CN105054903A - Multi-parameter monitoring system - Google Patents
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- CN105054903A CN105054903A CN201510366255.4A CN201510366255A CN105054903A CN 105054903 A CN105054903 A CN 105054903A CN 201510366255 A CN201510366255 A CN 201510366255A CN 105054903 A CN105054903 A CN 105054903A
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Abstract
The invention provides a multi-parameter monitoring system. The multi-parameter monitoring system comprises a terminal device, a probe module and a blood pressure measuring module. The probe module maintains communication with the terminal device, and the probe module is at least used for obtaining intracranial pressure and transmitting the intracranial pressure to the terminal device; the blood pressure measuring module maintains communication with the terminal device, and the blood pressure measuring module is at least used for obtaining mean arterial pressure and transmitting the mean arterial pressure to the terminal device; and the terminal device calculates according to the received intracranial pressure and the received mean arterial pressure to obtain cerebral perfusion pressure, and the terminal device is at least used for displaying the cerebral perfusion pressure. The multi-parameter monitoring system can directly obtain the cerebral perfusion pressure according to the received intracranial pressure and the received mean arterial pressure, and the problem that an existing monitoring system needs to respectively measure the intracranial pressure and the mean arterial pressure, and then the cerebral perfusion pressure is calculated manually is solved.
Description
Technical field
The present invention relates to Implanted medical system field, particularly relate to a kind of multi-parameter monitoring system.
Background technology
Show clinically, when intracranial pressure ICP rises, time when cerebral perfusion pressure CPP declines to a certain extent, the imbalance of cerebrovascular autoregulation mechanism, cerebral blood flow CBF can sharply decline.When intracranial pressure ICP rises close to mean arterial pressure mSAP, intracranial blood almost stops completely, can cause irreversible cerebral ischemia, brain operation even death.
Existing monitor system needs to measure intracranial pressure ICP and mean arterial pressure mSAP respectively, manually compute cerebral perfusion pressure CPP again, the method is waste of manpower people basis not only, also cannot obtain relevant parameter in time, thus suitable treatment means cannot be applied to brain injury patients in time, likely miss best occasion for the treatment.
Summary of the invention
The object of the present invention is to provide a kind of multi-parameter monitoring system.
One of for achieving the above object, an embodiment of the present invention provides a kind of multi-parameter monitoring system, comprise terminal unit, probe module and blood pressure measurement module, probe module keeps communicating with described terminal unit, and described probe module is at least for obtaining intracranial pressure and described intracranial pressure being transferred to described terminal unit; Blood pressure measurement module and described terminal unit keep communicating, and described blood pressure measurement module is at least for obtaining mean arterial pressure and described mean arterial pressure being transferred to described terminal unit; Wherein, described terminal unit calculates cerebral perfusion pressure according to the described intracranial pressure received and described mean arterial pressure, and described terminal unit is at least for showing described cerebral perfusion pressure.
As the further improvement of an embodiment of the present invention, be radio communication between described terminal unit and described probe module and described blood pressure measurement module.
As the further improvement of an embodiment of the present invention, described probe module is also for obtaining intracranial temperature.
As the further improvement of an embodiment of the present invention, described terminal unit is also for showing described intracranial temperature, described intracranial pressure, the wherein partial parameters of described mean arterial pressure or whole parameters.
As the further improvement of an embodiment of the present invention, the numerical value that is shown as of described parameter shows or waveform display.
As the further improvement of an embodiment of the present invention, described terminal unit also comprises Tip element, and described Tip element is for judging that whether described parameter is abnormal.
As the further improvement of an embodiment of the present invention, the corresponding threshold value of parameter described in each, when described parameter improves or be reduced to corresponding described threshold value, described Tip element work.
As the further improvement of an embodiment of the present invention, described blood pressure measurement module is also for obtaining systolic pressure and diastolic pressure and described blood pressure measurement module calculates described mean arterial pressure according to described systolic pressure and diastolic pressure.
As the further improvement of an embodiment of the present invention, the corresponding multiple described probe module of terminal unit described in each and multiple described blood pressure measurement module.
