CN105147294A

CN105147294A - Device for measuring sizes of body surface tumors or limbs

Info

Publication number: CN105147294A
Application number: CN201510519244.5A
Authority: CN
Inventors: 贺欣; 樊赛军
Original assignee: Institute of Radiation Medicine of CAMMS
Current assignee: Institute of Radiation Medicine of CAMMS
Priority date: 2015-08-17
Filing date: 2015-08-17
Publication date: 2015-12-16

Abstract

The invention provides a device for measuring sizes of body surface tumors or limbs, and belongs to the field of medical instruments. Aiming to solve the problems that errors of calipers for measuring sizes of body surface tumors or limbs are large, and the sizes of the body surface tumors or the limbs are hard to measure because of abnormal shapes, the invention provides a measuring device based on the principle of a communicating vessel and drainage, the measuring device is simple in structure, can obtain more accurate result with a low cost. The adopted technical essential points are that the equivalent volume of displacement of an object to be measured can be converted in to a container having a smaller internal diameter through a flexible tube according to the principle of a communicating vessel, an accurate measured value can be obtained according to the distance of liquid level changes. The device can be mainly used for measuring intravital animal body surface tumors, animals' or human limbs, animals' tails and various dissected organs. The device is simple in structure, low in cost, resource saving and wide in scope of application.

Description

A kind of device measuring superficial tumor or extremity volume

Technical field

The present invention relates to technical field of medical instruments, be specifically related to the device of measurement superficial tumor needed for a kind of teaching, scientific research, veterinary or extremity.

Background technology

In tumour medicine research and development or oncobiology Mechanism Study, build various tumor model at animal (especially Mus) body surface and applied very general, and individual tumors growth tracking is one of necessary data.The main stream approach that current gross tumor volume measures utilizes kind of calliper tumor major diameter a and minor axis b, and the computing formula of gross tumor volume V is

There is comparatively big error in this method, on the one hand caused by the subjective judgment error measuring people and operate slide calliper rule, because tumor is three-dimensional body on the other hand, the result that the calculating parameter used is two-dimensional measurement mode, not only have ignored the height of tumor, and some tumor shapes irregular (such as Fructus Vitis viniferae shape), usually depart from true larger by the result of vernier caliper measurement.

Setting superficial tumor is the hemispherical of diameter 10mm, sphere volume gross tumor volume should be 261.8mm ³; The result of kind of calliper is: major diameter 10mm, minor axis 10mm, traditionally computing formula gross tumor volume is 500mm ³.The latter is the former 1.9 times.

Although the lesion detection equipment of existing automatization comes out, but equipment, plant maintenance and use cost also significantly increase.

In addition, in structure arthritis model, usually adopt immunogen to stimulate and cause animal (Mus) red swollen feet, by the toes volume after swelling and normal toes volumetric ratio comparatively, as one of the index of degree of inflammation.Current measuring method directly foot is immersed graduated cylinder, toes volume=graduated cylinder internal diameter area × liquid level rise distance, and for mice foot volume, the obvious error of this measuring method is too large.

For the problems referred to above, the present invention proposes a kind of measuring device designed according to law of connected vessels and drainage, structure is simple, obtains measurement result comparatively accurately under can be implemented in low cost, is applicable to the superficial tumor, extremity etc. of measuring animals or humans.

Summary of the invention

The object of this invention is to provide a kind of novel superficial tumor measuring device, it is made up of two parts: measuring vessel and support.As shown in Figure 1, left side is measuring junction, and wherein, 1 is datum line, and before and after measuring, liquid level flushes with datum line all the time: 2 is infundibulate measuring device, and material is glass; Dashed region is expressed as 3, and material is soft pipeline, is convenient to flexible liquid level, ensures that liquid level flushes with datum line; 4 is scale end, is made up of the glass tubing with a scale of uniform diameter, and 2,3,4 is inner UNICOMs; 5 is scale; 6 is common iron stand.

