CN206792725U - A kind of right heart shunt pump - Google Patents

A kind of right heart shunt pump Download PDF

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Publication number
CN206792725U
CN206792725U CN201621051107.XU CN201621051107U CN206792725U CN 206792725 U CN206792725 U CN 206792725U CN 201621051107 U CN201621051107 U CN 201621051107U CN 206792725 U CN206792725 U CN 206792725U
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China
Prior art keywords
blood
unidirectional valve
right heart
end unidirectional
valve
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Expired - Fee Related
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CN201621051107.XU
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Chinese (zh)
Inventor
王振华
薛松
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Renji Hospital Shanghai Jiaotong University School of Medicine
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Renji Hospital Shanghai Jiaotong University School of Medicine
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Abstract

The utility model provides a kind of right heart shunt pump, it is characterized in that, the blood shunting device that pulmonary artery simultaneously and then out of storage blood device is flowed into blood device is stored up including the storage blood device that can be connected respectively with vena cave and pulmonary artery, and for driving blood to be flowed into from vena cave.The pump energy effective drainage goes out superior and inferior vena cava blood, then is pumped into pulmonary artery, so as to provide visual operation open country for right heart system operation.Changing part of heart surgical operation needs the present situation of extracorporal circulatory system.The turn of tidal stream pump can provide pulsation blood flow, the protection heart, lung etc. easily by ischemical reperfusion injury organ simultaneously, reduce body inflammatory factor activator, more meet physiology.In addition right heart auxiliary pump is alternatively arranged as, the treatment for clinical right heart failure patient.Right heart shunt pump is simple to operate, dependable performance, and new therapy approach is provided for the treatment of cardiac.

