CN105031108A - Medicine for treating chronic amyotrophic lateral sclerosis - Google Patents

Abstract

Medicine for treating chronic amyotrophic lateral sclerosis is prepared by, by mass, combining 15 parts of ginseng, 20 parts of rehmannia roots, 15 parts of radix achyranthis bidentatae, 20 parts of chrysanthemums, 50 parts of Chinese wax gourd peels, 50 parts of sweet potato peels, 15 parts of Chinese angelica, 15 parts of hedyotis diffusa, 50 parts of alocasia rhizomes, 15 parts of caulis spatholobi, 15 parts of dogwoods and 7 parts of liquorice. Based on the traditional Chinese medicine theory, the chronic amyotrophic lateral sclerosis is analyzed, and caused by deficiency of the liver and kidneys, deficiency of essence and blood and exogenous toxin immersion injury to tendons and muscles; according to traditional Chinese medicine treatment, the herbs of reinforcing the kidneys to replenish essence, removing heat from the liver and activating blood, and clearing and activating the channels and collaterals are combined in cooperation with alocasia rhizomes to implement the treatment scheme by the concept of combating poison with poison, in this way, a remarkable effect is certainly achieved, and a patient in despair can obtain the confidence and hope of defeating diseases.

Description

A kind of medicine for the treatment of atrophic lateral sclerosis of spinal cord

Technical field

The present invention relates to a kind of medicine for the treatment of chronic progressive external lateral sclerosis of spinal cord, particularly make the composition of medicine for the treatment of with Chinese medicine, belong to medicine technology field.

Background technology

chronicatrophic lateral sclerosis of spinal cord (Amyotrophiclateralsclerosis being called for short ALS, being commonly called as gradually freezing people's disease) is a progressive and fatal neurodegenerative diseases.Be involve upper motor neuron (brain, brain stem, spinal cord), have influence on again a kind of chronic progressive external degenerative disease of the trunk of lower motor neuron (cranial nerve nuclei, spinal cord anterior horn cell) and domination thereof, extremity and Head And Face muscle. chronicatrophic lateral sclerosis of spinal cord, Englishman also cries, and " motor neurocyte is sick, and this cannot cure and fatal disease, is a kind of motor neuron disease, is everlasting dead in 3 ~ 5 years after being ill.The prevalence of majority state ALS is 5,/10 ten thousand ~ 7,/10 ten thousand (3), and high reaches 40,/10 ten thousand, and area, Guam, the Pacific Ocean is the district occurred frequently of this disease, and China there is no statistics more accurately.Age of onset (adult type) 20 ~ 80 years old, average 57 years old, male patient was doubly to women

Often show as upper and lower motor neuron clinically and merge impaired Combination paralysis.Muscular dystrophy lateral sclerosis of spinal cord-medical history and symptom: the person in middle and old age of more than 1.40 years old are multiple, the ratio of men and women is about 3:2, slow onset, and Progressive symmetric erythrokeratodermia develops.2., with upper limb lower motor neuron paralysis, lower limb central paralysis, the symptom of the neuron indiscriminate lesion that moves up and down also saves as feature.3. bulbar paralysis symptom, Lower cranial nerves is impaired, occurs dysarthria, dysphagia, and drinking-water is choked and coughed.4. more than numbness obstacle.Health check-up finds: cranial nerve: except bulbar paralysis, can have lingualis atrophy, lingualis fibrillation, forced smile of crying by force, emotional lability etc.The common far-end of upper limb is main amyotrophy, and with large muscle of hypothenar, interosseus for work, simultaneously with fasciculation, sensation is normal.Two lower limb are spastic paralysis, hypermyotonia, tendon hyperreflexia, and bilateral pathologic reflex is positive.Respiratory muscle is got involved, and occurs dyspnea. chronicatrophic lateral sclerosis of spinal cord is easy to differentiate to cause difficulty, mistaken diagnosis with cervical spondylosis, neck section tumor of spinal cord tumor, spinal arachnoiditis etc.

chronicatrophic lateral sclerosis of spinal cord, at present without specific short, mainly treats the table disease occurred based on correspondence.One, dyspnea person, oxygen uptake, if desired assisted respiartion.Two, dysphagia person's nasal feeding or intravenous hyperalimentation, maintains nutrition and water-electrolyte balance.Three, neurotrophy medicine: citicoline 250-500mg, flesh is raw penetrates liquid 4ml, adenosine triphosphate 20-40mg, basic fibroblast growth factor (bFGF) 1600u, intramuscular injection 1-2 time/d, peaceful (Sodium Cytidine Triphosphate) 20mg intramuscular injection of U.S. network, 1 time/d.Four, trihexyphenidyl 2mg3 time/d or wonderful sodium 50-100mg/d is oral alleviates or improves upper motor neuron and damage the muscle spasm caused, hypermyotonia.Five, prevention and treatment of complication, prevents ankylosis contracture from adhering to suitable physical training and physical therapy.Prevent pulmonary infection.