As the further improvement of an embodiment of the present invention, described multi-parameter monitoring system also comprises central monitoring system, the corresponding multiple described terminal unit of central monitoring system described in each.
Compared with prior art, beneficial effect of the present invention is: monitor system of the present invention directly can obtain cerebral perfusion pressure according to the intracranial pressure received and mean arterial pressure, eliminate existing monitor system to need to measure intracranial pressure and mean arterial pressure respectively, then manually compute the drawback of cerebral perfusion pressure.
Accompanying drawing explanation
Fig. 1 is the multi-parameter monitoring system architecture diagram of an embodiment of the present invention;
Fig. 2 is the sonde configuration schematic diagram of an embodiment of the present invention;
Fig. 3 is the sonde configuration schematic diagram of other embodiments of the present invention;
Fig. 4 is the first radio unit block diagram of an embodiment of the present invention;
Fig. 5, Fig. 6 are the structured flowcharts of the multi-parameter monitoring system of other embodiments of the present invention.
Detailed description of the invention
Describe the present invention below with reference to detailed description of the invention shown in the drawings.But these embodiments do not limit the present invention, the structure that those of ordinary skill in the art makes according to these embodiments, method or conversion functionally are all included in protection scope of the present invention.
As shown in Figure 1, the multi-parameter monitoring system 100 of an embodiment of the present invention comprises probe module 10, blood pressure measurement module 20 and terminal unit 30, described terminal unit 30 keeps communicating with between described probe module 10, described blood pressure measurement module 20, and communication mode can comprise radio communication, wire communication etc.
Concrete, as shown in Figure 1, described probe module 10 comprises the first radio-cell 11, probe 12 and the first control unit 13, described blood pressure measurement module 20 comprises the second radio-cell 21, measuring unit 22, computing unit 23 and display unit 24, and described terminal unit 30 comprises the 3rd radio-cell 31, memory element 32, arithmetic element 33, processor 34 and Tip element 35.Wherein, the physiological data (data such as pressure, temperature) of the sign intracranial state got is wirelessly transmitted to the 3rd radio-cell 31 of terminal unit 30 by described probe module 10 by the first radio-cell 11, simultaneously, described blood pressure measurement module 20 by the second radio-cell 21 by One method of transmitting physiological datas such as the mean arterial pressures that gets to the 3rd radio-cell 31 of terminal unit 30, the mode of radio communication can improve the range of degree of freedom in system and coverage.The communication mode of present embodiment is not as limit, and terminal unit 30 can be connected by cable with between described probe module 10, described blood pressure measurement module 20.
As shown in Figure 2, multi-parameter monitoring system 100 is guarded for there being the intracranial of wound.Described probe module 10 comprises probe 12, and probe 12 carries out signal sensing by probe contacts 121 is put into patient's intracranial.Wherein, in the present embodiment, the implantation housing 1211 that probe contacts 121 comprises wire (sign), be arranged on described wire one end and the sensor chip 1212 be arranged on the groove 12111 of this implantation housing 1211, wherein, sensor chip 1212 is held in the mode not by mechanical stress to be implanted in housing 1211, to ensure that the sensing process of sensor chip 1212 is not subject to the interference of external device (ED) or structure.
