CN104984427A - Hollow fiber membrane type oxygenator with ultrafiltration device - Google Patents
Hollow fiber membrane type oxygenator with ultrafiltration device Download PDFInfo
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- CN104984427A CN104984427A CN201510409415.9A CN201510409415A CN104984427A CN 104984427 A CN104984427 A CN 104984427A CN 201510409415 A CN201510409415 A CN 201510409415A CN 104984427 A CN104984427 A CN 104984427A
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- ultrafilter
- blood
- fiber membrane
- hollow
- ultrafiltration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1698—Blood oxygenators with or without heat-exchangers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1629—Constructional aspects thereof with integral heat exchanger
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- Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- External Artificial Organs (AREA)
Abstract
The invention relates to a hollow fiber membrane type oxygenator with an ultrafiltration device. The hollow fiber membrane type oxygenator with the ultrafiltration device comprises a vein blood storage chamber and an oxygenation heat exchange chamber and further comprises an ultrafilter which is located inside the vein blood storage chamber. An ultrafilter blood inlet below the ultrafilter is communicated with the oxygenation heat exchange chamber through a blood pipeline. One or more ultrafilter blood outlets are formed in the side face of the upper portion of the ultrafilter. An ultrafiltrate outlet is formed in the side face of the lower portion of the ultrafilter. The ultrafiltrate outlet is communicated with the outside of the vein blood storage chamber. According to the hollow fiber membrane type oxygenator with the ultrafiltration device, the oxygenator and the ultrafilter are designed into an integral device; when the hollow fiber membrane type oxygenator is used, a surgical operator just needs to open a disposable package and then install the hollow fiber membrane type oxygenator on a supporting frame, ultrafiltration work can be conducted simply by turning on an ultrafiltration switch, in this way, redundant connection operation is reduced, operation efficiency is greatly improved, the risk of misoperation is lowered, and both the safety performance and the reliability are high.
Description
Technical field
The present invention relates to a kind of hollow-fiber membrane oxygenator with ultrafiltration apparatus.
Background technology
Membrane oxygenator is a kind of artificial organ that can carry out vim and vigour exchange, it is according to the principle of biological lung alveolar gas exchange, blood oxygenation removing carbon dioxide is side by side carried out for alternative Human Lung function, being the requisite armarium of cardiovascular surgical procedure, is also treat acute respiratory illness and wait for the armarium that the lung transplantation stage is necessary.The membrane oxygenator of current clinical practice has the six functionses such as oxygenate, heat exchange, storage blood, cardiotomy suction recovery, froth breaking, filtration.Ultrafilter on the books in the world starts from nineteen twenty-eight, by regular Clinical practice from twentieth century five sixties.Clinical common hyperfiltration process has conventional ultrafiltration, modified ultrafiltration, balance ultrafiltration etc. now, is all be connected in extracorporeal circulation pipeline by ultrafilter, and the main target of use ultrafilter is: the generation reducing the capillary leak syndrome that inflammatory reaction is correlated with; The untoward reaction that in ameliorate body outer circulation postoperative body, moisture increase causes; Reduce unnecessary blood transfusion; Moisture unnecessary in body is leached to reach the function of protection internal organs by blood circulation.
There is following shortcoming in existing membrane oxygenator and ultrafilter:
1, common membrane oxygenator and ultrafilter are two pieces device, and in operation process, operator need to open twice packaging, two supports are installed support, and need to be coupled together by two devices with pipeline, whole process connecting link is many, complicated operation, affects procedure efficiency;
2, common ultrafilter is not with hot-swap feature, even if use with membrane oxygenator simultaneously, also inevitably in pipeline running, loses larger heat, affects surgical effect;
Summary of the invention
The object of the invention is to provide a kind of hollow-fiber membrane oxygenator with ultrafiltration apparatus, and ultrafilter and oxygenator are designed to integrated device, makes to install and use safety convenient more.
