CN105055846A - Sick sinus syndrome and drug for treating same - Google Patents

Abstract

The invention relates to a sick sinus syndrome and a drug for treating the same. According to the viewpoint of traditional Chinese medicines, the sick sinus syndrome is analyzed to belong to heart-kidney yang deficiency, qi and blood deficiency as well as wind-phlegm blocking collaterals and is treated by using a traditional Chinese medicine composition with the effects of nourishing and warming kidney-yang, tonifying qi and lifting yang, cooling blood and clearing heart, dispelling wind and reducing phlegm as well as stimulating the circulation of the blood and causing the muscles and joints to relax. The drug is prepared from 15 parts of radix codonopsis, 15 parts of salvia miltiorrhiza, 15 parts of astragalus, 7 parts of acorus calamus, 20 parts of radix rehmanniae, 15 parts of radix ophiopogonis, 15 parts of dragon teeth, 20 parts of alocasia, 15 parts of honeysuckles, 15 parts of safflowers, 20 parts of Chinese wax gourd peel, 10 parts of lucid ganoderma, 8 parts of wolfberry and 7 parts of liquorice. The drug is remarkable in taking effect, capable of treating both symptoms and root causes and stable in curative effect.

Description

Sick sinus syndrome and medicine thereof

Technical field

The present invention relates to disease too sinus syndrome and medicine thereof, particularly with the medicine of traditional Chinese medical herbal treatment, belong to medicine technology field.

Background technology

Sick sinus syndrome (sicksinussyndrome, SSS) be form obstacle because sinuatrial node or the former organic disease of its surrounding tissue cause sinuatrial node to be got excited, or the syndrome of multiple arrhythmia caused by sinuatrial node to atrium conduction of impulse obstacle and multiple symptom.Principal character is sinus bradycardia, is called bradycardia one tachycardia syndrome when merging tachyarrhythmia recurrent exerbation.Symptom is there is greatly more than more than 40 years old.The sick sinus syndrome cause of disease: by the sclerosis of cardiovascular idiopathic, degeneration, coronary heart disease, cardiomyopathy, myocarditis, rheumatic heart disease, surgical injury, hypertension etc. cause.Clinical manifestation: insidious onset, makes slow progress, and is sometimes chanced on.Can show effect lastingly or intermittently.Acute myocardial infarction of inferior wall and myocarditis, can cause temporary sinus node dysfunction, and acute stage is many disappearances in the past.When there is height sino atrial block or sinus arrest time serious, short battle array of can showing effect is fainted or blindness, occasionally angina pectoris, heart failure or shock etc. can occur, install type artificial cardiac pacemaker as required.Primary disease is on the basis continuing the slow rhythm of the heart, to have of short duration sinus arrhythmia outbreak.Compare with young people, gerontal patient has following characteristics: 1. binodal disease is common, sinuatrial node pathological changes causes significant sinus bradycardia, antrum subgroup four and sinus standstill, on this basis as (>=2s) or the junctional escape beat rhythm of the heart slowly (<35 time/min or companion atrioventricular block (AVB) person comparatively late appears in junctional escape beat, illustrate that pathological changes involves sinuatrial node and atrioventricular node, be called binodal disease.Old people's binodal disease obviously more than young people, prompting gerontal patient pathological changes extensively, be in a bad way.2. slow-fast syndrome is common: gerontal patient, on the basis continuing the slow rhythm of the heart, comparatively easily occurs of short duration tachy-arrhythmia (supraventricular tachycardia, room are flutterred, atrial fibrillation), atrial Lesions has been described, as with chamber or bundle-branch block, pointed out whole conducting system pathological changes.3. the heart, brain, renal ischaemia performance are more outstanding: rhythm of the heart <40min, often has the performance of internal organs blood supply insufficiency, the lighter is weak, dizzy, dim eyesight, insomnia, hypomnesis, bradykinesia, severe one generation A Si syndrome.