Summary of the invention

chronicatrophic lateral sclerosis of spinal cord is the fatal serious disease of a kind of progressive infringement, and the cause of disease has heritability, has viral infection, has the impaired property of self immune system function.With tcm theory analysis chronicatrophic lateral sclerosis of spinal cord, belongs to caused by liver and kidney deficiency, asthenia of essence and blood, the evil poison of diseases caused by exogenous pathogenic factor, invades damage grain, Chinese traditional treatment is invigorated blood circulation with kidney tonifying, essence replenishing, liver heat removing, treating the poisonous disease with poisonous drugs, and the Chinese Medicine and Clavicular of dredge the meridian passage takes the scheme for the treatment of, and must receive curative effect.

According to upper tcm theory analysis with treat scheme, a kind of medicine for the treatment of atrophic lateral sclerosis of spinal cord taked technical scheme of dealing with problems combines by each Chinese medicine quality part ratio below: Radix Ginseng 15 parts, 20 parts, the Radix Rehmanniae, Radix Achyranthis Bidentatae 15 parts, Flos Chrysanthemi 20 parts, Exocarpium Benincasae 50 parts, Ipomoea batatas Lam. skin 50 parts, Radix Angelicae Sinensis 15 parts, Herba Hedyotidis Diffusae 15 parts, guangdong chamaejasme 50 parts, Caulis Spatholobi 15 parts, Fructus Corni 15 parts, 7 parts, Radix Glycyrrhizae.

Below by a kind of property of medicine effect for the treatment of each Chinese medicine in the medicine of atrophic lateral sclerosis of spinal cord of analysis.Radix Ginseng has effect of heart tonifying, significant effect is had to deep pulse, general weakness person, hyposthenia person, there is effect of " coming back to life ", the emergence being in shock or comatose state can be made, be the good medicine saving pulse collapse, the patient that falls into a coma, Radix Ginseng has specially good effect to the immunity strengthening people.Radix Rehmanniae heat clearing away, removing heat from blood, promote the production of body fluid, blood circulation promoting and blood stasis dispelling.Radix Achyranthis Bidentatae has kidney tonifying, essence replenishing, subduing inflammation, analgesic efficacy.Chrysanthemumization has effect of loose wind heat clearing away, liver heat removing and eyesight improving, be used for the treatment of anemopyretic cold, have a headache dizzy, conjunctival congestion and swelling pain, eyes are dim-sighted.Exocarpium Benincasae has heat clearing away, liver heat removing is invigorated blood circulation, subside a swelling reduce phlegm, effect of antiviral.Ipomoea batatas Lam. skin has heat clearing and blood circulation promoting, dissipating blood stasisization to tie, effect of suppression, kill virus.Facts have proved: patient is cured the disease and eats a large amount of Ipomoea batatas Lam. therebetween, the time of recovering can shorten by the earth, and edible Ipomoea batatas Lam. bark effect is obvious especially.Chinese angelica blood supplementing and blood, menstruction regulating and pain relieving, moisturizes laxation.Control menoxenia, amenorrhea is suffered from abdominal pain, and lump in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; Dryness of the intestine dyschezia is heavy after bloody dysentery; Carbuncle skin ulcer is stolen, injury from falling down.Effect of Agkistrodon house grass: heat-clearing and toxic substances removing, diuresis of blood circulation promoting.Herba Hedyotidis Diffusae is used for tonsillitis, pharyngolaryngitis, urinary tract infection, pelvic inflammatory disease, appendicitis, hepatitis, bacillary dysentery, venom, tumor.Guangdong chamaejasme is the rhizome position of Araeceae Rhizoma alcasiae odorae, very toxic, and contact skin can cause skin numbness red and swollen, and stem slag of by mistake eating can cause poisoning, should gastric lavage as early as possible, but the decoction soup of guangdong chamaejasme can be taken, and antiviral, function of killing the virus have specially good effect.Caulis Spatholobi: relaxing muscles and tendons to promote blood circulation; Nourishing blood for regulating menstruation.The main numb hand and foot of Caulis Spatholobi; Quadriplegia; Rheumatic arthralgia; Women has through uncomfortable; Dysmenorrhea; Amenorrhea.Caulis Spatholobi is enriched blood, and invigorates blood circulation, dredging collateral, for menoxenia, and blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.Fructus Corni liver and kidney tonifying, restrains astringent or styptic treatment for spontaneous sweating, and controlling nocturnal emission with astringent drugs reducing urination leukorrhagia stopping only collapses, hidroschesis, also has promoting the production of body fluid to quench thirst in addition.For soreness of waist and knee joint, dizziness and tinnitus, forgetful emission and spermatorrhea, urinate frequently, bleeding not during menses menoxenia, profuse sweating is collapsed.Effect of Radix Glycyrrhizae QI invigorating strengthening the spleen and middle emergency, coordinating the actions of various ingredients in a prescription.