Technical solution of the present invention is: the hollow-fiber membrane oxygenator of band ultrafiltration apparatus provided by the invention, and comprise venous reservoir and oxygenate heat-exchanging chamber, its special character is: also comprise the ultrafilter being positioned at venous reservoir inside; Blood entry port below ultrafilter is communicated with oxygenate heat-exchanging chamber by blood vessel; The upper side of ultrafilter is provided with the outlet of one or more blood; The lower side of ultrafilter is provided with ultrafiltrate outlet, ultrafiltrate outlet and venous reservoir ft connection.Ultrafilter entirety is positioned at venous reservoir inside, improves the space availability ratio of venous reservoir inside, decreases the installation attended operation of medical worker, easy-to-use, good reliability.
The blood outlet of ultrafilter is communicated with venous reservoir inside; Described blood outlet is four, and symmetry is distributed in the upper side of ultrafilter.Multiple blood outlet can disperse blood flow well, avoids blood to impact venous reservoir inwall.
Above-mentioned blood vessel is provided with ultrafiltration switch, can control work and the halted state of ultrafilter at any time.
Above-mentioned blood outlet is one, is communicated with the venous drainage pipe of venous reservoir outside.Above-mentioned blood vessel is provided with three-way valve, and three ports of described three-way valve connect oxygenation chamber blood outlet, the blood entry port of ultrafilter and arterial blood inlet respectively.Venous drainage pipe one end and the vein of venous reservoir enter blood mouth and are communicated with, and are provided with drain switch.Arterial blood inlet and the conducting of ultrafilter blood entry port, when closing drain switch, can be realized working independently of ultrafilter, and directly carry out ultrafiltration to arterial blood, occupation mode is flexible.
Arterial blood inlet place also can connect blood pump for arterial blood provides circulation power.
The top of above-mentioned ultrafilter is a round and smooth projection, blood can be avoided to cause hematoclasis because excessively clashing into when venous blood enters venous reservoir.
The invention has the advantages that:
1, oxygenator and ultrafilter are designed to integrated device by the present invention, surgical staff only needs to open once to pack when using, be installed on a bracing frame, open ultrafiltration switch and just can carry out ultrafiltration work, decrease unnecessary attended operation, substantially increase procedure efficiency, reduce the risk of maloperation, security reliability is high.
2, the blood entry port of ultrafilter of the present invention is positioned at below, is directly connected, decreases exterior line by blood vessel with oxygenator, and connected mode is easy to realize, and installs and uses facility.
3, the present invention is connected a three-way valve between ultrafilter with oxygenator, directly arterial blood can be imported ultrafilter by the arterial blood inlet on three-way valve and carry out ultrafiltration, blood after ultrafiltration is derived by a ultrafiltration blood outlet again, make ultrafilter except can with oxygenator with the use of except also can be used alone, occupation mode is more flexible.
4, ultrafilter top of the present invention is a round and smooth projection, blood can be avoided to cause hematoclasis because excessively clashing into when venous blood enters venous reservoir.
5, the present invention is by ultrafilter and oxygenator close installation, reduces transducer potector length, decreases thermal loss, improve surgical effect.
6, ultrafilter of the present invention and oxygenator use same storage blood device, and structure is simple, and volume is little, produce, transport, use procedure be all convenient and swift.
7, ultrafilter of the present invention is arranged on venous reservoir center, effectively make use of the space of venous reservoir inside, can accomplish maximum by the volume of ultrafilter in venous reservoir simultaneously as far as possible, improves ultrafiltration effect.
Accompanying drawing explanation
Fig. 1 is the structural representation of the embodiment of the present invention one;
Fig. 2 is the structural representation of the embodiment of the present invention two.
Reference numeral is as follows: 1-venous reservoir; 2-oxygenation chamber; 3-heat-exchanging chamber; 4-ultrafilter; 5-blood vessel; 6-vein enters blood mouth; 7-ultrafilter blood entry port; 8-ultrafilter blood exports; 9-ultrafiltrate exports; 10-three-way valve; 11-oxygenation chamber blood outlet; 12-arterial blood inlet; 13-blood pump; 14-venous drainage pipe; 15-switch; 16-ultrafilter top; 17-ultrafiltration switch; 18-reclaims blood collecting chamber; 19-reclaims blood drainage screen; 20-reclaims blood froth breaking net; 21-reclaims room; 22-reclaims blood entrance; 23-froth breaking net; 24-drainage screen; 25-stores blood room; 26-venous hemorrhage mouth; 27-blood sampling mouth for subsequent use; 28-duty device; 29-doughnut oxygenation chamber; 30-air vent; 31-heat-exchanging chamber entrance; 32-venous drainage enters blood mouth; 33-venous drainage for subsequent use enters blood mouth; 34-divides entrance of bleeding; 35-filters preliminary filling mouth; 36-quick pre-charging mouth; 37-dosing mouth.
