CN105056022A - Medicament for treating liver cirrhosis - Google Patents
Medicament for treating liver cirrhosis Download PDFInfo
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- CN105056022A CN105056022A CN201510460093.0A CN201510460093A CN105056022A CN 105056022 A CN105056022 A CN 105056022A CN 201510460093 A CN201510460093 A CN 201510460093A CN 105056022 A CN105056022 A CN 105056022A
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Abstract
The invention relates to a medicament for treating liver cirrhosis, prepared from, by weight, 20 parts of giant knot weed, 30 parts of longtube ground ivy herb, 3 parts of glabrous greenbrier rhizome, 6 parts of common Curculigo rhizome, 5 parts of lawn pennywort herb, 2 parts of seed of nux-vomica poison nut, 2 parts of common rush, 1 part of blue Plantainlily herb, and 10 parts of Albizzia flower. The herbal materials, the giant knot weed used for dispelling wind-evil to remove dampness and dissipating blood stasis to stop pain, the longtube ground ivy herb used for removing dampness to treat stranguria, the glabrous greenbrier rhizome used for removing dampness and detoxifying, the common Curculigo rhizome used for tonifying kidney, reinforcing tendon and dispelling cold-damp, the lawn pennywort herb used for reducing fever and causing diuresis, the seed of nux-vomica poison nut used for activating blood and dissolving stasis, common rush used for clearing internal heat and promoting bowel movements, the blue Plantainlily herb used for dissipating blood stasis and detoxifying, and the Albizzia flower used for resolving stagnation for tranquilization, are combined to be effective in soothing liver, tonifying spleen, reinforcing kidney, and promoting blood and qi circulation and be effective in treating liver cirrhosis. Clinical testing shows that the medicament is safe and effective in treating liver cirrhosis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of medicine being used for the treatment of liver cirrhosis.
Background technology
Liver cirrhosis refers to that the various chronic disease long-run developments of liver cause hepatocellular degeneration, necrosis, the regeneration of secondary liver cell nodules shape and proliferation of fibrous tissue, these three kinds of pathological changes repeatedly to hocket, such that lobules of liver structure and blood circulation are reconstructed again, liver distortion, hardening.Be that posthepatitic cirrhosis, external chronic alcoholism are in the majority at China's great majority.But in the past few years along with the increase of people's drinking amount, China's sickness rate are in rising trend.
Medicine many uses hepatocyte growth factor, reduced glutathion, calcium channel blocker etc. of current western medical treatment liver cirrhosis.Particularly the utilization of recombinant human growth hormone also has the danger of induced tumor.
Medical material involved in the present invention is recorded in all as seen " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aim to provide a kind of be used for the treatment of liver cirrhosis medicine, by selecting suitable medical material and proportioning thereof, reaching the object of safe and effective healing liver cirrhosis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of medicine being used for the treatment of liver cirrhosis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Rhizoma Polygoni Cuspidati 20 parts, Herba Glechomae 30 parts, Rhizoma Smilacis Glabrae 3 parts, Rhizoma Curculiginis: 6 parts, Herba Hydrocotyles 5 parts, Semen Strychni 2 parts, Medulla Junci 2 parts, Flos hostae ventricosae 1 part, Flos Albiziae 10 parts.
Inventor thinks, liver is shaoyang within yin, liver person organ of general.Main catharsis, store blood.The ascending, descending, exiting and entering of liver main whole body gas, liver rise lung, and to fall then mechanism of qi unobstructed.Then there is the disease such as ascites, jaundice in the pent-up of abnormal liver function popularity, disorder of body fluid.The liver five elements are that wood is by lung (gold) restriction or checking relation in five elements, kidney (water) interpromoting relation in five elements.For treating the liver disease must conditioning lung and kidney two dirty.Again because liver (wood) gram spleen (soil), the weak spleen of liver are strong, so temperature adjusts spleen also to have the effect treating liver.
The present invention uses: Rhizoma Polygoni Cuspidati expelling wind and removing dampness, dissipating blood stasis analgesic therapy; Herba Glechomae dampness removing is treating stranguria; Rhizoma Smilacis Glabrae removing dampness and detoxicating; The strong muscle dispelling cold and dampness of Rhizoma Curculiginis the kidney invigorating; Herba Hydrocotyles clearing away heat and promoting diuresis; Semen Strychni blood circulation promoting and blood stasis dispelling; Medulla Junci relieves inflammation or internal heat convenient; Flos hostae ventricosae dissipating blood stasis detoxifies; Flos Albiziae resolving stagnation for tranquilization.All medicines share, and common long memorial liver spleen reinforces the kidney, effect of blood-activating and qi-promoting, effectively treats liver cirrhosis.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects liver cirrhosis patient 80 example for 2012 altogether between year December of December ~ 2014, all from hepatology outpatient service, and 22 ~ 50 years old age, man 45 example, female 30 example.The course of disease 3 months ~ 5 years.
