CN105101977A - 治疗心力衰竭的方法 - Google Patents

治疗心力衰竭的方法 Download PDF

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Publication number
CN105101977A
CN105101977A CN201480020281.5A CN201480020281A CN105101977A CN 105101977 A CN105101977 A CN 105101977A CN 201480020281 A CN201480020281 A CN 201480020281A CN 105101977 A CN105101977 A CN 105101977A
Authority
CN
China
Prior art keywords
nitrate
inorganic
heart failure
group
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201480020281.5A
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English (en)
Chinese (zh)
Inventor
胡利奥·A·奇里诺斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania Penn
Original Assignee
University of Pennsylvania Penn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pennsylvania Penn filed Critical University of Pennsylvania Penn
Publication of CN105101977A publication Critical patent/CN105101977A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
CN201480020281.5A 2013-02-07 2014-02-07 治疗心力衰竭的方法 Pending CN105101977A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361761863P 2013-02-07 2013-02-07
US61/761,863 2013-02-07
PCT/US2014/015300 WO2014124256A1 (en) 2013-02-07 2014-02-07 Methods of treating heart failure

Publications (1)

Publication Number Publication Date
CN105101977A true CN105101977A (zh) 2015-11-25

Family

ID=51300154

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480020281.5A Pending CN105101977A (zh) 2013-02-07 2014-02-07 治疗心力衰竭的方法

Country Status (6)

Country Link
US (1) US20150366901A1 (https=)
EP (1) EP2953631A4 (https=)
JP (1) JP6441818B2 (https=)
CN (1) CN105101977A (https=)
CA (1) CA2900526C (https=)
WO (1) WO2014124256A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160008394A1 (en) * 2013-02-28 2016-01-14 Aires Pharmaceuticals, Inc. Inorganic nitrite to improve cardiopulmonary hemodynamics
AU2018237816A1 (en) * 2017-03-23 2019-10-31 Mission Salt, Inc. Beetroot-containing composition
CA3060985A1 (en) 2017-04-21 2018-10-25 Northeast Ohio Medical University Vasodilators for treatment of heart failure
US10702796B2 (en) * 2017-09-13 2020-07-07 Thermolife International, Llc Enriched root powder products and methods of producing thereof
FI128489B (en) 2018-10-01 2020-06-15 Precordior Oy Equipment for generating information indicating cardiac abnormality

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101622005A (zh) * 2007-02-26 2010-01-06 乔恩·伦德伯格 亚硝酸根和硝酸根的新用途和包含它们的组合物
WO2012076667A1 (en) * 2010-12-08 2012-06-14 Solvotrin Innovations Limited Compounds for treatment of heart failure
US20120214818A1 (en) * 2009-09-11 2012-08-23 The Board Of Trustees Of The University Of Illinois Methods of treating diastolic dysfunction and related conditions
WO2012142413A2 (en) * 2011-04-14 2012-10-18 Theravasc Inc. Nitrite compositions and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2294543T3 (es) * 2003-07-09 2008-04-01 The Government Of The United States Of America, As Represented By The Secretary, Department Of Heal Uso de sales de nitrilo para el tratamiento de afecciones cardiovasculares.
US20120208762A1 (en) * 2009-10-27 2012-08-16 The Board Of Trustees Of The University Of Illinois Methods of Diagnosing Diastolic Dysfunction
US20160008394A1 (en) * 2013-02-28 2016-01-14 Aires Pharmaceuticals, Inc. Inorganic nitrite to improve cardiopulmonary hemodynamics

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101622005A (zh) * 2007-02-26 2010-01-06 乔恩·伦德伯格 亚硝酸根和硝酸根的新用途和包含它们的组合物
US20120214818A1 (en) * 2009-09-11 2012-08-23 The Board Of Trustees Of The University Of Illinois Methods of treating diastolic dysfunction and related conditions
WO2012076667A1 (en) * 2010-12-08 2012-06-14 Solvotrin Innovations Limited Compounds for treatment of heart failure
WO2012142413A2 (en) * 2011-04-14 2012-10-18 Theravasc Inc. Nitrite compositions and uses thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
SCOTT K. FERGUSON ET AL.: "Impact of dietary nitrate supplementation via beetroot juice on exercising muscle vascular control in rats", 《J PHYSIOL》 *
STEPHEN J. BAILEY ET AL.: "Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans", 《J APPL PHYSIOL》 *
VIKAS KAPIL ET AL.: "Inorganic Nitrate Supplementation Lowers Blood Pressure in Humans-Role for Nitrite-Derived NO", 《HYPERTENSION》 *

Also Published As

Publication number Publication date
EP2953631A4 (en) 2017-03-01
WO2014124256A1 (en) 2014-08-14
JP6441818B2 (ja) 2018-12-19
CA2900526C (en) 2021-05-04
EP2953631A1 (en) 2015-12-16
US20150366901A1 (en) 2015-12-24
JP2016507570A (ja) 2016-03-10
CA2900526A1 (en) 2014-08-14

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Application publication date: 20151125

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