CN105012537A - External use medicine composition for treating chilblain, external use unguent for treating chilblain and preparation method of external use unguent - Google Patents

External use medicine composition for treating chilblain, external use unguent for treating chilblain and preparation method of external use unguent Download PDF

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CN105012537A
CN105012537A CN201510499369.6A CN201510499369A CN105012537A CN 105012537 A CN105012537 A CN 105012537A CN 201510499369 A CN201510499369 A CN 201510499369A CN 105012537 A CN105012537 A CN 105012537A
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weight portion
radix
weight
chilblain
radix angelicae
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万小耀
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Abstract

The invention provides an external use medicine composition for treating chilblain. The composition is composed of flos carthami, daphne genkwa, shikonin, coral ardisia root, tribulus terrestris, cutch, borneol, cinnamon, panax notoginseng, radix cynanchi panicullati, sodium chloride, radix angelicae dahuricae, sophora flavescens, fructus cnidii, achyranthes bidentata and angelica sinensis. The invention further provides external use unguent for treating chilblain and a preparation method of the external use unguent. The external use medicine composition and the external use unguent have the advantages of having the functions of invigorating blood circulation and dredging meridian, relieving swelling and pain, and relieving itching and eliminating discomfort.

Description

The externally-applied medicinal composition for the treatment of chilblain, external-applied ointment for the treatment of chilblain and preparation method thereof
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation, particularly relate to a kind of treat chilblain externally-applied medicinal composition, treatment chilblain external-applied ointment and preparation method thereof.
Background technology
Chilblain, after body is subject to cold invasion and attack, occurs in localized erythema's diseases associated with inflammation at tip position.It is low temperature above freezing combines caused by (clammy environment) exposure a kind of limitation imflammatory erythema infringement with high humility.Easily occur in the clammy environment of temperature less than 10 DEG C.Position is many at auricle, the place such as hands, foot, and local is rubescent, blue, swelling, and pain of itching, gets blister sometimes, rotten to the corn, ulceration, and knot is silly.
In southern mountain area, chilblain in winter is especially common.Southern area winter, without heating installation, mountain area height above sea level, to have a humid climate, and also needs work winter, does not wear footwear or trick and be directly exposed to and freeze in water during work; Many children whole winter barefoot or wear slippers, so south mild chilblain in winter is very common.
Go medicine to treat, one consuming time two costly, and for slight chilblain, most people often can not go clinic or hospitalize, self-treatment or let alone spontaneous recovery.In the face of different chilblain symptom, nonstandard treatment often cure the cycle long, can not patients in remission, even can cause other more serious problems.
Need a kind of Therapeutic Method of better chilblain.
Summary of the invention
An object of the present invention is to provide a kind of economy, pervasive, easy to use pharmaceutical composition withtreatment chilblain and various chilblain symptom.This object is achieved through the following technical solutions:
The externally-applied medicinal composition for the treatment of chilblain, is made up of following raw materials according by weight: Flos Carthami 80 ~ 100 weight portion, Flos Genkwa 80 ~ 100 weight portion; Radix Arnebiae (Radix Lithospermi) 20 ~ 30 weight portion, Radix Ardisiae Crenatae 20 ~ 30 weight portion, Fructus Tribuli 20 ~ 30 weight portion, catechu 20 ~ 30 weight portion; Borneolum Syntheticum 10 ~ 15 weight portion, Cortex Cinnamomi 10 ~ 15 weight portion, Radix Notoginseng 10 ~ 15 weight portion, Radix Cynanchi Paniculati 10 ~ 15 weight portion, sodium chloride 5 ~ 10 weight portion, the Radix Angelicae Dahuricae 5 ~ 10 weight portion, Radix Sophorae Flavescentis 5 ~ 10 weight portion, Fructus Cnidii 5 ~ 10 weight portion; Radix Achyranthis Bidentatae 20 ~ 30 weight portion, Radix Angelicae Sinensis 20 ~ 30 weight portion.
Preferably, be made up of following raw materials according by weight: Flos Carthami 80 weight portion, Flos Genkwa 90 weight portion; Radix Arnebiae (Radix Lithospermi) 20 weight portion, Radix Ardisiae Crenatae 20 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion; Borneolum Syntheticum 10 weight portion, Cortex Cinnamomi 12 weight portion, Radix Notoginseng 10 weight portion, Radix Cynanchi Paniculati 15 weight portion, sodium chloride 5 weight portion, the Radix Angelicae Dahuricae 7 weight portion, Radix Sophorae Flavescentis 7 weight portion, Fructus Cnidii 10 weight portion; Radix Achyranthis Bidentatae 25 weight portion, Radix Angelicae Sinensis 25 weight portion.
Preferably, be made up of following raw materials according by weight: Flos Carthami 90 weight portion, Flos Genkwa 100 weight portion; Radix Arnebiae (Radix Lithospermi) 25 weight portion, Radix Ardisiae Crenatae 25 weight portion, Fructus Tribuli 30 weight portion, catechu 30 weight portion; Borneolum Syntheticum 12 weight portion, Cortex Cinnamomi 15 weight portion, Radix Notoginseng 12 weight portion, Radix Cynanchi Paniculati 10 weight portion, sodium chloride 7 weight portion, the Radix Angelicae Dahuricae 10 weight portion, Radix Sophorae Flavescentis 10 weight portion, Fructus Cnidii 5 weight portion; Radix Achyranthis Bidentatae 20 weight portion, Radix Angelicae Sinensis 30 weight portion.
