CN105028434B - Bactericidal composition containing tetramycin and difenoconazole - Google Patents
Bactericidal composition containing tetramycin and difenoconazole Download PDFInfo
- Publication number
- CN105028434B CN105028434B CN201510359591.6A CN201510359591A CN105028434B CN 105028434 B CN105028434 B CN 105028434B CN 201510359591 A CN201510359591 A CN 201510359591A CN 105028434 B CN105028434 B CN 105028434B
- Authority
- CN
- China
- Prior art keywords
- difenoconazole
- tetramycin
- bactericidal composition
- composition containing
- oil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The weight part ratio of the invention discloses a kind of bactericidal composition containing tetramycin and difenoconazole, including insecticides adjuvant, tetramycin and difenoconazole, tetramycin and difenoconazole is 1:1~1:80, the weight percent of tetramycin and difenoconazole weight summation in the composition is 1%~80%；Tetramycin and with difenoconazole compound after have apparent synergistic function to pathogen fungi, be suitable for prevention the fungus-caused crop disease of pathogen, the especially microbial rice sheath blight disease of miliary damping-off.
Description
Technical field
Bactericidal composition of the present invention, be using tetramycin and difenoconazole as active ingredient, be suitable for prevention by
The fungus-caused crop disease of pathogen, especially Rhizoctonia solani Kuhn (Thanatephorus cucumeris) pathogen causes
Rice sheath blight disease.
Background technology
Tetramycin is by S. ahygroscopicus Wuzhou subspecies (Streptomyces ahygroscopicus
Subsp.Wuzhouensis n.subsp) biological pesticide produced by strain liquid submerged fermentation, pass through the life for inhibiting mycelia
It is long, the resistance of crop is induced, and promote plant growth and reach prevention purpose, is applicable in a variety of fungies of various forests, bacteriosis
Prevention.
Difenoconazole is a kind of absorbability triazole bactericidal agent, inhibits the synthesis of germ ergosterol, hinders germ thin
The chitinase activity of crop can be improved in the formation of cell wall, leads to the contraction of fungi haustorium, inhibits germ intrusion.
Rice sheath blight disease is also known as moire disease, and popular name spends sufficient stalk, rotten foot pest, features spot.It is by Rhizoctonia solani Kuhn
(Thanatephorus cucumeris) infection is fallen ill, and is mostly occurred under high temperature, super-humid conditions.Banded sclerotial blight is in South Rice Region of China
Evil is serious, is one of the Major Diseases in current Rice Production.The disease prevents rice from earing, or the not plump paddy of heading is more, grain
Decline again, seriously affects Rice Production.
It is found by experiment that, tetramycin combines Rhizoctonia solani (Thanatephorus with difenoconazole
Cucumeris) there is synergistic function, can be with excipient by certain technological means tetramycin and difenoconazole composition
Agriculturally common dosage form.
Invention content
The present invention is intended to provide a kind of active ingredient is the Synergistic bactericidal composition of tetramycin and difenoconazole, it is vertical withered
Crop disease caused by rhizoctonia (Thanatephorus cucumeris) especially provides for rice sheath blight disease a kind of effective
Management tool.
The invention is realized by the following technical scheme：A kind of bactericidal composition containing tetramycin and difenoconazole, has
Ingredient is imitated as tetramycin and difenoconazole, the weight part ratio of tetramycin and difenoconazole is 1:1~1:80；Tetramycin and
The weight percent of difenoconazole weight summation in the composition is 1%~80%, remaining is insecticides adjuvant.
According to the actual application, bactericidal composition of the present invention can be prepared according to well known to a person skilled in the art methods
As suspending agent, microemulsion.
The suspending agent dosage form weight percent group becomes：Tetramycin 0.01~10%, difenoconazole 1~80%,
Dispersant 0.1~18%, wetting agent 0.1~12%, antifoaming agent 0.1~3%, thickener 0.1~3%, antifreezing agent 0.1~5%,
Liquid-carrier complements to 100%.Specifically production stage is：Active ingredient and other auxiliary agents are mixed, through high speed shear dispersion, sand
After being sanded in grinding machine, high dispersive, the suspension system of stabilization are formed in water-medium, and the suspension of corresponding weight percentage is made
Agent.
