CN105107044A - Blood purifier - Google Patents
Blood purifier Download PDFInfo
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- CN105107044A CN105107044A CN201510561208.5A CN201510561208A CN105107044A CN 105107044 A CN105107044 A CN 105107044A CN 201510561208 A CN201510561208 A CN 201510561208A CN 105107044 A CN105107044 A CN 105107044A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3672—Means preventing coagulation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3687—Chemical treatment
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Biomedical Technology (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
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- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- External Artificial Organs (AREA)
Abstract
The invention discloses a blood purifier, which comprises a cylindrical shell and filter screens at two end sides of the cylindrical shell; an adsorbent accommodating chamber is set between the filter screens at two end sides; and the ratio of the axial length of the adsorbent accommodating chamber and the maximum diameter is 2.5-4.0. By adopting the adsorbent accommodating chamber in the radio of the length and the diameter, the blood purifier is more accord with the characteristics of blood flowing; phenomenon like blind angle and eddy current can be prevented; the blood can pass through the blood purifier in a short time; and the risk of blood clotting during blood perfusion can be reduced. The cylindrical shell is made integrated preferably; the blood inlet end employs a trumpet-shaped guiding part; the bubble in a perfusion device can be exhausted rapidly at a pre-punching; the exhaust time can be shortened; and the pre-punching operation can be simplified.
Description
Technical field
The present invention relates to blood purification consumptive material field, particularly a kind of apparatus for purifying blood.
Background technology
Along with progress and the development of blood perfusion technique, its scope of application is more and more wider, and treatment category has related to multiple fields such as drug intoxication, uremia, kidney disease, disease of immune system.Along with the raising of people's living standard and the increase of health perception, hemoperfusion, as a kind of disease treatment mode, is widely accepted, and annual use amount is in the trend increased.
As the medical apparatus and instruments being exclusively used in blood purification, apparatus for purifying blood is built-in with the adsorbent purified the blood.In Clinical practice process, apparatus for purifying blood is series at extracorporeal circulation of blood pipeline, when blood is through apparatus for purifying blood, and the morbid substance in adsorbent blood wherein, thus reach the object of disease therapy.
Chinese utility model patent CN200820047979 discloses a kind of disposable blood perfusion device, and the component parts of this perfusion device comprises a cylindrical shell and the two cover closing devices for the axial two-port of difference sealed cylinder.In inner barrel, various types of adsorbent can be held according to different therapeutic purposes, such as acticarbon, resin sorbent etc.Often overlap closing device to be made up of filter screen, sealing plain cushion, end cap, locking nut and block etc.End cap is arranged at the end of cylindrical shell, end cap has blood mouth, and block coordinates with the blood mouth on end cap, thus realizes the sealing to blood mouth and perfusion device.Wherein, cylindrical shell, end cap, locking nut and block all adopt medical Merlon to produce with Shooting Technique as raw material; Sealing plain cushion and the sealed bolster be fixed on block all adopt silicone rubber to produce with Shooting Technique as raw material; Filter screen is normally produced with weaving manner as raw material with nylon yarn.Content disclosed in above-mentioned patent is incorporated to by reference to quoting herein.
Due to blood flow mechanics characteristic, apparatus for purifying blood inside of the prior art has vertical dead angle, blood may be caused to produce eddy current, reduce blood flowing speed, cause blood coagulation to produce, add patient's application risk.And when rushing in advance, the gas of apparatus for purifying blood inside is not easily discharged, increase and rush operation easier in advance, extend and rush the time in advance.On the other hand due in prior art, for guaranteeing the sealing of apparatus for purifying blood, the bonding force between block and end cap is excessive, cause medical personnel use apparatus for purifying blood before cannot open block, thus make product operation degree of comfort decreased.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of apparatus for purifying blood more meeting blood flow dynamics, to strengthen the mobility of blood in apparatus for purifying blood inside.
In order to solve the problems of the technologies described above, the invention provides a kind of apparatus for purifying blood, comprise cylindrical shell and the filter screen being positioned at this cylindrical shell both end sides, described have adsorbent containment chamber between the filter screen of both end sides, and the axial length in described adsorbent containment chamber and the ratio of its maximum gauge are 2.5-4.0.Described filter screen is positioned at cylindrical shell both end sides, refers to and is positioned near barrel end, both can be the inside being positioned at barrel end, also can be the outside being positioned at barrel end.
Apparatus for purifying blood of the present invention has the adsorbent containment chamber of above-mentioned draw ratio by adopting, it meets blood flowing characteristic more, dead angle, vortex phenomenon can be prevented, blood can be allowed in the short period of time by apparatus for purifying blood, reduce the risk that blood coagulation occurs when hemoperfusion patient.
Further, described cylindrical shell tapered and have blood flow into end and blood outflow end, described blood outflow end is the opening end that diameter is larger, the diameter that described blood flows into end is less, this blood flows into end and comprises guide portion, limiting platform and blood mouth, wherein said guide portion is horn-like, and the tapering of this horn-like guide portion is 25-45 °; Described limiting platform is between described guide portion and described blood mouth, and this limiting platform is connected with the less one end of the diameter of this horn-like guide portion.Above-mentioned cylindrical shell adopts unitary design, and its blood flows into end and adopts horn-like guide portion, and bubble when contributing to rushing in advance in perfusion device is discharged fast, shortens evacuation time, simplifies and rushes operation in advance.