Detailed description of the invention
See Fig. 1, the structure of the embodiment of the present invention one comprises venous reservoir 1 and oxygenate heat-exchanging chamber, and wherein, top is venous reservoir 1, and middle part is oxygenation chamber 2, and bottom is heat-exchanging chamber 3; Housing mainly adopts clear hard non-toxic high molecular material, and each connecting portion is the bonding form of clamping.
The inside of venous reservoir 1 is provided with ultrafilter 4, and the ultrafilter blood entry port 7 below ultrafilter 4 is communicated with oxygenate heat-exchanging chamber by blood vessel 5; The upper side of ultrafilter 4 is provided with four ultrafilter blood outlets 8, realizes shunting, can effectively prevent hemodynamics excessive and percussion mechanism inwall to the blood after ultrafiltration; The lower side of ultrafilter 4 is provided with ultrafiltrate outlet 9, ultrafiltrate outlet 9 and venous reservoir ft connection.Ultrafilter top 16 is a round and smooth projection with certain radian, just enters blood mouth 6 to vein, can cushion the blood that top enters, and reduces the excessive shock of blood, reduces the destruction to hemocyte.
Venous reservoir 1 is upright barrel-shaped axle heart-shaped structure, its center is for reclaiming blood collecting chamber 18, reclaim blood collecting chamber top successively by the recovery blood drainage screen 19 in outside and reclaim blood froth breaking net 20 afterwards be provided with the recovery room 21 of reclaiming blood entrance 22 and be communicated with, reclaim blood collecting chamber 18 bottom to be communicated with the storage blood room 25 being provided with venous hemorrhage mouth 26 with drainage screen 24 is rear by the froth breaking net 23 in outside successively, storage bottom, blood room 25 is also provided with blood sampling mouth 27 for subsequent use.The top cover reclaiming blood collecting chamber 18 is provided with that venous drainage enters blood mouth 32, venous drainage for subsequent use enters blood mouth 33, point to bleed entrance 34, quick pre-charging mouth 36 and dosing mouth 37.The top of reclaiming room 21 is provided with filters preliminary filling mouth 35.
Oxygenation chamber 2 is positioned at below venous reservoir 1, and be also upright barrel-shaped axle heart-shaped structure, oxygenation chamber center is duty device 28, and be doughnut oxygenation chamber 29 outside duty device, oxygenation chamber bottom is provided with air vent 30; Doughnut oxygenation chamber is communicated with the heat-exchanging chamber 3 being positioned at below by oxygenation chamber entrance; Be provided with heat-exchanging chamber entrance 31 bottom heat-exchanging chamber 3, be provided with some horizontal heat-exchange tubes in heat-exchanging chamber 3, the water inlet of heat-exchange tube and outlet are positioned at the outside of heat-exchanging chamber.
During use, the superior and inferior vena cava blood of patient enters blood mouth 6 by vein and enters venous reservoir 1, and blood can obtain certain buffering by the round and smooth projection at ultrafilter top, decreases the destruction of shock to hemocyte when directly falling.Blood is derived by venous reservoir after froth breaking filters, and successively by after heat-exchanging chamber 3 and oxygenation chamber 2, then enters ultrafilter through blood vessel 5 by blood entry port 7 and starts ultrafiltration.Blood after ultrafiltration by the blood of four above ultrafilter export 8 shuntings laggard enter venous reservoir 1, the ultrafiltrate that ultrafiltration produces exports 9 by the ultrafiltrate of ultrafilter lower side and discharges outside venous reservoirs.
