CN105055708A - Medicine for treating nephritis - Google Patents

Medicine for treating nephritis Download PDF

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Publication number
CN105055708A
CN105055708A CN201510450284.9A CN201510450284A CN105055708A CN 105055708 A CN105055708 A CN 105055708A CN 201510450284 A CN201510450284 A CN 201510450284A CN 105055708 A CN105055708 A CN 105055708A
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China
Prior art keywords
parts
medicine
nephritis
rhizoma alismatis
herba pyrolae
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CN201510450284.9A
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Chinese (zh)
Inventor
吴斌
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Individual
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Individual
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Priority to CN201510450284.9A priority Critical patent/CN105055708A/en
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Abstract

The invention relates to a medicine for treating nephritis. The medicine is prepared from the following medicinal raw materials in parts by weight: 40 parts of codonopsis pilosula, 30 parts of astragalus membranaceus, 10 parts of rhizoma alismatis, 6 parts of gynostemma pentaphylla, 6 parts of cassia bark, 5 parts of herba pyrolae, 10 parts of Siwakuai and 8 parts of flos cleistocalycis. According to the medicine disclosed by the invention, the codonopsis pilosula is capable of tonifying middle-Jiao and qi, strengthening spleen and tonifying lung; the astragalus membranaceus is capable of invigorating qi for strengthening superficies, inducing diuresis and expelling toxin; the rhizoma alismatis has functions of inducing urination and clearing damp and hot; the gynostemma pentaphylla is effective in clearing away heat and toxic materials; the cassia bark is capable of tonifying fire and helping yang; the herba pyrolae has functions of clearing dampness, strengthening muscles and bones, and stopping bleeding; the Siwakuai is capable of resolving toxin and dispersing swelling; and the flos cleistocalycis is effective in expelling dampness and relieving stagnation. The medicine, by combining the medicinal raw materials, is capable of regulating triple energizer, and has functions of tonifying the kidney, invigorating spleen and clearing lung so as to effectively treat nephritis. Clinical experiments prove that the medicine disclosed by the invention can be used for safely and effectively treating nephritis.

