CN104984315B - A kind of foot-bathing Chinese medicine preparation and preparation method thereof - Google Patents
A kind of foot-bathing Chinese medicine preparation and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to health care product technical fields, and in particular to a kind of foot-bathing Chinese medicine preparation and preparation method thereof.A kind of foot-bathing Chinese medicine preparation, it is prepared from the following raw materials by weight, 3-10 parts of tea leaf powder, 5-20 parts of folium artemisiae argyi, 1-5 parts of Rhizoma Atractylodis Macrocephalae, 8-20 parts of the root of fangji, 5-10 parts of rhizoma zingiberis, 5-15 parts of Cortex Eucommiae, 1-10 parts of radix achyranthis bidentatae, 1-5 parts of rhizoma acori graminei, 5-10 parts of rhizoma alismatis, 1-10 parts of Radix Angelicae Sinensis, 1-5 parts of rhizoma cyperi, 1-10 parts of Rhizoma Chuanxiong, 1-8 parts of Radix Astragali, 1-2 parts of safflower, 1-5 parts of Morinda officinalis, 2-5 parts of Fructus Corni, 1-5 parts of cortex cinnamomi, 2-6 parts of pueraria lobata, 1-2 parts of Schisandra chinensis, 2-5 parts of kuh-seng, 3-8 parts of aloe, 0-2 parts of essential oil, 0-5 parts of menthol, 0-5 parts of borneol, 20-75 parts of auxiliary material.A kind of preparation method of foot-bathing Chinese medicine preparation, including to prepare extract powder, volatile oil clathrate compound and essential oil clathrate mixed for feeding, extraction.The present invention proposes a kind of foot-bathing Chinese medicine preparation and preparation method thereof, solves the problem of that lavipeditum product is extensive, function and effect are unobvious, experience sense is not strong and is mostly chemicals.
Description
Technical field
The present invention relates to health care product technical fields, and in particular to a kind of foot-bathing Chinese medicine preparation and preparation method thereof.
Background technique
Lavipeditum has long history as one of external treatment of traditional Chinese medicine.In recent years, lavipeditum is supported as a kind of simple and easy
Raw health care mode increasingly prosperity is got up.Good " hundred steps are walked after meal, sleep previous bathtub cubicle " that old saying is said, steeps foot before sleeping, victory eats tonic, foot
Also referred to as " the second heart " of human body, it is one piece of mystery " organ " for containing unlimited precious deposits, the heart of the foot from human body on human body
It is dirty farthest, and bear most heavy, if steeping foot daily, be equal to add a pump in the lower part of body, can help one arm of heart it
Power makes blood backflow unimpeded.Huangdi's Internal Classics think that " yang-energy arises from the table of five toes of foot, and negative gas arises from the reason of five toes of foot."
The three yang channels of foots (stomach, gallbladder, bladder) terminate in leg foot, and it is that yin and yang mixture is understood here that Three Yin Channels of Foot (liver,spleen,kidney), which arises from leg foot,
Place is dispersed with a acupuncture point more than 60 on shank, and foot has nearly 70 echo areas, and biped and whole body yin-yang, qi and blood, channels and collaterals have closely
Connection.By lavipeditum, acupoint of foot can be stimulated, body-building, being especially added during lavipeditum has special efficacy
Herb medicine has the function that be healthy and strong except disease while health care.
Current lavipeditum product is extensive, function and effect are unobvious, experience sense is not strong, and is mostly chemicals.
Effervescent tablet is a kind of excellent solid novel form developed in recent years, is using suitable bronsted lowry acids and bases bronsted lowry as disintegrating agent
It is made and meets water generation CO2 gas, a kind of preparation of effervesce shape is presented, is obtained in food, health care product, medicine field more and more extensive
Application, it and ordinary solid preparation meet water (hot, cold, ice water) rapidly the difference is that contain gas-producing disintegrant
Great amount of carbon dioxide is generated, dissolves contained ingredient quickly, is conducive to improve bioavilability.Chinese medicine effervescent formulation is former auxiliary
Expect that the various aspects such as selection, production technology, working condition are more stringent and difficult compared with conventional formulation, a kind of its new agent
Type has many advantages, such as that drug release rate is fast, dosage is small, divided dose is accurate, takes, is easy to carry, can preferably play curative effect effect.
