CN105055484A - Medicine for treating acne and application method thereof - Google Patents
Medicine for treating acne and application method thereof Download PDFInfo
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- CN105055484A CN105055484A CN201510556901.3A CN201510556901A CN105055484A CN 105055484 A CN105055484 A CN 105055484A CN 201510556901 A CN201510556901 A CN 201510556901A CN 105055484 A CN105055484 A CN 105055484A
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Abstract
The invention relates to a medicine for treating acne and an application method thereof. The medicine comprises an internal adjustment preparation and an external application medicine, wherein the internal adjustment preparation comprises angelica, zinc sulfate, balloon flower and vitamin B; the external application medicine comprises a white medicine and a black medicine, wherein the white medicine comprises stearic acid, potassium hydroxide, glycerol, ethylparaben, water, vitamin A acid and metronidazole as effective ingredients; the black medicine comprises rhubarb, sulfur, almond, ginkgo and litharge as effective ingredients. The medicine comprising the internal adjustment preparation and the external application medicine, provided by the invention, is obvious in curative effect and convenient to use, has a beautifying effect and has market popularization values.
Description
Technical field
The present invention relates to a kind of acne medicine in field of medicaments, be specifically related to medicine and the application process thereof of the Acne treatment of a kind of interior tune medicine and external used medicine conbined usage.
Background technology
Acne is a kind of multiple disease of pilosebaceous chronic inflammation of being born in face, breast, the back of the body, is multiplely born in teenager, therefore is called again " comedo ".Most people gave birth to acne, often formed cicatrix, cyst, pigmentation if dealt with improperly, impact beauty treatment.At present, although on market about the medicine of Acne treatment and medicine adornment a feast for the eyes, the people having acne to experience knows, real effective medicine is few, and easily recurs.
Summary of the invention
The object of this invention is to provide a kind of medicine and application process thereof of Acne treatment.The object of the invention is to be achieved through the following technical solutions:
A medicine for Acne treatment, is characterized in that: described medicine comprises internal modulation agent and liniment, and described internal modulation agent comprises the Radix Angelicae Dahuricae, zinc sulfate, Radix Platycodonis and vitamin B; Described liniment comprises BAIYAO and black powder, and described white the effective elements of the medicine comprises stearic acid, caustic potash, glycerol, ethyl hydroxybenzoate, retinoic acid and metronidazole; This stearic acid, caustic potash, glycerol, ethyl hydroxybenzoate, retinoic acid and metronidazole need with water furnishing thick, and described black the effective elements of the medicine comprises Radix Et Rhizoma Rhei, sulfur, Semen Armeniacae Amarum, Semen Ginkgo and Lithargyrum.
Further, in described internal modulation agent, the parts by weight of various composition are: the Radix Angelicae Dahuricae 2 ~ 4 parts, 1 ~ 3 part, zinc sulfate, Radix Platycodonis 1 ~ 6 part and vitamin B3 ~ 11 part; In described BAIYAO, the parts by weight of various composition are: stearic acid 13-20 part, caustic potash 0.1-0.8 part, glycerol 4 ~ 10 parts, ethyl hydroxybenzoate 0.1 ~ 1 part, retinoic acid 6 ~ 8 parts and metronidazole 3 ~ 6 parts; In described black powder, the parts by weight of various composition are: Radix Et Rhizoma Rhei 12 ~ 16 parts, 3 ~ 6 parts, sulfur, 2 ~ 5 parts, Semen Armeniacae Amarum, Semen Ginkgo 8 ~ 13 parts and Lithargyrum 1 ~ 3 part.
Further, in described internal modulation agent, the parts by weight of various composition are: the Radix Angelicae Dahuricae 4 parts, 1 part, zinc sulfate, Radix Platycodonis 5 parts and vitaminB10 part; In described BAIYAO, the parts by weight of various composition are: stearic acid 13 parts, 0.5 part, caustic potash, glycerol 5 parts, ethyl hydroxybenzoate 0.1 part, retinoic acid 6 parts and metronidazole 3 parts; In described black powder, the parts by weight of various composition are: Radix Et Rhizoma Rhei 14 parts, 5 parts, sulfur, 3.5 parts, Semen Armeniacae Amarum, Semen Ginkgo 10 parts and Lithargyrum 2 parts.
Further, described internal modulation agent is oral formulations; Described vitamin B is vitamin B6.
Further, the various compositions in described black powder are Powdered.Described BAIYAO and black powder separate external application, and this BAIYAO and black powder are and carry out external application again with water furnishing paste body shape.