Preferably, be made up of following raw materials according by weight: Flos Carthami 100 weight portion, Flos Genkwa 80 weight portion; Radix Arnebiae (Radix Lithospermi) 30 weight portion, Radix Ardisiae Crenatae 30 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion; Borneolum Syntheticum 15 weight portion, Cortex Cinnamomi 10 weight portion, Radix Notoginseng 15 weight portion, Radix Cynanchi Paniculati 12 weight portion, sodium chloride 10 weight portion, the Radix Angelicae Dahuricae 5 weight portion, Radix Sophorae Flavescentis 5 weight portion, Fructus Cnidii 7 weight portion; Radix Achyranthis Bidentatae 30 weight portion, Radix Angelicae Sinensis 20 weight portion.
An object of the present invention is to provide a kind of external-applied ointment for the treatment of chilblain, and this object is achieved through the following technical solutions:
The external-applied ointment for the treatment of chilblain, is made up of following raw materials according by weight: Flos Carthami 80 ~ 100 weight portion, Flos Genkwa 80 ~ 100 weight portion; Radix Arnebiae (Radix Lithospermi) 20 ~ 30 weight portion, Radix Ardisiae Crenatae 20 ~ 30 weight portion, Fructus Tribuli 20 ~ 30 weight portion, catechu 20 ~ 30 weight portion; Borneolum Syntheticum 10 ~ 15 weight portion, Cortex Cinnamomi 10 ~ 15 weight portion, Radix Notoginseng 10 ~ 15 weight portion, Radix Cynanchi Paniculati 10 ~ 15 weight portion, sodium chloride 5 ~ 10 weight portion, the Radix Angelicae Dahuricae 5 ~ 10 weight portion, Radix Sophorae Flavescentis 5 ~ 10 weight portion, Fructus Cnidii 5 ~ 10 weight portion; Radix Achyranthis Bidentatae 20 ~ 30 weight portion, Radix Angelicae Sinensis 20 ~ 30 weight portion; Oleum Camelliae 1500 ~ 2000 weight portion, Cera Flava 300 ~ 600 weight portion.
Preferably, be made up of following raw materials according by weight: Flos Carthami 80 weight portion, Flos Genkwa 90 weight portion; Radix Arnebiae (Radix Lithospermi) 20 weight portion, Radix Ardisiae Crenatae 20 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion; Borneolum Syntheticum 10 weight portion, Cortex Cinnamomi 12 weight portion, Radix Notoginseng 10 weight portion, Radix Cynanchi Paniculati 15 weight portion, sodium chloride 5 weight portion, the Radix Angelicae Dahuricae 7 weight portion, Radix Sophorae Flavescentis 7 weight portion, Fructus Cnidii 10 weight portion; Radix Achyranthis Bidentatae 25 weight portion, Radix Angelicae Sinensis 25 weight portion; Oleum Camelliae 1500 weight portion, Cera Flava 350 weight portion.
Preferably, be made up of following raw materials according by weight: Flos Carthami 90 weight portion, Flos Genkwa 100 weight portion; Radix Arnebiae (Radix Lithospermi) 25 weight portion, Radix Ardisiae Crenatae 25 weight portion, Fructus Tribuli 30 weight portion, catechu 30 weight portion; Borneolum Syntheticum 12 weight portion, Cortex Cinnamomi 15 weight portion, Radix Notoginseng 12 weight portion, Radix Cynanchi Paniculati 10 weight portion, sodium chloride 7 weight portion, the Radix Angelicae Dahuricae 10 weight portion, Radix Sophorae Flavescentis 10 weight portion, Fructus Cnidii 5 weight portion; Radix Achyranthis Bidentatae 20 weight portion, Radix Angelicae Sinensis 30 weight portion; Oleum Camelliae 1800 weight portion, Cera Flava 600 weight portion.
Preferably, be made up of following raw materials according by weight: Flos Carthami 100 weight portion, Flos Genkwa 80 weight portion; Radix Arnebiae (Radix Lithospermi) 30 weight portion, Radix Ardisiae Crenatae 30 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion; Borneolum Syntheticum 15 weight portion, Cortex Cinnamomi 10 weight portion, Radix Notoginseng 15 weight portion, Radix Cynanchi Paniculati 12 weight portion, sodium chloride 10 weight portion, the Radix Angelicae Dahuricae 5 weight portion, Radix Sophorae Flavescentis 5 weight portion, Fructus Cnidii 7 weight portion; Radix Achyranthis Bidentatae 30 weight portion, Radix Angelicae Sinensis 20 weight portion; Oleum Camelliae 2000 weight portion, Cera Flava 450 weight portion.
An object of the present invention is to provide the manufacture method of the external-applied ointment of aforementioned therapies chilblain, and this object is achieved through the following technical solutions:
The manufacture method of the external-applied ointment for the treatment of chilblain, comprises the following steps: Borneolum Syntheticum, sodium chloride, Radix Notoginseng three taste raw material powder are broken into fine powder, crosses 150 ~ 200 mesh sieves; Oleum Camelliae be heated to and keep oil temperature at 180 ~ 200 ° of C, adding Radix Ardisiae Crenatae, catechu, Cortex Cinnamomi, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Achyranthis Bidentatae, Radix Angelicae Sinensis, explode withered or be deep-fried rear removing medicinal residues; Oil temperature be down to and remain on 150 ~ 160 ° of C, then adding Flos Carthami, Flos Genkwa, Radix Arnebiae (Radix Lithospermi), Fructus Tribuli, Radix Notoginseng, explode withered or be deep-fried rear removing medicinal residues; When oil temperature is cooled to 80 ~ 120 ° of C, add Cera Flava, stir and help Cera Flava to melt; Oil temperature be down to and remain on 50 ~ 70 ° of C, adding Borneolum Syntheticum, sodium chloride, stir evenly, let cool, to obtain final product.
Preferably, further comprising the steps of: Radix Ardisiae Crenatae, catechu, Cortex Cinnamomi, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Achyranthis Bidentatae, Radix Angelicae Sinensis powder are broken into coarse powder, cross 50 ~ 100 mesh sieves.
Preferably, further comprising the steps of: by Flos Carthami, Flos Genkwa, Radix Arnebiae (Radix Lithospermi), Fructus Tribuli chopping.
An object of the present invention is to provide the external hot compress paster for the treatment of chilblain, and this object is achieved through the following technical solutions:
The external hot compress paster for the treatment of chilblain, the following raw materials according comprised by weight is made: Flos Carthami 80 ~ 100 weight portion, Flos Genkwa 80 ~ 100 weight portion; Radix Arnebiae (Radix Lithospermi) 20 ~ 30 weight portion, Radix Ardisiae Crenatae 20 ~ 30 weight portion, Fructus Tribuli 20 ~ 30 weight portion, catechu 20 ~ 30 weight portion; Cortex Cinnamomi 10 ~ 15 weight portion, Radix Notoginseng 10 ~ 15 weight portion, Radix Cynanchi Paniculati 10 ~ 15 weight portion, the Radix Angelicae Dahuricae 5 ~ 10 weight portion, Radix Sophorae Flavescentis 5 ~ 10 weight portion, Fructus Cnidii 5 ~ 10 weight portion; Radix Achyranthis Bidentatae 20 ~ 30 weight portion, Radix Angelicae Sinensis 20 ~ 30 weight portion; Iron powder 3000 ~ 6000 weight portion, active carbon 300 ~ 600 weight portion, sodium chloride 100 ~ 300 weight portion.
Preferably, the following raw materials according comprised by weight is made: Flos Carthami 80 weight portion, Flos Genkwa 90 weight portion; Radix Arnebiae (Radix Lithospermi) 20 weight portion, Radix Ardisiae Crenatae 20 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion; Cortex Cinnamomi 12 weight portion, Radix Notoginseng 10 weight portion, Radix Cynanchi Paniculati 15 weight portion, the Radix Angelicae Dahuricae 7 weight portion, Radix Sophorae Flavescentis 7 weight portion, Fructus Cnidii 10 weight portion; Radix Achyranthis Bidentatae 25 weight portion, Radix Angelicae Sinensis 25 weight portion; Iron powder 3000 weight portion, active carbon 400 weight portion, sodium chloride 250 weight portion.
Alternatively, the following raw materials according comprised by weight is made: Flos Carthami 90 weight portion, Flos Genkwa 100 weight portion; Radix Arnebiae (Radix Lithospermi) 25 weight portion, Radix Ardisiae Crenatae 25 weight portion, Fructus Tribuli 30 weight portion, catechu 30 weight portion; Cortex Cinnamomi 15 weight portion, Radix Notoginseng 12 weight portion, Radix Cynanchi Paniculati 10 weight portion, the Radix Angelicae Dahuricae 10 weight portion, Radix Sophorae Flavescentis 10 weight portion, Fructus Cnidii 5 weight portion; Radix Achyranthis Bidentatae 20 weight portion, Radix Angelicae Sinensis 30 weight portion; Iron powder 4500 weight portion, active carbon 600 weight portion, sodium chloride 120 weight portion.
Alternatively, the following raw materials according comprised by weight is made: Flos Carthami 100 weight portion, Flos Genkwa 80 weight portion; Radix Arnebiae (Radix Lithospermi) 30 weight portion, Radix Ardisiae Crenatae 30 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion; Cortex Cinnamomi 10 weight portion, Radix Notoginseng 15 weight portion, Radix Cynanchi Paniculati 12 weight portion, the Radix Angelicae Dahuricae 5 weight portion, Radix Sophorae Flavescentis 5 weight portion, Fructus Cnidii 7 weight portion; Radix Achyranthis Bidentatae 30 weight portion, Radix Angelicae Sinensis 20 weight portion; Iron powder 6000 weight portion, active carbon 300 weight portion, sodium chloride 200 weight portion.
Preferably, Borneolum Syntheticum 10 ~ 15 weight portion is also comprised.
An object of the present invention is to provide the manufacture method of the external hot compress paster of aforesaid treatment chilblain, and this object is achieved through the following technical solutions:
Flos Carthami, Flos Genkwa, Radix Arnebiae (Radix Lithospermi), Radix Ardisiae Crenatae, Fructus Tribuli, catechu, Cortex Cinnamomi, Radix Notoginseng, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Achyranthis Bidentatae, Radix Angelicae Sinensis 14 taste raw material powder are broken into fine powder, cross 150 ~ 200 mesh sieves; Above 14 taste raw materials, iron powder, active carbon and sodium chloride are mixed to get mixture, to the sealing of described mixture air-isolation, and get final product.
Preferably, before sealing, use gauze according to predetermined weight part, subpackage is carried out to described mixture, after seal again.
Of the present invention group of thing mechanism of action is:
Monarch drug:
Flos Carthami, temperature, GUIXIN, Liver Channel, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain;
Flos Genkwa, pungent, warm, poisonous, return lung, spleen, kidney channel, removing fluid-retention by purgation, external parasite killing treat skin ulcer.
Ministerial drug:
Radix Arnebiae (Radix Lithospermi), sweet, salty, cold, GUIXIN, Liver Channel, clearing away heat and cooling blood, promoting blood circulation and detoxication, rash speckle removing;
Radix Ardisiae Crenatae, micro-hardship, pungent, flat, return lung, Liver Channel, removing toxic substances and promoting subsidence of swelling, promoting blood circulation and stopping pain, expelling wind and removing dampness;
Fructus Tribuli, pungent, bitter, tepor, slightly poisonous, return Liver Channel, suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic;
Catechu, puckery, be slightly cold, return lung, heart channel, promoting blood circulation and stopping pain, hemostasia and promoting granulation, removing dampness sore, removing heat from the lung and dissipating phlegm.
Adjuvant drug:
Borneolum Syntheticum, bitter, be slightly cold, GUIXIN, spleen, lung meridian, refreshment of having one's ideas straightened out, clearing away heat to alleviate pain;
Cortex Cinnamomi, pungent, sweet, hot greatly, return kidney, spleen, the heart, Liver Channel, mend fire supporing yang, guiding fire to origin, dispersing cold for relieving pain, promoting the flow of QI-blood by warming the meridian;
Radix Notoginseng, micro-hardship, temperature, return liver, stomach warp, dissipating blood stasis hemostasis, subduing swelling and relieving pain;
Radix Cynanchi Paniculati, temperature, returns liver, stomach warp, dispels the wind, removing dampness, pain relieving, antipruritic;
Sodium chloride, salty, cold, nontoxic, relieve inflammation or internal heat, removing heat from blood, removing toxic substances, softening the hard mass, parasite killing, antipruritic, sodium chloride can substitute with Sal in the present invention;
The Radix Angelicae Dahuricae, temperature, returns stomach, large intestine, lung meridian, the cold expelling that induces sweat, wind-expelling pain-stopping, a surname's clearing the nasal passage, dampness leukorrhagia stopping, detumescence and apocenosis;
Radix Sophorae Flavescentis, cold, GUIXIN, liver, stomach, large intestine, urinary bladder channel, heat clearing and damp drying, parasite killing, diuresis;
Fructus Cnidii, bitter, temperature, slightly poisonous, return kidney channel, dampness is dispeled the wind, killing parasites for relieving itching, warming the kidney to invigorate YANG.
Make medicine:
Radix Achyranthis Bidentatae, sweet, sour, flat, return liver, kidney channel, eliminating blood stasis and inducing menstruation, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards;
Radix Angelicae Sinensis, sweet, pungent, warm, return liver, the heart, spleen channel, enrich blood invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
Beneficial effect of the present invention is:
The effect of easypro network, reducing swelling and alleviating pain, the antipruritic sense of discomfort that disappears of invigorating blood circulation.Be applicable to treat various mild chilblain and economy of drawing materials.The external hot compress paster for the treatment of chilblain adds thermotherapy, and drug effect continuingly acts on affected part, and effect more.
The optional using method of the present invention: the externally-applied medicinal composition for the treatment of chilblain being carried out decocting in water and boils liquid to obtain, washing affected part with boiling vacuole, or boil the towel hot compress of liquid in patient with adhesional wetting; The external-applied ointment for the treatment of chilblain is consistent with common ointment using method.Use amount, frequency of utilization elect according to individual concrete condition.The using method of the external hot compress paster for the treatment of chilblain, under several to plaster jog before using, plaster spreads on affected part, can pad clean ventilative thing, preferably with gauze to prevent from scalding between skin and plaster, be fixed plaster afterwards, the mode that gauze periphery can be selected to be wound around is fixed.
The present invention is through 20 person-times of verification experimental verifications among the people, and Be very effective, effective percentage reaches 100%, remission 85% in 1 day, and recovery from illness in 5 days reaches 90%, and following is the present invention's 3 specific experiment examples.
Experimental example 1
Lee, man, in winter, left ear plays chilblain, and appearance is red and swollen, impact image, and use the externally-applied medicinal composition for the treatment of burn to embathe, onset after a day, redness disappears to some extent, embathes 2 every day, fully recovers after 5 days, without other senses of discomfort.
Experimental example 2
Luo, female, points long chilblain and has scratchiness, uses the external hot compress paster for the treatment of chilblain, once uses 10 hours, every other day use again, onset after a day, and after three days, pruritus is eliminated, and fully recovers after six days.
Experimental example 3
Chen, female, has distending pain sense after the long chilblain of foot, and after noon sky heat, distending pain sense more very, and with gauze wrapping behind the external-applied ointment coating affected part for the treatment of chilblain, within one day one, change, distending pain sense in a day alleviates, and distending pain sense in two days is eliminated, and swelling in four days is eliminated, uncomfortable without other.
The chilblain it should be noted that the present invention forbids eating, being only applicable to without wound, and for the careful use of anemia of pregnant woman.
Detailed description of the invention
Below by way of specific embodiment, the present invention is described in detail.