In order to prevent intracranial tissue from entering probe contacts 121, finally the silica gel coating (not shown) sealing sensor chip 1212 to be set implanting housing 1211 place.Sensor chip 1212 is provided with sensor (sign), sensor comprises the pressure transducer that can sense intracranial pressure ICP and the temperature sensor that can sense intracranial temperature BT, and described pressure transducer, described temperature sensor and sensor chip 1211 can be one-body molded.It should be noted that, implant in housing 1211 though sensor chip 1212 is sealed in by silica gel coating, but the pressure transducer on sensor chip 1212 and temperature sensor still can sense intracranial pressure ICP and intracranial temperature BT through silica gel coating.Particularly, as shown in Figure 2, sensor setting at the upper surface of sensor chip 1212, namely towards the surface of silica gel.The setting position of sensor chip 1212 is not limited with above-mentioned, as shown in Figure 3, now, sensor chip 1212 ' is arranged around the outer surface of described groove 12111 ' on the radial circumference direction of described implantation housing 1211 ', namely now sensor chip 1212 ' is ring-band shape, and sensor spreads all over sensor chip 1212 ' setting, so, sensor can comprehensive perception intracranial pressure ICP and intracranial temperature BT.Here, it should be noted that, now groove 12111 ' is all arranged towards central concave on the radial circumference of described implantation housing 1211 ', can be arranged in groove 12111 ' completely to make ring-type sensor chip 1212 '.Described ring-type sensor chip 1212 ' have the pressure transducer comprising and can sense intracranial pressure ICP and the temperature sensor that can sense intracranial temperature BT, described pressure transducer and, described temperature sensor and sensor chip 1212 can be one-body molded or be divided into integrated temperature sensing chip and integrated pressure sensing chip, and the outer surface of described sensor chip 1212 ' is lower than the outer surface of described implantation housing 1211 ', so, avoid sensor chip 1212 ' to protrude out and insert housing 1211 surface and damage intracranial tissue, and the coating of silica gel can be facilitated.In addition, in order to prevent probe 12 from causing patient's intracranial infection, can in probe contacts 121 place coating infection material coating.
The intracranial pressure ICP sensed and intracranial temperature BT is passed to the first control unit 13 by pressure transducer and temperature sensor, and then by the first radio-cell 11, the intracranial pressure ICP got and intracranial temperature BT is wirelessly transmitted to terminal unit 30.
Concrete, as shown in Figure 4, probe 12 is after calibration, probe contacts 121 is put into the cranium brain of patient, its intracranial pressure ICP by the pressure transducer on real-time sensor chip 1212 and temperature sensor senses patient and intracranial temperature BT also converts the intracranial pressure ICP sensed and intracranial temperature BT to the signal of telecommunication, the signal of telecommunication by the input interface of transmission line to the first control unit 13, and through Matching of the interfaces circuit, outputs to the output interface of the first control unit 13 after conversion.The output interface of the first control unit 13 is connected with the first radio-cell 11 again, particularly, the output interface of the first control unit 13 is connected with the first radio-cell 11 input interface, the input interface of the first radio-cell 11 receives the signal of telecommunication after the first control unit 13 mates, and transfer to operational amplifier 111 to after its Filtering Processing, operational amplifier 111 completes and regulates the amplification of the signal of telecommunication together with feedback unit 112, makes the gain that the signal of telecommunication reaches certain; Then, A/D converter 113 carries out sampling processing to the signal of telecommunication after amplifying, and converts digital signal to; Controller 114 reads the digital signal after A/D converter 113 conversion, and obtains corresponding readable intracranial pressure ICP and intracranial temperature BT after analytical calculation; Meanwhile, controller 114 controls the first radio-cell 11 and realizes radio communication with terminal unit 30.Here terminal unit 30 can be such as monitor, smart mobile phone, PAD etc., readable intracranial pressure ICP and intracranial temperature BT is such as sent to terminal unit 30 by Bluetooth protocol or wifi agreement etc. by the first radio-cell 11, meanwhile, the instruction from terminal unit 30 or data can also be received.
Multi-parameter monitoring system 100 is simultaneously also for blood pressure monitoring.Blood pressure measurement module 20 such as can be upper arm sphygmomanometer.The measuring unit 22 of blood pressure measurement module 20 can the measurement carrying out systolic pressure SP and diastolic pressure DP of timing, the systolic pressure SP that described computing unit 23 can obtain according to measurement and diastolic pressure DP calculates mean arterial pressure mSAP, wherein, the computing formula of mean arterial pressure mSAP is: mSAP=(SP+2*DP)/3, then by the second radio-cell 21, the mean arterial pressure mSAP got is wirelessly transmitted to terminal unit 30.Here, it should be noted that, the computing formula of mean arterial pressure mSAP is not limited with above-mentioned, can determine according to practical situation.The blood pressure measurement module 20 of present embodiment also comprises display unit 24, after measuring unit 22 measurement obtains the parameters such as systolic pressure SP, diastolic pressure DP and mean arterial pressure mSAP, display unit 24 can directly show those parameters, and the blood pressure measurement module 20 of present embodiment also can separately for the monitoring of patient's blood pressure (comprising systolic pressure SP, diastolic pressure DP, mean arterial pressure mSAP etc.).In addition, the blood pressure measurement module 20 of present embodiment also can measure the Pulse-Parameters obtaining patient simultaneously.Blood pressure measurement module 20 also can be the noinvasive or invasive blood pressure signal that are measured by existing patient monitor: pulse, mean arterial pressure mSAP, systolic pressure SP and diastolic pressure DP are transferred to blood pressure measurement module 20 by Ethernet, and this data wireless is transferred to terminal unit 30 by blood pressure measurement module 20 again.
In the present embodiment, the monitoring process of probe module 10 needs to carry out in real time, and the monitoring process of blood pressure measurement module 20 can regularly carry out, such as, measure once every 15min.
In the present embodiment, after terminal unit 30 receives intracranial pressure ICP, the intracranial temperature BT of the transmission of probe module 10 and the mean arterial pressure mSAP of blood pressure measurement module 20 transmission, intracranial pressure ICP, intracranial temperature BT and mean arterial pressure mSAP are first stored in memory element 32 by terminal unit 30, arithmetic element 33 can directly calculate cerebral perfusion pressure CPP according to the intracranial pressure ICP got and mean arterial pressure mSAP, wherein, the computing formula of cerebral perfusion pressure CPP is: CPP=mSAP-ICP, then can directly show cerebral perfusion pressure CPP on terminal unit 30.Here, compared to prior art, present embodiment directly can obtain intracranial pressure ICP and mean arterial pressure mSAP simultaneously, and directly can calculate and show cerebral perfusion pressure CPP, eliminate in prior art the drawback needing to measure intracranial pressure ICP, mean arterial pressure mSAP and manual calculation cerebral perfusion pressure CPP respectively.
Here, it should be noted that, terminal unit 30 li also can comprise processor 34, each physiological data undressed can directly be transferred to terminal unit 30 by probe module 10 and blood pressure measurement module 20, processor 34 in terminal unit 30 carries out analyzing and processing to each physiological data again, so, probe module 10 and blood pressure measurement module 20 cost can be reduced, improve the versatility of probe module 10 and blood pressure measurement module 20.Concrete, such as, without the need to arranging operational amplifier 111, feedback unit 112 etc. again in probe module 10, and only need by pressure transducer and temperature sensor senses to intracranial pressure ICP and intracranial temperature BT directly transfer to terminal unit 30, the process such as the processor 34 in terminal unit 30 amplifies intracranial pressure ICP and intracranial temperature BT again, sampling, finally obtain readable intracranial pressure ICP and intracranial temperature BT; Again such as, the systolic pressure SP that measurement can directly obtain by blood pressure measurement module 20 and diastolic pressure DP transfers to terminal unit 30, the processor 34(in terminal unit 30 or arithmetic element 33) directly calculate mean arterial pressure mSAP according to systolic pressure SP and diastolic pressure DP.
Terminal unit 30 can show the parameters such as intracranial pressure ICP, intracranial temperature BT, mean arterial pressure mSAP, cerebral perfusion pressure CPP, systolic pressure SP, diastolic pressure DP and pulse simultaneously, but not as limit, terminal unit 30 selectively partly can show above-mentioned parameter according to practical situation.The display mode of terminal unit 30 such as can be numerical value display, but not as limit, in other embodiments, the waveform of the parameters in a period of time can be shown intuitively, such as intracranial pressure waveform, intracranial temperature waveform, cerebral perfusion pressure waveform etc., so, medical personnel's monitor patients dynamic trend change is more intuitively and accurately facilitated.