A kind of application process of medicine of described Acne treatment, described application process is: 1. BAIYAO: take stearic acid, caustic potash, glycerol, tretinoin, metronidazole and ethyl hydroxybenzoate in proportion, then use water furnishing paste body shape or thick, spread on acne place outward; 2. black powder: take Radix Et Rhizoma Rhei, sulfur, Semen Armeniacae Amarum, Semen Ginkgo and Lithargyrum in proportion, and these compositions are ground to smalls, the thick or paste body shape with water furnishing, spreads on acne place outward; 3. internal modulation agent: get the Radix Angelicae Dahuricae, zinc sulfate, Radix Platycodonis and vitamin B6 in proportion; 4., in the course for the treatment of of liniment comprising BAIYAO and black powder in external application, internal modulation agent to be taken simultaneously.
Further, the number of times of described BAIYAO external application every day is 3 times; The number of times of described black powder external application every day is 1 time, and preferably, described black powder is that before sleeping every day external application is once.Described internal modulation agent is daily 1 ~ 2 time, and the Radix Angelicae Dahuricae, zinc sulfate, Radix Platycodonis and the vitamin B6 in internal modulation agent will be taken simultaneously.
The invention provides a kind of medicine and application process thereof of Acne treatment, its beneficial effect mainly had is: the curative effect of medication that interior tune of the present invention adds external application is remarkable, is not easy recurrence, and easy to use, and has cosmetic result, has market popularization value.
Detailed description of the invention
The medicine of a kind of Acne treatment described in the embodiment of the present invention and application process thereof.For specific experiment case, detailed description of the invention is described below, should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
Embodiment 1
In described internal modulation agent, the parts by weight of various composition are: 1. Radix Angelicae Dahuricae 4g, zinc sulfate 1g, Radix Platycodonis 6g and adenine phosphate g; 2. Radix Angelicae Dahuricae 3g, zinc sulfate 2g, Radix Platycodonis 4g and VB8 g; 3. Radix Angelicae Dahuricae 7g, zinc sulfate 1g, Radix Platycodonis 5g and vitaminB10 g.4. Radix Angelicae Dahuricae 2g, zinc sulfate 3g, Radix Platycodonis 1g and VB11 g; 5. Radix Angelicae Dahuricae 4g, zinc sulfate 1g, Radix Platycodonis 6g and vitamin B3 g;
As further preferred embodiment, described internal modulation agent is oral formulations; Described vitamin B is vitamin B6.
Embodiment 2
In described BAIYAO, the parts by weight of various composition are: 1. stearic acid 13g, caustic potash 0.8g, glycerol 4g, ethyl hydroxybenzoate 1g, retinoic acid 6g and metronidazole 6g; 2. stearic acid 20g, caustic potash 0.1g, glycerol 10g, ethyl hydroxybenzoate 0.1g, retinoic acid 8g and metronidazole 3g; 3. stearic acid 16g, caustic potash 0.4g, glycerol 7g, ethyl hydroxybenzoate 0.5g, retinoic acid 7g and metronidazole 4g; 4. stearic acid 13g, caustic potash 0.5g, glycerol 5g, ethyl hydroxybenzoate 0.1g, retinoic acid 6g and metronidazole 3g.
In described black powder, the parts by weight of various composition are: 1. Radix Et Rhizoma Rhei 12g, sulfur 6g, Semen Armeniacae Amarum 2g, Semen Ginkgo 13g and Lithargyrum 1g.2. Radix Et Rhizoma Rhei 16g, sulfur 3g, Semen Armeniacae Amarum 5g, Semen Ginkgo 8g and Lithargyrum 3g; 3. in described black powder, the parts by weight of various composition are: Radix Et Rhizoma Rhei 14g, sulfur 5g, Semen Armeniacae Amarum 3.5g, Semen Ginkgo 10g and Lithargyrum 2g; 4. Radix Et Rhizoma Rhei 13g, sulfur 5g, Semen Armeniacae Amarum 4g, Semen Ginkgo 12g and Lithargyrum 2.5g; 5. Radix Et Rhizoma Rhei 14 parts, 5 parts, sulfur, 3.5 parts, Semen Armeniacae Amarum, Semen Ginkgo 10 parts and Lithargyrum 2 parts.
As further preferred embodiment, described BAIYAO and black powder separate external application, and this BAIYAO and black powder are and carry out external application again with water furnishing paste body shape.
Embodiment 3
The application process of the medicine of Acne treatment is: 1. BAIYAO: take stearic acid, caustic potash, glycerol, retinoic acid, metronidazole and ethyl hydroxybenzoate in proportion, then uses water furnishing paste body shape or thick, spreads on acne place outward; 2. black powder: take Radix Et Rhizoma Rhei, sulfur, Semen Armeniacae Amarum, Semen Ginkgo and Lithargyrum in proportion, and these compositions are ground to smalls, the thick or paste body shape with water furnishing, spreads on acne place outward; 3. internal modulation agent: get the Radix Angelicae Dahuricae, zinc sulfate, Radix Platycodonis and vitamin B6 in proportion; 4., in the course for the treatment of of liniment comprising BAIYAO and black powder in external application, internal modulation agent to be taken simultaneously.
