CN105126180A - Medical personal lubricant and preparation method thereof - Google Patents
Medical personal lubricant and preparation method thereof Download PDFInfo
- Publication number
- CN105126180A CN105126180A CN201510445411.6A CN201510445411A CN105126180A CN 105126180 A CN105126180 A CN 105126180A CN 201510445411 A CN201510445411 A CN 201510445411A CN 105126180 A CN105126180 A CN 105126180A
- Authority
- CN
- China
- Prior art keywords
- silicone
- glycerol
- oil
- viscosity
- lubricant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000314 lubricant Substances 0.000 title claims abstract description 60
- 238000002360 preparation method Methods 0.000 title abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 26
- 239000008213 purified water Substances 0.000 claims abstract description 21
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 7
- 239000000043 antiallergic agent Substances 0.000 claims abstract description 6
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 179
- 229920001296 polysiloxane Chemical group 0.000 claims description 67
- -1 polyhexamethylene guanidine Polymers 0.000 claims description 28
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 claims description 25
- 229940106189 ceramide Drugs 0.000 claims description 25
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 claims description 25
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 claims description 25
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 claims description 23
- PPWHTZKZQNXVAE-UHFFFAOYSA-N Tetracaine hydrochloride Chemical compound Cl.CCCCNC1=CC=C(C(=O)OCCN(C)C)C=C1 PPWHTZKZQNXVAE-UHFFFAOYSA-N 0.000 claims description 21
- 229960002494 tetracaine hydrochloride Drugs 0.000 claims description 21
- 235000009392 Vitis Nutrition 0.000 claims description 13
- 241000219095 Vitis Species 0.000 claims description 13
- TVQGDYNRXLTQAP-UHFFFAOYSA-N ethyl heptanoate Chemical group CCCCCCC(=O)OCC TVQGDYNRXLTQAP-UHFFFAOYSA-N 0.000 claims description 12
- 239000002994 raw material Substances 0.000 claims description 11
- 235000009508 confectionery Nutrition 0.000 claims description 10
- 238000003756 stirring Methods 0.000 claims description 8
- 230000000844 anti-bacterial effect Effects 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 230000001954 sterilising effect Effects 0.000 claims description 5
- 238000004659 sterilization and disinfection Methods 0.000 claims description 5
- 238000012360 testing method Methods 0.000 claims description 5
- 238000000746 purification Methods 0.000 claims description 3
- 229960002372 tetracaine Drugs 0.000 claims description 3
- 125000001549 ceramide group Chemical group 0.000 claims description 2
- 230000035945 sensitivity Effects 0.000 abstract description 7
- 210000005036 nerve Anatomy 0.000 abstract description 5
- 206010036596 premature ejaculation Diseases 0.000 abstract description 4
- 229940035674 anesthetics Drugs 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 239000003193 general anesthetic agent Substances 0.000 abstract 1
- 230000036449 good health Effects 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 description 48
- 239000003921 oil Substances 0.000 description 28
- 235000019198 oils Nutrition 0.000 description 28
- 210000003899 penis Anatomy 0.000 description 18
- 239000000243 solution Substances 0.000 description 11
- 230000036407 pain Effects 0.000 description 9
- 230000006870 function Effects 0.000 description 8
- 230000000694 effects Effects 0.000 description 6
- 230000001568 sexual effect Effects 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 5
- 238000003780 insertion Methods 0.000 description 4
- 230000037431 insertion Effects 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 230000001537 neural effect Effects 0.000 description 4
- 210000000056 organ Anatomy 0.000 description 4
- 235000006708 antioxidants Nutrition 0.000 description 3
- 238000005461 lubrication Methods 0.000 description 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 206010072353 Painful ejaculation Diseases 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 230000001139 anti-pruritic effect Effects 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 210000001215 vagina Anatomy 0.000 description 2
- FRXSZNDVFUDTIR-UHFFFAOYSA-N 6-methoxy-1,2,3,4-tetrahydroquinoline Chemical compound N1CCCC2=CC(OC)=CC=C21 FRXSZNDVFUDTIR-UHFFFAOYSA-N 0.000 description 1
- 235000019489 Almond oil Nutrition 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 241000193738 Bacillus anthracis Species 0.000 description 1
- 241001478240 Coccus Species 0.000 description 1
- 241000186216 Corynebacterium Species 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 206010061978 Genital lesion Diseases 0.000 description 1
- STECJAGHUSJQJN-GAUPFVANSA-N Hyoscine Natural products C1([C@H](CO)C(=O)OC2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-GAUPFVANSA-N 0.000 description 1
- 241000192041 Micrococcus Species 0.000 description 1
- 241000711386 Mumps virus Species 0.000 description 1
- 235000007265 Myrrhis odorata Nutrition 0.000 description 1