Description

A kind of right heart shunt pump
Technical field
A kind of medical instruments field is the utility model is related to, belongs to cardiovascular injuries surgical field.
Background technology
First cardiopulmonary bypass system is to be invented by John Heysham Gibbon in nineteen thirty-seven in the world, by a system Row improve, and are successfully applied to body operation for the first time with nineteen fifty-three.Extracorporal circulatory system provides a stabilization, no blood for openheart surgery Operating environment while, itself can also cause a series of side effect.After in blood lead body, circulating pipe system can activate Various visible components in blood, except causing Coagulation Dysfunction, also result in various ischemical reperfusion injuries and endotoxin Release.These visible components include fibrin ferment, kinases, fibrinolysin, leucocyte, blood platelet, inflammatory factor etc..They are led Injury response the lighter of cause is as generated heat, tissue edema, and severe one causes acute organ dysfunction even dead.
In order to reduce the various side reactions of extracorporal circulatory system, researcher has attempted various possible schemes.As added heparin to apply in pipeline Layer is to increase biocompatibility;Duct length is reduced as far as possible even without extracorporal circulatory system, such as off-pump bypass;Enable Centrifugal pump come reduce vim and vigour contact and Blood damage;Using steroids or nonsteroidal anti-inflammatory drug, protease inhibitors, antioxygen Agent, antifibrinolytic agent etc..Experiment shows, relative to conventional impeller pump and common pipeline, the extracorporeal circulation system of closing and Centrifugal pump turn of tidal stream can be substantially reduced the inflammatory reaction of patient's body, suppress the activation of various protease, thus significantly improve trouble Person's perioperative is survived.Overwhelming majority operation at present still relies on extracorporal circulatory system, it is necessary to be completed under cardiac arrest state.Internal organs lack Blood and functional lesion are inevitable.Centrifugal pump and the circulation line high cost with heparin coating, clinical practice are also difficult to push away Extensively.
The content of the invention
The purpose of this utility model is to provide a kind of new right heart shunt pump, and the pump energy effective drainage goes out superior and inferior vena cava Blood, then pulmonary artery is pumped into, so as to provide visual operation open country for right heart system operation.
In order to achieve the above object, the utility model provides a kind of right heart shunt pump, it is characterised in that including that can divide The storage blood device not being connected with vena cave and pulmonary artery, and for driving blood to be flowed into from vena cave in storage blood device and from storage The blood shunting device of pulmonary artery is flowed into blood device.
Preferably, described storage blood device has into blood mouth and blood outlet, described to enter blood mouth and blood outlet is respectively equipped with The vein end pipe joint that can be connected with vena cave and the arterial end pipe joint that can be connected with pulmonary artery.
It is highly preferred that described vein end pipe joint and arterial end pipe joint passes through pipeline and vena cave and lung respectively Artery connects, and described pipeline is heart cathetrization, artificial blood vessel or the combination of the two.
It is highly preferred that described blood shunting device includes vein end unidirectional valve and arterial end unidirectional valve, described vein End unidirectional valve and arterial end unidirectional valve are respectively arranged on the entering in blood mouth and blood outlet of described storage blood device, and vein end is unidirectional The opening direction of flap valve is towards inside storage blood device, and when vein end unidirectional valve is opened, described vena cave is with storing up blood dress Connect between putting, when vein end unidirectional valve is closed, do not connected between described vena cave and storage blood device, described artery The opening direction for holding unidirectional valve is towards housing exterior, when arterial end unidirectional valve is opened, described pulmonary artery and storage blood Connect between device, when arterial end unidirectional valve is closed, do not connected between described pulmonary artery and storage blood device;Described turns Stream device also includes being used for the drive device for driving vein end unidirectional valve and arterial end unidirectional valve to open and close.
It is highly preferred that described storage blood device includes shell, described shell is tubulose, including main line and branch pipe The middle part of road, the described both ends for entering blood mouth and blood outlet and being located at main line respectively, described bye-pass and main line connects, institute The drive device for being used to drive vein end unidirectional valve and arterial end unidirectional valve to open and close stated includes piston, described Piston is located in described bye-pass, and when piston inwardly moves, vein end unidirectional valve is closed, and arterial end unidirectional valve is opened Open, when piston moves out, vein end unidirectional valve is opened, and arterial end unidirectional valve is closed.
It is highly preferred that described main line and bye-pass is all cylindrical structure, the two combines T-shaped or Y-shaped structure.