Operation principle of the present invention: according to law of connected vessels, immerses the liquid level of 2 by testee, by regulating flexible pipe 3, make the build-up of fluid of 2 to datum level 1, the equivalent displacement of volume of tested volume be switched to internal diameter less 4, according to the level change Distance geometry sectional area of 4, conversion bulking value.Before measuring, container is fixed on iron stand, add a certain amount of water, liquid level is flushed with datum line 1, and the liquid level of scale end 4 flushes at scale initial point place.Due to law of connected vessels, scale initial point and datum line 1 must be that level is mutually neat, as Fig. 1.During measurement, as shown in Figure 2, firmly animal is caught with hands, ensure that tumor locus fully exposes, tumor be immersed in the water, tumor arranges the water equaling own vol, now, liquid level slightly goes up, slightly move down 4, until liquid level comes back to datum line 1 in measuring junction 2, now, the part that the relative initial point of liquid level that tumor displacement of volume is embodied in glass tubing 4 completely goes up, reading can obtain in 5.Cross-sectional area × liquid level rise the distance of gross tumor volume=glass tubing 4; Or can the bulking value after conversion be labeled on scale, direct reading.

Testee can be the animal body surface tumor of live body, also can be the extremity of animal or human, the tail of animal and the various organs etc. after dissecting.According to the volume range of testee, this device of different size specification can be manufactured, realize coupling.

Measuring junction 2 also can be made into other shapes, not necessarily infundibulate.

Accompanying drawing explanation

Fig. 1 is structural representation of the present invention;

Fig. 2 is that the present invention measures tumor schematic diagram.

Detailed description of the invention

Embodiment one, measurement superficial tumor

Adopt glass tubing 4 internal diameter 5.046mm, cross-sectional area is 20mm ², scale 5 initial point place is 0, and often rising 1mm marks scale 20mm ³.Before measurement, be fixed on iron stand 6 in 2 and 4, add the water of certain volume, make liquid level remain on the scale initial point of datum line 1 and glass tubing 4, two ends in the same horizontal line.Erose for body surface tumor is immersed in measuring junction 2 liquid level, ensures that measuring junction is fixed, move down glass tubing 4 gently, until liquid level comes back to datum line 1.Now in glass tubing 4 liquid level comparatively initial point to have gone up 20mm, corresponding scale is 400mm ³.Conveniently can obtain gross tumor volume value intuitively thus.

Embodiment two, measurement mice toes volume

Adopt glass tubing 4 internal diameter 2.523mm, cross-sectional area is 5mm ², scale 5 initial point place is 0, and often rising 1mm marks scale 5mm ³.Before measurement, be fixed on iron stand 6 in 2 and 4, add the water of certain volume, make liquid level remain on the scale initial point of datum line 1 and glass tubing 4, two ends in the same horizontal line.Mice toes are immersed in measuring junction 2 liquid level, ensures that measuring junction is fixed, move down glass tubing 4 gently, until liquid level comes back to datum line l.Now in glass tubing 4 liquid level comparatively initial point go up to scale be 40mm ³.Conveniently can obtain mice toes volumetric values intuitively thus.

Embodiment three, add electronic equipment realize automatically monitor liquid level

At the datum line l place of 2, fix two minimum sheet metals, the relative position of vertical direction is 0.1mm of being separated by up and down; Sheet metal is connected by power supply, and form electric potential difference, when liquid level position is higher than two sheet metals, water is electric conductor, forms loop, and green display lamp is bright.When regulating the height of glass tubing 4, liquid level declines gradually, and when liquid level is just lower than that higher sheet metal, green indicating lamp goes out.This moment, stop regulating liquid surface height immediately, complete reading.

Claims

1. measure the device of superficial tumor or extremity volume for one kind, be made up of two parts: measuring vessel and support 6, measuring vessel forms a linker by scale end 4 three of measuring junction 2, adjustable flexible pipe 3 and uniform diameter, according to drainage, testee is immersed the liquid level of 2, by regulating flexible pipe 3, make the build-up of fluid of 2 to datum level 1, the equivalent displacement of volume of tested volume be switched to internal diameter less 4, according to the level change Distance geometry sectional area of 4, conversion bulking value.

2. a kind of device measuring superficial tumor or extremity volume according to claim 1, is characterized in that: can add electronic equipment and realize automatically monitoring liquid level.

3. a kind of device measuring superficial tumor or extremity volume according to claim 1, is characterized in that: the measuring vessel that can manufacture different size specification, mates different testee.