CN105030706A - Method for preparing nutrition buccal tablet from Naqu cordyceps sinensis - Google Patents
Method for preparing nutrition buccal tablet from Naqu cordyceps sinensis Download PDFInfo
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- CN105030706A CN105030706A CN201510397810.XA CN201510397810A CN105030706A CN 105030706 A CN105030706 A CN 105030706A CN 201510397810 A CN201510397810 A CN 201510397810A CN 105030706 A CN105030706 A CN 105030706A
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- buccal tablet
- cordyceps
- nutrition
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- nagqu cordyceps
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Abstract
The invention discloses a method for preparing a nutrition buccal tablet from Naqu cordyceps sinensis. The method comprises A.1, raw material screening, A.2, cleaning, A.3, drying, A.4 crushing, A.5, mixing: mixing the crushed larva part and stroma micro-powder according to a ratio of 6.5: 3.5, A.6, homogenization: carrying out homogenization on the mixed powder obtained by the step A.5 and preparing a homogeneous solution with particle sizes of 400nm or less, A.7, filling a bubble cap of a bubble cap plate with the homogeneous Naqu cordyceps sinensis, A.8, carrying out freezing vacuum drying on the bubble cap plate with the homogeneous Naqu cordyceps sinensis to obtain the nutrition buccal tablet, and A.9, carrying out seal packaging on the bubble cap subjected to freezing vacuum drying. The nutrition buccal tablet retains the original unique favor of Naqu cordyceps sinensis, can retain nutritional ingredients for a long time, and is conducive to effective absorption. The method can effectively utilize a nutrition value of Naqu cordyceps sinensis.
Description
Technical field
The present invention relates to and relate to biomedicine technical field, specifically, is a kind of method utilizing Nagqu Cordyceps to prepare nutrition buccal tablet.
Background technology
Cordyceps is a kind of entomogenous fungi, parasitize the larva of Lepidoptera Lepidoptera hepialidae Hepialidae hook Genus Hepialus Thitarodes insecticide, its phorozoon is China pilose spore HirsutellasinensisLiu, Guo, Yu & Zeng.A generation of host of Cordyceps sinensis hook Genus Hepialus Thitarodes insecticide comprises ovum, larva, pupa and four stages of development of adult, tunnel type troglodytism under larva campsite, omnivorousness, the tender rhizome of children of the psychrophytes such as eating motion eccentric, Herba Polygoni Capitati, Radix et Rhizoma Rhei and Polygonum viviparum L..
Cordyceps is distributed in Qinghai-Tibet High aititude region, and this region severe cold region, its temperature has the feature of high mountain low temperature throughout the year.
Cordyceps has another name called Cordyceps, and be the famous and precious tonic herb of China's usual one among the people, its nutritional labeling, higher than Radix Ginseng, can be used as medicine, also edible, is superior delicacies, has very high nutritive value, is especially wherein with Nagqu Cordyceps.Cordyceps can the immunity of enhancing body, and nourishing lung and kidney, has obvious inhibitory action to pulmonary carcinoma, hepatocarcinoma etc.Clinically to chronic cough of deficiency lung, asthma, hemoptysis of pulmonary tuberculosis, night sweat, soreness of waist and knee joint of suffering from a deficiency of the kidney, impotence and seminal emission, the red blood cell decreased after neurasthenia and chemotherapy, radiotherapy is all effective in cure.
Summary of the invention
The object of the present invention is to provide a kind of method utilizing Nagqu Cordyceps to prepare nutrition buccal tablet, produce a kind of can the local flavor of the original uniqueness of maintenance Nagqu Cordyceps to a certain degree, also nutritional labeling can be accomplished to save from damage for a long time and be beneficial to the nutrition buccal tablet effectively absorbed, effectively can utilize the nutritive value of Nagqu Cordyceps.