The micro-emulsion form weight percent group becomes：Tetramycin 0.01~10%, difenoconazole 1~80%,
Solvent 0.1~14%, emulsifier 0.1~12%, liquid-carrier complements to 100%.Specifically production stage is：Active ingredient is molten
Solution, is added remaining auxiliary agent, and the microemulsion of corresponding weight percentage is made in stirring and dissolving.
The antifoaming agent can be one or more of silicone compound, epoxidized soybean oil, methanol, silicone oil etc..
The antifreezing agent can be one or more of in glycerine, propylene glycol, diethylene glycol (DEG), urea etc..
The wetting agent can be lauryl sodium sulfate, neopelex, sodium butylnaphthalenesulfonate, alkyl sulphur
One or more of sour sodium, tea seed cake powder, spaonin powder, spaonin powder etc..
The dispersant can be APES formaldehyde condensation product, naphthalenesulfonate formaldehyde condensation compound, to first
Oxygroup fatty acyl anilinesulfonic acid, lignosulfonates, polycarboxylate, alkyl phenol polyoxyethylene ether sulfate, alkyl benzene sulphonate
Calcium salt, aliphatic ester sulfate, alkyl phenol polyoxyethylene ether, fatty alcohol polyoxyethylene ether, polyethylene glycol stearate, sorbose
One or more of alcohol oleate, nekal etc..
The thickener can be polyvinyl acetate, xanthans, gelatin, gum arabic, aluminium-magnesium silicate, phenolic aldehyde tree
One or more of fat, hydroxymethyl cellulose, sodium alginate etc..
The liquid-carrier can be deionized water, exquisite soybean oil, corn oil, rapeseed oil, turpentine oil, oleic acid first
One or more of ester, coconut oil, palm oil, safflower oil, sesame oil, castor oil, tung oil, olive oil etc. and the above plant
The ester of oil, especially methyl esters.
The solvent can with 2-methyl cellosolve, chloroform, 1,1,2- trichloro ethylene, 1,2- dimethoxy-ethanes, 1,
2,3,4- tetrahydronaphthalenes, cellosolvo, sulfolane, pyrimidine, formamide, n-hexane, chlorobenzene, dioxane, second
Nitrile, dichloromethane, ethylene glycol, n,N-Dimethylformamide, toluene, n,N-dimethylacetamide, hexahydrotoluene,
1,2-dichloroethene, dimethylbenzene, methanol, hexamethylene, N-Methyl pyrrolidone, pentane, formic acid, acetic acid, ether, acetone, benzene
Methyl ether, methyl oleate, fatty acid methyl ester, loose base oil, soybean oil, biodiesel, ethyl alcohol, normal propyl alcohol, isopropanol, propylene glycol, third
One or more of triol, n-butanol, isooctanol, sec-Butyl Acetate, dimethyl carbonate, diesel oil, white oil, machine oil, RPDE etc..
The bactericidal composition of the present invention, for preventing rice sheath blight disease.
The bactericidal composition of the present invention, generally use spray method use, and can also use and agriculturally apply as needed
Other use technology.
Bactericidal composition provided by the invention has the advantages that：
1, bactericidal composition provided by the invention shows apparent synergy or summation action within a certain ratio range,
Composition is significantly improved to the control effect of germ than single dose, reduces the dosage of pesticide, reduces times for spraying,
Drug cost is reduced, adverse effect of the pesticide to ecological environment is reduced.
2, bactericidal composition provided by the invention, the combination of two kinds of active ingredient expand fungicidal spectrum, a drug
It solves the problems, such as multiple diseases, compensates for defect and limitation when single dose uses.
3, bactericidal composition provided by the invention, two kinds of active ingredient mechanism of action are not quite identical, can overcome long-term
Single use easy tos produce the shortcomings that resistance, extends the service life of medicament, has important meaning to the comprehensive treatment of germ resistance
Justice.
4, bactericidal composition provided by the invention, drug effect play rapidly, and the lasting period is long, and use cost is low, easy to use, save
Shi Shengli, popularization and application have huge economic benefit and social benefit.
Specific implementation mode
In order to keep the objectives, technical solutions, and advantages of the present invention more concise, present invention following specific examples
It illustrates, however, the present invention is by no means limited to these examples.It is as described below to be only the preferred embodiment of the present invention, it is used only for
The description present invention, should not be understood as limiting the scope of the present invention.It should be pointed out that all in the spirit and principles in the present invention
Within all any modification, equivalent and improvement etc. done, should all be included in the protection scope of the present invention.Therefore, this hair
The protection domain of bright patent should be determined by the appended claims.
