CN105055484B - A kind of drug and its application method for treating acne - Google Patents

A kind of drug and its application method for treating acne Download PDF

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CN105055484B
CN105055484B CN201510556901.3A CN201510556901A CN105055484B CN 105055484 B CN105055484 B CN 105055484B CN 201510556901 A CN201510556901 A CN 201510556901A CN 105055484 B CN105055484 B CN 105055484B
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parts
vitamin
drug
baiyao
black powder
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CN105055484A (en
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陈静
吴坷沅
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Abstract

The present invention relates to a kind of drug and its application method for treating acne, the drug includes internal modulation agent and liniment, and the internal modulation agent includes the root of Dahurain angelica, zinc sulfate, campanulaceae and vitamin B;The liniment includes baiyao and black powder, and the white the effective elements of the medicine includes stearic acid, caustic potash, glycerol, ethylparaben, water, vitamin A acid and flagyl;The black the effective elements of the medicine includes rheum officinale, sulphur, almond, gingko and litharge.The interior curative effect of medication adjusted plus be applied with of the present invention is significant and easy to use, and has cosmetic result, has market popularization value.

Description

A kind of drug and its application method for treating acne
Technical field
The present invention relates to one of field of medicaments acne drugs, and in particular to drug and external drug joint are adjusted in a kind of The drug and its application method of the treatment acne used.
Background technique
Acne be it is a kind of mostly occur in face, chest, back pilosebaceous chronic inflammation disease, mostly occur in blueness Teenager, therefore it is called work " whelk ".Most people gave birth to acne, sank if dealing with improperly and often forming scar, tumour, pigment , influence beauty.Although currently, in the market about treatment acne drug and medicine adornment it is dazzling, had acne experience People both know about, really effective drug is fewer and fewer, and is easy recurrence.
Summary of the invention
The object of the present invention is to provide a kind of drugs and its application method for treating acne.The purpose of the present invention is by with Lower technical solution is realized:
A kind of drug for treating acne, it is characterised in that: the drug includes internal modulation agent and liniment, the interior tune Preparation includes the root of Dahurain angelica, zinc sulfate, campanulaceae and vitamin B;The liniment includes baiyao and black powder, the baiyao it is effective at Divide includes stearic acid, caustic potash, glycerol, ethylparaben, vitamin A acid and flagyl;It is the stearic acid, caustic potash, sweet Oil, ethylparaben, vitamin A acid and flagyl need to be tuned into water thick, and the black the effective elements of the medicine includes Rheum officinale, sulphur, almond, gingko and litharge.
Further, in the internal modulation agent various compositions parts by weight are as follows: 2~4 parts of the root of Dahurain angelica, 1~3 part of zinc sulfate, 1~6 part and 3~11 parts of vitamin B of campanulaceae;The parts by weight of various compositions in the baiyao are as follows: 13-20 parts of stearic acid, causticity 0.1-0.8 parts of potassium, 4~10 parts of glycerol, 0.1~1 part of ethylparaben, 6~8 parts of vitamin A acid and 3~6 parts of flagyl; The parts by weight of various compositions in the black powder are as follows: 12~16 parts of rheum officinale, 3~6 parts of sulphur, 2~5 parts of almond, 8~13 parts of gingko And 1~3 part of litharge.
Further, in the internal modulation agent various compositions parts by weight are as follows: 4 parts of the root of Dahurain angelica, 1 part of zinc sulfate, 5 parts of campanulaceae With 10 parts of vitamin B;The parts by weight of various compositions in the baiyao are as follows: 13 parts of stearic acid, 0.5 part of caustic potash, 5 parts of glycerol, 0.1 part of ethylparaben, 6 parts of vitamin A acid and 3 parts of flagyl;The parts by weight of various compositions in the black powder are as follows: big 14 parts yellow, 5 parts of sulphur, 3.5 parts of almond, 10 parts of gingko and 2 parts of litharge.
Further, the internal modulation agent is oral preparation;The vitamin B is vitamin B6.
Further, the various composition in the black powder is powdered.The baiyao and black powder are separately applied with, and this is white Medicine and black powder are to be tuned into paste body shape with water to be applied with again.
A kind of application method of the drug of the treatment acne, the application method are as follows: 1. baiyao: it weighs in proportion firmly Then resin acid, caustic potash, glycerol, Tretinoin, flagyl and ethylparaben are tuned into paste body shape or thick, external application with water At acne;2. black powder: weighing rheum officinale, sulphur, almond, gingko and litharge in proportion, and these ingredients are ground to carefully End is tuned into thick or paste body shape with water, is externally applied at acne;3. internal modulation agent: take in proportion the root of Dahurain angelica, zinc sulfate, campanulaceae and Vitamin B6;4. be applied with include include baiyao and black powder the course for the treatment of of liniment in, to take internal modulation agent simultaneously.
Further, the number that the baiyao is applied with daily is 3 times;The number that the black powder is applied with daily is 1 time, preferably Ground, the black powder are to be applied with once before sleeping daily.The internal modulation agent is daily 1~2 time, and white in internal modulation agent The root of Dahurian angelica, zinc sulfate, campanulaceae and vitamin B6 will be taken simultaneously.
The present invention provides a kind of drug and its application method for treating acne, this is mainly had the beneficial effect that The invention interior tune adds the curative effect of medication of external application significant, it is not easy to recur, and easy to use, and have cosmetic result, have Market popularization value.
Specific embodiment
A kind of drug and its application method for treating acne described in the embodiment of the present invention.It is with specific experiment case below Example illustrates specific embodiment, it should be understood that the specific embodiments described herein are merely illustrative of the present invention, and do not have to It is of the invention in limiting.
Embodiment 1