Diagnostic criteria: 1. onset concealment, have weak, loss of appetite, abdominal distention, suffer from diarrhoea, become thin.2. hepatomegaly, edge are firmly, often nodositas, spider angioma, liver palm, splenomegaly, abdominal wall varicosis, ascites etc.3. anemia, platelet and leukocyte count is often had to reduce.Conjugated bilirubin, ALT, AST, GGT etc. increase, prolonged prothrombin, plasma albumin reduce, A/G ratio is inverted, alpha-fetoprotein increases.4. B ultrasonic can point out diagnosis.If esophageal barium meal perspective is shown in that the cirsoid x-ray positive is levied and also had decisive diagnostic significance.
Meet above-mentioned diagnostic criteria, patient that the age is greater than 18 years old.
Exclusion standard: trimester of pregnancy, women breast-feeding their children; Hepatic and renal function is abnormal or with serious primary disease etc.
2, test method
The decoct that the oral the present invention of all patients obtains according to embodiment 1, every day 3 times.6 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Judge according to " the sick efficacy assessment standard of liver cirrhosis ".
1. take a turn for the better: for general symptom improve, liver function is normal, ascites reduces and even disappears.
2. invalid: the state of an illness is unchanged before comparatively taking medicine.
3. do not heal: the state of an illness increases without improvement even deterioration, abnormal liver function, ascites and occurs jaundice.
3.2 therapeutic outcome
80 routine patients take a turn for the better 76 examples, invalid 4 examples, more 0 example.Total effective rate 95%.There is laxativeness in treatments period 2 example, has no other obvious adverse reaction.Visible the present invention be used for the treatment of liver cirrhosis safe and effective, there is the value applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Rhizoma Polygoni Cuspidati 20 grams, Herba Glechomae 30 grams, Rhizoma Smilacis Glabrae 3 grams, Rhizoma Curculiginis: 6 grams, Herba Hydrocotyles 5 grams, Semen Strychni 2 grams, Medulla Junci 2 grams, Flos hostae ventricosae 1 gram, Flos Albiziae 10 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of liver cirrhosis.Oral, every bu morning, noon and afternoon take for three times.
Embodiment 2
Take: Rhizoma Polygoni Cuspidati 20 grams, Herba Glechomae 30 grams, Rhizoma Smilacis Glabrae 3 grams, Rhizoma Curculiginis: 6 grams, Herba Hydrocotyles 5 grams, Semen Strychni 2 grams, Medulla Junci 2 grams, Flos hostae ventricosae 1 gram, Flos Albiziae 10 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of liver cirrhosis.Oral, daily once.
Embodiment 3
Take: Rhizoma Polygoni Cuspidati 20 grams, Herba Glechomae 30 grams, Rhizoma Smilacis Glabrae 3 grams, Rhizoma Curculiginis: 6 grams, Herba Hydrocotyles 5 grams, Semen Strychni 2 grams, Medulla Junci 2 grams, Flos hostae ventricosae 1 gram, Flos Albiziae 10 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of liver cirrhosis.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. one kind is used for the treatment of the medicine of liver cirrhosis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Rhizoma Polygoni Cuspidati 20 parts, Herba Glechomae 30 parts, Rhizoma Smilacis Glabrae 3 parts, Rhizoma Curculiginis: 6 parts, Herba Hydrocotyles 5 parts, Semen Strychni 2 parts, Medulla Junci 2 parts, Flos hostae ventricosae 1 part, Flos Albiziae 10 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510460093.0A CN105056022A (en) | 2015-07-30 | 2015-07-30 | Medicament for treating liver cirrhosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510460093.0A CN105056022A (en) | 2015-07-30 | 2015-07-30 | Medicament for treating liver cirrhosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105056022A true CN105056022A (en) | 2015-11-18 |
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ID=54485692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510460093.0A Pending CN105056022A (en) | 2015-07-30 | 2015-07-30 | Medicament for treating liver cirrhosis |
Country Status (1)
| Country | Link |
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| CN (1) | CN105056022A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0525054A (en) * | 1991-07-19 | 1993-02-02 | Nippon Oil & Fats Co Ltd | Hepatopathy-therapeutic/preventive agent |
| CN103223131A (en) * | 2013-05-13 | 2013-07-31 | 殷广全 | Liver disease drug |
-
2015
- 2015-07-30 CN CN201510460093.0A patent/CN105056022A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0525054A (en) * | 1991-07-19 | 1993-02-02 | Nippon Oil & Fats Co Ltd | Hepatopathy-therapeutic/preventive agent |
| CN103223131A (en) * | 2013-05-13 | 2013-07-31 | 殷广全 | Liver disease drug |
Non-Patent Citations (1)
| Title |
|---|
| 聂哲云: "中西医结合治疗肝硬化51例临床观察", 《现代中医药》 * |
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| C10 | Entry into substantive examination | ||
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20151118 |
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| WD01 | Invention patent application deemed withdrawn after publication |