The present invention is achieved through the following technical solutions: a kind of method utilizing Nagqu Cordyceps to prepare nutrition buccal tablet, comprises the following steps:
A.1 raw material selection: by all Nagqu Cordyceps raw material through fine selection, the medical material after having selected is placed in container and weighs;
A.2 clean: by weighted Nagqu Cordyceps, put in service sink, use purified water cleaning, keep wire flow velocity with the purified water lower than 15 DEG C, put into screen cloth pallet after scrubbing cleaning and drain away the water;
A.3 dry: be respectively charged in basin by the Nagqu Cordyceps cleaned up by polypide and Stroma, thickness is 3.5-4.5cm, and baking temperature controls below 55 DEG C;
A.4 pulverize: polypide and the Stroma of getting steps A .3 gained, by Stroma, polypide micronization respectively, reach the following granularity requirements of 100 order; Micropowder after pulverizing is respectively charged in clean plastic bag, weighs;
A.5 mix: get polypide and Stroma micropowder after pulverizing, mix in 6.5:3.5 ratio;
A.6 homogenizing: steps A .5 gained mixed powder is carried out homogenizing, puts into homogenizer by mixed powder and appropriate purified water, makes the homogeneous solution that granular size is below 400nm;
A.7, the Nagqu Cordyceps after homogenizing is packed in the bubble-cap of bubble cap tray;
A.8, the bubble cap tray that the Nagqu Cordyceps after homogenizing is housed is carried out lyophilisation and obtain buccal tablet; Before vacuum lyophilization, first carry out quick pre-freeze with liquid nitrogen; Then the material after quick pre-freeze is put into vacuum freeze drier and carry out vacuum lyophilization; Vacuum lyophilization is divided into vacuum drawn stage and drying stage, and the vacuum drawn stage, for will solidify shape material evacuation 3 ~ 5 hours, controls cryogenic temperature less than-40 DEG C, controls vacuum pressure: < 40Pa; When drying stage is for utilizing gradient method to make dry materials 5 ~ 8 by 0.5 ~ 1.5 DEG C of cascade raising temperature heating per hour;
A.9, the bubble-cap after lyophilisation is encapsulated.
To better implement the present invention, further, when carrying out described steps A .2, microexamination during cleaning, is utilized to test attachment suspended impurity.
Further, to better implement the present invention, the temperature of the drying described in steps A .3 is 45 DEG C.
To better implement the present invention, further, when carrying out described steps A .3, after dried Stroma and polypide cooling, will load in clean plastic bag, and seal mouth, weighing.
To better implement the present invention, further, in described steps A .6 Nagqu Cordyceps homogenizing to below 100nm.
Compared with prior art, the present invention has following beneficial effect:
The present invention produce a kind of can the local flavor of the original uniqueness of maintenance Nagqu Cordyceps to a certain degree, nutritional labeling also can be accomplished to save from damage for a long time and be beneficial to the nutrition buccal tablet effectively absorbed, effectively can utilize the nutritive value of Nagqu Cordyceps.
Nagqu Cordyceps nutrition buccal tablet prepared by the present invention, saving from damage of effective ingredient is comparatively outstanding, by the new paragon of buccal rapid in mouth, mucosa absorption, guarantee that essential ingredient release maximizes with absorbing, give full play to the dual care effect to oral cavity, throat, esophagus, gastrointestinal tract mucous and whole body.
Nagqu Cordyceps nutrition buccal tablet prepared by the present invention reaches the requirements such as instant, delicious food, safety, nourishing, and being especially suitable for and being difficult to well swallow crowd that is edible and that absorb for general food, is the product that well supplement the nutrients.
Nagqu Cordyceps nutrition buccal tablet prepared by the present invention can dissolve dispersion rapidly in oral cavity, and flavour is good to eat, and texture is soft glutinous, and chews the colloid lubrication sense of stew in addition, is greatly better than product prepared by additive method.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described, and embodiments of the present invention include but not limited to the following example.
Embodiment 1:
Utilize Nagqu Cordyceps to prepare a method for nutrition buccal tablet, comprise the following steps:
A.1 raw material selection: by all Nagqu Cordyceps raw material through fine selection, the medical material after having selected is placed in container and weighs;
A.2 clean: by weighted Nagqu Cordyceps, put in service sink, use purified water cleaning, keep wire flow velocity with the purified water lower than 15 DEG C, put into screen cloth pallet after scrubbing cleaning and drain away the water;
A.3 dry: be respectively charged in basin by the Nagqu Cordyceps cleaned up by polypide and Stroma, thickness is 3.5-4.5cm, and baking temperature controls below 55 DEG C;
A.4 pulverize: polypide and the Stroma of getting steps A .3 gained, by Stroma, polypide micronization respectively, reach the following granularity requirements of 100 order; Micropowder after pulverizing is respectively charged in clean plastic bag, weighs;
A.5 mix: get polypide and Stroma micropowder after pulverizing, mix in 6.5:3.5 ratio;
A.6 homogenizing: steps A .5 gained mixed powder is carried out homogenizing, puts into homogenizer by mixed powder and appropriate purified water, makes the homogeneous solution that granular size is below 400nm;
A.7, the Nagqu Cordyceps after homogenizing is packed in the bubble-cap of bubble cap tray;
A.8, the bubble cap tray that the Nagqu Cordyceps after homogenizing is housed is carried out lyophilisation and obtain buccal tablet; Before vacuum lyophilization, first carry out quick pre-freeze with liquid nitrogen; Then the material after quick pre-freeze is put into vacuum freeze drier and carry out vacuum lyophilization; Vacuum lyophilization is divided into vacuum drawn stage and drying stage, and the vacuum drawn stage, for will solidify shape material evacuation 3 ~ 5 hours, controls cryogenic temperature less than-40 DEG C, controls vacuum pressure: < 40Pa; When drying stage is for utilizing gradient method to make dry materials 5 ~ 8 by 0.5 ~ 1.5 DEG C of cascade raising temperature heating per hour;
A.9, the bubble-cap after lyophilisation is encapsulated.