A kind of beneficial effect for the treatment of the drug invention of atrophic lateral sclerosis of spinal cord is: inventor is with tcm theory analysis chronicatrophic lateral sclerosis of spinal cord, belong to caused by liver and kidney deficiency, asthenia of essence and blood, the evil poison of diseases caused by exogenous pathogenic factor, invade damage grain, Chinese traditional treatment invigorated blood circulation with kidney tonifying, essence replenishing, liver heat removing, the Chinese Medicine and Clavicular of dredge the meridian passage, and with guangdong chamaejasme coordinate treating the poisonous disease with poisonous drugs treat scheme, obvious curative effect must be received, the confidence and hope that patient are obtained in despair defeat the serious illness.

Detailed description of the invention

A kind of medicine for the treatment of atrophic lateral sclerosis of spinal cord combines by each Chinese medicine quality part ratio below: Radix Ginseng 15 parts, 20 parts, the Radix Rehmanniae, Radix Achyranthis Bidentatae 15 parts, Flos Chrysanthemi 20 parts, Exocarpium Benincasae 50 parts, Ipomoea batatas Lam. skin 50 parts, Radix Angelicae Sinensis 15 parts, Herba Hedyotidis Diffusae 15 parts, guangdong chamaejasme 50 parts, Caulis Spatholobi 15 parts, Fructus Corni 15 parts, 7 parts, Radix Glycyrrhizae.

From above-mentioned a kind of deal ratio for the treatment of each Chinese medicine the medicine of atrophic lateral sclerosis of spinal cord, the dose drug amount that the patient that a kind of medicine for the treatment of atrophic lateral sclerosis of spinal cord is suitable for an atrophic lateral sclerosis of spinal cord takes combines by each Chinese medicine quality below: Radix Ginseng 15 grams, 20 grams, the Radix Rehmanniae, Radix Achyranthis Bidentatae 15 grams, Flos Chrysanthemi 20 grams, Exocarpium Benincasae 50 grams, Ipomoea batatas Lam. skin 50 grams, Radix Angelicae Sinensis 15 grams, Herba Hedyotidis Diffusae 15 grams, guangdong chamaejasme 50 grams, Caulis Spatholobi 15 grams, Fructus Corni 15 grams, 7 grams, Radix Glycyrrhizae.An above-mentioned dose drug instructions of taking: decoct soup with proper amount of clear water and take soup orally, natural gift three times take.Therapeutic Method: take a dosage day, serveing on 15 days is a course for the treatment of, slightly can subtract dose after the course for the treatment of according to the state of an illness.Treatment time: 3 ~ 12 months.A kind of medicine patient treating atrophic lateral sclerosis of spinal cord takes a dosage can be effective, takes the effect that 3 days could be improved or suppress symptom, should continue to take, to promote effect.

Claims (1)

1. treat a medicine for atrophic lateral sclerosis of spinal cord, it is characterized in that combining by each Chinese medicine quality part ratio below: Radix Ginseng 15 parts, 20 parts, the Radix Rehmanniae, Radix Achyranthis Bidentatae 15 parts, Flos Chrysanthemi 20 parts, Exocarpium Benincasae 50 parts, Ipomoea batatas Lam. skin 50 parts, Radix Angelicae Sinensis 15 parts, Herba Hedyotidis Diffusae 15 parts, guangdong chamaejasme 50 parts, Caulis Spatholobi 15 parts, Fructus Corni 15 parts, 7 parts, Radix Glycyrrhizae.