CN105105815A - Medical ligating clip - Google Patents
Medical ligating clip Download PDFInfo
- Publication number
- CN105105815A CN105105815A CN201510643133.5A CN201510643133A CN105105815A CN 105105815 A CN105105815 A CN 105105815A CN 201510643133 A CN201510643133 A CN 201510643133A CN 105105815 A CN105105815 A CN 105105815A
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- Prior art keywords
- jig arm
- ligation clip
- groove
- center line
- medical ligation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/122—Clamps or clips, e.g. for the umbilical cord
- A61B17/1227—Spring clips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/0084—Material properties low friction
- A61B2017/00849—Material properties low friction with respect to tissue, e.g. hollow organs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
- A61B2017/00871—Material properties shape memory effect polymeric
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B2017/12004—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord for haemostasis, for prevention of bleeding
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Reproductive Health (AREA)
- Chemical & Material Sciences (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Surgical Instruments (AREA)
Abstract
The invention relates to a medical ligating clip which is used for surgical operation. The medical ligating clip is structurally characterized in that the medical ligating clip comprises a first clamping arm (1) and a second clamping arm (2) which are of arc structures, the outer surfaces of the clamping arms are in the shapes of circular surfaces (3), concave-convex grooves (4) are formed in the midcourt lines of the inner surfaces of the two clamping arms, the two clamping arms are connected through an elastic hinge (5), the two ends of the medical ligating clip are provided with lock catch structures (6) matched with each other, and meanwhile the two sides of the midcourt lines of the inner surfaces of the two clamping arms are provided with protruding strips (7), wherein a 20-45-degree included angle is formed between each protruding strip and the corresponding clamping arm. The medical ligating clip is formed by conducting molten plastic injection on monomer homopolymer or copolymer of one or more of high-molecular polymer polyformaldehyde, polyetherimide, polyether sulfone and polyethylene glycol terephthalate which are better in biocompatibility.
Description
Technical field
The present invention relates to a kind of medical device product, particularly a kind of Medical ligation clip of preparing of a kind of bioabsorbable polymer material, is mainly used in ligation and the hemostasis of surgery Minimally Invasive Surgery medium vessels or biliary tract tissue.
Background technology
For fully to expose surgical field of view in surgical procedures, need to carry out ligation to the fracture blood vessel in otch, hemorrhage to stop.Hemostatic technique has become one of core of basic operative techniques technology, and the surgical procedures at any position of human body almost relates to hemorrhage with hemostasis bar none.Be generally carry out ligation with stitching thread again after clamping fracture blood vessel with mosquito forceps, this method operation is cumbersome, reduces procedure efficiency; Another kind method carrys out blocking blood flow by ligation clip, mainly metal and macromolecular material, the aneurysm clamp such as used in aneurysm surgery, the gall duct clamp etc. in biliary surgery, and commercialized product mainly contains silver brain clip, titanium folder, Hem-o-Lok folder etc. at present.
Vascular ligation operation common method in clinical operation has suture knotting, titanium folder is closed, macromolecule nonabsorable ligation clip is closed.Wherein suture ligation carries out vessel sealing, complicated operation, with duration, higher to patient's operating technology level requirement; The closed blood vessel of titanium folder, need close with the use of to the blood vessel of ligation required in operation with special titanium clamp pincers, swift and convenient to operate, requires lower to patient's operant level.But after metal clip Permanent implantation human body, due to some defects of metal clip itself, can produce in body free, have electric conductivity, medical imaging such as B ultrasonic or nuclear-magnetism etc. produce artifact bad phenomenon.
In recent years, the medical apparatus and instruments of closed blood vessel and biliary tract tissue in clinical, mainly macromolecular material hemostatic clamp, its fundamental characteristics is nontoxic non-stimulated, good biocompatibility, and safety clamp closes, can keep stable chemical property in vivo, acid-alkali-corrosive-resisting is strong, and askiatic is disturbed.But in use still there are some problems, mainly show the stability that folder closes and fastness not, there will be slippage; In clip long-term existence body, because structural corner angle have long-term wearing and tearing to tissue, therefore be necessary that carrying out design to the product structure of ligation clip improves.Ligation clip after the present invention improves overcomes above-mentioned shortcoming, can better meet clinical demand.
Summary of the invention
For overcoming the technical deficiency of existing product, the present invention is by Material selec-tion, and innovative design is carried out in preparation technology and product structure design aspect, provides a kind of safe and reliable, slip-off preventing, the Medical ligation clip of good biocompatibility.
For this reason, the invention provides a kind of Medical ligation clip prepared by a kind of bioabsorbable polymer material.
It is constructed as follows: first jig arm (1) of arcuate structure and the second jig arm (2), jig arm cross section semicircular in shape, square or trapezoidal shape (3), article two, the inner surface midline position of jig arm is tongue and groove (4), article two, between jig arm, adopt elasticity hinge (5) to connect, two ends are the buckle structure (6) cooperatively interacted, simultaneously the design of the inner surface center line both sides of two jig arm and jig arm be 20 ?the raised line (7) of miter angle.
Wherein, described Medical ligation clip adopts the elastic polymer material of non-degradable to make, and two jig arm are by inner surface to the rounded design of outer surface, and jig arm outer surface is without corner angle, and snap close (6) is concaveconvex structure or grab and notch.
Wherein, the elastic polymer material of described non-degradable comprise any one in polyformaldehyde, Polyetherimide, polyether sulfone, polyethylene terephthalate homopolymer or in them any two kinds or two or more monomer copolymers through melting injection mo(u)lding.
Wherein, the inner surface center line of two described jig arm designs in tongue and groove (4) respectively, design respectively with jig arm center line in the inner surface center line both sides of two jig arm be 20 ?the raised line (7) of miter angle.
Wherein, adopt elasticity hinge (5) link in the middle of two described jig arm, elasticity hinge (5) is long crescent shape.
Wherein, the concavo-convex buckle structure that the free end snap close (6) of described jig arm is grab and draw-in groove.
Wherein, the elastic polymer material of described non-degradable is carried out melting injection moulding with following condition and is prepared from, mold preheating temperature 80-150 DEG C, fusion temperature is homopolymer material is 190-300 DEG C, copolymer material is 190-350 DEG C, injection pressure be 40 ?130MPa, the dwell time is 5-30s, adopt TOP-TIP.
Wherein, the inner surface center line of two described jig arm is respectively tongue and groove (4), and namely the center line of the first jig arm is raised line, and the center line of the second jig arm is groove, and wherein the height of raised line or the degree of depth of groove are at more than 0.05mm; Designing respectively with jig arm center line on the inner surface center line both sides of two jig arm is the raised line (7) of 20 ?, 45 degree of angles, and the raised line (7) of the first jig arm and the second jig arm is in over-over mode.
Wherein, the intermediate connections of two described jig arm adopts long crescent shape structure, major diameter 0.1 ?1mm.
Wherein, the grab of the free end snap close of described jig arm and notch are the first jig arm free end is respectively grab groove, second jig arm free end is raised line, the groove of grab and free end distance be 1 ?2mm, the degree of depth of groove is more than 0.01mm, and the inner surface draw-in groove of raised line and the second jig arm is vertical configuration.
Medical ligation clip of the present invention adopts the elastic polymer material of non-degradable to make, mainly comprise any one in polyformaldehyde, Polyetherimide, polyether sulfone, polyethylene terephthalate or two or more monomer homopolymer or copolymer composition, be preferably polyacetal copolymer or homopolymer, be more preferably polyacetal copolymer material.
Two described arc jig arm are disc design by inner surface to outer surface, and namely the outer surface of jig arm is without corner angle, impulse-free robustness, reduces and the frictional force organizing Contact, the cross section semicircular in shape of two jig arm, height 2 ?between 5mm, be preferably 3 ?4mm.
In the present invention, the inner surface center line of two described jig arm designs respectively in concaveconvex structure, and being preferably wherein the first jig arm inner surface center line is raised line, and the second jig arm inner surface center line is corresponding groove, the degree of depth of raised line height and groove 0.5 ?1.5mm, be preferably 1mm.
Be more preferably that to design respectively with jig arm center line in the inner surface center line both sides of two jig arm be the raised line broached-tooth design of 20 ?miter angles, wherein convex surface sawtooth is over-over mode, and when ligation clip is closed, two-arm is mutually interted and coordinated, and strengthens folder and closes effect, anti-slip.Be preferably raised line and become miter angle with inner surface center line, the height of raised line is 0.05mm, length 0.8mm.
In the present invention, the link of elasticity hinge is adopted in the middle of two described jig arm, for a kind of articulated manner of flexibility, the first jig arm and the second jig arm not only can be made to rotate, and when turning to assigned address, the slip of certain distance can be carried out between two jig arm, described jig arm free end grab and notch can be made like this to lock easily and open.Its Elastic hinge is long crescent shape, and preferred major diameter, between 0.1 ?1mm, is more preferably 0.5mm, and when ligation clip closes, elasticity hinge place is seamless, avoids harbor bacteria or other microorganisms, causes infecting.
