CA1212881A - Non-metallic, bio-compatible hemostatic clip (two identical piece clip) - Google Patents

Non-metallic, bio-compatible hemostatic clip (two identical piece clip)

Info

Publication number
CA1212881A
CA1212881A CA000437496A CA437496A CA1212881A CA 1212881 A CA1212881 A CA 1212881A CA 000437496 A CA000437496 A CA 000437496A CA 437496 A CA437496 A CA 437496A CA 1212881 A CA1212881 A CA 1212881A
Authority
CA
Canada
Prior art keywords
piece
clip
vessel
pieces
disposed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000437496A
Other languages
French (fr)
Inventor
L. Bruce Cranstoun
Stephen J. Failla
Alfred L. Schneider, Jr.
John S. Pedlick
John R. Menges
Bela T. Vincze
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethicon Inc
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Application granted granted Critical
Publication of CA1212881A publication Critical patent/CA1212881A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/122Clamps or clips, e.g. for the umbilical cord

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)

Abstract

NON-METALLIC, BIO-COMPATIBLE HEMOSTATIC CLIP (TWO
IDENTICAL PIECE CLIP) Abstract A two-piece, hemostatic clip wherein the pieces are substantially identical. Each piece has a first member with a vessel clamping surface and a second piece perpendicularly disposed from the said first member. The pieces interlock to occlude a vessel placed between the vessel clamping surfaces.

Description

NON-METALLIC, BIO-COMPATIBLE ~IEMOSTATIC CLIP (TWO
IDENTICAL PIECE CLIP) The present invention relates to hemostatic clips and more ~particularly to hemostatic clips fabricated from bio-compatible, polymeric materials which may be absorbable or non-absorbable in body tissue.

Background of the Invention In many surgical procedures, it is often necessary to ligate a plurali~y of vessels within the surgical site.
The vessels may be severed downstream of the ligated portion. In some instances, the vessels may be ligated in spaced apart areas and the portion of the vessel between the ligations removed. The purpose of ligating vessels is to maintain the surgical site free from an excess of blood and reduce blood loss in the patient. Also, in certain surgical procedures where tumors and the like are to be removed, the tumor or organ may have to be separated rom certain vessels. Before separation, the vessels are ligated. Once a blood vessel is completley shut off, hemostasis, that is, the natural closing of the end of the vessel so as to stop blood flow, will occur in several days depending on the vessel. The body, in the meantime, will continue to allow blood flow around the ligated area through appropriate capillaries and secondary vessels, with the natural physiological functicn of the body enlarging the bypass vessels until adequate blood flow is obtained. Hence, when ligating the vessel, there should be positive stoppage of the blood flow in the main vessel.
Failure to provide complete stoppage may cause blood loss in the patient and may also disrupt the natural hemostasis and concurrent manufacture of new passages of blood flow in the patient.

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In the past, this closing of the vessel was usually accom plished using ligatures, i.e. 7 filaments or thread which the doctor tied around the vessel to be closed. This is a time-consuming process and one wherein positive closure of the vessel is not always accomplished. In recent years hemostatic clips have replaced ligatures in surgical proce-dures to close blood vessels and other fluid ducts. Very often these hemostatic clips are narrow U or V-shaped strips formed of tantalum or stainless steel which are capable of lo being deformed and possess sufficient strength to retain the deformation when clamped about a blood vessel. The closing forces are developed by the deformation of the me-tal.

Recently, various types of clips have been made from bio-compatible polymeric materials which are absorbable or non-absorbable in body -tissue~ Examples of such clips are disclosed in Canadian Patent ~o. 1,162 9 453, 1,157,335; and 1,162,454~ and Canadian patent application Ser. No. ~25,396.

In hemostatic clips, it is important to have a clip with a positive lock or a positive closure of the vessel. The clip should be easily handled by the nurse and surgeon during the procedure so that it will remain sterile when taken from its package by the nurse with a suitable instrument 7 handed to the surgeon, and placed appropriately in the patient~ Many clips are designed to take advantage of certain physical properties of materials such as resiliency or deformability.
When this is done, the materials which may be used to make the clips are limited. It is desirable to configure a clip in such a manner that a satisfactory clip may be produced from any of the various bio-compatible materials whether they be absorbable or non-absorbable in body tissue. Our new clip meets all of the above requirements in that it is simple to manufacture and can be made from any of the various absorbable or non-absorbable polymeric materials. Our new clip produces a positive lock or closure of the vessel to which it is applied and is readily manipulated by the nurse or surgeon during the procedure.