In one embodiment, described apparatus for purifying blood can also comprise flowing into described blood to be held and/or end cap that blood outflow end is connected, described end cap comprises the lid, blood mouth and the limiting platform between described lid and blood mouth that are connected, described lid is horn-like, described blood mouth is near the less one end of the diameter of this horn-like lid, and the tapering of described horn-like lid is 25-45 °.
Further, filter screen is provided with between the respective end of described end cap and described cylindrical shell, described filter screen comprises rack and mesh sheet, described rack is roughly in hollow round table shape, it comprises the supporting walls as round platform end face and the guiding wall as frustum cone side, one end that described supporting walls is less with described guiding wall diameter is connected, and described mesh sheet is fixed on described supporting walls, and the tapering of the guiding wall of described rack is substantially identical with the tapering of described horn-like lid.
Further, the diameter of effective filtration zone of described mesh sheet is 6mm-20mm.Effective filter diameter like this makes this filter screen be more prone to aerofluxus, can significantly reduce medical care labor intensity.
Further, described rack also comprises the circular mounting flange that one end larger with described guiding wall diameter is connected, and this mounting flange extends along the radial direction of described rack; Described filter screen is positioned between the respective end of described end cap and described cylindrical shell by this mounting flange, the supporting walls of described rack and closely cooperating near its blood mouth one end of described end cap, guiding wall and the described horn-like lid of described rack fit tightly, the axis of described mesh sheet and the dead in line of described blood mouth.
In one embodiment, the inside of described limiting platform has the filter screen installation position being formed as cylindrical cavity, and be provided with filter screen in the middle of this filter screen installation position, described filter screen comprises rack and mesh sheet.
Further, the two ends of this apparatus for purifying blood are equipped with described filter screen and corresponding filter screen installation position, connected by support bar between two groups of filter screens, the internal chamber wall of described filter screen installation position and the outer wall of described rack are shiny surface, described outer wall and described internal chamber wall fit tightly, the axial inner ends face of described rack is provided with support slot, and the end of described support bar coordinates with described support slot grafting, thus makes described filter screen be fixed on described filter screen installation position.
As other embodiments, the internal chamber wall of described filter screen installation position is provided with the buckle or female thread that are suitable for coordinating with described filter screen, and the rack of described filter screen is provided with corresponding locating slot or external screw thread.
Further, described blood flow into end and/or blood outflow end be provided with can with the external screw thread of the screw-internal thread fit on nut or end cap, described externally threaded end is provided with for preventing the notch opened, and described notch can match with the Unclosing structure that prevents on described nut or end cap.Said structure can prevent because nut or end cap loosen the risk of leakage of generation.
Further, described cylindrical shell is provided with adsorbent loading prompting mark.
Accompanying drawing explanation
Fig. 1 a is the structural representation of the embodiment one of apparatus for purifying blood of the present invention.
Fig. 1 b is the sectional view of apparatus for purifying blood shown in Fig. 1 a.
Fig. 2 is the longitudinal sectional view of the block in apparatus for purifying blood shown in Fig. 1.
The horizontal partial sectional view that Fig. 3 is the block in apparatus for purifying blood shown in Fig. 1.
Fig. 4 is the end cap sectional view in apparatus for purifying blood shown in Fig. 1.
Fig. 5 is the upward view of the filter screen in the middle of apparatus for purifying blood shown in Fig. 1.
Fig. 6 is the A-A sectional view of Fig. 5.
Fig. 7 is the top view of the filter screen in the middle of apparatus for purifying blood shown in Fig. 1.
Fig. 8 is the side view of the filter screen in the middle of apparatus for purifying blood shown in Fig. 1.
Fig. 9 is the sectional view of the cylindrical shell in apparatus for purifying blood shown in Fig. 1.
Figure 10 is the transverse sectional view of the nut in apparatus for purifying blood shown in Fig. 1.
Figure 11 is the longitudinal sectional view of the embodiment two of apparatus for purifying blood of the present invention.
The structural representation that Figure 12 is the filter screen in the middle of apparatus for purifying blood shown in Figure 11 and support bar.
Figure 13 is the upward view of the filter screen in the middle of apparatus for purifying blood shown in Figure 11.
Figure 14 is the D-D sectional view of Figure 13.
Figure 15 is the longitudinal sectional view of the embodiment four of apparatus for purifying blood of the present invention.
Figure 16 is the top view of the filter screen in the middle of apparatus for purifying blood shown in Figure 15.
Figure 17 is the B-B sectional view of Figure 16.
Figure 18 is the cylindrical shell plane graph of the embodiment five of apparatus for purifying blood of the present invention.
Figure 19 is the sectional view of cylindrical shell shown in Figure 18.
Figure 20 is the top view of the sealing ring in the middle of the embodiment six of apparatus for purifying blood of the present invention.