It is highly preferred that described shell and piston are used in rubber, lucite, glass, plastics or metal material extremely Few one kind is made.
It is highly preferred that described enclosure capacity is 20ml-300ml.
It is highly preferred that described piston is driven using power set.
It is highly preferred that described power set are motor.
It is highly preferred that described vein end unidirectional valve is artificial valve, biovalve or one way stop peturn valve.
It is highly preferred that described arterial end unidirectional valve is artificial valve, biovalve or one way stop peturn valve.
Compared with prior art, the beneficial effects of the utility model are:
1st, compared with existing cardiopulmonary bypass unit, structure simplifies the utility model, simple to operate, securely and reliably, is produced into This is low.When completing right heart system operation, extracorporal circulatory system and total body hypothermia process are avoided, reduces immune system and blood coagulation The activation of system, reduce the ischemical reperfusion injury of Blood damage and body.The utility model can provide pulsation blood flow, protect Shield heart, lung etc. easily by ischemical reperfusion injury organ, reduce body inflammatory factor activator, more meet physiology, avoid pulmonary ventilation blood Stream is advantageous to the recovery of postoperative patient PFT than imbalance.In addition, for the patient of right heart failure, heart assistance is also used as Device carries out prolonged external or the right heart aids in vivo.The advantages of these are all not available for conventional rotors cardiopulmonary bypass unit.
2nd, the utility model is only in patient's superior and inferior vena cava and pulmonary arterial catheter, and superior and inferior vena cava blood flow is through pipeline liquid injecting device pump Enter pulmonary artery, system conveying whole body is felt concerned about by a left side for autologous patient again after the conjunction of intrapulmonary oxygen.This turn of tidal stream mode can expose the right side Room and right ventricle, the operation that system is felt concerned about for the right side create condition.Atrial septal defect, right room occupy-place, tricuspid insufficiency, The disease such as Ebstein deformities and stenosis of right ventricular outflow tract can be in the state of heart beating and without traditional extracorporal circulatory system Complete operation.Corrective surgery time and hospital stays will be greatly reduced in this, improve efficiency.
3rd, aortic cannulation is not needed during the utility model use, operative incision can be with microminiaturization.Operative incision is small, favorably Recover in patient, scar after the operation is small, meets patient's beauty requirement and mitigates patients ' psychological burden.When common room lacks operation in hospital Between will have and significantly reduce, save social cost, increase social benefit.
Brief description of the drawings
Fig. 1 is right heart shunt pump vertical profile exploded view.
Fig. 2 is that right heart shunt pump uses schematic diagram;
Fig. 3 is results of animal figure.A is that the TNF-α of right heart shunt group and extracorporal circulatory system group activates comparison diagram;B is the right side The IL-1 activation comparison diagrams of heart turn of tidal stream group and extracorporal circulatory system group;C is that the IL-6 activation of right heart shunt group and extracorporal circulatory system group contrasts Figure.Compared with extracorporal circulatory system group, activation of the right heart shunt group to inflammatory factors such as TNF-α (A), IL-1 (B), IL-6 (C) is notable It is relatively low.**P<0.01.
Primary clustering symbol description
1st, vein end pipe joint;2nd, blood device is stored up;3rd, vein end unidirectional valve;4th, arterial end unidirectional valve;
5th, arterial end pipe joint;6th, piston;7th, superior vena cava;8th, inferior caval vein;9th, pulmonary artery.
Embodiment
With reference to specific embodiment, the utility model is expanded on further.It should be understood that these embodiments are merely to illustrate this Utility model rather than limitation the scope of the utility model.In addition, it is to be understood that reading the content of the utility model instruction Afterwards, those skilled in the art can make various changes or modifications to the utility model, and these equivalent form of values equally fall within this Shen Please appended claims limited range.
Embodiment
As shown in figure 1, the right heart shunt pump of the present embodiment, including the storage blood that can be connected respectively with vena cave and pulmonary artery Device 2, and for driving blood to flow into the turn of tidal stream for storing up in blood device 2 and flowing into pulmonary artery out of storage blood device 2 from vena cave Device.
Described storage blood device 2 includes shell, and described shell is tubulose, including main line and bye-pass, described Main line and bye-pass are all cylindrical structure, and the two is combined into Y-shaped structure.Described storage blood device 2 have into blood mouth and Blood outlet, described enter blood mouth and blood outlet connect in the middle part of the both ends of main line, described bye-pass and main line respectively Connect.It is described to enter blood mouth and blood outlet is respectively equipped with the vein end pipe joint 1 that be connected with vena cave and can moved with lung The arterial end pipe joint 5 of arteries and veins connection.
Described blood shunting device includes vein end unidirectional valve 3 and arterial end unidirectional valve 4, and described vein end is unidirectionally lived Valve 3 and arterial end unidirectional valve 4 are respectively arranged on the entering in blood mouth and blood outlet of described storage blood device 2, vein end unidirectional valve 3 Opening direction be towards inside storage blood device 2, when vein end unidirectional valve 3 is opened, described vena cave is with storing up blood device 2 Between connect, when vein end unidirectional valve 3 is closed, described vena cave and storage blood device 2 between do not connect, described artery The opening direction for holding unidirectional valve 4 is towards housing exterior, when arterial end unidirectional valve 4 is opened, described pulmonary artery and storage Connect between blood device 2, when arterial end unidirectional valve 4 is closed, do not connected between described pulmonary artery and storage blood device 2;Institute The blood shunting device stated also includes being used for the driving dress for driving vein end unidirectional valve 3 and arterial end unidirectional valve 4 to open and close Put.
Described is used to drive the drive device bag that vein end unidirectional valve 3 and arterial end unidirectional valve 4 open and close Piston 6 is included, described piston 6 is located in described bye-pass, and described piston 6 is driven using power set, described power Device is motor.When piston 6 inwardly moves, vein end unidirectional valve 3 is closed, and arterial end unidirectional valve 4 is opened, when piston 6 When moving out, vein end unidirectional valve 3 is opened, and arterial end unidirectional valve 4 is closed.
Described shell and piston 6 is adopted made of plastic.Described enclosure capacity is 100ml.Described vein end Unidirectional valve 3 and arterial end unidirectional valve 4 are artificial valve.
Right heart shunt pump of the present utility model can be placed in thoracic cavity or external.In use, as shown in Fig. 2 storage blood dress Preliminary filling liquid in 2 is put, described vein end pipe joint 1 is connected by heart cathetrization with superior vena cava 7 and inferior caval vein 8, Described arterial end pipe joint 5 is connected by heart cathetrization with pulmonary artery 9, forms closed pipe-line system, and piston 6 is to outward transport When dynamic, negative pressure is produced in shell, blood flows into storage blood device 2 from vena cave through vein end unidirectional valve 3.Piston 6 inwardly moves When, shell is interior to produce malleation, and vein end unidirectional valve 3 is closed, and arterial end unidirectional valve 4 opens, and blood flows out of storage blood device 2 Enter pulmonary artery.During right heart shunt pump work, right heart blood can be fully drawn, and is pumped directly into pulmonary artery, is provided for the operation of the right heart Clearly operating field relatively.Right heart shunt pump can be placed in thoracic cavity, aid in the right heart to work so that and right cardiac load substantially reduces, It is particularly advantageous to the post-operative recovery of right heart failure and patients with pulmonary hypertension.
It is as follows that zoopery is carried out using right heart shunt pump of the present utility model:
Experiment material:Experimental Miniature Pig 12,23.4 ± 2.3Kg of body weight.It is randomly divided into two groups (every group 6).Experiment Group:Right heart shunt group;Control group:Routine in vitro circulates turn of tidal stream group.
Experimental method:After anaesthetizing successfully, experiment pig is lain on the back, median incision opens chest.Cut pericardium and fully expose heart.It is real Test and group take upper and lower cavity and aortic cannulation with upper and lower cavity and pulmonary arterial catheter, control group.Two groups of intubation turns of tidal stream hinder after starting Disconnected upper and lower cavity, heart beating turn of tidal stream 120 minutes, after the filtering of the blood back such as coronary sinus vein directly in defeated time experiment pig body.Respectively Before turn of tidal stream starts (T1), turn of tidal stream starts rear 120min (T2), and 120min (T3) gathers venous blood after shutdown, using R&D companies ELISA kit according to operating instruction detect TNF-α, the inflammation index such as IL-1, IL-6.
Experimental result:Right heart shunt group and extracorporal circulatory system group animal turn of tidal stream 2 hours under the conditions of general anesthesia.Blood flow in art Mechanics situation is shown in Table 1.Compared with traditional extracorporal circulatory system, during right heart shunt or after process, blood pressure, heart rate and central venous pressure Etc. index without significant difference.Therefore, right heart shunt can be carried out safely and effectively in animal body.Further detect TNF-α, IL-1, The inflammation indexes such as IL-6, traditional extracorporal circulatory system significantly activate body inflammatory reaction, show as inflammatory factor and significantly raise.With compareing Group is compared, and activation of the right heart shunt to inflammatory factor be not notable (Fig. 3).In summary, right heart shunt is safely and effectively to follow Ring turn of tidal stream mode, there is the advantages that wound is small, small to body interference.
The blood stream rheology of experiment pig before and after the turn of tidal stream of table 1.