In another embodiment of the present invention, terminal unit 30 can real-time monitoring intracranial pressure ICP, intracranial temperature BT, and timing monitoring cerebral perfusion pressure CPP, namely now terminal unit 30 can show intracranial pressure ICP, intracranial temperature BT and cerebral perfusion pressure CPP simultaneously.
Show clinically, when intracranial pressure ICP rises, time when cerebral perfusion pressure CPP declines to a certain extent, the imbalance of cerebrovascular autoregulation mechanism, cerebral blood flow CBF can sharply decline; And when intracranial pressure ICP rises close to mean arterial pressure mSAP, intracranial blood almost stops completely, irreversible cerebral ischemia, brain operation even death can be caused.In addition, the height of intracranial temperature BT, the degree of the cell damage that also directly affects the nerves evil and scope.Therefore, present embodiment is while intracranial pressure ICP, and monitor cerebral perfusion pressure CPP and intracranial temperature BT, contributes to improving treatment, reducing mortality rate.Compared to prior art, the relevant parameter that present embodiment can show according to terminal unit 30 knows patient status in time, and applies suitable treatment means to brain injury patients in time, avoids missing best occasion for the treatment.
The Tip element 35 of terminal unit 30 of the present invention is for judging whether the parameters (comprising intracranial pressure ICP, intracranial temperature BT, mean arterial pressure mSAP, cerebral perfusion pressure CPP, systolic pressure SP, diastolic pressure DP and pulse) of guarding has exception, when judging have abnormal, described Tip element 35 works, and gives a warning.Store the threshold value of corresponding parameters in the memory element 32 of terminal unit 30, after parameters improves or is reduced to corresponding threshold value, described Tip element 35 will give a warning.In other embodiments, terminal unit 30 also can judge whether to need drain simultaneously, concrete, multi-parameter monitoring system 100 also comprises drainage tube (sign), one end of drainage tube is placed in Intraventricular, the external drainage bottle of the other end, such as when judging that intracranial pressure ICP is abnormal, terminal unit 30 can be pointed out to be needed to perform drainage procedure, now, by drainage tube by blood residual for Intraventricular, the extractions such as blood contained cerebrospinal fluid, to reduce intracranial pressure, reduce hemoglobin to the stimulation of ventricles of the brain wall, alleviate cerebral edema, simultaneously, can real-time monitored intracranial pressure ICP dynamic, prevent drain from excessively causing low intracranial pressure.
Concrete, such as, store intracranial pressure threshold value, cerebral perfusion pressure threshold value, mean arterial pressure threshold value, systolic pressure threshold value and intracranial temperature threshold in described memory element 32, after parameters improves or is reduced to corresponding threshold value, described Tip element 35 will give a warning.Again such as, when intracranial pressure ICP, mean arterial pressure mSAP, cerebral perfusion pressure CPP meet a certain condition simultaneously, described Tip element 35 gives a warning, clinical research shows: as intracranial pressure ICP>40mmHg, during cerebral perfusion pressure CPP<50mmHg, the imbalance of cerebrovascular autoregulation mechanism, cerebral blood flow CBF can sharply decline; Or when intracranial pressure ICP rises close to mean arterial pressure mSAP, intracranial blood almost stops completely, can cause irreversible cerebral ischemia, brain operation even death, now, Tip element 35 gives a warning and warns intensity suitably to strengthen.The prompting of above-mentioned corresponding different parameters can be different, such as, show the warning light of different colours, but also can be identical, and medical personnel check terminal unit 30 after can hearing prompting and be confirmed to be which parameter have exception voluntarily.
The present invention illustrate only the embodiment of one group of probe module 10, the corresponding terminal unit 30 of blood pressure measurement module 20, and wherein, one group of probe module 10, blood pressure measurement module 20 may correspond to a patient, but not as limit.As shown in Figure 5, whole monitor system 100 comprises many groups of probes module 10, blood pressure measurement modules 20 of multiple patient (patient 1 ~ patient n) and many group correspondences, and those probe modules 10, blood pressure measurement module 20 keep communicating with a terminal unit 30 simultaneously.Concrete, now terminal unit 30 can be the communication equipment of the doctor of responsible multiple patient, in practice, doctor can check measurement data by APP software, the online state of an illness understanding every patient in real time, collect the real-time change of patient parameter in each ward simultaneously, make doctor just can obtain the health of every patient at night shift room, and automatically can remind doctor when patient is critically ill.