Summary of the invention
In order to solve the above technical problems, the present invention proposes a kind of foot-bathing Chinese medicine preparation and preparation method thereof, solves lavipeditum and produce
Product are extensive, function and effect are unobvious, experience sense is not strong, and the problem of be mostly chemicals；Product of the invention has well
Health-care effect, and quickly experience, efficient, easy to carry, product is exquisite, green, healthy, safe.Its technical solution are as follows:
A kind of foot-bathing Chinese medicine preparation, is prepared from the following raw materials by weight, 3-10 parts of tea leaf powder, 5-20 parts of folium artemisiae argyi, Rhizoma Atractylodis Macrocephalae
1-5 parts, 8-20 parts of the root of fangji, 5-10 parts of rhizoma zingiberis, 5-15 parts of Cortex Eucommiae, 1-10 parts of radix achyranthis bidentatae, 1-5 parts of rhizoma acori graminei, 5-10 parts of rhizoma alismatis, Radix Angelicae Sinensis
1-10 parts, 1-5 parts of rhizoma cyperi, 1-10 parts of Rhizoma Chuanxiong, 1-8 parts of Radix Astragali, 1-2 parts of safflower, 1-5 parts of Morinda officinalis, 2-5 parts of Fructus Corni, cortex cinnamomi
1-5 parts, 2-6 parts of pueraria lobata, 1-2 parts of Schisandra chinensis, 2-5 parts of kuh-seng, 3-8 parts of aloe, 0-2 parts of essential oil, 0-5 parts of menthol, borneol 0-5
Part, 20-75 parts of auxiliary material.
Further, essential oil include tea tree ethereal oil, it is Lavender, Rosa Damascana, one or several kinds of in jasmine essential oil.
A kind of preparation method of foot-bathing Chinese medicine preparation, including following step of preparation process:
(1) feeding
3-10 parts of tea leaf powder, 5-20 parts of folium artemisiae argyi, 1-5 parts of Rhizoma Atractylodis Macrocephalae, 8-20 parts of the root of fangji, 5-10 parts of rhizoma zingiberis, Du are taken by weight
5-15 parts secondary, 1-10 parts of radix achyranthis bidentatae, 1-5 parts of rhizoma acori graminei, 5-10 parts of rhizoma alismatis, 1-10 parts of Radix Angelicae Sinensis, 1-5 parts of rhizoma cyperi, 1-10 parts of Rhizoma Chuanxiong, Huang
1-8 parts of stilbene, 1-2 parts of safflower, 1-5 parts of Morinda officinalis, 2-5 parts of Fructus Corni, 1-5 parts of cortex cinnamomi, 2-6 parts of pueraria lobata, 1-2 parts of Schisandra chinensis, hardship
Join 2-5 parts, 3-8 parts of aloe, 0-2 parts of essential oil, 0-5 parts of menthol, 0-5 parts of borneol, 20-75 parts of auxiliary material；
The above Chinese medicine is cleaned respectively, dries, crush, it is spare；
(2) take folium artemisiae argyi, Rhizoma Chuanxiong, Radix Angelicae Sinensis, rhizoma acori graminei, Rhizoma Atractylodis Macrocephalae, Fructus Corni Six-element medicine using supercritical CO2Extraction extraction is waved
Hair oil, supercritical CO2Extracting pressure is controlled in 15-40MPa, separator pressure 15-25MPa, CO2Flow velocity is 10-50L/h, extraction
Temperature is 25 DEG C -50 DEG C, and extraction time is extracts under the conditions of 2-3h state modulator, and collection volatile oil is spare；
(3) dregs of a decoction in above-mentioned steps (2) are merged with remaining Chinese medicine and is added water to cook 2 times, 8 times of amounts are added for the first time
Water, second of addition, 6 times of amount water, each 1.5h merge secondary decocting liquid, 300 mesh screens filtration, when filtrate decompression is concentrated into 80 DEG C
Surveyed relative density is 1.05, is then drying to obtain extract powder, spare；
(4) volatile oil extracted in step (2) is embedded using beta-cyclodextrin, obtains volatile oil clathrate compound, it is spare；
(5) essential oil is wrapped up, using chitosan or beta-cyclodextrin as wall material, obtains essential oil clathrate；
(6) extract powder, volatile oil clathrate compound and essential oil clathrate are uniformly mixed, add appropriate auxiliary material, lavipeditum is made
Product formulation.