Claims (10)

1. a kind of right heart shunt pump, it is characterised in that including the storage blood device that can be connected respectively with vena cave and pulmonary artery (2), and for driving blood to flow into storage blood device from vena cave(2)It is interior and from storage blood device(2)It is interior to flow into turning for pulmonary artery Flow device.
2. right heart shunt pump as claimed in claim 1, it is characterised in that described storage blood device(2)Have into blood mouth and go out Blood mouth, it is described to enter blood mouth and blood outlet is respectively equipped with the vein end pipe joint that be connected with vena cave(1)With can be with The arterial end pipe joint of pulmonary artery connection(5).
3. right heart shunt pump as claimed in claim 2, it is characterised in that described vein end pipe joint(1)And arterial end Pipe joint(5)It is connected respectively by pipeline with vena cave and pulmonary artery, described pipeline is heart cathetrization, artificial blood vessel or two The combination of person.
4. right heart shunt pump as claimed in claim 1, it is characterised in that described blood shunting device includes vein end unidirectional valve (3)With arterial end unidirectional valve(4), described vein end unidirectional valve(3)With arterial end unidirectional valve(4)It is respectively arranged on described Storage blood device(2)Enter in blood mouth and blood outlet, vein end unidirectional valve(3)Opening direction be towards storage blood device(2) Inside, when vein end unidirectional valve(3)During unlatching, described vena cave and storage blood device(2)Between connect, when vein end is unidirectional Flap valve(3)During closing, described vena cave and storage blood device(2)Between do not connect, described arterial end unidirectional valve(4)Open It is towards housing exterior, when arterial end unidirectional valve to open direction(4)During unlatching, described pulmonary artery and storage blood device(2)Between Connection, when arterial end unidirectional valve(4)During closing, described pulmonary artery and storage blood device(2)Between do not connect;Described turn of tidal stream Device also includes being used to drive vein end unidirectional valve(3)With arterial end unidirectional valve(4)The drive device of opening and closing.
5. right heart shunt pump as claimed in claim 4, it is characterised in that described vein end unidirectional valve(3)For artificial valve Film, biovalve or one way stop peturn valve.
6. right heart shunt pump as claimed in claim 4, it is characterised in that described arterial end unidirectional valve(4)For artificial valve Film, biovalve or one way stop peturn valve.
7. right heart shunt pump as claimed in claim 4, it is characterised in that described storage blood device(2)It is described including shell Shell is tubulose, including main line and bye-pass, the described both ends for entering blood mouth and blood outlet and being located at main line respectively, described Bye-pass and the middle part of main line connect, it is described to be used to drive vein end unidirectional valve(3)With arterial end unidirectional valve(4) The drive device of opening and closing includes piston(6), described piston(6)In described bye-pass, work as piston(6)Inwardly During motion, vein end unidirectional valve(3)Close, arterial end unidirectional valve(4)Open, work as piston(6)When moving out, vein end Unidirectional valve(3)Open, arterial end unidirectional valve(4)Close.
8. right heart shunt pump as claimed in claim 7, it is characterised in that described main line and bye-pass is all cylinder Structure, the two combines T-shaped or Y-shaped structure.
9. right heart shunt pump as claimed in claim 7, it is characterised in that described piston(6)Driven using power set.
10. right heart shunt pump as claimed in claim 9, it is characterised in that described power set are motor.
CN201621051107.XU 2016-09-12 2016-09-12 A kind of right heart shunt pump Expired - Fee Related CN206792725U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111481763A (en) * 2020-04-24 2020-08-04 南京鼓楼医院 Pulse type artificial lung extracorporeal circulation manager
CN116549762A (en) * 2023-07-10 2023-08-08 北京悦唯医疗科技有限责任公司 Left ventricle auxiliary device

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111481763A (en) * 2020-04-24 2020-08-04 南京鼓楼医院 Pulse type artificial lung extracorporeal circulation manager
CN116549762A (en) * 2023-07-10 2023-08-08 北京悦唯医疗科技有限责任公司 Left ventricle auxiliary device
CN116549762B (en) * 2023-07-10 2023-10-31 北京悦唯医疗科技有限责任公司 Left ventricle auxiliary device

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Granted publication date: 20171226

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