- STECJAGHUSJQJN-UHFFFAOYSA-N N-Methyl-scopolamin Natural products C1C(C2C3O2)N(C)C3CC1OC(=O)C(CO)C1=CC=CC=C1 STECJAGHUSJQJN-UHFFFAOYSA-N 0.000 description 1
- 240000004760 Pimpinella anisum Species 0.000 description 1
- 235000012550 Pimpinella anisum Nutrition 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 description 1
- 206010040007 Sense of oppression Diseases 0.000 description 1
- 241000607762 Shigella flexneri Species 0.000 description 1
- 241000700584 Simplexvirus Species 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 241000191963 Staphylococcus epidermidis Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 241000193990 Streptococcus sp. 'group B' Species 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 206010048222 Xerosis Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000008168 almond oil Substances 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 238000001949 anaesthesia Methods 0.000 description 1
- 230000003444 anaesthetic effect Effects 0.000 description 1
- 230000002804 anti-anaphylactic effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 210000000736 corneocyte Anatomy 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 206010013023 diphtheria Diseases 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000009986 erectile function Effects 0.000 description 1
- 230000002964 excitative effect Effects 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 210000004392 genitalia Anatomy 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 150000002596 lactones Chemical class 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 210000002706 plastid Anatomy 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000007115 recruitment Effects 0.000 description 1
- 230000011514 reflex Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- STECJAGHUSJQJN-FWXGHANASA-N scopolamine Chemical compound C1([C@@H](CO)C(=O)O[C@H]2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-FWXGHANASA-N 0.000 description 1
- 229960002646 scopolamine Drugs 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000004206 stomach function Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Abstract
The invention relates to the technical field of lubricants, in particular to a medical personal lubricant for improvement of male premature ejaculation and a preparation method of the medical personal lubricant. The medical personal lubricant is composed of, by weight, 10%-20% of lubricant, 2%-4% of anesthetics, 0.2%-0.4% of antibacterial agent, 0.15%-0.23% of antioxidant, 0.27%-0.32% of antiallergic agent and the rest of purified water. The medical personal lubricant and the preparation method thereof have the advantages of effectiveness in reduction of nerve sensitivity, assistance in treatment of premature ejaculation to realize time extension, high practicality, healthiness and safety.
Description
Technical field
The present invention relates to technical field of lubricant, particularly relate to a kind of for medical human lubricant improving prospermia of males and preparation method thereof.
Background technology
Along with the development of society, male subjects larger stress in life, work, stress causes more greatly the nerve of male to be often in sensitiveness, even if in love life, male is still difficult to the state of very fast adjustment oneself, usually cause love life to terminate faster, often cause that wife or girl friend's is unhappy; In order to improve love life quality, there is this medicine of many similar viagras on the market, but the lasting use of this medicine, can male body be damaged.
Summary of the invention
The object of the invention is to solve the deficiencies in the prior art, provide a kind of medical human lubricant, this lubricant can reduce the neural sensitivity of male genitals, alleviates the nervous psychology of male; Extend the love life time, and harmless to health.
For achieving the above object, the technical solution used in the present invention is:
A kind of medical human lubricant, is made up of following raw material (weight ratio):
Lubricant 10% ~ 20%
Anesthetis 2% ~ 4%
Sterilization antibacterial 0.2% ~ 0.4%
Antioxidant 0.15% ~ 0.23%
Anti-allergic agent 0.27% ~ 0.32%
Purified water surplus.
Preferably, wherein, lubricant comprises glycerol and silicone, glycerol and silicone part by weight: 1.8 ~ 2.1:1;
Anesthetis comprises tetracaine hydrochloride, Fructus Anisi Stellati oil, Oleum menthae; Its part by weight is followed successively by: 18 ~ 23:7 ~ 12:2.8 ~ 3.1;
Sterilization antibacterial is polyhexamethylene guanidine;
Antioxidant is Oleum Vitis viniferae;
Anti-allergic agent is ceramide.Oleum menthae also plays certain antipruritic effect.
Polyhexamethylene guanidine can produce ionization in aqueous, and its hydrophilic group part contains strong electropositive, and absorption is usually in electronegative each bacterioid, virus, enter cell membrane, suppress the synthesis of film lactone plastid, cause thalline apoptosis, reach best bactericidal effect.
Oleum Vitis viniferae rich in vitamin E, has stronger non-oxidizability.
