JPS5985654A - Non-metallic living body compatible hemostatic clip - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to hemostatic clips, and more particularly to hemostatic clips constructed from biocompatible polymeric materials that can be absorbable or non-absorbable in body tissue. It is.

In many surgical procedures, often characterized by ligating multiple blood vessels within the surgical site, the patent canal can be cut downstream of the ligated portion.

In some cases, the blood vessel can be ligated in two spaced apart areas and the portion of the blood vessel between the ligations removed. The purpose of ligating blood vessels is to keep the surgical site free of excessive blood and to reduce blood loss to the patient. Additionally, in certain surgical procedures to remove tumors or the like, the tumor or organ must be separated from some blood vessels. Ligate the blood vessels before separation. When a blood vessel is completely closed, cessation of blood flow, rJ, occurs within a few days, depending on the blood vessel, and natural closure of the blood vessel end that stops blood flow. In the meantime, the body relies on the body's natural physiological ability to dilate these lateral ducts until adequate blood flow is obtained through the appropriate capillaries and secondary ducts. Therefore, when ligating a blood vessel, a reliable cessation of blood flow in the main canal must be performed.When a complete cessation fails, the patient It is believed to cause a loss of blood and disrupt natural hemostasis and the concomitant creation of new channels for blood flow through the patient.

In addition, vascular rF] chains are usually attached to sutures, i.e.
This was done using filament I- or twine, which the doctor tied around the blood vessel to be closed. This is a time consuming operation and one in which reliable closure of the vessel is not always achieved. In recent years, I have been in d3 for surgical procedures,
Hemostatic clips have been used in place of ligatures to close blood vessels and other fluid conduits. These hemostatic clips are U- or V-shaped narrow strips of tantalum or stainless steel mesh that can be deformed and have sufficient strength to maintain that deformation when tightening the blood vessel. It is. More recently, clips have been developed from various biocompatible polymeric materials that are absorbable or non-absorbable in body tissues. Such a lip is a common assignee's patent application No. 2761318.1981.
No. 282165, filed June 22, 1981, filed July 31, 1981, and described in further detail in (ET'l-1532).

In the manufacture of polymeric clips, the clips are
It is desirable that the structure be such that it can be made from naturally absorbable or non-absorbable polymers. These clips must be able to be manufactured from materials that are elastic or inelastic, deformable or non-deformable, etc. The clip must be of such construction that it can be securely secured at its border when closed around the occluded tapetum vessel.

The clip should be relatively easy and inexpensive to construct IFJ. Furthermore, the clip must be relatively easy to manipulate by the nurse and surgeon during the surgical procedure. The clip must be easily removed from its packaging, placed into the instrument in use, and handled without losing sterility during the surgical procedure.

What the inventors have discovered is that 31! ! This is an improved ligation clip that can be The new clip of the present invention is configured to securely lock in place and occlude blood vessels placed between the vessel clamping surfaces of the clip. The novel clip of the present invention can be handled quickly and easily. This ensures that the lip can be picked up by the nurse and kept in the device without any risk of it falling out of the device. Again, the instrument can be passed to the surgeon with little risk of the clip falling out of the instrument, and the surgeon can then simply apply the clip around the vessel to be occluded, all of which require sterility of the clip. You can do it while preserving your sexuality.

The sterile hemostatic clip of the present invention for occluding blood vessels consists of a pair of spaced apart leg members. Each leg member has parallel and mutually opposing vessel clamping surfaces. One end of both leg members is r! l] Make sure that the vessel-clamping surface can be placed on either side of the vessel to be occluded. The other ends of the leg members have adjustable radiets and pawl means connected by equivalent means;
Thereby, by adjusting the spacing between the vessel-clamping surfaces (1), it is possible to occlude a vessel located between the two surfaces. In some embodiments of the clips of the present invention, the outer surfaces of the leg members also span a portion of the outer surfaces (parallel) to help propel the vessel-clamping surfaces toward each other. .

The invention will be explained in more detail in conjunction with the drawings.

Referring to the drawings, FIG. 1 shows the clip of the present invention in the open position. This clip has a pair of leg members 1
It consists of 1 and 12. These leg members each have blood vessel clamping surfaces 13 and 14 that are arranged in parallel and are opposite each other. One end of the leg member is open, -h, and a radiet mechanism is present at the other end, the radiator l-1m side includes a member 15 extending perpendicularly from one leg member, This member 15 has suitable teeth 16 or serrations disposed on both sides thereof. The opposing leg member is the first leg member! I! Complementary hole 1 for receiving the white extension
8. This hole receives the teeth of the extension of the first leg member and holds both leg members in a given position r.
+c+ Appropriate protrusion 19 for fixing to Ii
, Zunawa 1. ') It has a pawl-shaped protrusion.

In certain embodiments of the inventive clip, this lug or pawl may be clamped to the outer surface 20 of the leg member. As seen more clearly in FIG. 2, the blood vessel 22 to be occluded is placed between the face tube clamping surfaces 13 and 14, and the IfO tube is occluded by driving the leg members toward each other. When the leg members are pushed toward each other and both leg members are closed, the closed position r'':) Jie!・DI 411
fixes both legs. Although we have shown a pawl-type mechanism with Radietsu 1~, we have used a similar gear-type mechanism consisting of an interlocking device that allows movement in one direction but prevents movement in the other direction, that is, the movement of the lever. C is also good.