Further, the lavipeditum product formulation is effervescent tablet.
Further, proportion is 1:3~3:1 between effervescent agent acid source and carbon dioxide source in above-mentioned effervescent tablet.
Further, effervescent agent carbon dioxide source can be wrapped up by the ethanol solution of polyethylene glycol in above-mentioned effervescent tablet.
The invention has the advantages that:
1, the footbath with traditional Chinese medicines product autonomic nerve adjustable for the puerpera of postpartum anxiety, postpartum depression of this patent preparation
And endocrine system, alleviate puerpera's anxiety, anxiety, it is made to possess pleasant mood and good sleep.
2, tea leaf powder, folium artemisiae argyi, Rhizoma Atractylodis Macrocephalae, the root of fangji, rhizoma zingiberis, Cortex Eucommiae, radix achyranthis bidentatae, rhizoma acori graminei, rhizoma alismatis, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Huang are selected
Stilbene, safflower, Morinda officinalis, Fructus Corni, cortex cinnamomi, pueraria lobata, Schisandra chinensis, kuh-seng, aloe combination are prepared, and have expelling wind and clearing away cold, remove
Wet detumescence, relaxing tendons and activating collaterals promote sufficient flesh to moisten whitening, and activating microcirculation and removing stasis medicinal improves menalgia, temperature male wind-supplying kidney, and kidney-nourishing mends body, promote
Blood circulation, calm effect of calming the nerves.Be equipped with tea leaf powder, folium artemisiae argyi, Rhizoma Atractylodis Macrocephalae, the root of fangji, rhizoma alismatis, rhizoma zingiberis, Cortex Eucommiae, radix achyranthis bidentatae, rhizoma acori graminei,
Pueraria lobata, aloe etc. have dispelling wind and eliminating dampness, and inducing diuresis for removing edema, nourishing the liver and kidney, strengthening the bones and muscles, temperature is through beauty treatment, soft skin and other effects drug
Combination is used as monarch drug in a prescription, is aided with the drug of Qi and blood deficiency with the invigorating QI and bloods such as Radix Angelicae Sinensis, Rhizoma Chuanxiong, rhizoma cyperi, safflower, Radix Astragali, the prosperous then gas of blood
Foot, activating microcirculation and removing stasis medicinal improve menalgia, cooperate dispelling wind and eliminating dampness, and detumescence drug plays a role as ministerial drug；Assistant is with Morinda officinalis, mountain Zhu
The kidney tonifying of the middle benefit gas such as cornel, cortex cinnamomi, kidney-nourishing kidney tonifying improve immunity；It is to make medicine with Schisandra chinensis, kuh-seng inducting the medicines into affected channel.Monarch drug in a prescription, ministerial drug, assistant
Medicine and medicine is made to cooperate, so that the active constituent in each medicinal material generates synergistic effect, mutually promotes its effect.
3, essential oil and volatile oil used when present invention preparation are to be wrapped up essential oil by microcapsules technology pack,
Using chitosan or beta-cyclodextrin as wall material, the stability of essential oil is improved.
4, in order to avoid alkali source is directly contacted with acid source, the pack of polyethylene glycol micro-capsule can be selected and wrap up sodium bicarbonate
Come, moisture-proof effect can also be played, extend the effective time of effervescent tablet.
5, foot-bathing Chinese medicine preparation of the present invention is with quick, cure rate is high, stresses conditioning, treating both manifestation and root cause of disease, uneasy to recur etc.
Technical advantage；Finished product preparation convenient to use is made in the case where guaranteeing drug effect, raw material is simple, and preparation process is easy, medicine
Imitate the advantages such as stabilization, the small, application easy to spread of medication individual difference.