Ceramide is that the main composition composition being present in lipoid between human body skin outermost corneocyte plays the important function preventing moisture from distributing and outside stimulus is had to safeguard function, carries protection skin and moist, moisture-keeping functions.Xerosis cutis can be prevented irritated.
Oleum menthae has inhibitory action to herpes simplex virus, forest virus, mumps virus, has bacteriostasis to staphylococcus aureus, Staphylococcus albus, alpha streptococcus, group B streptococcus, micrococcus catarrhalis, enteritis coccus, shigella flexneri, anthrax bacillus, diphtheria corynebacterium, Bacillus typhi, bacillus pyocyaneus, escherichia coli etc.; Water solublity Oleum menthae can excite nerve tip cold receptor and produce creeping chill, and reflexive cause the change of deep tissue blood vessel and play antiinflammatory, pain relieving, antipruritic effect.
When love life, the glans penis of lubricant to male organ plays certain lubrication.
Anise is economic tree.Fruit is famous flavoring, and taste is fragrant and sweet.Also hyoscine, having dispels the wind regulates the flow of vital energy, stomach function regulating adjust in function, for invasion by pathogenic cold vomiting, abdominal part cold type of pain, stomach feeling of distension and oppression etc.
Anistree main component is Oleum Anisi Stellati, and its energy stimulating gastrointestinal neural blood vessel, facilitating digestion liquid is secreted, and increases gastrointestinal peristalsis, has effect of stomach invigorating, circulation of qi promoting, contributes to alleviating spasm, easing the pain.
Further, the weight ratio of glycerol is B1, the weight ratio of silicone is B2, corresponding sweet oil viscosity is A1, and the viscosity of the silicone of correspondence is A2, the target viscosities of medical human lubricant is N, 0.04lgN>B1 × lgA1+B2 × lgA2>0.02lgN.Here weight ratio is for whole human body medical lubricant, as B1 represents that glycerol accounts for the weight ratio of whole human body medical lubricant.A1 represents that weight ratio is the viscosity of the glycerine water solution of B1, and A2 represents that weight ratio is the viscosity of the almond oil aqueous solution of B2; Different Weight ratio, its viscosity is different.Viscosity can be obtained by test.
In use, this medical human lubricant, while the effect playing lubrication, also plays certain viscosity effect, and viscosity is too large, and love life can be caused to have some setbacks; The too little then lubricant effect of viscosity is more weak.Therefore at needs balance lubrication and viscosity effect.
Therefore the technical program is when designing, and needs to make the viscosity of redeployed human body medical lubricant in the certain limit of target viscosities.Need to be optimized collocation to the content of glycerol, silicone.
The viscosity of glycerol, silicone is relevant at the percentage by weight of medical human lubricant to it, the viscosity that namely different percentage by weights is corresponding different; The silicone oil of Different Weight percentage ratio and the viscosity of silicone obtain by experiment.Target viscosities can obtain an ideal value by test of many times and obtain; In order to obtain good viscosity, select glycerol proportional components and the silicone ratio composition of coincidence formula 0.04lgN>B1 × lgA1+B2 × lgA2>0.02lgN, after mixing with other compositions, the viscosity of medical human lubricant can reach: 0.8N ~ 1.2N; Meet human body to be suitable for.
Further, a kind of medical human lubricant, is made up of following raw material (weight ratio):
Glycerol 8% ~ 12%
Silicone 4% ~ 6%
Tetracaine hydrochloride 1.7% ~ 2.2%
Fructus Anisi Stellati oil 0.9% ~ 1.1%
Polyhexamethylene guanidine 0.28% ~ 0.33%
Oleum Vitis viniferae 0.18% ~ 0.21%
Ceramide 0.28% ~ 0.31%
Oleum menthae 0.28% ~ 0.31%
Purified water surplus.
Again further, a kind of medical human lubricant, is made up of following raw material (weight ratio):
Glycerol 10%
Silicone 5%
Tetracaine hydrochloride 2%
Fructus Anisi Stellati oil 1%
Polyhexamethylene guanidine 0.3%
Oleum Vitis viniferae 0.2%
Ceramide 0.3%
Oleum menthae 0.3%
Purified water surplus.
The mechanism of action: glycerol, silicone are to male organ's glans penis lubricate; Tetracaine hydrochloride, Oleum menthae, Fructus Anisi Stellati oil play surface anesthetic effect to glans penis, and alleviate the neural sensitivity degree of glans penis, extending sex time, and Oleum menthae also has itching-relieving action; Polyhexamethylene guanidine plays the antibacterial effect of sterilization; Ceramide plays antianaphylactic effect; The young oil of Fructus Vitis viniferae plays antioxidative effect.
Prepare a method for medical human lubricant, comprising:
Step 1, join get formula ratio glycerol, silicone, tetracaine hydrochloride, polyhexamethylene guanidine, ceramide, Fructus Vitis viniferae young oil, Oleum menthae, Fructus Anisi Stellati oil and purified water;
Step 2, in agitator, pour 70 ~ 90% of the purification water yield into, then pour tetracaine hydrochloride, polyhexamethylene guanidine, ceramide, Fructus Vitis viniferae young oil, Oleum menthae, Fructus Anisi Stellati oil successively into;
Step 3, silicone are poured in glycerol, and stir until silicone is dissolved in glycerol, form organic solution;
Step 4, organic solution is poured in agitator; Then remaining purified water is poured into.
Prepare a method for medical human lubricant, comprising:
Step 1, join and get (weight ratio) 10 parts of glycerol, 5 parts of silicone, 2 parts of tetracaine hydrochlorides, 0.3 part of polyhexamethylene guanidine, 0.3 part of ceramide, 0.2 part of young oil of Fructus Vitis viniferae, 0.3 part of Oleum menthae, 1 part of Fructus Anisi Stellati oil;
Step 2, in agitator, pour 78 parts of purified water into, then pour into successively in step 1 join get tetracaine hydrochloride, polyhexamethylene guanidine, ceramide, Fructus Vitis viniferae young oil, Oleum menthae, Fructus Anisi Stellati oil;
Step 3,4 parts of silicone to be poured in the glycerol of 8 parts, and stir until silicone is dissolved in glycerol, form organic solution;
Step 4, organic solution to be poured in agitator.
In step 5, test agitator, the viscosity of mixed liquor, if viscosity is less than 90% of target viscosities, then continues progressively to increase remaining glycerol, silicone in agitator; Until viscosity is 90% ~ 110% of target viscosities.
Beneficial effect of the present invention is:
1), the combination of glycerol and acetone, reach good lubricant effect; Reduce friction, reduce the stimulation degree to male organ; Simultaneously modest viscosity, can be more permanent be attached on male organ surface, use comfortable.
2), coordinate the anesthetis of trace to use, reduced by the sensitivity of Sensitive nerve, light anaesthesia glans penis is neural; Extend reflex time.
3), antioxidant, anti-allergic agent is added; Avoid skin allergy, lubricant oxidation.
Detailed description of the invention
Below the present invention is described further.
Embodiment 1:
A kind of medical human lubricant, is made up of following raw material (weight ratio):
Glycerol 8% ~ 8.5%
Silicone 5.5% ~ 6%
Tetracaine hydrochloride 1.7%
Fructus Anisi Stellati oil 0.9%
Polyhexamethylene guanidine 0.28%
Oleum Vitis viniferae 0.21%
Ceramide 0.28%
Oleum menthae 0.28%
Purified water surplus.
Preferably, the kind of glycerol, silicone is chosen and quality, and the viscosity according to target is chosen, make lubricant meet human body the viscosity that is suitable for; In low concentration, the viscosity of glycerol, silicone and content linearly ratio, the weight ratio of glycerol is B1, and the weight ratio of silicone is B2, and sweet oil viscosity is A1, and the viscosity of silicone is A2, A1=K1 × B1, A2=K2 × B2; When the target viscosities of medical human lubricant is N, meet 0.04lgN>B1 × lgA1+B2 × lgA2>0.02lgN, 90% ~ 110% of target viscosities can be reached, meet instructions for use, this formula can be expressed as further: 0.04lgN>B1 × lg(K1 × B1)+B2 × lg(K2 × B2) >0.02lgN.K1, K2 can pass through many experiments, carry out line segment function matching acquisition to data.And the scope of B1, B2 has provided, multiple combination can be calculated by formula.During calculating, one of them parameter B1 or B2 can be selected.Target viscosities is 5mpas, and e.g., 25 degree, 8% sweet oil viscosity is 20mpas, and the viscosity of 6% silicone is 50mpas; 0.04lgN=0.28,0.02lgN=0.14,8% × lg20+6% × lg50=0.206.The glycerol of 8%, the silicone of 6% can be selected in the present embodiment.
The medical human lubricant viscosity that the present embodiment mixes is meeting in scope.
Case 1:
Huang, man, 45 years old, penis insertion intravaginal was ejaculated in 1 minute and with painful ejaculation, is adopted the present invention, and penis inserts intravaginal and continues sex time at 3 ~ 6 minutes, alleviates sensitivity, sexual life satisfaction.