The C-C sectional view that Figure 21 is sealing ring shown in Figure 20.
Detailed description of the invention
To describe various embodiment of the present invention below in detail, embodiment wherein in conjunction with the accompanying drawings and describe hereinafter.Although the present invention will be described in conjunction with illustrative embodiments, be to be understood that and the invention is not restricted to these illustrative embodiments.On the contrary, the present invention not only comprises these embodiments, but also comprises various distortion, improvement.
Embodiment one
As illustrated in figs. ia and ib, the apparatus for purifying blood of the present embodiment can be the inner apparatus for purifying blood that accommodate adsorbent such as single use blood perfusion device, single use plasma bilirubin adsorber, single use Endotoxin adsorption device, DNA immunization adsorber.Apparatus for purifying blood in the present embodiment is single use blood perfusion device, it filter screen 14 comprising cylindrical shell 18 and be positioned at cylindrical shell 18 both end sides, between the filter screen 14 of both end sides, there is adsorbent containment chamber 20, various types of adsorbent can be held according to different therapeutic purposes, the such as agent of natural polymer carrier adsorption, acticarbon, resin sorbent etc. in this adsorbent containment chamber 20.Described filter screen 14 is positioned at the both end sides of cylindrical shell 18, refer to be positioned at cylindrical shell 18 end near, both can be the inside being positioned at barrel end, also can be the outside being positioned at barrel end.The lower end of cylindrical shell 18 is female Luer and Luer lock joint, is sealed by block 10.Press seal is carried out by sealing ring 17, end cap 13 and nut 16 in the upper end of cylindrical shell 18, wherein, end cap 13 is sealed by block 10, nut 16 and cylindrical shell 18 end are connected with screw thread or click on fashion and coordinate, the filter screen installation position 138 for installing fixing filter screen 14 is provided with in end cap 13, preferably, filter screen installation position 138 is arranged at the gateway place near end cap 13.Block 10 comprises block body 11 and sealed bolster 12, block body 11 can be hard plastic part, such as adopt medical polycarbonate or polypropylene PP to produce with Shooting Technique as raw material, sealed bolster 12 and sealing ring 17 can adopt silicone rubber to produce with Shooting Technique as raw material.
As shown in Figures 2 and 3, block 10 comprises block body 11 and sealed bolster 12, described block body 11 comprises perisporium 21, end wall 22 and hollow joint pin 23, and axial one end of wherein said perisporium 21 is formed as opening 29 of blocking a shot, and the axial other end is closed by described end wall 22.
Described perisporium 21 is cylindrical shape, its outer circumference is 40mm, the outer peripheral face of perisporium 21 is provided with three antislip cogs 24, interval arc length between each antislip cog is 7-13mm, for 1/4 to 2/3 of the last joint length of human finger, if the outer circumference change of perisporium 21, then can set the antislip cog 24 of varying number according to the size of this outer circumference, thus the human body operational comfort that increase block 10 is opened or covered.Finger mainly contacts with the smooth part on the outer peripheral face of perisporium 21, makes the utilization rate of the power of operator higher by the thrust between finger and antislip cog 24.The uniform wall thickness of perisporium 21, preferably, part corresponding to antislip cog 24 on the inner peripheral surface of perisporium 21 is formed with corresponding sunk structure 211.The phenomenon adopting the perisporium 21 of uniform wall thickness to contribute to reducing stress to concentrate, avoids concentrating due to stress and the defects such as the crackle that causes.
Described perisporium 21 is provided with outward flange 25 near one end of block opening 29, and the bottom of outward flange 25 is provided with multiple anti-slip tank 26; Along the axis direction of perisporium 21, the cross section of described anti-slip tank 26 is trapezoidal, and the larger bottom of length contacts with the limiting platform 132 on end cap 13, and the upper base that length is less coordinates with the top of the floating-point 135 on limiting platform 132.Preferably, the axial cross section of anti-slip tank 26 is isosceles trapezoid, and the angle of base and waist is 45 °.Anti-slip tank 26 is arranged to this shape, when block 10 is turned on from blood mouth 131, trapezoidal side can reduce the frictional force between floating-point 135 and anti-slip tank 26, contribute to guiding floating-point 135 to be separated with anti-slip tank 26, thus avoid the adhesion of blocking a shot between 10 and blood mouth 131 in prior art to cause too greatly the problem of twisting not open.
Described hollow joint pin 23 is from radial middle part axially the extending towards described block opening 29 along described perisporium 21 of end wall 22, this hollow joint pin 23 is formed as lumen openings near one end of block opening 29, inner wall surface thereof is provided with three protruding spacing fins 27, described spacing fin 27 is for increasing frictional force between hollow joint pin 23 and sealed bolster 12, and provide the deformation space of sealed bolster 12 under impaction state, can prevent sealed bolster 12 from coming off from block body 11 and being pressed on blood mouth 131.In addition, the outer peripheral face of hollow joint pin 23 is also provided with external screw thread 28.Described sealed bolster 12 is arranged on the inner side near end wall 22 of hollow joint pin 23.