Description

A kind of medicine being used for the treatment of nephritis
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of medicine being used for the treatment of nephritis.
Background technology
Glomerulonephritis is one group of allergic disease based on glomerular epithelial cell, is called for short nephritis.Clinical main manifestations has the change, edema, hypertension etc. of urine.The cause of disease of this disease and pathogenesis doctor trained in Western medicine do not provide to be explained completely, and a large amount of experiments and clinical research are thought to be caused by immune factor, are mainly allergy.Common with young man.First the patient of 40% finds hematuria and seeks medical advice; There is edema in the case of 90%, sees the puffiness of the eyes after the lighter rises morning, and severe one edema is prolonged and whole body.Even occur hydrothorax, ascites, occur out of breath and abdominal distention, some patients's blood pressure raises and has headache, and urine chemical examination is nearly all containing protein (albuminuria).
Current western medical treatment nephritis mostly is symptomatic treatment, does not have specific drug.With prevention of water, sodium retention, controlled circulation blood volume, thus reach mitigation symptoms, prevention lethal complication, renal function protecting are main.Medication multiselect thiazide diuretic, vasodilator, ganglionic block agents, calcium ion channel blocker etc.Severe patient uses dialysis treatment.But all cure the symptoms, not the disease, a tax on one's mind act of losing money.
Medical material involved in the present invention is recorded in all as seen " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of medicine being used for the treatment of nephritis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing nephritis.
In order to achieve the above object, the present invention is by the following technical solutions:
Be used for the treatment of a medicine for nephritis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix Codonopsis 40 parts, the Radix Astragali 30 parts, Rhizoma Alismatis 10 parts, Herb Gynostemmae Pentaphylli 6 parts, Cortex Cinnamomi 6 parts, Herba Pyrolae 5 parts, four tile fragment 10 parts, Flos Cleistocalycis Operculati 8 parts.
Inventor thinks: the formation of this disease is relevant with the dirty functional disorder of lung spleen kidney three.It is source on water that lung occupies the part of the body cavity above the diaphragm housing the heart and lungs; The main transmitting and distributing the fluids of the spleen being located in middle-JIAO; Kidney occupies the main water of the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels and takes charge of out entire.Three burnt unfavorable be the first cause of this disease.Only have and this three is dirtyly carried out to conditioning simultaneously and can cure this disease.
The present invention uses: Radix Codonopsis invigorating the spleen and replenishing QI, spleen invigorating lung benefiting; Radix Astragali invigorating QI to consolidate the body surface resistance, diuresis poison holding; Rhizoma Alismatis diuresis, clearing away damp-heat; Herb Gynostemmae Pentaphylli heat-clearing and toxic substances removing; It is supporing yang that Cortex Cinnamomi mends fire; The strong muscle hemostasis of Herba Pyrolae damp eliminating; Four tile fragment removing toxic substances and promoting subsidence of swelling; Flos Cleistocalycis Operculati dry disappear stagnant.All medicines share, and play the three burnt people having the same aspiration and interest altogether, effect of Yishen Jianpi lung heat clearing, effectively treats nephritis.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects nephritis patient 80 example for 2012 altogether between year December of December ~ 2014, all from Urology Department outpatient service, and 25 ~ 50 years old age, man 45 example, female 35 example.The course of disease 2 weeks ~ 1 year.
Diagnostic criteria:
The change of urine: have hematuria mostly to be gross hematuria, and occur rapidly oliguria, anuria.
Edema: normal very remarkable.Hypertension: continue raises more.
Other: occurring the interstitial pneumonia symptoms such as cough, hemoptysis, is goodpasture syndrome.
Lab testing: 1. urinating chemical examination has High-grade Proteinuria, Urine sediments analyzer visible red cell, leukocyte and various cast 2. routine blood test chemical examination have anemia 3. plasma protein reduction, and blood urea nitrogen, creatinine raise, CO2 combining power, CO2 CP reduction etc.
Meet the patient of above-mentioned diagnostic criteria.
Exclusion standard: trimester of pregnancy, women breast-feeding their children; Hepatic and renal function is abnormal or with serious primary disease etc.
2, test method
The decoct that the oral the present invention of all patients obtains according to embodiment 1, every day 3 times.6 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Judge according to " nephritis efficacy assessment standard ".
1. complete incidence graph symptom and positive sign disappear completely, and urine protein and erythrocyte continue to turn out cloudy, urine protein quantitation < 0.2/24h, and graft function keeps normal, continues more than 3 months.
2. basic relief of symptoms and positive sign disappear substantially, and urine protein and erythrocyte comparatively treat front minimizing >=50%, graft function or keep normal, or SCr is unchanged or raise < 50% compared with basic value, continues more than 3 months.
3. effectively symptom and positive sign are clearly better, urine protein and (or) erythrocyte comparatively treats front minimizing >=25%, renal function improves and continues more than 3 months, and SCr comparatively basic value raises < 100%.
4. invalid clinical manifestation and lab testing are without improvement.
3.2 therapeutic outcome
80 routine patient's complete incidence graph 60 examples, basic alleviation 14 example, invalid 4 examples.Total effective rate 95%.There is laxativeness in treatments period 2 example, has no other obvious adverse reaction.It is safe and effective that visible the present invention is used for the treatment of nephritis, has the value applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Radix Codonopsis 40 grams, the Radix Astragali 30 grams, Rhizoma Alismatis 10 grams, Herb Gynostemmae Pentaphylli 6 grams, Cortex Cinnamomi 6 grams, Herba Pyrolae 5 grams, four tile fragment 10 grams, Flos Cleistocalycis Operculati 8 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of nephritis.Oral, every bu morning, noon and afternoon take for three times.
Embodiment 2
Take: Radix Codonopsis 40 grams, the Radix Astragali 30 grams, Rhizoma Alismatis 10 grams, Herb Gynostemmae Pentaphylli 6 grams, Cortex Cinnamomi 6 grams, Herba Pyrolae 5 grams, four tile fragment 10 grams, Flos Cleistocalycis Operculati 8 grams; Add 10 times of water gagings, decoct 2 hours, filtration; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of nephritis.Oral, daily once.
Embodiment 3
Take: Radix Codonopsis 40 grams, the Radix Astragali 30 grams, Rhizoma Alismatis 10 grams, Herb Gynostemmae Pentaphylli 6 grams, Cortex Cinnamomi 6 grams, Herba Pyrolae 5 grams, four tile fragment 10 grams, Flos Cleistocalycis Operculati 8 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of nephritis.Oral, every bu is taken for twice sooner or later.