Embodiment 1
The externally-applied medicinal composition getting treatment chilblain is joined: Flos Carthami 80 weight portion, Flos Genkwa 90 weight portion according to the raw material of following parts by weight; Radix Arnebiae (Radix Lithospermi) 20 weight portion, Radix Ardisiae Crenatae 20 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion; Borneolum Syntheticum 10 weight portion, Cortex Cinnamomi 12 weight portion, Radix Notoginseng 10 weight portion, Radix Cynanchi Paniculati 15 weight portion, sodium chloride 5 weight portion, the Radix Angelicae Dahuricae 7 weight portion, Radix Sophorae Flavescentis 7 weight portion, Fructus Cnidii 10 weight portion; Radix Achyranthis Bidentatae 25 weight portion, Radix Angelicae Sinensis 25 weight portion.
Embodiment 2
The externally-applied medicinal composition for the treatment of chilblain, is made up of following raw materials according by weight: Flos Carthami 90 weight portion, Flos Genkwa 100 weight portion; Radix Arnebiae (Radix Lithospermi) 25 weight portion, Radix Ardisiae Crenatae 25 weight portion, Fructus Tribuli 30 weight portion, catechu 30 weight portion; Borneolum Syntheticum 12 weight portion, Cortex Cinnamomi 15 weight portion, Radix Notoginseng 12 weight portion, Radix Cynanchi Paniculati 10 weight portion, sodium chloride 7 weight portion, the Radix Angelicae Dahuricae 10 weight portion, Radix Sophorae Flavescentis 10 weight portion, Fructus Cnidii 5 weight portion; Radix Achyranthis Bidentatae 20 weight portion, Radix Angelicae Sinensis 30 weight portion.
Embodiment 3
The externally-applied medicinal composition getting treatment chilblain is joined: Flos Carthami 100 weight portion, Flos Genkwa 80 weight portion according to the raw material of following parts by weight; Radix Arnebiae (Radix Lithospermi) 30 weight portion, Radix Ardisiae Crenatae 30 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion; Borneolum Syntheticum 15 weight portion, Cortex Cinnamomi 10 weight portion, Radix Notoginseng 15 weight portion, Radix Cynanchi Paniculati 12 weight portion, sodium chloride 10 weight portion, the Radix Angelicae Dahuricae 5 weight portion, Radix Sophorae Flavescentis 5 weight portion, Fructus Cnidii 7 weight portion; Radix Achyranthis Bidentatae 30 weight portion, Radix Angelicae Sinensis 20 weight portion.
Embodiment 4
The external-applied ointment for the treatment of chilblain is made up of following raw materials according by weight: the externally-applied medicinal composition of the treatment chilblain of any embodiment in embodiment 1 ~ 3, Oleum Camelliae 1500 ~ 2000 weight portion, Cera Flava 300 ~ 600 weight portion.
Embodiment 5
The external-applied ointment for the treatment of chilblain is made up of following raw materials according by weight:
Flos Carthami 80 weight portion, Flos Genkwa 90 weight portion; Radix Arnebiae (Radix Lithospermi) 20 weight portion, Radix Ardisiae Crenatae 20 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion; Borneolum Syntheticum 10 weight portion, Cortex Cinnamomi 12 weight portion, Radix Notoginseng 10 weight portion, Radix Cynanchi Paniculati 15 weight portion, sodium chloride 5 weight portion, the Radix Angelicae Dahuricae 7 weight portion, Radix Sophorae Flavescentis 7 weight portion, Fructus Cnidii 10 weight portion; Radix Achyranthis Bidentatae 25 weight portion, Radix Angelicae Sinensis 25 weight portion; Oleum Camelliae 1500 weight portion, Cera Flava 350 weight portion.
Embodiment 6
The external-applied ointment for the treatment of chilblain is made up of following raw materials according by weight:
Flos Carthami 90 weight portion, Flos Genkwa 100 weight portion; Radix Arnebiae (Radix Lithospermi) 25 weight portion, Radix Ardisiae Crenatae 25 weight portion, Fructus Tribuli 30 weight portion, catechu 30 weight portion; Borneolum Syntheticum 12 weight portion, Cortex Cinnamomi 15 weight portion, Radix Notoginseng 12 weight portion, Radix Cynanchi Paniculati 10 weight portion, sodium chloride 7 weight portion, the Radix Angelicae Dahuricae 10 weight portion, Radix Sophorae Flavescentis 10 weight portion, Fructus Cnidii 5 weight portion; Radix Achyranthis Bidentatae 20 weight portion, Radix Angelicae Sinensis 30 weight portion; Oleum Camelliae 1800 weight portion, Cera Flava 600 weight portion.
Embodiment 7
The external-applied ointment for the treatment of chilblain is made up of following raw materials according by weight:
Flos Carthami 100 weight portion, Flos Genkwa 80 weight portion; Radix Arnebiae (Radix Lithospermi) 30 weight portion, Radix Ardisiae Crenatae 30 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion; Borneolum Syntheticum 15 weight portion, Cortex Cinnamomi 10 weight portion, Radix Notoginseng 15 weight portion, Radix Cynanchi Paniculati 12 weight portion, sodium chloride 10 weight portion, the Radix Angelicae Dahuricae 5 weight portion, Radix Sophorae Flavescentis 5 weight portion, Fructus Cnidii 7 weight portion; Radix Achyranthis Bidentatae 30 weight portion, Radix Angelicae Sinensis 20 weight portion; Oleum Camelliae 2000 weight portion, Cera Flava 450 weight portion.