Above-mentioned block 10 structure is simple, antislip cog 24 set by perisporium 21 outer peripheral face meets human engineering, be conducive to that normal person is free-hand easily to be opened it, easy to operate, the respective recesses structure that on perisporium 21 inner peripheral surface, the part corresponding with antislip cog 24 is formed can discharge the internal stress that Merlon (PC) material produces in injection moulding process effectively.The spacing fin 27 that hollow joint pin 23 inner peripheral surface of block 10 is arranged can increase the friction with sealed bolster 22, and provide the deformation space of sealed bolster 22 under impaction state, can prevent sealed bolster 22 from coming off from block body 11 and being pressed on blood mouth 131.Anti-slip tank 26 adopts special vibrational power flow, thus solves in prior art the problem of not opening of blocking a shot.
End cap 13 in the present embodiment is split type end cap, and pre-determined bit is first carried out in end cap 13 and cylindrical shell 18 end, then is realized being fixedly connected with of cylindrical shell 18 and end cap 13 by nut 16 and the screw thread couple of cylindrical shell 18 end.In other embodiments, above-mentioned end cap can also be integral type end cap, and namely end cap is provided with coupled threads integratedly, barrel end is also provided with coupled threads, end cap is fixedly connected with by screw thread couple with cylindrical shell.
As shown in Fig. 1 b and Fig. 4, this end cap 13 comprises blood mouth 131, limiting platform 132 and the lid 133 etc. that are connected, limiting platform 132 between blood mouth 131 and lid 133, for limiting the amount of coupling between block 10 with end cap 13.This limiting platform 132 inside has filter screen installation position 138.The outer of blood mouth 131 is arranged with cylindric coupled wall 136, and this coupled wall 136 has identical axis with blood mouth 131, and the inner peripheral surface of coupled wall 136 is provided with the female thread 137 that can be coupled with the external screw thread 28 of hollow joint pin 23.In the present embodiment, the female thread 137 on coupled wall 136 is double thread, and this double thread left and right length is respectively the isosceles trapezoid of 1.6mm, 1.0mm, and Double helix angle is 30 °.Blood mouth 131 is Rule male joint, and Rule male joint is in mating connection with the outer union joint with standard luer taper, thus ensure that the popularity on this end cap Clinical practice.Blood mouth 131 and limiting platform 132 and lid 133 one-body molded, adopt medical grade material to obtain with injection molding manner, to ensure the safety in use procedure.Filter screen installation position 138 is cylindrical cavity, and diameter can be 20mm, and the chamber wall of this filter screen installation position 138 is provided with buckle 1381, for fixed support filter screen 14.
Lid 133 is in horn-like, and its tapering can be 25 ° to 45 °, such as, be 30 °, and the less one end of its diameter is near filter screen installation position 138.Blood mouth 131 is inserted into the inner chamber of the hollow joint pin 23 of block 10, and the outer end of blood mouth 131 is sealed by sealed bolster 12.The end face of limiting platform 132 is provided with the multiple floating-points 135 around coupled wall 136, and in the present embodiment, the quantity of floating-point 135 is preferably 6.Floating-point 135 shape is hemispherical or other shapes be applicable to, and diameter can be 0.8mm.When the outward flange 25 of block 10 contacts with limiting platform 132, floating-point 135 on limiting platform 132 coordinates with the anti-slip tank 26 on block 10, preferably, anti-slip tank 26 is identical with the quantity of floating-point 135, one_to_one corresponding coordinates, thus plays locking effect to block 10, avoids block 10 to be opened easily in non-artificial situation or under less External Force Acting, guarantee safety, avoid the harmful substances such as antibacterial to enter blood mouth 131.The periphery of one end that the diameter of lid 133 is larger is provided with coupling loop 1310, for coordinating with the end of perfusion device cylindrical shell 18, guide ring 1311 is provided with at the intersection of coupling loop 1310 and lid 133, guide ring 1311 for limiting the internal diameter of sealing ring 17, thus realizes the control to sealing ring 17 decrement.
As shown in Fig. 5 to Fig. 8, filter screen 14 comprises rack 142 and mesh sheet 141, and rack 142 is the cylindrical of inner chamber hollow, and mesh sheet 141 is preferably fixed on the upper end of rack 142 with bonding mode, this set is more conducive to the bonding operation of mesh sheet 141.The diameter of effective filtration zone of mesh sheet 141 can be 6-20mm, in the present embodiment, the diameter of effective filtration zone of filter screen is 11mm, the outer wall of rack 142 is provided with L-shaped locating slot, the first paragraph 143 of this locating slot extends along the axis of rack 142, and the circumferencial direction of second segment 144 at the axially middle part of rack 142 outer wall along rack 142 extends.The head end of the first paragraph 143 of this locating slot is the opening of the upper surface (being namely bonded with the surface of mesh sheet 141) being positioned at rack 142, and the tail end of first paragraph 143 is connected with the head end of second segment 144, and the tail end of second segment 144 is blind end.
