2.25 parts, bacitracin 2.1 parts, dimethyl acetylamide 3.0 parts, antioxidant 2.2 parts, antiseptic 1.5 parts, anti-allergic agent 0.65 part, dispersant 3.75 parts, turn celery 150 parts, 200 parts, birch peach tree.

(1) toon is taken by proportioning, wild crow Folium toonae sinensis, Radix dendrolobii triangularis, Pericarpium Citri Reticulatae Viride is set, Herba Oxytropis Myriophyllae, Radix aconiti sinomontani, Platycarya strobilacea, wild flax, tree Radix Glycyrrhizae, Radix Ardisiae punctatae, Rhizoma et Radix Diphylleiae, Ramulus Et Folium Picrasmae root, Herba Eguiseti Debilis, Rhamnella gilgitica Mansf. Melch., water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Quartz Album, spire Herba Moslae Cavaleriei, Herba Leontopodii Leontopodioidis, silver back of the body rattan, Herb polygoni Lapathifolii, Radix sassafratis, Radix Melothriae Heterophyllae, Folium zelkovae schneiderianae, Herba Thesii Longifolii, turn celery, birch peach tree, clean, dry, be ground into 50 order coarse powder, be placed in extraction pot, add the water of 9 times amount, 98.5 DEG C of micro-reflux, extract, 45min that boil, by extracting solution 175 order filter-cloth filterings, adopting thin film evaporation concentrator filtrate to be concentrated into effective ingredient content is 12.5%, obtain Chinese herbal medicine extract, stand-by,

Embodiment 6:

A kind of compound recipe toon domiphen bromide topical agent, component meter by weight, comprise following composition: toon 300 parts, wild crow Folium toonae sinensis 200 parts, Radix dendrolobii triangularis 200 parts, Pericarpium Citri Reticulatae Viride sets 150 parts, Herba Oxytropis Myriophyllae 150 parts, Radix aconiti sinomontani 60 parts, 50 portions of Platycarya strobilacea, wild flax 100 parts, tree 100 parts, Radix Glycyrrhizae, Radix Ardisiae punctatae 80 parts, Rhizoma et Radix Diphylleiae 100 parts, Ramulus Et Folium Picrasmae root 60 parts, Herba Eguiseti Debilis 120 parts, Rhamnella gilgitica Mansf. Melch. 90 parts, water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 250 parts, Quartz Album 90 parts, spire Herba Moslae Cavaleriei 150 parts, Herba Leontopodii Leontopodioidis 150 parts, the silver back of the body 100 parts, rattan, Herb polygoni Lapathifolii 200 parts, Radix sassafratis 150 parts, Radix Melothriae Heterophyllae 100 parts, Folium zelkovae schneiderianae 150 parts, Herba Thesii Longifolii 120 parts, domiphen bromide 2.5 parts, oxytetracycline 2.5 parts, bacitracin 2.4 parts, dimethyl acetylamide 4.0 parts, antioxidant 3.4 parts, antiseptic 2.5 parts, anti-allergic agent 1.0 parts, dispersant 5.5 parts, turn celery 200 parts, 250 parts, birch peach tree.

(1) toon is taken by proportioning, wild crow Folium toonae sinensis, Radix dendrolobii triangularis, Pericarpium Citri Reticulatae Viride is set, Herba Oxytropis Myriophyllae, Radix aconiti sinomontani, Platycarya strobilacea, wild flax, tree Radix Glycyrrhizae, Radix Ardisiae punctatae, Rhizoma et Radix Diphylleiae, Ramulus Et Folium Picrasmae root, Herba Eguiseti Debilis, Rhamnella gilgitica Mansf. Melch., water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Quartz Album, spire Herba Moslae Cavaleriei, Herba Leontopodii Leontopodioidis, silver back of the body rattan, Herb polygoni Lapathifolii, Radix sassafratis, Radix Melothriae Heterophyllae, Folium zelkovae schneiderianae, Herba Thesii Longifolii, turn celery, birch peach tree, clean, dry, be ground into 60 order coarse powder, be placed in extraction pot, add the water of 10 times amount, 99 DEG C of micro-reflux, extract, 50min that boil, by extracting solution 200 order filter-cloth filterings, adopting thin film evaporation concentrator filtrate to be concentrated into effective ingredient content is 15%, obtain Chinese herbal medicine extract, stand-by,