Content described in embodiment is weight percentage.
Embodiment one：Tetramycin difenoconazole is to Rhizoctonia solani Kuhn (Thanatephorus cucumeris) of causing a disease
Toxicity Determination.
Subjects pick up from the rice sheath blight disease in field, method reference《People's Republic of China (PRC) agricultural industry criteria NY/T
1156.4-2006》。
According to Sun Yunpei's Method, the synergistic effect of pharmacy mix is evaluated according to co-toxicity coefficient (CTC), i.e. CTC≤80 are association
Same antagonism, 80 < CTC < 120 are joint action of antagonism, and CTC >=120 are synergistic function.Survey toxicity index
(ATI)=(EC of standard agent50The EC of/reagent agent50)×100；The toxicity index of theoretical toxicity index TTI=A medicaments ×
In mixture in toxicity index × mixture of the percentage composition+B medicaments of A medicaments B medicaments percentage composition；Co-toxicity coefficient (CTC)=
[mixture surveys toxicity index (ATI)/mixtures theoretical toxicity index (TTI)] × 100.
Table 1, tetramycin difenoconazole to cause a disease Rhizoctonia solani Kuhn (Thanatephorus cucumeris) interior
Toxicity test result
As shown in Table 1, tetramycin and difenoconazole mixture are 1:Between 1~80, Rhizoctonia solani
(Thanatephorus cucumeris) co-toxicity coefficient shows apparent synergistic effect 120 or more.
With reference to preparation method embodiment to further instruction of the present invention.
Embodiment two：10% tetramycin difenoconazole suspending agent.
Above-mentioned formula is crushed in advance in proportion, adds in sand mill and grinds, system is allocated after high shear mixing
Obtain 10% tetramycin difenoconazole suspending agent.
Embodiment three：10% tetramycin micro-emulsion of phenyl ether methyl cyclic-azole.
Acetone solution difenoconazole is first used, methanol, 602, MP-10, tetramycin, deionized water are sequentially added, it is each single
Material need to be stirred and is added after twenty minutes, you can 10% tetramycin micro-emulsion of phenyl ether methyl cyclic-azole is made.
Example IV：Tetramycin and difenoconazole composition for preventing and controlling rice sheath blight disease.
Rice sheath blight disease finds that initial stage is watered spraying, 10 days, 20 days control effects after medicine：0.1% tetramycin, 9.9% benzene
Ether methyl cyclic-azole suspending agent dosage 45g a.i./ha preventive effects 94.01%, 91.26%；0.1% tetramycin, 9.9% difenoconazole
Microemulsion dosage 45g a.i./ha preventive effects 94.78%, 91.83%；0.15% tetramycin aqua dosage 1.35g a.i./ha are anti-
Effect 83.52%, 79.40%；40% difenoconazole suspending agent dosage 90g a.i./ha preventive effects 90.19%, 85.08%.
Tetramycin and difenoconazole composition for preventing and controlling rice sheath blight disease are with obvious effects better than tetramycin, difenoconazole list
Agent significantly reduces when the amount ratio of active ingredient is used alone in combination medicament, and total active ingredient is also opposite to be reduced, to mitigate
Carrying capacity of environment reduces use cost, for farmer provides the more efficiently management tool of rice sheath blight disease.
Claims (4)
1. a kind of bactericidal composition containing tetramycin and difenoconazole, it is characterised in that：Active ingredient is tetramycin and benzene
Ether methyl cyclic-azole；The weight part ratio of tetramycin and difenoconazole is 1:60,1:70 or 1:80.
2. a kind of bactericidal composition containing tetramycin and difenoconazole according to claim 1, it is characterised in that：Four
The weight percent of mycin and difenoconazole weight summation in the composition is 1%~80%, remaining is insecticides adjuvant.
3. a kind of bactericidal composition containing tetramycin and difenoconazole according to claim 1, it is characterised in that：Institute
The dosage form for stating bactericidal composition is microemulsion or suspending agent.