In the present invention, the grab of the free end snap close of described jig arm and notch are the first jig arm free end is respectively grab groove, second jig arm free end is raised line, the groove of grab and free end distance be 1 ?2mm, the degree of depth of groove is more than 0.01mm, and the inner surface draw-in groove of raised line and the second jig arm is vertical configuration, when clip closes, the groove of grab free end and the raised line of draw-in groove free end coincide mutually, strengthen the closed stability of snap close.
Ligation clip in the present invention, the secure latch that the free end of two jig arm is mutually locked is negative and positive fastening structure, when coordinating applicator to use, after folder closes, two snap closes mutually fasten and produce enough locker power, make to be pressed from both sides to close blood vessel or pipeline tissue can firmly close, and are less likely to occur to come off.
The ligation clip structural design related in foregoing invention, be mainly used in ligation and folder in product use procedure and close the guarantee of effect, as product structure design basis, the elastic polymer material of the non-degradable described in employing is carried out melting Shooting Technique with following condition and is prepared from, mold preheating temperature 80-150 DEG C, fusion temperature is 190-350 DEG C, and injection pressure is 40-130MPa, dwell time is 5-30s, adopts TOP-TIP.We take POM-H Acetal homopolymer as moulding material in the following embodiments, specifically describe product molding proces s parameters.
Medical ligation clip of the present invention, article two, jig arm is trapezoidal design by inner surface to outer surface, the mechanical property basis ensureing jig arm increases the contact area of jig arm and tubular tissue, the inner surface center line of two jig arm is designed to the concaveconvex structure of cooperation respectively simultaneously, article two, the middle of jig arm adopts the link of elasticity hinge, free end is the buckle structure cooperatively interacted, strengthen snap close and stability, design respectively with jig arm on the inner surface center line both sides of two jig arm is the raised line at 20-45 degree angle simultaneously, strengthen Junctional tissue power when ligation clip closes, prevent ligation clip slippage.Medical ligation clip good biocompatibility of the present invention, reasonable in design, folder closes effective, and anticreep is reasonable in design, and operation technique is convenient, can meet different clinical demands.
Compared to the prior art, structure is improved in the present invention, and fabrication process parameters adjusts, and is conducive to Clinical practice, further illustrates beneficial effect of the present invention below by way of experimental data:
| Structure | Folder closes effect | Anticreep effect | Biocompatibility | |
| The present invention | More reasonable | Better | Better | 100％ |
| Prior art | Unreasonable | Difference | Difference | 98％ |
Accompanying drawing illustrates:
Fig. 1 Total Product structural representation
The outer surface of Fig. 2 jig arm is in circle planar structure
The elasticity hinge of Fig. 3 two arc jig arm junctions is long crescent structure
The inner surface structure schematic diagram of Fig. 4 two jig arm
The grab of the free end snap close of Fig. 5 jig arm and notch
Detailed description of the invention
Be described further the specific embodiment of the present invention below in conjunction with accompanying drawing, content of the present invention is not limit
In embodiment, other constructional variant can be had, and do not depart from the scope of the present invention.
Embodiment 1
There is provided a kind of Medical ligation clip and preparation method thereof to achieve the object of the present invention, the elastomeric polymer composition that this ligation clip adopts hardness higher, polyacetal copolymer material is adopted in the present embodiment, be injected in the mould cavity of given shape through melting, key process parameter is set to: mold preheating temperature 120 DEG C, fusion temperature is 210 DEG C, injection pressure is 100MPa, dwell time is 20s, adopt TOP-TIP, but concrete material character and product forming technique influence factor need to take into full account, be embodied in shown in following table, obtain the ligation clip of molding.The Medical ligation clip of molding is packed, can in clinical practice after ethane via epoxyethane sterilization treatment.
Table one polyformaldehyde elastomer is to the analysis of Influential Factors of Shooting Technique
The mechanical property of embodiment 2 Medical ligation clip
In a preferred detailed description of the invention of the present invention, Medical ligation clip has good mechanical property:
1) gripping performance: after ligation clip clamps the medical sutures silk thread of a 3-0 specification, arrests any one end of silk thread, and be nature suspension status by silk thread, the ligation clip that silk thread holds is without any sliding phenomenon.
2) tensile property: after ligation clip folder closes, pulling open product with strain gauge with the speed of 50mm/min, the snap close of clip can not be thrown off under the tension force of 25N.
3) fatigue performance: ligation clip closes φ 6mm at folder, wall thickness 0.8mm, hardness, at the silica gel tube of shore 55-65 degree, bears 50kPa overpressure after 48 hours, and the snap close of ligation clip is without phenomenons such as disengagement or fractures.