Claims (4)

1. be used for the treatment of a medicine for nephritis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix Codonopsis 40 parts, the Radix Astragali 30 parts, Rhizoma Alismatis 10 parts, Herb Gynostemmae Pentaphylli 6 parts, Cortex Cinnamomi 6 parts, Herba Pyrolae 5 parts, four tile fragment 10 parts, Flos Cleistocalycis Operculati 8 parts.
2. be used for the treatment of the medicine of nephritis as claimed in claim 1, it is characterized in that, its preparation method is: take: Radix Codonopsis 40 parts, the Radix Astragali 30 parts, Rhizoma Alismatis 10 parts, Herb Gynostemmae Pentaphylli 6 parts, Cortex Cinnamomi 6 parts, Herba Pyrolae 5 parts, four tile fragment 10 parts, Flos Cleistocalycis Operculati 8 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of the medicine of nephritis as claimed in claim 1, it is characterized in that, its preparation method is: take: Radix Codonopsis 40 parts, the Radix Astragali 30 parts, Rhizoma Alismatis 10 parts, Herb Gynostemmae Pentaphylli 6 parts, Cortex Cinnamomi 6 parts, Herba Pyrolae 5 parts, four tile fragment 10 parts, Flos Cleistocalycis Operculati 8 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filtration; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of the medicine of nephritis as claimed in claim 1, it is characterized in that, its preparation method is: take: Radix Codonopsis 40 parts, the Radix Astragali 30 parts, Rhizoma Alismatis 10 parts, Herb Gynostemmae Pentaphylli 6 parts, Cortex Cinnamomi 6 parts, Herba Pyrolae 5 parts, four tile fragment 10 parts, Flos Cleistocalycis Operculati 8 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
CN201510450284.9A 2015-07-28 2015-07-28 Medicine for treating nephritis Pending CN105055708A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105616617A (en) * 2016-02-29 2016-06-01 张向华 Medicine for treating acute glomerulonephritis
CN109316494A (en) * 2017-07-31 2019-02-12 何晓燕 Purposes of the badger seed oil in preparation treatment ephritis medicine or health food

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101623458A (en) * 2008-07-11 2010-01-13 北京天科仁祥医药科技有限公司 Chinese medicament preparation for clearing away heat and promoting diuresis, and removing damp and toxin and preparation method thereof
CN102430015A (en) * 2011-12-13 2012-05-02 朱友文 Traditional Chinese medicinal preparation for treating nephritis and uremia as well as preparation method thereof
CN103301245A (en) * 2013-06-03 2013-09-18 安徽华佗国药股份有限公司 Medicament for reinforcing qi, nourishing blood and nourishing liver and kidney
CN104353047A (en) * 2014-11-24 2015-02-18 时成伍 Traditional Chinese medicine for treating nephritis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101623458A (en) * 2008-07-11 2010-01-13 北京天科仁祥医药科技有限公司 Chinese medicament preparation for clearing away heat and promoting diuresis, and removing damp and toxin and preparation method thereof
CN102430015A (en) * 2011-12-13 2012-05-02 朱友文 Traditional Chinese medicinal preparation for treating nephritis and uremia as well as preparation method thereof
CN103301245A (en) * 2013-06-03 2013-09-18 安徽华佗国药股份有限公司 Medicament for reinforcing qi, nourishing blood and nourishing liver and kidney
CN104353047A (en) * 2014-11-24 2015-02-18 时成伍 Traditional Chinese medicine for treating nephritis

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105616617A (en) * 2016-02-29 2016-06-01 张向华 Medicine for treating acute glomerulonephritis
CN109316494A (en) * 2017-07-31 2019-02-12 何晓燕 Purposes of the badger seed oil in preparation treatment ephritis medicine or health food

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