The inner chamber 145 of rack 142 be provided with guide surface 146 away from mesh sheet 141 one end, be convenient to guide blood enter rack 142 and flow out perfusion device by mesh sheet 141, rack internal chamber wall is provided with several installing holes 1410, for coordinating with fixture filter screen 14 is installed on perfusion device.Buckle 1381 on chamber, filter screen installation position 138 wall in limiting platform 132 coordinates with " L " shape locating slot on rack 142, is fixed on limiting platform 132 by filter screen 14 with coordinating of buckle 1381 by " L " shape locating slot.
As shown in Figure 9, the cylindrical shell 18 in the present embodiment is integral type cylindrical shell, and this cylindrical shell 18 is overall tapered.The cylindrical shell 18 of this taper has the larger blood outflow end 181 of diameter and the less blood of diameter flows into end 182.Wherein blood outflow end 181 is cylindrical opening end.Blood is outside from this blood outflow end 181 outflow tube 18, and the end face of blood outflow end 181 is provided with sealing ring mounting groove 183, to place sealing ring 17, by the height of adjustment sealing ring mounting groove 183, can control the decrement of sealing ring 17.The outer wall of blood outflow end 181 is provided with external screw thread 1811, for nut 16(or integral type end cap) on female thread be coupled.
As shown in Figure 10, nut 16 inwall in the present embodiment is provided with two screw thread and non-return buckle 162, two screw thread is coupled with the external screw thread 1811 of cylindrical shell 18 end, and non-return fastener 162 for engaging with the anti-notch of opening of external screw thread 1811 end, thus realizes the anti-opening function of perfusion device.Non-return buckle 162 angle on nut 16 inwall is 7.5 °.The outer wall of nut 16 is provided with anti-roll boss 163, causes damaging for preventing from tumbling when perfusion device is put in plane, also can be used as the location snap-in structure of nut 16 when installing perfusion device simultaneously, is convenient to nut and is positioned on sectional fixture.Anti-roll boss 163 for radius be the circular arc of 4mm.Match at the end of the cylindrical shell 18 end external screw thread 1811 non-return buckle 162 had on screw thread two with nut 16 inwall and realize cylindrical shell 18 and prevent by the notch again opened after being in place with end cap 13, nut 16, avoid perfusion device after dispatching from the factory, use before be opened and make the gnotobasis of perfusion device inside contaminated, thus avoid unnecessary treatment potential safety hazard.Described notch can be arranged at external screw thread 1811 end and be parallel on the direction of cylindrical shell 18 diameter, or is parallel on the direction of cylindrical shell 18 axis.The outer wall of cylindrical shell 18 is provided with nut screwing clamping and puts in place sign 185 near end, nut 16(or integral type end cap) be provided with the sign 161 that puts in place accordingly, instruction production exercise workmanship is by nut 16(or integral type end cap) and cylindrical shell 18 between install and be screwed to position, or prevented from twisting, guaranteed the installation qualification rate of perfusion device.
When the blood outflow end 181 of cylindrical shell 18 is connected with end cap 13, first sealing ring 17 is placed on the guide ring 1311 on end cap 13, then end cap 13 is coordinated with the blood outflow end 181 of cylindrical shell 18, sealing ring 17 is made to be positioned at sealing ring mounting groove 183, realize the pre-determined bit of end cap 13 and cylindrical shell 18, the external screw thread 1811 flowing out end finally by nut 16 and the blood of cylindrical shell 18 is coupled, until the non-return buckle 162 in nut engages with the anti-notch of opening of barrel end male ends, realize the fixing seal of cylindrical shell 18 and end cap 13.
In addition, the outer wall of the blood outflow end 181 of cylindrical shell 18 is provided with adsorbent loading amount indicatrix 1812, for pointing out the installation of adsorbent, avoids adsorbent installation too much or very few.
The blood inflow end 182 that the diameter of cylindrical shell 18 is less comprises integrated guide portion 186, limiting platform 187 and blood mouth 188, and this guide portion 186 is in horn-like.Larger one end of diameter of guide portion 186 is connected with the main body of cylindrical shell 18, and the less one end of diameter is connected with limiting platform 187.The tapering of horn-like guide portion 186 can be 25 °-45 °, such as, be 30 °.
In the present embodiment, the axial length in adsorbent containment chamber 20 and the ratio (i.e. the draw ratio in adsorbent containment chamber 20) of its maximum gauge are 2.5-4.0, such as, be 3.0.The adsorbent containment chamber with this draw ratio can meet blood flowing characteristic more, and blood can be allowed in the short period of time by apparatus for purifying blood, reduces the risk that blood coagulation occurs when hemoperfusion patient.
Limiting platform 187 is cylindric, inside has filter screen installation position 1871, this filter screen installation position 1871 is cylindrical cavity, the diameter of this cylindrical cavity can be 20mm, chamber wall is provided with the buckle or screw thread 1872 that are suitable for coordinating with filter screen, thus filter screen 14(is shown in Fig. 1) be fixed on filter screen installation position 1871.Limiting platform 187 is provided with the anti-skidding floating-point 1873 around blood mouth 188 near the end face of blood mouth 188, anti-skidding floating-point 1873 can be hemispherical or other suitable shapes, diameter is 0.8mm, quantity is 6, anti-skidding floating-point 1873 coordinates with the anti-slip tank 26 of the bottom of outward flange 25 on block 10, block 11 is played to the function of self-locking.