Embodiment 2:
A kind of medical human lubricant, is made up of following raw material (weight ratio):
Glycerol 11.5% ~ 12%
Silicone 4% ~ 4.5%
Tetracaine hydrochloride 2.2%
Fructus Anisi Stellati oil 1.1%
Polyhexamethylene guanidine 0.33%
Oleum Vitis viniferae 0.18%
Ceramide 0.31%
Oleum menthae 0.31%
Purified water surplus.
Preferably, the kind of glycerol, silicone is chosen and quality, and the viscosity according to target is chosen, make lubricant meet human body the viscosity that is suitable for; In low concentration, the viscosity of glycerol, silicone and content linearly ratio, the weight ratio of glycerol is B1, and the weight ratio of silicone is B2, and sweet oil viscosity is A1, and the viscosity of silicone is A2, A1=K1 × B1, A2=K2 × B2; When the target viscosities of medical human lubricant is N, meet 0.04lgN>B1 × lgA1+B2 × lgA2>0.02lgN, 90% ~ 110% of target viscosities can be reached, meet instructions for use, this formula can be expressed as further: 0.04lgN>B1 × lg(K1 × B1)+B2 × lg(K2 × B2) >0.02lgN.K1, K2 can pass through many experiments, carry out line segment function matching acquisition to data.And the scope of B1, B2 has provided, multiple combination can be calculated by formula.During calculating, one of them parameter B1 or B2 can be selected.As, target viscosities is 5mpas, 25 degree, and 12% sweet oil viscosity is 25mpas, and the viscosity of 4% silicone is 30mpas; 0.04lgN=0.28,0.02lgN=0.14,12% × lg25+4% × lg30=0.227.12% glycerol, 4% silicone can be chosen in the present embodiment.The medical human lubricant viscosity that the present embodiment mixes is meeting in scope.
Case 2
Zhang, man, 39 years old, penis inserted vagina with pain, and after erection, namely a contact cysthus ejaculates, and adopts the present invention, alleviates sensitivity, and penis inserts intravaginal and continues sex time at 2 ~ 5 minutes, and sexual life is satisfied.
Embodiment 3:
A kind of medical human lubricant, is made up of following raw material (weight ratio):
Glycerol 10% ~ 10.5%
Silicone 5.0% ~ 5.5%
Tetracaine hydrochloride 1.8%
Fructus Anisi Stellati oil 1.1%
Polyhexamethylene guanidine 0.31%
Oleum Vitis viniferae 0.19%
Ceramide 0.3%
Oleum menthae 0.29%
Purified water surplus.
Preferably, the kind of glycerol, silicone is chosen and quality, and the viscosity according to target is chosen, make lubricant meet human body the viscosity that is suitable for; In low concentration, the viscosity of glycerol, silicone and content linearly ratio, the weight ratio of glycerol is B1, and the weight ratio of silicone is B2, and sweet oil viscosity is A1, and the viscosity of silicone is A2, A1=K1 × B1, A2=K2 × B2; When the target viscosities of medical human lubricant is N, meet 0.04lgN>B1 × lgA1+B2 × lgA2>0.02lgN, 90% ~ 110% of target viscosities can be reached, meet instructions for use, this formula can be expressed as further: 0.04lgN>B1 × lg(K1 × B1)+B2 × lg(K2 × B2) >0.02lgN.K1, K2 can pass through many experiments, carry out line segment function matching acquisition to data.And the scope of B1, B2 has provided, multiple combination can be calculated by formula.During calculating, one of them parameter B1 or B2 can be selected.As, target viscosities is 5mpas, 25 degree, and 10% sweet oil viscosity is 22mpas, and the viscosity of 5% silicone is 40mpas; 0.04lgN=0.28,0.02lgN=0.14,10% × lg22+5% × lg40=0.273.10% glycerol, 5% silicone can be chosen in the present embodiment.The medical human lubricant viscosity that the present embodiment mixes, meeting in scope, adapts to human body and uses.
Case 3
Lin, man, 55 years old, penis insertion intravaginal was ejaculated in 1 minute, even with pain bleeding, adopted the present invention to alleviate pain, and penis inserts intravaginal and continues sex time at 2 ~ 4 minutes.
Embodiment 4:
A kind of medical human lubricant, is made up of following raw material (weight ratio):
Glycerol 9% ~ 9.5%
Silicone 4.5% ~ 5%
Tetracaine hydrochloride 1.9%
Fructus Anisi Stellati oil 1.0%
Polyhexamethylene guanidine 0.3%
Oleum Vitis viniferae 0.21%
Ceramide 0.31%
Oleum menthae 0.31%
Purified water surplus.