6, lavipeditum preparation of the invention adds 20 plurality of Chinese extracts, and prescription is prepared by the scientific and reasonable compatibility, and uses
The conventional method of Chinese materia medica preparation is prepared into the lavipeditum product of different dosage forms, has inducing diuresis for removing edema, latus rectum clearing damp, relaxing tendons and activating collaterals, benefit
Kidney mends body, and temperature is through beauty treatment, promoting blood circulation for regulating menstruation, menstruction regulating and pain relieving, soft skin, the health-care effect of bacterio static itching-relieving, antitoxic heart-soothing and sedative.
Following clinical trial further illustrates the advantages of lavipeditum preparation and institute attainable technical effect.
(1) general information:
Lavipeditum preparation of the present invention is that treatment has arthralgia, varix of lower limb, menalgia, the patients such as rheumatismal edema
Clinical observation.
Lavipeditum preparation of the present invention acquires 120 clinical cases altogether, and male 45, the age 35-70 years old；Women 45, the age
At 35-70 years old；Blank control group 30, the age 35-70 years old.Using using lavipeditum formulation products of the present invention and 38 DEG C -45 DEG C
Clear water foot bath is done control mode and is compared, wherein 90 people for the treatment of group, 30 people of control group.
(2) application method: taking this lavipeditum formulation products, is added in 38-45 DEG C of clear water, after dissolving composition, into
Row lavipeditum, medical fluid flooded ankle part, slow rubbing 15-30min when lavipeditum, and daily foot bath 1-3 times is used continuously 30 days, tested
Person stops using other foot bath health care products during test.
Control group uses 38-45 DEG C of clear water foot bath daily, and each 15-30min is 1-3 times daily, and continuous 30 days.
(3) curative effect judging standard
Cure: medication 30 days, clinical symptoms all disappeared；Effective: medication 30 days, symptom was substantially reduced, most of sign
It disappears；It is invalid: medication 30 days, symptom and sign cannot to be made to disappear.
(4) test result
Experimental result is as shown in table 1
Table 1
The result shows that: this lavipeditum preparation is in treatment arthralgia, varix of lower limb, menalgia, rheumatismal edema etc.
The treatment rate of symptom reaches 72%, and total effective percentage reaches 94%.
Specific embodiment
Embodiment one
Prepare foot-bathing Chinese medicine preparation of the invention in accordance with the following steps:
(1) feeding
G by weight take tea leaf powder 3g, folium artemisiae argyi 5g, Rhizoma Atractylodis Macrocephalae 1g, root of fangji 8g, rhizoma zingiberis 5g, Cortex Eucommiae 5g, radix achyranthis bidentatae 1g, rhizoma acori graminei 1g,
Rhizoma alismatis 5g, Radix Angelicae Sinensis 1g, rhizoma cyperi 1g, Rhizoma Chuanxiong 1g, Radix Astragali 1g, safflower 1g, Morinda officinalis 1g, Fructus Corni 2g, cortex cinnamomi 1g, pueraria lobata 2g, five
Taste 1g, kuh-seng 2g, aloe 3g, auxiliary material 20g；
Essential oil includes tea tree ethereal oil, Lavender, Rosa Damascana, one or several kinds of in jasmine essential oil
The above Chinese medicine is cleaned respectively, dries, crush, it is spare；
(2) take folium artemisiae argyi, Rhizoma Chuanxiong, Radix Angelicae Sinensis, rhizoma acori graminei, Rhizoma Atractylodis Macrocephalae, Fructus Corni Six-element medicine using supercritical CO2Extraction extraction is waved
Hair oil, supercritical CO2Extracting pressure is controlled in 15MPa, separator pressure 15MPa, CO2Flow velocity is 10L/h, extraction temperature 25
DEG C, extraction time is extracts under the conditions of the state modulators such as 2h, collection volatile oil is spare；
(3) dregs of a decoction in above-mentioned steps 2 are merged with remaining Chinese medicine and are added water to cook 2 times, 8 times of amount water are added for the first time,
Second is added 6 times of amount water, and each 1.5h merges secondary decocting liquid, and 300 mesh screens filter, filtrate decompression be concentrated into 80 DEG C when institute
Surveying relative density is 1.05, is then drying to obtain extract powder, spare；
(4) volatile oil extracted in step 2 is embedded using beta-cyclodextrin, obtains volatile oil clathrate compound, it is spare；
(5) essential oil is wrapped up, using chitosan or beta-cyclodextrin as wall material, obtains essential oil clathrate；
(6) extract powder, volatile oil clathrate compound and essential oil clathrate are uniformly mixed, add appropriate auxiliary material, lavipeditum is made
Product formulation.It is prepared into effervescent tablet using the method for preparing effervescent tablet, effervescent agent acid source and carbon dioxide source in above-mentioned effervescent tablet
Between proportion be 1:3, effervescent agent carbon dioxide source can be wrapped up by the ethanol solution of polyethylene glycol in effervescent tablet.