Embodiment 8
The manufacture method of the external-applied ointment for the treatment of chilblain, comprises the following steps:
Borneolum Syntheticum, sodium chloride, Radix Notoginseng three taste raw material powder are broken into fine powder, cross 150 ~ 200 mesh sieves;
By Flos Carthami, Flos Genkwa, Radix Arnebiae (Radix Lithospermi), Radix Ardisiae Crenatae, Fructus Tribuli, catechu, Cortex Cinnamomi, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Achyranthis Bidentatae, the raw material cutting of Radix Angelicae Sinensis 13 taste or pulverizing, the time that the contact surface increasing 13 taste raw materials expends to reduce later step; Wherein Radix Ardisiae Crenatae, catechu, Cortex Cinnamomi, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Achyranthis Bidentatae, Radix Angelicae Sinensis powder are broken into coarse powder, cross 50 ~ 100 mesh sieves.
Oleum Camelliae be heated to and keep oil temperature at 180 ~ 200 ° of C, adding Radix Ardisiae Crenatae, catechu, Cortex Cinnamomi, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Achyranthis Bidentatae, Radix Angelicae Sinensis, nine taste raw materials exploded withered or be deep-fried rear removing medicinal residues and obtain the first fried liquid;
First fried liquid temp be down to and remained on 150 ~ 160 ° of C, then adds Flos Carthami, Flos Genkwa, Radix Arnebiae (Radix Lithospermi), Fructus Tribuli, Radix Notoginseng five tastes raw material, five tastes raw material exploded withered or be deep-fried rear removing medicinal residues;
When oil temperature is cooled to 80 ~ 120 ° of C, add Cera Flava, stir and help Cera Flava to melt;
Oil temperature be down to and remain on 50 ~ 70 ° of C, adding Borneolum Syntheticum, sodium chloride, stir evenly, let cool, to obtain final product.
Particularly, Oleum Camelliae carries out, in frying process, can concentrating and adding raw material to raw material, is progressively skimmed being deep-fried fried withered medicinal residues; Also can classify and add raw material in batches, the raw material of same batch is substantially all deep-fried fried withered rear filtration, leaves filtrate and carries out next batch frying.
The preparation method of embodiment 8 can be used for the preparation of the external-applied ointment of the treatment chilblain of embodiment 4,5,6,7.
Embodiment 9
The external hot compress paster for the treatment of chilblain is made up of following raw materials according by weight:
Flos Carthami 80 weight portion, Flos Genkwa 90 weight portion; Radix Arnebiae (Radix Lithospermi) 20 weight portion, Radix Ardisiae Crenatae 20 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion; Cortex Cinnamomi 12 weight portion, Radix Notoginseng 10 weight portion, Radix Cynanchi Paniculati 15 weight portion, the Radix Angelicae Dahuricae 7 weight portion, Radix Sophorae Flavescentis 7 weight portion, Fructus Cnidii 10 weight portion; Radix Achyranthis Bidentatae 25 weight portion, Radix Angelicae Sinensis 25 weight portion; Iron powder 3000 weight portion, active carbon 400 weight portion, sodium chloride 250 weight portion.
Embodiment 10
The external hot compress paster for the treatment of chilblain is made up of following raw materials according by weight:
Flos Carthami 90 weight portion, Flos Genkwa 100 weight portion; Radix Arnebiae (Radix Lithospermi) 25 weight portion, Radix Ardisiae Crenatae 25 weight portion, Fructus Tribuli 30 weight portion, catechu 30 weight portion; Cortex Cinnamomi 15 weight portion, Radix Notoginseng 12 weight portion, Radix Cynanchi Paniculati 10 weight portion, the Radix Angelicae Dahuricae 10 weight portion, Radix Sophorae Flavescentis 10 weight portion, Fructus Cnidii 5 weight portion; Radix Achyranthis Bidentatae 20 weight portion, Radix Angelicae Sinensis 30 weight portion; Iron powder 4500 weight portion, active carbon 600 weight portion, sodium chloride 120 weight portion.
Embodiment 11
The external hot compress paster for the treatment of chilblain is made up of following raw materials according by weight:
Flos Carthami 100 weight portion, Flos Genkwa 80 weight portion; Radix Arnebiae (Radix Lithospermi) 30 weight portion, Radix Ardisiae Crenatae 30 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion; Cortex Cinnamomi 10 weight portion, Radix Notoginseng 15 weight portion, Radix Cynanchi Paniculati 12 weight portion, the Radix Angelicae Dahuricae 5 weight portion, Radix Sophorae Flavescentis 5 weight portion, Fructus Cnidii 7 weight portion; Radix Achyranthis Bidentatae 30 weight portion, Radix Angelicae Sinensis 20 weight portion; Iron powder 6000 weight portion, active carbon 300 weight portion, sodium chloride 200 weight portion.
Embodiment 12
The external hot compress paster for the treatment of chilblain is made up of following raw materials according by weight:
Treat in embodiment 9,10 or 11 on the basis of the external hot compress paster of chilblain, also comprise Borneolum Syntheticum 10 ~ 15 weight portion.
Embodiment 13
The manufacture method of the external hot compress paster for the treatment of chilblain, comprises the following steps:
Flos Carthami, Flos Genkwa, Radix Arnebiae (Radix Lithospermi), Radix Ardisiae Crenatae, Fructus Tribuli, catechu, Cortex Cinnamomi, Radix Notoginseng, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Achyranthis Bidentatae, Radix Angelicae Sinensis 14 taste raw material powder are broken into fine powder, cross 150 ~ 200 mesh sieves;
Above 14 taste raw materials, iron powder, active carbon and sodium chloride are mixed to get mixture;
To the sealing of described mixture air-isolation, and to get final product.
