CN105012485A - Traditional Chinese medicine granule for treating neonatal jaundice - Google Patents
Traditional Chinese medicine granule for treating neonatal jaundice Download PDFInfo
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- CN105012485A CN105012485A CN201510496881.5A CN201510496881A CN105012485A CN 105012485 A CN105012485 A CN 105012485A CN 201510496881 A CN201510496881 A CN 201510496881A CN 105012485 A CN105012485 A CN 105012485A
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Abstract
The invention relates to a traditional Chinese medicine granule for treating neonatal jaundice. The traditional Chinese medicine granule is prepared from, by weight, 10-15 parts of herba artemisiae scopariae, 10-15 parts of fructus gardeniae, 10-15 parts of abrus cantoniensis hance, 10-15 parts of folium isatidis, 5-10 parts of paeonia suffruticosa, 6-10 parts of radix gentianae, 5-10 parts of curcuma, 10-15 parts of spreading hedyotis herb, 5-10 parts of fructus aurantii immaturus, 4-6 parts of rhubarb, 10-15 parts of dahurian patrinia herb, 10-15 parts of lophantherum gracile and 5-10 parts of radix glycyrrhizae. The traditional Chinese medicine granule is easy to prepare, convenient to take, safe, reliable, rapid and remarkable in curative effect, stable, free of repeated attack and special for neonatal jaundice and other jaundice.
Description
Technical field
The invention belongs to application in TCM field, particularly a kind of Chinese medicinal granule for the treatment of neonatal jaundice.
Background technology
Method and the curative effect of medication of existing various treatment neonatal jaundice are unsatisfactory, easily produce untoward reaction, more do not have a kind of Chinese patent medicine that can substitute transfusion change-blood of having an injection.Existing quasi-drugs, kind is single, and the state of an illness is more effective in cure, and aggravation is just invalid.Invention has been seriation research, invented and specially controlled neonatal jaundice, comprised a series of diseases (normal human serum bilirubin 34.2umol/L) that serum mesobilirubin increases, the Chinese medicine nostrum being feature with icteric sclera, skin Huang, yellowish urine, can cure.
Jaundice is neonatal commonly encountered diseases.Neonate one is born from oxygen-free environment is vertical and is transferred aerobic environment to, erythrocyte mortality in blood, add breast milk (human milk) or have the many reasons such as shortage or haemolysis, especially Rh haemolysis of infection or various enzyme, cause blood of neonate mesobilirubin to increase, severe patient can cause bilirubin encephalopathy, bilirubin encephalopathy, once occur, seriously will affect the growth promoter of children's, even permanent disbility or sky folding.The Chinese medicine of current treatment neonatal jaundice has Yinzhihuang" granula, and separately have blue light illumination, vein to input albumin etc., the treatment for slight jaundice still has certain curative effect, but severe jaundice only takes exchange transfusion.
Exchange transfusion operation is numerous and diverse, and equipment is high-end, expensive price, is not that ordinary person institute is receptible.Therefore need to seek a kind of drug effect better, can severe jaundice be treated more comprehensively thus the new drug of replacement exchange transfusion.
The Chinese medicinal granule for the treatment of neonatal jaundice has effect of heat clearing away, removing toxic substances, dampness removing.The bilirubin that its feature one is heat-clearing and toxic substances removing, raise in hepatoprotective, control serum no longer occurs.Two is just excreted out from two rapidly by the bilirubin in body.Thus efficiently avoid the generation of bilirubin encephalopathy, effectively protect the function of liver.
Summary of the invention
The present invention, in order to make up the deficiencies in the prior art, provides a kind of Chinese medicinal granule preparing treatment neonatal jaundice simple, evident in efficacy.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicinal granule for neonatal jaundice, be made up of the raw material of following parts by weight:
Herba Artemisiae Scopariae 10-15 part, Fructus Gardeniae 10-15 part, Herba Abri 10-15 part, Folium Isatidis 10 1 15 parts, Fructus Aurantii Immaturus 5-10 part, Radix Gentianae 6-10 part, Radix Curcumae 5-10 part, Cortex Moutan 5-10 part, Herba Lophatheri 10-15 part, Herba Hedyotidis Diffusae 10-15 part, Herba Patriniae 10-15 part, Radix Et Rhizoma Rhei 4-6 part, Radix Glycyrrhizae 5-10 part.
The weight proportion of its preferred each raw material is:
Herba Artemisiae Scopariae 12 parts, Fructus Gardeniae 12 parts, Herba Abri 12 parts, Folium Isatidis 12 parts, Fructus Aurantii Immaturus 8 parts, Radix Gentianae 8 parts, Radix Curcumae 8 parts, Cortex Moutan 8 parts, Herba Lophatheri 12 parts, Herba Hedyotidis Diffusae 12 parts, Herba Patriniae 12 parts, Radix Et Rhizoma Rhei 5 parts, 6 parts, Radix Glycyrrhizae
Raw material of the present invention is after cleaning up, add the water soaking of 12 times of weight after two hours, after intense fire is boiled, change three times at a simmer, first time decocts 1 hour, and second time and third time decoct 40 minutes respectively, merges after decocting concentration of liquid medicine paste three times, add dextrin, white sugar mix homogeneously, make granule with mesh screen and obtain product.
Wherein, the weight ratio of described Chinese medicinal ointment, dextrin, white sugar is 1:1:1.5, and mesh screen is 40 order specifications, obtains product after granule dries.
The present invention adopt the pharmaceutical characteristic of raw material as follows:
Herba Artemisiae Scopariae: bitter, be slightly cold; Clearing away heat-damp and promoting diuresis, protects the liver, jaundice eliminating.Cure mainly: jaundice, eczema, eczema.
Fructus Gardeniae: bitter, cold; Pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Cure mainly: jaundice due to damp-heat, calentura are vexed, gloomy.
Herba Abri: sweet, micro-hardship, cool; Heat-clearing and toxic substances removing.Cure mainly: jaundice due to damp-heat, acute hepatitis, chronic hepatitis.
Folium Isatidis: bitter, cold; The clear speckle of heat-clearing and toxic substances removing, removing heat from blood.Cure mainly: the high heat of the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, coma, a speckle.
Fructus Aurantii Immaturus: bitter, pungent; Removing food stagnancy, except painful abdominal mass, hepatic cholagogic.Cure mainly: food stagnation constipation, stagnation of phlegm-damp.
Radix Gentianae: bitter, cold; Heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.Cure mainly: jaundice due to damp-heat, acute infantile convulsion.
Radix Curcumae: pungent, bitter, cold; The cool heart clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice.Cure mainly: jaundice due to damp-heat, heat in blood are hemorrhage.
Cortex Moutan: bitter, pungent, be slightly cold; Clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.Cure mainly: heat in blood is spitted blood, epistaxis and various hemorrhage.
Herba Lophatheri: sweet, light, cold; Clearing heat and relieving fidgetness, diuresis.Cure mainly: calentura excessive thirst, jaundice due to damp-heat.
Herba Hedyotidis Diffusae: bitter, sweet, cold; Heat-clearing and toxic substances removing, dampness removing, eliminating carbuncle.Cure mainly: carbuncle sore tumefacting virus, dysuria, jaundice eliminating.
Herba Patriniae: pungent, bitter, be slightly cold; Heat-clearing and toxic substances removing, stasis-dispelling and pain-killing, eliminating carbuncle evacuation of pus.Cure mainly: intestinal liver lung abscess, dampness removing jaundice eliminating.
Radix Et Rhizoma Rhei: bitter, cold; Clearing away heat-fire, rush down that lower rose is long-pending, removing toxic substances hemostasis.Cure mainly: gastrointestinal retention, herpes simplex are swollen, heat in blood is hemorrhage.
Radix Glycyrrhizae: sweet, flat; QI invigorating invigorating middle warmer, the mitigation property of medicine.Cure mainly: insufficiency of the spleen weak, anorexia and loose stool, coordinating the actions of various ingredients in a prescription.
In formula, monarch drug: Herba Artemisiae Scopariae, Fructus Gardeniae, the key medicine in heat-clearing and toxic substances removing, the dampness removing jaundice eliminating side of being; Ministerial drug: Radix Curcumae, Radix Gentianae, Herba Abri, Fructus Aurantii Immaturus, Radix Et Rhizoma Rhei, clearing away heat-damp and promoting diuresis, hepatoprotective, function of gallbladder promoting, logical stool, rib monarch drug strengthens the merit of heat-clearing and dampness-resolving; Adjuvant drug: Herba Lophatheri, Herba Hedyotidis Diffusae, Folium Isatidis, Herba Patriniae, further heat-clearing and toxic substances removing, dampness removing, diuresis; Make medicine: Cortex Moutan, Radix Glycyrrhizae, clearing away heat and cooling blood, QI invigorating, coordinating the actions of various ingredients in a prescription.Full side plays effect of heat-clearing and toxic substances removing, dampness removing jaundice eliminating, hepatoprotective altogether.
Clinical observation
(1) physical data
The present invention in 2008 so far, carries out clinical observation treatment to thousands of neonatal patient, and the course of disease and age in days are not etc.
(2) Therapeutic Method: directly take medicine of the present invention, every day 3 times, be grown up everyone each 15-20g; Everyone each kg body weight 0.5g metering of children's.
(3) therapeutic effect
Recovery from illness in slight jaundice 2-3 days, recovery from illness in middle icterus gravis 4-10 days.
Model case:
(1) female of Wu Mei group, 42 days, on January 28th, 2000, infant, after about 3rd day, was shown in that jaundice is not moved back, and more and more heavier, icteric sclera, whole body xanthochromia, companion's vomiting.Outpatient service jaundice color board surveys icteric index 250umol/L, and after treatment in 7 days, jaundice Periostracum Cicadae, only, things are as usual in vomiting.
(2) Deng Yinhua, man, 34 days, on December 22nd, 1999, infant is born second day certainly, icteric sclera, yellowish body, do not subtract through treatment, and symptom increases the weight of day by day, sometimes twinkles as seen, stare, feel suffocated obviously, day more than 10 times, by the agency of is sought medical advice, outpatient service jaundice color board 5 grades, icteric index 325umol/L, jaundice Periostracum Cicadae after treatment in 6 days, things are as usual.
(3) Zou Yiming, man, 2 days, on January 18th, 2009, first day of life was shown in the slight xanthochromia of sclera, within second day, find that xanthochromia obviously increases the weight of, women's head-ornaments breast abdomen extremity are all shown in middle severe xanthochromia, and laboratory audit report: Rh was positive on 19th, total bilirubin 276umol/L, unconjugated bilirubin 263umol/L, transaminase raises.Through 9 days medication treatments, jaundice Periostracum Cicadae, all were normal.
The present invention prepares simply, and curative effect is fast and stablize, without repeatedly having no side effect, safe and reliable, no matter light medium-deadly jauudice, all can fully recover in 2-10 days.
Detailed description of the invention
Embodiment 1:
Get Herba Artemisiae Scopariae 10g, Fructus Gardeniae 10g, Herba Abri 10g, Folium Isatidis 10g, Cortex Moutan 5g, Radix Gentianae 6g, Radix Curcumae 5g, Herba Hedyotidis Diffusae 10g, Fructus Aurantii Immaturus 5g, Radix Et Rhizoma Rhei 4g, Herba Patriniae 10g, Herba Lophatheri 10g, Radix Glycyrrhizae 5g, after above-mentioned raw materials is cleaned up, add the water soaking of 12 times of weight after two hours, after intense fire is boiled, change three times at a simmer into, first time decocts 1 hour, second time and third time decoct 40 minutes respectively, merge three times and decoct medicinal liquid, after being concentrated into paste, add dextrin, white sugar mix homogeneously, make granule with mesh screen and obtain product.
Usage and dosage; Every day 3 times, be grown up everyone each 15-20g, and children's measures everyone at every turn by per kilogram of body weight 0.5g.
Embodiment 2:
Get Herba Artemisiae Scopariae 15g, Fructus Gardeniae 15g, Herba Abri 15g, Folium Isatidis 15g, Cortex Moutan 10g, Radix Gentianae 10g, Radix Curcumae 10g, Herba Hedyotidis Diffusae 15g, Herba Patriniae 15g, Radix Et Rhizoma Rhei 6g, Radix Glycyrrhizae 10g, Herba Lophatheri 15g, Fructus Aurantii Immaturus 10g, after above-mentioned raw materials is cleaned up, add the water soaking of 12 times of weight after two hours, after intense fire is boiled, change three times at a simmer into, first time decocts 1 hour, second time and third time decoct 40 minutes respectively, merge three times and decoct medicinal liquid, after being concentrated into paste, add dextrin, white sugar mix homogeneously, make granule with mesh screen and obtain product.
Usage and dosage; Every day 3 times, be grown up everyone each 15-20g, and children's measures everyone at every turn by per kilogram of body weight 0.5g.
Embodiment 3:
Get Herba Artemisiae Scopariae 12g, Fructus Gardeniae 12g, Herba Abri 12g, Folium Isatidis 12g, Cortex Moutan 8g, Radix Gentianae 8g, Radix Curcumae 8g, Herba Hedyotidis Diffusae 12g, Herba Patriniae 12g, Radix Et Rhizoma Rhei 5g, Radix Glycyrrhizae 8g, Herba Lophatheri 12g, Fructus Aurantii Immaturus 8g, after above-mentioned raw materials is cleaned up, add the water soaking of 12 times of weight after two hours, after intense fire is boiled, change three times at a simmer into, first time decocts 1 hour, second time and third time decoct 40 minutes respectively, merge three times and decoct medicinal liquid, after being concentrated into paste, add dextrin, white sugar mix homogeneously, make granule with mesh screen and obtain product.
Usage and dosage; Every day 3 times, be grown up everyone each 15-20g, and children's measures everyone at every turn by per kilogram of body weight 0.5g.
Claims (4)
1. treat the Chinese medicinal granule of neonatal jaundice for one kind, it is characterized by, be made up of the raw material of following parts by weight: Herba Artemisiae Scopariae 10-15 part, Fructus Gardeniae 10-15 part, Herba Abri 10-15 part, Folium Isatidis 10-15 part, Cortex Moutan 5-10 part, Radix Gentianae 6-10 part, Radix Curcumae 5-10 part, Herba Hedyotidis Diffusae 10-15 part, Fructus Aurantii Immaturus 5-10 part, Radix Et Rhizoma Rhei 4-6 part, Herba Patriniae 10-15 part, Herba Lophatheri 10-15 part, Radix Glycyrrhizae 5-10 part.
2. the Chinese medicinal granule for the treatment of neonatal jaundice according to claim 1, it is characterized by, be made up of the raw material of following parts by weight: Herba Artemisiae Scopariae 12 parts, Fructus Gardeniae 12 parts, Herba Abri 12 parts, Folium Isatidis 12 parts, Cortex Moutan 8 parts, Radix Gentianae 8 parts, Radix Curcumae 8 parts, Herba Hedyotidis Diffusae 10 parts, Fructus Aurantii Immaturus 8 parts, Radix Et Rhizoma Rhei 5 parts, Herba Patriniae 12 parts, Herba Lophatheri 12 parts, 8 parts, Radix Glycyrrhizae.
3. the Chinese medicinal granule for the treatment of neonatal jaundice according to claim 1 and 2, it is characterized in that: described raw material is after cleaning up, add the water soaking of 12 times of weight after two hours, after intense fire is boiled, change three times at a simmer into, first time decocts 1 hour, second time and third time decoct 40 minutes respectively, merge three times and decoct medicinal liquid, after being concentrated into paste, add dextrin, white sugar mix homogeneously, make granule with mesh screen and obtain product.
4. the Chinese medicinal granule for the treatment of neonatal jaundice according to claim 3, is characterized in that: the weight ratio of described Chinese medicinal ointment, dextrin and white sugar is 1:1:1.5, and mesh screen is 40 order specifications, obtains product after granule dries.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232908A (en) * | 2015-11-17 | 2016-01-13 | 覃淑兰 | Traditional Chinese medicine granules for treating icterus and preparation method of traditional Chinese medicine granules |
| CN106139012A (en) * | 2016-07-29 | 2016-11-23 | 孙大宏 | A kind of enema treating neonatal jaundice |
| CN107753581A (en) * | 2017-10-27 | 2018-03-06 | 沈瑞金 | A kind of Chinese medicine for treating infantile jaundice |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1237425A (en) * | 1998-05-28 | 1999-12-08 | 邹鼎求 | Preparation method of liver-clearing jaundice-adating oral liquor |
| JP2013040143A (en) * | 2011-08-18 | 2013-02-28 | Saga Univ | Hepatic function disorder preventing/ameliorating agent |
-
2015
- 2015-08-14 CN CN201510496881.5A patent/CN105012485A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1237425A (en) * | 1998-05-28 | 1999-12-08 | 邹鼎求 | Preparation method of liver-clearing jaundice-adating oral liquor |
| JP2013040143A (en) * | 2011-08-18 | 2013-02-28 | Saga Univ | Hepatic function disorder preventing/ameliorating agent |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232908A (en) * | 2015-11-17 | 2016-01-13 | 覃淑兰 | Traditional Chinese medicine granules for treating icterus and preparation method of traditional Chinese medicine granules |
| CN106139012A (en) * | 2016-07-29 | 2016-11-23 | 孙大宏 | A kind of enema treating neonatal jaundice |
| CN107753581A (en) * | 2017-10-27 | 2018-03-06 | 沈瑞金 | A kind of Chinese medicine for treating infantile jaundice |
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Application publication date: 20151104 |