CN105106457A - Traditional Chinese medicine for treating erythrasma - Google Patents

Traditional Chinese medicine for treating erythrasma Download PDF

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Publication number
CN105106457A
CN105106457A CN201510564597.7A CN201510564597A CN105106457A CN 105106457 A CN105106457 A CN 105106457A CN 201510564597 A CN201510564597 A CN 201510564597A CN 105106457 A CN105106457 A CN 105106457A
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parts
erythrasma
chinese medicine
fructus
treatment
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粘芙蓉
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Abstract

The invention relates to a traditional Chinese medicine for treating erythrasma. The traditional Chinese medicine is prepared from the following medicinal raw materials in parts by weight: 10 parts of bitter orange fruit, 10 parts of menispermum dauricum, 15 aparts of diospyros cathayensis steward, 20 parts of fructus rosae laevigatae, 20 parts of fructus corni, 12 parts of ranunculaceae Clematis meyeniana var.granulata and 12 parts of luffa cylindrica. Clinical experiments prove that the traditional Chinese medicine can be used for effectively and safely treating erythrasma.

Description

A kind of Chinese medicine being used for the treatment of erythrasma
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of erythrasma.
Background technology
Erythrasma is caused by the corynebacterium minutissimum of corynebacterium, is apt to occur in skinfold position, and skin lesion major determinant is boundary clearly erythema.Confirm that this kind of corynebacterium is the pathogen of erythrasma with ultramicroscope.This Pseudomonas corynebacterium is a kind of diphtheroid, and Gram's staining is positive, often colonizes in the nose of normal person, pharynx, eye, external auditory meatus and skin surface, and when local warm moist or skin injury, this bacterium invades horny layer and causes infection.Typical lesions is the patch that boundary is clear, edge is irregular.Start to take on a red color, subsequently overstrike.New infringement is smooth, and older infringement is wrinkling or have a large amount of pityrosporum sample squama.Be common in pars inguinalis that thigh root contacts with scrotum, axillary fossa, buttocks stitch, the skin at gauffer position such as under breast, between the four or five toe.Generally do not have subjective symptoms, being subject to friction at pars inguinalis stimulates, and can cause pruritus and lichenification.Involve skin around the rectum, can pruritus ani be caused.Another erythrasma is more common in the patient of diabetes and other debilitating illnesses.Show as general property erythrasma, skin lesion is boundary clearly bronzing patch, is distributed widely in trunk and extremity.Diabetes may be the precipitating factors that this kind of erythrasma occurs.
Medical material present Research involved in the present invention is as follows:
FRUCTUS CITRI AURANTII AMARAE [another name] is justified from generation to generation, from generation to generation, Soviet Union Fructus Aurantii.[source] is the fruit of rutaceae CitrusaurantiumL.Var.amara Engl..Winning immature green fruit 7 ~ August, is two halves from middle part crosscut, dries or dries.[nature and flavor] cold nature, bitter in the mouth, acid.[return through] returns spleen, stomach warp.[function cures mainly] promoting the circulation of QI to alleviate the stagnation in middle-JIAO, helps digestion, reduces phlegm.For the vexed distending pain of breast abdomen, accumulation of food in the stomach and intes tine due to indigestion, phlegm retention, proctoptosis.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[attention] it is cool in nature, is easy to dynamic and vomits, cold syndrome of the stomach person work as and be cautious use of.[extracts] " China's book on Chinese herbal medicine ".
Asiatic moonseed [another name] Canis familiaris L. seedling of Fructus Vitis viniferae, little Ge perfume, sub of willow, Radix Stephaniae Tetrandrae rattan, Huang Youxiang, assorted sub-Seedling, little Sinomenium acutum, xanthorrhiza rattan, golden centipede, mountain region melon seedling, seedling sprout of climbing the mountain.[source] is the rattan of menispermaceous plants Caulis menispermi, gathers and stores: autumn taps, debranching leaf, and clean, cutting, dries.[nature and flavor] are bitter, cold.[return through] returns liver; Lung; Intestinal warp.[function cures mainly] heat-clearing and toxic substances removing; Reducing swelling and alleviating pain.Main lumbago; Scrofula; Laryngopharynx swelling and pain; Diarrhoea dysentery; Swelling and pain of hemorrhoid.[usage and dosage] takes orally: decoct soup, 9-15g.[extracts] " China's book on Chinese herbal medicine ".
Monkey door [another name] Rhizoma Curculiginis fruit.[source] is the fruit of Ebenaceae plant Foochow Fructus Kaki.Gather and store: 7-9 month fructescence is plucked, using fresh herb or dry.[nature and flavor] are bitter; Warm in nature.[return through] returns lung, the heart, kidney channel.[function cures mainly] Yishen Jianpi.Main kidney deficiency, spleen is weak; Lassitude and weak.Restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.[usage and dosage] takes orally: decoct soup, 3 ~ 12g.[extracts] " China's book on Chinese herbal medicine ".
Fructus Rosae Laevigatae [another name] Cortex Hemipteleae Davidii, sub, golden small-mouthed jar of Fructus Rosae Normalis, Catunaregam spinosa (Thunb.) Tirveng., Gallus jabouillei chieftain, sugared Oriolus chinensis diffusus, Chinese bush cherry ball, sugar bowl, confection, yellow bur, Mel tank, Semen Arecae, golden tall bottle with spout, balaustine, rattan hook, Mantidis fruit, sugared bur [source] this product are the dry mature fruit of rosaceous plant Fructus Rosae Laevigatae Rosa.Gather when 10 ~ November, fruit maturation reddened, dry, except deburring.[nature and flavor] are sour, sweet, puckery, flat.[return through] returns kidney, bladder, large intestine channel.[function cures mainly] reinforcing the kidney and controlling nocturnal emission, reducing urination and antidiarrheal.Control spermatorrhea, the enuresis, frequent micturition, insufficiency of the spleen dysentery, the deficiency of the lung is breathed with cough, spontaneous sweating, bleeding not during menses.[usage and dosage] takes orally: decoct soup, 6 ~ 12g.[attention] has loose bowels because burning hot spouting diarrhea person should not use; Incontinence of urine and vital essence slippage, because of the person of obtaining in deficiency of YIN heated, should not be used.[extracts] " China's book on Chinese herbal medicine ".