Sick sinus syndrome does not have special specific treatment medicine at present, mainly for the symptom treatment occurred.Heart rate slowly significantly or companion subjective symptoms person can try out atropine, salbutamol is oral.Binodal disease, brady tachy arrhythmia syndrome and have obvious brain blood should settle type artificial cardiac pacemaker as required for the patient of not enough symptom as intimate faintness or faintness, Atrioventricular sequence demand pacemaker comparatively VVI more meets physiological requirement.Merging tachy-arrhythmia, add again after pacemaker and control tachy-arrhythmia outbreak with medicine.Recently still useful program controlled automatic scanning conversion device treatment brady tachy arrhythmia syndrome (see artificial cardiac pacemaker chapter), presses VVI pace-making, then transfers VVT to by VVI during episode of tachycardia during bradycardia, and granting scanning stimulates or short battle array rapid stimulation stops episode of tachycardia.Patients With Sick Sinus Syndrome forbids the medicine of possibility decreased heart rate as depressor, anti-arrhythmic, cardiac tonic, beta-adrenergic blocking agent and calcium antagonist etc.When atrial fibrillation or atrial flutter outbreak, electrical conversion should not be carried out.Primary disease treatment difficulty, lacks the effectively medicine had no side effect because of to the slow rhythm of the heart, uses control tachy-arrhythmia medicine to increase the weight of again the rhythm of the heart slow, and when rapid heart rate transfers the slow rhythm of the heart to the heart beating dead time longer.Therefore, treatment primary disease should note 3 points: 1. the medicine of any raising rhythm of the heart can only do emergency managemnt, should not for a long time with 2. using symptom as selecting the foundation of therapeutic scheme, if any blindness, the ischemia symptom such as to faint of unknown cause, answers artificial cardiac pacemaker implantation.Old people installs VVI type pacemaker and pace-making syndrome easily occurs, and as pacing frequency slowed down, keeping the sinus rhythm of patient oneself as far as possible, can reduce its generation.3. should avoid before pacemaker using the medicine (verapamil, beta-blocker etc.) suppressing sinuatrial node.

Summary of the invention

Western medicine and assistive device are just for the symptom on sick sinus syndrome surface, and old complaint obtains can not be cured, and finally recurs.In order to overcome the limitation of Western medicine and assistive device, my invention sick sinus syndrome and medicine thereof, take treatment with Chinese medicine, can for the cause of disease, stable curative effect.

With Chinese medicine viewpoint analysis sick sinus syndrome, belong to deficiency of heart-YANG and kidney-YANG, insufficiency of vital energy and blood, obstruction of collateral caused by windphlegm, treatment should clear away heart-fire with warming and invigorating kidney deficiency, tonifying Qi and lifting yang, removing heat from blood, the Chinese medicine combined therapy of dispelling pathogenic wind and eliminating phlegm, soothing the channels and quicking the network vessels.Sick sinus syndrome and medicine thereof combine by each Chinese medicine quality part ratio below: Radix Codonopsis 15 parts, Radix Salviae Miltiorrhizae 15 parts, the Radix Astragali 15 parts, Rhizoma Acori Graminei 7 parts, 20 parts, the Radix Rehmanniae, Radix Ophiopogonis 15 parts, white Dens Draconis 15 parts, Rhizoma alcasiae odorae 20 parts, Flos Lonicerae 15 parts, 15 parts, Flos Carthami, Exocarpium Benincasae 20 parts, Ganoderma 10 parts, Fructus Lycii 8 parts, 7 parts, Radix Glycyrrhizae.

The property of medicine efficiency analysis of each Chinese medicine in sick sinus syndrome and medicine thereof: Radix Codonopsis is the conventional traditional tonic of China, has invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting; There is enhancing immunity, blood vessel dilating, blood pressure lowering, improve microcirculation, strengthen the effects such as hemopoietic function.Radix Salviae Miltiorrhizae bitter in the mouth, cold nature; GUIXIN, Liver Channel, energy promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, clear away heart-fire relieving restlessness, nourishing blood to tranquillize the mind; Cure mainly menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.The sweet temperature of the Radix Astragali, returns lung meridian, has tonifying Qi and lifting yang, a function that benefit defends consolidating superficial resistance; Modern medicine study shows, the Radix Astragali has enhancing human body immunity function, protects the liver, diuresis, antitumor.Rhizoma Acori Graminei effect: refreshment of having one's ideas straightened out, eliminating phlegm, ward off dirty, drying dampness to eliminate phlegm, clearing away phlegm, clear away heart-fire, tranquilizing the mind, be amusing, circulation of qi promoting is stagnant.Radix Rehmanniae clearing away heat and promoting production of body fluid, removing heat from blood, yin nourishing, hemostasis, for consumption of YIN caused by febrile disease, crimson tongue excessive thirst, sends out speckle dermexanthesis, spits blood, epistaxis, laryngopharynx swelling and pain.Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire, and for dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.White Dens Draconis and ancient times mammal fossil, demented for infantile convulsion, cardiopalmus, insomnia.Rhizoma alcasiae odorae is the plant of Araeceae Alocasia, and Chinese medicine is used as medicine with rhizome, and Taiwan claims husband's aunt taro, originate in South America, be a kind of common ornamental plant, have multiple being commonly called as, as, Rhizoma Alocasiae Odorae, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) are colored, Rhizoma Colocasiae antiquori is first-class, Rhizoma alcasiae odorae has severe toxicity, generally removes slag and takes soup, medicinal residues strong toxicity to decoct soup with medicinal, effect extra-heavy of Rhizoma alcasiae odorae dispelling pathogenic wind and eliminating phlegm, for tackling the pathogenic bacteria of some stubbornnesses.The potent medicine of Flos Lonicerae heat-clearing and toxic substances removing, antiviral, has the laudatory title of green antibiotic.Flos Carthami: promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving, controls amenorrhea ， mass in the abdomen, and difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.Exocarpium Benincasae clearing away heat and cooling blood, heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Ganoderma invigorating QI and tranquilization, relieving cough and asthma; For dizzy sleeplessness, shortness of breath and palpitation, asthenia cough with asthma; Ganoderma, for enhancing body immunity, regulates blood glucose, and control blood pressure, adjuvant therapy chemicotherapy, hepatoprotective, the aspects such as hypnotic all have significant curative effect.Fructus Lycii scalable body's immunity, can effectively Tumor suppression growth and cell mutation, there is the effect of the aspect such as slow down aging, anti-fatty liver, adjusting blood lipid and blood glucose, promotion hemopoietic function, and be applied to clinical.Radix Glycyrrhizae is the Chinese medicine applied simply widely, has many-sided effects such as invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, eliminating fire and detoxication, relieving spasm to stop pain, antiviral, coordinating the actions of various ingredients in a prescription.