Embodiment 7:

A kind of compound recipe toon domiphen bromide topical agent, component meter by weight, comprise following composition: toon 150 parts, wild crow Folium toonae sinensis 100 parts, Radix dendrolobii triangularis 120 parts, Pericarpium Citri Reticulatae Viride sets 80 parts, Herba Oxytropis Myriophyllae 90 parts, Radix aconiti sinomontani 30 parts, 20 portions of Platycarya strobilacea, wild flax 60 parts, tree 50 parts, Radix Glycyrrhizae, Radix Ardisiae punctatae 40 parts, Rhizoma et Radix Diphylleiae 40 parts, Ramulus Et Folium Picrasmae root 30 parts, Herba Eguiseti Debilis 60 parts, Rhamnella gilgitica Mansf. Melch. 50 parts, water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 150 parts, Quartz Album 60 parts, spire Herba Moslae Cavaleriei 80 parts, Herba Leontopodii Leontopodioidis 70 parts, the silver back of the body 40 parts, rattan, Herb polygoni Lapathifolii 100 parts, Radix sassafratis 50 parts, Radix Melothriae Heterophyllae 50 parts, Folium zelkovae schneiderianae 90 parts, Herba Thesii Longifolii 60 parts, domiphen bromide 1.2 parts, oxytetracycline 2.0 parts, bacitracin 1.8 parts, dimethyl acetylamide 2.0 parts, antioxidant 1.0 parts, antiseptic 0.5 part, anti-allergic agent 0.3 part, dispersant 2.0 parts, turn celery 100 parts, 150 parts, birch peach tree, Lindernia ruellioides (Colsm.) Pennell 30 parts, purple stem rib celery 90 parts.

(1) toon is taken by proportioning, wild crow Folium toonae sinensis, Radix dendrolobii triangularis, Pericarpium Citri Reticulatae Viride is set, Herba Oxytropis Myriophyllae, Radix aconiti sinomontani, Platycarya strobilacea, wild flax, tree Radix Glycyrrhizae, Radix Ardisiae punctatae, Rhizoma et Radix Diphylleiae, Ramulus Et Folium Picrasmae root, Herba Eguiseti Debilis, Rhamnella gilgitica Mansf. Melch., water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Quartz Album, spire Herba Moslae Cavaleriei, Herba Leontopodii Leontopodioidis, silver back of the body rattan, Herb polygoni Lapathifolii, Radix sassafratis, Radix Melothriae Heterophyllae, Folium zelkovae schneiderianae, Herba Thesii Longifolii, turn celery, birch peach tree, Lindernia ruellioides (Colsm.) Pennell, purple stem rib celery, clean, dry, be ground into 40 order coarse powder, be placed in extraction pot, add the water of 8 times amount, 98 DEG C of micro-reflux, extract, 40min that boil, by extracting solution 150 order filter-cloth filterings, adopting thin film evaporation concentrator filtrate to be concentrated into effective ingredient content is 10%, obtain Chinese herbal medicine extract, stand-by,

Embodiment 8:

A kind of compound recipe toon domiphen bromide topical agent, component meter by weight, comprise following composition: toon 225 parts, wild crow Folium toonae sinensis 150 parts, Radix dendrolobii triangularis 160 parts, Pericarpium Citri Reticulatae Viride sets 115 parts, Herba Oxytropis Myriophyllae 120 parts, Radix aconiti sinomontani 45 parts, 35 portions of Platycarya strobilacea, wild flax 80 parts, tree 75 parts, Radix Glycyrrhizae, Radix Ardisiae punctatae 60 parts, Rhizoma et Radix Diphylleiae 70 parts, Ramulus Et Folium Picrasmae root 45 parts, Herba Eguiseti Debilis 90 parts, Rhamnella gilgitica Mansf. Melch. 70 parts, water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 200 parts, Quartz Album 75 parts, spire Herba Moslae Cavaleriei 115 parts, Herba Leontopodii Leontopodioidis 110 parts, the silver back of the body 70 parts, rattan, Herb polygoni Lapathifolii 150 parts, Radix sassafratis 100 parts, Radix Melothriae Heterophyllae 75 parts, Folium zelkovae schneiderianae 120 parts, Herba Thesii Longifolii 90 parts, domiphen bromide 1.85 parts, oxytetracycline 2.25 parts, bacitracin 2.1 parts, dimethyl acetylamide 3.0 parts, antioxidant 2.2 parts, antiseptic 1.5 parts, anti-allergic agent 0.65 part, dispersant 3.75 parts, turn celery 150 parts, 200 parts, birch peach tree, Lindernia ruellioides (Colsm.) Pennell 45 parts, purple stem rib celery 120 parts.

(1) toon is taken by proportioning, wild crow Folium toonae sinensis, Radix dendrolobii triangularis, Pericarpium Citri Reticulatae Viride is set, Herba Oxytropis Myriophyllae, Radix aconiti sinomontani, Platycarya strobilacea, wild flax, tree Radix Glycyrrhizae, Radix Ardisiae punctatae, Rhizoma et Radix Diphylleiae, Ramulus Et Folium Picrasmae root, Herba Eguiseti Debilis, Rhamnella gilgitica Mansf. Melch., water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Quartz Album, spire Herba Moslae Cavaleriei, Herba Leontopodii Leontopodioidis, silver back of the body rattan, Herb polygoni Lapathifolii, Radix sassafratis, Radix Melothriae Heterophyllae, Folium zelkovae schneiderianae, Herba Thesii Longifolii, turn celery, birch peach tree, Lindernia ruellioides (Colsm.) Pennell, purple stem rib celery, clean, dry, be ground into 50 order coarse powder, be placed in extraction pot, add the water of 9 times amount, 98.5 DEG C of micro-reflux, extract, 45min that boil, by extracting solution 175 order filter-cloth filterings, adopting thin film evaporation concentrator filtrate to be concentrated into effective ingredient content is 12.5%, obtain Chinese herbal medicine extract, stand-by,

Embodiment 9:

A kind of compound recipe toon domiphen bromide topical agent, component meter by weight, comprise following composition: toon 300 parts, wild crow Folium toonae sinensis 200 parts, Radix dendrolobii triangularis 200 parts, Pericarpium Citri Reticulatae Viride sets 150 parts, Herba Oxytropis Myriophyllae 150 parts, Radix aconiti sinomontani 60 parts, 50 portions of Platycarya strobilacea, wild flax 100 parts, tree 100 parts, Radix Glycyrrhizae, Radix Ardisiae punctatae 80 parts, Rhizoma et Radix Diphylleiae 100 parts, Ramulus Et Folium Picrasmae root 60 parts, Herba Eguiseti Debilis 120 parts, Rhamnella gilgitica Mansf. Melch. 90 parts, water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 250 parts, Quartz Album 90 parts, spire Herba Moslae Cavaleriei 150 parts, Herba Leontopodii Leontopodioidis 150 parts, the silver back of the body 100 parts, rattan, Herb polygoni Lapathifolii 200 parts, Radix sassafratis 150 parts, Radix Melothriae Heterophyllae 100 parts, Folium zelkovae schneiderianae 150 parts, Herba Thesii Longifolii 120 parts, domiphen bromide 2.5 parts, oxytetracycline 2.5 parts, bacitracin 2.4 parts, dimethyl acetylamide 4.0 parts, antioxidant 3.4 parts, antiseptic 2.5 parts, anti-allergic agent 1.0 parts, dispersant 5.5 parts, turn celery 200 parts, 250 parts, birch peach tree, Lindernia ruellioides (Colsm.) Pennell 60 parts, purple stem rib celery 150 parts.

(1) toon is taken by proportioning, wild crow Folium toonae sinensis, Radix dendrolobii triangularis, Pericarpium Citri Reticulatae Viride is set, Herba Oxytropis Myriophyllae, Radix aconiti sinomontani, Platycarya strobilacea, wild flax, tree Radix Glycyrrhizae, Radix Ardisiae punctatae, Rhizoma et Radix Diphylleiae, Ramulus Et Folium Picrasmae root, Herba Eguiseti Debilis, Rhamnella gilgitica Mansf. Melch., water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Quartz Album, spire Herba Moslae Cavaleriei, Herba Leontopodii Leontopodioidis, silver back of the body rattan, Herb polygoni Lapathifolii, Radix sassafratis, Radix Melothriae Heterophyllae, Folium zelkovae schneiderianae, Herba Thesii Longifolii, turn celery, birch peach tree, Lindernia ruellioides (Colsm.) Pennell, purple stem rib celery, clean, dry, be ground into 60 order coarse powder, be placed in extraction pot, add the water of 10 times amount, 99 DEG C of micro-reflux, extract, 50min that boil, by extracting solution 200 order filter-cloth filterings, adopting thin film evaporation concentrator filtrate to be concentrated into effective ingredient content is 15%, obtain Chinese herbal medicine extract, stand-by,

Embodiment 10:

A kind of compound recipe toon domiphen bromide topical agent, component meter by weight, comprise following composition: toon 150 parts, wild crow Folium toonae sinensis 100 parts, Radix dendrolobii triangularis 120 parts, Pericarpium Citri Reticulatae Viride sets 80 parts, Herba Oxytropis Myriophyllae 90 parts, Radix aconiti sinomontani 30 parts, 20 portions of Platycarya strobilacea, wild flax 60 parts, tree 50 parts, Radix Glycyrrhizae, Radix Ardisiae punctatae 40 parts, Rhizoma et Radix Diphylleiae 40 parts, Ramulus Et Folium Picrasmae root 30 parts, Herba Eguiseti Debilis 60 parts, Rhamnella gilgitica Mansf. Melch. 50 parts, water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 150 parts, Quartz Album 60 parts, spire Herba Moslae Cavaleriei 80 parts, Herba Leontopodii Leontopodioidis 70 parts, the silver back of the body 40 parts, rattan, Herb polygoni Lapathifolii 100 parts, Radix sassafratis 50 parts, Radix Melothriae Heterophyllae 50 parts, Folium zelkovae schneiderianae 90 parts, Herba Thesii Longifolii 60 parts, domiphen bromide 1.2 parts, oxytetracycline 2.0 parts, bacitracin 1.8 parts, dimethyl acetylamide 2.0 parts, antioxidant 1.0 parts, antiseptic 0.5 part, anti-allergic agent 0.3 part, dispersant 2.0 parts, turn celery 100 parts, 150 parts, birch peach tree, Lindernia ruellioides (Colsm.) Pennell 30 parts, purple stem rib celery 90 parts, Cor Gigeriae Galli 7 60 parts, Herba Violae arcuatae 60 parts.

(1) toon is taken by proportioning, wild crow Folium toonae sinensis, Radix dendrolobii triangularis, Pericarpium Citri Reticulatae Viride is set, Herba Oxytropis Myriophyllae, Radix aconiti sinomontani, Platycarya strobilacea, wild flax, tree Radix Glycyrrhizae, Radix Ardisiae punctatae, Rhizoma et Radix Diphylleiae, Ramulus Et Folium Picrasmae root, Herba Eguiseti Debilis, Rhamnella gilgitica Mansf. Melch., water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Quartz Album, spire Herba Moslae Cavaleriei, Herba Leontopodii Leontopodioidis, silver back of the body rattan, Herb polygoni Lapathifolii, Radix sassafratis, Radix Melothriae Heterophyllae, Folium zelkovae schneiderianae, Herba Thesii Longifolii, turn celery, birch peach tree, Lindernia ruellioides (Colsm.) Pennell, purple stem rib celery, Cor Gigeriae Galli seven, Herba Violae arcuatae, clean, dry, be ground into 40 order coarse powder, be placed in extraction pot, add the water of 8 times amount, 98 DEG C of micro-reflux, extract, 40min that boil, by extracting solution 150 order filter-cloth filterings, adopting thin film evaporation concentrator filtrate to be concentrated into effective ingredient content is 10%, obtain Chinese herbal medicine extract, stand-by,

Embodiment 11:

A kind of compound recipe toon domiphen bromide topical agent, component meter by weight, comprise following composition: toon 225 parts, wild crow Folium toonae sinensis 150 parts, Radix dendrolobii triangularis 160 parts, Pericarpium Citri Reticulatae Viride sets 115 parts, Herba Oxytropis Myriophyllae 120 parts, Radix aconiti sinomontani 45 parts, 35 portions of Platycarya strobilacea, wild flax 80 parts, tree 75 parts, Radix Glycyrrhizae, Radix Ardisiae punctatae 60 parts, Rhizoma et Radix Diphylleiae 70 parts, Ramulus Et Folium Picrasmae root 45 parts, Herba Eguiseti Debilis 90 parts, Rhamnella gilgitica Mansf. Melch. 70 parts, water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 200 parts, Quartz Album 75 parts, spire Herba Moslae Cavaleriei 115 parts, Herba Leontopodii Leontopodioidis 110 parts, the silver back of the body 70 parts, rattan, Herb polygoni Lapathifolii 150 parts, Radix sassafratis 100 parts, Radix Melothriae Heterophyllae 75 parts, Folium zelkovae schneiderianae 120 parts, Herba Thesii Longifolii 90 parts, domiphen bromide 1.85 parts, oxytetracycline 2.25 parts, bacitracin 2.1 parts, dimethyl acetylamide 3.0 parts, antioxidant 2.2 parts, antiseptic 1.5 parts, anti-allergic agent 0.65 part, dispersant 3.75 parts, turn celery 150 parts, 200 parts, birch peach tree, Lindernia ruellioides (Colsm.) Pennell 45 parts, purple stem rib celery 120 parts, Cor Gigeriae Galli 7 80 parts, Herba Violae arcuatae 75 parts.

(1) toon is taken by proportioning, wild crow Folium toonae sinensis, Radix dendrolobii triangularis, Pericarpium Citri Reticulatae Viride is set, Herba Oxytropis Myriophyllae, Radix aconiti sinomontani, Platycarya strobilacea, wild flax, tree Radix Glycyrrhizae, Radix Ardisiae punctatae, Rhizoma et Radix Diphylleiae, Ramulus Et Folium Picrasmae root, Herba Eguiseti Debilis, Rhamnella gilgitica Mansf. Melch., water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Quartz Album, spire Herba Moslae Cavaleriei, Herba Leontopodii Leontopodioidis, silver back of the body rattan, Herb polygoni Lapathifolii, Radix sassafratis, Radix Melothriae Heterophyllae, Folium zelkovae schneiderianae, Herba Thesii Longifolii, turn celery, birch peach tree, Lindernia ruellioides (Colsm.) Pennell, purple stem rib celery, Cor Gigeriae Galli seven, Herba Violae arcuatae, clean, dry, be ground into 50 order coarse powder, be placed in extraction pot, add the water of 9 times amount, 98.5 DEG C of micro-reflux, extract, 45min that boil, by extracting solution 175 order filter-cloth filterings, adopting thin film evaporation concentrator filtrate to be concentrated into effective ingredient content is 12.5%, obtain Chinese herbal medicine extract, stand-by,

Embodiment 12:

A kind of compound recipe toon domiphen bromide topical agent, component meter by weight, comprise following composition: toon 300 parts, wild crow Folium toonae sinensis 200 parts, Radix dendrolobii triangularis 200 parts, Pericarpium Citri Reticulatae Viride sets 150 parts, Herba Oxytropis Myriophyllae 150 parts, Radix aconiti sinomontani 60 parts, 50 portions of Platycarya strobilacea, wild flax 100 parts, tree 100 parts, Radix Glycyrrhizae, Radix Ardisiae punctatae 80 parts, Rhizoma et Radix Diphylleiae 100 parts, Ramulus Et Folium Picrasmae root 60 parts, Herba Eguiseti Debilis 120 parts, Rhamnella gilgitica Mansf. Melch. 90 parts, water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 250 parts, Quartz Album 90 parts, spire Herba Moslae Cavaleriei 150 parts, Herba Leontopodii Leontopodioidis 150 parts, the silver back of the body 100 parts, rattan, Herb polygoni Lapathifolii 200 parts, Radix sassafratis 150 parts, Radix Melothriae Heterophyllae 100 parts, Folium zelkovae schneiderianae 150 parts, Herba Thesii Longifolii 120 parts, domiphen bromide 2.5 parts, oxytetracycline 2.5 parts, bacitracin 2.4 parts, dimethyl acetylamide 4.0 parts, antioxidant 3.4 parts, antiseptic 2.5 parts, anti-allergic agent 1.0 parts, dispersant 5.5 parts, turn celery 200 parts, 250 parts, birch peach tree, Lindernia ruellioides (Colsm.) Pennell 60 parts, purple stem rib celery 150 parts, Cor Gigeriae Galli 7 100 parts, Herba Violae arcuatae 90 parts.