Embodiment 2:
The present embodiment is at the enterprising one-step optimization in the basis of above-described embodiment, to better implement the present invention, further, when carrying out described steps A .2, utilizes microexamination to test attachment suspended impurity during cleaning.
Embodiment 3:
The present embodiment is at the enterprising one-step optimization in the basis of above-mentioned any embodiment, and further, to better implement the present invention, the temperature of the drying described in steps A .3 is 45 DEG C.
Embodiment 4:
The present embodiment is at the enterprising one-step optimization in the basis of above-mentioned any embodiment, to better implement the present invention, further, when carrying out described steps A .3, after dried Stroma and polypide cooling, will load in clean plastic bag, and seal mouth, weighing.
Embodiment 5:
The present embodiment is at the enterprising one-step optimization in the basis of above-mentioned any embodiment, to better implement the present invention, further, in described steps A .6 Nagqu Cordyceps homogenizing to below 100nm.
The above is only preferred embodiment of the present invention, and not do any pro forma restriction to the present invention, every any simple modification, equivalent variations done above embodiment according to technical spirit of the present invention, all falls within protection scope of the present invention.
Claims (7)
1. utilize Nagqu Cordyceps to prepare a method for nutrition buccal tablet, it is characterized in that: comprise the following steps:
A.1 raw material selection: by all Nagqu Cordyceps raw material through fine selection, the medical material after having selected is placed in container and weighs;
A.2 clean: by weighted Nagqu Cordyceps, put in service sink, use purified water cleaning, keep wire flow velocity with the purified water lower than 15 DEG C, put into screen cloth pallet after scrubbing cleaning and drain away the water;
A.3 dry: be respectively charged in basin by the Nagqu Cordyceps cleaned up by polypide and Stroma, thickness is 3.5-4.5cm, and baking temperature controls below 55 DEG C;
A.4 pulverize: polypide and the Stroma of getting steps A .3 gained, by Stroma, polypide micronization respectively, reach the following granularity requirements of 100 order; Micropowder after pulverizing is respectively charged in clean plastic bag, weighs;
A.5 mix: get polypide and Stroma micropowder after pulverizing, mix in 6.5:3.5 ratio;
A.6 homogenizing: steps A .5 gained mixed powder is carried out homogenizing, puts into homogenizer by mixed powder and appropriate purified water, makes the homogeneous solution that granular size is below 400nm;
A.7, the Nagqu Cordyceps after homogenizing is packed in the bubble-cap of bubble cap tray;
A.8, the bubble cap tray that the Nagqu Cordyceps after homogenizing is housed is carried out lyophilisation and obtain buccal tablet; Before vacuum lyophilization, first carry out quick pre-freeze with liquid nitrogen; Then the material after quick pre-freeze is put into vacuum freeze drier and carry out vacuum lyophilization; Vacuum lyophilization is divided into vacuum drawn stage and drying stage, and the vacuum drawn stage, for will solidify shape material evacuation 3 ~ 5 hours, controls cryogenic temperature less than-40 DEG C, controls vacuum pressure: < 40Pa; When drying stage is for utilizing gradient method to make dry materials 5 ~ 8 by 0.5 ~ 1.5 DEG C of cascade raising temperature heating per hour;
A.9, the bubble-cap after lyophilisation is encapsulated.
2. a kind of method utilizing Nagqu Cordyceps to prepare nutrition buccal tablet according to claim 1, is characterized in that: when carrying out described steps A .2, utilizes microexamination to test attachment suspended impurity during cleaning.
3. a kind of method utilizing Nagqu Cordyceps to prepare nutrition buccal tablet according to claim 1 and 2, is characterized in that: the temperature of the drying described in steps A .3 is 45 DEG C.