Preferably, before sealing, use gauze according to predetermined weight part, subpackage is carried out to described mixture, after seal again.
The preparation method of embodiment 13 can be used for the preparation of the external hot compress paster of the treatment chilblain of embodiment 9,10,11.
In various embodiments of the present invention, mentioned raw material all preferably meets the raw material of Pharmacopoeia of the People's Republic of China quality standard.
Above-described embodiment, the just one of the present invention's more preferably detailed description of the invention, the usual change that those skilled in the art carries out within the scope of technical solution of the present invention and replacing all should be included in protection scope of the present invention.

Claims (10)

1. treat an externally-applied medicinal composition for chilblain, it is characterized in that, be made up of following raw materials according by weight: Flos Carthami 80 ~ 100 weight portion, Flos Genkwa 80 ~ 100 weight portion;
Radix Arnebiae (Radix Lithospermi) 20 ~ 30 weight portion, Radix Ardisiae Crenatae 20 ~ 30 weight portion, Fructus Tribuli 20 ~ 30 weight portion, catechu 20 ~ 30 weight portion;
Borneolum Syntheticum 10 ~ 15 weight portion, Cortex Cinnamomi 10 ~ 15 weight portion, Radix Notoginseng 10 ~ 15 weight portion, Radix Cynanchi Paniculati 10 ~ 15 weight portion, sodium chloride 5 ~ 10 weight portion, the Radix Angelicae Dahuricae 5 ~ 10 weight portion, Radix Sophorae Flavescentis 5 ~ 10 weight portion, Fructus Cnidii 5 ~ 10 weight portion;
Radix Achyranthis Bidentatae 20 ~ 30 weight portion, Radix Angelicae Sinensis 20 ~ 30 weight portion.
2. the externally-applied medicinal composition for the treatment of chilblain according to claim 1, is characterized in that, is made up of following raw materials according by weight: Flos Carthami 80 weight portion, Flos Genkwa 90 weight portion;
Radix Arnebiae (Radix Lithospermi) 20 weight portion, Radix Ardisiae Crenatae 20 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion;
Borneolum Syntheticum 10 weight portion, Cortex Cinnamomi 12 weight portion, Radix Notoginseng 10 weight portion, Radix Cynanchi Paniculati 15 weight portion, sodium chloride 5 weight portion, the Radix Angelicae Dahuricae 7 weight portion, Radix Sophorae Flavescentis 7 weight portion, Fructus Cnidii 10 weight portion;
Radix Achyranthis Bidentatae 25 weight portion, Radix Angelicae Sinensis 25 weight portion.
3. the externally-applied medicinal composition for the treatment of chilblain according to claim 1, is characterized in that, is made up of following raw materials according by weight: Flos Carthami 90 weight portion, Flos Genkwa 100 weight portion;
Radix Arnebiae (Radix Lithospermi) 25 weight portion, Radix Ardisiae Crenatae 25 weight portion, Fructus Tribuli 30 weight portion, catechu 30 weight portion;
Borneolum Syntheticum 12 weight portion, Cortex Cinnamomi 15 weight portion, Radix Notoginseng 12 weight portion, Radix Cynanchi Paniculati 10 weight portion, sodium chloride 7 weight portion, the Radix Angelicae Dahuricae 10 weight portion, Radix Sophorae Flavescentis 10 weight portion, Fructus Cnidii 5 weight portion;
Radix Achyranthis Bidentatae 20 weight portion, Radix Angelicae Sinensis 30 weight portion.
4. the externally-applied medicinal composition for the treatment of chilblain according to claim 1, is characterized in that, is made up of following raw materials according by weight: Flos Carthami 100 weight portion, Flos Genkwa 80 weight portion;
Radix Arnebiae (Radix Lithospermi) 30 weight portion, Radix Ardisiae Crenatae 30 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion;
Borneolum Syntheticum 15 weight portion, Cortex Cinnamomi 10 weight portion, Radix Notoginseng 15 weight portion, Radix Cynanchi Paniculati 12 weight portion, sodium chloride 10 weight portion, the Radix Angelicae Dahuricae 5 weight portion, Radix Sophorae Flavescentis 5 weight portion, Fructus Cnidii 7 weight portion;
Radix Achyranthis Bidentatae 30 weight portion, Radix Angelicae Sinensis 20 weight portion.
5. treat an external-applied ointment for chilblain, it is characterized in that, be made up of following raw materials according by weight:
Flos Carthami 80 ~ 100 weight portion, Flos Genkwa 80 ~ 100 weight portion;
Radix Arnebiae (Radix Lithospermi) 20 ~ 30 weight portion, Radix Ardisiae Crenatae 20 ~ 30 weight portion, Fructus Tribuli 20 ~ 30 weight portion, catechu 20 ~ 30 weight portion;
Borneolum Syntheticum 10 ~ 15 weight portion, Cortex Cinnamomi 10 ~ 15 weight portion, Radix Notoginseng 10 ~ 15 weight portion, Radix Cynanchi Paniculati 10 ~ 15 weight portion, sodium chloride 5 ~ 10 weight portion, the Radix Angelicae Dahuricae 5 ~ 10 weight portion, Radix Sophorae Flavescentis 5 ~ 10 weight portion, Fructus Cnidii 5 ~ 10 weight portion;
Radix Achyranthis Bidentatae 20 ~ 30 weight portion, Radix Angelicae Sinensis 20 ~ 30 weight portion;
Oleum Camelliae 1500 ~ 2000 weight portion, Cera Flava 300 ~ 600 weight portion.