Embodiment two
Prepare foot-bathing Chinese medicine preparation of the invention in accordance with the following steps:
(1) feeding
G by weight takes tea leaf powder 7g, folium artemisiae argyi 10g, Rhizoma Atractylodis Macrocephalae 3g root of fangji 10g, rhizoma zingiberis 7g, Cortex Eucommiae 10g, radix achyranthis bidentatae 9g, rhizoma acori graminei
4g, rhizoma alismatis 8g, Radix Angelicae Sinensis 5g, rhizoma cyperi 2g, Rhizoma Chuanxiong 5g, Radix Astragali 6g, safflower 2g, Morinda officinalis 3g, Fructus Corni 3g, cortex cinnamomi 3g, pueraria lobata 4g,
Schisandra chinensis 2g, kuh-seng 3g, aloe 5g, essential oil 1g, menthol 3g, borneol 3g, auxiliary material 50g；
Essential oil includes tea tree ethereal oil, Lavender, Rosa Damascana, one or several kinds of in jasmine essential oil
The above Chinese medicine is cleaned respectively, dries, crush, it is spare；
(2) take folium artemisiae argyi, Rhizoma Chuanxiong, Radix Angelicae Sinensis, rhizoma acori graminei, Rhizoma Atractylodis Macrocephalae, Fructus Corni Six-element medicine using supercritical CO2Extraction extraction is waved
Hair oil, supercritical CO2Extracting pressure is controlled in 20MPa, separator pressure 18MPa, CO2Flow velocity is 30L/h, extraction temperature 40
DEG C, extraction time is extracts under the conditions of the state modulators such as 2.5h, collection volatile oil is spare；
(3) dregs of a decoction in above-mentioned steps 2 are merged with remaining Chinese medicine and are added water to cook 2 times, 8 times of amount water are added for the first time,
Second is added 6 times of amount water, and each 1.5h merges secondary decocting liquid, and 300 mesh screens filter, filtrate decompression be concentrated into 80 DEG C when institute
Surveying relative density is 1.05, is then drying to obtain extract powder, spare；
(4) volatile oil extracted in step 2 is embedded using beta-cyclodextrin, obtains volatile oil clathrate compound, it is spare；
(5) essential oil is wrapped up, using chitosan or beta-cyclodextrin as wall material, obtains essential oil clathrate；
(6) extract powder, volatile oil clathrate compound and essential oil clathrate are uniformly mixed, add appropriate auxiliary material, lavipeditum is made
Product formulation.It is prepared into effervescent tablet using the method for preparing effervescent tablet, effervescent agent acid source and carbon dioxide source in above-mentioned effervescent tablet
Between proportion be 2:1, effervescent agent carbon dioxide source can be wrapped up by the ethanol solution of polyethylene glycol in effervescent tablet.
