CN104984427B - A kind of hollow fiber membrane oxygenator with ultrafiltration apparatus - Google Patents
A kind of hollow fiber membrane oxygenator with ultrafiltration apparatus Download PDFInfo
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- CN104984427B CN104984427B CN201510409415.9A CN201510409415A CN104984427B CN 104984427 B CN104984427 B CN 104984427B CN 201510409415 A CN201510409415 A CN 201510409415A CN 104984427 B CN104984427 B CN 104984427B
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- ultrafilter
- blood
- ultrafiltration
- venous reservoir
- hollow fiber
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1698—Blood oxygenators with or without heat-exchangers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1629—Constructional aspects thereof with integral heat exchanger
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- Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- External Artificial Organs (AREA)
Abstract
The present invention relates to a kind of hollow fiber membrane oxygenator with ultrafiltration apparatus, including venous reservoir and oxygen to close heat-exchanging chamber, in addition to the ultrafilter inside venous reservoir；Ultrafilter blood entry port below ultrafilter closes heat-exchanging chamber with oxygen by blood vessel and connected；The upper side of ultrafilter is provided with the outlet of one or more ultrafilter blood；The lower side of ultrafilter is provided with ultrafiltrate outlet, ultrafiltrate outlet and venous reservoir ft connection.Oxygenator and ultrafilter are designed as integrated device by the present invention, only need to open during surgical staff use once to pack, it is installed on a support frame, ultrafiltration work can be carried out by opening ultrafiltration switch, reduce unnecessary attended operation, procedure efficiency is substantially increased, reduces the risk of maloperation, security reliability is high.
Description
Technical field
The present invention relates to a kind of hollow fiber membrane oxygenator with ultrafiltration apparatus.
Background technology
Membrane oxygenator is a kind of artificial organ that can carry out vim and vigour exchange, and it is according to the original of biological lung alveolar gas exchange
Reason, blood oxygenation removing carbon dioxide side by side is carried out for substituting human body PFT, is the essential doctor of cardiovascular surgical procedure
Treat equipment, and treatment acute respiratory illness and wait lung transplantation stage necessary Medical Devices.The membrane type of clinical practice at present
Oxygenator has the six functionses such as oxygen conjunction, heat exchange, storage blood, cardiotomy suction recovery, defoaming, filtering.It is on the books super in the world
Filter starts from nineteen twenty-eight, by regular Clinical practice since the sixties of twentieth century five.Common hyperfiltration process clinical now
There are conventional ultrafiltration, modified ultrafiltration, balance ultrafiltration etc., be that ultrafilter is connected in extracorporeal circulation pipeline, use ultrafilter
Main target is：Reduce the generation of the related capillary leak syndrome of inflammatory reaction；Mitigate water in Extracorporeal Circulation body
Adverse reaction caused by dividing increase；Reduce unnecessary blood transfusion；Moisture unnecessary in vivo is filtered out by blood circulation to protect to reach
Protect the function of internal organs.
Existing membrane oxygenator and ultrafilter have the disadvantage that：
1st, common membrane oxygenator and ultrafilter are two pieces device, and in surgical procedure, operating personnel need opening two
Secondary packaging, two supports of installation are supported, and need to be connected two devices with pipeline, whole process connecting link
More, complex operation, influences procedure efficiency；
2nd, common ultrafilter is without heat exchange function, even if used with membrane oxygenator, also inevitably in pipe simultaneously
Larger heat is lost in the running of road, influences surgical effect；
The content of the invention
It is an object of the present invention to provide a kind of hollow fiber membrane oxygenator with ultrafiltration apparatus, by ultrafilter and oxygenator
Integrated device is designed as, makes to install and use more safety convenient.
The present invention technical solution be：Hollow fiber membrane oxygenator provided by the invention with ultrafiltration apparatus, bag
Include venous reservoir and oxygen closes heat-exchanging chamber, it is characterized in that：Also include the ultrafilter inside venous reservoir；It is super
Blood entry port below filter closes heat-exchanging chamber with oxygen by blood vessel and connected；The upper side of ultrafilter be provided with one or
Multiple blood outlets；The lower side of ultrafilter is provided with ultrafiltrate outlet, ultrafiltrate outlet and venous reservoir ft connection.
Ultrafilter is integrally located inside venous reservoir, is improved the space availability ratio inside venous reservoir, is reduced medical worker
Installation attended operation, easy-to-use, good reliability.
The blood outlet of ultrafilter inside venous reservoir with connecting；The blood outlet is four, is symmetrically distributed in super
The upper side of filter.Multiple blood outlets can disperse blood flow well, avoid blood from impacting venous reservoir inwall.