6. the external-applied ointment for the treatment of chilblain according to claim 5, is characterized in that, is made up of following raw materials according by weight: Flos Carthami 80 weight portion, Flos Genkwa 90 weight portion;
Radix Arnebiae (Radix Lithospermi) 20 weight portion, Radix Ardisiae Crenatae 20 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion;
Borneolum Syntheticum 10 weight portion, Cortex Cinnamomi 12 weight portion, Radix Notoginseng 10 weight portion, Radix Cynanchi Paniculati 15 weight portion, sodium chloride 5 weight portion, the Radix Angelicae Dahuricae 7 weight portion, Radix Sophorae Flavescentis 7 weight portion, Fructus Cnidii 10 weight portion;
Radix Achyranthis Bidentatae 25 weight portion, Radix Angelicae Sinensis 25 weight portion;
Oleum Camelliae 1500 weight portion, Cera Flava 350 weight portion.
7. the external-applied ointment for the treatment of chilblain according to claim 5, is characterized in that, is made up of following raw materials according by weight:
Flos Carthami 90 weight portion, Flos Genkwa 100 weight portion;
Radix Arnebiae (Radix Lithospermi) 25 weight portion, Radix Ardisiae Crenatae 25 weight portion, Fructus Tribuli 30 weight portion, catechu 30 weight portion;
Borneolum Syntheticum 12 weight portion, Cortex Cinnamomi 15 weight portion, Radix Notoginseng 12 weight portion, Radix Cynanchi Paniculati 10 weight portion, sodium chloride 7 weight portion, the Radix Angelicae Dahuricae 10 weight portion, Radix Sophorae Flavescentis 10 weight portion, Fructus Cnidii 5 weight portion;
Radix Achyranthis Bidentatae 20 weight portion, Radix Angelicae Sinensis 30 weight portion;
Oleum Camelliae 1800 weight portion, Cera Flava 600 weight portion.
8. the external-applied ointment for the treatment of chilblain according to claim 5, is characterized in that, is made up of following raw materials according by weight:
Flos Carthami 100 weight portion, Flos Genkwa 80 weight portion;
Radix Arnebiae (Radix Lithospermi) 30 weight portion, Radix Ardisiae Crenatae 30 weight portion, Fructus Tribuli 25 weight portion, catechu 25 weight portion;
Borneolum Syntheticum 15 weight portion, Cortex Cinnamomi 10 weight portion, Radix Notoginseng 15 weight portion, Radix Cynanchi Paniculati 12 weight portion, sodium chloride 10 weight portion, the Radix Angelicae Dahuricae 5 weight portion, Radix Sophorae Flavescentis 5 weight portion, Fructus Cnidii 7 weight portion;
Radix Achyranthis Bidentatae 30 weight portion, Radix Angelicae Sinensis 20 weight portion;
Oleum Camelliae 2000 weight portion, Cera Flava 450 weight portion.
9. treat a manufacture method for the external-applied ointment of chilblain described in claims 5 to 8, it is characterized in that, comprise the following steps:
Borneolum Syntheticum, sodium chloride, Radix Notoginseng three taste raw material powder are broken into fine powder, cross 150 ~ 200 mesh sieves;
Oleum Camelliae be heated to and keep oil temperature at 180 ~ 200 ° of C, adding Radix Ardisiae Crenatae, catechu, Cortex Cinnamomi, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Achyranthis Bidentatae, Radix Angelicae Sinensis, explode withered or be deep-fried rear removing medicinal residues;
Oil temperature be down to and remain on 150 ~ 160 ° of C, then adding Flos Carthami, Flos Genkwa, Radix Arnebiae (Radix Lithospermi), Fructus Tribuli, Radix Notoginseng, explode withered or be deep-fried rear removing medicinal residues;
When oil temperature is cooled to 80 ~ 120 ° of C, add Cera Flava, stir and help Cera Flava to melt;
Oil temperature be down to and remain on 50 ~ 70 ° of C, adding Borneolum Syntheticum, sodium chloride, stir evenly, let cool, to obtain final product.
10. the manufacture method of the external-applied ointment for the treatment of chilblain according to claim 9, it is characterized in that, further comprising the steps of: Radix Ardisiae Crenatae, catechu, Cortex Cinnamomi, Radix Cynanchi Paniculati, the Radix Angelicae Dahuricae, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Achyranthis Bidentatae, Radix Angelicae Sinensis powder are broken into coarse powder, cross 50 ~ 100 mesh sieves.
CN201510499369.6A 2015-08-15 2015-08-15 External use medicine composition for treating chilblain, external use unguent for treating chilblain and preparation method of external use unguent Pending CN105012537A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1444976A (en) * 2003-04-16 2003-10-01 王朝岭 Preparation of Chinese herbal medicine for treating cold injury, various indurations and swelling, pain as well as its preparing method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1444976A (en) * 2003-04-16 2003-10-01 王朝岭 Preparation of Chinese herbal medicine for treating cold injury, various indurations and swelling, pain as well as its preparing method

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
周永坤: "《实用中医外科金方》", 30 April 2008, 中医古籍出版社 *
张彦祥: "中药外敷治疗冻疮46例", 《中医外治杂志》 *
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