FIG. 3 shows a forceps-shaped ligation clip 19 consisting of two prongs 26 and 27 intersecting at a hinge point 28 and held in the normal open position by a spring 29! It shows the equipment for use. One handle extends beyond the hinge to form a jaw member 30, and the extension of the other handle also forms a corresponding jaw member 31. As shown more clearly in FIG. 4, the holes 30 and 31 are of the same type 811, and each has a groove 3 extending rearward from the tip of the hole.
2 and 33. These covers hold the leg members 34,35 of the clip in place by frictional engagement with their sides.

The clip is first placed into the application in its open position. The jaws of the instrument are moved or positioned over the blood vessel to be occluded, and the jaws of the instrument are then closed to secure the clip to the blood vessel. The fixation of the clip is sufficient to provide a frictional engagement between the clip and the sides of the container, so that when the device is opened, the clip is attached to the container and away from the jaws of the device. Stays on blood vessels.

The clip of the present invention can be assembled into various sizes depending on the intended use. The hemostatic clip 1 typically has a length of less than Q111111, a width of 1 to 1.5III11, and a blood vessel clamping surface of about 31Illll in length. The 1J method of clips is used for specific purposes in microsurgery.
About 5096 can be lowered against gold)
.

It can be roughly twice the size of a relatively large lip (-#0) hemostatic clip for special hemostasis. The size of the God's clip is preferably compatible with the individual device being used, with the size of the clip adapted to represent the best σ) characteristics.

The clip of the present invention is conveniently molded from a biologically acceptable polymeric material that is either absorbable or non-absorbable in body tissue. Suitable absorbent polymers and copolymers include glycolide, lactide and poly(P)dioxanone polymers and copolymers. Suitable non-absorbable polymers include nylon, polyester and polypropylene. All of these materials are
It has been demonstrated to be biologically acceptable when used as a suture or other implantable medical device.

Clips can be sterilized by any conventional oral method, but the method of sterilization is generally related to the type of polymer used to make the clip. C1 is sterilized by heating or hot air sterilization, such as by indirect radiation M4 sterilization such as Kobal 1-Terukawa, electron beam heat Q1, etc., by C1 earthen A oxide sterilization, or by methods known in the art. Things can be done.

The clip of the present invention can be easily and economically manufactured by injection molding or other suitable lj processes known in the art.

Although the present invention and some specific embodiments thereof have been described herein, those skilled in the art will appreciate that without departing from the spirit of the invention,
It will be obvious that many changes and modifications can be made to the present invention.

[Brief explanation of the drawing]

FIG. 1 is an enlarged perspective view of the novel clip of the present invention in the interrogated position. FIG. 2 is an enlarged j9 close view of the clip of FIG. 1 closed around a blood vessel. FIG. 3 is a side view of an instrument for using the clip of the present invention. FIG. 4 is an enlarged perspective view showing the jaws of an instrument for using the clip of the present invention with the clip and jaws in the interrogated position. Procedure amendment (method) 1984r
-December 8, Mr. Kazuo Wakasugi, Commissioner of the Japan Patent Office1, Indication of the case, Patent Application No. 136933/1982, Name of the invention, Non-metallic, biocompatible hemostatic clip 3, Person making the amendment Relationship to the case Name of patent applicant Ethicon Incorporated 4, Agent
107 Address: 1-9-15 Akasaka, Minato-ku, Tokyo, Date of amendment order: November 29, 1982 (Shipping date): 6, Subject of amendment 1, Request ■ 1, Name of the invention Column 2゜A7 of the title of the invention in the description, content of amendment 1, as in the attached application for correction. 2. The name of the negative invention on the specification side is corrected to [Non-metallic, biocompatible hemostatic clip].

Claims (1)

Claims: 1. A sterile, hemostatic clip for occluding blood vessels, the clip comprising a pair of spaced apart legs having blood vessel clamping surfaces disposed in parallel and facing each other. one end of the leg member is open τ such that both blood vessel clamping surfaces can be placed on either side of the blood vessel to be occluded.
and the other ends of the leg members are joined by Nil Ni) possible means, whereby the spacing between the blood vessel clamping surfaces is adjusted to occlude the blood vessel placed between the vessel clamping surfaces. 1/+1 clip, characterized in that it can be lowered to a height of 1". 2. At least a portion of the four surfaces of both leg members are parallel to each other. Claim 1. A sterile hemostatic clip as described. 3. The adjustable means comprises a chain end attached from a blood vessel clamping surface at one end of one of the leg members, and a complementary pawl disposed at one end of the other leg member; A sterile hemostatic clip according to claim 1 or 2, wherein the pawl is such that it only allows movement to lower the H-corner between the blood vessel constricting surfaces of the leg member. 4. An absorbable hemostatic clip. Claim 1 consisting of a polymeric material.
Or fI described in Section 3! Sterile hemostatic clip. 5. The sterile hemostatic clip according to claim 4, wherein the retractable polymeric material is a copolymer of lactide and cricolide.