See Fig. 2, the structure of the embodiment of the present invention two is provided with three-way valve 10 on blood vessel 5, and three ports of three-way valve 10 are communicated with the blood entry port 7 of oxygenation chamber blood outlet 11, ultrafilter and arterial blood inlet 12 respectively.The blood outlet 8 of ultrafilter is one, and be communicated with the venous drainage pipe 14 of venous reservoir outside, venous drainage pipe 14 one end and vein enter blood mouth 6 and be communicated with, and are provided with switch 15.Other parts are identical with the structure of the embodiment of the present invention one.When the switch controlling three-way valve 10 makes blood entry port 7 conducting of oxygenation chamber blood outlet 11 and ultrafilter and opens switch 15, the conventional ultrafiltration function identical with embodiment one can be realized.When control the switch of three-way valve 10 and make blood entry port 7 conducting of arterial blood inlet 12 and ultrafilter and closing switch 15 time, can realize modified ultrafiltration function: arterial blood is introduced ultrafilter 4 and start ultrafiltration, the blood after ultrafiltration enters in patient body after exporting to venous drainage pipe 14 by the blood outlet 8 of ultrafilter.Arterial blood inlet 12 can also connect a blood pump 13 to improve the circulation power of arterial blood.
Claims (10)
1. the hollow-fiber membrane oxygenator with ultrafiltration apparatus, comprises venous reservoir and oxygenate heat-exchanging chamber, it is characterized in that: also comprise the ultrafilter being positioned at venous reservoir inside; Ultrafilter blood entry port below described ultrafilter is communicated with oxygenate heat-exchanging chamber by blood vessel; The upper side of ultrafilter is provided with the outlet of one or more ultrafilter blood; The lower side of ultrafilter is provided with ultrafiltrate outlet, ultrafiltrate outlet and venous reservoir ft connection.
2. the hollow-fiber membrane oxygenator of band ultrafiltration apparatus according to claim 1, is characterized in that: the outlet of ultrafilter blood is communicated with venous reservoir inside; Described ultrafilter blood outlet is four, and symmetry is distributed in the upper side of ultrafilter.
3. the hollow-fiber membrane oxygenator of band ultrafiltration apparatus according to claim 2, is characterized in that: described blood vessel is provided with ultrafiltration switch.
4. the hollow-fiber membrane oxygenator of band ultrafiltration apparatus according to claim 1, is characterized in that: described ultrafilter blood outlet is one, is communicated with the venous drainage pipe of venous reservoir outside.
5. the hollow-fiber membrane oxygenator of band ultrafiltration apparatus according to claim 4, is characterized in that: described venous drainage pipe one end enters blood mouth with the vein of venous reservoir and is communicated with, and is provided with switch.
6. the hollow-fiber membrane oxygenator of band ultrafiltration apparatus according to claim 5, is characterized in that: described blood vessel is provided with ultrafiltration switch.
7. the hollow-fiber membrane oxygenator of band ultrafiltration apparatus according to claim 6, is characterized in that: described ultrafiltration switch is three-way valve, and three ports of described three-way valve connect oxygenation chamber blood outlet, ultrafilter blood entry port and arterial blood inlet respectively.
8. the hollow-fiber membrane oxygenator of band ultrafiltration apparatus according to claim 7, is characterized in that: described arterial blood inlet is connected with blood pump.
9. according to the hollow-fiber membrane oxygenator of described band ultrafiltration apparatus arbitrary in claim 1 ~ 8, it is characterized in that: the top of described ultrafilter is a round and smooth projection.