In BAIYAO in the present embodiment, black powder and internal modulation agent, the ratio of various composition is consistent with the ratio in summary of the invention and embodiment 1 and 2, is not repeating to limit here.
As further preferred embodiment, the number of times of described BAIYAO external application every day is 3 times; The number of times of described black powder external application every day is 1 time, and preferably, and black powder is that before sleeping every day external application is once.
As further preferred embodiment, described internal modulation agent is daily 1 ~ 2 time, preferred every day 1 time, and the Radix Angelicae Dahuricae, zinc sulfate, Radix Platycodonis and the vitamin B6 in internal modulation agent will be taken simultaneously.
As further preferred embodiment, the various compositions in described black powder are Powdered.
Embodiment 4
1. experimental group: interior tune+external application, namely adopts the medicine of Acne treatment of the present invention to be that patients with acne is treated: patient 331 example, wherein routine female 299 example of man 32; Year in minimum 12 years old, maximum 49 years old; 20 ~ 40 years old account for 80%.These patients are daily internal modulation agent 2 times, sooner or later respectively once; And adopt every day outside BAIYAO and spread on affected part 3 times, be respectively early, middle and late, and with spreading on affected part outside black powder 1 time before sleeping every day.
2. matched group: external application, patient 100 example, wherein routine female 89 example of man 11; Minimum 12 years old of age, maximum 51 years old, in the routine patient of person 100,12 ~ 19 years old account for 32%, 20 ~ 40 years old account for 65%.These patients are to adopt every day outside BAIYAO and spread on affected part 3 times, are respectively early, middle and late, and with spreading on affected part outside black powder 1 time before sleeping every day.
Above-mentioned two groups of patients are all without chronic disease, and the equal non-pregnancy of female patient, stadium is all in March ~ 20 year, and wherein, within more than 2 years, patient accounts for 80%.Above-mentioned two groups of patients have all treated 2 months.Result is as shown in the table.
Note: fully recover for skin lesion disappears 100%; Be almost recovered and be greater than 95% for skin lesion disappears; Effectively disappear 70 ~ 94% for skin lesion; Effectively for skin lesion disappears 40 ~ 69%; Invalid for skin lesion is unchanged or disappear and be less than 40%.
As from the foregoing, adopt the medicine of Acne treatment of the present invention, namely internal modulation agent and liniment are treated simultaneously, its curative effect highly significant, and cure rate reaches 97%, and the skin lesion extinction rate of the patient of other 3% is all between 70 ~ 94%; As long as the successful of this medicine carries out external application higher than simple liniment.
Find from the treatment of above-mentioned experimental group (interior tune adds external application) and matched group (external application), the cure rate of interior tune+external application reaches 97%, and the skin lesion extinction rate of the patient of other 3% is all between 70 ~ 94%; And matched group is only only 37% with its effective percentage of external application, the cure rate of experimental group is apparently higher than matched group.X is obtained through statistical procedures
2> 6.635, P < 0.01, namely medicine of the present invention has extremely significant effect.
The BAIYAO of external application is without any side effects, can be used as cosmetics or skin care item use.
During concrete use, if by method of the present invention use just can, particular/special requirement is not had to the interval etc. between BAIYAO, black powder and internal modulation agent.
The present invention is not limited to above-mentioned preferred forms, anyone for the present invention any modification done under enlightenment of the present invention or change, and every have identical with the application or akin technical scheme, all drops within protection scope of the present invention.
Claims (10)
1. a medicine for Acne treatment, is characterized in that: described medicine comprises internal modulation agent and liniment,
Described internal modulation agent comprises the Radix Angelicae Dahuricae, zinc sulfate, Radix Platycodonis and vitamin B;
Described liniment comprises BAIYAO and black powder, and described white the effective elements of the medicine comprises stearic acid, caustic potash, glycerol, ethyl hydroxybenzoate, retinoic acid and metronidazole; Described black the effective elements of the medicine comprises Radix Et Rhizoma Rhei, sulfur, Semen Armeniacae Amarum, Semen Ginkgo and Lithargyrum.