Preferably, the kind of glycerol, silicone is chosen and quality, and the viscosity according to target is chosen, make lubricant meet human body the viscosity that is suitable for; In low concentration, the viscosity of glycerol, silicone and content linearly ratio, the weight ratio of glycerol is B1, and the weight ratio of silicone is B2, and sweet oil viscosity is A1, and the viscosity of silicone is A2, A1=K1 × B1, A2=K2 × B2; When the target viscosities of medical human lubricant is N, meet 0.04lgN>B1 × lgA1+B2 × lgA2>0.02lgN, 90% ~ 110% of target viscosities can be reached, meet instructions for use, this formula can be expressed as further: 0.04lgN>B1 × lg(K1 × B1)+B2 × lg(K2 × B2) >0.02lgN.K1, K2 can pass through many experiments, carry out line segment function matching acquisition to data.And the scope of B1, B2 has provided, multiple combination can be calculated by formula.During calculating, one of them parameter B1 or B2 can be selected.As 9% glycerol, 5% silicone can be chosen in the present embodiment.The medical human lubricant viscosity that the present embodiment mixes is meeting in scope.
Case 4
Lee, man, 45 years old, penis insertion intravaginal was ejaculated in 2 minutes, even with pain bleeding, adopted the present invention to alleviate pain, and penis inserts intravaginal and continues sex time at 5 ~ 6 minutes.
Embodiment 5:
A kind of medical human lubricant, is made up of following raw material (weight ratio):
Glycerol 10%
Silicone 5%
Tetracaine hydrochloride 2%
Fructus Anisi Stellati oil 1%
Polyhexamethylene guanidine 0.3%
Oleum Vitis viniferae 0.2%
Ceramide 0.3%
Oleum menthae 0.3%
Purified water surplus.
The viscosity of the human body lubricants that this ratio coordinates is about 4.8mpas, and the suitability is good.
Clinical trial:
Case 5
Zhang, man, 39 years old, penis inserted vagina with pain, and after erection, namely a contact cysthus ejaculates, and adopts the present invention, alleviates sensitivity, and penis inserts intravaginal and continues sex time at 2 ~ 5 minutes, and sexual life is satisfied.
Product for embodiment 1-5 carries out clinical trial, Guangxi Grade A hospital reproduction section, male patient 31 example, 20 ~ 60 years old age, wherein after 11 routine main suits erection, namely a contact cysthus ejaculates, 20 routine main suits penises insertion intravaginal was ejaculated in 1 minute, and in 31 routine patients, 3 examples are with symptoms such as painful ejaculations.Health check-up: penile erectile function is normal, without obvious genital lesion, impassivity systemic disease history, main cause is the responsive too fast problem entering excitatory state of glans penis cutaneous nerve.Carry out tracking treatment to these 31 patients, effective percentage reaches 96.7%(and cures 23 people, and take a turn for the better 7 people).Cure: penis inserts intravaginal and continues sex time more than 3 minutes, and sexual life is satisfied; Take a turn for the better: sometimes can continue within sexual intercourse 2-3 minute, sometimes still premature ejaculation; Invalid: to continue sexual intercourse within 1 minute, still premature ejaculation.
Embodiment 6: a kind of method preparing the arbitrary medical human lubricant of embodiment 1-5, comprising:
Step 1, join get formula ratio glycerol, silicone, tetracaine hydrochloride, polyhexamethylene guanidine, ceramide, Fructus Vitis viniferae young oil, Oleum menthae, Fructus Anisi Stellati oil and purified water;
Step 2, in agitator, pour 70 ~ 90% of the purification water yield into, then pour tetracaine hydrochloride, polyhexamethylene guanidine, ceramide, Fructus Vitis viniferae young oil, Oleum menthae, Fructus Anisi Stellati oil successively into;
Step 3, silicone are poured in glycerol, and stir until silicone is dissolved in glycerol, form organic solution;
Step 4, organic solution is poured in agitator; Then pour remaining purified water into, stir.
Embodiment 7: a kind of method preparing medical human lubricant, comprising:
Step 1, join and get (weight ratio) 10 parts of glycerol, 5 parts of silicone, 2 parts of tetracaine hydrochlorides, 0.3 part of polyhexamethylene guanidine, 0.3 part of ceramide, 0.2 part of young oil of Fructus Vitis viniferae, 0.3 part of Oleum menthae, 1 part of Fructus Anisi Stellati oil;
Step 2, in agitator, pour 78 parts of purified water into, then pour into successively in step 1 join get tetracaine hydrochloride, polyhexamethylene guanidine, ceramide, Fructus Vitis viniferae young oil, Oleum menthae, Fructus Anisi Stellati oil;
Step 3,4 parts of silicone to be poured in the glycerol of 8 parts, and stir until silicone is dissolved in glycerol, form organic solution;
Step 4, organic solution to be poured in agitator.