The beneficial effect of sick sinus syndrome and medicine thereof is: in sick sinus syndrome and medicine thereof, sick sinus syndrome belongs to deficiency of heart-YANG and kidney-YANG with the theory analysis of Chinese medicine, insufficiency of vital energy and blood, obstruction of collateral caused by windphlegm, clear away heart-fire with warming and invigorating kidney deficiency, tonifying Qi and lifting yang, removing heat from blood, the Chinese medicine combined therapy of dispelling pathogenic wind and eliminating phlegm, soothing the channels and quicking the network vessels, theory of medicine is correct, puts into practice evident in efficacy, treating both the principal and secondary aspects of a disease, stable curative effect.

Detailed description of the invention

Sick sinus syndrome and medicine thereof combine by each Chinese medicine quality part ratio below: Radix Codonopsis 15 parts, Radix Salviae Miltiorrhizae 15 parts, the Radix Astragali 15 parts, Rhizoma Acori Graminei 7 parts, 20 parts, the Radix Rehmanniae, Radix Ophiopogonis 15 parts, white Dens Draconis 15 parts, Rhizoma alcasiae odorae 20 parts, Flos Lonicerae 15 parts, 15 parts, Flos Carthami, Exocarpium Benincasae 20 parts, Ganoderma 10 parts, Fructus Lycii 8 parts, 7 parts, Radix Glycyrrhizae.According to the mass parts ratio of sick sinus syndrome and medicine thereof, being suitable for a dose drug amount that a Sick Sinus Syndrome takes is by each Chinese medicine quality composition below: Radix Codonopsis 15 grams, Radix Salviae Miltiorrhizae 15 grams, the Radix Astragali 15 grams, Rhizoma Acori Graminei 7 grams, 20 grams, the Radix Rehmanniae, Radix Ophiopogonis 15 grams, white Dens Draconis 15 grams, Rhizoma alcasiae odorae 20 grams, Flos Lonicerae 15 grams, 15 grams, Flos Carthami, Exocarpium Benincasae 20 grams, Ganoderma 10 grams, Fructus Lycii 8 grams, 7 grams, Radix Glycyrrhizae.Instructions of taking: by each Effect of Chinese Medicine Qing wash clean, decoct soup and take soup orally, takes dose in one day, and serveing on a week is a course for the treatment of, alleviates and slightly subtract dose or take frequency after the course for the treatment of by the state of an illness.

Claims (1)

1. sick sinus syndrome and medicine thereof, is characterized in that combining by each Chinese medicine quality part ratio below: Radix Codonopsis 15 parts, Radix Salviae Miltiorrhizae 15 parts, the Radix Astragali 15 parts, Rhizoma Acori Graminei 7 parts, 20 parts, the Radix Rehmanniae, Radix Ophiopogonis 15 parts, white Dens Draconis 15 parts, Rhizoma alcasiae odorae 20 parts, Flos Lonicerae 15 parts, 15 parts, Flos Carthami, Exocarpium Benincasae 20 parts, Ganoderma 10 parts, Fructus Lycii 8 parts, 7 parts, Radix Glycyrrhizae.