The parts by weight of various compositions in the internal modulation agent are as follows: 1. root of Dahurain angelica 4g, zinc sulfate 1g, campanulaceae 6g and vitamin B 4g;2. root of Dahurain angelica 3g, zinc sulfate 2g, campanulaceae 4g and vitamin B 8g;3. root of Dahurain angelica 7g, zinc sulfate 1g, campanulaceae 5g and vitamin B 10g.4. root of Dahurain angelica 2g, zinc sulfate 3g, campanulaceae 1g and vitamin B 11g;5. root of Dahurain angelica 4g, zinc sulfate 1g, campanulaceae 6g and vitamin B 3g;
As further preferred embodiment, the internal modulation agent is oral preparation;The vitamin B is vitamin B6。
Embodiment 2
The parts by weight of various compositions in the baiyao are as follows: 1. stearic acid 13g, caustic potash 0.8g, glycerol 4g, nipalgin second Ester 1g, vitamin A acid 6g and flagyl 6g;2. stearic acid 20g, caustic potash 0.1g, glycerol 10g, ethylparaben 0.1g, Vitamin A acid 8g and flagyl 3g;3. stearic acid 16g, caustic potash 0.4g, glycerol 7g, ethylparaben 0.5g, vitamin A acid 7g and flagyl 4g;4. stearic acid 13g, caustic potash 0.5g, glycerol 5g, ethylparaben 0.1g, vitamin A acid 6g And flagyl 3g.
The parts by weight of various compositions in the black powder are as follows: 1. rheum officinale 12g, sulphur 6g, almond 2g, gingko 13g and close Top monk 1g.2. rheum officinale 16g, sulphur 3g, almond 5g, gingko 8g and litharge 3g;3. the weight of various compositions in the black powder Number are as follows: rheum officinale 14g, sulphur 5g, almond 3.5g, gingko 10g and litharge 2g;4. rheum officinale 13g, sulphur 5g, almond 4g, white Fruit 12g and litharge 2.5g;5. 14 parts of rheum officinale, 5 parts of sulphur, 3.5 parts of almond, 10 parts of gingko and 2 parts of litharge.
As further preferred embodiment, the baiyao and black powder are separately applied with, and the baiyao and black powder are use Water is tuned into paste body shape and is applied with again.
Embodiment 3
The application method for treating the drug of acne are as follows: 1. baiyao: stearic acid, caustic potash, glycerol, vitamin are weighed in proportion Then A acid, flagyl and ethylparaben are tuned into paste body shape or thick with water, are externally applied at acne;2. black powder: pressing Ratio weighs rheum officinale, sulphur, almond, gingko and litharge, and these ingredients are ground to smalls, with water be tuned into it is thick or Paste body shape is externally applied at acne;3. internal modulation agent: taking the root of Dahurain angelica, zinc sulfate, campanulaceae and vitamin B6 in proportion;4. being wrapped being applied with In the course for the treatment of for including the liniment including baiyao and black powder, internal modulation agent is taken simultaneously.
The ratio of various compositions is the same as summary of the invention and embodiment in baiyao, black powder and internal modulation agent in the present embodiment 1 is consistent with the ratio in 2, is not repeating to limit here.
As further preferred embodiment, the number that the baiyao is applied with daily is 3 times;The black powder is applied with daily Number be 1 time, and preferably, black powder be applied with before sleeping daily it is primary.
As further preferred embodiment, the internal modulation agent is daily 1~2 time, preferably one time a day, and The root of Dahurain angelica, zinc sulfate, campanulaceae and vitamin B6 in internal modulation agent will be taken simultaneously.
As further preferred embodiment, the various composition in the black powder is powdered.
Embodiment 4
1. experimental group: interior tune+external application uses the drug for the treatment of acne of the invention to be treated for patients with acne: suffering from Person 331, wherein male 32 female 299;It is 12 years old the smallest in year, maximum 49 years old;20~40 years old account for 80%.These patients It is daily internal modulation agent 2 times, once in the morning and once at night;And affected part is externally applied to 3 times using baiyao daily, respectively early, in, Evening, and affected part is externally applied to 1 time with black powder before sleeping daily.
2. control group: being applied with, patient 100, wherein male 11 female 89;Age is 12 years old the smallest, and maximum 51 years old, person It in 100 patients, accounts for 32% within 12~19 years old, accounts for 65% within 20~40 years old.These patients are to be externally applied to daily using baiyao Affected part 3 times, it is respectively early, middle and late, and with black powder affected part is externally applied to 1 time before sleeping daily.
Above-mentioned two groups of patients are without chronic disease, and the equal non-pregnancy of female patient, stadium is in March~20 year, wherein 2 Year or more patient account for 80%.Above-mentioned two groups of patients have treated 2 months.As a result as shown in the table.
Note: it fully recovers for skin lesion recession 100%;It is almost recovered to subside for skin lesion and is greater than 95%;It is effective for skin lesion subside 70~ 94%;It is effectively skin lesion recession 40~69%;It is in vain that skin lesion is unchanged or recession is less than 40%.
From the foregoing, it will be observed that i.e. internal modulation agent and liniment is treated simultaneously using the drug for the treatment of acne of the present invention, Its curative effect highly significant, cure rate reaches 97%, and the skin lesion extinction rate of the patient of others 3% is between 70~94%; As long as the effect of the drug is apparently higher than simple liniment and is applied with.
It is found in treatment from above-mentioned experimental group (interior to adjust plus be applied with) with control group (external application), the cure rate of interior tune+external application Reach 97%, and the skin lesion extinction rate of the patient of others 3% is between 70~94%;And only with external application, it has control group Efficiency is only 37%, and the cure rate of experimental group is apparently higher than control group.It is statistically analyzed to obtain X2> 6.635, P < 0.01, Drug i.e. of the invention has highly significant effect.
The baiyao of external application is without any side effects, can be used as cosmetics or skin care item use.
When specifically used, as long as use in accordance with the method for the present invention, between baiyao, black powder and internal modulation agent Time interval etc. there is no particular/special requirement.
The present invention is not limited to above-mentioned preferred forms, anyone is made related of the invention under the inspiration of the present invention Any modification or change, it is all have technical solution identical or similar to the present application, all fall within protection model of the invention Within enclosing.