Embodiment three
Prepare foot-bathing Chinese medicine preparation of the invention in accordance with the following steps:
(1) feeding
G by weight takes tea leaf powder 10g, folium artemisiae argyi 20g, Rhizoma Atractylodis Macrocephalae 5g root of fangji 20g, rhizoma zingiberis 10g, Cortex Eucommiae 15g, radix achyranthis bidentatae 10g, stone Chang
Pu 5g, rhizoma alismatis 10g, Radix Angelicae Sinensis 10g, rhizoma cyperi 5g, Rhizoma Chuanxiong 10g, Radix Astragali 8g, safflower 2g, Morinda officinalis 5g, Fructus Corni 5g, cortex cinnamomi 5g, Pueraria lobota
Root 6g, Schisandra chinensis 2g, kuh-seng 5g, aloe 8g, essential oil 2g, menthol 5g, borneol 5g, auxiliary material 75g；
Essential oil includes tea tree ethereal oil, Lavender, Rosa Damascana, one or several kinds of in jasmine essential oil
The above Chinese medicine is cleaned respectively, dries, crush, it is spare；
(2) take folium artemisiae argyi, Rhizoma Chuanxiong, Radix Angelicae Sinensis, rhizoma acori graminei, Rhizoma Atractylodis Macrocephalae, Fructus Corni Six-element medicine using supercritical CO2Extraction extraction is waved
Hair oil, supercritical CO2Extracting pressure is controlled in 40MPa, separator pressure 25MPa, CO2Flow velocity is 50L/h, extraction temperature 50
DEG C, extraction time is extracts under the conditions of the state modulators such as 2-3h, collection volatile oil is spare；
(3) dregs of a decoction in above-mentioned steps 2 are merged with remaining Chinese medicine and are added water to cook 2 times, 8 times of amount water are added for the first time,
Second is added 6 times of amount water, and each 1.5h merges secondary decocting liquid, and 300 mesh screens filter, filtrate decompression be concentrated into 80 DEG C when institute
Surveying relative density is 1.05, is then drying to obtain extract powder, spare；
(4) volatile oil extracted in step 2 is embedded using beta-cyclodextrin, obtains volatile oil clathrate compound, it is spare；
(5) essential oil is wrapped up, using chitosan or beta-cyclodextrin as wall material, obtains essential oil clathrate；
(6) extract powder, volatile oil clathrate compound and essential oil clathrate are uniformly mixed, add appropriate auxiliary material, lavipeditum is made
Product formulation.It is prepared into effervescent tablet using the method for preparing effervescent tablet, effervescent agent acid source and carbon dioxide source in above-mentioned effervescent tablet
Between proportion be 3:1, effervescent agent carbon dioxide source can be wrapped up by the ethanol solution of polyethylene glycol in effervescent tablet.
Claims (6)
1. a kind of foot-bathing Chinese medicine preparation, it is characterised in that: be prepared from the following raw materials by weight, 3-10 parts of tea leaf powder, folium artemisiae argyi 5-
20 parts, 1-5 parts of Rhizoma Atractylodis Macrocephalae, 8-20 parts of the root of fangji, 5-10 parts of rhizoma zingiberis, 5-15 parts of Cortex Eucommiae, 1-10 parts of radix achyranthis bidentatae, 1-5 parts of rhizoma acori graminei, rhizoma alismatis 5-
10 parts, 1-10 parts of Radix Angelicae Sinensis, 1-5 parts of rhizoma cyperi, 1-10 parts of Rhizoma Chuanxiong, 1-8 parts of Radix Astragali, 1-2 parts of safflower, 1-5 parts of Morinda officinalis, Fructus Corni 2-
5 parts, 1-5 parts of cortex cinnamomi, 2-6 parts of pueraria lobata, 1-2 parts of Schisandra chinensis, 2-5 parts of kuh-seng, 3-8 parts of aloe, 0-2 parts of essential oil, menthol 0-5
Part, 0-5 parts of borneol, 20-75 parts of auxiliary material.
2. a kind of foot-bathing Chinese medicine preparation according to claim 1, which is characterized in that essential oil includes tea tree ethereal oil, lavender essence
It is oil, Rosa Damascana, one or several kinds of in jasmine essential oil.