2. the medicine of Acne treatment according to claim 1, is characterized in that: in described internal modulation agent, the parts by weight of various composition are: the Radix Angelicae Dahuricae 2 ~ 4 parts, 1 ~ 3 part, zinc sulfate, Radix Platycodonis 1 ~ 6 part and vitamin B3 ~ 11 part; In described BAIYAO, the parts by weight of various composition are: stearic acid 13-20 part, caustic potash 0.1-0.8 part, glycerol 4 ~ 10 parts, ethyl hydroxybenzoate 0.1 ~ 1 part, retinoic acid 6 ~ 8 parts and metronidazole 3 ~ 6 parts; In described black powder, the parts by weight of various composition are: Radix Et Rhizoma Rhei 12 ~ 16 parts, 3 ~ 6 parts, sulfur, 2 ~ 5 parts, Semen Armeniacae Amarum, Semen Ginkgo 8 ~ 13 parts and Lithargyrum 1 ~ 3 part.
3. the medicine of Acne treatment according to claim 2, is characterized in that: in described internal modulation agent, the parts by weight of various composition are: the Radix Angelicae Dahuricae 4 parts, 1 part, zinc sulfate, Radix Platycodonis 5 parts and vitaminB10 part; In described BAIYAO, the parts by weight of various composition are: stearic acid 13 parts, 0.5 part, caustic potash, glycerol 5 parts, ethyl hydroxybenzoate 0.1 part, retinoic acid 6 parts and metronidazole 3 parts; In described black powder, the parts by weight of various composition are: Radix Et Rhizoma Rhei 14 parts, 5 parts, sulfur, 3.5 parts, Semen Armeniacae Amarum, Semen Ginkgo 10 parts and Lithargyrum 2 parts.
4. the medicine of the Acne treatment according to any one of claims 1 to 3, is characterized in that: described internal modulation agent is oral formulations; Described vitamin B is vitamin B6.
5. the medicine of Acne treatment according to claim 4, is characterized in that: the various compositions in described black powder are Powdered.
6. the medicine of Acne treatment according to claim 5, is characterized in that: described BAIYAO and black powder separate external application, and this BAIYAO and black powder are and carry out external application again with water furnishing paste body shape.
7. an application process for the medicine of Acne treatment according to claim 4, is characterized in that: described application process is:
1. BAIYAO: take stearic acid, caustic potash, glycerol, tretinoin, metronidazole and ethyl hydroxybenzoate in proportion, then uses water furnishing paste body shape or thick, spreads on acne place outward;
2. black powder: take Radix Et Rhizoma Rhei, sulfur, Semen Armeniacae Amarum, Semen Ginkgo and Lithargyrum in proportion, and these compositions are ground to smalls, the thick or paste body shape with water furnishing, spreads on acne place outward;
3. internal modulation agent: get the Radix Angelicae Dahuricae, zinc sulfate, Radix Platycodonis and vitamin B6 in proportion;
4., in the course for the treatment of of liniment comprising BAIYAO and black powder in external application, internal modulation agent to be taken simultaneously.
8. the application process of the medicine of Acne treatment according to claim 7, is characterized in that: the number of times of described BAIYAO external application every day is 3 times; The number of times of described black powder external application every day is 1 time.
9. the application process of the medicine of Acne treatment according to claim 7, is characterized in that: described black powder is that before sleeping every day external application is once.
10. the application process of the medicine of Acne treatment according to claim 7, is characterized in that: described internal modulation agent is daily 1 ~ 2 time, and the Radix Angelicae Dahuricae, zinc sulfate, Radix Platycodonis and the vitamin B6 in internal modulation agent will be taken simultaneously.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510556901.3A CN105055484B (en) | 2015-09-02 | 2015-09-02 | A kind of drug and its application method for treating acne |
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| CN201510556901.3A CN105055484B (en) | 2015-09-02 | 2015-09-02 | A kind of drug and its application method for treating acne |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109562082A (en) * | 2016-05-31 | 2019-04-02 | 莱雅公司 | Anti-acne compsn and application method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102451108A (en) * | 2010-10-28 | 2012-05-16 | 张兰珍 | Cream for removing acne |
| CN102552563A (en) * | 2011-11-12 | 2012-07-11 | 马海波 | Medicament for treating acne |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102451108A (en) * | 2010-10-28 | 2012-05-16 | 张兰珍 | Cream for removing acne |
| CN102552563A (en) * | 2011-11-12 | 2012-07-11 | 马海波 | Medicament for treating acne |
Non-Patent Citations (2)
| Title |
|---|
| 朱再江等主编: "《实用医学美容手册》", 31 May 1994, 贵州科技出版社 * |
| 苏冠群等编著: "《全科家庭医生》", 31 May 2006, 中国人口出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109562082A (en) * | 2016-05-31 | 2019-04-02 | 莱雅公司 | Anti-acne compsn and application method |
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