It is worth mentioning that at this; as shown in Figure 6; multi-parameter monitoring system 100 in the present invention also comprises the central monitoring system 40 of nurse station; central monitoring system 40 provides Centralized Monitoring function; central monitoring system 40 can communicate with setting up between each terminal unit 30; Real-time Obtaining measurement data; and display measurement data; central monitoring system 40 can each parameter of automatic analysis whether normal, under exception or emergency case, trigger alarm device is so that medical personnel can take corresponding treatment measure timely and effectively.Concrete, now terminal unit 30 can be total monitor in each ward, and central monitoring system 40 can guard the situation of multiple ward patient.
Be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should by description integrally, technical scheme in each embodiment also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.
A series of detailed description listed is above only illustrating for feasibility embodiment of the present invention; they are also not used to limit the scope of the invention, all do not depart from the skill of the present invention equivalent implementations done of spirit or change all should be included within protection scope of the present invention.
Claims (10)
1. a multi-parameter monitoring system, is characterized in that comprising:
Terminal unit;
Probe module, keep communicating with described terminal unit, described probe module is at least for obtaining intracranial pressure and described intracranial pressure being transferred to described terminal unit;
Blood pressure measurement module, keeps communicating with described terminal unit, and described blood pressure measurement module is at least for obtaining mean arterial pressure and described mean arterial pressure being transferred to described terminal unit;
Wherein, described terminal unit calculates cerebral perfusion pressure according to the described intracranial pressure received and described mean arterial pressure, and described terminal unit is at least for showing described cerebral perfusion pressure.
2. multi-parameter monitoring system according to claim 1, is characterized in that, is radio communication between described terminal unit and described probe module and described blood pressure measurement module.
3. multi-parameter monitoring system according to claim 1, is characterized in that, described probe module is also for obtaining intracranial temperature.
4. multi-parameter monitoring system according to claim 3, is characterized in that, described terminal unit is also for showing described intracranial temperature, described intracranial pressure, the wherein partial parameters of described mean arterial pressure or whole parameters.
5. multi-parameter monitoring system according to claim 4, is characterized in that, the numerical value that is shown as of described parameter shows or waveform display.
6. multi-parameter monitoring system according to claim 4, is characterized in that, described terminal unit also comprises Tip element, and described Tip element is for judging that whether described parameter is abnormal.
7. multi-parameter monitoring system according to claim 6, is characterized in that, the corresponding threshold value of parameter described in each, when described parameter improves or be reduced to corresponding described threshold value, and described Tip element work.
8. multi-parameter monitoring system according to claim 1, is characterized in that, described blood pressure measurement module is also for obtaining systolic pressure and diastolic pressure, and described blood pressure measurement module calculates described mean arterial pressure according to described systolic pressure and diastolic pressure.
9. multi-parameter monitoring system according to claim 1, is characterized in that, the corresponding multiple described probe module of terminal unit described in each and multiple described blood pressure measurement module.
10. multi-parameter monitoring system according to claim 1, is characterized in that, described multi-parameter monitoring system also comprises central monitoring system, the corresponding multiple described terminal unit of central monitoring system described in each.
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CN106803011A (en) * | 2016-11-16 | 2017-06-06 | 上海浩聚医疗科技有限公司 | Neural severe monitoring method |
CN108543120A (en) * | 2018-02-05 | 2018-09-18 | 武汉大学 | A kind of encephalic cerebrospinal fluid automatic drainage device |
CN109730668A (en) * | 2018-11-30 | 2019-05-10 | 上海浩聚医疗科技有限公司 | Signal processing method based on histogram estimation brain self-regulation ability |
CN111631699A (en) * | 2020-05-18 | 2020-09-08 | 华南理工大学 | Arterial blood pressure target value range evaluation system for keeping cerebral blood flow stable |
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