3. a kind of preparation method of foot-bathing Chinese medicine preparation according to claim 1, it is characterised in that including following preparation process
Step:
(1) feeding
3-10 parts of tea leaf powder, 5-20 parts of folium artemisiae argyi, 1-5 parts of Rhizoma Atractylodis Macrocephalae, 8-20 parts of the root of fangji, 5-10 parts of rhizoma zingiberis, Cortex Eucommiae 5- are taken by weight
15 parts, 1-10 parts of radix achyranthis bidentatae, 1-5 parts of rhizoma acori graminei, 5-10 parts of rhizoma alismatis, 1-10 parts of Radix Angelicae Sinensis, 1-5 parts of rhizoma cyperi, 1-10 parts of Rhizoma Chuanxiong, Radix Astragali 1-
8 parts, 1-2 parts of safflower, 1-5 parts of Morinda officinalis, 2-5 parts of Fructus Corni, 1-5 parts of cortex cinnamomi, 2-6 parts of pueraria lobata, 1-2 parts of Schisandra chinensis, kuh-seng 2-5
Part, 3-8 parts of aloe, 0-2 parts of essential oil, 0-5 parts of menthol, 0-5 parts of borneol, 20-75 parts of auxiliary material；
The above Chinese medicine is cleaned respectively, dries, crush, it is spare；
(2) take folium artemisiae argyi, Rhizoma Chuanxiong, Radix Angelicae Sinensis, rhizoma acori graminei, Rhizoma Atractylodis Macrocephalae, Fructus Corni Six-element medicine using supercritical CO2Extraction extracts volatile oil,
Supercritical CO2Extracting pressure is controlled in 15-40MPa, separator pressure 15-25MPa, CO2Flow velocity is 10-50L/h, extraction temperature
It is 25 DEG C -50 DEG C, extraction time is extracts under the conditions of 2-3h state modulator, collection volatile oil is spare；
(3) dregs of a decoction in above-mentioned steps (2) are merged with remaining Chinese medicine and is added water to cook 2 times, 8 times of amount water are added for the first time, the
6 times of amount water of secondary addition, each 1.5h merge secondary decocting liquid, the filtration of 300 mesh screens, and filtrate decompression is surveyed when being concentrated into 80 DEG C
Relative density is 1.05, is then drying to obtain extract powder, spare；
(4) volatile oil extracted in step (2) is embedded using beta-cyclodextrin, obtains volatile oil clathrate compound, it is spare；
(5) essential oil is wrapped up, using chitosan or beta-cyclodextrin as wall material, obtains essential oil clathrate；
(6) extract powder, volatile oil clathrate compound and essential oil clathrate are uniformly mixed, add appropriate auxiliary material, lavipeditum product is made
Preparation.
4. a kind of preparation method of foot-bathing Chinese medicine preparation according to claim 3, it is characterised in that: the lavipeditum product formulation
For effervescent tablet.
5. a kind of preparation method of foot-bathing Chinese medicine preparation according to claim 4, it is characterised in that effervesce in above-mentioned effervescent tablet
Proportion is 1:3~3:1 between agent acid source and carbon dioxide source.
6. a kind of preparation method of foot-bathing Chinese medicine preparation according to claim 5, it is characterised in that effervesce in above-mentioned effervescent tablet
Agent carbon dioxide source can be wrapped up by the ethanol solution of polyethylene glycol.
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| CN105687621A (en) * | 2016-01-29 | 2016-06-22 | 广州暨南生物医药研究开发基地有限公司 | Foot bath powder with functions of activating blood and resolving stasis and dispelling wind and removing dampness and preparation method thereof |
| CN105561002A (en) * | 2016-01-29 | 2016-05-11 | 广州暨南生物医药研究开发基地有限公司 | Folium artemisiae argyi health-care foot bath powder and preparation method thereof |
| CN105709020A (en) * | 2016-02-16 | 2016-06-29 | 广州暨南生物医药研究开发基地有限公司 | Foot bath powder with folium artemisiae argyi decoction dregs and preparation method thereof |
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| CN101061999A (en) * | 2006-04-25 | 2007-10-31 | 上海水产大学 | Health-care bath package including Chinese herbal medicine and the preparing method thereof |
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| CN103142953A (en) * | 2013-03-11 | 2013-06-12 | 郑汉 | Foot-bath health-protective Chinese medicament powder |
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