4. a kind of method utilizing Nagqu Cordyceps to prepare nutrition buccal tablet according to claim 3, is characterized in that: when carrying out described steps A .3, after dried Stroma and polypide cool, will load in clean plastic bag, and seals mouth, weigh.
5. a kind of method utilizing Nagqu Cordyceps to prepare nutrition buccal tablet according to claim 3, is characterized in that: in described steps A .6 Nagqu Cordyceps homogenizing to below 100nm.
6. a kind of method utilizing Nagqu Cordyceps to prepare nutrition buccal tablet according to claim 1 or 2 or 5, it is characterized in that: when carrying out described steps A .3, after dried Stroma and polypide cool, will load in clean plastic bag, and seal mouth, weigh.
7. a kind of method utilizing Nagqu Cordyceps to prepare nutrition buccal tablet according to claim 1 or 2 or 4, is characterized in that: in described steps A .6 Nagqu Cordyceps homogenizing to below 80nm.
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| CN101332212A (en) * | 2007-09-30 | 2008-12-31 | 张雪峰 | Aweto micropowder tablet and preparation method thereof |
| CN101537022A (en) * | 2008-03-17 | 2009-09-23 | 张雪峰 | Cordyceps sinensis shaping and drying method |
| KR20090108877A (en) * | 2008-04-14 | 2009-10-19 | 왕팔만 | A freeze drying method for vegetable worms |
| CN102742838A (en) * | 2011-07-11 | 2012-10-24 | 张雪峰 | Preparation method of Chinese caterpillar fungus freeze-dried buccal tablet |
| CN103040877A (en) * | 2012-11-30 | 2013-04-17 | 陈玉龙 | Preparation method of cordyceps sinensis micropowder lozenges |
| CN103301165A (en) * | 2013-06-21 | 2013-09-18 | 四川逢春制药有限公司 | Grinding method and application of cordyceps sinensis |
| CN103417582A (en) * | 2013-07-29 | 2013-12-04 | 曹静 | Cordyceps sinensis pure powder tablet and preparation method thereof |
| CN103652846A (en) * | 2012-09-25 | 2014-03-26 | 江苏学府生物工程有限公司 | Production method for cordyceps militaris buccal tablets |
| CN103652923A (en) * | 2013-12-11 | 2014-03-26 | 黄秀英 | Preparation method of cordyceps sinensis lozenge |
| CN104739892A (en) * | 2013-12-28 | 2015-07-01 | 大连美乐生物技术开发有限公司 | Cordyceps sinensis buccal tablet and preparation method thereof |
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2015
- 2015-07-08 CN CN201510397810.XA patent/CN105030706A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101332212A (en) * | 2007-09-30 | 2008-12-31 | 张雪峰 | Aweto micropowder tablet and preparation method thereof |
| CN101537022A (en) * | 2008-03-17 | 2009-09-23 | 张雪峰 | Cordyceps sinensis shaping and drying method |
| KR20090108877A (en) * | 2008-04-14 | 2009-10-19 | 왕팔만 | A freeze drying method for vegetable worms |
| CN102742838A (en) * | 2011-07-11 | 2012-10-24 | 张雪峰 | Preparation method of Chinese caterpillar fungus freeze-dried buccal tablet |
| CN103652846A (en) * | 2012-09-25 | 2014-03-26 | 江苏学府生物工程有限公司 | Production method for cordyceps militaris buccal tablets |
| CN103040877A (en) * | 2012-11-30 | 2013-04-17 | 陈玉龙 | Preparation method of cordyceps sinensis micropowder lozenges |
| CN103301165A (en) * | 2013-06-21 | 2013-09-18 | 四川逢春制药有限公司 | Grinding method and application of cordyceps sinensis |
| CN103417582A (en) * | 2013-07-29 | 2013-12-04 | 曹静 | Cordyceps sinensis pure powder tablet and preparation method thereof |
| CN103652923A (en) * | 2013-12-11 | 2014-03-26 | 黄秀英 | Preparation method of cordyceps sinensis lozenge |
| CN104739892A (en) * | 2013-12-28 | 2015-07-01 | 大连美乐生物技术开发有限公司 | Cordyceps sinensis buccal tablet and preparation method thereof |
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Application publication date: 20151111 Assignee: SICHAUN DICHEN AGRICULTURAL LIMITED LIABILITY COMPANY Assignor: Yi Chuansi bio tech ltd, Chengdu Contract record no.: 2016510000008 Denomination of invention: Method for preparing nutrition buccal tablet from Naqu cordyceps sinensis License type: Common License Record date: 20160506 |
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Application publication date: 20151111 |