10. the hollow-fiber membrane oxygenator of band ultrafiltration apparatus according to claim 9, is characterized in that: described venous reservoir is upright barrel-shaped structure, and described ultrafilter is positioned at venous reservoir center or inwall side.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510409415.9A CN104984427B (en) | 2015-07-13 | 2015-07-13 | A kind of hollow fiber membrane oxygenator with ultrafiltration apparatus |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510409415.9A CN104984427B (en) | 2015-07-13 | 2015-07-13 | A kind of hollow fiber membrane oxygenator with ultrafiltration apparatus |
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| CN104984427A true CN104984427A (en) | 2015-10-21 |
| CN104984427B CN104984427B (en) | 2017-11-17 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113398354A (en) * | 2021-07-14 | 2021-09-17 | 江苏赛腾医疗科技有限公司 | Integrated membrane oxygenator |
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| US4902476A (en) * | 1983-01-14 | 1990-02-20 | Baxter International Inc. | Heat exchanger and blood oxygenator apparatus |
| EP0371173A1 (en) * | 1988-11-03 | 1990-06-06 | BAXTER INTERNATIONAL INC. (a Delaware corporation) | Integral blood defoamer, reservoir, heat exchanger, and cardiotomy filter |
| CN2137528Y (en) * | 1992-08-10 | 1993-07-07 | 戴刚 | Bubbling type oxygenator with intracordial blood-suction-storage device |
| CN2647323Y (en) * | 2003-08-20 | 2004-10-13 | 戴刚 | Non-pump driving external oxygenation supporting treatment hollow fiber membrane oxygenator |
| EP1522323A1 (en) * | 2003-10-09 | 2005-04-13 | Medical Service S.r.l. | Device for eliminating carbon dioxide from the blood and a crrt apparatus provided with said device |
| CN201220008Y (en) * | 2007-12-10 | 2009-04-15 | 西安西京医疗用品有限公司 | Integral membrane oxygenator |
| CN204815054U (en) * | 2015-07-13 | 2015-12-02 | 西安岱岱生物医学工程有限责任公司 | Take ultrafiltration device's hollow fiber membrane formula oxygenator |
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2015
- 2015-07-13 CN CN201510409415.9A patent/CN104984427B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4902476A (en) * | 1983-01-14 | 1990-02-20 | Baxter International Inc. | Heat exchanger and blood oxygenator apparatus |
| EP0371173A1 (en) * | 1988-11-03 | 1990-06-06 | BAXTER INTERNATIONAL INC. (a Delaware corporation) | Integral blood defoamer, reservoir, heat exchanger, and cardiotomy filter |
| CN2137528Y (en) * | 1992-08-10 | 1993-07-07 | 戴刚 | Bubbling type oxygenator with intracordial blood-suction-storage device |
| CN2647323Y (en) * | 2003-08-20 | 2004-10-13 | 戴刚 | Non-pump driving external oxygenation supporting treatment hollow fiber membrane oxygenator |
| EP1522323A1 (en) * | 2003-10-09 | 2005-04-13 | Medical Service S.r.l. | Device for eliminating carbon dioxide from the blood and a crrt apparatus provided with said device |
| CN201220008Y (en) * | 2007-12-10 | 2009-04-15 | 西安西京医疗用品有限公司 | Integral membrane oxygenator |
| CN204815054U (en) * | 2015-07-13 | 2015-12-02 | 西安岱岱生物医学工程有限责任公司 | Take ultrafiltration device's hollow fiber membrane formula oxygenator |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113398354A (en) * | 2021-07-14 | 2021-09-17 | 江苏赛腾医疗科技有限公司 | Integrated membrane oxygenator |
| CN113398354B (en) * | 2021-07-14 | 2022-02-22 | 江苏赛腾医疗科技有限公司 | Integrated membrane oxygenator |
| CN113398354B9 (en) * | 2021-07-14 | 2022-05-03 | 江苏赛腾医疗科技有限公司 | Integrated membrane oxygenator |
| US11730870B2 (en) | 2021-07-14 | 2023-08-22 | Jiangsu Stmed Technology Co., Ltd. | Integrated membrane oxygenators |
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| CN104984427B (en) | 2017-11-17 |
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Effective date of registration: 20190613 Address after: 710065 Room A508, Xijing International Electric Center, No. 3 Electronic West Street, Yanta District, Xi'an City, Shaanxi Province Patentee after: Xi'an Daidai Shengmei Biotechnology Co., Ltd. Address before: 710065 No. 3 Electronic West Street, Xi'an City, Shaanxi Province Patentee before: Xi'an Dai Dai biomedical engineering Co., Ltd |