(1) toon is taken by proportioning, wild crow Folium toonae sinensis, Radix dendrolobii triangularis, Pericarpium Citri Reticulatae Viride is set, Herba Oxytropis Myriophyllae, Radix aconiti sinomontani, Platycarya strobilacea, wild flax, tree Radix Glycyrrhizae, Radix Ardisiae punctatae, Rhizoma et Radix Diphylleiae, Ramulus Et Folium Picrasmae root, Herba Eguiseti Debilis, Rhamnella gilgitica Mansf. Melch., water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Quartz Album, spire Herba Moslae Cavaleriei, Herba Leontopodii Leontopodioidis, silver back of the body rattan, Herb polygoni Lapathifolii, Radix sassafratis, Radix Melothriae Heterophyllae, Folium zelkovae schneiderianae, Herba Thesii Longifolii, turn celery, birch peach tree, Lindernia ruellioides (Colsm.) Pennell, purple stem rib celery, Cor Gigeriae Galli seven, Herba Violae arcuatae, clean, dry, be ground into 60 order coarse powder, be placed in extraction pot, add the water of 10 times amount, 99 DEG C of micro-reflux, extract, 50min that boil, by extracting solution 200 order filter-cloth filterings, adopting thin film evaporation concentrator filtrate to be concentrated into effective ingredient content is 15%, obtain Chinese herbal medicine extract, stand-by,

Clinical practice typical case:

1, Zhao so-and-so, female, 39 years old, people from Shandong, suffer from vagina white macula more than a year, the frequent pruritus of pudendum is abnormal, has pain once in a while, finds on inspection, its pudendum has not shaping white patch, and local skin is nonelastic, and dimness is frosted, after using 1 course for the treatment of of pharmaceutical treatment of the present invention, pruritus and pain symptom disappear completely, after 2 courses for the treatment of, white macula also disappears, and illing skin recovers ruddy gradually, after 3 courses for the treatment of, after testing, return to one's perfect health, and prognosis bona.

2, Song, female, 44 years old, people from Shandong, suffers from vagina white macula a year and a half, the initial stage, pudendum has pruritus once in a while, does not treat in time, after more serious, even with pain, whenever acute pruritus, can unconsciously scratch, cause redness, there is not shaping white patch in pudendum, local skin is nonelastic, slowly occurs breach.After using 1 course for the treatment of of pharmaceutical treatment of the present invention, pruritus and pain symptom disappear completely, and after 2 courses for the treatment of, white patch also disappears, and breach heals gradually, and after 3 courses for the treatment of, illing skin recovers normal gradually, after testing, returns to one's perfect health, and prognosis bona.

3, the summer so-and-so, female, 42 years old, people from Shandong, suffers from vagina white macula more than 2 years, the initial stage, pudendal pruritus, there is not shaping white patch in local, and more serious, with pain, scratch due to during pruritus, cause redness, chap, ulcer, do not treat in time, cause skin lesion expand hardening, thicken, surperficial keratinization, coarse, in pearl white, vaginal hemorrhage.After using 1 course for the treatment of of pharmaceutical treatment of the present invention, pruritus and pain symptom disappear completely, and vagina has no hemorrhage, after 2 courses for the treatment of, white patch also disappears, and breach heals gradually, after 3 courses for the treatment of, illing skin surface keratinization is thinning, come off, recover normal gradually, after 4 courses for the treatment of, return to one's perfect health, and prognosis bona.

4, so-and-so is visitd, female, 38 years old, people from Shandong, suffers from vagina white macula more than 2 years, the initial stage, pudendal pruritus, there is not shaping white patch in local, with pain, scratch due to during pruritus, cause redness, chap, take a turn for the better gradually by after use western medicine, but prognosis mala, occur again crack and ulcer, disease damage district expands, and causes colpitis.After using 1 course for the treatment of of pharmaceutical treatment of the present invention, red and swollen, symptom of chapping took a turn for the better, after 2 courses for the treatment of, white patch also disappears, crack and ulcer are good, and after 3 courses for the treatment of, illing skin surface keratinization is thinning, come off, recover normal gradually, vaginitis also takes a turn for the better, after 4 courses for the treatment of, vagina white macula and vaginitis all return to one's perfect health, and prognosis bona.