The structural design of embodiment 3 Medical ligation clip
In a preferred detailed description of the invention of the present invention, two arc jig arm of Medical ligation clip design (as Figure of description 2 and 4) by inner surface to the disc shape structural design of outer surface and the concaveconvex structure of two jig arm center lines, effectively enhance closure strength and the stability of clip, avoid in the long-time body of ligation clip, to friction and the damage of body tissue simultaneously.
Claims (10)
1. a Medical ligation clip, it is characterized in that, it is constructed as follows: first jig arm (1) of arcuate structure and the second jig arm (2), jig arm cross section semicircular in shape, square or trapezoidal shape (3), article two, the inner surface midline position of jig arm is tongue and groove (4), article two, between jig arm, adopt elasticity hinge (5) to connect, two ends are the buckle structure (6) cooperatively interacted, simultaneously the design of the inner surface center line both sides of two jig arm and jig arm be 20 ?the raised line (7) of miter angle.
2. Medical ligation clip according to claim 1, it is characterized in that: described Medical ligation clip adopts the elastic polymer material of non-degradable to make, article two, jig arm by inner surface to the rounded design of outer surface, jig arm outer surface without corner angle, the grab that snap close (6) is concaveconvex structure and notch.
3. Medical ligation clip according to claim 1, it is characterized in that, the elastic polymer material of described non-degradable comprises any one in polyformaldehyde, Polyetherimide, polyether sulfone, polyethylene terephthalate or two or more monomer homopolymer or copolymer through melting injection mo(u)lding.
4. Medical ligation clip according to claim 1, it is characterized in that, the inner surface center line of two described jig arm designs in tongue and groove (4) respectively, design respectively with jig arm center line in the inner surface center line both sides of two jig arm be 20 ?the raised line (7) of miter angle.
5. Medical ligation clip according to claim 1, is characterized in that, adopt elasticity hinge (5) link in the middle of two described jig arm, elasticity hinge (5) is long crescent shape.
6. Medical ligation clip according to claim 1, is characterized in that, the concavo-convex buckle structure that the free end snap close (6) of described jig arm is grab and draw-in groove.
7. Medical ligation clip according to claim 1, it is characterized in that, the elastic polymer material of described non-degradable is carried out melting injection moulding with following condition and is prepared from, mold preheating temperature 80-150 DEG C, fusion temperature is homopolymer material is 190-300 DEG C, and copolymer material is 190-350 DEG C, injection pressure be 40 ?130MPa, dwell time is 5-30s, adopts TOP-TIP.
8. Medical ligation clip according to claim 1, it is characterized in that, the inner surface center line of two described jig arm is respectively tongue and groove (4), and namely the center line of the first jig arm is raised line, the center line of the second jig arm is groove, and wherein the height of raised line or the degree of depth of groove are at more than 0.05mm; Designing respectively with jig arm center line on the inner surface center line both sides of two jig arm is the raised line (7) of 20 ?, 45 degree of angles, and the raised line (7) of the first jig arm and the second jig arm is in over-over mode.
9. Medical ligation clip according to claim 1, is characterized in that, the intermediate connections of two described jig arm adopts long crescent shape structure, major diameter 0.1 ?1mm.
10. Medical ligation clip according to claim 1, it is characterized in that, the grab of the free end snap close of described jig arm and notch are the first jig arm free end is respectively grab groove, second jig arm free end is raised line, the groove of grab and free end distance be 1 ?2mm, the degree of depth of groove is more than 0.01mm, and the inner surface draw-in groove of raised line and the second jig arm is vertical configuration.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510643133.5A CN105105815B (en) | 2015-10-02 | 2015-10-02 | A kind of Medical ligation clip |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510643133.5A CN105105815B (en) | 2015-10-02 | 2015-10-02 | A kind of Medical ligation clip |