Above-mentioned blood vessel switchs provided with ultrafiltration, can control work and the halted state of ultrafilter at any time.
Above-mentioned blood outlet is one, is connected with the venous drainage pipe outside venous reservoir.Above-mentioned blood vessel is provided with
Triple valve, three ports of the triple valve connect the blood entry port and arterial blood of oxygenation chamber blood outlet, ultrafilter respectively
Mouthful.Venous drainage pipe one end enters blood mouth with the vein of venous reservoir and connected, and provided with drainage switch.By arterial blood inlet with surpassing
When filter blood entry port turns on and closes drainage switch, working independently for ultrafilter can be achieved, ultrafiltration directly is carried out to arterial blood,
Occupation mode is flexible.
Blood pump can be also connected at arterial blood inlet and provides circulation power for arterial blood.
The top of above-mentioned ultrafilter is a round and smooth projection, can avoid blood when venous blood enters venous reservoir
Because excessively hit and caused by hematoclasis.
The advantage of the invention is that：
1st, oxygenator and ultrafilter are designed as integrated device by the present invention, are only needed to open during surgical staff use and are once wrapped
Dress, is installed on a support frame, and ultrafiltration work can be carried out by opening ultrafiltration switch, reduce unnecessary attended operation,
Procedure efficiency is substantially increased, reduces the risk of maloperation, security reliability is high.
2nd, the blood entry port of ultrafilter of the present invention is located at lower section, can be directly connected to, reduced by blood vessel and oxygenator
Exterior line, connected mode are easily achieved, and install and use facility.
3rd, the present invention connects a triple valve between ultrafilter and oxygenator, can be straight by the arterial blood inlet on triple valve
Connect and arterial blood is imported into ultrafilter progress ultrafiltration, the blood after ultrafiltration passes through a ultrafiltration blood outlet export again so that ultrafiltration
Device can also be used alone in addition to it can be used cooperatively with oxygenator, and occupation mode is more flexible.
4th, it is a round and smooth projection at the top of ultrafilter of the invention, can be avoided when venous blood enters venous reservoir
Blood because excessively hit and caused by hematoclasis.
5th, ultrafilter and oxygenator close installation are reduced transducer potector length, reduce thermal loss, carried by the present invention
High surgical effect.
6th, ultrafilter of the invention and oxygenator simple in construction, small volume, are produced, transported, made using same storage blood device
It is convenient and swift with process.
7th, ultrafilter of the invention is arranged on venous reservoir center, the space being effectively utilized inside venous reservoir,
It can try one's best simultaneously and the volume of ultrafilter is accomplished into maximum in venous reservoir, improve ultrafiltration effect.
Brief description of the drawings
Fig. 1 is the structural representation of the embodiment of the present invention one；
Fig. 2 is the structural representation of the embodiment of the present invention two.
Reference is as follows：1- venous reservoirs；2- oxygenation chambers；3- heat-exchanging chambers；4- ultrafilters；5- blood vessels；6- is quiet
Arteries and veins enters blood mouth；7- ultrafilter blood entry ports；8- ultrafilters blood exports；9- ultrafiltrates export；10- triple valves；11- oxygenation chambers go out
Blood mouth；12- arterial blood inlets；13- blood pumps；14- venous drainage pipes；15- is switched；At the top of 16- ultrafilters；17- ultrafiltration switchs；
18- reclaims blood collecting chamber；19- reclaims blood screen pack；20- recovery blood defoaming nets；21- recovery rooms；22- reclaims blood entrance；23- disappears
Indulge in serfing the Net；24- screen packs；25- storage blood room；26- phleborrhagia mouths；The standby blood sampling mouths of 27-；28- duty devices；29- doughnut oxygen
Close room；30- exhaust outlets；31- heat-exchanging chamber entrances；32- venous drainages enter blood mouth；The standby venous drainages of 33- enter blood mouth；34- points
Bleed entrance；35- filters preliminary filling mouth；36- quick pre-charging mouths；37- dosing mouths.
Embodiment
Referring to Fig. 1, the structure of the embodiment of the present invention one includes venous reservoir 1 and oxygen closes heat-exchanging chamber, wherein, top is
Venous reservoir 1, middle part are oxygenation chamber 2, and bottom is heat-exchanging chamber 3；Housing mainly uses clear hard non-toxic high molecular material,
Each connecting portion is clamping bonding form.