Cylindrical shell 18 outer wall being provided with blood mouth 188 one end is provided with three anti-skidding ribs 189, is convenient to pre-determined bit when perfusion device is installed.
Embodiment two
As shown in Figure 11 to 14, the apparatus for purifying blood of this embodiment is DNA immunization adsorber, connected by support bar 19 between the filter screen 14 at its cylindrical shell two ends, filter screen 14 is fixed on limiting platform 132 and 187, this filter screen 14 comprises rack 142 and mesh sheet 141 equally, and the diameter of effective filtration zone of mesh sheet 141 is 15mm.Wherein, the internal chamber wall of limiting platform 132 and 187 is shiny surface, the outer wall 147 of the rack 142 of filter screen 14 is also smooth surface, the outer wall of rack 142 and the internal chamber wall of limiting platform 132 and 187 fit tightly, the axial inner ends face of rack 142 is provided with support slot 149, the end of support bar 19 coordinates with support slot 149 grafting on the rack 142 of the filter screen 14 at DNA immunization adsorption column two ends, thus filter screen 14 is fixed on the inside of DNA immunization adsorption column.In addition, support bar 19 also connects by bracing piece 191 and strengthens the intensity of support bar, avoids support bar generation elastic deformation, ensures that the installation site of filter screen is fixed, guarantees the effective barrier effect of filter screen to adsorbent.
Embodiment three
In the present embodiment, the structure of blood perfusion device is substantially identical with embodiment one, and difference is, the axial length in the adsorbent containment chamber of the present embodiment and the ratio of its maximum gauge are 2.5, and the lid tapering of end cap is 45 °.The chamber wall of filter screen installation position is provided with female thread, and the rack of filter screen is provided with external screw thread, and fixed by the form of screw thread couple between filter screen and filter screen installation position, effective filtration zone diameter of filter screen is 6mm.
Embodiment four
As Figure 15, in the present embodiment, the structure of blood perfusion device is substantially identical with embodiment one, difference is mainly the structure of filter screen 14, and the axial length in the adsorbent containment chamber 20 of this blood perfusion device and the ratio of its maximum gauge are 3.2, and the tapering of the lid 133 of end cap 13 is 30 °.
As shown in Figure 16 and Figure 17, filter screen 14 comprises rack 142 and mesh sheet 141, wherein rack 142 is roughly in hollow round table shape, and it comprises comparatively large as supporting walls 143, the horn-like guiding wall 144 as side and the diameter as bottom surface that the diameter of end face is less and is circular mounting flange 145.The tapering of horn-like guiding wall 144 is substantially identical with the tapering of the lid 133 of end cap 13, and this tapering can be 25 °-45 °, is preferably 30 °.Mesh sheet 141 is such as fixed on supporting walls 143 by the mode of bonding, and the diameter of effective filtration zone of this mesh sheet can be 6mm-20mm, is preferably 11mm.One end that mounting flange 145 is larger with guiding wall 144 diameter is connected, and extends certain distance along the radial direction of rack 142.Filter screen 14 is arranged between the end of cylindrical shell 18 and end cap 13 by mounting flange 145, thus realizes the location of filter screen 14.
When filter screen 14 is installed in the middle of perfusion device, the supporting walls 143 of rack 142 closely cooperates with close blood mouth 131 one end of end cap 13, and the horn-like guiding wall 144 of rack 142 fits tightly with the horn-like lid 133 of end cap 13.Along the axis direction of perfusion device, the axis of mesh sheet 141 and the dead in line of blood mouth 131, namely directly enter the cylindrical shell 18 of perfusion device by mesh sheet 141 after liquid enters perfusion device from blood mouth 131 inner, and the supporting walls 143 of rack 142, guiding wall 144 and the close-fitting position of end cap 13 can not be entered.Preferably, rack 142 has certain elastic rack for meeting rigidity requirement simultaneously.When liquid or gas will discharge perfusion device from perfusion device inside, the guiding wall 144 first along rack 142 enters mesh sheet 141, then discharges perfusion device by blood mouth 131.
Embodiment five
In the present embodiment, the structure of blood perfusion device is substantially identical with embodiment three, and difference is, the tapering of the horn-like guiding wall of filter screen and the tapering of end cap lid are 25 °, and the diameter of effective filtration zone of mesh sheet is 15mm.
Embodiment six
As shown in Figure 18 and Figure 19, the cylindrical shell 28 of the present embodiment blood perfusion device is cylindrical, and its two ends are opening, and the periphery wall of two ends is provided with external screw thread 281, for being coupled with the female thread on end cap or on nut.External screw thread 281 end of barrel end be provided with match with nut for preventing the notch 282 opened, the outer wall of cylindrical shell 28 is provided with nut screwing clamping and puts in place sign 283 and adsorbent loading amount indicatrix 285.The adsorbent containment chamber 286(of cylindrical shell 28 does not comprise the following filter screen mounting groove 284 mentioned) axial length and the ratio of its maximum gauge be 3.0, two ends of cylindrical shell 28 are provided with filter screen mounting groove 284, for carrying out pre-determined bit to filter screen, filter screen coordinates with sealing ring, this is same as the prior art, is not described in detail herein.
Embodiment seven
The blood perfusion device of the present embodiment comprises cylindrical shell and end cap equally, the both ends open of cylindrical shell and coordinating with end cap respectively, and this end cap is identical with the end cover structure of embodiment one, and the axial length in adsorbent containment chamber and the ratio of its maximum gauge are 2.7.As shown in Figure 20 and Figure 21, sealing circle 66 is made up of plane plain cushion 661 and bulge loop part 662 sealing ring 66 between end cap and barrel end, and this bulge loop part 662 is the circular arc of diameter 0.1-0.5mm.Other structures are also all identical with embodiment one, repeat no more herein.
Embodiment eight
The structure of the blood perfusion device of the present embodiment is substantially identical with embodiment one, difference is mainly, position in an interference fit between filter screen and filter screen installation position, the axial length in adsorbent containment chamber and the ratio of its maximum gauge are 4.0, and the tapering of the lid 133 of end cap 13 is 35 °.
Embodiment nine
The structure of the blood perfusion device of the present embodiment is substantially identical with embodiment one, and difference is mainly, the mode with threaded engagement between filter screen and filter screen installation position positions, the axial length in adsorbent containment chamber and the ratio 3.5 of its maximum gauge.
Above-described is only the preferred embodiment of the present invention, it should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement and not exceed protection scope of the present invention.
Claims (11)
1. apparatus for purifying blood, comprise cylindrical shell and the filter screen being positioned at this cylindrical shell both end sides, described have adsorbent containment chamber between the filter screen of both end sides, it is characterized in that: the axial length in described adsorbent containment chamber and the ratio of its maximum gauge are 2.5-4.0.
2. apparatus for purifying blood according to claim 1, it is characterized in that: described cylindrical shell tapered and have blood flow into end and blood outflow end, described blood outflow end is the opening end that diameter is larger, the diameter that described blood flows into end is less, this blood flows into end and comprises guide portion, limiting platform and blood mouth, wherein said guide portion is horn-like, and the tapering of this horn-like guide portion is 25-45 °; Described limiting platform is between described guide portion and described blood mouth, and this limiting platform is connected with the less one end of the diameter of this horn-like guide portion.
3. apparatus for purifying blood according to claim 1, it is characterized in that: also comprise flowing into described blood and hold and/or end cap that blood outflow end is connected, described end cap comprises the lid, blood mouth and the limiting platform between described lid and blood mouth that are connected, described lid is horn-like, described blood mouth is near the less one end of the diameter of this horn-like lid, and the tapering of described horn-like lid is 25-45 °.
4. apparatus for purifying blood according to claim 3, it is characterized in that: between the respective end of described end cap and described cylindrical shell, be provided with filter screen, described filter screen comprises rack and mesh sheet, described rack is roughly in hollow round table shape, it comprises the supporting walls as round platform end face and the guiding wall as frustum cone side, one end that described supporting walls is less with described guiding wall diameter is connected, and described mesh sheet is fixed on described supporting walls; The tapering of the guiding wall of described rack is substantially identical with the tapering of described horn-like lid.
5. apparatus for purifying blood according to claim 4, is characterized in that: described rack also comprises the circular mounting flange that one end larger with described guiding wall diameter is connected, and this mounting flange extends along the radial direction of described rack; Described filter screen is positioned between the respective end of described end cap and described cylindrical shell by this mounting flange, the supporting walls of described rack and closely cooperating near its blood mouth one end of described end cap, guiding wall and the described horn-like lid of described rack fit tightly, the axis of described mesh sheet and the dead in line of described blood mouth.
6. the apparatus for purifying blood according to Claims 2 or 3, is characterized in that: the inside of described limiting platform has the filter screen installation position being formed as cylindrical cavity, and be provided with filter screen in the middle of this filter screen installation position, described filter screen comprises rack and mesh sheet.
7. apparatus for purifying blood according to claim 6, is characterized in that: the diameter of effective filtration zone of described mesh sheet is 6mm-20mm.
8. apparatus for purifying blood according to claim 6, it is characterized in that: the two ends of this apparatus for purifying blood are equipped with described filter screen and corresponding filter screen installation position, connected by support bar between two groups of filter screens, the internal chamber wall of described filter screen installation position and the outer wall of described rack are shiny surface, described outer wall and described internal chamber wall fit tightly, the axial inner ends face of described rack is provided with support slot, the end of described support bar coordinates with described support slot grafting, thus makes described filter screen be fixed on described filter screen installation position.
9. apparatus for purifying blood according to claim 6, is characterized in that: the internal chamber wall of described filter screen installation position is provided with the buckle or female thread that are suitable for coordinating with described filter screen, and the rack of described filter screen is provided with corresponding locating slot or external screw thread.
10. apparatus for purifying blood according to claim 1, it is characterized in that: described blood flow into end and/or blood outflow end be provided with can with the external screw thread of the screw-internal thread fit on nut or end cap, described externally threaded end is provided with for preventing the notch opened, and described notch can match with the Unclosing structure that prevents on described nut or end cap.
11. apparatus for purifying blood according to claim 1, is characterized in that: described cylindrical shell is provided with adsorbent loading prompting mark.
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| CN201510561208.5A CN105107044A (en) | 2015-09-02 | 2015-09-02 | Blood purifier |
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| CN201510561208.5A CN105107044A (en) | 2015-09-02 | 2015-09-02 | Blood purifier |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106730995A (en) * | 2016-12-14 | 2017-05-31 | 天长市康宁甘油科技有限公司 | A kind of glycerine continuous stripping purifier |
| CN109069792A (en) * | 2016-04-05 | 2018-12-21 | 泰尔茂株式会社 | The manufacturing method of percutaneous catheter and percutaneous catheter pipe |
| CN109621163A (en) * | 2019-01-22 | 2019-04-16 | 胡金鼎 | A kind of Urology Surgery clinical catheter assembly apparatus |
| WO2020155618A1 (en) * | 2019-01-29 | 2020-08-06 | 广州康盛生物科技股份有限公司 | Encapsulation structure of blood plasma adsorber and adsorbent thereof |
| CN113289106A (en) * | 2021-06-30 | 2021-08-24 | 端源医疗科技无锡有限公司 | Blood coagulation and filtration device for hemodialysis, venous tube and hemodialysis device |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2170106Y (en) * | 1993-03-03 | 1994-06-29 | 天津市生物医学工程开发研究中心 | Adsorption pot for purifying blood |
| CN1278449A (en) * | 2000-07-28 | 2001-01-03 | 四川科力仪器技术有限公司 | Hollow fiber film blood purifier |
| CN2701447Y (en) * | 2004-04-17 | 2005-05-25 | 吴兆华 | Disposable blood perfusion device |
| CN201211354Y (en) * | 2008-05-21 | 2009-03-25 | 珠海丽珠医用生物材料有限公司 | Disposable blood perfusion device |
| CN201684226U (en) * | 2010-05-26 | 2010-12-29 | 重庆希尔康血液净化器材研发有限公司 | Hemoperfusion apparatus screen |
| JP5350286B2 (en) * | 2010-01-29 | 2013-11-27 | 日機装株式会社 | Blood purification column |
| CN204275132U (en) * | 2014-11-17 | 2015-04-22 | 珠海健帆生物科技股份有限公司 | A kind of apparatus for purifying blood that synchronously can realize dialysing and perfusion is treated |
| CN205145232U (en) * | 2015-09-02 | 2016-04-13 | 珠海健帆生物科技股份有限公司 | Blood purifying device |
-
2015
- 2015-09-02 CN CN201510561208.5A patent/CN105107044A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2170106Y (en) * | 1993-03-03 | 1994-06-29 | 天津市生物医学工程开发研究中心 | Adsorption pot for purifying blood |
| CN1278449A (en) * | 2000-07-28 | 2001-01-03 | 四川科力仪器技术有限公司 | Hollow fiber film blood purifier |
| CN2701447Y (en) * | 2004-04-17 | 2005-05-25 | 吴兆华 | Disposable blood perfusion device |
| CN201211354Y (en) * | 2008-05-21 | 2009-03-25 | 珠海丽珠医用生物材料有限公司 | Disposable blood perfusion device |
| JP5350286B2 (en) * | 2010-01-29 | 2013-11-27 | 日機装株式会社 | Blood purification column |
| CN201684226U (en) * | 2010-05-26 | 2010-12-29 | 重庆希尔康血液净化器材研发有限公司 | Hemoperfusion apparatus screen |
| CN204275132U (en) * | 2014-11-17 | 2015-04-22 | 珠海健帆生物科技股份有限公司 | A kind of apparatus for purifying blood that synchronously can realize dialysing and perfusion is treated |
| CN205145232U (en) * | 2015-09-02 | 2016-04-13 | 珠海健帆生物科技股份有限公司 | Blood purifying device |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109069792A (en) * | 2016-04-05 | 2018-12-21 | 泰尔茂株式会社 | The manufacturing method of percutaneous catheter and percutaneous catheter pipe |
| CN109069792B (en) * | 2016-04-05 | 2022-07-01 | 泰尔茂株式会社 | Percutaneous catheter and method for manufacturing percutaneous catheter tube |
| CN106730995A (en) * | 2016-12-14 | 2017-05-31 | 天长市康宁甘油科技有限公司 | A kind of glycerine continuous stripping purifier |
| CN109621163A (en) * | 2019-01-22 | 2019-04-16 | 胡金鼎 | A kind of Urology Surgery clinical catheter assembly apparatus |
| WO2020155618A1 (en) * | 2019-01-29 | 2020-08-06 | 广州康盛生物科技股份有限公司 | Encapsulation structure of blood plasma adsorber and adsorbent thereof |
| CN113289106A (en) * | 2021-06-30 | 2021-08-24 | 端源医疗科技无锡有限公司 | Blood coagulation and filtration device for hemodialysis, venous tube and hemodialysis device |
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