In step 5, test agitator, the viscosity of mixed liquor, if viscosity is less than 90% of target viscosities, then continues progressively to increase remaining glycerol, silicone in agitator; And stir, until viscosity is 90% ~ 110% of target viscosities.
In step 5, can first glycerol adding, after add silicone; Each recruitment is at 0.1 part.
Below be only the preferred embodiment of the application, equivalent technical solutions on this basis still falls into application protection domain.
Claims (7)
1. a medical human lubricant, is characterized in that: be made up of following raw material (weight ratio):
Lubricant 10% ~ 20%
Anesthetis 2% ~ 4%
Sterilization antibacterial 0.2% ~ 0.4%
Antioxidant 0.15% ~ 0.23%
Anti-allergic agent 0.27% ~ 0.32%
Purified water surplus.
2. a kind of medical human lubricant according to claim 1, is characterized in that:
Wherein, lubricant comprises glycerol and silicone, glycerol and silicone part by weight: 1.8 ~ 2.1:1;
Anesthetis comprises tetracaine hydrochloride, Fructus Anisi Stellati oil, Oleum menthae; Its part by weight is followed successively by: 18 ~ 23:7 ~ 12:2.8 ~ 3.1;
Sterilization antibacterial is polyhexamethylene guanidine;
Antioxidant is Oleum Vitis viniferae;
Anti-allergic agent is ceramide.
3. a kind of medical human lubricant according to claim 2, is characterized in that:
The weight ratio of glycerol is B1, the weight ratio of silicone is B2, and corresponding sweet oil viscosity is A1, and the viscosity of silicone is A2, the target viscosities of medical human lubricant is N, 0.04lgN>B1 × lgA1+B2 × lgA2>0.02lgN.
4. a kind of medical human lubricant according to claim 2, is characterized in that:
Be made up of following raw material (weight ratio):
Glycerol 8% ~ 12%
Silicone 4% ~ 6%
Tetracaine hydrochloride 1.7% ~ 2.2%
Fructus Anisi Stellati oil 0.9% ~ 1.1%
Polyhexamethylene guanidine 0.28% ~ 0.33%
Oleum Vitis viniferae 0.18% ~ 0.21%
Ceramide 0.28% ~ 0.31%
Oleum menthae 0.28% ~ 0.31%
Purified water surplus.
5. a kind of medical human lubricant according to claim 4, is characterized in that:
Be made up of following raw material (weight ratio):
Glycerol 10%
Silicone 5%
Tetracaine hydrochloride 2%
Fructus Anisi Stellati oil 1%
Polyhexamethylene guanidine 0.3%
Oleum Vitis viniferae 0.2%
Ceramide 0.3%
Oleum menthae 0.3%
Purified water surplus.
6. prepare a method for medical human lubricant as described in claim 4 or 5, it is characterized in that: comprising:
Step 1, join get formula ratio glycerol, silicone, tetracaine hydrochloride, polyhexamethylene guanidine, ceramide, Fructus Vitis viniferae young oil, Oleum menthae, Fructus Anisi Stellati oil and purified water;
Step 2, in agitator, pour 70 ~ 90% of the purification water yield into, then pour tetracaine hydrochloride, polyhexamethylene guanidine, ceramide, Fructus Vitis viniferae young oil, Oleum menthae, Fructus Anisi Stellati oil successively into;
Step 3, silicone are poured in glycerol, and stir until silicone is dissolved in glycerol, form organic solution;
Step 4, organic solution is poured in agitator, then pour remaining purified water into.