Venous reservoir 1 is internally provided with ultrafilter 4, and the ultrafilter blood entry port 7 of the lower section of ultrafilter 4 passes through blood vessel
5 close heat-exchanging chamber with oxygen connects；The upper side of ultrafilter 4 is provided with four ultrafilter blood outlets 8, to the blood after ultrafiltration
Shunting is realized, can effectively prevent hemodynamics excessive and percussion mechanism inwall；The lower side of ultrafilter 4 is provided with ultrafiltrate
Outlet 9, ultrafiltrate outlet 9 and venous reservoir ft connection.16 be one round and smooth prominent with certain radian at the top of ultrafilter
Rise, face vein enters blood mouth 6, can buffer the blood that top enters, reduce the excessive shock of blood, reduce and haemocyte is broken
It is bad.
Venous reservoir 1 is upright barrel-shaped axle heart-shaped structure, and its center is recovery blood collecting chamber 18, reclaims blood collecting chamber
Top passes sequentially through after the recovery blood screen pack 19 and recovery blood defoaming net 20 in outside and is provided with the recovery for reclaiming blood entrance 22
Room 21 is connected, and the bottom of recovery blood collecting chamber 18 is passed sequentially through after the defoaming net 23 and screen pack 24 in outside with being provided with phleborrhagia mouth
26 storage blood room 25 connects, and the bottom of storage blood room 25 is additionally provided with standby blood sampling mouth 27.The top cover of blood collecting chamber 18 is reclaimed provided with quiet
Arteries and veins drains enters blood mouth 33, shunting blood entrance 34, quick pre-charging mouth 36 and dosing mouth 37 into blood mouth 32, standby venous drainage.Recovery
The top of room 21 is provided with filtering preliminary filling mouth 35.
Oxygenation chamber 2 is located at the lower section of venous reservoir 1, is also upright barrel-shaped axle heart-shaped structure, oxygenation chamber center is duty
Device 28, duty device outside is doughnut oxygenation chamber 29, and oxygenation chamber bottom is provided with exhaust outlet 30；Doughnut oxygenation chamber passes through oxygen
Chamber inlet is closed to connect with underlying heat-exchanging chamber 3；The bottom of heat-exchanging chamber 3 is provided with heat-exchanging chamber entrance 31, in heat-exchanging chamber 3
Provided with some horizontally arranged heat-exchange tubes, the water inlet and delivery port of heat-exchange tube are located at the outside of heat-exchanging chamber.
In use, the superior and inferior vena cava blood of patient enters blood mouth 6 by vein enters venous reservoir 1, blood passes through ultrafilter
The round and smooth projection at top can obtain certain buffering, and the destruction to haemocyte is hit when reducing direct whereabouts.Blood passes through
Exported by venous reservoir after defoaming filtering, after passing sequentially through heat-exchanging chamber 3 and oxygenation chamber 2, then entered by blood through blood vessel 5
Mouth 7 starts ultrafiltration into ultrafilter.Blood after ultrafiltration is store by entering vein after the shunting of four blood outlet 8 above ultrafilter
Blood room 1, ultrafiltrate caused by ultrafiltration are discharged outside venous reservoir by the ultrafiltrate outlet 9 of ultrafilter lower side.
Referring to Fig. 2, the structure of the embodiment of the present invention two is provided with triple valve 10 on blood vessel 5, three of triple valve 10
Port connects with oxygenation chamber blood outlet 11, the blood entry port 7 of ultrafilter and arterial blood inlet 12 respectively.The blood of ultrafilter goes out
Mouth 8 is one, is connected with the venous drainage pipe 14 outside venous reservoir, the one end of venous drainage pipe 14 enters blood mouth 6 with vein and connected
It is logical, it is provided with switch 15.Other parts are identical with the structure of the embodiment of the present invention one.When the switch of control triple valve 10 makes
When the blood entry port 7 of oxygenation chamber blood outlet 11 and ultrafilter turns on and opens switch 15, it can be achieved normal with the identical of embodiment one
Advise ultrafiltration function.When the switch of control triple valve 10 makes the blood entry port 7 of arterial blood inlet 12 and ultrafilter turn on and close out
When closing 15, modified ultrafiltration function can be achieved：Arterial blood introducing ultrafilter 4 is started into ultrafiltration, the blood after ultrafiltration is by ultrafilter
Blood outlet 8 enters patient's body after exporting to venous drainage pipe 14.Arterial blood inlet 12 can also connect a blood pump 13 with
Improve the circulation power of arterial blood.
Claims (9)
1. a kind of hollow fiber membrane oxygenator with ultrafiltration apparatus, including venous reservoir and oxygen close heat-exchanging chamber, its feature
It is：Also include the ultrafilter inside venous reservoir；Ultrafilter blood entry port below the ultrafilter passes through bloody path
Pipe closes heat-exchanging chamber with oxygen and connected；The upper side of ultrafilter is provided with the outlet of one or more ultrafilter blood；Ultrafilter
Lower side be provided with ultrafiltrate outlet, ultrafiltrate outlet with venous reservoir ft connection；The top of the ultrafilter is
One round and smooth projection with radian, the vein of the round and smooth projection face venous reservoir enter blood mouth.