Mountain Lay English [another name] another name for Sichuan Province Fructus Jujubae, Mus is vowed, chicken foot, Fructus Corni, real Fructus Jujubae, meat Fructus Jujubae, Fructus Corni, Fructus Corni, medicine Fructus Jujubae.[source] this product is the drying and ripening sarcocarp of Lai Yingke plant mountain, mountain Lay English.Picking fruit when time of the year when autumn changes into winter, peel reddened, after drying with slow fire or putting in boiling water and slightly scald, in time except removal core, dry.[nature and flavor] are sour, puckery, tepor.[return through] returns liver, kidney channel.[function cures mainly] liver and kidney tonifying, essence astringing and desertion stemming.For vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating is collapsed.Interior-heat is quenched one's thirst.[usage and dosage] takes orally: decoct soup, 6 ~ 12g.[attention] all gate of vitality's heateds, strong sun not flaccidity, have damp and hot, and the puckery person of urine leaching avoids clothes.[extracts] " China's book on Chinese herbal medicine ".
Husky leaf Radix clematidis floridae [another name] cartilage Cortex Ampelopsis Aconitifoliae Radicis, threeleaf akebia, Tacca chantrieri Andre.[source] is ranunculaceae plant husky leaf Radix clematidis floridae Herb.Gather and store: summer, autumn adopt, clean, cutting, dries.[nature and flavor] bitter in the mouth; Pungent; Cold in nature.[return through] enters lung, liver, kidney channel.[function cures mainly] clearing away heat and promoting diuresis; Dredge the meridian passage.Main edema; Dysuria; Rheumatic arthralgia; Galactostasis; Carbuncle sore furuncle and phyma.[usage and dosage] takes orally: decoct soup, 15 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Hypericum perforatum L. [another name] little Herba Cynanchi Hancockiani, little grass of passing by one's way, Herba hyperici attenuati.[source] is Hypericaceae hypericum Herba Hyperici perforati, with all herbal medicine.To gather for 7 ~ October herb, clean, dry.[nature and flavor] are bitter, pungent, flat.[function cures mainly] heat-clearing and toxic substances removing, regulating menstruation, hemostasis.For spitting blood, spitting of blood, menoxenia; Wound hemorrhage is controlled in external, carbuncle furuncle and phyma poison, burn and scald.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of erythrasma, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing erythrasma.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of erythrasma, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: FRUCTUS CITRI AURANTII AMARAE 10 parts, asiatic moonseed 10 parts, monkey door 15 parts, Fructus Rosae Laevigatae 20 parts, mountain Lay English 20 parts, husky leaf Radix clematidis floridae 12 parts, Hypericum perforatum L. 12 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and erythrasma patient 100 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 50 example and matched group 50 example at random, treatment group man 28 example, female 22 example, 16 ~ 49 years old age; Matched group man 23 example, female 27 example, 17 ~ 46 years old age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national erythrasma clinical speciality:
(1) typical lesions is the patch that boundary is clear, edge is irregular.Start to take on a red color, subsequently overstrike.New infringement is smooth, and older infringement is wrinkling or have a large amount of pityrosporum sample squama.
(2) be common in pars inguinalis that thigh root contacts with scrotum, axillary fossa, buttocks stitch, the skin at gauffer position such as under breast, between the four or five toe.
(3) coral fluoroscopy under the skin Wood light of cutaneous lesion.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.2 weeks courses for the treatment of.
The oral erythromycin of matched group, each 0.25g, every day 4 times, 2 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Clinical cure: skin lesion disappears completely, inflammation disappears;
Effective: skin lesion disappears >=and 70%, inflammation obviously alleviates;
Effective: skin lesion disappears 30% ~ 69%, and inflammation alleviates;
Invalid: skin lesion disappears <30%.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Group n Clinic control Effective Effectively Invalid Total effective rate (%) Serious adverse reaction example
Treatment group 50 28 13 8 1 98% 0
Matched group 50 16 11 14 9 82% 0
Visible, the medicine that the present invention obtains can safe and effective treatment erythrasma, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: FRUCTUS CITRI AURANTII AMARAE 10 grams, asiatic moonseed 10 grams, monkey door 15 grams, Fructus Rosae Laevigatae 20 grams, mountain Lay English 20 grams, husky leaf Radix clematidis floridae 12 grams, Hypericum perforatum L. 12 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of erythrasma.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: FRUCTUS CITRI AURANTII AMARAE 10 grams, asiatic moonseed 10 grams, monkey door 15 grams, Fructus Rosae Laevigatae 20 grams, mountain Lay English 20 grams, husky leaf Radix clematidis floridae 12 grams, Hypericum perforatum L. 12 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of erythrasma.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: FRUCTUS CITRI AURANTII AMARAE 10 grams, asiatic moonseed 10 grams, monkey door 15 grams, Fructus Rosae Laevigatae 20 grams, mountain Lay English 20 grams, husky leaf Radix clematidis floridae 12 grams, Hypericum perforatum L. 12 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of erythrasma.Oral, every bu Morning Afternoon Evening is taken for three times.

Claims (4)

1. one kind is used for the treatment of the Chinese medicine of erythrasma, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: FRUCTUS CITRI AURANTII AMARAE 10 parts, asiatic moonseed 10 parts, monkey door 15 parts, Fructus Rosae Laevigatae 20 parts, mountain Lay English 20 parts, husky leaf Radix clematidis floridae 12 parts, Hypericum perforatum L. 12 parts.
2. be used for the treatment of the Chinese medicine of erythrasma as claimed in claim 1, it is characterized in that, its preparation method is: take: FRUCTUS CITRI AURANTII AMARAE 10 parts, asiatic moonseed 10 parts, monkey door 15 parts, Fructus Rosae Laevigatae 20 parts, mountain Lay English 20 parts, husky leaf Radix clematidis floridae 12 parts, Hypericum perforatum L. 12 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of the Chinese medicine of erythrasma as claimed in claim 1, it is characterized in that, its preparation method is: take: FRUCTUS CITRI AURANTII AMARAE 10 parts, asiatic moonseed 10 parts, monkey door 15 parts, Fructus Rosae Laevigatae 20 parts, mountain Lay English 20 parts, husky leaf Radix clematidis floridae 12 parts, Hypericum perforatum L. 12 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of the Chinese medicine of erythrasma as claimed in claim 1, it is characterized in that, its preparation method is: take: FRUCTUS CITRI AURANTII AMARAE 10 parts, asiatic moonseed 10 parts, monkey door 15 parts, Fructus Rosae Laevigatae 20 parts, mountain Lay English 20 parts, husky leaf Radix clematidis floridae 12 parts, Hypericum perforatum L. 12 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
CN201510564597.7A 2015-09-08 2015-09-08 Traditional Chinese medicine for treating erythrasma Withdrawn CN105106457A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1736455A (en) * 2004-12-13 2006-02-22 刘文奇 Traditional Chinese medicine composition for treating tinea
CN104056103A (en) * 2014-06-24 2014-09-24 俞天阳 Traditional Chinese medicine for treating woman chloasma
CN104721368A (en) * 2015-04-04 2015-06-24 淄博夸克医药技术有限公司 Traditional Chinese medicine for treating eczema

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1736455A (en) * 2004-12-13 2006-02-22 刘文奇 Traditional Chinese medicine composition for treating tinea
CN104056103A (en) * 2014-06-24 2014-09-24 俞天阳 Traditional Chinese medicine for treating woman chloasma
CN104721368A (en) * 2015-04-04 2015-06-24 淄博夸克医药技术有限公司 Traditional Chinese medicine for treating eczema

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Application publication date: 20151202