Last it is noted that above embodiment is only in order to illustrate technical scheme of the present invention, be not intended to limit; Although with reference to previous embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that: it still can be modified to the technical scheme described in previous embodiment, or carries out equivalent replacement to wherein portion of techniques feature; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of embodiment of the present invention technical scheme.

Claims

1. a compound recipe toon domiphen bromide topical agent, is characterized in that, by weight component meter, comprises following composition: toon 150 ~ 300 parts, wild crow Folium toonae sinensis 100 ~ 200 parts, Radix dendrolobii triangularis 120 ~ 200 parts, 80 ~ 150 parts, Pericarpium Citri Reticulatae Viride tree, Herba Oxytropis Myriophyllae 90 ~ 150 parts, Radix aconiti sinomontani 30 ~ 60 parts, 20 ~ 50 portions of Platycarya strobilacea, wild flax 60 ~ 100 parts, tree 50 ~ 100 parts, Radix Glycyrrhizae, Radix Ardisiae punctatae 40 ~ 80 parts, Rhizoma et Radix Diphylleiae 40 ~ 100 parts, Ramulus Et Folium Picrasmae root 30 ~ 60 parts, Herba Eguiseti Debilis 60 ~ 120 parts, Rhamnella gilgitica Mansf. Melch. 50 ~ 90 parts, water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 150 ~ 250 parts, Quartz Album 60 ~ 90 parts, spire Herba Moslae Cavaleriei 80 ~ 150 parts, Herba Leontopodii Leontopodioidis 70 ~ 150 parts, the silver back of the body 40 ~ 100 parts, rattan, Herb polygoni Lapathifolii 100 ~ 200 parts, Radix sassafratis 50 ~ 150, Radix Melothriae Heterophyllae 50 ~ 100 parts, Folium zelkovae schneiderianae 90 ~ 150 parts, Herba Thesii Longifolii 60 ~ 120 parts, domiphen bromide 1.2 ~ 2.5 parts, oxytetracycline 2.0 ~ 2.5 parts, bacitracin 1.8 ~ 2.4 parts, dimethyl acetylamide 2.0 ~ 4.0 parts, antioxidant 1.0 ~ 3.4 parts, antiseptic 0.5 ~ 2.5 part, anti-allergic agent 0.3 ~ 1.0 part, dispersant 2.0 ~ 5.5 parts.

2. a kind of compound recipe toon domiphen bromide topical agent as claimed in claim 1, is characterized in that, by weight component meter, also comprises following composition: turn celery 100 ~ 200 parts, 150 ~ 250 parts, birch peach tree.

3. a kind of compound recipe toon domiphen bromide topical agent as claimed in claim 1, is characterized in that, by weight component meter, also comprises following composition: Lindernia ruellioides (Colsm.) Pennell 30 ~ 60 parts, purple stem rib celery 90 ~ 150 parts.

4. a kind of compound recipe toon domiphen bromide topical agent as claimed in claim 1, is characterized in that, by weight component meter, also comprises following composition: Cor Gigeriae Galli 7 60 ~ 100 parts, Herba Violae arcuatae 60 ~ 90 parts.

5. a kind of compound recipe toon domiphen bromide topical agent as claimed in claim 1, it is characterized in that, described antioxidant is nimbecetin.

6. a kind of compound recipe toon domiphen bromide topical agent as claimed in claim 1, it is characterized in that, described antiseptic is potassium sorbate.

7. a kind of compound recipe toon domiphen bromide topical agent as claimed in claim 1, it is characterized in that, described anti-allergic agent is that monarch of benzene.

8. a kind of compound recipe toon domiphen bromide topical agent as claimed in claim 1, it is characterized in that, described dispersant is Macrogol 200 or PEG400.

9. a kind of compound recipe toon domiphen bromide topical agent as described in claim 1 or 8, it is characterized in that, preparation method is as follows: