CN104984020A - Traditional Chinese medicinal preparation for treating hysteromyoma, and preparation method thereof - Google Patents
Traditional Chinese medicinal preparation for treating hysteromyoma, and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicinal preparation for treating hysteromyoma, and a preparation method thereof. The traditional Chinese medicinal preparation comprises Smilax scobinicaulis C.H. Wright, Centranthera cochinchinensis, Toxicodendron vernicifluum, Euonymus fortune, Wikstroemia canescens (Wall.) Meissn., cantharis sinica, Alocasia macrorrhiza, herba aristolochiae, Cyperus alternifolius, Polygonum cynanchoides Hemsl., anisetree bark, Bark of Chinese Redbud, Lindera fragrans, Garden Balsam Seed, Cissus modecoides, Root of Shrubberry Rhodiola, Root of Buerger Raspberry, Phlegmariurus austrosinicus (Ching) L. B. Zhang, Corydalis bungeana Turcz., Rhizoma Menispermi, Uncariasessilifructus Roxb., Tricyrtis pilosa Wall and Silene conoidea L.. The traditional Chinese medicinal preparation has the efficacies of invigorating blood circulation and removing blood stasis, moving qi and relieving pains, warming mid-energizer and dispersing cold, softening hardness and dispersing stasis, and eliminating swelling and relieving pains. The preparation method has the characteristics of simplicity, feasibility, safety, effectiveness, and substantial clinic effects.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of hysteromyoma and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Hysteromyoma is modal benign tumor in female genital diseases, be more common in the women of childbearing age, infertile, menoxenia, dysmenorrhea can be caused, it is the one of the main reasons causing hysterectomy, form primarily of smooth muscle cell proliferation, have a small amount of connective tissue therebetween, be more common in the women of 30 years old to 50 years old, less than 20 years old rare.Crowd's sickness rate, up to about 77%, has a strong impact on the physical and mental health of the women of child-bearing age.Current western medical treatment, mainly with estrin treatment, makes hysteromyoma atrophy, but is difficult to radical cure, and side effect is large, and patient is difficult to accept.Still easily recur after myomatectomy, and easily cause pelvic adhesion, or intestinal obstruction occurs, uterectomy directly can affect fertility, causes endocrine disturbance.Chinese medicine has unique advantage to the treatment of this type of disease and prevention, curative effect is reliable, toxic and side effects is little, clinical practice is safe feature that it has.Utilize Chinese medical discrimination normally to discuss and carry out treatment hysteromyoma disease, achieve good curative effect in clinical practice.
Hysteromyoma belongs to the category that Chinese medicine belongs to " lump in the abdomen ".Be also called " stony mass of uterus ".In " a Ling Shu Miraculous Pivot or Divine Axis edema section " day: " stony mass of uterus is born in born of the same parents, pathogenic cold invasion in the cervical orifice of the uterus, and cervical orifice of uterus is inaccessible, and gas must not lead to stagnant blood to be walked must not rush down, shrimp not only to stay, day to increase, shape as cherished son, irregular menstrual cycle ".Visible in the development course of disease of hysteromyoma, often with irregular menstrual period, menses increase, lumbago, and stomachache, is with the common disease of inferior multiple gynecological.Therefore " empty talk of Plain Questions bone " day: " conception vessel is disease ... woman's leukorrhagia abdominal mass is gathered ".Therefore the pathogenic process of primary disease and the dirty functional disorder of liver,spleen,kidney three, qi depression to blood stasis, or cold in blood then coagulates, and hear rate Tianjin blood etc. are relevant.Wherein the dirty functional disorder of liver,spleen,kidney three is core.The fire-transformation because of liver and gall stasis, damp invasion of lower energizer is then leukorrhagia; Heat
The visible metrorrhagia of the absurd row of forcing blood; Because of dysfunction of the spleen in transportation, wet from interior life then visible phlegm and qi stasis stay Yu Gongzhong; Deficiency of the kidney, essence and blood secretly consumes, and blood stasis stagnant blood stays in poly-palace, visible lower abdomen lump, stomachache, metrorrhagia, leukorrhagia.Though the cause of disease of primary disease has multiterminal, its pathogenesis mainly the stagnation of QI and cause in blood stasis tie.Clinical treatment is followed mostly, and " Plain Questions the most pure virginity will be discussed greatly " proposes.Hard masses should be resolved gradually, diseases with invaded pathogens should be treated by expelling, disease caused by accumulations of pathogen should be treated with therapy of dispersion, disease with retention of pathogen in the body should be treated by elimination therapy ".Can removing mass be made, can make to burst hard " method, adopt " blood circulation promoting and blood stasis dispelling, eliminating stagnation disappear abdominal mass " to be main.
Chinese medicine is in this type of disease for the treatment of, and through long-term clinical practice, the theory and practice experience of accumulating and enriching, has obvious advantage.
Summary of the invention
The object of the invention is to provide Chinese medicine preparation of a kind of effective in cure reliable, toxic and side effects is little, clinical practice is safe treatment hysteromyoma and preparation method thereof.
We's prolonged application treatment clinically hysteromyoma, obtains good curative effect.Rhizoma Smilacis Scobinicaulis is selected, promoting blood circulation and detoxication in side, anticancer; Herba Centrantherae Cochinchinensis, detumescence dissipating blood stasis; Resina Toxicodendri, removing blood stasis with potent drugs blood; Caulis Seu Folium Euonymi Fortunei, dissipating blood stasis stops blooding, relaxing muscles and tendons and activating QI and blood in the collateral; Flos Wikstroemiae Dolichanthae root, relaxing muscles and tendons and activating QI and blood in the collateral, mass dissipating and swelling eliminating; Lytta caragana Pallas, counteracting toxic substances, removing blood stasis; All medicine mutual reinforcements between are use, strengthen the effect of our blood circulation promoting and blood stasis dispelling, are equipped with Rhizoma alcasiae odorae, promoting the circulation of QI to relieve pain, mass dissipating and swelling eliminating; Herba Aristolochiae, promoting flow of QI and blood, inducing diuresis to remove edema; Umbrella plant, promoting flow of QI and blood; Hair and blood rattan, circulation of qi promoting is eased pain; Cortex Illicii, promoting the circulation of QI to relieve pain; Cortex cercis chinensis, invigorates blood circulation, removing toxic substances; We are made to have effect of promoting the circulation of QI to relieve pain concurrently.Fang Zhongzai joins Cortex Linderae Fragrantis, warming middle-JIAO to promote flow of QI, expelling wind and cold; Semen Impatientis, removing blood stasis softening the hard mass, removing food stagnancy; Cissus repens, dissipating phlegm and resolving masses, subduing swelling and detoxicating; Radix Rhodiolae Dumulosae, hard masses softening and resolving, blood stasis dispelling relaxing muscles and tendons; Full side is made to have the merit of warming spleen and stomach for dispelling cold, hard masses softening and resolving.Finally be equipped with Radix rubi buergeri again, promoting blood circulation and stopping pain; Muntjac grass, reducing swelling and alleviating pain; Herba Corydalis Bungeanae, promoting blood circulation and detumescence; Rhizoma Menispermi, reducing swelling and alleviating pain; Uncaria sessilifructus Roxb, promoting blood circulation to restore menstrual flow; Herba Tricyrtis Pilosae, promoting blood circulation and detumescence; Due to the strongly fragrant multipotency heat-transformation of a specified duration of primary disease blood stasis, therefore compatibility Herba Silenes conoideae, clearing away heat and cooling blood, blood-arresting catamenia-regulating.All medicines coordinate, strengthening vital QI to eliminate pathogenic factors, giving consideration to both the incidental and fundamental, and make full side play effect of blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, warming spleen and stomach for dispelling cold, hard masses softening and resolving, reducing swelling and alleviating pain altogether, the blood vessels making the stasis of blood stagnant are again unimpeded, reach the object of blood clot dispersing and tumor eliminating.
The Chinese medicine preparation of the hysteromyoma for the treatment of of the present invention, it is made up of the raw material of following weight proportion: Rhizoma Smilacis Scobinicaulis 40 ~ 60 parts, Herba Centrantherae Cochinchinensis 40 ~ 60 parts, Resina Toxicodendri 20 ~ 40 parts, Caulis Seu Folium Euonymi Fortunei 20 ~ 40 parts, Flos Wikstroemiae Dolichanthae root 30 ~ 50 parts, Lytta caragana Pallas 10 ~ 30 parts, Rhizoma alcasiae odorae 20 ~ 40 parts, Herba Aristolochiae 20 ~ 30 parts, umbrella plant 20 ~ 30 parts, 20 ~ 40 parts, hair and blood rattan, Cortex Illicii 20 ~ 40 parts, Cortex cercis chinensis 20 ~ 30 parts, Cortex Linderae Fragrantis 10 ~ 30 parts, Semen Impatientis 30 ~ 50 parts, Cissus repens 20 ~ 30 parts, Radix Rhodiolae Dumulosae 20 ~ 40 parts, Radix rubi buergeri 10 ~ 30 parts, muntjac grass 20 ~ 40 parts, Herba Corydalis Bungeanae 10 ~ 30 parts, Rhizoma Menispermi 30 ~ 50 parts, Uncaria sessilifructus Roxb 10 ~ 30 parts, Herba Tricyrtis Pilosae 10 ~ 20 parts, Herba Silenes conoideae 5 ~ 15 parts.
As preferably of the present invention, it is made up of the raw material of following weight proportion: Rhizoma Smilacis Scobinicaulis 50 parts, Herba Centrantherae Cochinchinensis 50 parts, Resina Toxicodendri 30 parts, Caulis Seu Folium Euonymi Fortunei 30 parts, Flos Wikstroemiae Dolichanthae root 40 parts, Lytta caragana Pallas 20 parts, Rhizoma alcasiae odorae 30 parts, Herba Aristolochiae 25 parts, umbrella plant 25 parts, 30 parts, hair and blood rattan, Cortex Illicii 30 parts, Cortex cercis chinensis 25 parts, Cortex Linderae Fragrantis 20 parts, Semen Impatientis 40 parts, Cissus repens 25 parts, Radix Rhodiolae Dumulosae 30 parts, Radix rubi buergeri 20 parts, muntjac grass 30 parts, Herba Corydalis Bungeanae 20 parts, Rhizoma Menispermi 40 parts, Uncaria sessilifructus Roxb 20 parts, Herba Tricyrtis Pilosae 15 parts, Herba Silenes conoideae 10 parts.
The Chinese medicine preparation of a kind of hysteromyoma be used for the treatment of that technical solution of the present invention provides, it is prepared from by the following method:
(1) get Resina Toxicodendri, Lytta caragana Pallas, Herba Aristolochiae, Radix rubi buergeri, Uncaria sessilifructus Roxb be ground into fine powder;
(2) again Rhizoma Smilacis Scobinicaulis, Herba Centrantherae Cochinchinensis, Caulis Seu Folium Euonymi Fortunei, Flos Wikstroemiae Dolichanthae root, Rhizoma alcasiae odorae, umbrella plant, hair and blood rattan, Cortex Illicii, Cortex cercis chinensis, Cortex Linderae Fragrantis, Semen Impatientis, Cissus repens, Radix Rhodiolae Dumulosae, muntjac grass, Herba Corydalis Bungeanae, Rhizoma Menispermi, Herba Tricyrtis Pilosae, Herba Silenes conoideae medical material are merged, adding with medical material weight ratio is the soak by water 1 ~ 3 time of 7 ~ 10 times amount, each 0.5 ~ 2h, filter, merging filtrate, concentrating under reduced pressure becomes thick paste, is ground into dried cream powder, sieve for subsequent use;
(3) get above-mentioned steps (1) in fine powder, step (2) in dried cream powder, fully after mixing, obtain Traditional Chinese drug mixture, then add adjuvant conventional on pharmaceutics and make various different oral formulations, to obtain final product.
As preferably of the present invention, the concrete preparation method of technical solution of the present invention is:
(1) get Resina Toxicodendri, Lytta caragana Pallas, Herba Aristolochiae, Radix rubi buergeri, Uncaria sessilifructus Roxb be ground into (100 order) fine powder;
(2) again Rhizoma Smilacis Scobinicaulis, Herba Centrantherae Cochinchinensis, Caulis Seu Folium Euonymi Fortunei, Flos Wikstroemiae Dolichanthae root, Rhizoma alcasiae odorae, umbrella plant, hair and blood rattan, Cortex Illicii, Cortex cercis chinensis, Cortex Linderae Fragrantis, Semen Impatientis, Cissus repens, Radix Rhodiolae Dumulosae, muntjac grass, Herba Corydalis Bungeanae, Rhizoma Menispermi, Herba Tricyrtis Pilosae, Herba Silenes conoideae medical material are merged, adding with medical material weight ratio is the soak by water 2 times of 9 times amount, each 1h, filter, merging filtrate, concentrating under reduced pressure becomes thick paste, is ground into dried cream powder, sieve for subsequent use;
(3) get above-mentioned steps (1) in fine powder, step (2) in dried cream powder, fully after mixing, obtain Traditional Chinese drug mixture, then add adjuvant conventional on pharmaceutics and make various different oral formulations, to obtain final product.
According to the Chinese medicine preparation of the hysteromyoma in technique scheme obtained by method, finally granule, hard capsule or tablet can be made.
Granule: by gained Traditional Chinese drug mixture, with appropriate dextrin, sucrose, mixing, granulates, dry, makes granule.
Hard capsule: by gained Traditional Chinese drug mixture, adds suitable adjuvant, granulates, encapsulated, makes hard capsule.
Tablet: by gained Traditional Chinese drug mixture, mixes with appropriate amount of starch, dextrin, granulates, is pressed into tablet.
The present invention is under Traditional Chinese medical theory and clinical experience instruct, and through dialectical compatibility, chooses each crude drug component and proportioning thereof.Its each medical material compatibility complements each other using, and has synergism.To adapt to the treatment requirement of the complicated state of an illness, and improve the curative effect of full side.Full side is made to have effect of blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, warming spleen and stomach for dispelling cold, hard masses softening and resolving, reducing swelling and alleviating pain.For hysteromyoma patients undergoing in clinical practice, there is obvious therapeutic effect, strengthening the body resistance effect can be played.In use, this Chinese medicine preparation can strengthen body immunity, has good anti-fibrosis effect, inhibition tumor cell abnormality proliferation, to play antitumor action.Through clinical verification, the effective percentage of the clinical cure of Chinese medicine preparation of the present invention up to 97.4%, have side effect little and more after the advantage that do not recur, and the preparation technology of Chinese medicine preparation of the present invention is simple, and cost is low, has good market application foreground.
Detailed description of the invention
Below the specific embodiment of content of the present invention, for set forth in present specification want the technical scheme of technical solution problem, contributes to those skilled in the art and understand content of the present invention, but the realization of technical solution of the present invention is not limited to these embodiments.
Embodiment 1
(1) get Resina Toxicodendri 30g, Lytta caragana Pallas 20g, Herba Aristolochiae 25g, Radix rubi buergeri 20g, Uncaria sessilifructus Roxb 20g, be ground into 100 order fine powders;
(2) again Rhizoma Smilacis Scobinicaulis 50g, Herba Centrantherae Cochinchinensis 50g, Caulis Seu Folium Euonymi Fortunei 30g, Flos Wikstroemiae Dolichanthae root 40g, Rhizoma alcasiae odorae 30g, umbrella plant 25g, hair and blood rattan 30g, Cortex Illicii 30g, Cortex cercis chinensis 25g, Cortex Linderae Fragrantis 20g, Semen Impatientis 40g, Cissus repens 25g, Radix Rhodiolae Dumulosae 30g, muntjac grass 30g, Herba Corydalis Bungeanae 20g, Rhizoma Menispermi 40g, Herba Tricyrtis Pilosae 15g, Herba Silenes conoideae 10g are merged, adding with medical material weight ratio is the soak by water 2 times of 9 times amount, each 1h, filter, merging filtrate, concentrating under reduced pressure become relative density be 1.32 ~ 1.38 thick paste, be ground into dried cream powder, sieve for subsequent use;
(3) get above-mentioned steps (1) in fine powder, step (2) in dried cream powder, fully after mixing, obtain Traditional Chinese drug mixture, add suitable adjuvant, granulate, encapsulated, make hard capsule.
Embodiment 2
(1) get Resina Toxicodendri 40g, Lytta caragana Pallas 30g, Herba Aristolochiae 20g, Radix rubi buergeri 10g, Uncaria sessilifructus Roxb 30g, be ground into 100 order fine powders;
(2) again Rhizoma Smilacis Scobinicaulis 60g, Herba Centrantherae Cochinchinensis 40g, Caulis Seu Folium Euonymi Fortunei 40g, Flos Wikstroemiae Dolichanthae root 30g, Rhizoma alcasiae odorae 40g, umbrella plant 30g, hair and blood rattan 40g, Cortex Illicii 20g, Cortex cercis chinensis 20g, Cortex Linderae Fragrantis 30g, Semen Impatientis 50g, Cissus repens 20g, Radix Rhodiolae Dumulosae 40g, muntjac grass 20g, Herba Corydalis Bungeanae 30g, Rhizoma Menispermi 50g, Herba Tricyrtis Pilosae 10g, Herba Silenes conoideae 15g are merged, adding with medical material weight ratio is the soak by water 1 time of 10 times amount, each 3h, filter, merging filtrate, concentrating under reduced pressure become relative density be 1.32 ~ 1.38 thick paste, be ground into dried cream powder, sieve for subsequent use;
(3) get above-mentioned steps (1) in fine powder, step (2) in dried cream powder, fully after mixing, obtain Traditional Chinese drug mixture, with appropriate dextrin, sucrose, mixing, granulates, dry, makes granule.
Embodiment 3
(1) get Resina Toxicodendri 20g, Lytta caragana Pallas 10g, Herba Aristolochiae 30g, Radix rubi buergeri 30g, Uncaria sessilifructus Roxb 10g, be ground into 100 order fine powders;
(2) again Rhizoma Smilacis Scobinicaulis 40g, Herba Centrantherae Cochinchinensis 60g, Caulis Seu Folium Euonymi Fortunei 20g, Flos Wikstroemiae Dolichanthae root 50g, Rhizoma alcasiae odorae 20g, umbrella plant 20g, hair and blood rattan 20g, Cortex Illicii 40g, Cortex cercis chinensis 30g, Cortex Linderae Fragrantis 10g, Semen Impatientis 30g, Cissus repens 30g, Radix Rhodiolae Dumulosae 20g, muntjac grass 40g, Herba Corydalis Bungeanae 10g, Rhizoma Menispermi 30g, Herba Tricyrtis Pilosae 20g, Herba Silenes conoideae 5g are merged, adding with medical material weight ratio is the soak by water 3 times of 7 times amount, each 0.5h, filter, merging filtrate, concentrating under reduced pressure become relative density be 1.32 ~ 1.38 thick paste, be ground into dried cream powder, sieve for subsequent use;
(3) get above-mentioned steps (1) in fine powder, step (2) in dried cream powder, fully after mixing, obtain Traditional Chinese drug mixture, mix with appropriate amount of starch, dextrin, granulation, is pressed into tablet.
In order to verify the curative effect of finished product preparation of the present invention further, the finished capsule product agent medicine of preparation in above-mentioned specific embodiment 1 has been carried out corresponding clinical trial by us, existing that report the test is as follows.
Clinical observation and curative effect
1. physical data
The patient accepting hysteromyoma for medical treatment all meets hysteromyoma diagnostic criteria in " obstetrics and gynecology ", amount to 150 examples, after obtaining patient's agreement, be divided into two groups at random, treatment group 78 example, 31 ~ 58 years old age, the mean age (38.48 ± 4.25) year, the course of disease 6 months ~ 6 years, average course of disease (2.92 ± 0.89) year; Matched group 72 example, the minimum 1.2cm of muscular tumor diameter, is 4.8cm to the maximum, average 3.07 ± 0.52cm.Matched group 72 example, 28 ~ 56 years old age, the mean age (40.13 ± 3.87) year, the course of disease 8 months ~ 7 years, average course of disease (2.92 ± 0.89) year; Matched group 72 example, the minimum 1.1cm of muscular tumor diameter, is 5cm to the maximum, average 3.32 ± 0.63cm.The aspects such as two groups of patient ages, the course of disease, muscular tumor sizes, through statistical procedures no significant difference (P > 0.05), have comparability.
2. diagnosis and inclusion criteria
Formulate with reference to related content in hysteromyoma diagnostic criteria in " obstetrics and gynecology ".Enter to organize case and meet following condition: 1. patient can be asymptomatic, or menoxenia, main manifestations is menorrhagia, menostaxis, and menstrual cycle shortens, and can accompany leucorrhoea grow in quantity, hypogastralgia, the soreness of waist, lower abdomen falling inflation, secondary anemia etc.Tongue is dark violet ecchymosis, stringy and thready pulse or carefully puckery.2. gynecologial examination: the irregular increase in uterus is as within pregnant 2 first quarter moon sizes, and matter is hard, and there is spherical or nodositas projection on surface, smooth, without being adhered.B ultrasonic is diagnosed as single-shot or multiple myomata, and single muscular tumor diameter is less than 5 ㎝.3. lab testing: routine test hemoglobin and hepatic and renal function.Be not in the mood for, brain, liver, kidney important organ disease, and all require non-operative treatment sick, be ready partner treatment person.
3. Therapeutic Method:
Matched group: give GUIZHI FULING JIAONANG (Kangyuan Pharmaceutical Co., Ltd., Jiangsu Prov) oral medication, 3 tablets/time, 3 times/d, menstrual phase is withdrawn.Within 3 months, be a course for the treatment of, after serveing on 2 courses for the treatment of, check B ultrasonic.
Treatment group: capsule 3 tablets/time prepared by the oral embodiment of the present invention 1,3 times/d, menstrual phase is withdrawn.Within 3 months, be a course for the treatment of, after serveing on 2 courses for the treatment of, check B ultrasonic.Observation index: the change of menstruation, comprises through situations such as amount and menstruation recoveries.Hysteromyoma change in volume.Treat front and the rear 3-6 for the treatment of equal B ultrasonic monitoring hysteromyoma number and muscular tumor volume after individual month three-dimensional warp, namely length, width and height calculate the volume of hysteromyoma.To the patient of multiple myomata, hysteromyoma altogether volume is each muscular tumor volume sum.Lab testing: the index etc. of monitoring hemoglobin and hepatic and renal function before and after treatment.
4. efficacy assessment standard
Judge curative effect according to " new Chinese medicine guideline of clinical investigations ", cure: B ultrasonic shows that hysteromyoma disappears, clinical symptom disappearance; Effective: B ultrasonic shows that hysteromyoma reduces 1.5 more than ㎝, clinical symptom relief or disappearance; Effective: B ultrasonic shows that hysteromyoma reduces 0.5 ~ 1.5 ㎝, and clinical symptoms is without improvement, or hysteromyoma is unchanged, clinical symptom disappearance; Invalid: muscular tumor is unchanged or increase, and clinical symptoms is without improvement.
5. therapeutic outcome
Table 1 liang group Clinical efficacy comparison
| Group | n | Recovery from illness | Effective | Effectively | Invalid | Total effective rate |
| Treatment group | 78 | 22 | 30 | 24 | 2 | 97.4% |
| Matched group | 72 | 11 | 18 | 23 | 20 | 72.2% |
From the experimental result of table 1, Chinese medicine preparation total effective rate of the present invention is 97.4%, and the patient's effective percentage taking matched group (GUIZHI FULING JIAONANG) is 72.2%.Result shows, the clinical efficacy of Chinese medicine preparation of the present invention in treatment hysteromyoma disease is remarkable, is obviously better than matched group.And in therapeutic process, do not find whole body and local untoward reaction, and in the patient of clinical cure, leave hospital latter 6 months, pay a return visit, and treatment group find no the situation of recurrence.
Table 2 liang group hysteromyoma volume ratio comparatively mm
3(x ± s)
| Group | n | Before treatment | After treatment |
| Treatment group | 78 | 52.83±16.51 | 21.62±8.53 |
| Matched group | 72 | 51.31±18.36 | 36.28±7.98 |
From the experimental result of table 2, after two groups of patients take 2 courses for the treatment of of GUIZHI FULING JIAONANG of capsule prepared by the embodiment of the present invention 1 and matched group, compared with before treatment, Chinese medicine preparation of the present invention has significant reduction to accepting patient uterine's muscular tumor volume for medical treatment, and the clinical symptoms of patient also improves significantly.Chinese medicine preparation therapeutic effect of the present invention is better than matched group.
In sum: Chinese medicine preparation of the present invention is in treatment hysteromyoma disease, and have significant curative effect, relapse rate is low, the advantage that toxic and side effects is little, and clinic is applied.
Claims (6)
1. treat the Chinese medicine preparation of hysteromyoma for one kind, it is characterized in that it is made up of the raw material of following weight proportion: Rhizoma Smilacis Scobinicaulis 40 ~ 60 parts, Herba Centrantherae Cochinchinensis 40 ~ 60 parts, Resina Toxicodendri 20 ~ 40 parts, Caulis Seu Folium Euonymi Fortunei 20 ~ 40 parts, Flos Wikstroemiae Dolichanthae root 30 ~ 50 parts, Lytta caragana Pallas 10 ~ 30 parts, Rhizoma alcasiae odorae 20 ~ 40 parts, Herba Aristolochiae 20 ~ 30 parts, umbrella plant 20 ~ 30 parts, 20 ~ 40 parts, hair and blood rattan, Cortex Illicii 20 ~ 40 parts, Cortex cercis chinensis 20 ~ 30 parts, Cortex Linderae Fragrantis 10 ~ 30 parts, Semen Impatientis 30 ~ 50 parts, Cissus repens 20 ~ 30 parts, Radix Rhodiolae Dumulosae 20 ~ 40 parts, Radix rubi buergeri 10 ~ 30 parts, muntjac grass 20 ~ 40 parts, Herba Corydalis Bungeanae 10 ~ 30 parts, Rhizoma Menispermi 30 ~ 50 parts, Uncaria sessilifructus Roxb 10 ~ 30 parts, Herba Tricyrtis Pilosae 10 ~ 20 parts, Herba Silenes conoideae 5 ~ 15 parts.
2. treat the Chinese medicine preparation of hysteromyoma as claimed in claim 1, it is characterized in that it is made up of the raw material of following weight proportion: Rhizoma Smilacis Scobinicaulis 50 parts, Herba Centrantherae Cochinchinensis 50 parts, Resina Toxicodendri 30 parts, Caulis Seu Folium Euonymi Fortunei 30 parts, Flos Wikstroemiae Dolichanthae root 40 parts, Lytta caragana Pallas 20 parts, Rhizoma alcasiae odorae 30 parts, Herba Aristolochiae 25 parts, umbrella plant 25 parts, 30 parts, hair and blood rattan, Cortex Illicii 30 parts, Cortex cercis chinensis 25 parts, Cortex Linderae Fragrantis 20 parts, Semen Impatientis 40 parts, Cissus repens 25 parts, Radix Rhodiolae Dumulosae 30 parts, Radix rubi buergeri 20 parts, muntjac grass 30 parts, Herba Corydalis Bungeanae 20 parts, Rhizoma Menispermi 40 parts, Uncaria sessilifructus Roxb 20 parts, Herba Tricyrtis Pilosae 15 parts, Herba Silenes conoideae 10 parts.
3. treat the preparation method of the Chinese medicine preparation of hysteromyoma as claimed in claim 1 or 2, it is characterized in that:
(1) get Resina Toxicodendri, Lytta caragana Pallas, Herba Aristolochiae, Radix rubi buergeri, Uncaria sessilifructus Roxb be ground into fine powder;
(2) again Rhizoma Smilacis Scobinicaulis, Herba Centrantherae Cochinchinensis, Caulis Seu Folium Euonymi Fortunei, Flos Wikstroemiae Dolichanthae root, Rhizoma alcasiae odorae, umbrella plant, hair and blood rattan, Cortex Illicii, Cortex cercis chinensis, Cortex Linderae Fragrantis, Semen Impatientis, Cissus repens, Radix Rhodiolae Dumulosae, muntjac grass, Herba Corydalis Bungeanae, Rhizoma Menispermi, Herba Tricyrtis Pilosae, Herba Silenes conoideae medical material are merged, adding with medical material weight ratio is the soak by water 1 ~ 3 time of 7 ~ 10 times amount, each 0.5 ~ 2h, filter, merging filtrate, concentrating under reduced pressure becomes thick paste, is ground into dried cream powder, sieve for subsequent use;
(3) get above-mentioned steps (1) in fine powder, step (2) in dried cream powder, fully after mixing, obtain Traditional Chinese drug mixture, then add adjuvant conventional on pharmaceutics and make various different oral formulations, to obtain final product.
4. treat the preparation method of the Chinese medicine preparation of hysteromyoma as claimed in claim 3, it is characterized in that:
(1) get Resina Toxicodendri, Lytta caragana Pallas, Herba Aristolochiae, Radix rubi buergeri, Uncaria sessilifructus Roxb be ground into (100 order) fine powder;
(2) again Rhizoma Smilacis Scobinicaulis, Herba Centrantherae Cochinchinensis, Caulis Seu Folium Euonymi Fortunei, Flos Wikstroemiae Dolichanthae root, Rhizoma alcasiae odorae, umbrella plant, hair and blood rattan, Cortex Illicii, Cortex cercis chinensis, Cortex Linderae Fragrantis, Semen Impatientis, Cissus repens, Radix Rhodiolae Dumulosae, muntjac grass, Herba Corydalis Bungeanae, Rhizoma Menispermi, Herba Tricyrtis Pilosae, Herba Silenes conoideae medical material are merged, adding with medical material weight ratio is the soak by water 2 times of 9 times amount, each 1h, filter, merging filtrate, concentrating under reduced pressure becomes thick paste, is ground into dried cream powder, sieve for subsequent use;
(3) get above-mentioned steps (1) in fine powder, step (2) in dried cream powder, fully after mixing, obtain Traditional Chinese drug mixture, then add adjuvant conventional on pharmaceutics and make various different oral formulations, to obtain final product.
5. treat the preparation method of the Chinese medicine preparation of hysteromyoma as claimed in claim 4, it is characterized in that: described step (3) in Traditional Chinese drug mixture be to add on pharmaceutics granule, hard capsule, the tablet that conventional pharmaceutic adjuvant makes.
6. the application of Chinese medicine preparation as claimed in claim 1 in preparation treatment hysteromyoma medicine.
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| CN201510458053.2A Pending CN104984020A (en) | 2015-07-30 | 2015-07-30 | Traditional Chinese medicinal preparation for treating hysteromyoma, and preparation method thereof |
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| CN105878943A (en) * | 2016-06-23 | 2016-08-24 | 张莉 | Traditional Chinese medicine preparation for treating uterine myoma |
| CN106212822A (en) * | 2016-08-18 | 2016-12-14 | 浙江正宇健康科技有限公司 | A kind of cancer-resisting health tea |
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| EP2082746A1 (en) * | 2008-01-25 | 2009-07-29 | Bozcuk, Hakan | Extract from Urginea Maritima for use in the treatment of non small cell lung cancer (NSCLC) and other solid tumors |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105878943A (en) * | 2016-06-23 | 2016-08-24 | 张莉 | Traditional Chinese medicine preparation for treating uterine myoma |
| CN106212822A (en) * | 2016-08-18 | 2016-12-14 | 浙江正宇健康科技有限公司 | A kind of cancer-resisting health tea |
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Application publication date: 20151021 |