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| Publication Number | Publication Date |
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| CN105105815A true CN105105815A (en) | 2015-12-02 |
| CN105105815B CN105105815B (en) | 2017-07-07 |
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| CN201510643133.5A Active CN105105815B (en) | 2015-10-02 | 2015-10-02 | A kind of Medical ligation clip |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105534558A (en) * | 2016-02-04 | 2016-05-04 | 徐斌 | Vascular clamp |
| CN106075543A (en) * | 2016-06-24 | 2016-11-09 | 山东省药学科学院 | A kind of adsorbable hemostatic ligation clip and preparation method thereof |
| CN106264646A (en) * | 2016-08-29 | 2017-01-04 | 张大宏 | Strongly run-resistant hemostatic clamp |
| CN106510940A (en) * | 2016-12-01 | 2017-03-22 | 湖州市中心医院 | Muscle folding clamp |
| CN108236484A (en) * | 2016-12-27 | 2018-07-03 | 江苏风和医疗器材股份有限公司 | Hemostatic clamp |
| CN110811743A (en) * | 2018-08-13 | 2020-02-21 | 柯惠Lp公司 | Ligation clip with improved hinge part |
| CN111234289A (en) * | 2020-02-11 | 2020-06-05 | 南通大学 | Anti-adhesion polyformaldehyde ligation hemostatic clamp and preparation method and application thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050165423A1 (en) * | 2004-01-23 | 2005-07-28 | Pilling Weck Incorporated | Ligating clip with integral tissue-securing mechanism |
| CN101507646A (en) * | 2009-03-26 | 2009-08-19 | 杭州康基医疗器械有限公司 | Vascular clamp, closed tongs, vascular clamp die and production method of vascular clamp |
| CN201831920U (en) * | 2010-05-20 | 2011-05-18 | 仁齐企业有限公司 | Improved structure of artery clamp |
| CN203169257U (en) * | 2013-04-06 | 2013-09-04 | 许艳春 | Umbilical cord clamp |
| CN204562278U (en) * | 2015-03-16 | 2015-08-19 | 南京东万生物技术有限公司 | Tissue closure presss from both sides |
| CN205234564U (en) * | 2015-10-02 | 2016-05-18 | 北京光辉天成医疗科技有限公司 | Medical ligation clamp |
-
2015
- 2015-10-02 CN CN201510643133.5A patent/CN105105815B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050165423A1 (en) * | 2004-01-23 | 2005-07-28 | Pilling Weck Incorporated | Ligating clip with integral tissue-securing mechanism |
| CN101507646A (en) * | 2009-03-26 | 2009-08-19 | 杭州康基医疗器械有限公司 | Vascular clamp, closed tongs, vascular clamp die and production method of vascular clamp |
| CN201831920U (en) * | 2010-05-20 | 2011-05-18 | 仁齐企业有限公司 | Improved structure of artery clamp |
| CN203169257U (en) * | 2013-04-06 | 2013-09-04 | 许艳春 | Umbilical cord clamp |
| CN204562278U (en) * | 2015-03-16 | 2015-08-19 | 南京东万生物技术有限公司 | Tissue closure presss from both sides |
| CN205234564U (en) * | 2015-10-02 | 2016-05-18 | 北京光辉天成医疗科技有限公司 | Medical ligation clamp |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105534558A (en) * | 2016-02-04 | 2016-05-04 | 徐斌 | Vascular clamp |
| CN106075543A (en) * | 2016-06-24 | 2016-11-09 | 山东省药学科学院 | A kind of adsorbable hemostatic ligation clip and preparation method thereof |
| CN106075543B (en) * | 2016-06-24 | 2021-11-23 | 山东省药学科学院 | Absorbable hemostatic ligation clamp and preparation method thereof |
| CN106264646A (en) * | 2016-08-29 | 2017-01-04 | 张大宏 | Strongly run-resistant hemostatic clamp |
| CN106510940A (en) * | 2016-12-01 | 2017-03-22 | 湖州市中心医院 | Muscle folding clamp |
| CN108236484A (en) * | 2016-12-27 | 2018-07-03 | 江苏风和医疗器材股份有限公司 | Hemostatic clamp |
| CN110811743A (en) * | 2018-08-13 | 2020-02-21 | 柯惠Lp公司 | Ligation clip with improved hinge part |
| CN111234289A (en) * | 2020-02-11 | 2020-06-05 | 南通大学 | Anti-adhesion polyformaldehyde ligation hemostatic clamp and preparation method and application thereof |
| CN111234289B (en) * | 2020-02-11 | 2022-04-01 | 南通大学 | Anti-adhesion polyformaldehyde ligation hemostatic clamp and preparation method and application thereof |
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| Publication number | Publication date |
|---|---|
| CN105105815B (en) | 2017-07-07 |
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Address after: 102629 no.1f10, block a, building 1, 25 Yongxing Road, Daxing biomedical industrial base, Zhongguancun Science and Technology Park, Daxing District, Beijing Patentee after: Beijing Guanghui Tiancheng Biotechnology Co.,Ltd. Address before: 102629 no.1f10, block a, building 1, 25 Yongxing Road, Daxing biomedical industrial base, Zhongguancun Science and Technology Park, Daxing District, Beijing Patentee before: BEIJING GUANGHUI TIANCHENG MEDICAL TECHNOLOGY Co.,Ltd. |
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