7. prepare a method for medical human lubricant, it is characterized in that: comprising:
Step 1, join and get (weight ratio) 10 parts of glycerol, 5 parts of silicone, 2 parts of tetracaine hydrochlorides, 0.3 part of polyhexamethylene guanidine, 0.3 part of ceramide, 0.2 part of young oil of Fructus Vitis viniferae, 0.3 part of Oleum menthae, 1 part of Fructus Anisi Stellati oil;
Step 2, in agitator, pour 78 parts of purified water into, then pour into successively in step 1 join get tetracaine hydrochloride, polyhexamethylene guanidine, ceramide, Fructus Vitis viniferae young oil, Oleum menthae, Fructus Anisi Stellati oil;
Step 3,4 parts of silicone to be poured in the glycerol of 8 parts, and stir until silicone is dissolved in glycerol, form organic solution;
Step 4, organic solution is poured in agitator;
In step 5, test agitator, the viscosity of mixed liquor, if viscosity is less than 90% of target viscosities, then continues progressively to increase remaining glycerol, silicone in agitator; Until viscosity is 90% ~ 110% of target viscosities.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510445411.6A CN105126180B (en) | 2015-07-27 | 2015-07-27 | A kind of medical human lubricant and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510445411.6A CN105126180B (en) | 2015-07-27 | 2015-07-27 | A kind of medical human lubricant and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105126180A true CN105126180A (en) | 2015-12-09 |
| CN105126180B CN105126180B (en) | 2018-06-01 |
Family
ID=54711977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510445411.6A Active CN105126180B (en) | 2015-07-27 | 2015-07-27 | A kind of medical human lubricant and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105126180B (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004313285A1 (en) * | 2003-12-16 | 2005-09-29 | Foamix Ltd | Oleaginous pharmaceutical and cosmetic foam |
| CN103271839A (en) * | 2013-06-20 | 2013-09-04 | 上海西宝生物科技有限公司 | Skin care composition and application thereof |
| CN103933621A (en) * | 2014-04-16 | 2014-07-23 | 广西信业生物技术有限公司 | Medical lubricant and preparation method thereof |
| CN104784761A (en) * | 2015-03-27 | 2015-07-22 | 桂林恒保健康用品有限公司 | Personal lubricant added with modified silicone oil |
-
2015
- 2015-07-27 CN CN201510445411.6A patent/CN105126180B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004313285A1 (en) * | 2003-12-16 | 2005-09-29 | Foamix Ltd | Oleaginous pharmaceutical and cosmetic foam |
| CN103271839A (en) * | 2013-06-20 | 2013-09-04 | 上海西宝生物科技有限公司 | Skin care composition and application thereof |
| CN103933621A (en) * | 2014-04-16 | 2014-07-23 | 广西信业生物技术有限公司 | Medical lubricant and preparation method thereof |
| CN104784761A (en) * | 2015-03-27 | 2015-07-22 | 桂林恒保健康用品有限公司 | Personal lubricant added with modified silicone oil |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105126180B (en) | 2018-06-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Boericke | Homeophatic Materia Medica | |
| US8668913B2 (en) | Complementary personal lubricant compositions | |
| CN106466454A (en) | A kind of prevention and the gel for the treatment of gynecological inflammation | |
| CN106727849A (en) | A kind of gynecological gel | |
| CN103961556A (en) | Dendrobium officinale oculentum for relieving asthenopia | |
| WO2013175504A2 (en) | Herbal composition for vaginal treatment | |
| JP4558479B2 (en) | Therapeutic 1,2,3,6-tetrahydropyrimidin-2-one composition and method using the same | |
| Kent | New remedies, clinical cases, lesser writings, aphorisms and precepts | |
| CN106552078A (en) | A kind of multifunctional biological agent | |
| WO2015174712A1 (en) | Contraceptive device for men | |
| CN103877288B (en) | A kind of chitosan nasopharynx biological medicinal membrane and preparation method thereof | |
| KR101870227B1 (en) | Natural sterilization composition for cooling skin heat | |
| CN105126180A (en) | Medical personal lubricant and preparation method thereof | |
| CN1965912B (en) | Application of Chinese medicine polygala root as in-vitro spermaticide and method for preparing the medicament thereof | |
| CN104941010B (en) | A kind of Medical vagina lubricating fluid and preparation method thereof | |
| CN114028318B (en) | Male antibacterial liquid and preparation method and application thereof | |
| CN103830666B (en) | One treats hypertensive Chinese lavipeditum composition | |
| Shreeve | The alternative dictionary of symptoms and cures | |
| CN101313966B (en) | Medicament for treating asphyxia | |
| WO2000010559A1 (en) | Inorgasmia treatment | |
| CN103893297A (en) | Traditional Chinese medicine ointment for treating nasosinusitis | |
| Evers | Remarks on Ignipedites | |
| KR20200070684A (en) | A medicated plaster | |
| Hargreaves | A Practical Manual of Venereal Diseases: Including Disorders of Generation, Spermatorrhoea, Prostatorrhoea, Impotence and Sterility in Both Sexes | |
| Rowden | A case of descending Landry's paralysis in a child |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20151209 Assignee: GUANGXI DAQING BIOLOGICAL SCIENCE & TECHNOLOGY CO.,LTD. Assignor: GUANGXI XINYE BIOLOGICAL TECHNOLOGY Co.,Ltd. Contract record no.: X2023980043782 Denomination of invention: A medical human lubricant and its preparation method Granted publication date: 20180601 License type: Common License Record date: 20231018 |
|
| EE01 | Entry into force of recordation of patent licensing contract |