Summary of the Present Invention A sterile, two-piece hemostatic clip for occluding vessels. The pieces are substantially identical in configuration and each piece comprises a first member having a vessel clamping surface and a second member disposedsubstantially perpendicular from one end of said first member from said vessel clamping surface. The first member has disposed at its opposite end an opening adapted to accept the second member of the other piece. Each piece includes means for locking the second member of the opposite piece to the first member with the vessel clamping surfaces of the pieces facing each other. In certain embodiments of the hemostatic clips of the present invention, the locking means may be adjustable to allow the clip to be used for various size vessels. Also 7 in some embodiments of the hemostatic clips of the present invention, the locking means may include an interference fit between the second member of one piece and the opening in th~ first member of the opposite piece.

According to a broad aspect of the present invention there is provided a sterile, two-piece hemostatic clip for occluding vessels. The pieces are substantially identical in configuration and each comprises a first member having a vessel clamping surface and a second member disposed from one end of the first member and substantially perpendicular thereto and on the same - 3a -side as -the vessel clamping surface. The second member has its free end terminating in a sharp point capable of penetrating human tissue. The first member has disposed at its opposite end an opening adapted to accept the second member of the other piece and means for locking the second member of one piece to the first member of the other piece with the vessel clamping surface of the pieces facing each other. The means for locking provides an interference fit between said second member of one piece and the opening of the other piece.
Brief Description of the Drawin~Ls The presen-t invention will be more fully described to conjunction with the accompanying drawings wherein:
Figure 1 is an enlarged perspective view of one embodiment of the two-piece clip of the present inven-tion depicting the pieces in an open position:

~2,~B~

Figure 2 is an enlarged perspective view of the clip of Figure 1 disposed closing a blood vessel;

Figure 3 is an enlarged perspective view o~ another embodiment of the clip of the present invention with the pieces disposed from each o~her;

Figure 4 is an enlarged perspective view of another embodiment of the new clip of the present invention with the pieces disposed from each other;

Figure 5 is a side view showing an instrument for applying the clips of the present invention; and Figure 6 is an enlarged perspective view showing a clip of the present invention in the jaws of the instrument depicted in Figure 5.

Detailed Description of the ~rawings Referring to the drawings, in Figure 1 there is shown a clip 10 of the present invention. The clip comprises a first piece 11 having a first member 12 with a vessel clamping surface 13. Disposed from one end of this member is a second member 14O The first and second member are perpendicular to each other and the second member is disposed from the vessel clamping surface of the first member. Disposed at the opposite end of the first member is an opening 15 through the member. The clip includes a second piece 16 substantially identical to the first piece in that the second piece comprises a first member 17 and second member 18 perpendicular to each other with the first member having a vessel clamping surface 19 and the second member disposed from that surface. The first member of the second piece also includes an appropriate opening 20 disposed at the opposite end from which the second member is disposed.

~21~

Each of the second members includes a plurality of ears 21 or beveled extensions on one surface. As may be seen in Figure 2, the pieces are placed on opposite sides of the vessel 22 to be occluded with the vessel clamping surfaces facing each other. The second member of one piece is inserted into the opening in the first member of the other piece and the pieces urged together allowing the ears to lock the pieces together by engaging the opposite surface 23 from the vessel clamping surface of the first member of the other piece.

In Figure 3 there is shown another embodiment of the clip of the present invention. Again, the clip 25 comprises a first piece and a second piece which are substan~ially identical in configuration. Each piece has a first member 26 with a clamping surface 27 and disposed from one end of the first member perpendicular to the vessel clamping surface is a second member 28. The second member termi~
nates in an arrowhead shaped area 29. At the opposite end of each first membe-c is a widened area 30 in which there is an opening 31. In use, the vessel clamping surfaces are placed on opposite sides of the vessel to be occluded and the arrowhead shaped portion of the second member of each piece forced through the opening in the first member of the opposite piece to close the vessel between the vessel clamping surfaces. In this embodiment adjustabil-ity for use with vessels of varying size is attained through deflection of members 26.

In Figure 4 there is shown yet another embodiment of the hemostatic clip of the present invention. The hemostatic clip 35 comprises two pieces of substantially identical configurations. Each piece has a first member 36 with a vessel clamping surface 37. Disposed from one end of the vessel clamping surface and perpendicular thereto is a second member 38. Disposed at the opposite end of that first member and through the vessel clamping surface is an opening 39. The opening may have raised areas disposed on its inner surface to provide an interference fit between the opening and the second member of the opposite piece or the second member may include protrusions 40 on its surface to provide such an interference fit. In use, the vessel clamping surfaces of the first members are placed on opposite sides of the vessel ~l to be occluded and the - second member is inserted into the opening of the opposite piece to close the vessel between the vessel clamping surfaces. In any embodiments of the clips, the two pieces may be attached if desired by a suitable strip 42 or band connecting the pieces together at any of a number of various positions. Such a strip is shown in the embodiment in Figure 4.

Figure 5 illustrates a forceps type ligating clip applier 43 comprising two handle members 44 and 45 crossing at a hinge point 46 and maintained in a normally open position by a spring 47. One handle extends beyond the hinge forming a jaw member 48 while the extension of the other handle also forms a corresponding jaw member 49. As is more clearly shown in Figure 6, the jaw members 4~ and 49 are substantially mirror images and are provided with channels 50 and 51 extending rearwardly from the tip of the jaws to guide the clip. The two pieces 52 and 53 of the clips are held in these channels by frictional engagement between the sides of the channel and the sides of the pieces. Each channel includes an appropriately disposed opening 54 to allow the second member of the piece held in the opposite channel to pass through that opening when the clip is closed about a blood vessel. The jaws of the applier are moved or positioned over the vessel to be occluded and the jaws of the applier closed and the clip locked on to the vessel. The friction is insufficient to hold the locked pieces of the clip and ., when the jaws are reopened the cllp is left on the vessel and the applier readily removed.

The clips o the present invention may be constructed in various sizes according to their intended function.
Hemostatic clips are usually less than 6 millimeters in length and 1 1/2 millimeters in width and have a vessel clamping surface of about 3 millimeters in length. The dimension of the clip may be reduced by about 50% for certain applications in microsurgery. Larger clips for special hemostatic applications may be about double the size of a typical hemosta~ic clip The various sizes of the clip may be preferably matched with individual appliers having jaws tailored to the size of the clip for best performance.

As can be appreciated, the configuration of our improved ligating clips allows the clip to be made from virtually any material. Our new clips may be made from both resilient and non-resilient materials as well as deformable and non-deformable materials. The final clip made from any of these materials adequately closes a blood vessel for a sufficient period of time to provide hemostatis and provides a suitable hemostatic clip.
The clip of the present invention is most conveniently molded of biologically acceptable polymeric material which may be absorbable or non-absorbable in body tissue.
Preferred absorbable polymers and copolymers include those of glycolide, lactide, and (p)dioxanone. Preferred non-absorbable polymers include nylon, polyester, and polypropylene. All of these materials have been demonstrated to be biologically acceptable when used as sutures or other implantable medical devices.

88~

The clips of the present invention are sterilized by any of the known sterilization techniques generally depending on the material used to make the clip. Examples of suitable sterilization techniques which may be used with our clips are ethylene oxide sterilization, radiation sterilization, such as cobalt irradiation, electron beam, heat or steam sterilization, etc., and the like.

The clips of the present invention may be easily and economically manufactured by injection molding and other suitable molding techniques well known in the art. As may be appreciated, because of the identical configuration of the two-pieces of the clip, the molding is simple and only one mold shape is required.
Having now described the present invention and certain specific embodiments, it will be readily apparent to those skilled in the art that many variations and modifications may be made to the present invention without departing from the spirit and scope thereof.

Claims (4)

The embodiments of the invention in which an exclusive property or privilege is claimed are defined as follows:
1. A sterile, two piece hemostatic clip for occluding vessels, said pieces being substantially identical in configuration, each piece comprising a first member having a vessel clamping surface and a second member disposed from one end of said first member and substantially perpendicular thereto and on the same side as said vessel clamping surface, said second member having its free end terminating in a sharp point capable of penetrating human tissue, said first member having disposed at its opposite end an opening adapted to accept the second member of the other piece, and means for locking the second member of one piece to the first member of the other piece with the vessel clamping sur-faces of the pieces facing each other, said means for locking provides an interference fit between said second member of one piece and said opening of the other piece.
2. A sterile, two-piece hemostatic clip according to claim 1 including a member connecting the two pieces together.
3. A sterile, two-piece hemostatic clip according to claim 1 made from an absorbable polymeric material.
4. A sterile, two-piece hemostatic clip according to claim 1 wherein the absorbable polymeric material is a polymer or copolymer of lactide, glycolide or p-dioxanone.
CA000437496A 1982-09-27 1983-09-23 Non-metallic, bio-compatible hemostatic clip (two identical piece clip) Expired CA1212881A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42472282A 1982-09-27 1982-09-27
US424,722 1982-09-27