Claims (5)

1. a kind of drug for treating acne, it is characterised in that: the drug includes internal modulation agent and liniment, the internal modulation Agent is oral preparation;
The internal modulation agent includes the root of Dahurain angelica, zinc sulfate, campanulaceae and vitamin B;
The liniment includes baiyao and black powder, and the white the effective elements of the medicine includes stearic acid, caustic potash, glycerol, Ni Bo Golden ethyl ester, vitamin A acid and flagyl;The black the effective elements of the medicine includes rheum officinale, sulphur, almond, gingko and close Top monk;
The parts by weight of various composition in the internal modulation agent are as follows: 2~4 parts of the root of Dahurain angelica, 1~3 part of zinc sulfate, 1~6 part of campanulaceae and Vitamin B3~11 part;The parts by weight of various composition in the baiyao are as follows: 13-20 parts of stearic acid, 0.1-0.8 parts of caustic potash, 4~10 parts of glycerol, 0.1~1 part of ethylparaben, 6~8 parts of vitamin A acid and 3~6 parts of flagyl;It is each in the black powder The parts by weight of kind ingredient are as follows: 12~16 parts of rheum officinale, 3~6 parts of sulphur, 2~5 parts of almond, 8~13 parts of gingko and litharge 1 ~3 parts.
2. the drug for the treatment of acne according to claim 1, it is characterised in that: various composition in the internal modulation agent Parts by weight are as follows: 4 parts of the root of Dahurain angelica, 1 part of zinc sulfate, 5 parts of campanulaceae and vitaminB10 part;The parts by weight of various composition in the baiyao Number are as follows: 13 parts of stearic acid, 0.5 part of caustic potash, 5 parts of glycerol, 0.1 part of ethylparaben, 6 parts of vitamin A acid and flagyl 3 Part;The parts by weight of various composition in the black powder are as follows: 14 parts of rheum officinale, 5 parts of sulphur, 3.5 parts of almond, 10 parts of gingko and close 2 parts of top monk.
3. the drug for the treatment of acne according to claim 1 or 2, it is characterised in that: the vitamin B is vitamin B6.
4. the drug for the treatment of acne according to claim 3, it is characterised in that: the various composition in the black powder is powder Last shape.
5. the drug for the treatment of acne according to claim 4, it is characterised in that: the baiyao and black powder are separately applied with, and The baiyao and black powder are to be tuned into paste body shape with water to be applied with again.
CN201510556901.3A 2015-09-02 2015-09-02 A kind of drug and its application method for treating acne Active CN105055484B (en)

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Publication number Priority date Publication date Assignee Title
WO2017210239A1 (en) * 2016-05-31 2017-12-07 L'oreal Anti-acne compositions and methods of use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102451108A (en) * 2010-10-28 2012-05-16 张兰珍 Emulsifiable paste for removing acnes
CN102552563A (en) * 2011-11-12 2012-07-11 马海波 Medicament for treating acne

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102451108A (en) * 2010-10-28 2012-05-16 张兰珍 Emulsifiable paste for removing acnes
CN102552563A (en) * 2011-11-12 2012-07-11 马海波 Medicament for treating acne

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