2. the hollow fiber membrane oxygenator according to claim 1 with ultrafiltration apparatus, it is characterised in that：Ultrafilter blood
Outlet inside venous reservoir with connecting；The ultrafilter blood outlet is four, is symmetrically distributed in the upper side of ultrafilter.
3. the hollow fiber membrane oxygenator according to claim 2 with ultrafiltration apparatus, it is characterised in that：The blood vessel
Ultrafiltration is provided with to switch.
4. the hollow fiber membrane oxygenator according to claim 1 with ultrafiltration apparatus, it is characterised in that：The ultrafilter
Blood outlet is one, is connected with the venous drainage pipe outside venous reservoir.
5. the hollow fiber membrane oxygenator according to claim 4 with ultrafiltration apparatus, it is characterised in that：The vein draws
Flow tube one end enters blood mouth with the vein of venous reservoir and connected, and provided with switch.
6. the hollow fiber membrane oxygenator according to claim 5 with ultrafiltration apparatus, it is characterised in that：The blood vessel
Ultrafiltration is provided with to switch.
7. the hollow fiber membrane oxygenator according to claim 6 with ultrafiltration apparatus, it is characterised in that：The ultrafiltration is opened
Close and connect oxygenation chamber blood outlet, ultrafilter blood entry port and artery respectively for triple valve, three ports of the triple valve and enter
Blood mouth.
8. the hollow fiber membrane oxygenator according to claim 7 with ultrafiltration apparatus, it is characterised in that：The artery enters
Blood mouth is connected with blood pump.
9. according to any described hollow fiber membrane oxygenator with ultrafiltration apparatus in claim 1-8, it is characterised in that：Institute
It is upright barrel-shaped structure to state venous reservoir, and the ultrafilter is located at venous reservoir center or inwall side.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510409415.9A CN104984427B (en) | 2015-07-13 | 2015-07-13 | A kind of hollow fiber membrane oxygenator with ultrafiltration apparatus |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510409415.9A CN104984427B (en) | 2015-07-13 | 2015-07-13 | A kind of hollow fiber membrane oxygenator with ultrafiltration apparatus |
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| CN104984427A CN104984427A (en) | 2015-10-21 |
| CN104984427B true CN104984427B (en) | 2017-11-17 |
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| CN201510409415.9A Active CN104984427B (en) | 2015-07-13 | 2015-07-13 | A kind of hollow fiber membrane oxygenator with ultrafiltration apparatus |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113398354B9 (en) * | 2021-07-14 | 2022-05-03 | 江苏赛腾医疗科技有限公司 | Integrated membrane oxygenator |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4902476A (en) * | 1983-01-14 | 1990-02-20 | Baxter International Inc. | Heat exchanger and blood oxygenator apparatus |
| EP0371173A1 (en) * | 1988-11-03 | 1990-06-06 | BAXTER INTERNATIONAL INC. (a Delaware corporation) | Integral blood defoamer, reservoir, heat exchanger, and cardiotomy filter |
| CN2137528Y (en) * | 1992-08-10 | 1993-07-07 | 戴刚 | Bubbling type oxygenator with intracordial blood-suction-storage device |
| CN2647323Y (en) * | 2003-08-20 | 2004-10-13 | 戴刚 | Non-pump driving external oxygenation supporting treatment hollow fiber membrane oxygenator |
| ITFI20030256A1 (en) * | 2003-10-09 | 2005-04-10 | Angela Caramuta | DEVICE FOR THE ELIMINATION OF CARBON DIOXIDE |
| CN201220008Y (en) * | 2007-12-10 | 2009-04-15 | 西安西京医疗用品有限公司 | Integral membrane oxygenator |
| CN204815054U (en) * | 2015-07-13 | 2015-12-02 | 西安岱岱生物医学工程有限责任公司 | Take ultrafiltration device's hollow fiber membrane formula oxygenator |
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Effective date of registration: 20190613 Address after: 710065 Room A508, Xijing International Electric Center, No. 3 Electronic West Street, Yanta District, Xi'an City, Shaanxi Province Patentee after: Xi'an Daidai Shengmei Biotechnology Co., Ltd. Address before: 710065 No. 3 Electronic West Street, Xi'an City, Shaanxi Province Patentee before: Xi'an Dai Dai biomedical engineering Co., Ltd |
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