Publications (1)

Publication Number Publication Date
CA1212881A true CA1212881A (en) 1986-10-21

Family

ID=23683628

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000437496A Expired CA1212881A (en) 1982-09-27 1983-09-23 Non-metallic, bio-compatible hemostatic clip (two identical piece clip)

Country Status (4)

Country Link
JP (1) JPS5982844A (en)
CA (1) CA1212881A (en)
DE (1) DE3334801A1 (en)
GB (1) GB2128478B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108236482A (en) * 2016-12-27 2018-07-03 江苏风和医疗器材股份有限公司 Hemostatic clamp

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0178469A3 (en) * 1984-10-15 1988-06-15 American Cyanamid Company Nonmetallic surgical clip
US4686983A (en) * 1986-04-08 1987-08-18 Gerald Leisman Apparatus and method for ligating a body vessel
FR2598905B1 (en) * 1986-05-22 1993-08-13 Chevalier Jean Michel DEVICE FOR INTERRUPTING THE CIRCULATION OF A FLUID IN A FLEXIBLE WALL CONDUIT, IN PARTICULAR A HOLLOW VISCERE AND CLIP ASSEMBLY COMPRISING THIS DEVICE
DE3633974A1 (en) * 1986-10-06 1988-04-21 Bleier Waldemar LEAD CLIPS
US5575795A (en) * 1993-07-21 1996-11-19 Minneapolis Children's Medical Center Umbilical cord holder
US5575044A (en) * 1995-04-28 1996-11-19 Zornes; David A. High visibilty belt assembly
US7033378B2 (en) * 2002-09-20 2006-04-25 Id, Llc Surgical fastener, particularly for the endoluminal treatment of gastroesophageal reflux disease (GERD)
US6966919B2 (en) 2002-09-20 2005-11-22 Id, Llc Instrument for applying a surgical fastener particularly for the transoral treatment of gastroesophageal reflux disease (GERD)
US8454628B2 (en) 2002-09-20 2013-06-04 Syntheon, Llc Surgical fastener aligning instrument particularly for transoral treatment of gastroesophageal reflux disease
US7678122B2 (en) 2002-09-20 2010-03-16 Id, Llc Method of performing a treatment for gastroesophagheal reflux disease (GERD)
GB0302098D0 (en) 2003-01-29 2003-02-26 Univ London Improvements in and relating to surgical clips
CN104173090A (en) * 2014-09-11 2014-12-03 天津万和医疗器械有限公司 Continuous-shot absorbable clips and clip applier with same
CN104546059A (en) * 2014-12-31 2015-04-29 南通康盛医疗器械有限公司 Integrated anti-drag hemostatic and injection device for infusion
US20210030421A1 (en) * 2019-08-01 2021-02-04 Covidien Lp Two piece ligation clip

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3147754A (en) * 1961-04-17 1964-09-08 Walter R Koessler Device for controlling incontinence
GB972731A (en) * 1961-05-31 1964-10-14 Mihaly Gerendas Improvements in or relating to artery clamps
US3760811A (en) * 1970-01-20 1973-09-25 D Andrew Endotracheal tube clamp
US3916908A (en) * 1973-06-18 1975-11-04 Harry H Leveen Disposable bowel clamp and detachable applicator
IN151996B (en) * 1979-06-18 1983-09-17 Ethicon Inc

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108236482A (en) * 2016-12-27 2018-07-03 江苏风和医疗器材股份有限公司 Hemostatic clamp

Also Published As

Publication number Publication date
GB8325726D0 (en) 1983-10-26
JPH0451175B2 (en) 1992-08-18
DE3334801A1 (en) 1984-03-29
GB2128478B (en) 1985-12-24
GB2128478A (en) 1984-05-02
JPS5982844A (en) 1984-05-14

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