4. a kind of bactericidal composition containing tetramycin and difenoconazole described in claim 1 draws in prevention Rhizoctonia solani Kuhn
Application in the rice sheath blight disease risen.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510359591.6A CN105028434B (en) | 2015-06-24 | 2015-06-24 | Bactericidal composition containing tetramycin and difenoconazole |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510359591.6A CN105028434B (en) | 2015-06-24 | 2015-06-24 | Bactericidal composition containing tetramycin and difenoconazole |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105028434A CN105028434A (en) | 2015-11-11 |
| CN105028434B true CN105028434B (en) | 2018-11-06 |
Family
ID=54435914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510359591.6A Active CN105028434B (en) | 2015-06-24 | 2015-06-24 | Bactericidal composition containing tetramycin and difenoconazole |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105028434B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105851024A (en) * | 2016-05-21 | 2016-08-17 | 泉州绿邦贸易有限公司 | Bactericide composition and application thereof |
| CN106818775A (en) * | 2017-02-28 | 2017-06-13 | 佛山市瑞生通科技有限公司 | A kind of bactericidal composition of the mycin of second containing fen and Difenoconazole |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103583532A (en) * | 2013-11-26 | 2014-02-19 | 辽宁微科生物工程有限公司 | Tetramycin complex and application |
| CN104757003A (en) * | 2015-04-24 | 2015-07-08 | 浙江世佳科技有限公司 | Sterilization composition containing tetramycin and difenoconazole as well as preparation and application thereof |
| CN104770380A (en) * | 2015-04-24 | 2015-07-15 | 浙江世佳科技有限公司 | Tetramycin and difenoconazole containing sterilizing aqueous agent and preparation method thereof |
-
2015
- 2015-06-24 CN CN201510359591.6A patent/CN105028434B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103583532A (en) * | 2013-11-26 | 2014-02-19 | 辽宁微科生物工程有限公司 | Tetramycin complex and application |
| CN104757003A (en) * | 2015-04-24 | 2015-07-08 | 浙江世佳科技有限公司 | Sterilization composition containing tetramycin and difenoconazole as well as preparation and application thereof |
| CN104770380A (en) * | 2015-04-24 | 2015-07-15 | 浙江世佳科技有限公司 | Tetramycin and difenoconazole containing sterilizing aqueous agent and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105028434A (en) | 2015-11-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106942240A (en) | A kind of microbicide compositions comprising emodin derivates and BIT | |
| CN105028434B (en) | Bactericidal composition containing tetramycin and difenoconazole | |
| CN102475085A (en) | Amistar-containing bactericidal composition | |
| CN103155929B (en) | Binary pesticide composition and application thereof | |
| CN102239878A (en) | Insecticide composite containing dinotefuran, preparation formulations and preparation method thereof | |
| CN102805085A (en) | Sterilization composition containing dimoxystrobin and thifluzamide | |
| CN106259366B (en) | A kind of microbicide compositions | |
| CN105010359B (en) | Bactericidal composition containing tetramycin and epoxiconazole | |
| CN102657184B (en) | Sterilizing composition containing phenylate diazole and thifluzamide | |
| CN104957153B (en) | Composition pesticide containing tetramycin and fluorine azoles ring bacterium amine | |
| CN101707999A (en) | Pesticide composition containing tebuconazole and validamycin A | |
| CN106212480B (en) | A kind of microbicide compositions | |
| CN105613511B (en) | A kind of agricultural pesticide composition and application thereof | |
| CN101263819B (en) | Indoxacarb and chlorfluazuron insecticidal composition | |
| CN104957154B (en) | Bactericidal composition containing tetramycin and kresoxim-methyl | |
| CN101731227A (en) | Compound pesticide containing etofenprox and pymetrozine | |
| CN106234378A (en) | A kind of microbicide compositions | |
| CN105519540A (en) | Pesticide composition containing benzovindiflupyr and tetraconazole | |
| CN103109815B (en) | Dimoxystrobin and azoxystrobin pesticide composition | |
| CN106259384B (en) | A kind of microbicide compositions | |
| CN110115268A (en) | A kind of composition pesticide containing Tolfenpyrad and fluopyram | |
| CN104381262B (en) | A kind of Herbicidal combinations containing AC 263222 and clethodim | |
| CN104521982B (en) | Containing fluorine ketone sulphur grass An He the Herbicidal combinations of metamifop | |
| CN106857546A (en) | Bactericidal composition and its application containing trifloxystrobin and fen second mycin | |
| CN105432622A (en) | Pesticide composition containing benzovindiflupyr and prothioconazole |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |